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RAEQTVRQRRCRRRSITPTWEVRHGQHLRVCAVRNRAGSQCRPSSTPHNTTFARTHRIEIGALGNDEKRR LSRNHWGYLDETAGDVDNHDRTGVGVAQLSVAPPWLVSAAQDLQSIGSTLAAANGAAAGPTTVLATAAAD EVSTAIAALFAGHAREYHSLSGHFGAFNQQFVQALNSASGAYASAEAQSAPLLQTVGRDVLGAINAPTEF LLARPLIGNGADGTAANPNGGAGGLLIGNGGNGYSQTTPGLTGGTGGTAGLIGNGGSGGAGGPNAAGGPG GLGGWLYGNNGPAGTGSPVNASVPLYLDNNFPAVNVSINGGPSVPVLLDTGSAGLVVPIWDIGLQNLGVP TGFDVIRYGNGVNILYADFNTTVDFGSGAVTAPTSVQVGILPFPTSLQGLTLIAMGNGFGPTGHGVLGIG PNINAATGGHGNVVTTALPGQLNEGELINIPQGYMQFGPNTGTPITSVSGVPITTLDVQFGGYDPLGTYY PVTSIVDSGGNHGTIPGIILGTGQTSGVVPPGTVISISTNDNQTLLYSYTTTGTDSPVVTGNIPMNTGLL PFALGPVYISNSPSGVGTVVFNYPPP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1538 | - | - | 100% (587) | PE family protein, PE26 |
| M. marinum M | MMAR_2933 | - | e-120 | 46.37% (565) | PE-PGRS family protein |
| M. marinum M | MMAR_2272 | - | e-102 | 45.22% (502) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2548 | PE26 | 0.0 | 68.90% (492) | PE family protein |
| M. gilvum PYR-GCK | Mflv_2178 | - | 1e-16 | 53.26% (92) | hypothetical protein Mflv_2178 |
| M. tuberculosis H37Rv | Rv2519 | PE26 | 0.0 | 69.11% (492) | PE family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-11 | 37.50% (88) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 3e-07 | 37.39% (115) | hypothetical protein MAB_0321c |
| M. avium 104 | MAV_1346 | - | 1e-13 | 30.48% (269) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-26 | 30.81% (383) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 4e-09 | 28.08% (317) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2395 | - | 0.0 | 90.74% (378) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 2e-22 | 57.78% (90) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2178|M.gilvum_PYR-GCK MSG--TAHAPGKTRLFANVTVAVGLGGAALG--AAALLAP--QASAAPEE
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPRTVEYEYSLVACDS
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ---MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGNGGSDDDAADD
Mflv_2178|M.gilvum_PYR-GCK WLP----------AGPSSECPPPT-----DGCAN----------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu TLP---------------------------------------------LM
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 SEKDVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPASTESTEQSADVA
Mflv_2178|M.gilvum_PYR-GCK VAAVGGVHGAQGPANLATPQTS---GSPLFRPLFG-------------NG
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu CEAGDSVGGLGGASHDRSAFSASALGMASFG-------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 NDADGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLINSLW
Mflv_2178|M.gilvum_PYR-GCK ADAPADC-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_1538|M.marinum_M ------------------------------------MRAEQTVRQRRCRR
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 WAVPKSG-------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK -----------------------------------------VGNACN---
