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M. marinum M MMAR_2100 (-)

annotation: PE-PGRS family protein
coordinates: 2524988 - 2529181
length: 1397
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 Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2100--100% (1397)PE-PGRS family protein
M. marinum MMMAR_2656-0.055.72% (1468) PE-PGRS family protein, PE_PGRS50
M. marinum MMMAR_1442-0.055.66% (1450) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3538PE_PGRS540.053.28% (1492) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-17946.22% (846) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.050.27% (1637) PE-PGRS family protein
M. leprae Br4923MLBr_01183-5e-1439.13% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-5436.05% (441) hypothetical protein MAB_4284c
M. avium 104MAV_4827-3e-2542.11% (171) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-16540.02% (1092) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-9e-4543.94% (289) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.049.21% (1136) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-17746.86% (828) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQV
Rv3508|M.tuberculosis_H37Rv         -----------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQV
MUL_4367|M.ulcerans_Agy99           -----------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGV
MMAR_2100|M.marinum_M               -----------MSFVSVTPEMVVAAASDLSGINSAIAQANSVAAAATTTV
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------MMFLAPPGGPGPISAAIQL
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGA
                                                                                      

Mb3538|M.bovis_AF2122/97            LAAGADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS
Rv3508|M.tuberculosis_H37Rv         LAAGADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS
MUL_4367|M.ulcerans_Agy99           LPAAGDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ
MMAR_2100|M.marinum_M               LPAAADEVSAAIAALFGTHAQQYQAISAELAAFHDRFVQSLNTGAGSYLR
Mflv_5091|M.gilvum_PYR-GCK          ------------MVTFGGGA------TPTPTSLGAAAVDLSGTSCG----
Mvan_1264|M.vanbaalenii_PYR-1       TSTGSEATEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG----
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      QVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPD----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR---
                                                                                      

Mb3538|M.bovis_AF2122/97            AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT
Rv3508|M.tuberculosis_H37Rv         AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT
MUL_4367|M.ulcerans_Agy99           AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA
MMAR_2100|M.marinum_M               AEAAN---------------AEQGLLGLVNAPTQALFGRPLIGDGANGAP
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQD---
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------GPSILS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------DALAARRIDNVM
                                                                                      

Mb3538|M.bovis_AF2122/97            TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
Rv3508|M.tuberculosis_H37Rv         TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG--
MMAR_2100|M.marinum_M               GSGQAGGAGGLLYGNGGAGG-SGGVGQAGGAGGAAGLIGSGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG--
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG--
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGG---LIWGGGGAGG
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGG---LIWGGGGAGG
MUL_4367|M.ulcerans_Agy99           ---------------VGAAG----MTGGSGGAGGGGG---WLWGAGGSGG
