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MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQAYQALSAQAA LFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIG NGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVG GIGGAGGAGGNGGLLFGAGGAGSVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNG GLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGG AGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGAGGFGF GGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAILVGNGGNGGNAGSGTPNGSAGTGGAGG LLGKNGMNGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1849c | PE_PGRS33 | - | 100% (501) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | e-174 | 55.85% (607) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1797 | PE_PGRS31 | e-155 | 52.38% (630) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 8e-97 | 48.48% (495) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1818c | PE_PGRS33 | 0.0 | 99.20% (501) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-13 | 39.13% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-46 | 35.98% (378) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0478 | - | 1e-163 | 57.27% (571) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 1e-27 | 38.49% (265) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-75 | 38.96% (575) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 5e-38 | 37.14% (377) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0212 | - | 1e-162 | 52.44% (635) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-93 | 47.49% (459) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 ---------MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLA
Rv1818c|M.tuberculosis_H37Rv ---------MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLA
MMAR_0478|M.marinum_M ---------MSFVSVIPEQLTAAATNLAGVGSTISTANATAAGPTAAALA
MUL_0212|M.ulcerans_Agy99 ---------MSFVNVTPEAVAAAASDLTGIGSVLGEANAVAARATTTVLA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_4332|M.thermoresistible__bu ---------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPR------
MAB_4284c|M.abscessus_ATCC_199 ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV
MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAP
MAV_1346|M.avium_104 --------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAP
. . . ..
Mb1849c|M.bovis_AF2122/97 AAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAE
Rv1818c|M.tuberculosis_H37Rv AAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAE
MMAR_0478|M.marinum_M AGADDVSAAVSSFFGAYARDYQAFSVQVEALHDQFVRAVTSGAASYAGAE
MUL_0212|M.ulcerans_Agy99 AGGDEVSAAIAALFSFHGQSYQTLGAQAEAFHAQFAQLMANGAGTYASAE
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_4332|M.thermoresistible__bu --------------------------------------TVEYEYSLVACD
MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP
MLBr_01183|M.leprae_Br4923 PAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTE
MAV_1346|M.avium_104 AAADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATE
.
Mb1849c|M.bovis_AF2122/97 AASAAPLEGVLDVINAPALALLGRPLIGNGANGAP---------------
Rv1818c|M.tuberculosis_H37Rv AASAAPLEGVLDVINAPALALLGRPLIGNGANGAP---------------
MMAR_0478|M.marinum_M ATSVQQIL--LDAINAPTQALLGRPLIGNGANAAP---------------
MUL_0212|M.ulcerans_Agy99 AANAAPFQGLLGAVNAPVQTLTGRPLIGNGANGAP---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_4332|M.thermoresistible__bu STLPLMCEAGDSVGGLGGASHDRSAFSASALGMAS---------------
MAB_4284c|M.abscessus_ATCC_199 RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN--------------
MLBr_01183|M.leprae_Br4923 TAN------------------------------HDSL-------------
MAV_1346|M.avium_104 AANRVNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLG----------TS
Mb1849c|M.bovis_AF2122/97 -GTGANGGDGGILIGNG---------------------------------
Rv1818c|M.tuberculosis_H37Rv -GTGANGGDGGILIGNG---------------------------------
MMAR_0478|M.marinum_M -GSGANGGDGGILYGNG---------------------------------
