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VSRLIVAPDWLASAAAEVQSIGSALSAANAAAAAPTTLLVAAAEDEVSAAAAALFANYGREYQTLSVRFA SLDQQFAQALNSAAASYQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGTAASPIGEPGGI LYGDGGNGYSQTTPGAVGGAGGSAGFIGNGGAGGAGGPGAGGGTGGLGGWLWGNNGAAGTGDPVNVAVPL RVENNFPLVNLLVNRGPTVPILLDTGSSSLVIPFWKIGWQNLGLPTGFDVVHYGNGVSIVYADVPTTVDF GGGAATTPTSVHVGILPYPRNLDSLVLIASGGAFGPNGNGILGIGPNVGSYAVSGPGNVVTTDLPGQLNE GTLIDIPGGYMQFGPNTGTPITSVTGAPITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGTGQ TTGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNYP PP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2519 | PE26 | - | 100% (492) | PE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1983 | PE_PGRS35 | 3e-69 | 65.17% (201) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 3e-65 | 39.20% (449) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2548 | PE26 | 0.0 | 99.80% (492) | PE family protein |
| M. gilvum PYR-GCK | Mflv_2178 | - | 3e-15 | 48.89% (90) | hypothetical protein Mflv_2178 |
| M. leprae Br4923 | MLBr_01183 | - | 4e-08 | 34.52% (84) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 2e-07 | 40.00% (90) | hypothetical protein MAB_0321c |
| M. marinum M | MMAR_1538 | - | 0.0 | 69.11% (492) | PE family protein, PE26 |
| M. avium 104 | MAV_1346 | - | 1e-14 | 30.60% (232) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-22 | 47.01% (117) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-10 | 30.16% (189) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2395 | - | 1e-133 | 62.53% (379) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 1e-23 | 56.19% (105) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -------------MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGN
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_2178|M.gilvum_PYR-GCK -------------------------MSGTAHAPGKTRLFANVTVAVGLGG
TH_3810|M.thermoresistible__bu -------------------------VDGDGGSGGRTGLFSKLSRGGDGGD
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GGSDDDAADDSEKDVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPAST
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mflv_2178|M.gilvum_PYR-GCK AALGAAALLAPQASAAPEEWLPAGPSSECPPPTDGCANVAAVGGVHGAQG
TH_3810|M.thermoresistible__bu GGLGGNGGHG---------------------GGTGIISLLSLAG------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ESTEQSADVANDADGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVE
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mflv_2178|M.gilvum_PYR-GCK PAN--------------------------------------------LAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M -------------------------------------MRAEQTVRQRRCR
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 PMG------------------------------------------PLINS
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mflv_2178|M.gilvum_PYR-GCK PQTSGSPLFRPLFGNG-------------------------ADAPADCVG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M RRSITPTWEVRHGQHLRVCAVRNRAGSQCRPSSTPHNTTFARTHRIEIGA
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 LWWAVPKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTE
MAB_0321c|M.abscessus_ATCC_199 --------------------------------MANIISNGPDG-------
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL
Mflv_2178|M.gilvum_PYR-GCK NACNGRDGGLIWGNGGAGAN-------GGHGGNAGLVGNGGRGG------
TH_3810|M.thermoresistible__bu ---NGGNGGNGYRTTDNNALDGGHGGNGGNVGFFSLFNLGGAGG------
Rv2519|M.tuberculosis_H37Rv ---------------------------------MSRLIVAPDWLA-----
Mb2548|M.bovis_AF2122/97 ---------------------------------MSRLIVAPDWLA-----
MMAR_1538|M.marinum_M LGNDEKRRLSRNHWGYLDETAGDVDNHDRTGVGVAQLSVAPPWLV-----
MUL_2395|M.ulcerans_Agy99 ---------------------------------MAQLSVAPPWLV-----
MLBr_01183|M.leprae_Br4923 --------------------------------MPLFLNAEPQALT-----
MAV_1346|M.avium_104 --------------------------------MS-FVTTRPEALL-----
Mvan_0928|M.vanbaalenii_PYR-1 QNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLWGSGGDGGAG---
.
