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VSRLIVAPDWLASAAAEVQSIGSALSAANAAAAAPTTLLVAAAEDEVSAAAAALFANYGREYQTLSVRFA SLDQQFAQALNSAAASYQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGTAASPIGEPGGI LYGDGGNGYSQTTPGAVGGAGGSAGFIGNGGAAGAGGPGAGGGTGGLGGWLWGNNGAAGTGDPVNVAVPL RVENNFPLVNLLVNRGPTVPILLDTGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVDF GGGAATTPTSVHVGILPYPRNLDSLVLIASGGAFGPNGNGILGIGPNVGSYAVSGPGNVVTTDLPGQLNE GTLIDIPGGYMQFGPNTGTPITSVTGAPITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGTGQ TTGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNYP PP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2548 | PE26 | - | 100% (492) | PE family protein |
| M. bovis AF2122 / 97 | Mb2005 | PE_PGRS35 | 2e-68 | 64.68% (201) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | 1e-64 | 38.98% (449) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2178 | - | 1e-14 | 47.78% (90) | hypothetical protein Mflv_2178 |
| M. tuberculosis H37Rv | Rv2519 | PE26 | 0.0 | 99.80% (492) | PE family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-08 | 34.52% (84) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0112 | - | 9e-07 | 33.98% (103) | hypothetical protein MAB_0112 |
| M. marinum M | MMAR_1538 | - | 0.0 | 68.90% (492) | PE family protein, PE26 |
| M. avium 104 | MAV_1346 | - | 1e-14 | 30.60% (232) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-21 | 46.15% (117) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-09 | 29.63% (189) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2395 | - | 1e-132 | 62.27% (379) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 6e-23 | 55.24% (105) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2178|M.gilvum_PYR-GCK MSG--TAHAPGKTRLFANVTVAVGLGGAALG--AAALLAP--QASAAPEE
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGNGGSDDDAADDSEK
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK WLP----------AGPSSECPPPT-----DGCAN----------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPASTESTEQSADVANDA
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK VAAVGGVHGAQGPANLATPQTS---GSPLFRPLFG-------------NG
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLINSLWWAV
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK ADAPADC-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M ----------------------------------------MRAEQTVRQR
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 PKSGGR--------------------------------------------
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------------VGNACN---
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M RCRRRSITPTWEVRHGQHLRVCAVRNRAGSQCRPSSTPHNTTFARTHRIE
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -----------STNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTE
MAB_0112|M.abscessus_ATCC_1997 ---------------------------------MLFAVGRHRANPSRRSQ
Mflv_2178|M.gilvum_PYR-GCK ----GRDGGLIWGNGGAGAN-------GGHGGNAGLVGNGGRGGD-----
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL
TH_3810|M.thermoresistible__bu ----------VDGD-------------GGSGGRTGLFSKLSRGGD-----
Mb2548|M.bovis_AF2122/97 ------------------------------------MSRLIVAPD-----
Rv2519|M.tuberculosis_H37Rv ------------------------------------MSRLIVAPD-----
MMAR_1538|M.marinum_M IGALGNDEKRRLSRNHWGYLDETAGDVDNHDRTGVGVAQLSVAPP-----
MUL_2395|M.ulcerans_Agy99 ------------------------------------MAQLSVAPP-----
MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFLNAEPQ-----
MAV_1346|M.avium_104 -----------------------------------MS-FVTTRPE-----
Mvan_0928|M.vanbaalenii_PYR-1 QNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLWGSGGDGG-----
MAB_0112|M.abscessus_ATCC_1997 QLKRASARAAVVTVLSSGTLMGGFGVFAITTPAADAKPGGGSGND-----
Mflv_2178|M.gilvum_PYR-GCK -----------------------------ATTPGRSGGHGGNGG------
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
TH_3810|M.thermoresistible__bu ---------------------------------GGDGGLGGNGG------
Mb2548|M.bovis_AF2122/97 ------------------------------WLASAAAEVQSIGS------
Rv2519|M.tuberculosis_H37Rv ------------------------------WLASAAAEVQSIGS------
MMAR_1538|M.marinum_M ------------------------------WLVSAAQDLQSIGS------
MUL_2395|M.ulcerans_Agy99 ------------------------------WLVSAAQDLQSIGS------
MLBr_01183|M.leprae_Br4923 ------------------------------ALTAAANTLEGLSA------
MAV_1346|M.avium_104 ------------------------------ALLAVASMLEGLGS------
Mvan_0928|M.vanbaalenii_PYR-1 -----------------------------AGGAGAAGGTGGNAG------
MAB_0112|M.abscessus_ATCC_1997 ----------------------------HDHDHGLGGALHKLTG------
. .
