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M. bovis AF2122 / 97 Mb2622 (PE_PGRS44)

annotation: PE-PGRS family protein
coordinates: 2888999 - 2890639
length: 546

MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAA
AFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGIL
YGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTG
GAGGAGGDAPLIGWGGNGGPGGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGL
FLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGG
SGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGSIGGFA
VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGDGGNAGNGAMP
ANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGANGANGPS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2622PE_PGRS44-100% (546)PE-PGRS family protein
M. bovis AF2122 / 97Mb0857cPE_PGRS14e-15054.23% (568) PE-PGRS family protein
M. bovis AF2122 / 97Mb1121PE_PGRS22e-14753.64% (591) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-6e-8443.75% (464) triple helix repeat-containing collagen
M. tuberculosis H37RvRv2591PE_PGRS440.099.08% (546) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1134.78% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-5e-4635.75% (442) hypothetical protein MAB_4284c
M. marinum MMMAR_2113-0.064.00% (550) PE-PGRS family protein
M. avium 104MAV_1346-2e-2334.85% (264) PE family protein
M. smegmatis MC2 155MSMEG_0868-3e-8441.73% (520) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-3938.53% (340) PUTATIVE -
M. ulcerans Agy99MUL_1718-1e-14956.86% (503) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-4e-8440.87% (575) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG
Rv2591|M.tuberculosis_H37Rv         -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG
MMAR_2113|M.marinum_M               -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG
MUL_1718|M.ulcerans_Agy99           -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199      AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923          ------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPA
MAV_1346|M.avium_104                ------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAA
                                                                                      

Mb2622|M.bovis_AF2122/97            ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA
Rv2591|M.tuberculosis_H37Rv         ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA
MMAR_2113|M.marinum_M               ADDVSQAIAALLSSHGAQYQALSAQAAQFHQGFMQLLNSAGGAYAGAEAA
MUL_1718|M.ulcerans_Agy99           ADDVSQAFAALLSSHGAQYQALSAQAAQFHQGLMQLLNSAGGAYAGAEAA
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199      PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923          ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETA
MAV_1346|M.avium_104                ADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAA
                                     :  .                                   . .       

Mb2622|M.bovis_AF2122/97            NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG---------------
Rv2591|M.tuberculosis_H37Rv         NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG---------------
MMAR_2113|M.marinum_M               NVSPLQTLESNVLGALNTPTQAIFGRPLIGDGANG---------------
MUL_1718|M.ulcerans_Agy99           NVSPLQTLESNVVGALNTPTQAIFGRPLIGDGANG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG
MLBr_01183|M.leprae_Br4923          N------------------------------HDSL---------------
MAV_1346|M.avium_104                NRVNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLG--------------
                                                                                      

Mb2622|M.bovis_AF2122/97            ---TAASPNGGDGGILY---------------------------------
Rv2591|M.tuberculosis_H37Rv         ---TAASPNGGDGGILY---------------------------------
MMAR_2113|M.marinum_M               ---TATSPNGGAGGFLY---------------------------------
MUL_1718|M.ulcerans_Agy99           ---TATSPNGGAGGFLY---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199      QGSTAVNGDVRDSNIIN---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------GNGGNG
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------GNGGNG
MMAR_2113|M.marinum_M               --------------------------------------------GNGGNG
MUL_1718|M.ulcerans_Agy99           --------------------------------------------GNGGNG
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------ADHGSNVGVD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------TSIGWA
                                                                                      

Mb2622|M.bovis_AF2122/97            FSQTTAG-------------------VAGGAGG-----------------
Rv2591|M.tuberculosis_H37Rv         FSQTTAG-------------------VAGGAGG-----------------
MMAR_2113|M.marinum_M               YSFTSGGT------------------QSGGTGG-----------------
MUL_1718|M.ulcerans_Agy99           YSFTSGGT------------------QSGGTGG-----------------
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199      QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                QNVGAAAS------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2113|M.marinum_M               --------------------------------------------------
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      ---------VDVVGGNP---------------------------------
MAB_4284c|M.abscessus_ATCC_199      TTNINDSFNTDRSTNIGSGNTTNTEIGSHN--------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            ----------------------------------------------SAGL
Rv2591|M.tuberculosis_H37Rv         ----------------------------------------------SAGL
MMAR_2113|M.marinum_M               ----------------------------------------------SAGL
MUL_1718|M.ulcerans_Agy99           ----------------------------------------------SAGL
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      ---------DGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199      -------QANIGTS------------------------------TSAGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ----------------------------------------------DFIT
                                                                                      

