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M. bovis AF2122 / 97 Mb1003c (PE_PGRS17)

annotation: PE-PGRS family protein
coordinates: 1093800 - 1094807
length: 335

MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLVAAQDEVSTAIAALFGSHGQHYQAISAQVAA
YQERFVLALSQAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKLIGDGAHGAPGTGQAGGAGGI
LWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAA
GAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFV
TNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1003cPE_PGRS17-100% (335)PE-PGRS family protein
M. bovis AF2122 / 97Mb1006cPE_PGRS18e-13563.33% (450) PE-PGRS family protein
M. bovis AF2122 / 97Mb2648cPE_PGRS457e-9066.90% (281) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-2e-2055.68% (88) triple helix repeat-containing collagen
M. tuberculosis H37RvRv0978cPE_PGRS171e-17693.73% (335) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-0938.71% (93) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_0321c-5e-1441.26% (143) hypothetical protein MAB_0321c
M. marinum MMMAR_2100-1e-6864.93% (211) PE-PGRS family protein
M. avium 104MAV_1346-4e-1532.35% (272) PE family protein
M. smegmatis MC2 155MSMEG_0868-3e-2144.10% (161) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_4332-8e-1535.53% (152) PUTATIVE -
M. ulcerans Agy99MUL_0572-2e-6864.02% (214) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_3865-7e-2644.85% (165) hypothetical protein Mvan_3865

CLUSTAL 2.0.9 multiple sequence alignment


Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------MVTFGGGATPTPTSLGAAAVDLSGTSCGLICNGQDGTGQN
MMAR_2100|M.marinum_M               MSFVSVTPEMVVAAASDLSGINSAIAQANSVAAAATTTVLPAAADEVSAA
MUL_0572|M.ulcerans_Agy99           MSYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ALAPESPLPDLKPRWERPTTAPDSETPSIT--------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGILFGNGGSGWNSDVVGMDGGNGGNGGLF--------------------
MMAR_2100|M.marinum_M               IAALFGTHAQQYQAISAELAAFHDRFVQSLNTGAGSYLRAEAANAEQGLL
MUL_0572|M.ulcerans_Agy99           IAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAAN------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------QPQGRDTAADPAEQQATSTNTTDQPTSDSLGA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ------------------GGNGGNGGNGLGGGNGGNGGNAGAFALFGNGG
MMAR_2100|M.marinum_M               GLVNAPTQALFGRPLIGDGANGAPGSGQAGGAGGLLYGNGGAGGSGGVGQ
MUL_0572|M.ulcerans_Agy99           -------------ASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGLAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           -------------------------------MSFVNVAPQLVSTAAADAA
Rv0978c|M.tuberculosis_H37Rv        -------------------------------MSFVNVAPQLVSTAAADAA
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      QPTAQVAR-QVQAPATDPAPAAPSLRPISGLLSVVTLG--TTLIPNAPTE
TH_4332|M.thermoresistible__bu      -------------------------------MPFITSG--AAFVGGAAML
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          NGGNGGVG-VVGATGAVGAPGVAGATGATGVTSGVVGGNGEDAVGYGATG
MMAR_2100|M.marinum_M               AGGAGGAAGLIGSGGAGGAGGAGGTGGAGGAGGWLYGNGGAGGVGGAGAV
MUL_0572|M.ulcerans_Agy99           TGAAGGAGGLLWGNGGNGGSGAAGQAGGAGGAAGLIGTGGAGGMGGAGGG
MLBr_01183|M.leprae_Br4923          -------------------------------MPLFLNAEPQALTAAANTL
MAV_1346|M.avium_104                -------------------------------MS-FVTTRPEALLAVASML
                                                                                      

Mb1003c|M.bovis_AF2122/97           R----------------IGSAINTANTAAAATTQVLVAAQDEVSTAIAAL
Rv0978c|M.tuberculosis_H37Rv        R----------------IGSAINTANTAAAATTQVLAAAQDEVSTAIAAL
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      P----------ADMPGVW--AVMAWARRQPMYSDPAMRTTVNPQAQLPVP
TH_4332|M.thermoresistible__bu      L----------AGPGGVS--ALEAAGSAPRTVEYEYSLVACDSTLPLMCE
Mvan_3865|M.vanbaalenii_PYR-1       ------------------------------MIDRLLALLRPTSRVSLLSP
Mflv_5091|M.gilvum_PYR-GCK          A----------AGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGK
MMAR_2100|M.marinum_M               GGAGGNTWLWGNGGAGGSGGVGSGSGGAGGSGGWLYGNGGAGGTGGVADG
MUL_0572|M.ulcerans_Agy99           AGG-------MGGSGGWLLGNGGAGGAGGVGCAGVSGGVGGTGGNAMLFG
MLBr_01183|M.leprae_Br4923          EG---------------LSAATVASNAAAAQLTTEIAPPAADDVSILLAH
MAV_1346|M.avium_104                EG---------------LGSSMDAQNAAAAAPTTSIAPAAADEVSALQAA
                                                                                      

