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IDRLLALLRPTSRVSLLSPTGAFLGLIGPGGLLIGNGVLPGQNGGLLIGNGADGAPGVLPGEAGGKGGNG GLLMGNGGAGGAGAPGVAGGAGGAGGNGGFFAGNGGAGGAGGNGSTVNGPTSGGHGGDGGKAGLFRGDGG AGGAGGAAVRTGNGPDGQVYAGRGGDGGDAVVGSGGQGGVGGDATSQGGPATSGGGGHGGSVAVFGDAGD GGFGGYAGSQNQATGRSGGDGGRGGVLSGNGGDGGIGGYATSIGTGPAEGGAGGYGGSGGAFSRGGDGGA GGNGLSATAPGNGGSGGRGGDGGPGGDGGLGGKGGVGSTNNGADGPDGGPAD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3865 | - | - | 100% (333) | hypothetical protein Mvan_3865 |
M. vanbaalenii PYR-1 | Mvan_3856 | - | 1e-77 | 47.99% (398) | hypothetical protein Mvan_3856 |
M. vanbaalenii PYR-1 | Mvan_3867 | - | 1e-69 | 44.47% (371) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2186c | PE_PGRS38 | 5e-73 | 51.20% (332) | hypothetical protein Mb2186c |
M. gilvum PYR-GCK | Mflv_2178 | - | 2e-62 | 46.65% (328) | hypothetical protein Mflv_2178 |
M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | 5e-73 | 47.24% (362) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 1e-09 | 36.36% (143) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 7e-31 | 36.25% (331) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_1208 | - | 3e-73 | 49.28% (349) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 1e-21 | 43.29% (164) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_3202 | - | 2e-61 | 47.77% (314) | hypothetical protein MSMEG_3202 |
M. thermoresistible (build 8) | TH_3810 | - | 4e-38 | 40.41% (292) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3672 | - | 5e-65 | 48.95% (333) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3865|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 ---------MTKHQRLTSAVAASIVATAGVAVSQAPAPASTGTPTAHQTP Mb2186c|M.bovis_AF2122/97 -------MSFVIAAPEVMAAAATDLANIGSSISAASAAAAGPTMGILAAG Rv2162c|M.tuberculosis_H37Rv -------MSFVIAAPEVMAAAATDLANIGSSISAASAAAAGPTMGILAAG MMAR_1208|M.marinum_M -------MAFVLVAPEMVTAAASDLANIGSAINTANTAVAAPTAELLAAG MUL_3672|M.ulcerans_Agy99 -------MAYVIADLEAMAAAAADLAGVNSAIAAANGIAAVPTTAVQACA Mflv_2178|M.gilvum_PYR-GCK -------MSGTAHAPGKTRLFANVTVAVGLGG-AALGAAALLAPQASAAP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAE MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA MLBr_01556|M.leprae_Br4923 -----------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTV Mvan_3865|M.vanbaalenii_PYR-1 --------------------MIDRLLALLRPTSRVSLLSPTGAFLG---- MSMEG_3202|M.smegmatis_MC2_155 TSTSTPRWLTVTSTPEGAPATPNALYGAILPSTSPGSVTSTGSGIGHREP Mb2186c|M.bovis_AF2122/97 ADEVSVAISALFGSHAQGYQTLSAQLAAYHNQFVRALNAGAGSYASAEAA Rv2162c|M.tuberculosis_H37Rv ADEVSVAISALFGSHAQGYQTLSAQLAAYHNQFVRALNAGAGSYASAEAA MMAR_1208|M.marinum_M TDEVSEAIASLFSGHALDYQSLGARMTAFHDQFVAALTAGGGLYSSAEAA MUL_3672|M.ulcerans_Agy99 GDQVSAAVAALFAAHAQGYQSISTQMSAMHDQLVQTLSASSASYAGAEAS Mflv_2178|M.gilvum_PYR-GCK EEWLPAGPSSECPPPTDGCANVAAVGGVHGAQGPANLATPQTSGSPLFRP TH_3810|M.thermoresistible__bu ---------------VDGDGGSGGRTGLFSKLSRGGDGGDGG-------- MAB_4284c|M.abscessus_ATCC_199 SVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR MLBr_01556|M.leprae_Br4923 EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKA Mvan_3865|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 GISGSPAFTAVRAVRPGSSTARLVFAPKTSTSGTALTVTPIAVGMVGNA- Mb2186c|M.bovis_AF2122/97 