Mflv_2178|M.gilvum_PYR-GCK ----------------------RLWGNGGDGGNGAPGVLGPAGTAPIPPS
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
TH_3810|M.thermoresistible__bu --------------------------HGG--GTGIISLLSLAG-------
Mb2548|M.bovis_AF2122/97 -----------------------ALSAANAAAAAPTTLLVAAAEDEVSAA
Rv2519|M.tuberculosis_H37Rv -----------------------ALSAANAAAAAPTTLLVAAAEDEVSAA
MMAR_1538|M.marinum_M -----------------------TLAAANGAAAGPTTVLATAAADEVSTA
MUL_2395|M.ulcerans_Agy99 -----------------------TLAAANGAAAGPTTVLATAAADEVSTA
MLBr_01183|M.leprae_Br4923 -----------------------ATVASNAAAAQLTTEIAPPAADDVSIL
MAV_1346|M.avium_104 -----------------------SMDAQNAAAAAPTTSIAPAAADEVSAL
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------LLWGNGGHGGAGGAGVNGAVGTSGVNNG
MAB_0112|M.abscessus_ATCC_1997 -----------------------GLLGGGGGGNGGPGSGGARNAPSAPSF
. .
Mflv_2178|M.gilvum_PYR-GCK SLPAATG----TRGDSPPYG------------------------YGNLVG
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
TH_3810|M.thermoresistible__bu --NGGNG----GNGYRTTDN-------------------------NALDG
Mb2548|M.bovis_AF2122/97 AAALFAN-------------------------------------YGREYQ
Rv2519|M.tuberculosis_H37Rv AAALFAN-------------------------------------YGREYQ
MMAR_1538|M.marinum_M IAALFAG-------------------------------------HAREYH
MUL_2395|M.ulcerans_Agy99 IAALFAG-------------------------------------HAREYH
MLBr_01183|M.leprae_Br4923 LAHFFSG-------------------------------------HGRQYQ
MAV_1346|M.avium_104 QAAQFSA-------------------------------------YGTWYQ
Mvan_0928|M.vanbaalenii_PYR-1 RGGDGTAGGSGGAGGNAG--------------------------LLSGRG
MAB_0112|M.abscessus_ATCC_1997 GKSLHGG--------------------------------------SGSEG
Mflv_2178|M.gilvum_PYR-GCK GDGGTGADGGRYAFGAN----------------------------WSLDL
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGT
TH_3810|M.thermoresistible__bu GHGGNGGNVG-----------------------------------FFSLF
Mb2548|M.bovis_AF2122/97 TLSVRFASLDQQFAQALN----------------------------SAAA
Rv2519|M.tuberculosis_H37Rv TLSVRFASLDQQFAQALN----------------------------SAAA
MMAR_1538|M.marinum_M SLSGHFGAFNQQFVQALN----------------------------SASG
MUL_2395|M.ulcerans_Agy99 SLSGHFGAFNQQFVQALN----------------------------SASG
MLBr_01183|M.leprae_Br4923 AHASQGATNHQDLIQSLL----------------------------TSSS
MAV_1346|M.avium_104 QVSAQAKAIHQTLVQNLD----------------------------TNAD
Mvan_0928|M.vanbaalenii_PYR-1 GDGGVGGAGGKGGAGAHG-------------------------SDAVAAE
MAB_0112|M.abscessus_ATCC_1997 AAGGNGDSAKSDKDKDKG--------------------------PGASVP
.
Mflv_2178|M.gilvum_PYR-GCK PVGGAGGAG-----GWANSIDGSATGGNGGD-------------------
MSMEG_0868|M.smegmatis_MC2_155 GIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGA
TH_3810|M.thermoresistible__bu NLGGAGGWG-------GSGVDGVDVVGGNPD-------------------
Mb2548|M.bovis_AF2122/97 SYQTAEATGASLVQTATQGVLGVINAPTEFM-------------------
Rv2519|M.tuberculosis_H37Rv SYQTAEATGASLVQTATQGVLGVINAPTEFM-------------------
MMAR_1538|M.marinum_M AYASAEAQSAPLLQTVGRDVLGAINAPTEFL-------------------
MUL_2395|M.ulcerans_Agy99 AYASAEAQSASLLQTVGRDVLGAINAPTEFL-------------------
MLBr_01183|M.leprae_Br4923 AYAGTETAN-----------------------------------------
MAV_1346|M.avium_104 SYGATEAANRVNTSAAALQGLAPNVIPNAAP-------------------
Mvan_0928|M.vanbaalenii_PYR-1 EDGGPGGSGGAGGNAGAGGVGGRGALLFGRG-------------------
MAB_0112|M.abscessus_ATCC_1997 KPGSAGSTGKTADSAAGSAGSGTGTPGANSS-------------------
.