Mb1003c|M.bovis_AF2122/97           FGSHG---------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        FGSHG---------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYL
TH_4332|M.thermoresistible__bu      AGDSVG--------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       TGAFLG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          AGDAGGAGAVGAAGAAGTVGTAGATGGTGTGANGGAGGVGGVGGTGAAGA
MMAR_2100|M.marinum_M               VGEGGGHGGAGGNARLLGTGGAGGDGGAGLAGAAGISGIAAGEAGTGGGI
MUL_0572|M.ulcerans_Agy99           NGGAGGMGGAGADGAVGAAGTAGTSTSAGGVGGAGWDATAAGVLAATGGD
MLBr_01183|M.leprae_Br4923          FFSGHG--------------------------------------------
MAV_1346|M.avium_104                QFSAYG--------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           -------------------------QHYQAISAQVAAYQERFVLALSQAG
Rv0978c|M.tuberculosis_H37Rv        -------------------------QHYQAISAQVAAYQQRFVLALSQAG
MAB_0321c|M.abscessus_ATCC_199      -----------------------------------------MAN-IISNG
MSMEG_0868|M.smegmatis_MC2_155      IGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAG-LFGNG
TH_4332|M.thermoresistible__bu      --------------------------GLGGASHDRSAFSASALG-MASFG
Mvan_3865|M.vanbaalenii_PYR-1       ------------------------LIGPGGLLIGNGVLPGQNGGLLIGNG
Mflv_5091|M.gilvum_PYR-GCK          AGGAGGLGETGTTGGAGGVGGQGTAGGTGGVGGIGGAGSTGAVGGVGGKG
MMAR_2100|M.marinum_M               GGDGGVGGDGGAGGWLFGNGGAGGIGGAGGAGGAGGFGASGDLVINQGSG
MUL_0572|M.ulcerans_Agy99           GGDSGGGGAGGNGGAGGAGGHGSALFGADGANGNGGAGGAGGNPGAPGNG
MLBr_01183|M.leprae_Br4923          -------------------------RQYQAHASQGATNHQDLIQSLLTS-
MAV_1346|M.avium_104                -------------------------TWYQQVSAQAKAIHQTLVQNLDTN-
                                                                                      

Mb1003c|M.bovis_AF2122/97           STYAVAEAASATP--------LQQIEQALLGVINTPTEALVG--------
Rv0978c|M.tuberculosis_H37Rv        STYAVAEAASATP--------LQN----VLDAINAPVQSLTG--------
MAB_0321c|M.abscessus_ATCC_199      PDG--------------------------DAGATGAQGS-----------
MSMEG_0868|M.smegmatis_MC2_155      GNGGVGWAGLDGG-NGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGT
TH_4332|M.thermoresistible__bu      PDWN---------------------PGGAFLGLIGPGGLLIG--------
Mvan_3865|M.vanbaalenii_PYR-1       ADGAPG------------------VLPGEAGGKGGNGGLLMG--------
Mflv_5091|M.gilvum_PYR-GCK          IQGGQGLQGGKGG-DGGAGGKGGDADSMGSAGATGGKGGNGGNGGRGGLF
MMAR_2100|M.marinum_M               ADGGSGGAGGAGG-AGGNGGAGGWLFSAHGAGGVGGAGGTGGTPGDGGGG
MUL_0572|M.ulcerans_Agy99           GTGGVGPDAATSGGMGGTGGDPGAVGGRGNSGAAGGAGAVAGASGAAGTI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           ---------------------------RKLIGDGAHGAPG----------
Rv0978c|M.tuberculosis_H37Rv        ---------------------------RPLIGDGANGIDG----------
MAB_0321c|M.abscessus_ATCC_199      --------------------------QGATGAAGAMANCN----------
MSMEG_0868|M.smegmatis_MC2_155      GGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYV
TH_4332|M.thermoresistible__bu      --------------------------DGLNGTDAYIDENG----------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------NGGAGGAGAPGVAG----------
Mflv_5091|M.gilvum_PYR-GCK          GKGGNAG-------------------NGADGGTGGAGGAGG---------
MMAR_2100|M.marinum_M               AHGSMAVNPGAGFGTGGNGGNGGDPGAGGAGGTGGSGAGGSRAATG----
MUL_0572|M.ulcerans_Agy99           IAG-----------------------NGGNGGAGGAGYAADGPAGP----
MLBr_01183|M.leprae_Br4923          --------------------------SSAYAGTETAN-------------
MAV_1346|M.avium_104                --------------------------ADSYGATEAANRVN----------
                                                                                      