MUL_0212|M.ulcerans_Agy99 -GTGANGGAGGWLIGNG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_4332|M.thermoresistible__bu FGPDWNPGGAFLG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQ-------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 IG------------------------------------------------
Mb1849c|M.bovis_AF2122/97 ---------------GAGGSGAAGMPG--------------GNGGAAGLF
Rv1818c|M.tuberculosis_H37Rv ---------------GAGGSGAAGMPG--------------GNGGAAGLF
MMAR_0478|M.marinum_M ---------------GAGGSGAAGGNG--------------GAGGAAGLV
MUL_0212|M.ulcerans_Agy99 ---------------GAGGSGAPGLNG--------------GAGGAAGLI
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_4332|M.thermoresistible__bu ---------------LIGPGGLLIGDG---------------LNGTDAYI
MAB_4284c|M.abscessus_ATCC_199 ---------------FGNRDTTAIGDG------------AVAVGGSNSGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------WAQNVGAAASDF
Mb1849c|M.bovis_AF2122/97 GNGGAGGAGGNVASG---------------------TAGFGGAGGAGGLL
Rv1818c|M.tuberculosis_H37Rv GNGGAGGAGGNVASG---------------------TAGFGGAGGAGGLL
MMAR_0478|M.marinum_M GNGGAGGAGGNNAAGGSGGAGGLLYGNGGAGGIGGTSAGSGGAGGAGGLL
MUL_0212|M.ulcerans_Agy99 GTGGAGGAGGSSSTVN---------------------GGLGGTGGAGGWL
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_4332|M.thermoresistible__bu DENGVFHEATRG----------------------GNGGLLWGNGGKGGN-
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNG----------------DVRDSNIINADHGSNVGVDQSQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ITLGEGQFAPVP-----------------------------GAAGIPNFN
Mb1849c|M.bovis_AF2122/97 YGAGGAGGAGGR----------------AGGGVGGIGGAGGAGGNGG---
Rv1818c|M.tuberculosis_H37Rv YGAGGAGGAGGR----------------AGGGVGGIGGAGGAGGNGG---
MMAR_0478|M.marinum_M FGTGGAGGTGG-----------------FGGGLMTSGGAGGTGGAGG---
MUL_0212|M.ulcerans_Agy99 LGNGGAGGAGGASAIPLGPDLIGKGGAGGPGGLFGAGGLGGAGGFGG---
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGG-----------------IGGAGSTGAVGGVGGKG----
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGG-----------------VGGVGATGGAGGVGGKG----
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISA-----------------GGDGGSATGADSLGGRGGTSW
TH_4332|M.thermoresistible__bu -GLDAGLYTVPD-----------------PDNPGSTIQMYFEASDG----
MAB_4284c|M.abscessus_ATCC_199 TRVGGDYTNVSG-----------------HGSADIDKSVTVVDDHSQRNT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PGLTAATTAGPP----------------APAAPAAAAGAPVLASMGR---
Mb1849c|M.bovis_AF2122/97 -------------------LLFGAGGAGSVGG--LAADAGDG--------
Rv1818c|M.tuberculosis_H37Rv -------------------LLFGAGGAGGVGG--LAADAGDG--------
MMAR_0478|M.marinum_M -------------------LLFGTGGSGGAGGGSNAFTAGDG--------
MUL_0212|M.ulcerans_Agy99 -------------------SGGGAGGQGGAGGLLSGLVGAGG--------
Mflv_5091|M.gilvum_PYR-GCK IQGGQG-------------LQGGKGGDGGAGGKGGDADSMGS--------
Mvan_1264|M.vanbaalenii_PYR-1 IQGGQG-------------LQGGQGGDGGTGGTGGDATSMGE--------
MSMEG_0868|M.smegmatis_MC2_155 VQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATG
TH_4332|M.thermoresistible__bu -------------------------ADGGRGG------------------
MAB_4284c|M.abscessus_ATCC_199 TNINDS-------------FNTDRSTNIGSGNTTNTEIGSHN--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------GPSIGGLSVPPSWAPG--------
Mb1849c|M.bovis_AF2122/97 --------------------GAGGDGGLFFG---------------VGGA
Rv1818c|M.tuberculosis_H37Rv --------------------GAGGDGGLFFG---------------VGGA
MMAR_0478|M.marinum_M --------------------GAGGAGGLLFG---------------TGGS
MUL_0212|M.ulcerans_Agy99 --------------------GHGGTGGYGGG---------------AGGA
Mflv_5091|M.gilvum_PYR-GCK ----------AGATGGKGGNGGNGGRGGLFG---------------KGGN
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGATGGKGGNGGNGGRGSLFG---------------RGGN
MSMEG_0868|M.smegmatis_MC2_155 NTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGN
TH_4332|M.thermoresistible__bu ---------------------------FLFG---------------NGGD
MAB_4284c|M.abscessus_ATCC_199 ----------------------QANIGTSTS---------------AGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 GGAG-------------------------------GTG------------
Rv1818c|M.tuberculosis_H37Rv GGAG-------------------------------GTG------------