MAB_0321c|M.abscessus_ATCC_199 ------------------DAGATGAQGS----------------------
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
Mflv_2178|M.gilvum_PYR-GCK ------------DATTPGRSGGHGGNGGRLWGNGG---------------
TH_3810|M.thermoresistible__bu -------------------WGGSGVDGVDVVGGNP---------------
Rv2519|M.tuberculosis_H37Rv -------------------SAAAEVQSIG---------------------
Mb2548|M.bovis_AF2122/97 -------------------SAAAEVQSIG---------------------
MMAR_1538|M.marinum_M -------------------SAAQDLQSIG---------------------
MUL_2395|M.ulcerans_Agy99 -------------------SAAQDLQSIG---------------------
MLBr_01183|M.leprae_Br4923 -------------------AAANTLEGLS---------------------
MAV_1346|M.avium_104 -------------------AVASMLEGLG---------------------
Mvan_0928|M.vanbaalenii_PYR-1 ---------------GAGAAGGTGGNAGLLWGNGGHG-------------
. :.
MAB_0321c|M.abscessus_ATCC_199 ---------------QGATGAAGAMANCN---------------WIDDDC
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
Mflv_2178|M.gilvum_PYR-GCK ---------------DGGNGAPGVLGPAG--------TAPIPPSSLPAAT
TH_3810|M.thermoresistible__bu --------------DGGTPGAHGESHTPG---------------VYTDRQ
Rv2519|M.tuberculosis_H37Rv ---------------SALSAANAAAAAPT--------------TLLVAAA
Mb2548|M.bovis_AF2122/97 ---------------SALSAANAAAAAPT--------------TLLVAAA
MMAR_1538|M.marinum_M ---------------STLAAANGAAAGPT--------------TVLATAA
MUL_2395|M.ulcerans_Agy99 ---------------STLAAANGAAAGPT--------------TVLATAA
MLBr_01183|M.leprae_Br4923 ---------------AATVASNAAAAQLT--------------TEIAPPA
MAV_1346|M.avium_104 ---------------SSMDAQNAAAAAPT--------------TSIAPAA
Mvan_0928|M.vanbaalenii_PYR-1 --------------GAGGAGVNGAVGTSG-------------VNNGRGGD
. .
MAB_0321c|M.abscessus_ATCC_199 ATRGGTGGTGGNGG------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
Mflv_2178|M.gilvum_PYR-GCK GTRGDSP-PYGYGN------------------------------------
TH_3810|M.thermoresistible__bu GEDGEDGTGTGIGG------------------------------------
Rv2519|M.tuberculosis_H37Rv EDEVSAAAAALFAN------------------------------------
Mb2548|M.bovis_AF2122/97 EDEVSAAAAALFAN------------------------------------
MMAR_1538|M.marinum_M ADEVSTAIAALFAG------------------------------------
MUL_2395|M.ulcerans_Agy99 ADEVSTAIAALFAG------------------------------------
MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSG------------------------------------
MAV_1346|M.avium_104 ADEVSALQAAQFSA------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GTAGGSGGAGGNAG------------------------------------
.
MAB_0321c|M.abscessus_ATCC_199 -------------PGGAGGPGGHGGVIDFEVETFMDG-------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGT
Mflv_2178|M.gilvum_PYR-GCK ------------LVGGDGGTGADGGRYAFGANWSLDLP------------
TH_3810|M.thermoresistible__bu -------------RGGNGGSSSGTHPMAEDGEHVKALD------------
Rv2519|M.tuberculosis_H37Rv --------------YGREYQTLSVRFASLDQQFAQALN------------
Mb2548|M.bovis_AF2122/97 --------------YGREYQTLSVRFASLDQQFAQALN------------
MMAR_1538|M.marinum_M --------------HAREYHSLSGHFGAFNQQFVQALN------------
MUL_2395|M.ulcerans_Agy99 --------------HAREYHSLSGHFGAFNQQFVQALN------------
MLBr_01183|M.leprae_Br4923 --------------HGRQYQAHASQGATNHQDLIQSLL------------
MAV_1346|M.avium_104 --------------YGTWYQQVSAQAKAIHQTLVQNLD------------
Mvan_0928|M.vanbaalenii_PYR-1 ------LLSGRGGDGGVGGAGGKGGAGAHGSDAVAAEE------------
.