Mb1003c|M.bovis_AF2122/97           ----------TGQAGGAGGILWGNG-------------------------
Rv0978c|M.tuberculosis_H37Rv        ----------TGQAGGNGGWLWGNG-------------------------
MAB_0321c|M.abscessus_ATCC_199      -----WIDDDCATRGGTGGTGGNGG-------------------------
MSMEG_0868|M.smegmatis_MC2_155      LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA
TH_4332|M.thermoresistible__bu      -------VFHEATRGGNGGLLWGNG-------------------------
Mvan_3865|M.vanbaalenii_PYR-1       ---------GAGGAGGNGGFFAGNG-------------------------
Mflv_5091|M.gilvum_PYR-GCK          -------TGGTGGAGGTGGTGGTGG-------------------------
MMAR_2100|M.marinum_M               ------ATGSTPSSGGNGGAGGAGADSITTGGAGAAGGTGGDGGLVGDGG
MUL_0572|M.ulcerans_Agy99           ----AIGNGGDGGHGGAGGFYGNGGAG-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -------TSAAALQGLAPNVIPNAA-------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           ----------------------------------GNGGSGAPGQAGG---
Rv0978c|M.tuberculosis_H37Rv        ----------------------------------GNGGSGAPGQAGG---
MAB_0321c|M.abscessus_ATCC_199      --------------------------------PGGAGGPGGHGGVID---
MSMEG_0868|M.smegmatis_MC2_155      NGGTVDG--------HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIA---
TH_4332|M.thermoresistible__bu      ----------------------------------GKGGNGLDAGLYT---
Mvan_3865|M.vanbaalenii_PYR-1       ----------------------------------GAGGAGGNGSTVN---
Mflv_5091|M.gilvum_PYR-GCK          --------------------------IGGAGSTGGTGGTGGTGGTGG---
MMAR_2100|M.marinum_M               AGGDGGAGLGGAPGTSVIFPGGQPGSSGGDGGAGGAGGAGGDGGLVAGNG
MUL_0572|M.ulcerans_Agy99           ---------------------GAGGNSAPGGGTGGNGGTGGDSGAMGSSG
MLBr_01183|M.leprae_Br4923          -----------------------------------------HDSL-----
MAV_1346|M.avium_104                --------------------------------PAADPPPAGTTSLGT---
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      ----FEVETFMDG--------------------------------VTLQA
MSMEG_0868|M.smegmatis_MC2_155      ----EGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTA
TH_4332|M.thermoresistible__bu      ----VPDPDNPGS-------------------------TIQMYFEASDGA
Mvan_3865|M.vanbaalenii_PYR-1       ----GPTSGGHGG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGGTGG-------------------------TGGTGGTGGKGG
MMAR_2100|M.marinum_M               GVGGAGGIGGVGGTGGDGSVGVDAAGAGQDGGVGGAGGAGGAGGAGGAGG
MUL_0572|M.ulcerans_Agy99           GRGGDGGVGTNGG---------------------AGGGGGNATSYGTANA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           AGGAAG--------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        AGGAAG--------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      KGGRGG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGG
TH_4332|M.thermoresistible__bu      DGGRGG--------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       DGGKAG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGAG------------------------------------------
MMAR_2100|M.marinum_M               EGGAGGHALAAGYADGSQGAGGAGGAGGIGGDGAAGGKGAEGAAAAGAGA
MUL_0572|M.ulcerans_Agy99           TGGAGGDGGTG---------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      RGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2100|M.marinum_M               DGNDGGNGGRGGAGGRGGDGGVGGAGPEGQTGMQGVGGAGGDGGLGGQAG
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGG
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_2100|M.marinum_M               NGSDGADAIVGGGKGGDGGDGGDPGLGGAGGQGGAGSTAGMEGLTAGDDG
MUL_0572|M.ulcerans_Agy99           ----------------------------------------------STGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --LIGNGGAGGTG-------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --LIGNGGAGGTG-------------------------------------
MAB_0321c|M.abscessus_ATCC_199      -----NGGHGG---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AAQGGNGGNGGNGWVQAYD-------------------------------
TH_4332|M.thermoresistible__bu      -FLFGNGGDGGNG-------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       -LFRGDGGAGG---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTGGDGGTGGTG-------------------------------------
MMAR_2100|M.marinum_M               PGHGGDGGAGGDGAAAVTTGSAGGDGGAGGDGGLVGDGGVGGNGGTGADG
MUL_0572|M.ulcerans_Agy99           GGSGGDGGNGGTG-------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --SIGWAQNVG---------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           ----------------------------GAVSLARAGTAGGAGRGPVGGI
Rv0978c|M.tuberculosis_H37Rv        ----------------------------GAVSLARAGTAGGAGRGPVGGI
MAB_0321c|M.abscessus_ATCC_199      ---------------------------AGGTGG----------TGGKGGD
MSMEG_0868|M.smegmatis_MC2_155      -------------PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGD
TH_4332|M.thermoresistible__bu      ------------------------GNVGGKNGADPVTATVAADKSVAGGN
Mvan_3865|M.vanbaalenii_PYR-1       ---------------------------AGGAAVRTGNGPDGQVYAGRGGD
Mflv_5091|M.gilvum_PYR-GCK          -----------------------GTGGTGGTGGTGGTGGAGDGTGGTGGT
MMAR_2100|M.marinum_M               SPGITFISPGGLSGTDGGAGSIGGTGGAGGAGGLHAGDGGAGGIGGTGGD
MUL_0572|M.ulcerans_Agy99           ------------------------HGGGGGPGGTAINYGAGDAFGGAAGK
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ---------------------------AAASDFITLGEGQFAPVPGAAGI
                                                                                      

