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M. abscessus ATCC 19977 MAB_0112 (-)

annotation: hypothetical protein MAB_0112
coordinates: 112307 - 113848
length: 513

MLFAVGRHRANPSRRSQQLKRASARAAVVTVLSSGTLMGGFGVFAITTPAADAKPGGGSGNDHDHDHGLG
GALHKLTGGLLGGGGGGNGGPGSGGARNAPSAPSFGKSLHGGSGSEGAAGGNGDSAKSDKDKDKGPGASV
PKPGSAGSTGKTADSAAGSAGSGTGTPGANSSAPGGSNGSSGGGIGGVGTTVGTTLPHSGGAAGVHTPTA
EGAAATESSAGTGTHTEEHPSLKGALGSVAGALAPKTETATTPKTETATSPHTSTAPGATAETPTAGTTH
PEHESSAEEPKVPGVTVNMGGRTIIIWKKKPSTSTHTPGAGTGTNPGHESEGDRDHVINLPGFPALGGAT
NPDAPFGGAAGTRTPGGNPSIHTGPVAPPTVPTPKAPAVAIATPPAPPVLAPLAPVVPPTPPVVTVKQAE
GGRGGDVVVTAGGTKQPEAVTKPIQQFVAAETIAPRTGYTDYLRLTKTSEIAAVAIPGAAGIAMMTFVGA
ALGYRQAKAGHTVRASAAARFLE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0112--100% (513)hypothetical protein MAB_0112
M. abscessus ATCC 19977MAB_0010c-3e-1329.80% (198) hypothetical protein MAB_0010c
M. abscessus ATCC 19977MAB_1280c-1e-1132.85% (207) hypothetical protein MAB_1280c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3537PE_PGRS534e-2528.80% (441) PE-PGRS family protein
M. gilvum PYR-GCKMflv_3843-7e-2129.11% (371) hypothetical protein Mflv_3843
M. tuberculosis H37RvRv3507PE_PGRS532e-2429.25% (424) PE-PGRS family protein
M. leprae Br4923MLBr_01828PPE7e-0540.58% (69) PPE-family protein
M. marinum MMMAR_3303-2e-2432.54% (335) PE-PGRS family protein
M. avium 104MAV_4827-5e-1334.13% (167) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_6433-1e-2329.43% (384) hypothetical protein MSMEG_6433
M. thermoresistible (build 8)TH_3810-6e-0933.16% (196) PUTATIVE -
M. ulcerans Agy99MUL_4280-3e-1736.32% (190) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_5676-1e-1928.85% (357) hypothetical protein Mvan_5676

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            -------------------------------------------MSFVLVS
Rv3507|M.tuberculosis_H37Rv         -------------------------------------------MSFVLVS
MUL_4280|M.ulcerans_Agy99           -------------------------------------------MSYVMAV
MMAR_3303|M.marinum_M               ------------------------------------------MSAFVYAA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR
MAV_4827|M.avium_104                -------------------------------MNIVLGVSMAPSSIQMVVL
MLBr_01828|M.leprae_Br4923          -----------------------------------------MSAPIWMAS
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            PETVAAVATDLKRIGASLAHENASAAASTTAVVSAAADEVSTAVAALFSQ
Rv3507|M.tuberculosis_H37Rv         PETVAAVATDLKRIGASLAHENASAAASTTAVVSAAADEVSTAVAALFSQ
MUL_4280|M.ulcerans_Agy99           PEIIEAAAS-------------TAAASQTAQTVAAAEDEVSAAIATVLSS
MMAR_3303|M.marinum_M               PEELAAASSSLSSLGSSIREAHAASAGLTTSIAAAAEDEVSAAVAKLFGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      ------------------------------------MLFAVGRHRANPSR
Mflv_3843|M.gilvum_PYR-GCK          PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV
MAV_4827|M.avium_104                EGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQL
MLBr_01828|M.leprae_Br4923          PPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMADELVALLVVVPVSS
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            HAQGYQAAAAQVAAFHSRFVQALTAGAGAYAFAEAANASPLQSAMGAVS-
Rv3507|M.tuberculosis_H37Rv         HAQGYQAAAAQVAAFHSRFVQALTAGAGAYAFAEAANASPLQSAMGAVS-
MUL_4280|M.ulcerans_Agy99           HGQGYQVLSARALEFHTRLAQALSAGAGAYSGAEASSAG----LLAAVN-
