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ANIISNGPDGDAGATGAQGSQGATGAAGAMANCNWIDDDCATRGGTGGTGGNGGPGGAGGPGGHGGVIDF EVETFMDGVTLQAKGGRGGNGGHGGAGGTGGTGGKGGDGDDCEFGRTGGNGGTGGRGGDGNFAGTGGNGG AILVKCQHDLSLGTHPMDVSAGTGGNGGIGGGGGGGGSVGANGATTGVFSSSSDCSGPGPQPNPGSPGDP GTSVAVSGAQGNPGQAQFLIVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0321c | - | - | 100% (233) | hypothetical protein MAB_0321c |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-15 | 27.20% (239) | hypothetical protein MAB_4284c |
| M. abscessus ATCC 19977 | MAB_0010c | - | 4e-13 | 31.86% (204) | hypothetical protein MAB_0010c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | 5e-36 | 41.38% (232) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 8e-39 | 43.95% (223) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3344c | PE_PGRS49 | 7e-38 | 40.16% (249) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 0.0001 | 33.33% (117) | translation initiation factor IF-2 |
| M. marinum M | MMAR_4995 | - | 5e-38 | 42.92% (226) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 6e-14 | 38.82% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-28 | 38.40% (237) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-20 | 34.09% (220) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3318 | - | 3e-34 | 41.63% (233) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-38 | 42.08% (240) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2667c|M.bovis_AF2122/97 -----------------------------------MSFVIAVPEALTMAA
MUL_3318|M.ulcerans_Agy99 -----------------------------------MSYLAIAPEIVAAAA
MMAR_4995|M.marinum_M -----------------------------------MSYLIVAPEAMTAAA
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------------------MVTFGGGATPTPTSLGAAA
Mvan_1264|M.vanbaalenii_PYR-1 MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASL
MSMEG_0868|M.smegmatis_MC2_155 -MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPE
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------MNIVLGVSMAPSSIQMVV
MLBr_01556|M.leprae_Br4923 ----------------------MAGKARVHELAKELGVTSKEVLARLNEQ
Mb2667c|M.bovis_AF2122/97 SDLANIGSTINAANAAAALPTTGVVAA-AADEVSAAVAALFGSYAQSYQA
MUL_3318|M.ulcerans_Agy99 ADMDGIGSPITAANAAAAIPTSAIAAA-AADEISAAIAELFGNHAQQYQA
MMAR_4995|M.marinum_M GDLAGIGSSVAAANAAAAGPTTAMLTA-AADEVSTAIAAFFSAHAADYQR
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VDLSGTSCGLICNGQDGTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGL
Mvan_1264|M.vanbaalenii_PYR-1 VDLSGTSCGLICNGQDGTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGL
MSMEG_0868|M.smegmatis_MC2_155 SPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ
MLBr_01556|M.leprae_Br4923 GEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESL
Mb2667c|M.bovis_AF2122/97 FGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLG
MUL_3318|M.ulcerans_Agy99 LSAQMARFHDQFVRSLSGAAQTYARAEATGAAPLQPVLDLINGPTQALLG
MMAR_4995|M.marinum_M LAGQAAALHTQLERVLSAGAVAYAAAETTGTSPLQLAINAVSAPAQSLLA
Rv3344c|M.tuberculosis_H37Rv -------------------------AQASPAA------------------
Mflv_5091|M.gilvum_PYR-GCK FGGNGGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG
Mvan_1264|M.vanbaalenii_PYR-1 FGGNGGNGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG
MSMEG_0868|M.smegmatis_MC2_155 TSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 LSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG
MLBr_01556|M.leprae_Br4923 DQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAP
Mb2667c|M.bovis_AF2122/97 RP------------------------------------------------
MUL_3318|M.ulcerans_Agy99 RP------------------------------------------------
MMAR_4995|M.marinum_M RP------------------------------------------------
