For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQAS AFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGL LYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMS GGAGGTGGATGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEP TVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNG IVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALP GDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS GTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2005 | PE_PGRS35 | - | 100% (558) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | 2e-90 | 61.05% (267) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1002 | PE_PGRS16 | 2e-86 | 43.23% (465) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 5e-29 | 50.67% (150) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1983 | PE_PGRS35 | 0.0 | 99.82% (558) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-14 | 39.42% (104) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 7e-16 | 31.58% (228) | hypothetical protein MAB_0321c |
| M. marinum M | MMAR_2933 | - | 0.0 | 69.53% (558) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 6e-25 | 35.16% (273) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-37 | 40.71% (253) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-16 | 35.24% (227) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4399 | - | 2e-91 | 59.65% (285) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 2e-37 | 40.39% (255) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------MSGTQSAESDDDADDSEGDASADDAEDAEE
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
Mb2005|M.bovis_AF2122/97 --------------------------------------------------
Rv1983|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2933|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 FVGDSGNGGSDDDAADDSEKDVDSSTDDGVGDFEGVVLDDAESEADSQLS
MUL_4399|M.ulcerans_Agy99 --------MSYLLVAPELLTSAATDLEGIASALSTANLAAAVPTTGMLAA
Mb2005|M.bovis_AF2122/97 --------------------------------------------------
Rv1983|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2933|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VPQPASTESTEQSADVANDADGNADPIADAGPEAVTAPVALSGASAPAIP
MUL_4399|M.ulcerans_Agy99 GADEVSAAVASLFAGYGQAYQSISLQANAFQAQFIQAINGAGGAYVAAEA
Mb2005|M.bovis_AF2122/97 -----------------------MS-FLVVVPEFLTSAAADVENIGSTLR
Rv1983|M.tuberculosis_H37Rv -----------------------MS-FLVVVPEFLTSAAADVENIGSTLR
MMAR_2933|M.marinum_M -----------------------MS-LLVVAPEWLTSAAAELQSIESALS
MLBr_01183|M.leprae_Br4923 -----------------------MPLFLNAEPQALTAAANTLEGLSAATV
MAV_1346|M.avium_104 -----------------------MS-FVTTRPEALLAVASMLEGLGSSMD
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DGP-----------------------------------APVEPMGPLINS
MUL_4399|M.ulcerans_Agy99 AS--------------------------------------TSPLQAFEDT
Mb2005|M.bovis_AF2122/97 AAN-----------------------------------------------
Rv1983|M.tuberculosis_H37Rv AAN-----------------------------------------------
MMAR_2933|M.marinum_M AAN-----------------------------------------------
MLBr_01183|M.leprae_Br4923 ASN-----------------------------------------------
MAV_1346|M.avium_104 AQN-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 LWWAVPKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTE
MUL_4399|M.ulcerans_Agy99 VLG------------------------VINAPTQTLLGRPLIGDGAAGTV
Mb2005|M.bovis_AF2122/97 ------------------------------------AAAAASTTALAAAG
Rv1983|M.tuberculosis_H37Rv ------------------------------------AAAAASTTALAAAG
MMAR_2933|M.marinum_M ------------------------------------AAAAVPTTGLAAAA
MLBr_01183|M.leprae_Br4923 ------------------------------------AAAAQLTTEIAPPA
MAV_1346|M.avium_104 ------------------------------------AAAAAPTTSIAPAA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFS------------
MAB_0321c|M.abscessus_ATCC_199 ------------------------------MAN-----------------
Mvan_0928|M.vanbaalenii_PYR-1 QNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAG---------------
MUL_4399|M.ulcerans_Agy99 ANPNGGAGGFLYGNGGNGFSQTTAGVAGGAGGAAG---------------
Mb2005|M.bovis_AF2122/97 ADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQT--------------
Rv1983|M.tuberculosis_H37Rv ADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQT--------------
MMAR_2933|M.marinum_M ADEVSTAVATLFAGFGQEYQAISTQLSAFQQQFALT--------------
MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS--------------
MAV_1346|M.avium_104 ADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQN--------------
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu -------------KLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_0321c|M.abscessus_ATCC_199 -------------IISNGPDGDAGATG--------------AQGSQGAT-
Mvan_0928|M.vanbaalenii_PYR-1 ------------LLWGSGGDGGAGGAG-------------AAGGTGGNAG
MUL_4399|M.ulcerans_Agy99 -------------LIGNGGMGGAGGAG-------------AAGGAGGTGG
Mb2005|M.bovis_AF2122/97 -------------LNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETL
Rv1983|M.tuberculosis_H37Rv -------------LNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETL
MMAR_2933|M.marinum_M -------------LNSSAGSYSAAEAQSVSILDTLGQDVFGAINAPTEAL
MLBr_01183|M.leprae_Br4923 -------------LLTSSSAYAGTETAN----------------------
MAV_1346|M.avium_104 -------------LDTNADSYGATEAANRVNTSAAALQGLAPNVIPNAAP
.