NVQ--------------QTLLNAINAPTQTLLG----------------- Rv2162c|M.tuberculosis_H37Rv NVQ--------------QTLLNAINAPTQTLLG----------------- MMAR_1208|M.marinum_M AATPL------------QDLLNVVNAPTQALLG----------------- MUL_3672|M.ulcerans_Agy99 NAA--------------QASLDLINAPTQALLG----------------- Mflv_2178|M.gilvum_PYR-GCK LFGNG-----------ADAPADCVGNACNGRDG----------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 DFLSHN--------DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS- MAV_4827|M.avium_104 IDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS MLBr_01556|M.leprae_Br4923 VAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHR---------------- Mvan_3865|M.vanbaalenii_PYR-1 ----------------LIGPGGLLIGNGVL--PGQNGGLLIGNGA----- MSMEG_3202|M.smegmatis_MC2_155 ----KVTVAVDSSGRPMIGPGGWLIGNGIE--PGQNGGLLIGNGA----- Mb2186c|M.bovis_AF2122/97 --------------RPLIGNGADG-GPGQN---GGPGGLLYGNGG----- Rv2162c|M.tuberculosis_H37Rv --------------RPLIGNGADG-GPGQN---GGPGGLLYGNGG----- MMAR_1208|M.marinum_M --------------RPLIGDGADGTAPGQA---GGAGGLLYGNGG----- MUL_3672|M.ulcerans_Agy99 --------------RPLIGNGADGATVGRIGTPGGAGGLLYGNGG----- Mflv_2178|M.gilvum_PYR-GCK --------------GLIWGNGGAGANGGHG---GNAG--LVGNGG----- TH_3810|M.thermoresistible__bu ----------------LGGNGGHGGGTGIIS-----LLSLAGNGG----- MAB_4284c|M.abscessus_ATCC_199 ----FGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGD----- MAV_4827|M.avium_104 IPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPL MLBr_01556|M.leprae_Br4923 -----------EELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPG----- * . Mvan_3865|M.vanbaalenii_PYR-1 --------------DGAPGVLPGEAGGKGGNGGLLMGNGGAGGAGAPGVA MSMEG_3202|M.smegmatis_MC2_155 --------------DGGP-------GQKGGNGGFLLGNGGRGGDGLAGVN Mb2186c|M.bovis_AF2122/97 --------------NGGAGDTANPNGGNGGSAG-LIGNGGAGGAGAATGA Rv2162c|M.tuberculosis_H37Rv --------------NGGAGDTANPNGGNGGSAG-LIGNGGAGGAGAATGA MMAR_1208|M.marinum_M --------------NGAAGTNPGVAGGAGGAAG-LIGNGGAGGIGGAGGS MUL_3672|M.ulcerans_Agy99 --------------RGGDSTLAGVSGGGGGYAG-LIGNGGAGGTGGNGGS Mflv_2178|M.gilvum_PYR-GCK --------------RGGDATTPGRSGGHGGNGGRLWGNGGDGGNGAPGVL TH_3810|M.thermoresistible__bu --------------NGGNGYRTTDNNALDGGHG---GNGGNVGFFSLFNL MAB_4284c|M.abscessus_ATCC_199 --------------VRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGS MAV_4827|M.avium_104 KQVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPG MLBr_01556|M.leprae_Br4923 ---------MPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAP . . Mvan_3865|M.vanbaalenii_PYR-1 GGAGGA----GGNGGFFAGNG---------------------------GA MSMEG_3202|M.smegmatis_MC2_155 GGRAGD----GGNAGLLGNGGDGGNSVGGVEG------ANGGNAG-LIGN Mb2186c|M.bovis_AF2122/97 GGAGGNGGWLYGNGGPGGAAGLGTAGGVSPAG------GAGGAAG-LWGH Rv2162c|M.tuberculosis_H37Rv GGAGGNGGWLYGNGGPGGAAGLGTAGGVSPAG------GAGGAAG-LWGH MMAR_1208|M.marinum_M GGAGGTGGWLYGNGGAGGAGGAGAPGLVSFNGSNGGNGGNGGAAG-WWGT MUL_3672|M.ulcerans_Agy99 GGLGGN-AWLLGSGGTGGTGGAGVSSGFGGTG------GNGGLGGLLYGS Mflv_2178|M.gilvum_PYR-GCK GPAGTAPIPPSSLPAATGTRGDSPPYG------------YGNLVG---GD TH_3810|M.thermoresistible__bu GG-----------------AG---------------------------GW MAB_4284c|M.abscessus_ATCC_199 ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTN-----IGSGNTTNTEIGS MAV_4827|M.avium_104 TGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE MLBr_01556|M.leprae_Br4923 RPSASPSSMSPRPGGAVGGGGPRPPRTGVPRP---GGGRPGAPVGGRSDA Mvan_3865|M.vanbaalenii_PYR-1 GGAGGNGS---TVNGPTSG--------------GHGGDGGKAGLFRGDGG MSMEG_3202|M.smegmatis_MC2_155 GGKGGDGSPNVISNGAHIAN------------AGRGGNGGNGGLLVGSGG Mb2186c|M.bovis_AF2122/97 GGAGGAGG---SASGAPG-------------AGGAGGDGGRGGLLYGDGG Rv2162c|M.tuberculosis_H37Rv GGAGGAGG---SASGAPG-------------AGGAGGDGGRGGLLYGDGG MMAR_1208|M.marinum_M GGAGGAGGEGGAAGGDPAGIA----YGSTGGVGGNGGSGGNGGWFAGNAG MUL_3672|M.ulcerans_Agy99 GGAGGTGG-----AGAAG-----------AVLGGMGGLGG-DARLFGTGG Mflv_2178|M.gilvum_PYR-GCK GGTGADGGR--YAFGANWSLD----LP----VGGAGGAGGWANSIDGS-A TH_3810|M.thermoresistible__bu GGSGVDGVDVVGGNPDGGTP-------------GAHGESHTPGVYTDRQG MAB_4284c|M.abscessus_ATCC_199 HNQANIGTSTSAGGSAAVGGN----AG----LAGNAGLAGNAGLAGNAGL MAV_4827|M.avium_104 DSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQH MLBr_01556|M.leprae_Br4923 GGGNYRGGGVGALPGGGSGGFR------GRPGGGGHGGGGRPGQRGGAAG . * . Mvan_3865|M.vanbaalenii_PYR-1 AGGAGGAAVRTG---------------NGPDGQVYAGRGGDGGDAV---- MSMEG_3202|M.smegmatis_MC2_155 DGGRGGDGDGEG---------------PETAGSHGADGGNGGAGGV---- Mb2186c|M.bovis_AF2122/97 AGGAGGNG-SNG-----------------VTGVHGGNGGAGGAAGL---- Rv2162c|M.tuberculosis_H37Rv AGGAGGNG-SNG-----------------VTGVHGGNGGAGGAAGL---- MMAR_1208|M.marinum_M AGGNGGVG-GDGNAA-----------DSGLVGGAGGVGGAGGAAGL---- MUL_3672|M.ulcerans_Agy99 AGGTGGDN-SLG---------------LTGQGGQGGDAGAGGASGYG--- Mflv_2178|M.gilvum_PYR-GCK TGGNGGDG-GNG-----------------AFGGRGGNGGAGGSAYGRG-- TH_3810|M.thermoresistible__bu EDGEDGTGTG--------------------IGGRGGNGGSSSGTHP---- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAG-NAG---------------LAGNAGLAGNAGLAGNAGLAG-- MAV_4827|M.avium_104 LIVPTEQAPAPPPVQ-----------ASAPQPKISVPEPVAAPKPLSP-- MLBr_01556|M.leprae_Br4923 AFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGA Mvan_3865|M.vanbaalenii_PYR-1 ----------------------VGSGGQGGVGGDATS-----QGGPAT-- MSMEG_3202|M.smegmatis_MC2_155 ----------------------FGNGGRGGDGGDANNGTVGTRNGNAA-- Mb2186c|M.bovis_AF2122/97 ----------------------IGNGGAGGDGGNGGL-----SNTGAS-- Rv2162c|M.tuberculosis_H37Rv ----------------------IGNGGAGGDGGNGGL-----SNTGAS-- MMAR_1208|M.marinum_M ----------------------FGDGGAGGQGGDGAV-----SDALAASH MUL_3672|M.ulcerans_Agy99 ----------------------IGNGGAGGAAGDGGG-----AGSLGT-- Mflv_2178|M.gilvum_PYR-GCK ---------------------GITTGGNGGAGGHGSTG---AAGGRGG-- TH_3810|M.thermoresistible__bu ----------------------MAEDGEHVKALDGRPG---LDGGNGS-- MAB_4284c|M.abscessus_ATCC_199 ---------------------NAGLAGNAGLAGNAGLAGNAGLAGNAG-- MAV_4827|M.avium_104 ---------------------PVAAPLPAAPPPAAPPLPEAPPIPAAPPV MLBr_01556|M.leprae_Br4923 SLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQ Mvan_3865|M.vanbaalenii_PYR-1 -------------------SGGGGHGG----------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------AGKGGNGG----------------------- Mb2186c|M.bovis_AF2122/97 -------------------GGAGGAGG----------------------- Rv2162c|M.tuberculosis_H37Rv -------------------GGAGGAGG----------------------- MMAR_1208|M.marinum_M GGTGGDGGRSGWLSGNAGAGGAGGAGGSTNGIGNFAGNGGAGGN------ MUL_3672|M.ulcerans_Agy99 -------------------GGNGGSGGR---------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------DGASASGG----------------------- TH_3810|M.thermoresistible__bu ------------------HGGNGGHGGR---------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------LAGNAGLAGN---------------------- MAV_4827|M.avium_104 VPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPP------ MLBr_01556|M.leprae_Br4923 VVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLL Mvan_3865|M.vanbaalenii_PYR-1 ---SVAVFGDAGDGGFGGYAGS---------------------QNQATGR MSMEG_3202|M.smegmatis_MC2_155 ---STG-IGTGGAGGNGGKATG---------------------TNAAYGG Mb2186c|M.bovis_AF2122/97 ----AALIGNGGDGGHGGNG-----------------------GHGNSGG Rv2162c|M.tuberculosis_H37Rv ----AALIGNGGDGGHGGNG-----------------------GHGNSGG MMAR_1208|M.marinum_M -GGAAGLFGNGAAGGAGGAGGASQTFTGAGGAGGTGGAGGWLYGNGGAGG MUL_3672|M.ulcerans_Agy99 ---AALLYGVGRDGGAGGAG------------------------GDGVGS Mflv_2178|M.gilvum_PYR-GCK ----YAVGGNGGDGGRGGAGATG--------------------GTGGTGG TH_3810|M.thermoresistible__bu ----GGFLGIGGSGGWGGHGGNGG-------------------DTDADGG MAB_4284c|M.abscessus_ATCC_199 ----AGLAGNAGLAGNAGLAGNAG-----------------LAGNAGLAG MAV_4827|M.avium_104 -VRVPQPPSPPQVGGTVPQSPPQHQTP---------------PGEGTPPK MLBr_01556|M.leprae_Br4923 DTIRKANVREAEAGGITQHIGAYQVGVDLDGSE-RLITFIDTPGHEAFTA .* Mvan_3865|M.vanbaalenii_PYR-1 SGGDGGRG------------------GVLSGNGGDGGIG----------- MSMEG_3202|M.smegmatis_MC2_155 NGGNGGSG------------------LAGGGNGGDGGD------------ Mb2186c|M.bovis_AF2122/97 AGGAGGAG----------------GHVGLIGNGGNGGAG----------- Rv2162c|M.tuberculosis_H37Rv AGGAGGAGG----------AGGAGGHVGLIGNGGNGGAG----------- MMAR_1208|M.marinum_M AGGVGGAGIGTGGLGSNGGNGGTGGIGGLIGNGGAGGAGGAGSASGPSGY MUL_3672|M.ulcerans_Agy99 AGGSGGLG----------------GAAGLVDVGGDGGAG----------- Mflv_2178|M.gilvum_PYR-GCK AGGDGGRGGLLG------GHGGKGGNAGLGGNGGTGGTG----------- TH_3810|M.thermoresistible__bu NGGDGGNG-------------------GSAGRGGTGGLR----------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAAVAG-------NAAVAGNAAVAGNAAVGGVLNTG-------- MAV_4827|M.avium_104 PDGPGNYGG---------------GHVPTPGAGGSGGSG----------- MLBr_01556|M.leprae_Br4923 MRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKE . . . . . .. Mvan_3865|M.vanbaalenii_PYR-1 --------GYATSIG----------------------------------- MSMEG_3202|M.smegmatis_MC2_155 --------AQSSSNR----------------------------------- Mb2186c|M.bovis_AF2122/97 -----GNGGNDNSSTLADAGSGG--------------------------- Rv2162c|M.tuberculosis_H37Rv -----GNGGNDNSSTLADAGSGG--------------------------- MMAR_1208|M.marinum_M SGGNGGNGGNGGAAQLIGAGGGGGVAGVGGAGGTGAAAGVTGSAGASGVG MUL_3672|M.ulcerans_Agy99 -----GAGG----------GAGG--------------------------- Mflv_2178|M.gilvum_PYR-GCK -----GVGGDGGVGG----------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --VSGAIGGSSHVGGAINESLGGS-------------------------- MAV_4827|M.avium_104 -------GGHVPTPG----------------------------------- MLBr_01556|M.leprae_Br4923 GADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVG--------------- Mvan_3865|M.vanbaalenii_PYR-1 ------------------------------TGPAEGGAGGYGGSGGAFSR MSMEG_3202|M.smegmatis_MC2_155 ------------------------------ARPGQGGQAGRGGFGRDGKT Mb2186c|M.bovis_AF2122/97 ---------------------------AGAAGGNGGLFYGNGGVGGRGGN