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK APG-----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 APG-----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 APTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 YER-----------------------------------------------
MLBr_01556|M.leprae_Br4923 PAG-----------------------------------------------
Mb2667c|M.bovis_AF2122/97 -----------------------------------------LIGNGANGA
MUL_3318|M.ulcerans_Agy99 -----------------------------------------LIGNGTSGA
MMAR_4995|M.marinum_M -----------------------------------------IIGNGAN-A
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------VAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------VAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 PTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-G
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------------TAVL
MLBr_01556|M.leprae_Br4923 ------------------------------------------QPSEQPGV
Mb2667c|M.bovis_AF2122/97 DGTGAPGGPGGLLLGNGGNG-GSGAPGQPGGAGGDAGLIGNGGTGGKGGD
MUL_3318|M.ulcerans_Agy99 LGTGQAGGDGGLLIGNGTSG-ALGT-GQAGGDGG--LLIGNGGAGGSGAA
MMAR_4995|M.marinum_M TTPGGNGGDGGWLFGSGGNG-AAGAAGQAGGSGGSAGLLGNGGAGGAGGT
Rv3344c|M.tuberculosis_H37Rv --HGGSGGAG----GNGGAG-SAGN-GGAGGAGG------NGGAGGNGGG
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATG-AAGAAGAAGAAGAAGAVGSAGAAGEAGET
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATG-AAGAAGAAGAAGKAGAVGSAGTAGSAGAP
MSMEG_0868|M.smegmatis_MC2_155 TADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWA
TH_3810|M.thermoresistible__bu ------------VDGDGGSG------GRTG-------LFSKLSRGGDGGD
MAB_0321c|M.abscessus_ATCC_199 ---------------------MAN-------------IISNGPDGDAGAT
MAV_4827|M.avium_104 LVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLE
MLBr_01556|M.leprae_Br4923 PLPGQQGTPAAPHPGHPGMP-TGPHPGPAPKPGGRPPRVGNNPFSSAQSV
.
Mb2667c|M.bovis_AF2122/97 G----------------------------LVGSGAAGGVGGRGGWLLGNG
MUL_3318|M.ulcerans_Agy99 G----------------------------QAGG--AGGAGGAAG-LIGSG
MMAR_4995|M.marinum_M GGARGGNGGSGGLLFGGGGIGGTGGTGAAGAGMGGMGGNGGSGSWLIGGG
Rv3344c|M.tuberculosis_H37Rv G----------------------------DAGNAGSGGNGGKGGDGVGPG
Mflv_5091|M.gilvum_PYR-GCK G-------------------------TWGNAGLPGKAGDAGGAG-AVGAA
Mvan_1264|M.vanbaalenii_PYR-1 G-------------------------VWGNAGLPGAAGAAGGAG-AIGTA
MSMEG_0868|M.smegmatis_MC2_155 G--------------LDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDG
TH_3810|M.thermoresistible__bu G----------------------------------------------GLG
MAB_0321c|M.abscessus_ATCC_199 G-------------------------------------------------
MAV_4827|M.avium_104 S----------------------------LPGGLLLVGSGVDVAPLKQVL
MLBr_01556|M.leprae_Br4923 AR------------------------PIPRPPAPRPSASPSSMSPRPGGA
.
Mb2667c|M.bovis_AF2122/97 GTGGAGGAAGATL-VGGTGGVGGAT-GLIGSGGFGGAGGAAAGVGTTG--
MUL_3318|M.ulcerans_Agy99 GAGGIGG-------TGAAGGKGGNA-VLFGAGGNGGIGGTGA-VGGTG--
MMAR_4995|M.marinum_M GAGGAGGIGGTGGGTGGVGGTGGDAGWLVGAGGSGGSGGIGATGTGSG--
Rv3344c|M.tuberculosis_H37Rv STGGAGG-------KGGAGANGGSS-NGNARGGNAGNGGHGG-AGGSG--
Mflv_5091|M.gilvum_PYR-GCK GAAGTVGTAGATGGTGTGANGGAGGVGGVGGTGAAGAAGGAGGLGETG--
Mvan_1264|M.vanbaalenii_PYR-1 GVAGAAGTAGATGGTGVGGNGGAGQAGGIGGTGAAGAAGQAGTAGETG--
MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNG
TH_3810|M.thermoresistible__bu GNGGHGG--------------GTGIISLLSLAGNGGNGGNGYRTTDNN--
MAB_0321c|M.abscessus_ATCC_199 ------------------------------AQGSQGATGAAGAMANCN--
MAV_4827|M.avium_104 QTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTG--
MLBr_01556|M.leprae_Br4923 VGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGG--
. .