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK -GGNGAFGGRGGNGG-------------------------------AGG-
MSMEG_0868|M.smegmatis_MC2_155 HGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGN
TH_3810|M.thermoresistible__bu -------GGTPGAHG-----------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK -----------------SAYGRGGITTGGNGGAGG---------------
MSMEG_0868|M.smegmatis_MC2_155 GGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGT
TH_3810|M.thermoresistible__bu ------------------ESHTPGVYTDRQGEDGE---------------
Mb2548|M.bovis_AF2122/97 ------------FGRSLIGDGADGTAASPIGEPGGILYGDGGNGYSQTTP
Rv2519|M.tuberculosis_H37Rv ------------FGRSLIGDGADGTAASPIGEPGGILYGDGGNGYSQTTP
MMAR_1538|M.marinum_M ------------LARPLIGNGADGTAANPNGGAGGLLIGNGGNGYSQTTP
MUL_2395|M.ulcerans_Agy99 ------------LGRPLIGNGADGTAANPNGGAGGLLIGNGG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------AADPPP--------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -------------GDGGDGGSAGTGGAGGFGGTGGAIVVTLP--------
MAB_0112|M.abscessus_ATCC_1997 -----------------APGGSNGSSGGGIGGVGTTVG------------
Mflv_2178|M.gilvum_PYR-GCK -----------------HGSTGAAGGRGGDGASAS----------GGYAV
MSMEG_0868|M.smegmatis_MC2_155 TIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDT
TH_3810|M.thermoresistible__bu -----------------DGTGTGIGGRGGNGGSSS--------GTHPMAE
Mb2548|M.bovis_AF2122/97 GAVGGAGGSAGFIGNGGAAGAGGPGAGGGTGGLGG-------------WL
Rv2519|M.tuberculosis_H37Rv GAVGGAGGSAGFIGNGGAGGAGGPGAGGGTGGLGG-------------WL
MMAR_1538|M.marinum_M GLTGGTGGTAGLIGNGGSGGAGGPNAAGGPGGLGG-------------WL
MUL_2395|M.ulcerans_Agy99 -----------------SGGARGPNAAGGPGGLGG-------------WL
MLBr_01183|M.leprae_Br4923 --------------------HDSL--------------------------
MAV_1346|M.avium_104 ------------------AGTTSLGTSIGWAQNVG-------------AA
Mvan_0928|M.vanbaalenii_PYR-1 --------------GGKLSDSDGAGGAGGVGGAAG--------------L
MAB_0112|M.abscessus_ATCC_1997 ------------------TTLPHSGGAAGVHTPTAEG-----------AA
Mflv_2178|M.gilvum_PYR-GCK GGNGGDGGRGG----AGATG------------GTGGTGGAGGDGGRGG--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDG
TH_3810|M.thermoresistible__bu DGEHVKALDGR----PGLDG------------GNGSHGGNGGHGGRGGFL
Mb2548|M.bovis_AF2122/97 WGNNGAAGTGDPVNVAVPLR------------VENNFPLVNLLVNRGPTV
Rv2519|M.tuberculosis_H37Rv WGNNGAAGTGDPVNVAVPLR------------VENNFPLVNLLVNRGPTV
MMAR_1538|M.marinum_M YGNNGPAGTGSPVNASVPLY------------LDNNFPAVNVSINGGPSV
MUL_2395|M.ulcerans_Agy99 YGNNGPAGTGSPVNASVPLY------------LDNNFPAVNVSINGGPSV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ASDFITLGEGQFAPVPGAAG------------IPNFNPGLTAATTAGPPA
Mvan_0928|M.vanbaalenii_PYR-1 GGDGGGGGLGGLLGQAGVNGDSGATAAAG---NAGGVGGAGGLGGRLPIV
MAB_0112|M.abscessus_ATCC_1997 ATESSAGTGTHTEEHPSLKG------------ALGSVAGALAPKTETATT
Mflv_2178|M.gilvum_PYR-GCK LLGGHGGKG----GNAGLGGNGGTGG------------------------
MSMEG_0868|M.smegmatis_MC2_155 ALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGR
TH_3810|M.thermoresistible__bu GIGGSGGWG-------GHGGNGGDTD------------------------
Mb2548|M.bovis_AF2122/97 PILLDTGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVD
Rv2519|M.tuberculosis_H37Rv PILLDTGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVD
MMAR_1538|M.marinum_M PVLLDTGSAGLVVPIWDIGLQNLGVPTGFDVIRYGNGVNILYADFNTTVD