Rv2162c|M.tuberculosis_H37Rv ---------------------------AGAAGGNGGLFYGNGGVGGRGGN MMAR_1208|M.marinum_M GRLYSGNGIPDIFGRPLIGDGADGAPGTGQAGGDGGWLYGNGGNGGSGAA MUL_3672|M.ulcerans_Agy99 ------------------------------DGGAGAYLIGDGGDGGAGGH Mflv_2178|M.gilvum_PYR-GCK ---------------------------GILTATGVVGAGGSGGAGGTGGR TH_3810|M.thermoresistible__bu ------------------------------GVFGINGGNGRAGLGGRGXX MAB_4284c|M.abscessus_ATCC_199 ---------------------------GSVGGSTAVGGGAHTGVGGGVST MAV_4827|M.avium_104 ------------------------------AGGSGGSGGGHVPTPGTGGP MLBr_01556|M.leprae_Br4923 ------------------TNIEALLEAVLLTADAALDLRANSGMEAQGVA . Mvan_3865|M.vanbaalenii_PYR-1 G------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 G------------------------------------------------- Mb2186c|M.bovis_AF2122/97 G----------------------------------------GQAPTP--- Rv2162c|M.tuberculosis_H37Rv GGFSSAGTSGGDGGIGGAGGIGGLIGSGGGGGDG----GNGGQAPTP--- MMAR_1208|M.marinum_M GQAGGAGGAAGLIGNGGAGGTGGSGAAGGNGGAGGWLFGNGGNGGTGGDA MUL_3672|M.ulcerans_Agy99 G------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK G------------------------------------------------- TH_3810|M.thermoresistible__bu X------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGG--------------------------------------- MAV_4827|M.avium_104 G------------------------------------------------- MLBr_01556|M.leprae_Br4923 IEAHLDRGRGPVATVLVQRG------------------------------ Mvan_3865|M.vanbaalenii_PYR-1 ------------GDGGAGGN------------------------------ MSMEG_3202|M.smegmatis_MC2_155 ------------NPGNATDRSATRENVSNRV------------------- Mb2186c|M.bovis_AF2122/97 ---------GNAGDGGAGGNARLIGDGGRGG------------------- Rv2162c|M.tuberculosis_H37Rv ---------GNAGDGGAGGNARLIGDGGRGG------------------- MMAR_1208|M.marinum_M VAGLPGLNGGNGGNGGAGGAAGWWGHGGIGGQGGTGGAAGGFANTAPSTN MUL_3672|M.ulcerans_Agy99 ------------GDGGAG-------------------------------- Mflv_2178|M.gilvum_PYR-GCK ------------GDGGDGGQAGRGGAGGLAG------------------- TH_3810|M.thermoresistible__bu -------------XGGGVGAAVRSGNGVFSG------------------- MAB_4284c|M.abscessus_ATCC_199 ------ISESLGGSGSVGGSTAVGGGAHTGVG------------------ MAV_4827|M.avium_104 ------------GTGGSGGGHVPTPGAGTPG------------------- MLBr_01556|M.leprae_Br4923 --------TLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGF . Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------GLSATA MSMEG_3202|M.smegmatis_MC2_155 -----------TGRST---------------------------PTRSADK Mb2186c|M.bovis_AF2122/97 -----NGGEGGDGPPG---------------------------VKGDGGN Rv2162c|M.tuberculosis_H37Rv -----NGGEGGDGPPG---------------------------VKGDGGN MMAR_1208|M.marinum_M GLLGGNGGNGGDGGAGGWLFGDAGAGGQGGTGGAANDPLVGGSTGGSGGA MUL_3672|M.ulcerans_Agy99 ----------GDGNAG----------------------------SLAGGT Mflv_2178|M.gilvum_PYR-GCK ----------RSGADG---------------------------EAGDAGT TH_3810|M.thermoresistible__bu --------------------------------------------GGGTPS MAB_4284c|M.abscessus_ATCC_199 -----GGVSTGVGVGSHVG----------------------GGISESLGG MAV_4827|M.avium_104 ----------GSGGGHLP-------------------------FPGAGST MLBr_01556|M.leprae_Br4923 TSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSA Mvan_3865|M.vanbaalenii_PYR-1 PGNGGSGGRGGDGGPGGDGGLGGKGGVGSTN----------------NGA