MMAR_3303|M.marinum_M               YAQQFQALGAQASLFHDQFVQALNGGGFLYAATEAASASPLQAAAAAAVG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      RSQQLKRASARAAVVTVLSSGTLMGGFGVFAITTP---------------
Mflv_3843|M.gilvum_PYR-GCK          TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP
MAV_4827|M.avium_104                SSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGY
MLBr_01828|M.leprae_Br4923          WDGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAYITTLAMMPT
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            ------ASAQTLLSRPLIGNGANATT-PGGNGGDGGWLFGSGGNGAPG--
Rv3507|M.tuberculosis_H37Rv         ------ASAQTLLSRPLIGNGANATT-PGGNGGDGGWLFGSGGNGAPG--
MUL_4280|M.ulcerans_Agy99           ------EPIAALTGRPLIGNGANGTPGLGTDGAPGGWLIGNDGAGGSG--
MMAR_3303|M.marinum_M               VQDAINAPFLQFTGRPLVGPGTDGAPGTGQAGGPGGWLWGDGGDGGSGTP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      ----------AADAKPGGGSGNDHDHDHGLGGALHKLTGG----------
Mflv_3843|M.gilvum_PYR-GCK          VPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGGA
MAV_4827|M.avium_104                ERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVA
MLBr_01828|M.leprae_Br4923          LAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMG----
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      -MRSRVRVAASACLVTSGLFMAGLGGALAFANPDAGS-------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------MASGLLVGGWTTATASADTDTGT-------------
Mb3537|M.bovis_AF2122/97            -----AAGQSGGNGGSAGLWGNGGAGGAGGSGGAAGGNGGNGGWLFGAGG
Rv3507|M.tuberculosis_H37Rv         -----AAGQSGGNGGSAGLWGNGGAGGAGGSGGAAGGNGGNGGWLFGAGG
MUL_4280|M.ulcerans_Agy99           -----AAGSAGGAGGAAGLIGAGGAGGAGGAGGSSTG-------------
MMAR_3303|M.marinum_M               GTATSPAGGAGGAGGSAFLFGSGGHGGSGGTAYAGSG-------------
TH_3810|M.thermoresistible__bu      ------VDGDGGSGGRTGLFSKLSRGGDGGDG------------------
MAB_0112|M.abscessus_ATCC_1997      -----LLGGGGGGNGGPGSGGARNAPSAPSFGKSLHG-------------
Mflv_3843|M.gilvum_PYR-GCK          VLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAG-------------
MAV_4827|M.avium_104                GLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS-------------
MLBr_01828|M.leprae_Br4923          -----TYQEVSTVVVDSAPEAIAAPQIMASDALEASS-------------
                                                    .                                 

MSMEG_6433|M.smegmatis_MC2_155      -------------------------------------------DTAGQGP
Mvan_5676|M.vanbaalenii_PYR-1       -------------------------------------------AANADAT
Mb3537|M.bovis_AF2122/97            TGGIGGTGAPGAMGGTGGNGGNGALLIGGGGLGGAGGMGGTGGGTGGTGG
Rv3507|M.tuberculosis_H37Rv         TGGIGGTGAPGAMGGTGGNGGNGALLIGGGGLGGAGGMGGTGGGTGGTGG
MUL_4280|M.ulcerans_Agy99           -------------------------------------------GAGGTGG
MMAR_3303|M.marinum_M               -------------------------------------------AVGGTGG
TH_3810|M.thermoresistible__bu      -------------------------------------------GLGGNGG
MAB_0112|M.abscessus_ATCC_1997      -------------------------------------------GSGSEGA
Mflv_3843|M.gilvum_PYR-GCK          ---------------------------VALPPAPPGAPGAPVFGEAGAAP
MAV_4827|M.avium_104                -----------------------------------------VAEEPETAL
MLBr_01828|M.leprae_Br4923          ------------------------------------------DQPSPTAP
                                                                                    . 