MAB_0321c|M.abscessus_ATCC_199 -------------------VTLQAKGGRGG--------------------
MSMEG_0868|M.smegmatis_MC2_155 GIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGA
Mflv_2178|M.gilvum_PYR-GCK -------------------VGGAGGAGGWANSIDG---------------
TH_3810|M.thermoresistible__bu --------------------GRPGLDGGNG--------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAG
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 HGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGN
Mflv_2178|M.gilvum_PYR-GCK --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv --------------------------------------------------
Mb2548|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1538|M.marinum_M --------------------------------------------------
MUL_2395|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 -----------------------------NGGHGG---------------
MSMEG_0868|M.smegmatis_MC2_155 GGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGT
Mflv_2178|M.gilvum_PYR-GCK ---------------------------SATGGNGG---------------
TH_3810|M.thermoresistible__bu ----------------------------SHGGNGG---------------
Rv2519|M.tuberculosis_H37Rv ------------------------------SAAAS---------------
Mb2548|M.bovis_AF2122/97 ------------------------------SAAAS---------------
MMAR_1538|M.marinum_M ------------------------------SASGA---------------
MUL_2395|M.ulcerans_Agy99 ------------------------------SASGA---------------
MLBr_01183|M.leprae_Br4923 ------------------------------TSSSA---------------
MAV_1346|M.avium_104 ------------------------------TNADS---------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------DGGPGGSGG---------------
.
MAB_0321c|M.abscessus_ATCC_199 -------AGGTGG----------TGGKGGD--------------------
MSMEG_0868|M.smegmatis_MC2_155 TIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDT
Mflv_2178|M.gilvum_PYR-GCK -------DGGNGA----------FGGRGGNG-------------------
TH_3810|M.thermoresistible__bu -------HGGRGG----------FLGIGGSG-------------------
Rv2519|M.tuberculosis_H37Rv -------YQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGT
Mb2548|M.bovis_AF2122/97 -------YQTAEATGASLVQTATQGVLGVINAPTEFMFGRSLIGDGADGT
MMAR_1538|M.marinum_M -------YASAEAQSAPLLQTVGRDVLGAINAPTEFLLARPLIGNGADGT
MUL_2395|M.ulcerans_Agy99 -------YASAEAQSASLLQTVGRDVLGAINAPTEFLLGRPLIGNGADGT
MLBr_01183|M.leprae_Br4923 -------YAGTETAN-----------------------------------
MAV_1346|M.avium_104 -------YGATEAANRVNTSAAALQGLAPNVIPNAAPAADPPP-------
Mvan_0928|M.vanbaalenii_PYR-1 -------AGGNAGAGGVGGRGALLFGRGGDG-------------------
MAB_0321c|M.abscessus_ATCC_199 -------GDDCEFG---------------------RTGGNGGTGGRGGDG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDG
Mflv_2178|M.gilvum_PYR-GCK ------GAGGSAYGRGG-----------------ITTGGNGGAGGHGSTG
TH_3810|M.thermoresistible__bu -------GWGGHGGNGG------------------DTDADGGNGGDGGNG
Rv2519|M.tuberculosis_H37Rv AASPIGEPGGILYGDGGNGYSQTTPGAVGGAGGSAGFIGNGGAGGAGGPG
Mb2548|M.bovis_AF2122/97 AASPIGEPGGILYGDGGNGYSQTTPGAVGGAGGSAGFIGNGGAAGAGGPG
MMAR_1538|M.marinum_M AANPNGGAGGLLIGNGGNGYSQTTPGLTGGTGGTAGLIGNGGSGGAGGPN
MUL_2395|M.ulcerans_Agy99 AANPNGGAGGLLIGNGG-------------------------SGGARGPN
MLBr_01183|M.leprae_Br4923 ---------------------------------------------HDSL-
MAV_1346|M.avium_104 -------------------------------------------AGTTSLG
Mvan_0928|M.vanbaalenii_PYR-1 -------GDGGSAGTGGAGGFGGTGGAIVVTLPGGKLSDSDGAGGAGGVG
.