Mb2667c|M.bovis_AF2122/97 --------------------GVGGSGGVGG---VFGNGGFGGAG-GLG--
MUL_3318|M.ulcerans_Agy99 --------------------AVGGAGGNGGF--LFGHGGDGGTG-GTGAS
MMAR_4995|M.marinum_M --------------------GAAGNGGNGGAGGLFMNGGDGGAG-GQGGD
Rv3344c|M.tuberculosis_H37Rv --------------------DTGGAGGAGG------QGGFGGTG-GSG--
Mflv_5091|M.gilvum_PYR-GCK --------------------TTGGAGGVGGQG---TAGGTGGVG-GIGGA
Mvan_1264|M.vanbaalenii_PYR-1 --------------------VTGGVGGIGGQG---TEGGTGGVG-GVGGV
MSMEG_0868|M.smegmatis_MC2_155 GFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------AVDQYSLPDYLYVPVDPEPGDDELAYSAV
MLBr_01556|M.leprae_Br4923 ---------------------SGGFRGRPGGGGHGGGGRPGQRGGAAGAF
Mb2667c|M.bovis_AF2122/97 -AAGGVGGAASYFGTGGGGGVGGDG------APGGDGGAG-PLLIGNGGV
MUL_3318|M.ulcerans_Agy99 AAAGANGGAGQTGLAGTDGGTGGAS------GEGGAGGKG-GLLFGAGGE
MMAR_4995|M.marinum_M GAAGAAAAAAG--GTGGDGGLGGNG------GAGGAGGGG-PVLFGHGGA
Rv3344c|M.tuberculosis_H37Rv --------------SGIGGGAGGNG------GNGGAGGTG-VVLGGKGGD
Mflv_5091|M.gilvum_PYR-GCK GSTGAVGGVGGKGIQGGQGLQGGKG------GDGGAGGKG-GDADSMGSA
Mvan_1264|M.vanbaalenii_PYR-1 GATGGAGGVGGKGIQGGQGLQGGQG------GDGGTGGTG-GDATSMGEA
MSMEG_0868|M.smegmatis_MC2_155 ILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGST
TH_3810|M.thermoresistible__bu ---------------ALDGGHGGNG-----------GNVGFFSLFNLGGA
MAB_0321c|M.abscessus_ATCC_199 ---------------WIDDDCATRG---------GTGGTG-----GNGGP
MAV_4827|M.avium_104 GEEDAESPTVVIEKLFLPEDSEPRR------RPVLLVGSG-LAVVGISAV
MLBr_01556|M.leprae_Br4923 GRPGGAPRRGRKSKRQKRQEYDSMQAPVVG-GVRLPHGNGETIRLARGAS
. * .
Mb2667c|M.bovis_AF2122/97 GGLGGAGAAG----------------------------------------
MUL_3318|M.ulcerans_Agy99 GGAGGTGGAG----------------------------------------
MMAR_4995|M.marinum_M GGLGGQGGTGGIGGTGGAGTTSIAAGTGGNGGAGGAAGGGGTAGAAGPLT
Rv3344c|M.tuberculosis_H37Rv GGNGDHGGPA----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNG----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GATGGKGGNG----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 AEGTATGGDGGHSTGTG---------------------------------
TH_3810|M.thermoresistible__bu GGWGGSGVDG----------------------------------------
MAB_0321c|M.abscessus_ATCC_199 GGAGGPGGHG----------------------------------------
MAV_4827|M.avium_104 LALEIALAIG----------------------------------------
MLBr_01556|M.leprae_Br4923 LSDFAEKIDAN---------------------------------------
.