MMAR_2100|M.marinum_M               G-TGGAGGAGGWLYGNGGAG----GVGGAGAVGGAGGN-TWLWGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ------------------------LGGGNGGNGGNAGA-FALFGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------LGSGDGGNGGDAGL-FSLFGRGGNGG
MSMEG_0868|M.smegmatis_MC2_155      -----------LDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGG
TH_3810|M.thermoresistible__bu      -------------------------------------------VD----G
MAB_4284c|M.abscessus_ATCC_199      -----------------------PLLDLSFGDLQFGNRDTTAIGDGAVAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------KQQIRAESYGDAAGQLSAMVAGLEKL
                                                                                      

Mb3538|M.bovis_AF2122/97            VGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGG
Rv3508|M.tuberculosis_H37Rv         VGGAGGGTGGAGGRAELLFGAGGAGGAG---TDGGPGATGGTGGHGGVGG
MUL_4367|M.ulcerans_Agy99           AAGAGG-----------------------------------------SGG
MMAR_2100|M.marinum_M               SGGVGSGSGGAGGSGGWLYGNGGAGGTG-----GVADGVGEGGGHGGAGG
Mflv_5091|M.gilvum_PYR-GCK          NGGVGV--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       NGGVGI--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGTGG--------------------------------------------
TH_3810|M.thermoresistible__bu      DGGSGG--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSNSGP-------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ESLPGG--------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            DGGWLAPGGAGGAGGQ---GGAGGAGSDGGALGGTGGTGGTGGAGGAGGR
Rv3508|M.tuberculosis_H37Rv         DGGWLAPGGAGGAGGQ---GGAGGAGSDGGALGGTGGTGGTGGAGGAGGR
MUL_4367|M.ulcerans_Agy99           SGGWLWG----NAGQT---AGAG-----------VGGAGGAGGAGDAGDQ
MMAR_2100|M.marinum_M               NARLLGTGGAGGDGGAGLAGAAGISGIAAGEAGTGGGIGGDGGVGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------VGATGAVGAPGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------AGATGAVGAPGVAGAT
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------------GTGGTGGIGGTGGG
TH_3810|M.thermoresistible__bu      ------------------------------------RTG-----------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------IASGQGSTAVNGDVRDS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------LLLVGSGVDVAPLKQVLQ
                                                                                      

Mb3538|M.bovis_AF2122/97            GALLLGAGGQGGLG-GAGGQGGTGGAGGDG---VLGGVGGTGGKGGVGGV
Rv3508|M.tuberculosis_H37Rv         GALLLGAGGQGGLG-GAGGQGGTGGAGGDG---VLGGVGGTGGKGGVGGV
MUL_4367|M.ulcerans_Agy99           GVSGVAPGEAGAVG-FAGGAGGAGGAGGNG---VGGGVNGAGGAGGAGGV
MMAR_2100|M.marinum_M               GGWLFGNGGAGGIG-GAGGAGGAGGFGASGDLVINQGSGADGGSGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          GATGVTSGVVGGNGEDAVGYGATGAAGAAG---------AAGAAGAAGAV
Mvan_1264|M.vanbaalenii_PYR-1       GATGVTSNVTGGNGADAVGYGATGAAGAAG---------AAGAAGKAGAV
MSMEG_0868|M.smegmatis_MC2_155      LFGLLGHSGSTGAA-GAAGNGGDGGNGGFGY-VLIAGPNVTVGSETRGGT
TH_3810|M.thermoresistible__bu      LFSKLSR-------------GGDGGDGGLG--------------------
MAB_4284c|M.abscessus_ATCC_199      NIINADHGSNVGVDQSQTRVGGDYTN------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TTTFLDVSVAEEPETALARGAALAAANAP---------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAG---------------
Rv3508|M.tuberculosis_H37Rv         AGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGL
MUL_4367|M.ulcerans_Agy99           GGGGGAG--------------ASGVG------------------------
MMAR_2100|M.marinum_M               GGAGGNGGAGGWLFSAHGAGGVGGAGGTGGTPGDGG--------------
Mflv_5091|M.gilvum_PYR-GCK          GSAGAAG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GSAGTAG-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGAGGTG-------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------------------------------GMGGSGADN