Mb2622|M.bovis_AF2122/97            IGNGGNGGAGGAGA------------------------------------
Rv2591|M.tuberculosis_H37Rv         IGNGGNGGAGGAGA------------------------------------
MMAR_2113|M.marinum_M               IGNGGNGGNGFLGG------------------------------------
MUL_1718|M.ulcerans_Agy99           IGNGGNGGNGFLGG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AAVGGNAGLAGNAG------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                LGEGQFAPVPGAAG------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            -------------AGGAGGAGGWLLGNGGAGGPGG---------------
Rv2591|M.tuberculosis_H37Rv         -------------AGGAGGAGGWLLGNGGAGGPGG---------------
MMAR_2113|M.marinum_M               -------------AGGAAGSGGWLAGSGGNGGAGG---------------
MUL_1718|M.ulcerans_Agy99           -------------AGGAAGSGGWLAGSGGNGGAGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      -------------LAGNAGLAGNAGLAGNAGLAGN---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ----------------IPNFNPGLTAATTAGPPAP---------------
                                                                                      

Mb2622|M.bovis_AF2122/97            -PTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFA--AFGNGGAGGNGGAS
Rv2591|M.tuberculosis_H37Rv         -PTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFA--AFGNGGAGGNGGAS
MMAR_2113|M.marinum_M               -SVTGVGEVGGAGGAGGSAPLLGWGGNGGAGGDS--TQGAGGMGGAGGAG
MUL_1718|M.ulcerans_Agy99           -SVTGVGEVGGAGGAGGSAPLLGWGGNGGAGGDS--TQGTGGRGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu      -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ---AAPAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGVAPAANATPAQLV
                                                                                      

Mb2622|M.bovis_AF2122/97            G--SLFGVGGAG-------GVGGSSEDV--------------GGTGGAGG
Rv2591|M.tuberculosis_H37Rv         G--SLFGVGGAG-------GVGGSSEDV--------------GGTGGAGG
MMAR_2113|M.marinum_M               G--ALASIGGAG-------GAGGTGTTS--------------GGDGGVGG
MUL_1718|M.ulcerans_Agy99           G--ALAAIGGAG-------GAGGTGATA--------------GGDGGVGG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
TH_3810|M.thermoresistible__bu      GRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGG
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                GAGFTSAAPDTAP---------------------------VTAVPGGVPS
                                                                                      