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu ------------------------------------------PDWNPGGA
MMAR_1538|M.marinum_M RSITPTWEVRHGQHLRVCAVRNRAGSQCRPSSTPHNTTFARTHRIEIGAL
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ---------GRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTE
Mflv_2178|M.gilvum_PYR-GCK ----GRDGGLIWGNGGAGAN-------GGHGGNAGLVGNGGRGGD-----
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL
MAB_0321c|M.abscessus_ATCC_199 --------------------------------MANIISNG----------
TH_4332|M.thermoresistible__bu FLGLIGPGGLLIGDG-------------LNGTDAYIDENG----------
MMAR_1538|M.marinum_M GNDEKRRLSRNHWGYLDETAGDVDNHDRTGVGVAQLSVAP----------
MUL_2395|M.ulcerans_Agy99 --------------------------------MAQLSVAP----------
Mb2548|M.bovis_AF2122/97 --------------------------------MSRLIVAP----------
Rv2519|M.tuberculosis_H37Rv --------------------------------MSRLIVAP----------
MLBr_01183|M.leprae_Br4923 -------------------------------MPLFLNAEP----------
MAV_1346|M.avium_104 -------------------------------MS-FVTTRP----------
Mvan_0928|M.vanbaalenii_PYR-1 QNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLWGSGGDGG-----
:
Mflv_2178|M.gilvum_PYR-GCK -----------------------------ATTPGRSGGHGGNGG------
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
MAB_0321c|M.abscessus_ATCC_199 -------------------------------PDGDAGATG----------
TH_4332|M.thermoresistible__bu -----------------------------VFHEATRGGNGG---------
MMAR_1538|M.marinum_M -----------------------------PWLVSAAQDLQSIGS------
MUL_2395|M.ulcerans_Agy99 -----------------------------PWLVSAAQDLQSIGS------
Mb2548|M.bovis_AF2122/97 -----------------------------DWLASAAAEVQSIGS------
Rv2519|M.tuberculosis_H37Rv -----------------------------DWLASAAAEVQSIGS------
MLBr_01183|M.leprae_Br4923 -----------------------------QALTAAANTLEGLSA------
MAV_1346|M.avium_104 -----------------------------EALLAVASMLEGLGS------
Mvan_0928|M.vanbaalenii_PYR-1 -----------------------------AGGAGAAGGTGGNAG------
.
Mflv_2178|M.gilvum_PYR-GCK ----------------------RLWGNGGDGGNGAPGVLGPAGTAPIPPS
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
MAB_0321c|M.abscessus_ATCC_199 -------------------------AQGSQGATGAAGAMANCN-WIDDDC
TH_4332|M.thermoresistible__bu ----------------------LLWGNGGKGGNGLDAGLYTVPDPDNPGS
MMAR_1538|M.marinum_M -----------------------TLAAANGAAAGPTTVLATAAADEVSTA
MUL_2395|M.ulcerans_Agy99 -----------------------TLAAANGAAAGPTTVLATAAADEVSTA
Mb2548|M.bovis_AF2122/97 -----------------------ALSAANAAAAAPTTLLVAAAEDEVSAA
Rv2519|M.tuberculosis_H37Rv -----------------------ALSAANAAAAAPTTLLVAAAEDEVSAA
MLBr_01183|M.leprae_Br4923 -----------------------ATVASNAAAAQLTTEIAPPAADDVSIL
MAV_1346|M.avium_104 -----------------------SMDAQNAAAAAPTTSIAPAAADEVSAL
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------LLWGNGGHGGAGGAGVNGAVGTSGVNNG
. ..