Rv3508|M.tuberculosis_H37Rv         TGGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADN
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               -------------------------------------------GGAHGSM
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQG
Rv3508|M.tuberculosis_H37Rv         ASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQG
MUL_4367|M.ulcerans_Agy99           ---AGVAGGDGGTGGAGGAAGVGGAAGTGGTG------GAAGVAGTGGDG
MMAR_2100|M.marinum_M               AVNPGAGFGTGGNGGNGGDPGAGGAGGTGGSGAGGSRAATGATGSTPSSG
Mflv_5091|M.gilvum_PYR-GCK          ------EAGETGTWGNAGLPGKAGDAG--------------GAGAVGAAG
Mvan_1264|M.vanbaalenii_PYR-1       ------SAGAPGVWGNAGLPGAAGAAG--------------GAGAIGTAG
MSMEG_0868|M.smegmatis_MC2_155      ----GQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNG
TH_3810|M.thermoresistible__bu      --------------GNGGHGGGTGIISLLS---------LAGNGGNGGNG
MAB_4284c|M.abscessus_ATCC_199      -------------VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRST
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDEL
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGAGSAGTDATATGATGGTGFSGGAG---GAGGAGGN--TGVGGTNGS
Rv3508|M.tuberculosis_H37Rv         GAGGAGSAGTDATATGATGGTGFSGGAG---GAGGAGGN--TGVGGTNGS
MUL_4367|M.ulcerans_Agy99           GDGGAGGAGSDASLAGQAG---FAGGSG---GAGGVGGS--AGAGGVNGS
MMAR_2100|M.marinum_M               GNGGAGGAGADSITTGGAGAAGGTGGDGGLVGDGGAGGDGGAGLGGAPGT
Mflv_5091|M.gilvum_PYR-GCK          AAGTVGTAG----ATGGTG----TGANG---GAGGVGGV-----------
Mvan_1264|M.vanbaalenii_PYR-1       VAGAAGTAG----ATGGTG----VGGNG---GAGQAGGI-----------
MSMEG_0868|M.smegmatis_MC2_155      STTAAGGNGGTGGTGRVIAEGTGSTAEG--TATGGDGGHS----------
TH_3810|M.thermoresistible__bu      YRTTDNN-----------------------ALDGGHGGN-----------
MAB_4284c|M.abscessus_ATCC_199      NIGSGNTTNTEIGSHNQANIGTSTSAGG----SAAVGGN-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSG-----------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----GGQ-GGTGGAGGAGGAGGVGADNPTGIGGAGGTGG----------
Rv3508|M.tuberculosis_H37Rv         -----GGQ-GGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQ
MUL_4367|M.ulcerans_Agy99           -----GGD-GGAGAAGGAGGASAT-------VAGSGGVGG----------
MMAR_2100|M.marinum_M               SVIFPGGQPGSSGGDGGAGGAGGAGGDG-GLVAGNGGVGG----------
Mflv_5091|M.gilvum_PYR-GCK          ---------GGTGAAGAAGGAGGLG--------ETGTTGG----------
Mvan_1264|M.vanbaalenii_PYR-1       ---------GGTGAAGAAGQAGTAG--------ETGVTGG----------
MSMEG_0868|M.smegmatis_MC2_155      -------TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGG----------
TH_3810|M.thermoresistible__bu      ------------GGNVGFFSLFNLG--------GAGGWGG----------
MAB_4284c|M.abscessus_ATCC_199      -----------AGLAGNAGLAGNAG------LAGNAGLAG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------LAVVGISAVLALEIALAIGIRTTGTVALQP--------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------------------AGGTGGTGGA
Rv3508|M.tuberculosis_H37Rv         GGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGA
MUL_4367|M.ulcerans_Agy99           -------------------------------------------DGGAGGA
MMAR_2100|M.marinum_M               ----------------------------------------AGGIGGVGGT
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------AGGVGGQ
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------VGGIGGQ
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------DGIDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------SGVDG-
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGAGGAGGAVGTGGTGGVVGDVGNAGIGGTGGKGGAGGTG----------
Rv3508|M.tuberculosis_H37Rv         AGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGS
MUL_4367|M.ulcerans_Agy99           AGGG-----------------VGAASLGGDGGHAGAGGAG----------