MAB_0321c|M.abscessus_ATCC_199 NFAGTGGNG------------------GAILVKCQHD-------------
MSMEG_0868|M.smegmatis_MC2_155 ALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGR
Mflv_2178|M.gilvum_PYR-GCK AAGGRGGDG--------------ASASGGYAVGGNGG-------------
TH_3810|M.thermoresistible__bu GSAGRGGTG------------------------GLRG-------------
Rv2519|M.tuberculosis_H37Rv AGGGTGGLGG--------------------WLWGNNGAAGTGDPVNVAVP
Mb2548|M.bovis_AF2122/97 AGGGTGGLGG--------------------WLWGNNGAAGTGDPVNVAVP
MMAR_1538|M.marinum_M AAGGPGGLGG--------------------WLYGNNGPAGTGSPVNASVP
MUL_2395|M.ulcerans_Agy99 AAGGPGGLGG--------------------WLYGNNGPAGTGSPVNASVP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 TSIGWAQNVG--------------------AAASDFITLGEGQFAPVPGA
Mvan_0928|M.vanbaalenii_PYR-1 GAAGLGGDGG---------------------GGGLGGLLGQAGVNGDSGA
MAB_0321c|M.abscessus_ATCC_199 --LSLGTHPMDVSAGTGGNGG-----------------------------
MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNA
Mflv_2178|M.gilvum_PYR-GCK ---DGGRGGAGATGGTGGTGG-----------------------------
TH_3810|M.thermoresistible__bu ---VFGINGGNGRAGLGGRGX-----------------------------
Rv2519|M.tuberculosis_H37Rv LRVENNFPLVNLLVNRGPTVP-----------------------------
Mb2548|M.bovis_AF2122/97 LRVENNFPLVNLLVNRGPTVP-----------------------------
MMAR_1538|M.marinum_M LYLDNNFPAVNVSINGGPSVP-----------------------------
MUL_2395|M.ulcerans_Agy99 LYLDNNFPAVNVSINGGPSVP-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AGIPNFNPGLTAATTAGPPAP-----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 TAAAGNAGGVGGAGGLGGRLPIVDLNNASPAQATLAALIKKLGLPIQAAT
MAB_0321c|M.abscessus_ATCC_199 ----IGGGGGGGGSVGANGAT-----------------------------
MSMEG_0868|M.smegmatis_MC2_155 SGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGS
Mflv_2178|M.gilvum_PYR-GCK ----AGGDGGRGGLLGGHGGK-----------------------------
TH_3810|M.thermoresistible__bu ----XXXGGGVGAAVRSG--------------------------------
Rv2519|M.tuberculosis_H37Rv ----ILLDTGSSSLVIPFWKIG----------------------------
Mb2548|M.bovis_AF2122/97 ----ILLDTGSSSLVIPFWKIG----------------------------
MMAR_1538|M.marinum_M ----VLLDTGSAGLVVPIWDIG----------------------------
MUL_2395|M.ulcerans_Agy99 ----VLLDIGSAGLVVPIWDIG----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----AAPAAAAGAPVLASMGRG----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GIQLEDVDGRLVGPLNAYLYNTIIG---------------KAIFDVGNTF
MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------------TGVF
MSMEG_0868|M.smegmatis_MC2_155 GINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVV
Mflv_2178|M.gilvum_PYR-GCK ----------------------------------------------GGNA
TH_3810|M.thermoresistible__bu ----------------------------------------------NGVF
Rv2519|M.tuberculosis_H37Rv -------------WQNLGLPTGFDVVHYGNGVSIVYADVPTTVDFGGGAA
Mb2548|M.bovis_AF2122/97 -------------WQNLGLPTGFDVVHYGNGVSIVYADVPTTVDFGGGAA
MMAR_1538|M.marinum_M -------------LQNLGVPTGFDVIRYGNGVNILYADFNTTVDFGSGAV
MUL_2395|M.ulcerans_Agy99 -------------LQDLGLPTGFDVIRYGNGVNILYADFNTTVDFGSGAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------PSIG------------------------------GLS
Mvan_0928|M.vanbaalenii_PYR-1 SSASLSARVKEIVILSVGGQWGSEYELYAHKLAAQLFGIPADAIAALANG
MAB_0321c|M.abscessus_ATCC_199 SSSSDCSGPGPQPNPGSPGDPG----------------------------
MSMEG_0868|M.smegmatis_MC2_155 NTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGN
Mflv_2178|M.gilvum_PYR-GCK GLGGNGGTGGTGGVGGDGGVGG--------------------------GI
TH_3810|M.thermoresistible__bu SGGGGTPSAGFGVPTTIQFPAG---------------------------S
Rv2519|M.tuberculosis_H37Rv TTPTSVHVGILPYPRNLDSLVLIASGG--------------------AFG
Mb2548|M.bovis_AF2122/97 TTPTSVHVGILPYPRNLDSLVLIASGG--------------------AFG