Mflv_2178|M.gilvum_PYR-GCK SLPAATG----TRGDSPPYG------------------------YGNLVG
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
MAB_0321c|M.abscessus_ATCC_199 ATRGGTG-------------------------------------------
TH_4332|M.thermoresistible__bu TIQMYFEAS-----------------------------------------
MMAR_1538|M.marinum_M IAALFAGHA------------------------------------REYHS
MUL_2395|M.ulcerans_Agy99 IAALFAGHA------------------------------------REYHS
Mb2548|M.bovis_AF2122/97 AAALFANYG------------------------------------REYQT
Rv2519|M.tuberculosis_H37Rv AAALFANYG------------------------------------REYQT
MLBr_01183|M.leprae_Br4923 LAHFFSGHG------------------------------------RQYQA
MAV_1346|M.avium_104 QAAQFSAYG------------------------------------TWYQQ
Mvan_0928|M.vanbaalenii_PYR-1 RGGDGTAGGSGGAGGNAG--------------------------LLSGRG
Mflv_2178|M.gilvum_PYR-GCK GDGGTGADGGRYAFGAN----------------------------WSLDL
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGT
MAB_0321c|M.abscessus_ATCC_199 GTGGNGGPGG----------------------------------------
TH_4332|M.thermoresistible__bu -DGADGGRGG-------------------------------------FLF
MMAR_1538|M.marinum_M LSGHFGAFNQQFVQALN-----------------------------SASG
MUL_2395|M.ulcerans_Agy99 LSGHFGAFNQQFVQALN-----------------------------SASG
Mb2548|M.bovis_AF2122/97 LSVRFASLDQQFAQALN-----------------------------SAAA
Rv2519|M.tuberculosis_H37Rv LSVRFASLDQQFAQALN-----------------------------SAAA
MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLL-----------------------------TSSS
MAV_1346|M.avium_104 VSAQAKAIHQTLVQNLD-----------------------------TNAD
Mvan_0928|M.vanbaalenii_PYR-1 GDGGVGGAGGKGGAGAHG-------------------------SDAVAAE
Mflv_2178|M.gilvum_PYR-GCK PVGGAGGAG-----GWANSIDGSATGGNGGD-------------------
MSMEG_0868|M.smegmatis_MC2_155 GIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGA
MAB_0321c|M.abscessus_ATCC_199 -AGGPGGHG--------GVIDFEVETFMDG--------------------
TH_4332|M.thermoresistible__bu GNGGDGGNG------------GNVGGKNGADP------------------
MMAR_1538|M.marinum_M AYASAEAQSAPLLQTVGRDVLGAINAPTEFLLARPLIGNGADGTAANPNG
MUL_2395|M.ulcerans_Agy99 AYASAEAQSASLLQTVGRDVLGAINAPTEFLLGRPLIGNGADGTAANPNG
Mb2548|M.bovis_AF2122/97 SYQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGTAASPIG
Rv2519|M.tuberculosis_H37Rv SYQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGTAASPIG
MLBr_01183|M.leprae_Br4923 AYAGTETAN-----------------------------------------
MAV_1346|M.avium_104 SYGATEAANRVNTSAAALQGLAPNVIPNAAPAADPPP-------------
Mvan_0928|M.vanbaalenii_PYR-1 EDGGPGGSGGAGGNAGAGGVGGRGALLFGRGGDGGDGGSAGTGGAGGFGG
.
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_1538|M.marinum_M GAGGLLIGNGGNGYSQTTPGLTGGTGGTA-----------GLIGNGGSGG
MUL_2395|M.ulcerans_Agy99 GAGGLLIGNGG------------------------------------SGG
Mb2548|M.bovis_AF2122/97 EPGGILYGDGGNGYSQTTPGAVGGAGGSA-----------GFIGNGGAAG
Rv2519|M.tuberculosis_H37Rv EPGGILYGDGGNGYSQTTPGAVGGAGGSA-----------GFIGNGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------AG
Mvan_0928|M.vanbaalenii_PYR-1 TGGAIVVTLPGGKLSDSDGAG----------------------GAGGVGG
Mflv_2178|M.gilvum_PYR-GCK -GGNGAFGGRGGNGG-------------------------------AGG-
MSMEG_0868|M.smegmatis_MC2_155 HGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGN
MAB_0321c|M.abscessus_ATCC_199 -VTLQAKGGRGGNGG-----------------------------------