MSMEG_6433|M.smegmatis_MC2_155      AG--------------------------ADSGAPQVAGPRGTHGQR----
Mvan_5676|M.vanbaalenii_PYR-1       GGGA------------------------DDRARPDTAAAAGGGTDRD---
Mb3537|M.bovis_AF2122/97            NGGNGALLIGAGGVGGAGGIGGQGTGAGGAAGAGGTGGNGGAGGLFMNGG
Rv3507|M.tuberculosis_H37Rv         NGGNGALLIGAGGVGGAGGIGGQGTGAGGAAGAGGTGGNGGAGGLFMNGG
MUL_4280|M.ulcerans_Agy99           AGGAGEWLFGPGGVGGAG---------GSSSSAGGAGGVGGAGGLFG---
MMAR_3303|M.marinum_M               NGGAGGLIFGGGGAGGVGGLG----AAGSATAAPGMGGHGGAGGTSY---
TH_3810|M.thermoresistible__bu      HGGGTGIIS--------------------LLSLAGNGGNGGNG-------
MAB_0112|M.abscessus_ATCC_1997      AGGN------------------------GDSAKSDKDKDKGPGASVP---
Mflv_3843|M.gilvum_PYR-GCK          SGAAAPVAPAAGSGGAG-----------GAGGGSGIGGPGGGGAPVEGTG
MAV_4827|M.avium_104                ARGAALAAANAP-------------LFASSTAALAYAQDPGTGAVDQYSL
MLBr_01828|M.leprae_Br4923          SQSP------------------------QVQNWLQWLQKIGYTDFYN---
                                                                            *         

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            DGGAGGQGGDGAAGDAAASAGGTGGKGGQGGDGGTGGAGGAGPVLFGHGG
Rv3507|M.tuberculosis_H37Rv         DGGAGGQGGDGAAGDAAASAGGTGGKGGQGGDGGTGGAGGAGPVLFGHGG
MUL_4280|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3303|M.marinum_M               --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          GAVPAGAPLAAAGG------------------------------------
MAV_4827|M.avium_104                P-------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            AGGMGGQGGTGGMGGAGGDGTTVIAAGTGGEGGTG---------------
Rv3507|M.tuberculosis_H37Rv         AGGMGGQGGTGGMGGAGGDGTTVIAAGTGGEGGTGGAAGAGGAAGARGAL
MUL_4280|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3303|M.marinum_M               --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            ---------------GTGGTGGNGADAAAVVGFGANGDPGFAGGKGGNGG
Rv3507|M.tuberculosis_H37Rv         TSGGLAGGVGAGGTGGTGGTGGNGADAAAVVGFGANGDPGFAGGKGGNGG
MUL_4280|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3303|M.marinum_M               --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            IGGAAVTGGVAGDGGTGGKGGTGGAGGAGNDAGSTGNPGGKGGDGGIGGA
Rv3507|M.tuberculosis_H37Rv         IGGAAVTGGVAGDGGTGGKGGTGGAGGAGNDAGSTGNPGGKGGDGGIGGA
MUL_4280|M.ulcerans_Agy99           --------------------------------------------GGLGGA
MMAR_3303|M.marinum_M               ------------------------------------------QLGGAAGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------EVPPPAPPIPGA
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            GGAGGAAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVNGADNTLNPDTPG
Rv3507|M.tuberculosis_H37Rv         GGAGGAAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVNGADNTLNPDTPG
MUL_4280|M.ulcerans_Agy99           GGAG----------------------------------------------
MMAR_3303|M.marinum_M               GGAGGQGGLGYDAAADPMAAAG----------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          PVIGEAGVVPPPAPPAPAPPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPP
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            GAGEPGGAGGAGGAGGAAGGPGGTGGTGGNGGN-----------------
Rv3507|M.tuberculosis_H37Rv         GAGEPGGAGGAGGAGGAAGGPGGTGGTGGNGGNGGNGGNGGNGGNGGNGG
MUL_4280|M.ulcerans_Agy99           -VSASGGAGGAGGAGGALAGFLGAGGS-----------------------
MMAR_3303|M.marinum_M               ASGGHGGPGGVGGVGGRVVGLFGSGGGGG---------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          APGGPGVPTGGEGGVVTPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGE
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      ------------------------------------------PSPRPGGP
Mvan_5676|M.vanbaalenii_PYR-1       ------------------------------------------PDVEPADG
Mb3537|M.bovis_AF2122/97            -AGNNSTNAPVGGEGGAGGDGGAGGAGGAANGGTAGSQGTGGVGGDGGAG
Rv3507|M.tuberculosis_H37Rv         NAGNNSTNAPVGGEGGAGGDGGAGGAGGAANGGTAGSQGTGGVGGDGGAG
MUL_4280|M.ulcerans_Agy99           -------------------DGGAGGTG---------------VNHEGGAG
MMAR_3303|M.marinum_M               ----------------AGGDGGVGGTGAQG--------APGTQSFSAGTG
TH_3810|M.thermoresistible__bu      ---------------------------------------------YRTTD
MAB_0112|M.abscessus_ATCC_1997      ------------------------------------------KPGSAGST
Mflv_3843|M.gilvum_PYR-GCK          GGVVTPPAPGAPGAPVVDEAGVVTPPAPGGPGVPAVGDTAVVTPPAPGAP
MAV_4827|M.avium_104                ------------------------------------DYLYVPVDPEPGDD
MLBr_01828|M.leprae_Br4923          --------------------------------------TLVQPLITSLTN
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      GHTGQA-------------------PTHGHSRPPMHTGTRHP--------
Mvan_5676|M.vanbaalenii_PYR-1       GAVAES-------------------DDAGDITG--RDTDPEP--------
Mb3537|M.bovis_AF2122/97            GNGGGGKAGTGNSGNFGVDGEAGFSGGAGGNGGVGGAAGANGGTGGSGGN
Rv3507|M.tuberculosis_H37Rv         GNGGGGKAGTGNSGNFGVDGEAGFSGGAGGNGGVGGAAGANGGTGGSGGN
MUL_4280|M.ulcerans_Agy99           GAGGAG----------------GLIAGTGGNGGAGGTDAYS--------R
MMAR_3303|M.marinum_M               GNGGDG--------------GSGGVAGAGGSGGFLGSAGATG-------G
TH_3810|M.thermoresistible__bu      NNALDG--------------------GHGGNGGNVGFFSLFN--------
MAB_0112|M.abscessus_ATCC_1997      GKTADS--------------------AAGSAGSGTGTPGANS--------
Mflv_3843|M.gilvum_PYR-GCK          GTPAVNSVETFSPPAPPAATPPSSGSVETFSPPAPPAPGTGTNSTVEIST
MAV_4827|M.avium_104                ELAYSAVG-----------------EEDAESPTVVIEKLFLPEDSEPRRR
MLBr_01828|M.leprae_Br4923          HPFFQG-------------------MFSGFDPWLPSLGNPLSFLSPFNIA
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      -GKPPRPGPPRPG------------------------HGHPTKTGHPD--
Mvan_5676|M.vanbaalenii_PYR-1       -LPDPADGEPQPS------------------------EDAPVADKEPE--
Mb3537|M.bovis_AF2122/97            GGDGGAGGIGGAGGNGIPGTGTEPAGGTGAKGGDGGDGGAGGAGGNAGGA
Rv3507|M.tuberculosis_H37Rv         GGDGGAGGIGGAGGNGIPGTGTEPAGGTGAKGGDGGDGGAGGAGGNAG--
MUL_4280|M.ulcerans_Agy99           GGAGGAGGTGGTGGTDMSDS-----------------GGTGGAGGNAG--
MMAR_3303|M.marinum_M               AGDGGRGGTGGLGGVGTSTNG----------------GAAGGTGGRGG--
TH_3810|M.thermoresistible__bu      --LGGAGGWGGSG-----------------------VDGVDVVGGNPD--
MAB_0112|M.abscessus_ATCC_1997      SAPGGSNGSSGGGIGGVGTTVG---------------TTLPHSGGAAG--
Mflv_3843|M.gilvum_PYR-GCK          PPPPGTPGLPSEGSTTYTTPPTPEITLNPANSG--IDIATPPAPGLPG--
MAV_4827|M.avium_104                PVLLVGSGLAVVGISAVLALEIALAIG-------IRTTGTVALQPTPN--
MLBr_01828|M.leprae_Br4923          FALGTPMDIGSYVGYLSQTFAFIG-----------ADLAAAFASGNPVTI
                                           .                                          

MSMEG_6433|M.smegmatis_MC2_155      -------------------------------------PPQQTDPSHTPTR
Mvan_5676|M.vanbaalenii_PYR-1       -------------------------------------EPR-------PPC
Mb3537|M.bovis_AF2122/97            GGNGGAGGQGGNAGQGGAGGAGGNAVIPGDGVGKAPHGGAGGSGGDGGKG
Rv3507|M.tuberculosis_H37Rv         ----GAGGQGGNAGQGGAGGAGGNAVIPGDGVGKAPHGDAGGSGGDGGKG
MUL_4280|M.ulcerans_Agy99           ----------LLFGSGGAGGAGGAAVALND------VGGAGGAGGNAGLF