Mb1003c|M.bovis_AF2122/97           G-------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        G-------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      ---------------------------GDDCEFG----------------
MSMEG_0868|M.smegmatis_MC2_155      GAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGV
TH_4332|M.thermoresistible__bu      --------------------------GGNGGRGG----------------
Mvan_3865|M.vanbaalenii_PYR-1       ---------------------------GGDAVVG----------------
Mflv_5091|M.gilvum_PYR-GCK          G-----------------------GTGGQGGQGGQG--------------
MMAR_2100|M.marinum_M               GGHGGSGSAGADATIAG-AAGQTGGDGGDGGAGGAGGAGGAGGLAQATGY
MUL_0572|M.ulcerans_Agy99           GGTG--------------------VVGGNGGSGGAAYNYGTG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                P-------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           -----GAGGVGGAGGAAG------------AVTTITHASFNDP-------
Rv0978c|M.tuberculosis_H37Rv        -----GAGGVGGAGGAAG------------AVTTITHASFNDP-------
MAB_0321c|M.abscessus_ATCC_199      -----RTGGNGGTGGRGG-------------DGNFAGTGGNG--------
MSMEG_0868|M.smegmatis_MC2_155      SEGEGGTGGHGGDGGRGG-------------DGALGGNGGTGGVG-----
TH_4332|M.thermoresistible__bu      --LLFGLGGNGGNGGWST-------------TSYLDARGGNGG-------
Mvan_3865|M.vanbaalenii_PYR-1       ------SGGQGGVGGDAT-------------SQGGPATSGGGG-------
Mflv_5091|M.gilvum_PYR-GCK          --GTGGTGGQGGLGGGGG-------------TGGQGGTGGTGG-------
MMAR_2100|M.marinum_M               LDGSHGSGGSGGAGGQAGNAGDGGDGADATVAGGKGGAGGNGGDAGVGGS
MUL_0572|M.ulcerans_Agy99           --NATGAGGSSGSGGAASVPNSASTATATSGSGGAGGDGTDGG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----NFNPGLTAATTAG-------------PPAPAAPAAAAG-------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------HGVAVNPGGNVYVTN-----------FGSGTVSVIN
Rv0978c|M.tuberculosis_H37Rv        --------------HGVAVNPGGNVYVTN-----------FGSGTVSVIN
MAB_0321c|M.abscessus_ATCC_199      ---------------GAILVKCQHD---------------LSLGTHPMDV
MSMEG_0868|M.smegmatis_MC2_155      LGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTA
TH_4332|M.thermoresistible__bu      -----------NGGLGGVLRPGGLLS------------LLLPSGAASEPG
Mvan_3865|M.vanbaalenii_PYR-1       --------------HGGSVAVFGDAG----------------DGGFGGYA
Mflv_5091|M.gilvum_PYR-GCK          -----------QGGTGGTGGTGGTGG----------------TGGAGGDG
MMAR_2100|M.marinum_M               GGLGGDSGNGTHAANGASAGAYGTGGNGGAGGDGADATAAGQAGGAGGAG
MUL_0572|M.ulcerans_Agy99           -----------NGGSGGFAFTFGTGN------------IIAGVGGGGGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ---------------APVLASMGRGP---------------SIGGLSVPP
                                                                                      