Mb2667c|M.bovis_AF2122/97 ---------------------------------------------GNGGA
MUL_3318|M.ulcerans_Agy99 ---------------------------------------------GTGGA
MMAR_4995|M.marinum_M NAGLAGGFGTGGTGGTGGTGGAGAPGIDGAALGEGGTNGYIGGNGGNGGA
Rv3344c|M.tuberculosis_H37Rv ---------------------------------------------TNPGS
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------------GNGGR
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------------GNGGR
MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------IGGNGGI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------IRTTGT
MLBr_01556|M.leprae_Br4923 ---------------------------------------------PAALV
Mb2667c|M.bovis_AF2122/97 GGMLLGDGGAG---------------------------GQGGPAVAGVLG
MUL_3318|M.ulcerans_Agy99 GGDGLAATTAG---------------------------GTGGNAGD---G
MMAR_4995|M.marinum_M GGAALGGGAAGDGGQGGHGGAGGMGGAGANGITGGGVTGAGGNGGDGGQG
Rv3344c|M.tuberculosis_H37Rv G----SRGGAG---------------------------GSGGNGGAG--G
Mflv_5091|M.gilvum_PYR-GCK GGLFGKGGNAGNG-------------------------ADGGTGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GSLFGRGGNAGNG-------------------------GNGGTGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 GSVYAYGNNGAVSG-----------------------TATGGRGGDGIDG
TH_3810|M.thermoresistible__bu --VDVVGGNPD-----------------------------GGTPGAH---
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 VALQPTPNQHLIVP------------------------TEQAPAPPPVQA
MLBr_01556|M.leprae_Br4923 QALFNLGEMVTAT-------------------------QSVGDETLELLG
Mb2667c|M.bovis_AF2122/97 GMPGAG--------------------------------------------
MUL_3318|M.ulcerans_Agy99 GEGGAG--------------------------------------------
MMAR_4995|M.marinum_M GEPGTGGAAGSGGGGQTGSLGIGGTGGHGGAGGDGTPGGNGAAGPTAGTG
Rv3344c|M.tuberculosis_H37Rv NATGSG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTG--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGY
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 SAPQPK--------------------------------------------
MLBr_01556|M.leprae_Br4923 SEMNYN--------------------------------------------
Mb2667c|M.bovis_AF2122/97 ---------------------------------------GNGGNANWFGS
MUL_3318|M.ulcerans_Agy99 ---------------------------------------GNAG------A
MMAR_4995|M.marinum_M DPGVDGGAGGNGGAGGQGGSNGTGGDGGTGGSGATGGDGGTGGAGTATDA
Rv3344c|M.tuberculosis_H37Rv ---------------------------------------GKGG------A
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------GAGG------T
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------GNGG------T
MSMEG_0868|M.smegmatis_MC2_155 GPTTGGKASG-------------------------TAKAGHGGKASDGGK
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------VQVVSPEDEDRELLEPFD
Mb2667c|M.bovis_AF2122/97 GGAGGQGGT----------GLAGTNGVNPGSIANPNTGANGTD-------
MUL_3318|M.ulcerans_Agy99 GGAGGQG------------GLFG------------NAGTTG---------
MMAR_4995|M.marinum_M GGTGGQGGVGGAGGAPGAAGLAGTGGQAGNEGVGGNGGQGGHGGAGGNGV
