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MATGGTPPLSVDPEELSAAGGALLDSARELPQAPAPFNPVGTDPLSAAIIGQIPAVEAPIATQLPLIQAQ ATSTAQNVVSAAQVYAETDARNGAAIHEQMQSRLDPLGTGSGGGSLPSTAGGGADSLGMPMQMAGQMAQM PMQVMGAVAAVPQGIMQGAQQAGQQVQQMVGQFGDQGAKDGQKGTPSGELPTAANREEGAAAAEPHAERA PEPEEKTDTDGGQRPGRHRAAESDERIEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0082 | - | - | 100% (239) | hypothetical protein Mvan_0082 |
| M. vanbaalenii PYR-1 | Mvan_4513 | - | 2e-10 | 29.22% (243) | hypothetical protein Mvan_4513 |
| M. vanbaalenii PYR-1 | Mvan_0077 | - | 1e-05 | 27.84% (176) | PPE protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3908 | - | 1e-18 | 32.65% (245) | hypothetical protein Mb3908 |
| M. gilvum PYR-GCK | Mflv_0763 | - | 4e-76 | 60.98% (246) | hypothetical protein Mflv_0763 |
| M. tuberculosis H37Rv | Rv3878 | - | 1e-18 | 32.65% (245) | hypothetical protein Rv3878 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5453 | - | 2e-15 | 29.79% (235) | hypothetical protein MMAR_5453 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0069 | - | 1e-19 | 32.13% (221) | translation initiation factor IF-2 protein |
| M. thermoresistible (build 8) | TH_2875 | - | 8e-19 | 33.33% (231) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2551 | - | 7e-12 | 28.92% (204) | hypothetical protein MUL_2551 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0082|M.vanbaalenii_PYR-1 MATGGTPPLSVDPEELSAAGGALLDSARELPQAPAPFNPVGTDPLSAAII
Mflv_0763|M.gilvum_PYR-GCK MVSGGLPPLSVDPTQLSAAGGALKSSALDLPEAPAPFMPVGTDPLSVAII
Mb3908|M.bovis_AF2122/97 ----MAEPLAVDPTGLSAAAAKLAG--LVFPQPPAPIAVSGTDSVVAAIN
Rv3878|M.tuberculosis_H37Rv ----MAEPLAVDPTGLSAAAAKLAG--LVFPQPPAPIAVSGTDSVVAAIN
MMAR_5453|M.marinum_M ----MAEPLAVDPARLIAAGSKLAE--LVFPAPPAPIAATGGDPVSAAIN
MUL_2551|M.ulcerans_Agy99 ----MAKELVIDSSRLKIAGIDLAE--LTLPTPPPPILATGLDSASAAIN
TH_2875|M.thermoresistible__bu ---------------LTAAISERIT---EVVDPVIEALPVTKEELKQFAQ
MSMEG_0069|M.smegmatis_MC2_155 ---------------MEASAR-------AIPEPPDPFKTEGTDPLSKALA
: : . . :
Mvan_0082|M.vanbaalenii_PYR-1 GQIPAVEAPIATQLPLIQAQATSTAQNVVSAAQVYAETDARNGAAIHEQM
Mflv_0763|M.gilvum_PYR-GCK GQIPAIETPIATQLPLIKAEATTTASNVEDAAQAYAATDEQNSAAIDQVM
Mb3908|M.bovis_AF2122/97 KTMPSIESLVSDGLPGVKAALTRTASNMNAAADVYAKTDQSLGTSLSQYA
Rv3878|M.tuberculosis_H37Rv ETMPSIESLVSDGLPGVKAALTRTASNMNAAADVYAKTDQSLGTSLSQYA
MMAR_5453|M.marinum_M DTMPGIESLVSDGMPGVTAALKRTASSMSTAADIYAKADQALGDALTQYQ
MUL_2551|M.ulcerans_Agy99 AILPIIESPVADSLPVVNSALTKTGSNFVAAAAIYAEADQSLGEQLGQFQ
TH_2875|M.thermoresistible__bu NVVSAADEYDAKDRQIAEEILKQIGAFDEPPAHGGAVPSGGSSAVTGPSS
MSMEG_0069|M.smegmatis_MC2_155 DKTWQVEAPFIEGIGKTKAEAQETARRIQEAADKYEQSDRTIAENLQSST
: . .* .. .