MMAR_1538|M.marinum_M TAPTSVQVGILPFPTSLQGLTLIAMGN--------------------GFG
MUL_2395|M.ulcerans_Agy99 TAPTSVQVGILPFPTSLQGLTLIAMGN--------------------GFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 VPPSWAPGGVAPAANATPAQLVGAGFT--------------------SAA
Mvan_0928|M.vanbaalenii_PYR-1 QAPVGLSGNELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLA
MAB_0321c|M.abscessus_ATCC_199 -TSVAVSG---------AQGNPGQAQFLIVP-------------------
MSMEG_0868|M.smegmatis_MC2_155 ATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAAT
Mflv_2178|M.gilvum_PYR-GCK LTATGVVG---------AGGSGGAGGTGGRGGDGGDGGQAGRGGAGGLAG
TH_3810|M.thermoresistible__bu CTSRAVSR----------EGIMPSSRAASARAGAACASSTSRSRRSFCCS
Rv2519|M.tuberculosis_H37Rv PNGNGILGIGPNVGSYAVSGPGNVVTTDLPGQLNEGTLIDIPGGYMQFGP
Mb2548|M.bovis_AF2122/97 PNGNGILGIGPNVGSYAVSGPGNVVTTDLPGQLNEGTLIDIPGGYMQFGP
MMAR_1538|M.marinum_M PTGHGVLGIGPNIN-AATGGHGNVVTTALPGQLNEGELINIPQGYMQFGP
MUL_2395|M.ulcerans_Agy99 PTGHGVLGIGPNIN-VAAGGHGNVVTTALPGQLNEGELINIPQGYMQFGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PDTAPVTAVPGGVPSMATAGRGGYGLGAPRYGVKPTVMPKPAI-------
Mvan_0928|M.vanbaalenii_PYR-1 GTYLGVSATLNAFKVRGPESFSAPVLPAAPSPVPASDEYGLGGRLPLIDL
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAY
Mflv_2178|M.gilvum_PYR-GCK RSGADGEAG----------------------DAGTGGRGGAG--------
TH_3810|M.thermoresistible__bu RA------------------------------------------------
Rv2519|M.tuberculosis_H37Rv NTGTP--------------------------ITSVTGAPITVLNVQIGGY
Mb2548|M.bovis_AF2122/97 NTGTP--------------------------ITSVTGAPITVLNVQIGGY
MMAR_1538|M.marinum_M NTGTP--------------------------ITSVSGVPITTLDVQFGGY
MUL_2395|M.ulcerans_Agy99 NTGTP--------------------------ITSVSGVRVH-LEQSERCW
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DTATPAQLDLAAKIKALAVPTQQATGIELVSPDGRLIGPLNGYLYNPVIG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQ
Mflv_2178|M.gilvum_PYR-GCK -----------------GSGGKGGISGTG---------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv DPNGGYWSLPSIFDSGGNHGTLPAVILGTGQTTGYAPPGTVISISIHDNQ
Mb2548|M.bovis_AF2122/97 DPNGGYWSLPSIFDSGGNHGTLPAVILGTGQTTGYAPPGTVISISIHDNQ
MMAR_1538|M.marinum_M DPLGTYYPVTSIVDSGGNHGTIPGIILGTGQTSGVVPPGTVISISTNDNQ
MUL_2395|M.ulcerans_Agy99 D---------------------GGIQLPAAVT------GCLRRFSCHDN-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 QALFEVGNAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLVGIP
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
Mflv_2178|M.gilvum_PYR-GCK ---------------------TPGGAGQSGQSATGRSG-------GAGGE
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2519|M.tuberculosis_H37Rv TLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNY
Mb2548|M.bovis_AF2122/97 TLLYQYTTTASNSPVVTADPRLNTGLTPFLLGPVYISNNPSGVGTVVFNY
MMAR_1538|M.marinum_M TLLYSYTTTGTDSPVVTGNIPMNTGLLPFALGPVYISNSPSGVGTVVFNY
MUL_2395|M.ulcerans_Agy99 ---------------------------------ARVASTP----TTLRVR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 EEAIVSLASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAEAAFGQ
MAB_0321c|M.abscessus_ATCC_199 ------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADGTPGTAGTTGANNP------------
Mflv_2178|M.gilvum_PYR-GCK GGAGGAGGTDD-------------------------
TH_3810|M.thermoresistible__bu ------------------------------------
Rv2519|M.tuberculosis_H37Rv PPP---------------------------------
Mb2548|M.bovis_AF2122/97 PPP---------------------------------
MMAR_1538|M.marinum_M PPP---------------------------------
MUL_2395|M.ulcerans_Agy99 PQP---------------------------------
MLBr_01183|M.leprae_Br4923 ------------------------------------
MAV_1346|M.avium_104 ------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 AGLVDLVNLASTYLGASALLNVFEVPVPTAALITTS