MMAR_0478|M.marinum_M GGDGGLAPGAM-----------------FGNGGHGGTGGAGGTLSGIGGH
MUL_0212|M.ulcerans_Agy99 GATGGGNTG-----------------------GIGGDGGSAGMLFSNSGA
Mflv_5091|M.gilvum_PYR-GCK AGNGAD----------------------GGTGGAGGAGGTGG-TGGAGGT
Mvan_1264|M.vanbaalenii_PYR-1 AGNGGN----------------------GGTGGNGGNGGTGG-TGGNGGT
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGD
TH_4332|M.thermoresistible__bu GGNGGN---------------------------VGGKNGADPVTATVAAD
MAB_4284c|M.abscessus_ATCC_199 AAVGGN----------------------AGLAGNAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 ---------------------------------TNVTGG-AGGAGGNGGL
Rv1818c|M.tuberculosis_H37Rv ---------------------------------TNVTGG-AGGAGGNGGL
MMAR_0478|M.marinum_M GG---------------------------AGGLGQVSGG-AGGDGGNGGV
MUL_0212|M.ulcerans_Agy99 GG---------------------------AGGASELADGGAGGAGGNGGW
Mflv_5091|M.gilvum_PYR-GCK GG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGV
TH_4332|M.thermoresistible__bu KS----------------------------------VAGGNGGNGGRGGL
MAB_4284c|M.abscessus_ATCC_199 GN---------------------------AGLAGNAGLAGNAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------GVAPAANATPAQLVGAGF
Mb1849c|M.bovis_AF2122/97 LFGAGGVGGVGGDGVAFLGTAPGGPGGAG-------GAGGLFGVGGAGG-
Rv1818c|M.tuberculosis_H37Rv LFGAGGVGGVGGDGVAFLGTAPGGPGGAG-------GAGGLFGVGGAGG-
MMAR_0478|M.marinum_M FFGGGGDGGIGGHGITGSGGS-GGSGGSGGFLPGGAGVAGLIGDGGAGG-
MUL_0212|M.ulcerans_Agy99 LLSNGGVGGAGGAGADAVGPPFGIPAGSGSGGGAGGAGGVFFGNGGAGG-
Mflv_5091|M.gilvum_PYR-GCK G-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 G-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 SEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGT
TH_4332|M.thermoresistible__bu LFGLGGNGGNGGWSTTSYLDARGGNGGNG----GLGGVLRPGGLLSLLLP
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAG--LAGNAGLAGNAGLAGNAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 TSAAPDTAPVTAVPGGVPSMATAGRGGYGLGAPRYGVKPTVMPKPAI---
Mb1849c|M.bovis_AF2122/97 --------AGGIG-------------------------------------
Rv1818c|M.tuberculosis_H37Rv --------AGGIG-------------------------------------
MMAR_0478|M.marinum_M --------HGGSGGSGGGT--------------GGSGGSAGT--------
MUL_0212|M.ulcerans_Agy99 --------AGGTGGDGGGT--------------GGAGGAAGNG-------
Mflv_5091|M.gilvum_PYR-GCK -------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQG
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFG
MSMEG_0868|M.smegmatis_MC2_155 YVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRG
TH_4332|M.thermoresistible__bu --------SGAASEPGGLF-------------TGGNGGNGGLAIANHWVG
MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAG-------------LAGNAGLAG----NAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 ------------------------LVGNGGAGGSGGS-------------
Rv1818c|M.tuberculosis_H37Rv ------------------------LVGNGGAGGSGGS-------------
MMAR_0478|M.marinum_M ------------------------LLGNGGAGGGGGSGSTTA--------
MUL_0212|M.ulcerans_Agy99 -----------------------VLIGNGGNGGIGGA-------------
Mflv_5091|M.gilvum_PYR-GCK GQGGQGG-----------------TGGTGGQGG-LGGGGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 GQGGQGG-----------------TGGTGGQGG-LGGVGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 GKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAY
TH_4332|M.thermoresistible__bu -----------------------ITDGVPGPDDDAVSSSAYG--------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAG-----------------NAAVAGNAAVAGNAAVAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 -----------------------ALLWGDGGAGGAGGVGS-------TTG
Rv1818c|M.tuberculosis_H37Rv -----------------------ALLWGDGGAGGAGGVGS-------TTG
MMAR_0478|M.marinum_M --------------GGGGSGGDAGALFGNGGAGGAGGSGA-------ATG
MUL_0212|M.ulcerans_Agy99 -----------------------AGLWGTGGTGGSGG-----------SG
Mflv_5091|M.gilvum_PYR-GCK ---------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTG
MSMEG_0868|M.smegmatis_MC2_155 NVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAG
TH_4332|M.thermoresistible__bu ---------------GHGGHGAGPGSGGNGGSAVANSLG-------NAIA