Rv3344c|M.tuberculosis_H37Rv GGNGGDG----------------------------SFGATS---------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGIG-------------------------GAGSTG---------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGIG-------------------------GAGSTG---------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKAN---------
Mb2667c|M.bovis_AF2122/97 -----------------------NSGNGNQTGGNGGPGPAGGVGEAG---
MUL_3318|M.ulcerans_Agy99 ------------------------------AGGDGGNGGNGGLAGNG---
MMAR_4995|M.marinum_M DGADANVFTGDNGGDGTAGGKGGDGGAGGAAGANGGTGGGGGIGGGG---
Rv3344c|M.tuberculosis_H37Rv --------------------------------GPASIGVTGAPGGNG---
Mflv_5091|M.gilvum_PYR-GCK -----------------------------GTGGTGGTGGTGGTGGTG---
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------GTGGTGGTGGTGGTGGTG---
MSMEG_0868|M.smegmatis_MC2_155 G--------------SITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
TH_3810|M.thermoresistible__bu -----------------------------------GESHTPGVYTDR---
MAB_0321c|M.abscessus_ATCC_199 ----------------------------------GVIDFEVETFMDG---
MAV_4827|M.avium_104 ---------------------------ISVPEPVAAPKPLSPPVAAP---
MLBr_01556|M.leprae_Br4923 ----------------------------VREAEAGGITQHIGAYQVG---
Mb2667c|M.bovis_AF2122/97 ----------GVGGQGGLGESLDGNDGTGGKGGAG-------------GT
MUL_3318|M.ulcerans_Agy99 ----------GAGGNG---------DASNPNGGTG-------------GN
MMAR_4995|M.marinum_M ----------GVGGDGGNGGSGNTGTSSAPAGGTGGIGGTGAD----GGA
Rv3344c|M.tuberculosis_H37Rv ----------GKGGAG----------GSNPNGSGG---------------
Mflv_5091|M.gilvum_PYR-GCK ----------GTGGTGGTG-------GTGGKGGTGG-----------TGG
Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTG-------GTGGKGGTGG-----------TGG
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------LPAAPPPAAPP--------------
MLBr_01556|M.leprae_Br4923 ---------VDLDGSERLITFIDTPGHEAFTAMRARG-----------AK
Mb2667c|M.bovis_AF2122/97 AGTDGGAGGAGGAGGIGETDGSAGGVATGGEG-------------GDGAT
MUL_3318|M.ulcerans_Agy99 AANPG-AGGAGGAGGNGSRTGAPG------------------------TT
MMAR_4995|M.marinum_M GGNGGAAGGAGGTGGQGGTGGGAGKGGTGGAGGAAVTPGLGIGDEPAGGT
Rv3344c|M.tuberculosis_H37Rv ---DGGKGGNGGAGGNGGSIGANS-----------------------GIV
Mflv_5091|M.gilvum_PYR-GCK AGGTGGDGGTGGTGGTGGTGGTGGTGGTGGAG---------------DGT
Mvan_1264|M.vanbaalenii_PYR-1 DGGTGGTGGTGGTGGTGGTGGTGGTGGTGGAG---------------DGL
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGG------------VSEGE
TH_3810|M.thermoresistible__bu -------QGEDGEDGTG---------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 LPEAPPIPAAPPVVPVPVVVPPVPVP--------------------VPVR
MLBr_01556|M.leprae_Br4923 ATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVN---------KID
Mb2667c|M.bovis_AF2122/97 GGVD--GGVGGAGGKGGQGHNTGVGDA-----FGGDGGIGGDGNG-----
MUL_3318|M.ulcerans_Agy99 GNTP--TTAAGHGGKGGDGFNPATSGQ-----DGGSGGKGGD--------
MMAR_4995|M.marinum_M GGTGGHGGTGGHGGTGGAAGNGGAGGAGGQAGDGGSGGEGGDGGTGAQGT
Rv3344c|M.tuberculosis_H37Rv GGSG---GAGGAGGAGGNGSLSSGEGG-----KGGDGGHGGDGVG-----
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGQGGQGGQGGTGGTGGQ------GGLGGGGGTGGQ-----
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGFGGQGGQGGTGGTGGQ------GGLGGVGGTGGT-----