MMAR_2100|M.marinum_M               GGDGSVG--------------VDAAGAGQDGGVGGAGGAGGAGG------
Mflv_5091|M.gilvum_PYR-GCK          GTAG------------------------GTGGVGGIGGAG----------
Mvan_1264|M.vanbaalenii_PYR-1       GTEG------------------------GTGGVGGVGGVG----------
MSMEG_0868|M.smegmatis_MC2_155      TGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSW------
TH_3810|M.thermoresistible__bu      --------------------------------VDVVGGN-----------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------NAGLAGNAG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -------FAGGAGGAGGQGGSSGAG----GTNGSGGAGGTGGQGG-----
Rv3508|M.tuberculosis_H37Rv         SATGGAGFAGGAGGEGGAGGNSGVG----GTNGSGGAGGAGGKGG-----
MUL_4367|M.ulcerans_Agy99           -------------GEGLSGGFN--------------TGAAGGIGG-----
MMAR_2100|M.marinum_M               --------AGGAGGEGGAGGHALAAGYADGSQGAGGAGGAGGIGG-----
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------STGAVGGVGG-----
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------ATGGAGGVGG-----
MSMEG_0868|M.smegmatis_MC2_155      ----------VQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVM
TH_3810|M.thermoresistible__bu      -----------------------------------PDGGTPG--------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------LAGNAGLAG-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------TPNQHLIVP-----
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVG
Rv3508|M.tuberculosis_H37Rv         TGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATG
MUL_4367|M.ulcerans_Agy99           AGGAGGTGGD-------SGGVGGVNGDGGAGGGGGRGGDGGS-----STS
MMAR_2100|M.marinum_M               DGAAGGKGAEGAAAAG-AGADGNDGGNGGRGGAGGRGGDGGVG----GAG
Mflv_5091|M.gilvum_PYR-GCK          KGIQGGQGLQ--------GGKGGDGGAGGKGGDADSMGSAGAT-------
Mvan_1264|M.vanbaalenii_PYR-1       KGIQGGQGLQ--------GGQGGDGGTGGTGGDATSMGEAGAT-------
MSMEG_0868|M.smegmatis_MC2_155      AAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATS
TH_3810|M.thermoresistible__bu      --------------------------------------AHG---------
MAB_4284c|M.abscessus_ATCC_199      -----------------------NAGLAGNAGLAGNAGLAGN--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------TEQAPAPPPVQASAPQ-------
                                                                                      

Mb3538|M.bovis_AF2122/97            NAGIG-------------------------------------------GT
Rv3508|M.tuberculosis_H37Rv         SAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGA
MUL_4367|M.ulcerans_Agy99           TSGVG-------------------------------------------GA
MMAR_2100|M.marinum_M               PEGQT-------------------------------------------GM
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GH----------------------------------------------GG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAG-----------------
Rv3508|M.tuberculosis_H37Rv         GGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKA
MUL_4367|M.ulcerans_Agy99           GGAGGNGGNAGFGVSAGG----TGGSAGDGGAG-----------------
MMAR_2100|M.marinum_M               QGVGGAGGDGGLGGQAGNGSDGADAIVGGGKGG-----------------
Mflv_5091|M.gilvum_PYR-GCK          GGKGGNGGNGGRGGLFGK-----GGNAGNGADG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       GGKGGNGGNGGRGSLFGR-----GGNAGNGGNG-----------------
MSMEG_0868|M.smegmatis_MC2_155      AAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKA-----------------
TH_3810|M.thermoresistible__bu      ---------------ESHTP----GVYTDRQ-------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAGN-----AGLAGNAGLA-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPP-----------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GEGGAGGNSGVGGTNGSGGAG---------GAGGKGGTGGAGGSGADNPT
Rv3508|M.tuberculosis_H37Rv         GDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSIN
MUL_4367|M.ulcerans_Agy99           --GGAGGVDGVGGASGNGGAA---------GAGGAGGSGIGAG-------
MMAR_2100|M.marinum_M               -DGGDGGDPGLGGAGGQGGAG--------STAGMEGLTAGDDGP------
Mflv_5091|M.gilvum_PYR-GCK          ---GTGGAGGAGGTGGTGGAG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGNGGNGGTGGTGGNG-----------------------------
MSMEG_0868|M.smegmatis_MC2_155      -AGGNGGDGGFNGTGGATG-------------------------------
TH_3810|M.thermoresistible__bu      ------GEDGEDGTGTGIG-------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------GNAGLAGNAGLAGNA-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----LPEAPPIPAAPPVVPVP-----------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGFAGGAGGTGGAAGAGGAG--------------GATGTGGTGGVVGAT
Rv3508|M.tuberculosis_H37Rv         ANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAA
MUL_4367|M.ulcerans_Agy99           IDGGAGGAGGTGGAAGFPGGG--------------GTTGAWGTGGAGGAG
MMAR_2100|M.marinum_M               GHGGDGGAGGDGAAAVTTGSAG----------------GDGGAGGDGGLV
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGIGGAGSTGGTG-----------------GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGIGGAGSTGGTG-----------------GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GRGGDGAGASVWKANGQHSTGQT------------DTGGNGGRGGDGGTF
TH_3810|M.thermoresistible__bu      GRGGNGG-----SSSGTHPMAE----------------------------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAGLAGNAGLAG-----------------NAAVAGNAAVA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VVVPPVPVPVPVRIPVPDPVSP------------------PQLLAPPRLS
                                                                                      

Mb3538|M.bovis_AF2122/97            GSAGIGGAGGRGGDGGDGASGLG-LGLSGFDGGQGGQGGDGGSAGAGGIN
Rv3508|M.tuberculosis_H37Rv         GKAGGGGNGGRGGDGGDGASGLG-LGLSGFDGGQGGQGGAGGSAGAGGIN
MUL_4367|M.ulcerans_Agy99           GAGGAGDHGGVGVNPGD-------SGTAGWAGGAGGAGGAGGSAAFNGVN
MMAR_2100|M.marinum_M               GDGGVGGNGGTGADGSPGITFISPGGLSGTDGGAGSIGGTGGAGGAGGLH
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGTG--------------------GTGGKGGTGGTGGAGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGTG--------------------GTGGKGGTGGTGGDGGTG
MSMEG_0868|M.smegmatis_MC2_155      VNAGANGNGGAGGAGGVSEGEGG----TGGHGGDGGRGGDGALGGNGGTG
TH_3810|M.thermoresistible__bu      -------------------------------DGEHVKALDGRPGLDG---
MAB_4284c|M.abscessus_ATCC_199      GNAAVAGNAAVG--------------------GVLNTGVSGAIGGSSHVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPQPVQPPVRVP-------------------QPPSPPQVGGTVPQSPPQH
                                                                                      

Mb3538|M.bovis_AF2122/97            ----GAGGAGGDGGDGGDGATG-----AAGLGDNGGVGGDGGAGGAAGNG
Rv3508|M.tuberculosis_H37Rv         ----GAGGAGGNGGDGGDGATG-----AAGLGDNGGVGGDGGAGGAAGNG
MUL_4367|M.ulcerans_Agy99           ----GAGGAGGNGGAGGGGGAG-----ASGIG-AGVAGGDGGTGGTGG--
MMAR_2100|M.marinum_M               AGDGGAGGIGGTGGDGGHGGSGSAGADATIAGAAGQTGGDGGDGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          ----GDGGTGGTGGTGGTGGTG----------------GTGGTGGAG---
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGGTGGTGGTGGTGGTG----------------GTGGTGGAG---
MSMEG_0868|M.smegmatis_MC2_155      GVGLGNGGKGGNGGNGGNGGTY----------VDPSHTGAGGNGGNGGAG
TH_3810|M.thermoresistible__bu      ----GNGSHGGNGGHGGRGG----------------FLGIGGSGGWG---
MAB_4284c|M.abscessus_ATCC_199      G--AINESLGGSGSVGGSTAVG-----------------GGAHTGVG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QTPPGEGTPPKPDGPGNYGGGHVP------------TPGAGGSGGSG---
                                                                                      

Mb3538|M.bovis_AF2122/97            GNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQG
Rv3508|M.tuberculosis_H37Rv         GNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQG
MUL_4367|M.ulcerans_Agy99           ---------AAGTGGAAGTGGTGGAAGAAGS-------------------
MMAR_2100|M.marinum_M               GAGGAG-GLAQATGYLDGSHGSGGSGGAGGQAGNAGDGGDG---------
Mflv_5091|M.gilvum_PYR-GCK          ----------DGTGGTGGTGGTGGQGGQGGQ-------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------DGLGGTGGTGGTGGFGGQGGQ-------------------
MSMEG_0868|M.smegmatis_MC2_155      RI-----RVNNGTATGTATGGNGGNGGNG---------------------
TH_3810|M.thermoresistible__bu      --------------------GHGGNGGDT---------------------
MAB_4284c|M.abscessus_ATCC_199      -------------GGVSTGVGVGSHVGGGIS-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------GGHVPTPGAGGSGGSGGG-------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GLGGASTTSINANGGAGGNGGTGGKGGAGGAG-TLGVGGSGGTGGDGGDA
Rv3508|M.tuberculosis_H37Rv         GLGGASTTSINANGGAGGNGGTGGKGGAGGAG-TLGVGGSGGTGGDGGDA
MUL_4367|M.ulcerans_Agy99           ----------------AGDGGAGGAGGAGDDG-SAGVVS-----GDPGTA
MMAR_2100|M.marinum_M               ----------------ADATVAGGKGGAGGNGGDAGVGGSGGLGGDSGNG
Mflv_5091|M.gilvum_PYR-GCK          ----------------GGTGGTGGQGGLGGGG------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------GGTGGTGGQGGLGGVG------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------DADGHRGGKGGDGGEA------------------
TH_3810|M.thermoresistible__bu      ----------------DADGGNGGDGGNGG--------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------ESLGGSGSVGGSTAVG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------HVPTPGTGGPGGTGGSG------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGGGGFGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGG
Rv3508|M.tuberculosis_H37Rv         GSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGG
MUL_4367|M.ulcerans_Agy99           GKAGG-----------AGGAGGVGGN-------------GVAGGVNGSGG
MMAR_2100|M.marinum_M               THAANG---ASAGAYGTGGNGGAGGDGAD---------ATAAGQAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ---------------GTGGQGGTGGT----------------GGQGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------GTGGTGGTGGT----------------GGQGGTGG
MSMEG_0868|M.smegmatis_MC2_155      -LIRATVIGSNASGTATGGDGGNGGT---------------LGATNGTGG
TH_3810|M.thermoresistible__bu      ----------------SAGRGGTGGL---------------RGVF-----
MAB_4284c|M.abscessus_ATCC_199      ----------------GGAHTGVGGG------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------GGHVPTPGA------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGP--DGGDGGQGGIGGD
Rv3508|M.tuberculosis_H37Rv         AGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGP--DGGDGGQGGIGGD
MUL_4367|M.ulcerans_Agy99           AG---------GAGGAGGTGGAGASGVPASVDGG---DGGAGGAGGAAGT
MMAR_2100|M.marinum_M               AGGDGGVVGDGGVGGNGGDGKAGVDGTSAVTFGASGADGGDGGAGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          TG---------GTGGTGGTGGAGG-------------DGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1       TG---------GTGGTGGTGGAGG-------------DGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155      AATIVAYNVVQANPQASGTATDGH--------------GGSGINGGHGGN
TH_3810|M.thermoresistible__bu      -----------------------------------------GINGGNGR-
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------VSTGVGVGSHVGGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------GTPGGSGGG
                                                                                      

Mb3538|M.bovis_AF2122/97            GGNAGFGAGVPGDGGIGG----------TGGAGGAGGAGGAGDAGADGDP
Rv3508|M.tuberculosis_H37Rv         GGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDP
MUL_4367|M.ulcerans_Agy99           GG--------------------------SGGSAGNTGAGGAG--------
MMAR_2100|M.marinum_M               GGDGGAVAGDGGRGGAGG----------DGAMGGNGGNGFDGLHG--TTP