MSMEG_3202|M.smegmatis_MC2_155 AGSRTSSSSESNSESNSESSSKTSSKAGGTK----------------SSD Mb2186c|M.bovis_AF2122/97 GGNGGNAVVIGNGGNGGAG---GFGIPVGS-----------------GGA Rv2162c|M.tuberculosis_H37Rv GGNGGNAVVIGNGGNGGAG---GFGIPVGS-----------------GGA MMAR_1208|M.marinum_M GGNGGTAGLFGAGGAGGTGGTAGAGIAVGSNGGHGGQGGYGGWLGGSGGA MUL_3672|M.ulcerans_Agy99 GGNGGDAKVIGNGGNGGDGGVRFGGGANGS-----------------GGT Mflv_2178|M.gilvum_PYR-GCK GGRGGAGGSGGKGGISGTGTPGGAGQSGQSAT---------------GRS TH_3810|M.thermoresistible__bu AGFGVPTTIQFPAGSCTSRAVSREGIMPSSR-----------------AA MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVG-------GGISESLGGS MAV_4827|M.avium_104 PGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPG--------------GGL MLBr_01556|M.leprae_Br4923 LKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALR---------VID . . Mvan_3865|M.vanbaalenii_PYR-1 DGPDG------------------------GPAD----------------- MSMEG_3202|M.smegmatis_MC2_155 TKSGG------------------------GAAGTGSDSKDSE-------- Mb2186c|M.bovis_AF2122/97 GGSRG---------------------VLFGTPGANGADG----------- Rv2162c|M.tuberculosis_H37Rv GGSRG---------------------VLFGTPGANGADG----------- MMAR_1208|M.marinum_M GGTGGTGGSGDIYAGAGGTGGSGGAARLFGTGGTGGAGGVGGASDFQFAG MUL_3672|M.ulcerans_Agy99 GGAAG----------------------LLGSPGSDGTTV----------- Mflv_2178|M.gilvum_PYR-GCK GGAGG----------------------EGGAGGAGGTDD----------- TH_3810|M.thermoresistible__bu SARAG-----------------------AACASSTSRSRRSFCCSRA--- MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSS MAV_4827|M.avium_104 GGGGG-----------------HAPAPGGGLGGFGGGHSGGGLGGLGGGH MLBr_01556|M.leprae_Br4923 RGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIY * . Mvan_3865|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv2162c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1208|M.marinum_M SGGSGGTGGAAGWLIGNGGSGGQGGLAGTADPVTGLFGGTGGAGGAGGAA MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 INASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEH MAV_4827|M.avium_104 K------------------------------------------------- MLBr_01556|M.leprae_Br4923 QAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVV Mvan_3865|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- Mb2186c|M.bovis_AF2122/97 -------------------------------------------------- Rv2162c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1208|M.marinum_M GWLYGAGGSGGAGGAGTASVYPGLSGGNGGNGGNGGAAQVIGNGGSGGTA MUL_3672|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 H------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIK Mvan_3865|M.vanbaalenii_PYR-1 ----------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 ----------------------------------------- Mb2186c|M.bovis_AF2122/97 ----------------------------------------- Rv2162c|M.tuberculosis_H37Rv ----------------------------------------- MMAR_1208|M.marinum_M GTGGAGGPDDPPNNIPAGTDGQDGAGGAGGSGGLVFGDSGG MUL_3672|M.ulcerans_Agy99 ----------------------------------------- Mflv_2178|M.gilvum_PYR-GCK ----------------------------------------- TH_3810|M.thermoresistible__bu ----------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------- MAV_4827|M.avium_104 ----------------------------------------- MLBr_01556|M.leprae_Br4923 EGDVIESYELVEKQRA-------------------------