MSMEG_0868|M.smegmatis_MC2_155 GGTGGHGGDGGRGGDGALGGNGGTGGVG--LGNGGKGGNGGNGGNG----
TH_3810|M.thermoresistible__bu ------TGIGGRGGNGGSSSGTHPMAE------DGEHVKALDGRP-----
MAB_0321c|M.abscessus_ATCC_199 ------VTLQAKGGRGGNGGHGGAGGT------GGTGGKGGDGDD-----
MAV_4827|M.avium_104 IPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ-----
MLBr_01556|M.leprae_Br4923 KEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLT
Mb2667c|M.bovis_AF2122/97 -----------------------------------ALGAAGGNGGTGGAG
MUL_3318|M.ulcerans_Agy99 ----------------------------------------------AGQF
MMAR_4995|M.marinum_M TVSLPGSGGNAGNGGNAGGGGVGGTGGAGATGAPAGRGGTGGNGGNAGAG
Rv3344c|M.tuberculosis_H37Rv ---------------------------------------------GNSSV
Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------GGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------GGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------GTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu ----------------------------------------------GLDG
MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------------CEFG
MAV_4827|M.avium_104 ----------------------------------------------SPPQ
MLBr_01556|M.leprae_Br4923 ---------------------------------------ADAALDLRANS
Mb2667c|M.bovis_AF2122/97 GNGGRGGM-----------LIGNGGAG------------GAGGTGGTGGG
MUL_3318|M.ulcerans_Agy99 GNGGNG---------------GNGAAG------------DAAGSGHTGGN
MMAR_4995|M.marinum_M GKGGAGAFGGAGSSPGFLSPAGNGGAGGDAGTAAAGGDGGAGGAGPSGGN
Rv3344c|M.tuberculosis_H37Rv TQGGSG---------------GGGGAG------------GAGGSGFFGGK
Mflv_5091|M.gilvum_PYR-GCK GQGGTG---------------GTGGTG------------GTGGTGGAGGD
Mvan_1264|M.vanbaalenii_PYR-1 GQGGTG---------------GTGGTG------------GTGGTGGAGGD
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGD--------ADGHRGGKGGD
TH_3810|M.thermoresistible__bu GNGSHG---------------GNGGHG------------GRGGFLGIGGS
MAB_0321c|M.abscessus_ATCC_199 RTGGNG---------------GTGGRG------------GDGNFAGTGGN
MAV_4827|M.avium_104 HQTPPG----------------EGTPP------------KPDGPGNYGGG
MLBr_01556|M.leprae_Br4923 GMEAQG---------VAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDA
* *.
Mb2667c|M.bovis_AF2122/97 GA-----------------AGFAGGVGG----------------------
MUL_3318|M.ulcerans_Agy99 GG-----------------AGGGGGNAG----------------------
MMAR_4995|M.marinum_M GG-----------------TGGNGGHGGNGGNGAEGAIGAQFVPASSLPT
Rv3344c|M.tuberculosis_H37Rv GG-----------------FGGDGGQGG----------------------
Mflv_5091|M.gilvum_PYR-GCK GG-----------------LGGLGGFGG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 GG-----------------LGGLGGFGG----------------------
MSMEG_0868|M.smegmatis_MC2_155 GGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQA
TH_3810|M.thermoresistible__bu GG-----------------WGGHGGNGG----------------------
MAB_0321c|M.abscessus_ATCC_199 GG-----------------AILVKCQHD----------------------
MAV_4827|M.avium_104 HVP----------------TPGAGGSGG----------------------
MLBr_01556|M.leprae_Br4923 YGR----------------VRRMVDEHG----------------------
.