TH_4332|M.thermoresistible__bu -VTATVAADKSVAGG-----------------------------------
MMAR_1538|M.marinum_M AGGPNAAGGPGGLGG-----------------------------------
MUL_2395|M.ulcerans_Agy99 ARGPNAAGGPGGLGG-----------------------------------
Mb2548|M.bovis_AF2122/97 AGGPGAGGGTGGLGG-----------------------------------
Rv2519|M.tuberculosis_H37Rv AGGPGAGGGTGGLGG-----------------------------------
MLBr_01183|M.leprae_Br4923 HDSL----------------------------------------------
MAV_1346|M.avium_104 TTSLGTSIGWAQNVG-----------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 AAGLGGDGGGGGLGG-----------------------------------
Mflv_2178|M.gilvum_PYR-GCK -----------------SAYGRGGITTGGNGGAGG---------------
MSMEG_0868|M.smegmatis_MC2_155 GGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGT
MAB_0321c|M.abscessus_ATCC_199 --------------------------HGGAGGTGG---------------
TH_4332|M.thermoresistible__bu --------------------------NGGNGGRGG---------------
MMAR_1538|M.marinum_M ----------------------WLYGNNGPAGTGS---------------
MUL_2395|M.ulcerans_Agy99 ----------------------WLYGNNGPAGTGS---------------
Mb2548|M.bovis_AF2122/97 ----------------------WLWGNNGAAGTGD---------------
Rv2519|M.tuberculosis_H37Rv ----------------------WLWGNNGAAGTGD---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------------AAASDFITLGEGQ---------------
Mvan_0928|M.vanbaalenii_PYR-1 -------LLGQAGVNGDSGATAAAGNAGGVGGAGGLGGRLPIVDLNNASP
Mflv_2178|M.gilvum_PYR-GCK -----------------HGSTGAAGGRGGDGA-SAS----------GGYA
MSMEG_0868|M.smegmatis_MC2_155 TIDKGKAAGGNGGDGGFNGTGGATGGRGGDGA-GASVWKANGQHSTGQTD
MAB_0321c|M.abscessus_ATCC_199 -----------------------TGGKGGDGD-DCEFG-----------R
TH_4332|M.thermoresistible__bu -------------------LLFGLGGNGGNGG-WSTTS--------YLDA
MMAR_1538|M.marinum_M -----------------PVNASVPLYLDNNFP-AVNVSINGGPSVPVLLD
MUL_2395|M.ulcerans_Agy99 -----------------PVNASVPLYLDNNFP-AVNVSINGGPSVPVLLD
Mb2548|M.bovis_AF2122/97 -----------------PVNVAVPLRVENNFP-LVNLLVNRGPTVPILLD
Rv2519|M.tuberculosis_H37Rv -----------------PVNVAVPLRVENNFP-LVNLLVNRGPTVPILLD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------FAPVPGAAGIPNFNP-GLTAATTAGPPAPAAPA
Mvan_0928|M.vanbaalenii_PYR-1 AQATLAALIKKLGLPIQAATGIQLEDVDGRLVGPLNAYLYNTIIGKAIFD
Mflv_2178|M.gilvum_PYR-GCK VGGNGGDGGRGG----AGATG------------GTGGTGGAGGDGGRGG-
MSMEG_0868|M.smegmatis_MC2_155 TGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGD
MAB_0321c|M.abscessus_ATCC_199 TGGNGGTGGRGG-------------------------DGNFAGTGGNGGA
TH_4332|M.thermoresistible__bu RGGNGGNGGLGGVLRPGGLLS----------------LLLPSGAASEPGG
MMAR_1538|M.marinum_M TGSAGLVVPIWDIGLQNLGVPTGFDVIRYGNGVNILYADFNTTVDFGSGA
MUL_2395|M.ulcerans_Agy99 IGSAGLVVPIWDIGLQDLGLPTGFDVIRYGNGVNILYADFNTTVDFGSGA
Mb2548|M.bovis_AF2122/97 TGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVDFGGGA
Rv2519|M.tuberculosis_H37Rv TGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVDFGGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AAAGAPVLASMGRGPSIG------------------------------GL
Mvan_0928|M.vanbaalenii_PYR-1 VGNTFSSASLSARVKEIVILSVGGQWGSEYELYAHKLAAQLFGIPADAIA
Mflv_2178|M.gilvum_PYR-GCK -LLGGHGGKG----GNAGLGGNGGTGG-----------------------
MSMEG_0868|M.smegmatis_MC2_155 GALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAG
MAB_0321c|M.abscessus_ATCC_199 ILVKCQHDLS---LGTHPMDVSAGTGG-----------------------
TH_4332|M.thermoresistible__bu LFTGGNGGNGGLAIANHWVGITDGVPGPDDD-------------------
MMAR_1538|M.marinum_M VTAPTSVQVGILPFPTSLQGLTLIAMGN----------------------
MUL_2395|M.ulcerans_Agy99 VTAPTSVQVGILPFPTSLQGLTLIAMGN----------------------
Mb2548|M.bovis_AF2122/97 ATTPTSVHVGILPYPRNLDSLVLIASGG----------------------
Rv2519|M.tuberculosis_H37Rv ATTPTSVHVGILPYPRNLDSLVLIASGG----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 SVPPSWAPGGVAPAANATPAQLVGAGFT----------------------
Mvan_0928|M.vanbaalenii_PYR-1 ALANGQAPVGLSGNELLAAQFVQELVSTRRVS------------------
Mflv_2178|M.gilvum_PYR-GCK -------------TGGVGGDGGVG--------------------------
MSMEG_0868|M.smegmatis_MC2_155 RIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSN
MAB_0321c|M.abscessus_ATCC_199 -------------NGGIGGGGGGG--------------------------
TH_4332|M.thermoresistible__bu ----------AVSSSAYGGHGGHG--------------------------
MMAR_1538|M.marinum_M -------------GFGPTGHGVLG--------------------------
MUL_2395|M.ulcerans_Agy99 -------------GFGPTGHGVLG--------------------------
Mb2548|M.bovis_AF2122/97 -------------AFGPNGNGILG--------------------------
Rv2519|M.tuberculosis_H37Rv -------------AFGPNGNGILG--------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------SAAPDTAPVTA--------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ---------DALFEAAEAAFGQTG--------------------------
Mflv_2178|M.gilvum_PYR-GCK ------------GGILTATG------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2178|M.gilvum_PYR-GCK --------------------------VVGAGGSGG---AGGTGGRGGD--
MSMEG_0868|M.smegmatis_MC2_155 SGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGV
MAB_0321c|M.abscessus_ATCC_199 ---------------------------------------GSVGANGAT--
TH_4332|M.thermoresistible__bu -------------------------------------AGPGSGGNGGS--
MMAR_1538|M.marinum_M -----------------------------IGPNIN-AATGGHGNVVTTAL
MUL_2395|M.ulcerans_Agy99 -----------------------------IGPNIN-VAAGGHGNVVTTAL
Mb2548|M.bovis_AF2122/97 -----------------------------IGPNVGSYAVSGPGNVVTTDL
Rv2519|M.tuberculosis_H37Rv -----------------------------IGPNVGSYAVSGPGNVVTTDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------VPGGVPSMATAGRGGYGLGAP
Mvan_0928|M.vanbaalenii_PYR-1 ----------------VVDMVNLAGTYLGVSATLNAFKVRGPESFSAPVL
Mflv_2178|M.gilvum_PYR-GCK ------------------GGDGGQAG------------------------
MSMEG_0868|M.smegmatis_MC2_155 VNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_1538|M.marinum_M PG------------------------------------------------
MUL_2395|M.ulcerans_Agy99 PG------------------------------------------------
Mb2548|M.bovis_AF2122/97 PG------------------------------------------------
Rv2519|M.tuberculosis_H37Rv PG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 RY------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 PAAPSPVPASDEYG------------------------------------
Mflv_2178|M.gilvum_PYR-GCK ------------------------------------------RGGAGGLA
MSMEG_0868|M.smegmatis_MC2_155 NATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAA
MAB_0321c|M.abscessus_ATCC_199 ---------------------------------------------TGVFS
TH_4332|M.thermoresistible__bu -------------------------------------------AVANSLG
MMAR_1538|M.marinum_M ------------------------------------------QLNEGELI