Mb1003c|M.bovis_AF2122/97           PAT-------NTVTGSP-------------------------------IT
Rv0978c|M.tuberculosis_H37Rv        PAT-------NTVTGSP-------------------------------IT
MAB_0321c|M.abscessus_ATCC_199      SAG-------TGGNGG---------------------------------I
MSMEG_0868|M.smegmatis_MC2_155      TGG-------NGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTAT
TH_4332|M.thermoresistible__bu      GLF-------TGGNGG---------------------------------N
Mvan_3865|M.vanbaalenii_PYR-1       GSQ-------NQATGR---------------------------------S
Mflv_5091|M.gilvum_PYR-GCK          GLGGLGGFGGSGGTGG---------------------------------Q
MMAR_2100|M.marinum_M               GDGGVVGDGGVGGNGGDGKAG-----VDGTSAVTFGASGADGGDGGAGGA
MUL_0572|M.ulcerans_Agy99           STG----VGGIGGSGGGADIN--------------------NGAFTVVPQ
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                SWA----------------------------------------------P
                                                                                      

Mb1003c|M.bovis_AF2122/97           IGNGPSGVAVSPVTGLVFVTN-----------------------------
Rv0978c|M.tuberculosis_H37Rv        IGNGPSGVAVSPVTGLVFVTN-----------------------------
MAB_0321c|M.abscessus_ATCC_199      GGGGGGGGSVGANGAT----------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGG
TH_4332|M.thermoresistible__bu      GGLAIANHWVGITDGVPGP-------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       GGDGGRGGVLSGNGGD----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGLGGPGGSTGGAGGAGGQAG-----------------------------
MMAR_2100|M.marinum_M               GGAGGDGGAVAGDGGRGGAGGDGAMGGNGGNGFDG---------------
MUL_0572|M.ulcerans_Agy99           GGAGGHGGDGATDGGAGGAGG-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                GGVAPAANATPAQLVGAGFTS-----------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           -------------------------------------------FDSNTVS
Rv0978c|M.tuberculosis_H37Rv        -------------------------------------------FDSNTVS
MAB_0321c|M.abscessus_ATCC_199      -----------------------------------------TGVFSSSSD
MSMEG_0868|M.smegmatis_MC2_155      HGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTAN
TH_4332|M.thermoresistible__bu      ----------------------------------------DDDAVSSSAY
Mvan_3865|M.vanbaalenii_PYR-1       ------------------------------------------GGIGGYAT
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------TAGKGGLFGGSGS
MMAR_2100|M.marinum_M               ---------------------LHGTTPGANGQYGGDGGEGGRGGVGGAGG
MUL_0572|M.ulcerans_Agy99           ----------------------------------FTEIDSSASVIAATGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ------------------------------------------AAPDTAPV
                                                                                      