Mb2667c|M.bovis_AF2122/97 --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4995|M.marinum_M PSGGAGGDGGNGSNGGAPGAGGSAGAGTGGSTGGQGTGGDGGNGGNGGNG
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 NPQASG--------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4995|M.marinum_M ADGANAVNIAFTPNEPQATAGNPGGSGITGEIGGSGTNGSPATLPTTQVQ
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------TATDGHGGSGI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------------------------------VDIEAALPSSPVQ
Mb2667c|M.bovis_AF2122/97 AGGEGLTDGAGT-------------AEGGTGGLGGLGGVGGTGGMG----
MUL_3318|M.ulcerans_Agy99 QFGEPGTGGSG--------------GNGGKGGDGAAGGNGGTGGIG----
MMAR_4995|M.marinum_M QGGDGGAGGTGTNAANNE---VATGGEGGTGGTGSAGGPGGDGGVGGDAS
Rv3344c|M.tuberculosis_H37Rv --------------------------PNGGGTVGTVAGGGGNGGVG----
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGG-------------PGGSTGGAGGAGGQAGTAGKGG---
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGG-------------PGGSTGGAGGAGGQAGVAGKGG---
MSMEG_0868|M.smegmatis_MC2_155 NGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNT
TH_3810|M.thermoresistible__bu -------------------------DTDADGGNGGDGGNGGSAGRG----
MAB_0321c|M.abscessus_ATCC_199 -------------------------LSLGTHPMDVSAGTGGNGGIGG---
MAV_4827|M.avium_104 -------------------------SGGGHVPTPGAGGSGGSGG------
MLBr_01556|M.leprae_Br4923 VIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRIS---
. .
Mb2667c|M.bovis_AF2122/97 --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4995|M.marinum_M ETGTDGVAVGGQGGQGGAGGQFGGGGNGGDGGNVTAGSAGSTAGNGGNGG
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TAN-----------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4995|M.marinum_M NANNGTIEGSPAGGNGSAGGDGGDGGDVASGATGTAGTGGTGGAGNDGTI
Rv3344c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------AANPG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 --GSGGVGGNGGAAGSLIGLGGGGG--------------------AGGVG
MUL_3318|M.ulcerans_Agy99 --GTGGIGGDG-RNGSTGAIGGNGG--------------------TGGTG
MMAR_4995|M.marinum_M NAGTGGNGGAGGRAGSGGANGGNGG--------------------TGGTG
Rv3344c|M.tuberculosis_H37Rv -----GRGGDG-------VFAGAGG--------------------QGGLG
Mflv_5091|M.gilvum_PYR-GCK LFGGSGSAGKAGATGAAGASGGKGA--------------------QGATG
Mvan_1264|M.vanbaalenii_PYR-1 LFGGSGSAGTAGVTGASGASGGKGA--------------------QGATG
MSMEG_0868|M.smegmatis_MC2_155 SATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKG
TH_3810|M.thermoresistible__bu --------GTGGLRGVFGINGGNGR---------------------AGLG
MAB_0321c|M.abscessus_ATCC_199 --------------------GGGGG---------------------GSVG
MAV_4827|M.avium_104 ---------------GHVPTPGTGG--------------------PGGTG
MLBr_01556|M.leprae_Br4923 -LEDLDSALKETSQLNLILKGDNAG---------------TVEALEEALM
. . .
Mb2667c|M.bovis_AF2122/97 GTGGIGGIGGAGGNGGAGGAGTTTG--GGATIGGGGGTGGVG--------
MUL_3318|M.ulcerans_Agy99 GTGGTGGKSLGNLPSGDGGVG------GNAGTGGNGGNATDG--------
MMAR_4995|M.marinum_M GDGGKGGGGAVGGSGGDGGDGGINNGAGANGNGGGGGTGGTG--------
Rv3344c|M.tuberculosis_H37Rv GQGGNGG----GSTGGNGGLG---------GAGGGGGNAPDG--------
Mflv_5091|M.gilvum_PYR-GCK AQGATGAQGATGATGAAGKAGATGAAGAAGAAGSAGTTGAQG--------
Mvan_1264|M.vanbaalenii_PYR-1 AQGATGAQGATGATGASGAQGSAGSAGSAGVAGSAGTTGAQG--------
MSMEG_0868|M.smegmatis_MC2_155 GEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGG
TH_3810|M.thermoresistible__bu GRGXXXX---GGGVGAAVRSG-------NGVFSGGGGTPSAG--------
MAB_0321c|M.abscessus_ATCC_199 ANGATTG--VFSSSSDCSGPG-----------------------------
MAV_4827|M.avium_104 GSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTP-------
MLBr_01556|M.leprae_Br4923 GIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEG------
.