MMAR_3303|M.marinum_M               ----------LSGGVGGTDGAGG-------------DGGQGGSGGAVGTG
TH_3810|M.thermoresistible__bu      ---------------GGTPGAHG---------------ESHTPGVYTDRQ
MAB_0112|M.abscessus_ATCC_1997      -------------------------------------VHTPTAEGAAATE
Mflv_3843|M.gilvum_PYR-GCK          APLEATANITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTTP
MAV_4827|M.avium_104                ---------------------------------QHLIVPTEQAPAPPPVQ
MLBr_01828|M.leprae_Br4923          G--------------------------------FTLLFTTIEAIGTIITD
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      PSHTRPTRP-----------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       CKDGDKDCE-----------------------------------------
Mb3537|M.bovis_AF2122/97            GQGGSGGTGGSGAPIGGGAGGTGGSGGHAGKGGAGGIGAQGTTITVPGNG
Rv3507|M.tuberculosis_H37Rv         GQGGSGGTGGSGAPIGGGAGGTGGSGGHAGKGGAGGIGAQGTTITVPGNG
MUL_4280|M.ulcerans_Agy99           GNGGVGGVGGVGA-------GDGGAGGRAG--------------LVIGNG
MMAR_3303|M.marinum_M               ATAGAGGAGGAGAAATSGGPGYGGGGGGGGGGAR----------VLPTSG
TH_3810|M.thermoresistible__bu      GEDGEDGTG-----------------------------------------
MAB_0112|M.abscessus_ATCC_1997      SSAGTGTHTEEHPSLKG---------------------------------
Mflv_3843|M.gilvum_PYR-GCK          DTPGAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGAPANA
MAV_4827|M.avium_104                ASAPQPKISVPEPVAAPKPLSP----------------------------
MLBr_01828|M.leprae_Br4923          TIALVKTMIEQSFVLLP---------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            GNAGDGGNGGGGGAGGTGGDGATGTPAGNGGNGGNAGDGGNGGSGDFGGN
Rv3507|M.tuberculosis_H37Rv         GNAGDGGNGG------------------------NAGAGGNGGSGDFGGN
MUL_4280|M.ulcerans_Agy99           GAGGAG-----------------------------------GESFGFG--
MMAR_3303|M.marinum_M               GITSGTATGG------------------------------EGGVGGAG--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          AVDVATPPAPG------------------------VPGAPVVGEAAVTTP
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --PGWPGWPGWPPHHGHWPTKPTKPTKPTEPTEPTEPTEP----------
Mvan_5676|M.vanbaalenii_PYR-1       --PGWP-WP-WP-----WPDDPDDRPKPDDGYGEGRPEG-----------
Mb3537|M.bovis_AF2122/97            TTSGASGSGGNGGNAGTAGSGGAGGTGGTGLSGGNGGNGG------DGGN
Rv3507|M.tuberculosis_H37Rv         TTSGASGSGGNGGNAGTAGSGGAGGTGGTGLSGGNGGNGGNGGNGGDGGN
MUL_4280|M.ulcerans_Agy99           --AGVGGAGGNGGNGVLIGNGGNAGTGGTGLSTGSTGAGG----------
MMAR_3303|M.marinum_M               TTVAAGGVGGHGGNATLAASDAGSSADGT-ATGGAGGAGG----------
TH_3810|M.thermoresistible__bu      --TGIGGRGGNGGSSSGTHPMAEDGEHVKALDGRPGLDGG----------
MAB_0112|M.abscessus_ATCC_1997      -ALGSVAGALAPKTETATTPKTETATSPHTSTAPGATAETP---------
Mflv_3843|M.gilvum_PYR-GCK          GAPGVPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPG--------
MAV_4827|M.avium_104                -PVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP---------
MLBr_01828|M.leprae_Br4923          --MILPLLTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLP---------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            GAHGTVGAQFVPATSLPTPNGGAGGNGGTGSNGGAPGPAGAPGPTTGGNA
Rv3507|M.tuberculosis_H37Rv         GAHGTVGAQFVPATSLPTPNGGAGGNGGTGSNGGAPGPAGAPGPTTGGNA
MUL_4280|M.ulcerans_Agy99           ---------------------------ISGLLLGLDGFNAPASTSALHNL
MMAR_3303|M.marinum_M               ----------------------------TNHASGGRGGDATISTSGGGTI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          -----------VPGVPAGGDAGVVTPPAPGVPGAPAATEAGLATPPGPGA
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            GSQGIGGDGGNGGDGGKGGDGADAVNVVFMPTEPQAATGTAGSAGDPTGG