MUL_2395|M.ulcerans_Agy99 ------------------------------------------QLNEGELI
Mb2548|M.bovis_AF2122/97 ------------------------------------------QLNEGTLI
Rv2519|M.tuberculosis_H37Rv ------------------------------------------QLNEGTLI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------GVKPTVMP
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------LGGRLPLIDLDTATPAQLDLAAKIKALA
Mflv_2178|M.gilvum_PYR-GCK GRSGADGEAG----------------------DAGTGGRGGAG-------
MSMEG_0868|M.smegmatis_MC2_155 TTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQA
MAB_0321c|M.abscessus_ATCC_199 SSSDCS----------------------------GPGPQPNPG-------
TH_4332|M.thermoresistible__bu NAIAGNGG------------------------DAGRFVLIGPG-------
MMAR_1538|M.marinum_M NIPQGYMQFG---------------------PNTGTPITSVSG-------
MUL_2395|M.ulcerans_Agy99 NIPQGYMQFG---------------------PNTGTPITSVSG-------
Mb2548|M.bovis_AF2122/97 DIPGGYMQFG---------------------PNTGTPITSVTG-------
Rv2519|M.tuberculosis_H37Rv DIPGGYMQFG---------------------PNTGTPITSVTG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 KPAI----------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VPTQQATGIELVSPDGRLIG-----------PLNGYLYNPVIGQALFEVG
Mflv_2178|M.gilvum_PYR-GCK ------------------GSGGKGGISGTG----------------TPGG
MSMEG_0868|M.smegmatis_MC2_155 YDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGG
MAB_0321c|M.abscessus_ATCC_199 -------------------SPGDPGTSVAV-----------------SGA
TH_4332|M.thermoresistible__bu ------------------GNGGNGGTGLXX----------------XPRP
MMAR_1538|M.marinum_M --------VPITTLDVQFGGYDPLGTYYPVTSIVDSGGNHGTIPGIILGT
MUL_2395|M.ulcerans_Agy99 --------VRVH-LEQSERCWD---------------------GGIQLPA
Mb2548|M.bovis_AF2122/97 --------APITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGT
Rv2519|M.tuberculosis_H37Rv --------APITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 NAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLVGIPEEAIVSL
Mflv_2178|M.gilvum_PYR-GCK AGQSGQSATGRSGGAGGEG--------GAGGAGGTDD-------------
MSMEG_0868|M.smegmatis_MC2_155 QTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGG
MAB_0321c|M.abscessus_ATCC_199 QGNPGQAQFLIVP-------------------------------------
TH_4332|M.thermoresistible__bu RRRRNHRRTRRRPNGRRPRPPPGR--------------------------
MMAR_1538|M.marinum_M GQTSGVVPPGTVISISTNDNQTLLYSYTTTGTDSPVVTGNIPMNTGLLPF
MUL_2395|M.ulcerans_Agy99 AVT------GCLRRFSCHDN------------------------------
Mb2548|M.bovis_AF2122/97 GQTTGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLNTGLTPF
Rv2519|M.tuberculosis_H37Rv GQTTGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLNTGLTPF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAEAAFGQAGLVDLV
Mflv_2178|M.gilvum_PYR-GCK -----------------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGADGTPGTAGTTGANNP----
MAB_0321c|M.abscessus_ATCC_199 -----------------------------
TH_4332|M.thermoresistible__bu -----------------------------
MMAR_1538|M.marinum_M ALGPVYISNSPSGVGTVVFNYPPP-----
MUL_2395|M.ulcerans_Agy99 ----ARVASTP----TTLRVRPQP-----
Mb2548|M.bovis_AF2122/97 LLGPVYISNNPSGVGTVVFNYPPP-----
Rv2519|M.tuberculosis_H37Rv LLGPVYISNNPSGVGTVVFNYPPP-----
MLBr_01183|M.leprae_Br4923 -----------------------------
MAV_1346|M.avium_104 -----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 NLASTYLGASALLNVFEVPVPTAALITTS