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_0321c|M.abscessus_ATCC_199 -------------------------GAAGAMANCN---------------
Mvan_0928|M.vanbaalenii_PYR-1 LLWG-----------------NGGHGGAGGAGVNG---------------
MUL_4399|M.ulcerans_Agy99 WWFG-----------------NGGVGGAGGAGTAG---------------
Mb2005|M.bovis_AF2122/97 LGRP----------------------LIGDGAPG----------------
Rv1983|M.tuberculosis_H37Rv LGRP----------------------LIGDGAPG----------------
MMAR_2933|M.marinum_M LGRP----------------------LIGNGANG----------------
MLBr_01183|M.leprae_Br4923 ------------------------------HDSL----------------
MAV_1346|M.avium_104 AADP----------------------PPAGTTSLG---------------
Mflv_5091|M.gilvum_PYR-GCK VG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---AAG
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu ------------------------------------------NG----YR
MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------W
Mvan_0928|M.vanbaalenii_PYR-1 -----------------------------------------------AVG
MUL_4399|M.ulcerans_Agy99 -----------------------------------------------AVG
Mb2005|M.bovis_AF2122/97 --------------------------------------------------
Rv1983|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2933|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------------------------------------------T
Mflv_5091|M.gilvum_PYR-GCK TVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG---
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu TTDNNALDGGHG------GNGGN---------------------------
MAB_0321c|M.abscessus_ATCC_199 IDDDCATRGGTG--------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 TSGVNNGRGGDGTAGGSGGAGGNAGLLS----------------------
MUL_4399|M.ulcerans_Agy99 FNGVSGGAGGAG--------------------------------------
Mb2005|M.bovis_AF2122/97 -TATSPNGGAGG--------------------------------------
Rv1983|M.tuberculosis_H37Rv -TATSPNGGAGG--------------------------------------
MMAR_2933|M.marinum_M -TATSPNGGAGG--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 SIGWAQNVGAAA--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG---
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu --VGFFSLFNLG--------------GAGGWGGSGVDG------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------GTGGNGGP----------------
Mvan_0928|M.vanbaalenii_PYR-1 ---GRGGDGGVG--------------GAGGKGGAGAHG------------
MUL_4399|M.ulcerans_Agy99 ---GAAGWWGAG--------------GAGGQGGTG---------------
Mb2005|M.bovis_AF2122/97 -----------------------LLYGNGGNGYSATASG-----------
Rv1983|M.tuberculosis_H37Rv -----------------------LLYGNGGNGYSATASG-----------
MMAR_2933|M.marinum_M -----------------------LLFGNGGIGYSQTGAG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------SDFITLGEGQFAPVPG-----------
Mflv_5091|M.gilvum_PYR-GCK --------------------GAGSTGAVGG-----------VGGKGIQGG
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ------------------------VDVVGG--------------------
MAB_0321c|M.abscessus_ATCC_199 ----------------------------GG--------------------
Mvan_0928|M.vanbaalenii_PYR-1 ------------------------SDAVAAE-------------------
MUL_4399|M.ulcerans_Agy99 -------------------------GMAGG--------------------
Mb2005|M.bovis_AF2122/97 ------------------------VGG-----------------------
Rv1983|M.tuberculosis_H37Rv ------------------------VGG-----------------------
MMAR_2933|M.marinum_M ------------------------IVG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------AAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK QGLQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES
MAB_0321c|M.abscessus_ATCC_199 ---------AGGPGG-------------------------------HGGV
Mvan_0928|M.vanbaalenii_PYR-1 --------EDGGPGG-------------------------------SGGA
MUL_4399|M.ulcerans_Agy99 ---------YDNVNG------------------------------VFGIT
Mb2005|M.bovis_AF2122/97 --------GAGGSAG----------------------------LIGNGGA
Rv1983|M.tuberculosis_H37Rv --------GAGGSAG----------------------------LIGNGGA
MMAR_2933|M.marinum_M --------GAGGSAG----------------------------LIGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------IPNFNPG----------------------------LTAATTA