Rv3507|M.tuberculosis_H37Rv         GSQGIGGDGGNGGDGGKGGDGADAVNVVFMPTEPQAATGTAGSAGDPTGG
MUL_4280|M.ulcerans_Agy99           QQQALG----------------------VINEPTQALTGR------PLIG
MMAR_3303|M.marinum_M               TG----------------------------GTATGGVGGAG-----TTGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          PGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPVAPVEGAGGAVPPA
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01828|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      -----------------------------------------------TRP
Mvan_5676|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3537|M.bovis_AF2122/97            NGGPGTPGSPMVAPPPPTPITQVQQGGDGGAGGTGSTNANDGTATGGKGG
Rv3507|M.tuberculosis_H37Rv         NGGPGTPGSPMVAPPPPTPITQVQQGGDGGAGGTGSTNANDGTATGGKGG
MUL_4280|M.ulcerans_Agy99           NGTPGAAGS-----------------------------GTDGTPGGWLLG
MMAR_3303|M.marinum_M               SGGGGGSGALFAN------------------------GAGSSASGSAIGG
TH_3810|M.thermoresistible__bu      NGSHG-----------------------------------------GNGG
MAB_0112|M.abscessus_ATCC_1997      ---------------------------------------TAGTTHPEHES
Mflv_3843|M.gilvum_PYR-GCK          GPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGGGAGGAAG
MAV_4827|M.avium_104                ---------------------------------------------VPVPV
MLBr_01828|M.leprae_Br4923          -------------------------------------------------S
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      TPTTTVIPG-----GVDVGGGNGVGPNEAPEVPRPQVPDMQL--------
Mvan_5676|M.vanbaalenii_PYR-1       VPSVRPLPG-----GVIR-------PGIEPPVAEPEDPGVLD--------
Mb3537|M.bovis_AF2122/97            EGGVGSILGGPGGNGGTGGNASATGTNGVANAGNGGKGGDGGQFGAGGNG
Rv3507|M.tuberculosis_H37Rv         EGGVGSILGGPGGNGGTGGNASATGTNGVANAGNGGKGGDGGQFGAGGNG
MUL_4280|M.ulcerans_Agy99           DGGAAGLLG----TGGTGG-AGARLAGGAG--GTGGAGGAGG-WLLGDGG
MMAR_3303|M.marinum_M               YGGAGTTGG----LGGVGGYAQVSASNGGTATGTVS-GGYGGAGTTGGHG
TH_3810|M.thermoresistible__bu      HGGRGGFLG----IGGSGG--------------WGGHGGNGG--------
MAB_0112|M.abscessus_ATCC_1997      SAEEPKVPGVTVNMGGRTIIIWKKKPSTSTHTPGAGTGTNPG--------
Mflv_3843|M.gilvum_PYR-GCK          GAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGGPVGGPGA
MAV_4827|M.avium_104                RIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG--------
MLBr_01828|M.leprae_Br4923          APPVAAVAPVVPPSMPTLASIPTPTPMPAPAASTAPVVTPPG--------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      ---------------PGPRVVQNSG------------GGAAAEPPGAAAE
Mvan_5676|M.vanbaalenii_PYR-1       ---------------TVPGIGVAAG------------NGPEA--------
Mb3537|M.bovis_AF2122/97            GAGGSVTD---GSAGSTAGNGGNGGNATNGTIAGQPAGGNGSAGGKGGDG
Rv3507|M.tuberculosis_H37Rv         GAGGSVTD---GSAGSTAGNGGNGGNATNGTIAGQPAGGNGSAGGKGGDG
MUL_4280|M.ulcerans_Agy99           GGGGGASG---GGGGASGGTGGTGG-----------AGGLLSAGGAGGVG
MMAR_3303|M.marinum_M               GGGGNAFLR-ANGAGSSASGISIGG-----------AGGAGTAGGYGGSG
TH_3810|M.thermoresistible__bu      ---------------DTDADGGNGG-----------DGGNGGSAGRGGTG
MAB_0112|M.abscessus_ATCC_1997      ----------HESEGDRDHVINLPG-------FPALGGATNPDAPFGGAA
Mflv_3843|M.gilvum_PYR-GCK          LPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGEA
MAV_4827|M.avium_104                -----------TVPQSPPQHQTPPG------------EGTPPKPDGPGNY
MLBr_01828|M.leprae_Br4923          ----------------PPPVTAPPS------------VTGAGVESFGYLV
                                                            .                         