MAB_4284c|M.abscessus_ATCC_199 -------------NAAVGGVLNTGVSGAIGGSSHVGGAIN------ESLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 GAGGAGGNAGLLV--GAGGAGGAGALGG--GATG----------------
Rv1818c|M.tuberculosis_H37Rv GAGGAGGNAGLLV--GAGGAGGAGALGG--GATG----------------
MMAR_0478|M.marinum_M GSGGTGGSSALLF--GTGGVGGVGGSGGDSGGTGGAGGQGG----AMFGN
MUL_0212|M.ulcerans_Agy99 GTGATGGFSGLLAS-GDGGAGGAGGAGGAGGLLDGLVG------------
Mflv_5091|M.gilvum_PYR-GCK GAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGK
Mvan_1264|M.vanbaalenii_PYR-1 GAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGK
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQ
TH_4332|M.thermoresistible__bu GNGGDAGRFVLIGPGGNGGNGGTGLXXXPRPRR-----------------
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 ------------VGGAGGNGGTAGLLFGAGGAGGAGGFG-----------
Rv1818c|M.tuberculosis_H37Rv ------------VGGAGGNGGTAGLLFGAG---GAGGFG-----------
MMAR_0478|M.marinum_M GGAGGGGGDGINVGGKGGAGGAAATLFGSGGTGGDGGNAGAG--------
MUL_0212|M.ulcerans_Agy99 -----------AGGGDGGAGGNAGTLFGSGGVGGDGGSGHGN--------
Mflv_5091|M.gilvum_PYR-GCK GGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQ
Mvan_1264|M.vanbaalenii_PYR-1 GGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQ
MSMEG_0868|M.smegmatis_MC2_155 GGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAA
TH_4332|M.thermoresistible__bu ---------------RRNHRRTRRRPNGRRPRPPPGR-------------
MAB_4284c|M.abscessus_ATCC_199 -----------GISESLGGSGSVGGSTAVGGGAHTGVGGGVS------TG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------FGGAGG------------------------------
Rv1818c|M.tuberculosis_H37Rv --------------FGGAGG------------------------------
MMAR_0478|M.marinum_M ------------VTFGGAGGEGGAAALLG-------------GNGGSGGH
MUL_0212|M.ulcerans_Agy99 ------------GGDGGGGGNAGLLFSDA-------------GGGGFGGF
Mflv_5091|M.gilvum_PYR-GCK GATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGT
Mvan_1264|M.vanbaalenii_PYR-1 GATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGT
MSMEG_0868|M.smegmatis_MC2_155 GTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGH
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGSTAVGG-------------GAHTGVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 --------------------------------------AGGLGGKAG-LI
Rv1818c|M.tuberculosis_H37Rv --------------------------------------AGGLGGKAG-LI
MMAR_0478|M.marinum_M GGIGNVGGKGGAGAAGAMLLGNGGDGGDGGNSLASLAGAGGAAGNAG-LI
MUL_0212|M.ulcerans_Agy99 GLAGGGGTGGSGGDAG--WLGSGGAGGAGGISVNGDAGAGGAGGTSGQLL
Mflv_5091|M.gilvum_PYR-GCK NGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-
Mvan_1264|M.vanbaalenii_PYR-1 NGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-
MSMEG_0868|M.smegmatis_MC2_155 GGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVNTGVGVGSHVGGGISESLGGSGSVG-------GSTAVGGGAHTSAIND
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 GDGGDGGAGGN---------------GTGAKGGDGGAGGG--------AI
Rv1818c|M.tuberculosis_H37Rv GDGGDGGAGGN---------------GTGAKGGDGGAGGG--------AI
MMAR_0478|M.marinum_M GSGGTGGAGGQ---------------SFSGTGGKGGDGGS--------AL
MUL_0212|M.ulcerans_Agy99 GDGGAGGAGGEA------------ELAAGGAGGSGGVGGD--------AV
Mflv_5091|M.gilvum_PYR-GCK INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GG
Mvan_1264|M.vanbaalenii_PYR-1 INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GG
MSMEG_0868|M.smegmatis_MC2_155 ASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ALGGSGSVGG----------STAVGGGAHTSAINESMNSSINASHSSSMN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1849c|M.bovis_AF2122/97 LVGNGGNGGNAGSGTPNGSAGTGGAGG-LLGKNGMNGLP-----
Rv1818c|M.tuberculosis_H37Rv LVGNGGNGGNAGSGTPNGSAGTGGAGG-LLGKNGMNGLP-----
MMAR_0478|M.marinum_M LIGDGGNGGNGGTGATAGVGGTAGTGGFLFGLDGMNGSP-----
MUL_0212|M.ulcerans_Agy99 LIGAGGNGGNGGPGTAKGDPGSGGAGG-LLGVDGLNGLS-----
Mflv_5091|M.gilvum_PYR-GCK AGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_4332|M.thermoresistible__bu --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 --------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------