Mvan_0082|M.vanbaalenii_PYR-1 QSRLDP----------LGTGSGGGSL-----PSTAGGGADSLG-------
Mflv_0763|M.gilvum_PYR-GCK QKTPSQ----------MPSGSGG---------SAPGGGADAAG-------
Mb3908|M.bovis_AF2122/97 FGSSGEGLAG------VASVGGQPSQ-----ATQLLSTPVSQ--------
Rv3878|M.tuberculosis_H37Rv FGSSGEGLAG------VASVGGQPSQ-----ATQLLSTPVSQ--------
MMAR_5453|M.marinum_M FGGDGQALGASGANAVAQSQAGQTVQSLAAPAAGLLGAPVAQALAAPATG
MUL_2551|M.ulcerans_Agy99 FRS-------------AATTSEYAAR-----GNALMAGSAALG-------
TH_2875|M.thermoresistible__bu PLSAAG------------ASVGGMTG------ASVGGAAGQAG-------
MSMEG_0069|M.smegmatis_MC2_155 GRFDAS------------TGTEGTSQ---------GGLQGLEQ-------
: .
Mvan_0082|M.vanbaalenii_PYR-1 ------MPMQMAG------------QMAQMPMQVMGAVAAVPQGIMQGAQ
Mflv_0763|M.gilvum_PYR-GCK ------QMSQMMGMP---------MQMAQMPMQMMSGIASAPQGLMQGAQ
Mb3908|M.bovis_AF2122/97 -------VTTQLGET----AAELAPR-VVATVPQLVQLAPHAVQMSQNAS
Rv3878|M.tuberculosis_H37Rv -------VTTQLGET----AAELAPR-VVATVPQLVQLAPHAVQMSQNAS
MMAR_5453|M.marinum_M LLGVPAAAATQIGEAVSAQAEALSPR-VAATIPQLVQLAPQAGQMAQQAS
MUL_2551|M.ulcerans_Agy99 --------YGLAAEP----EIPIASRFTLPTMAQMGSLPGQAATLSGHTS
TH_2875|M.thermoresistible__bu ------GFEQMMGMP-----MQMAQQAAQMPMQMGGMAGQLPQQLAQGAQ
MSMEG_0069|M.smegmatis_MC2_155 -------LQQMMQMP---------MQAVQMAAQVPTQMAQMAAQVPQTVM
: . . . : .
Mvan_0082|M.vanbaalenii_PYR-1 QAGQQVQQMVGQFGDQGAKDGQKG----TPSGELP---------------
Mflv_0763|M.gilvum_PYR-GCK QASQQVQQMAGQFG-QGATGGSASSAAQVPAPDAP---------------
Mb3908|M.bovis_AF2122/97 PIAQTISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTNDDQ
Rv3878|M.tuberculosis_H37Rv PIAQTISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTNDDQ
MMAR_5453|M.marinum_M PIAQTISQSAQQG--SSQG--GAAPAQLVSDTKPD-EDAELADETK---E
MUL_2551|M.ulcerans_Agy99 QYANLVNQTMGQL----QG-------------------------------
TH_2875|M.thermoresistible__bu GAMEQVTQLSGLADGDQQGLGDDQAGEAVDGVMS----------------
MSMEG_0069|M.smegmatis_MC2_155 QGVQQIGQMSGGTGQDSAGPAAPQTDSPVGKSKGG---------------
: : *
Mvan_0082|M.vanbaalenii_PYR-1 -----------TAANREEGAAAAEPHAERAPEPEEKTDTDGGQRPGRHRA
Mflv_0763|M.gilvum_PYR-GCK -----------APEPASEGAAAGEPDAERAPTPDERSDREDTGAPGRHRA
Mb3908|M.bovis_AF2122/97 GDQGDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAGARPAASPL
Rv3878|M.tuberculosis_H37Rv GDQGDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAGARPAASPL
MMAR_5453|M.marinum_M GEE------DAMAAAGAEGAAAGHATL----VSAPVESTGGGETSTGS-V
MUL_2551|M.ulcerans_Agy99 -----------VASMAQQGPGT---------APEPAED-GPVLQPEH---
TH_2875|M.thermoresistible__bu -----------EQASAEPESQIPAAVAEQQEQTDQPGERAPVGSPSARSA
MSMEG_0069|M.smegmatis_MC2_155 -------RERDDQQEQHEGAAADPAFTQQAPVTSQVPGAAASEPEAGHSE
. .
Mvan_0082|M.vanbaalenii_PYR-1 AESDERIEL------------
Mflv_0763|M.gilvum_PYR-GCK AEADDRIDL------------
Mb3908|M.bovis_AF2122/97 AAPVDPSTPAPSTTTTL----
Rv3878|M.tuberculosis_H37Rv AAPVDPSTPAPSTTTTL----
MMAR_5453|M.marinum_M SAPI-----------------
MUL_2551|M.ulcerans_Agy99 ---------------------
TH_2875|M.thermoresistible__bu VSDAEIVL-------------
MSMEG_0069|M.smegmatis_MC2_155 GRPRANGTVPRPVPSDPAIVL