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNG-------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MAB_0321c|M.abscessus_ATCC_199 IDFEVETFMD----------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GGNAG---------------------------------------------
MUL_4399|M.ulcerans_Agy99 AGNGG---------------------------------------------
Mb2005|M.bovis_AF2122/97 GGAGGPNAPG----------------------------------------
Rv1983|M.tuberculosis_H37Rv GGAGGPNAPG----------------------------------------
MMAR_2933|M.marinum_M GGTGGAGATG----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GPPAPAAPAA----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------ADGGTGGAGGAGGTGG-TGGAGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_0321c|M.abscessus_ATCC_199 --------------------GVTLQAKGGRGGNGG---------------
Mvan_0928|M.vanbaalenii_PYR-1 ----------------AGGVGGRGALLFGRGGDGG---------------
MUL_4399|M.ulcerans_Agy99 ----------------DGGAGGRGGWLFGDAGAGG---------------
Mb2005|M.bovis_AF2122/97 ------------------GAGGNGGWLLGNGGIGG---------------
Rv1983|M.tuberculosis_H37Rv ------------------GAGGNGGWLLGNGGIGG---------------
MMAR_2933|M.marinum_M ------------------GAGGNGGWLFGSGGIGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------AAG--APVLASMGRGPS---------------
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_0321c|M.abscessus_ATCC_199 ------------------------------------HGGAGGTGGTGGKG
Mvan_0928|M.vanbaalenii_PYR-1 --DGGSAGTGGAGGFGGTGGAIVVTLPGGKLSDSDGAGGAGGVGGAAGLG
MUL_4399|M.ulcerans_Agy99 -----QGGLGGDGNYAGQGSYGGVGGAGGAGG----AAGMFGSGGSGGAG
Mb2005|M.bovis_AF2122/97 --------------------------PGGASSIPGMSGGAGGTGGATGLL
Rv1983|M.tuberculosis_H37Rv --------------------------PGGASSIPGMSGGAGGTGGAAGLL
MMAR_2933|M.marinum_M --------------------------TGGANALG--TGGTGGLGGSAGLF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------IGGLSVPPSWAPGGVAPAANATPA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
TH_3810|M.thermoresistible__bu GRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGG
MAB_0321c|M.abscessus_ATCC_199 GDGDDCEFGRTG-------GNGGTGGRGGD------------GNFAGTGG
Mvan_0928|M.vanbaalenii_PYR-1 GDGGGGGLGGLLG------QAGVNGDSGAT---------AAAGNAGGVGG
MUL_4399|M.ulcerans_Agy99 GEGGAFGDGNAGG-----SGSGGHGGNGGNG-----------GWLYGDAG
Mb2005|M.bovis_AF2122/97 GWGANGGAGGLGDGVGVDRGTGGAGGRGGLL-----------YGGYGVSG
Rv1983|M.tuberculosis_H37Rv GWGANGGAGGLGDGVGVDRGTGGAGGRGGLL-----------YGGYGVSG
MMAR_2933|M.marinum_M GGGGNGGAGGLG--ISGDLGTGGAGGTGGFL-----------LGDYGVSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 QLVGAGFTSAAPDTAPVTAVPGGVPSMATAG-----------RGGYGLGA
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
TH_3810|M.thermoresistible__bu DG---------------GNGGSAG--------------------------
MAB_0321c|M.abscessus_ATCC_199 NG------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 AG---------------GLGGRLPIVDLNNASPAQATLAALIKKLGLPIQ
MUL_4399|M.ulcerans_Agy99 AG---------------GQGGNAAP-------------------------
Mb2005|M.bovis_AF2122/97 PG------------------------------------------------
Rv1983|M.tuberculosis_H37Rv PG------------------------------------------------
MMAR_2933|M.marinum_M AG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PR------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
TH_3810|M.thermoresistible__bu -------RGGTGGLRGVFGINGGNG------------------------R
MAB_0321c|M.abscessus_ATCC_199 -----------GAILVKCQHDLSLG------------------------T
Mvan_0928|M.vanbaalenii_PYR-1 AATGIQLEDVDGRLVGPLNAYLYNTIIGKAIFDVGNTFSSASLSARVKEI
MUL_4399|M.ulcerans_Agy99 --------GAYSDNLGTFQSSYTSG------------------------N
Mb2005|M.bovis_AF2122/97 ----------GDGRTVPLEIIHVTEP-----------------------T
Rv1983|M.tuberculosis_H37Rv ----------GDGRTVPLEIIHVTEP-----------------------T
MMAR_2933|M.marinum_M ----------GDGRTVPLEVVNVTEP-----------------------V
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------YGVKPTVMPKPAI---------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