Mb2667c|M.bovis_AF2122/97 -----------------------GAGGTGGTGGAG--GTTGGSGGA--GG
MUL_3318|M.ulcerans_Agy99 -----------------------GAGGKGGDGAAG--GTGGNAGEF--QS
MMAR_4995|M.marinum_M -----------------------SIGAAGGNGGQG--GSGGAAGSG--GG
Rv3344c|M.tuberculosis_H37Rv -----------------------GFGGNGGKGGQG--GIGGGTQSA--TG
Mflv_5091|M.gilvum_PYR-GCK -----------------------SAGTNGANGANGSQGAAGKAGATGTTG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------SAGTNGANGANGSQGAAGKAGATGTTG
MSMEG_0868|M.smegmatis_MC2_155 FSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKI
TH_3810|M.thermoresistible__bu ------------------------FGVPTTIQFP----------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------GAGTPG---------------------
MLBr_01556|M.leprae_Br4923 ---------------------KATELASREGVEIRYYLVIYQAIDDIEKA
Mb2667c|M.bovis_AF2122/97 LIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGG--QGGDFALGG
MUL_3318|M.ulcerans_Agy99 LLGIS----------------KGGDGGTGGDGGTGTPVG--ADG---LAG
MMAR_4995|M.marinum_M TAGNGGAGGVGGAGGTGGVGGGGGDGGAGALAGTGGTGG--SGGTGGASG
Rv3344c|M.tuberculosis_H37Rv LGGDGG---------------DGGDGGNGGNSG-AKAGG--AGG----KG
Mflv_5091|M.gilvum_PYR-GCK ATGAAGEDGDAGSGGSGINGGAGGAGGAGGEGGEGGDGG--KGGAGAEGG
Mvan_1264|M.vanbaalenii_PYR-1 ATGAAGDAGDPGSEAVDINGGAGGAGGAGGEGGEGGAGG--AGGDGSEGG
MSMEG_0868|M.smegmatis_MC2_155 ANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGG
TH_3810|M.thermoresistible__bu ----------------------AGSCTSRAVSREGIMPS----------S
MAB_0321c|M.abscessus_ATCC_199 ---------------------PQPNPGSPGDPGTSVAVS---------GA
MAV_4827|M.avium_104 ----------------------GGLGGFGGGHAPAPGGG--------LGG
MLBr_01556|M.leprae_Br4923 LRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLL
.
Mb2667c|M.bovis_AF2122/97 NGGAGGAGG--SPG-GSSGIQGNMGPPGTQGADG----------------
MUL_3318|M.ulcerans_Agy99 TGGAGGFGI--FPG-GQTGQNGTDSKAG----------------------
MMAR_4995|M.marinum_M AGGSGGGGG--LSGSGQSGANGGTGGASQEGQDGQASTDSDGGAGGAGGT
Rv3344c|M.tuberculosis_H37Rv QAGQPNSGT--EPGFGGDGGLGGAGATP----------------------
Mflv_5091|M.gilvum_PYR-GCK AGGGGGAGGSGAGGAGGAGGSGGSGGSGGSGGSGGAAGDSDD--------
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAGGSGTGGAGGAGGSGGSGGSGGAGGSGGAAGDSD---------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGAD
TH_3810|M.thermoresistible__bu RAASARAGAACASSTSRSRRSFCCSRA-----------------------
MAB_0321c|M.abscessus_ATCC_199 QGNPGQAQFLIVP-------------------------------------
MAV_4827|M.avium_104 GGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------------------
MLBr_01556|M.leprae_Br4923 RDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYE
Mb2667c|M.bovis_AF2122/97 --------------
MUL_3318|M.ulcerans_Agy99 --------------
MMAR_4995|M.marinum_M GGSGGAAGAGGQA-
Rv3344c|M.tuberculosis_H37Rv --------------
Mflv_5091|M.gilvum_PYR-GCK --------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------
MSMEG_0868|M.smegmatis_MC2_155 GTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu --------------
MAB_0321c|M.abscessus_ATCC_199 --------------
MAV_4827|M.avium_104 --------------
MLBr_01556|M.leprae_Br4923 LVEKQRA-------