MUL_2395|M.ulcerans_Agy99 PVLLDIGSAGLVVPIWDIGLQDLGLPTGFDVIRYGNGVNILYADFNTTVD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PAAPAAAAGAPVLASMGRGPSIG---------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DLNNASPAQATLAALIKKLGLPIQAATGIQLEDVDGRLVGPLNAYLYNTI
MAB_0112|M.abscessus_ATCC_1997 PKTETATSPHTSTAPGATAETPTAGTTHPEHESSAEEPKVPGVTVNMGGR
Mflv_2178|M.gilvum_PYR-GCK ------------TGGVGGDGGVG---------------------------
MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNA
TH_3810|M.thermoresistible__bu -----------ADGGNGGDGGNG---------------------------
Mb2548|M.bovis_AF2122/97 FGGGAATTPTSVHVGILPYPRNLDS-------------------------
Rv2519|M.tuberculosis_H37Rv FGGGAATTPTSVHVGILPYPRNLDS-------------------------
MMAR_1538|M.marinum_M FGSGAVTAPTSVQVGILPFPTSLQG-------------------------
MUL_2395|M.ulcerans_Agy99 FGSGAVTAPTSVQVGILPFPTSLQG-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---GLSVPPSWAPGGVAPAANATPA-------------------------
Mvan_0928|M.vanbaalenii_PYR-1 IGKAIFDVGNTFSSASLSARVKEIVILSVGG-------------------
MAB_0112|M.abscessus_ATCC_1997 TIIIWKKKPSTSTHTPGAGTGTNPG-------------------------
Mflv_2178|M.gilvum_PYR-GCK -----------GGILTATG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ----------QWGSEYELYAHKLAAQLFGIPADAIAALANGQAPVGLSGN
MAB_0112|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK -------------------------VVGAGGSGG---AGGTGGRGGD---
MSMEG_0868|M.smegmatis_MC2_155 GINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVV
TH_3810|M.thermoresistible__bu ------------------------GSAGRGGTGG--LRGVFGINGGNG--
Mb2548|M.bovis_AF2122/97 -----------------------LVLIASGGAFGPNGNGILGIGPNVGS-
Rv2519|M.tuberculosis_H37Rv -----------------------LVLIASGGAFGPNGNGILGIGPNVGS-
MMAR_1538|M.marinum_M -----------------------LTLIAMGNGFGPTGHGVLGIGPNIN--
MUL_2395|M.ulcerans_Agy99 -----------------------LTLIAMGNGFGPTGHGVLGIGPNIN--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------QLVGAGFTSAAPDTAPVTAVPGGVPS-
Mvan_0928|M.vanbaalenii_PYR-1 ELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLAGTYLGVSAT
MAB_0112|M.abscessus_ATCC_1997 ------------------------HESEGDRDHVINLPGFPALGGATNP-
Mflv_2178|M.gilvum_PYR-GCK -----------------GGDGGQAG-------------------------
MSMEG_0868|M.smegmatis_MC2_155 NTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGN
TH_3810|M.thermoresistible__bu ----------------RAGLGGRGXXX-----------------------
Mb2548|M.bovis_AF2122/97 --------------YAVSGPGNVVTTDLPG--------------------
Rv2519|M.tuberculosis_H37Rv --------------YAVSGPGNVVTTDLPG--------------------
MMAR_1538|M.marinum_M --------------AATGGHGNVVTTALPG--------------------
MUL_2395|M.ulcerans_Agy99 --------------VAAGGHGNVVTTALPG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------MATAGRGGYGLGAPRY--------------------
Mvan_0928|M.vanbaalenii_PYR-1 LN-----------AFKVRGPESFSAPVLPAAPSPVP--------------
MAB_0112|M.abscessus_ATCC_1997 -------------DAPFGGAAGTRTPGGNP--------------------
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------------RGGAGGLAG
MSMEG_0868|M.smegmatis_MC2_155 ATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAAT
TH_3810|M.thermoresistible__bu -----------------------------------------XGGGVGAAV
Mb2548|M.bovis_AF2122/97 -----------------------------------------QLNEGTLID
Rv2519|M.tuberculosis_H37Rv -----------------------------------------QLNEGTLID
MMAR_1538|M.marinum_M -----------------------------------------QLNEGELIN