MSMEG_6433|M.smegmatis_MC2_155      AVAPPVLLPVVVAPVIVPPALAAPQPDGGGGPGGTEP-------------
Mvan_5676|M.vanbaalenii_PYR-1       ----PISVPILVTVPTGGGASAGPSVAGSGGASASPR-------------
Mb3537|M.bovis_AF2122/97            GNIAAGATGTAGNGGNGGNGNDGAVNAGTGGSGGNGGNAGGGGANGGDGG
Rv3507|M.tuberculosis_H37Rv         GNIAAGATGTAGNGGNGGNGNDGAVNAGTGGSGGNGGNAGGGGANGGDGG
MUL_4280|M.ulcerans_Agy99           G---AGGYNTSGPGGNGGSGGNAGTLFGSGG-GGNGG-----------SG
MMAR_3303|M.marinum_M               N--YASIRGYSGATVTDGTATGGGGGAGTGGRGGLGG-----------SA
TH_3810|M.thermoresistible__bu      G-----LRGVFG--INGGNGR-----AGLGGRGXXXX-------------
MAB_0112|M.abscessus_ATCC_1997      GTRTPGGNPSIHTGPVAPPTVPTPKAPAVAIATPPAP------------P
Mflv_3843|M.gilvum_PYR-GCK          GVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPPAPGVPG
MAV_4827|M.avium_104                GGGHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVP---------TPG
MLBr_01828|M.leprae_Br4923          GRLPSTARGVVGTSVRQQSSAPDRIEAPDAAATPQEQ-------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      ----RRPAATPTLKFQTPATGQPQAVGALDAGAPP---------------
Mvan_5676|M.vanbaalenii_PYR-1       ----QIVESTPPRQLSPAPAGR-------DFAVPP---------------
Mb3537|M.bovis_AF2122/97            AGGAGGAGGRGGKGIDGGFGGDGGNGGSNNGTGAGGNGGNGGTGGVGSVG
Rv3507|M.tuberculosis_H37Rv         AGGAGGAGGRGGKGIDGGFGGDGGNGGSNNGTGAGGNGGNGGTGGVGSVG
MUL_4280|M.ulcerans_Agy99           YSGIGGTGGTGGNAVLLGGGGAGGAGG-ISFTGAGGQGGAGGTG-----G
MMAR_3303|M.marinum_M               TLFANGAGSSVATGAATG--GVGGAGSTGGIGGAGNIARITAIGG-GTVT
TH_3810|M.thermoresistible__bu      -GGGVGAAVRSGNGVFSGGGGTPSAGFGVPTT------------------
MAB_0112|M.abscessus_ATCC_1997      VLAPLAPVVPPTPPVVTVKQAEGGRGGDVVVTAGGTKQPEAVTKP-----
Mflv_3843|M.gilvum_PYR-GCK          APVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTVPGNAGTP
MAV_4827|M.avium_104                TGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGG-----
MLBr_01828|M.leprae_Br4923          ---ARSRWRRRAKVTPFDSSGSPNPKAAPTASDQGAG-------------
                                                        .                             

