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MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAA AFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGIL YGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTG GAGGAGGDAPLIGWGGNGGPGGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGL FLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGG SGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGSIGGFA VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGDGGNAGNGAMP ANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGANGANGPS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | - | 100% (546) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb0857c | PE_PGRS14 | e-150 | 54.23% (568) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | e-147 | 53.64% (591) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 6e-84 | 43.75% (464) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 0.0 | 99.08% (546) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 1e-11 | 34.78% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 5e-46 | 35.75% (442) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2113 | - | 0.0 | 64.00% (550) | PE-PGRS family protein |
M. avium 104 | MAV_1346 | - | 2e-23 | 34.85% (264) | PE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-84 | 41.73% (520) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-39 | 38.53% (340) | PUTATIVE - |
M. ulcerans Agy99 | MUL_1718 | - | 1e-149 | 56.86% (503) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-84 | 40.87% (575) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG Rv2591|M.tuberculosis_H37Rv -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG MMAR_2113|M.marinum_M -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG MUL_1718|M.ulcerans_Agy99 -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ MLBr_01183|M.leprae_Br4923 ------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPA MAV_1346|M.avium_104 ------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAA Mb2622|M.bovis_AF2122/97 ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA Rv2591|M.tuberculosis_H37Rv ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA MMAR_2113|M.marinum_M ADDVSQAIAALLSSHGAQYQALSAQAAQFHQGFMQLLNSAGGAYAGAEAA MUL_1718|M.ulcerans_Agy99 ADDVSQAFAALLSSHGAQYQALSAQAAQFHQGLMQLLNSAGGAYAGAEAA Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETA MAV_1346|M.avium_104 ADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAA : . . . Mb2622|M.bovis_AF2122/97 NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG--------------- Rv2591|M.tuberculosis_H37Rv NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG--------------- MMAR_2113|M.marinum_M NVSPLQTLESNVLGALNTPTQAIFGRPLIGDGANG--------------- MUL_1718|M.ulcerans_Agy99 NVSPLQTLESNVVGALNTPTQAIFGRPLIGDGANG--------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG MLBr_01183|M.leprae_Br4923 N------------------------------HDSL--------------- MAV_1346|M.avium_104 NRVNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLG-------------- Mb2622|M.bovis_AF2122/97 ---TAASPNGGDGGILY--------------------------------- Rv2591|M.tuberculosis_H37Rv ---TAASPNGGDGGILY--------------------------------- MMAR_2113|M.marinum_M ---TATSPNGGAGGFLY--------------------------------- MUL_1718|M.ulcerans_Agy99 ---TATSPNGGAGGFLY--------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG--------------------------------- MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 --------------------------------------------GNGGNG Rv2591|M.tuberculosis_H37Rv --------------------------------------------GNGGNG MMAR_2113|M.marinum_M --------------------------------------------GNGGNG MUL_1718|M.ulcerans_Agy99 --------------------------------------------GNGGNG Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------ADHGSNVGVD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 --------------------------------------------TSIGWA Mb2622|M.bovis_AF2122/97 FSQTTAG-------------------VAGGAGG----------------- Rv2591|M.tuberculosis_H37Rv FSQTTAG-------------------VAGGAGG----------------- MMAR_2113|M.marinum_M YSFTSGGT------------------QSGGTGG----------------- MUL_1718|M.ulcerans_Agy99 YSFTSGGT------------------QSGGTGG----------------- Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ- Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------ MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 QNVGAAAS------------------------------------------ Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA TH_3810|M.thermoresistible__bu ---------VDVVGGNP--------------------------------- MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTNTEIGSHN-------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 ----------------------------------------------SAGL Rv2591|M.tuberculosis_H37Rv ----------------------------------------------SAGL MMAR_2113|M.marinum_M ----------------------------------------------SAGL MUL_1718|M.ulcerans_Agy99 ----------------------------------------------SAGL Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV TH_3810|M.thermoresistible__bu ---------DGGTPG------------------------------AHGES MAB_4284c|M.abscessus_ATCC_199 -------QANIGTS------------------------------TSAGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ----------------------------------------------DFIT Mb2622|M.bovis_AF2122/97 IGNGGNGGAGGAGA------------------------------------ Rv2591|M.tuberculosis_H37Rv IGNGGNGGAGGAGA------------------------------------ MMAR_2113|M.marinum_M IGNGGNGGNGFLGG------------------------------------ MUL_1718|M.ulcerans_Agy99 IGNGGNGGNGFLGG------------------------------------ Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD----------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN----------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP TH_3810|M.thermoresistible__bu HTPGVYTDRQ---------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AAVGGNAGLAGNAG------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 LGEGQFAPVPGAAG------------------------------------ Mb2622|M.bovis_AF2122/97 -------------AGGAGGAGGWLLGNGGAGGPGG--------------- Rv2591|M.tuberculosis_H37Rv -------------AGGAGGAGGWLLGNGGAGGPGG--------------- MMAR_2113|M.marinum_M -------------AGGAAGSGGWLAGSGGNGGAGG--------------- MUL_1718|M.ulcerans_Agy99 -------------AGGAAGSGGWLAGSGGNGGAGG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGN--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ----------------IPNFNPGLTAATTAGPPAP--------------- Mb2622|M.bovis_AF2122/97 -PTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFA--AFGNGGAGGNGGAS Rv2591|M.tuberculosis_H37Rv -PTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFA--AFGNGGAGGNGGAS MMAR_2113|M.marinum_M -SVTGVGEVGGAGGAGGSAPLLGWGGNGGAGGDS--TQGAGGMGGAGGAG MUL_1718|M.ulcerans_Agy99 -SVTGVGEVGGAGGAGGSAPLLGWGGNGGAGGDS--TQGTGGRGGAGGAG Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAGLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ---AAPAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGVAPAANATPAQLV Mb2622|M.bovis_AF2122/97 G--SLFGVGGAG-------GVGGSSEDV--------------GGTGGAGG Rv2591|M.tuberculosis_H37Rv G--SLFGVGGAG-------GVGGSSEDV--------------GGTGGAGG MMAR_2113|M.marinum_M G--ALASIGGAG-------GAGGTGTTS--------------GGDGGVGG MUL_1718|M.ulcerans_Agy99 G--ALAAIGGAG-------GAGGTGATA--------------GGDGGVGG Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG TH_3810|M.thermoresistible__bu GRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGG MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGLAGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 GAGFTSAAPDTAP---------------------------VTAVPGGVPS Mb2622|M.bovis_AF2122/97 AG-------------RGLFLGLGG-------------------------- Rv2591|M.tuberculosis_H37Rv AG-------------RGLFLGLGG-------------------------- MMAR_2113|M.marinum_M EG-------------SGRLFGLGG-------------------------- MUL_1718|M.ulcerans_Agy99 EG-------------SGRLFGLGG-------------------------- Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------- Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------- MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG TH_3810|M.thermoresistible__bu DG---------------GNGGSAG-------------------------- MAB_4284c|M.abscessus_ATCC_199 AG-------------LAGNAGLAG-------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 MA-------------TAGRGGYG--------------------------- Mb2622|M.bovis_AF2122/97 -------DGGAGGTSNNNGGDGGAG------------------------G Rv2591|M.tuberculosis_H37Rv -------DGGAGGTSNNNGGDGGAG------------------------G MMAR_2113|M.marinum_M -------AGGAGGTGITSGGVGGDG------------------------G MUL_1718|M.ulcerans_Agy99 -------AGGAGGTGTTSGGVGG--------------------------- Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH TH_3810|M.thermoresistible__bu -------RGGTGGLRGVFGINGGNG------------------------R MAB_4284c|M.abscessus_ATCC_199 -------NAAVAGNAAVAGNAAVAG------------------------N MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ------LGAPRYGVKPTVMPKPAI-------------------------- Mb2622|M.bovis_AF2122/97 TAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDSSALIG Rv2591|M.tuberculosis_H37Rv TAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDSSALIG MMAR_2113|M.marinum_M AGGGLLFGLGGSGGAGGVATDA----------TGIGGTGGAGGESGVIIG MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD TH_3810|M.thermoresistible__bu AGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTPSA MAB_4284c|M.abscessus_ATCC_199 AAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGGSTAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 YAQGGSGGLGGFGESTGGDGGLGG---------------------AGAVL Rv2591|M.tuberculosis_H37Rv YAQGGSGGLGGFGESTGGDGGLGG---------------------AGAVL MMAR_2113|M.marinum_M YAQSGAGGIGGYGGDIGGTGGAGG---------------------VAGVL MUL_1718|M.ulcerans_Agy99 ------------------TGGAGG---------------------VAGVL Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL TH_3810|M.thermoresistible__bu GFGVPTTIQFPAGSCTSRAVSREG------------------------IM MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVSTGVGVGSHVGG--------------------GISESL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 IGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLIGLGAG Rv2591|M.tuberculosis_H37Rv IGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLIGLGAG MMAR_2113|M.marinum_M VGAGVGGFGGMGG-AGTTGGAGGVG-------------GQGVTLTGLGVG MUL_1718|M.ulcerans_Agy99 VGAGVGGFGGMGG-AGTTGGAGDVG-------------GQGVTLTGLGVG Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG TH_3810|M.thermoresistible__bu PSSRAASARAG---------------------------AACASSTSRSRR MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGGISE MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 GGGSIG-------------------GFAVNVGNGVGGLGGQGGQGAALIG Rv2591|M.tuberculosis_H37Rv GGGGIG-------------------GFAVNVGNGVGGLGGQGGQGAALIG MMAR_2113|M.marinum_M GIGGVG-------------------GFGTATG----GDGGAGGQGAALWG MUL_1718|M.ulcerans_Agy99 GIGGVG-------------------GFGTATG----GDGGAGGQGAALWG Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV TH_3810|M.thermoresistible__bu SFCCSRA------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVGGGIS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 LGAGGAGGAG---GATVVGLGGNDGDGGDGGGLFSIGVGGDGG------- Rv2591|M.tuberculosis_H37Rv LGAGGAGGAG---GATVVGLGGNGGDGGDGGGLFSIGVGGDGG------- MMAR_2113|M.marinum_M AGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG------- MUL_1718|M.ulcerans_Agy99 AGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG------- Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------- Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------- MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 ----NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTG Rv2591|M.tuberculosis_H37Rv ----NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNG--- MMAR_2113|M.marinum_M ----NGGNAGATGGNGGNGGNIGVVANGTFTQTLFGDGGNGGNGGTGGTP MUL_1718|M.ulcerans_Agy99 ----NGGNAGATGGNG---GNIGVVANGTFTQTLFGDGGNGGNGGNGGTG Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG- Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG- MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 ---GTGGSGGILFGANGANGPS----- Rv2591|M.tuberculosis_H37Rv ---GTGGSGGILFGANGANGPS----- MMAR_2113|M.marinum_M GTGGTGGSGGILIGADGTNGS------ MUL_1718|M.ulcerans_Agy99 GTPGTGGSGGILIGADGTNGS------ Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu --------------------------- MAB_4284c|M.abscessus_ATCC_199 EAQGHAQGHASETAHTTLPGAEHH--- MLBr_01183|M.leprae_Br4923 --------------------------- MAV_1346|M.avium_104 ---------------------------