MUL_2395|M.ulcerans_Agy99 -----------------------------------------QLNEGELIN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------------------GVKPTVMPK
Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------ASDEYGLGGRLPL
MAB_0112|M.abscessus_ATCC_1997 -----------------------------------------SIHTGPVAP
Mflv_2178|M.gilvum_PYR-GCK RSGADGEAG----------------------DAGTGGRGGAG--------
MSMEG_0868|M.smegmatis_MC2_155 TAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAY
TH_3810|M.thermoresistible__bu RSGNGVFSG-------------------------GGGTPSAG--------
Mb2548|M.bovis_AF2122/97 IPGGYMQFG----------------PNTGTPITSVTGAPITVLNVQIGGY
Rv2519|M.tuberculosis_H37Rv IPGGYMQFG----------------PNTGTPITSVTGAPITVLNVQIGGY
MMAR_1538|M.marinum_M IPQGYMQFG----------------PNTGTPITSVSGVPITTLDVQFGGY
MUL_2395|M.ulcerans_Agy99 IPQGYMQFG----------------PNTGTPITSVSGVRVH-LEQSERCW
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PAI-----------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 IDLDTATPAQLDLAAKIKALAVPTQQATGIELVSPDGRLIGPLNGYLYNP
MAB_0112|M.abscessus_ATCC_1997 PTVPTPKAP----------------------AVAIATPPAPPVLAPLAPV
Mflv_2178|M.gilvum_PYR-GCK -----------------GSGGKGGISGTG----------------TPGGA
MSMEG_0868|M.smegmatis_MC2_155 DPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQ
TH_3810|M.thermoresistible__bu ------------------FGVPTTIQFPAG---------------SCTSR
Mb2548|M.bovis_AF2122/97 DPNGGYWSLPSIFDSGGNHGTLPAVILGTGQTTGYAPPGTVISISIHDNQ
Rv2519|M.tuberculosis_H37Rv DPNGGYWSLPSIFDSGGNHGTLPAVILGTGQTTGYAPPGTVISISIHDNQ
MMAR_1538|M.marinum_M DPLGTYYPVTSIVDSGGNHGTIPGIILGTGQTSGVVPPGTVISISTNDNQ
MUL_2395|M.ulcerans_Agy99 D---------------------GGIQLPAAVT------GCLRRFSCHDN-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VIGQALFEVGNAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLV
MAB_0112|M.abscessus_ATCC_1997 VPPTPPVVTVKQAEGGRGGDVVVTAGGTKQPEAVTKPIQQFVAAETIAPR
Mflv_2178|M.gilvum_PYR-GCK GQSGQSATGRSGGAGGEG--------GAGGAGGTDD--------------
MSMEG_0868|M.smegmatis_MC2_155 TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
TH_3810|M.thermoresistible__bu AVSREGIMPSSRAASARA--------GAACASSTSRSRRSFCCSRA----
Mb2548|M.bovis_AF2122/97 TLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNY
Rv2519|M.tuberculosis_H37Rv TLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNY
MMAR_1538|M.marinum_M TLLYSYTTTGTDSPVVTGNIPMNTGLLPFALGPVYISNSPSGVGTVVFNY
MUL_2395|M.ulcerans_Agy99 ---------------------------------ARVASTP----TTLRVR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GIPEEAIVSLASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAEAA
MAB_0112|M.abscessus_ATCC_1997 TGYTDYLRLTKTSEIAAVAIPGAAGIAMMTFVGAALGYRQAKAGHTVRAS
Mflv_2178|M.gilvum_PYR-GCK ---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADGTPGTAGTTGANNP---------------
TH_3810|M.thermoresistible__bu ---------------------------------------
Mb2548|M.bovis_AF2122/97 PPP------------------------------------
Rv2519|M.tuberculosis_H37Rv PPP------------------------------------
MMAR_1538|M.marinum_M PPP------------------------------------
MUL_2395|M.ulcerans_Agy99 PQP------------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MAV_1346|M.avium_104 ---------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 FGQAGLVDLVNLASTYLGASALLNVFEVPVPTAALITTS
MAB_0112|M.abscessus_ATCC_1997 AAARFLE--------------------------------