Mflv_5091|M.gilvum_PYR-GCK          GG--------------------------TGGQGGLGGPGGST--------
Mvan_1264|M.vanbaalenii_PYR-1       GG--------------------------TGGQGGQGGPGGST--------
MSMEG_0868|M.smegmatis_MC2_155      GGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANP
TH_3810|M.thermoresistible__bu      -----------------------------AGLGGRGXX------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------ISESLGGSGSVGGST--------
MLBr_01183|M.leprae_Br4923          -----------------------------MPLFLNAEPQALT--------
MAV_4827|M.avium_104                ----------------------------HLPFPGAGSTPG----------
                                                                                      

Mb3538|M.bovis_AF2122/97            SIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD
Rv3508|M.tuberculosis_H37Rv         SIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD
MUL_4367|M.ulcerans_Agy99           -------GAGGAGGSAASTGVN---------GDGGAGGAGGVGGLGGDSA
MMAR_2100|M.marinum_M               GANGQYGGDGGEGGRGGVGGAGGAG-GAAAAGQAGSQGDGGNGGDGGDGG
Mflv_5091|M.gilvum_PYR-GCK          ------GGAGGAGGQAGTAGKGG--------LFGGSGSAGKAGATGAAGA
Mvan_1264|M.vanbaalenii_PYR-1       ------GGAGGAGGQAGVAGKGG--------LFGGSGSAGTAGVTGASGA
MSMEG_0868|M.smegmatis_MC2_155      GSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGK
TH_3810|M.thermoresistible__bu      ----------XXGGGVGAAVRSGNG----VFSGGG--------GTPSAGF
MAB_4284c|M.abscessus_ATCC_199      --------AVGGGAHTGVGGGVNTG----------------VGVGSHVGG
MLBr_01183|M.leprae_Br4923          ---------AAANTLEGLSAAT---------------------VASNAAA
MAV_4827|M.avium_104                ---------GSGGGHLPTPGAGTPG-----------------GGLGGFGG
                                                .                                   . 

Mb3538|M.bovis_AF2122/97            GFIGGSGGTGGTGGDAGAGGLANTGGTAGNAGIGGAGGRGGDGGAGD-SG
Rv3508|M.tuberculosis_H37Rv         GFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGD-SG
MUL_4367|M.ulcerans_Agy99           ATAGG-GGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGS-DG
MMAR_2100|M.marinum_M               --TPGNGGSGADGANSAIGVSAGDGGYGGAGGNAGAGGLGGEGGAGSTSG
Mflv_5091|M.gilvum_PYR-GCK          S--GGKGAQGATGAQGATGAQGATGATGAAGKAGATGAAGAAGAAGS-AG
Mvan_1264|M.vanbaalenii_PYR-1       S--GGKGAQGATGAQGATGAQGATGATGASGAQGSAGSAGSAGVAGS-AG
MSMEG_0868|M.smegmatis_MC2_155      GGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAG
TH_3810|M.thermoresistible__bu      GVPTT---IQFPAGSCTSRAVSREGIMPSSRAASARAGAACASSTSRSRR
MAB_4284c|M.abscessus_ATCC_199      GISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTS
MLBr_01183|M.leprae_Br4923          AQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS---
MAV_4827|M.avium_104                GHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------
                                                            .        ..  .            

Mb3538|M.bovis_AF2122/97            ALSQDGNGFAGGQGGQGGAGGNA------GAGGINGAGGTGGTGGAGGDG
Rv3508|M.tuberculosis_H37Rv         ALSQDGNGFAGGQGGQGGVGGNA------GAGGINGAGGTGGTGGAGGDG
MUL_4367|M.ulcerans_Agy99           IIPSNG-----GLGGNGGNGGNG------GQAFGDGVGGAGGIGGKGGNA
MMAR_2100|M.marinum_M               ASGLDGSQAAGGDGGNGGFGGTGGLFEAAGSGGAGGVGGDGSQGGDGGDG
Mflv_5091|M.gilvum_PYR-GCK          TTGAQGS--AGTNGANGANGSQG------AAGKAGATGTTGATGAAGEDG
Mvan_1264|M.vanbaalenii_PYR-1       TTGAQGS--AGTNGANGANGSQG------AAGKAGATGTTGATGAAGDAG
MSMEG_0868|M.smegmatis_MC2_155      GFSNIAAIHGAITDSTAISGHGG-----AGNGGNGGKGADGWVQAYDPAG
TH_3810|M.thermoresistible__bu      SFCCSRA-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AINESMNSSINASHSSSMNESFG------SSMGSHGAAGTGFEAQGHAQG
MLBr_01183|M.leprae_Br4923          LLTSSSAYAGTETANHDSL-------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            APATLIGGPDGGDGGQGG------------GAGFGSGVAG----------