Mb1003c|M.bovis_AF2122/97           VIDPTTNTVTGSPITVG-----------------------------TAPT
Rv0978c|M.tuberculosis_H37Rv        VIDPTTNTVTGSPITVG-----------------------------TAPT
MAB_0321c|M.abscessus_ATCC_199      CSGPGPQPNPGSPGDPG-----------------------------TSVA
MSMEG_0868|M.smegmatis_MC2_155      AANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTA
TH_4332|M.thermoresistible__bu      GGHGGHGAGPGSGGNGG-----------------------------SAVA
Mvan_3865|M.vanbaalenii_PYR-1       SIGTGPAEG-GAGGYGG-----------------------------SGGA
Mflv_5091|M.gilvum_PYR-GCK          AGKAGATGAAGASGGKGAQGATGAQGATG------------AQGATGATG
MMAR_2100|M.marinum_M               AGGAAAAGQAGSQGDGGNGGDGGDGGTPGNGGSGADGANSAIGVSAGDGG
MUL_0572|M.ulcerans_Agy99           AGGDGGSGGTGRGGTGGGGTGGGGTGGGGGVG----------INNGSGEA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                TAVPGGVPSMATAGRGGYG-------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           GVAVNPVTGEVYVTNFAGDTVSVIS-------------------------
Rv0978c|M.tuberculosis_H37Rv        GVAVNPVTGEVYVTNFAGDTVSVIS-------------------------
MAB_0321c|M.abscessus_ATCC_199      VSG---------AQGNPGQAQFLIVP------------------------
MSMEG_0868|M.smegmatis_MC2_155      TAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGAT
TH_4332|M.thermoresistible__bu      NSLG------NAIAGNGGDAGRFVLIGP----------------------
Mvan_3865|M.vanbaalenii_PYR-1       FSRG-------GDGGAGGNGLSATAPGN----------------------
Mflv_5091|M.gilvum_PYR-GCK          AAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGSQGAAGKAGAT
MMAR_2100|M.marinum_M               YGGAGGNAGAGGLGGEGGAGSTSGASGLDGSQAAGGDGGNGGFGGTGGLF
MUL_0572|M.ulcerans_Agy99           IGGAPGAGGTGAVGGDGGQGGAAYSYGTGDATGSAGAAGTAGTTGVGGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ----------LGAPRYGVKPTVMPKPAI----------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGP
TH_4332|M.thermoresistible__bu      ---------------------------GGNGGNGGTGLX-----------
Mvan_3865|M.vanbaalenii_PYR-1       ---------------------------GGSGGRGGDGGP-----------
Mflv_5091|M.gilvum_PYR-GCK          GTTG----------------ATGAAGEDGDAGSGGSGINGG---------
MMAR_2100|M.marinum_M               EAAGSGGAGG----------VGGDGSQGGDGGDGGAGGSSPGATGGWGGQ
MUL_0572|M.ulcerans_Agy99           GAGGAAYTLNG---------ASTATATGGIGGNGGDGGTAN---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGE
TH_4332|M.thermoresistible__bu      -----------------------------------------XXPRPRRRR
Mvan_3865|M.vanbaalenii_PYR-1       ------------------------------------------GGDGGLGG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------AGGAGGAGGE
MMAR_2100|M.marinum_M               GGLGGVGTAGVGGHGGDGGDAGDSGSSAFGVGSPGGGGGQGGFGVAGGGD
MUL_0572|M.ulcerans_Agy99           -------------------------------GSNGGNGGAGGYASTTGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      HNTGGNGGNGGDGSEPGPGGNGAG---------------GAGGNGGTGGT
TH_4332|M.thermoresistible__bu      NHRRTRRRPNGRRPRPPPGR------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       KGGVGSTNNGADGPDGGPAD------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGEGGDGGKGGAGAEGGAGGGGGA---------------GGSGAGGAG--
MMAR_2100|M.marinum_M               GGDGGNGGAGGFGQNGGPGGRGGGGGHSLVGPGGDGGLGGTGGNGGNGSQ
MUL_0572|M.ulcerans_Agy99           TASVGNGGRGGDGTATVATGGTGG--------------VGGNAHAPAGSP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP----------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          -----GAGGSGGSGGSGGSGGSGGAAGDSDD-------------------
MMAR_2100|M.marinum_M               PPFGSTPAGSGGDGGNGGAGGSSGFVSGQSGTDGQDGGDPSGQFGGTGGA
MUL_0572|M.ulcerans_Agy99           VPGVGGKGGNPGPGGKPGPNGADGIVV-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mb1003c|M.bovis_AF2122/97           ----------
Rv0978c|M.tuberculosis_H37Rv        ----------
MAB_0321c|M.abscessus_ATCC_199      ----------
MSMEG_0868|M.smegmatis_MC2_155      ----------
TH_4332|M.thermoresistible__bu      ----------
Mvan_3865|M.vanbaalenii_PYR-1       ----------
Mflv_5091|M.gilvum_PYR-GCK          ----------
MMAR_2100|M.marinum_M               GGSGGAGAGT
MUL_0572|M.ulcerans_Agy99           ----------
MLBr_01183|M.leprae_Br4923          ----------
MAV_1346|M.avium_104                ----------