MSMEG_6433|M.smegmatis_MC2_155      ----------------ASFRAGYTDYLRTAEVFDIVAVAVPGTAG-----
Mvan_5676|M.vanbaalenii_PYR-1       ----------------SVNRAGYGDYLRSAGISQVAALAVPGLAG-----
Mb3537|M.bovis_AF2122/97            AAGGDGGNGGTGGFAGFGGTAGNGGSGGTGGAGGDGGTGGGGGNGGTGVI
Rv3507|M.tuberculosis_H37Rv         AAGGDGGNGGTGGFAGFGGTAGNGGSGGTGGAGGDGGTGGDGGNG---VI
MUL_4280|M.ulcerans_Agy99           QLSGNGGSGGTG---GEGDYVGGADSGGAGGAGGNAGLTGDGGNG-----
MMAR_3303|M.marinum_M               SSATNGGAGGDGITDGIGG-NGGGSTFTANTGGTIDTSTGTGGNG-----
TH_3810|M.thermoresistible__bu      ----------------IQFPAGSCTSRAVSREGIMPSSRAASARA-----
MAB_0112|M.abscessus_ATCC_1997      -------IQQFVAAETIAPRTGYTDYLRLTKTSEIAAVAIPGAAG-----
Mflv_3843|M.gilvum_PYR-GCK          STPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGTPGSTLTL
MAV_4827|M.avium_104                --------------GHLPTPGAGTPGGGLGGFGGGHAPAPGGGLG-----
MLBr_01828|M.leprae_Br4923          ----------------TLGLAGTARQASSGPATGLVTLSNGTFSD-----
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      -----------LLGLTGLGGLVG-------------------YRQAKAGV
Mvan_5676|M.vanbaalenii_PYR-1       -----------ILILTGVGGYVG-------------------YRQAKAGQ
Mb3537|M.bovis_AF2122/97            AGGGGTGGNGGASGAGGAGGTGGFAGNGNAGGNGGTGGASEDGDNGNAGS
Rv3507|M.tuberculosis_H37Rv         AGGGGTGGNGGASGAGGAGGTGGFAGNGNAGGNGGTGGASEDGDNGNAGS
MUL_4280|M.ulcerans_Agy99           -------GSGGTPGSPGGGGTG----------------GALIGQDGLARL
MMAR_3303|M.marinum_M               ---------GSGTGLGNTGGNGG--------------AADLTAPPDWMGV
TH_3810|M.thermoresistible__bu      -------------GAACASSTSR-------------------SRRSFCCS
MAB_0112|M.abscessus_ATCC_1997      -----------IAMMTFVGAALG-------------------YRQAKAGH
Mflv_3843|M.gilvum_PYR-GCK          TDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPGTPSPIA
MAV_4827|M.avium_104                --------GGGGHAPAPGGGLGG-------------------FGGGHSGG
MLBr_01828|M.leprae_Br4923          -----------SPRAPMLPRTWG-------------------ADPTFCYN
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      VVRSS-ASRFMP--------------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       GVRASGIARFMN--------------------------------------
Mb3537|M.bovis_AF2122/97            GATGGTGGNGGTGGDGGAAGLGGVA-------------------------
Rv3507|M.tuberculosis_H37Rv         GATGGTGGNGGTGGDGGAAGLGGVA-------------------------
MUL_4280|M.ulcerans_Agy99           AVTGR---------------------------------------------
MMAR_3303|M.marinum_M               DLFGTPGANVP---------------------------------------
TH_3810|M.thermoresistible__bu      RA------------------------------------------------
MAB_0112|M.abscessus_ATCC_1997      TVRASAAARFLE--------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          PLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQG
MAV_4827|M.avium_104                GLGGLGGGHK----------------------------------------
MLBr_01828|M.leprae_Br4923          AADIGPAGGWDDE-------------------------------------
                                                                                      

MSMEG_6433|M.smegmatis_MC2_155      -------------------------------
Mvan_5676|M.vanbaalenii_PYR-1       -------------------------------
Mb3537|M.bovis_AF2122/97            -------------------------------
Rv3507|M.tuberculosis_H37Rv         -------------------------------
MUL_4280|M.ulcerans_Agy99           -------------------------------
MMAR_3303|M.marinum_M               -------------------------------
TH_3810|M.thermoresistible__bu      -------------------------------
MAB_0112|M.abscessus_ATCC_1997      -------------------------------
Mflv_3843|M.gilvum_PYR-GCK          DSAATPPAAEVPRVVTGAAPTGDRRDRWGNR
MAV_4827|M.avium_104                -------------------------------
MLBr_01828|M.leprae_Br4923          -------------------------------