Rv3508|M.tuberculosis_H37Rv         QNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGA
MUL_4367|M.ulcerans_Agy99           AIGTIVIN--GGVGGAGG--------------------------------
MMAR_2100|M.marinum_M               GAGGSSPGATGGWGGQGG--------------------------------
Mflv_5091|M.gilvum_PYR-GCK          DAGSGGSGINGGAGGAGG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       DPGSEAVDINGGAGGAGG--------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PVGSKIANSSAVAGNGGD--------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      HASETAHTTLPGAEHH----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AAGAGGNGGKG-----GDGGTGGTG-------------------------
Rv3508|M.tuberculosis_H37Rv         AGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               -----------------LGGVGTAG-------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------GTNFAGGQGG------------------AGGRGG
Rv3508|M.tuberculosis_H37Rv         RGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------SGGLGG
MMAR_2100|M.marinum_M               --------------------------------------------VGGHGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------------GGVNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGNGANG------------------------------------------
Rv3508|M.tuberculosis_H37Rv         AGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIG
MUL_4367|M.ulcerans_Agy99           ATEDGVGG------------------------------------------
MMAR_2100|M.marinum_M               DGGDAGDS------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGG-----------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2100|M.marinum_M               ----------------------------------------------GSSA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            VGDNAAGGDGGNGGAGGLGGG-GGTGGTNGNGGLGGGGGNGGAGGAGGTP
Rv3508|M.tuberculosis_H37Rv         GGNGGAGGAGGNGGAGGLGGG-GGTGGTNGNGGLGGGGGNGGAGGAGGTP
MUL_4367|M.ulcerans_Agy99           --VGCAGGAGGNGGRG------------DMLFTVGGSGGTGGDGGGGGSA
MMAR_2100|M.marinum_M               FGVGSPGGGGGQGGFGVAGGGDGGDGGNGGAGGFGQNGGPGGRGGGGG-H
Mflv_5091|M.gilvum_PYR-GCK          -----AGGEGGEGGDG-------------GKGGAGAEGGAGGGGGAGG--
Mvan_1264|M.vanbaalenii_PYR-1       -----AGGEGGEGGAG-------------GAGGDGSEGGAGGSGGAGG--
MSMEG_0868|M.smegmatis_MC2_155      ----ASGGDGGNGGNTSVWKS--------GGQTADGEHNTGGNGGNGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            TGSGTEGTGGDGGDAGAGGNGGSA-TGVGNGGNGGDGGNGGDGGN-GAPG
Rv3508|M.tuberculosis_H37Rv         TGSGTEGTGGDGGDAGAGGNGGSA-TGVGNGGNGGDGGNGGDGGN-GAPG
MUL_4367|M.ulcerans_Agy99           SGSGTGGSGGTGGVGGIGGDGK-------LGGFGGDGGDGGDGGF-GVIG
MMAR_2100|M.marinum_M               SLVGPGGDGGLGGTGGNGGNGSQPPFGSTPAGSGGDGGNGGAGGSSGFVS
Mflv_5091|M.gilvum_PYR-GCK          --SGAGGAGGAGGSGGSG-------------GSGGSGGSGGAAGD-----
Mvan_1264|M.vanbaalenii_PYR-1       --SGTGGAGGAGGSGGSG-------------GSGGAGGSGGAAGD-----
MSMEG_0868|M.smegmatis_MC2_155      SEPGPGGNGA-GGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGT-----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS
Rv3508|M.tuberculosis_H37Rv         GFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS
MUL_4367|M.ulcerans_Agy99           GQGGGGGFGGLGGTGAGG-APSDKGINGEPGNPG-
MMAR_2100|M.marinum_M               GQSGTDGQDGGDPSGQFGGTGGAGGSGGAGAGT--
Mflv_5091|M.gilvum_PYR-GCK          ---------------------SDD-----------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------SD------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------PGTAGTTGANNP---
TH_3810|M.thermoresistible__bu      -----------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------
MLBr_01183|M.leprae_Br4923          -----------------------------------
MAV_4827|M.avium_104                -----------------------------------