Mb2622|M.bovis_AF2122/97            AG-------------RGLFLGLGG--------------------------
Rv2591|M.tuberculosis_H37Rv         AG-------------RGLFLGLGG--------------------------
MMAR_2113|M.marinum_M               EG-------------SGRLFGLGG--------------------------
MUL_1718|M.ulcerans_Agy99           EG-------------SGRLFGLGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1       AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155      AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
TH_3810|M.thermoresistible__bu      DG---------------GNGGSAG--------------------------
MAB_4284c|M.abscessus_ATCC_199      AG-------------LAGNAGLAG--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                MA-------------TAGRGGYG---------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            -------DGGAGGTSNNNGGDGGAG------------------------G
Rv2591|M.tuberculosis_H37Rv         -------DGGAGGTSNNNGGDGGAG------------------------G
MMAR_2113|M.marinum_M               -------AGGAGGTGITSGGVGGDG------------------------G
MUL_1718|M.ulcerans_Agy99           -------AGGAGGTGTTSGGVGG---------------------------
Mflv_5091|M.gilvum_PYR-GCK          -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1       -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155      SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
TH_3810|M.thermoresistible__bu      -------RGGTGGLRGVFGINGGNG------------------------R
MAB_4284c|M.abscessus_ATCC_199      -------NAAVAGNAAVAGNAAVAG------------------------N
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ------LGAPRYGVKPTVMPKPAI--------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            TAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDSSALIG
Rv2591|M.tuberculosis_H37Rv         TAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDSSALIG
MMAR_2113|M.marinum_M               AGGGLLFGLGGSGGAGGVATDA----------TGIGGTGGAGGESGVIIG
MUL_1718|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155      GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
TH_3810|M.thermoresistible__bu      AGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTPSA
MAB_4284c|M.abscessus_ATCC_199      AAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGGSTAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            YAQGGSGGLGGFGESTGGDGGLGG---------------------AGAVL
Rv2591|M.tuberculosis_H37Rv         YAQGGSGGLGGFGESTGGDGGLGG---------------------AGAVL
MMAR_2113|M.marinum_M               YAQSGAGGIGGYGGDIGGTGGAGG---------------------VAGVL
MUL_1718|M.ulcerans_Agy99           ------------------TGGAGG---------------------VAGVL
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155      GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
TH_3810|M.thermoresistible__bu      GFGVPTTIQFPAGSCTSRAVSREG------------------------IM
MAB_4284c|M.abscessus_ATCC_199      GGGAHTGVGGGVSTGVGVGSHVGG--------------------GISESL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            IGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLIGLGAG
Rv2591|M.tuberculosis_H37Rv         IGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLIGLGAG
MMAR_2113|M.marinum_M               VGAGVGGFGGMGG-AGTTGGAGGVG-------------GQGVTLTGLGVG
MUL_1718|M.ulcerans_Agy99           VGAGVGGFGGMGG-AGTTGGAGDVG-------------GQGVTLTGLGVG
Mflv_5091|M.gilvum_PYR-GCK          GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1       GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155      GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
TH_3810|M.thermoresistible__bu      PSSRAASARAG---------------------------AACASSTSRSRR
MAB_4284c|M.abscessus_ATCC_199      GGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGGISE
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            GGGSIG-------------------GFAVNVGNGVGGLGGQGGQGAALIG
Rv2591|M.tuberculosis_H37Rv         GGGGIG-------------------GFAVNVGNGVGGLGGQGGQGAALIG
MMAR_2113|M.marinum_M               GIGGVG-------------------GFGTATG----GDGGAGGQGAALWG
MUL_1718|M.ulcerans_Agy99           GIGGVG-------------------GFGTATG----GDGGAGGQGAALWG
Mflv_5091|M.gilvum_PYR-GCK          AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1       SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155      AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
TH_3810|M.thermoresistible__bu      SFCCSRA-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVGGGIS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            LGAGGAGGAG---GATVVGLGGNDGDGGDGGGLFSIGVGGDGG-------
Rv2591|M.tuberculosis_H37Rv         LGAGGAGGAG---GATVVGLGGNGGDGGDGGGLFSIGVGGDGG-------
MMAR_2113|M.marinum_M               AGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG-------
MUL_1718|M.ulcerans_Agy99           AGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG-------
Mflv_5091|M.gilvum_PYR-GCK          GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1       GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155      QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            ----NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTG
Rv2591|M.tuberculosis_H37Rv         ----NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNG---
MMAR_2113|M.marinum_M               ----NGGNAGATGGNGGNGGNIGVVANGTFTQTLFGDGGNGGNGGTGGTP
MUL_1718|M.ulcerans_Agy99           ----NGGNAGATGGNG---GNIGVVANGTFTQTLFGDGGNGGNGGNGGTG
Mflv_5091|M.gilvum_PYR-GCK          ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1       ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155      GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb2622|M.bovis_AF2122/97            ---GTGGSGGILFGANGANGPS-----
Rv2591|M.tuberculosis_H37Rv         ---GTGGSGGILFGANGANGPS-----
MMAR_2113|M.marinum_M               GTGGTGGSGGILIGADGTNGS------
MUL_1718|M.ulcerans_Agy99           GTPGTGGSGGILIGADGTNGS------
Mflv_5091|M.gilvum_PYR-GCK          -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ---------------------------
MAB_4284c|M.abscessus_ATCC_199      EAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923          ---------------------------
MAV_1346|M.avium_104                ---------------------------