TH_3810|M.thermoresistible__bu AGLGGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGTPSA
MAB_0321c|M.abscessus_ATCC_199 HPMDVSAGTGGNGGIG----------------GGGGGGGSVGANG--ATT
Mvan_0928|M.vanbaalenii_PYR-1 VILSVGGQWGSEYELYAHKLAAQLFG-----IPADAIAALANGQAPVGLS
MUL_4399|M.ulcerans_Agy99 GGAGGNGGVAGMIGTGG--------------AGGAGGAGGVNAFDSGGGG
Mb2005|M.bovis_AF2122/97 VHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYS
Rv1983|M.tuberculosis_H37Rv VHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYS
MMAR_2933|M.marinum_M VNVNVNGGHSTPVLIDTGSAGLVMQVKDVGGPLGLLRMGLPSGISMSAYS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
TH_3810|M.thermoresistible__bu GFGVPTTIQFPAGSCTSRAVSREG------------------------IM
MAB_0321c|M.abscessus_ATCC_199 GVFSSSSDCSGPGPQPNPGSPGDP--------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GNELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLAGTYLGVS
MUL_4399|M.ulcerans_Agy99 G-GGGNGGNGGAGGASGALIEAGG----------------------VGGS
Mb2005|M.bovis_AF2122/97 GGLYYIFATYTTTVDFGNGIVTAP------------------TAVNVVLL
Rv1983|M.tuberculosis_H37Rv GGLYYIFATYTTTVDFGNGIVTAP------------------TAVNVVLL
MMAR_2933|M.marinum_M GGLTYLFATYPTTVDFGNGIVTST------------------TGVDVVLF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
TH_3810|M.thermoresistible__bu PSSRAASARAG---------------------------AACASSTSRSRR
MAB_0321c|M.abscessus_ATCC_199 ---GTSVAVSG------------------------------AQGNPGQAQ
Mvan_0928|M.vanbaalenii_PYR-1 ATLNAFKVRGPESFSAPVLPAAPSPVPASDEYGLGGRLPLIDLDTATPAQ
MUL_4399|M.ulcerans_Agy99 GGGGGAGVVGP------------------------------PAGNPGNDG
Mb2005|M.bovis_AF2122/97 SIPTSPFAISTYFS-----------------------ALLADPTTTPFEA
Rv1983|M.tuberculosis_H37Rv SIPTSPFAISTYFS-----------------------ALLADPTTTPFEA
MMAR_2933|M.marinum_M SIPTSPYALTTWLN-----------------------ALWSNPLTTPFDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
TH_3810|M.thermoresistible__bu SFCCSRA-------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 FLIVP---------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 LDLAAKIKALAVPTQQATGIELVSPDGRLIGPLNGYLYNPVIGQALFEVG
MUL_4399|M.ulcerans_Agy99 LDGVTGASGLLFGG------------------------------------
Mb2005|M.bovis_AF2122/97 YFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGP
Rv1983|M.tuberculosis_H37Rv YFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGP
MMAR_2933|M.marinum_M YFQSAGVDGVLGVGPNAVGPGPSIPTQALGGGLGQGLLIDMKGGELVFGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATG-TTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 QAYD-PAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 NAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLVGIPEEAIVSL
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
Mb2005|M.bovis_AF2122/97 NPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS
Rv1983|M.tuberculosis_H37Rv NPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS
MMAR_2933|M.marinum_M NPL-TPEFSISGAPIATLWVSVNGGAPVAVPSIIDSGGVMGTIPSSVIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAG--AEGGAGGGGGAGGSGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAEAAFGQAGLVDLV
MUL_4399|M.ulcerans_Agy99 --------------------------------------------------
Mb2005|M.bovis_AF2122/97 GTLPANTNIEVYTS-PGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQP
Rv1983|M.tuberculosis_H37Rv GTLPANTNIEVYTS-PGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQP
MMAR_2933|M.marinum_M STLPANTNITVYTDNTMTTEVYHYSTNDYQPTVISSGLMNTGFLPFWNQP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD-
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu -----------------------------
MAB_0321c|M.abscessus_ATCC_199 -----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 NLASTYLGASALLNVFEVPVPTAALITTS
MUL_4399|M.ulcerans_Agy99 -----------------------------
Mb2005|M.bovis_AF2122/97 VYIDYSPSGIGTTVFDHPA----------
Rv1983|M.tuberculosis_H37Rv VYIDYSPSGIGTTVFDHPA----------
MMAR_2933|M.marinum_M VYIDYSPAGTGTTVFDMP-----------
MLBr_01183|M.leprae_Br4923 -----------------------------
MAV_1346|M.avium_104 -----------------------------