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MSFVSVTPEMVVAAASDLSGINSAIAQANSVAAAATTTVLPAAADEVSAAIAALFGTHAQQYQAISAELA AFHDRFVQSLNTGAGSYLRAEAANAEQGLLGLVNAPTQALFGRPLIGDGANGAPGSGQAGGAGGLLYGNG GAGGSGGVGQAGGAGGAAGLIGSGGAGGAGGAGGTGGAGGAGGWLYGNGGAGGVGGAGAVGGAGGNTWLW GNGGAGGSGGVGSGSGGAGGSGGWLYGNGGAGGTGGVADGVGEGGGHGGAGGNARLLGTGGAGGDGGAGL AGAAGISGIAAGEAGTGGGIGGDGGVGGDGGAGGWLFGNGGAGGIGGAGGAGGAGGFGASGDLVINQGSG ADGGSGGAGGAGGAGGNGGAGGWLFSAHGAGGVGGAGGTGGTPGDGGGGAHGSMAVNPGAGFGTGGNGGN GGDPGAGGAGGTGGSGAGGSRAATGATGSTPSSGGNGGAGGAGADSITTGGAGAAGGTGGDGGLVGDGGA GGDGGAGLGGAPGTSVIFPGGQPGSSGGDGGAGGAGGAGGDGGLVAGNGGVGGAGGIGGVGGTGGDGSVG VDAAGAGQDGGVGGAGGAGGAGGAGGAGGEGGAGGHALAAGYADGSQGAGGAGGAGGIGGDGAAGGKGAE GAAAAGAGADGNDGGNGGRGGAGGRGGDGGVGGAGPEGQTGMQGVGGAGGDGGLGGQAGNGSDGADAIVG GGKGGDGGDGGDPGLGGAGGQGGAGSTAGMEGLTAGDDGPGHGGDGGAGGDGAAAVTTGSAGGDGGAGGD GGLVGDGGVGGNGGTGADGSPGITFISPGGLSGTDGGAGSIGGTGGAGGAGGLHAGDGGAGGIGGTGGDG GHGGSGSAGADATIAGAAGQTGGDGGDGGAGGAGGAGGAGGLAQATGYLDGSHGSGGSGGAGGQAGNAGD GGDGADATVAGGKGGAGGNGGDAGVGGSGGLGGDSGNGTHAANGASAGAYGTGGNGGAGGDGADATAAGQ AGGAGGAGGDGGVVGDGGVGGNGGDGKAGVDGTSAVTFGASGADGGDGGAGGAGGAGGDGGAVAGDGGRG GAGGDGAMGGNGGNGFDGLHGTTPGANGQYGGDGGEGGRGGVGGAGGAGGAAAAGQAGSQGDGGNGGDGG DGGTPGNGGSGADGANSAIGVSAGDGGYGGAGGNAGAGGLGGEGGAGSTSGASGLDGSQAAGGDGGNGGF GGTGGLFEAAGSGGAGGVGGDGSQGGDGGDGGAGGSSPGATGGWGGQGGLGGVGTAGVGGHGGDGGDAGD SGSSAFGVGSPGGGGGQGGFGVAGGGDGGDGGNGGAGGFGQNGGPGGRGGGGGHSLVGPGGDGGLGGTGG NGGNGSQPPFGSTPAGSGGDGGNGGAGGSSGFVSGQSGTDGQDGGDPSGQFGGTGGAGGSGGAGAGT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2100 | - | - | 100% (1397) | PE-PGRS family protein |
M. marinum M | MMAR_2656 | - | 0.0 | 55.72% (1468) | PE-PGRS family protein, PE_PGRS50 |
M. marinum M | MMAR_1442 | - | 0.0 | 55.66% (1450) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | 0.0 | 53.28% (1492) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-179 | 46.22% (846) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 50.27% (1637) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 5e-14 | 39.13% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-54 | 36.05% (441) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 3e-25 | 42.11% (171) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-165 | 40.02% (1092) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 9e-45 | 43.94% (289) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 49.21% (1136) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-177 | 46.86% (828) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQV Rv3508|M.tuberculosis_H37Rv -----------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQV MUL_4367|M.ulcerans_Agy99 -----------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGV MMAR_2100|M.marinum_M -----------MSFVSVTPEMVVAAASDLSGINSAIAQANSVAAAATTTV Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------MMFLAPPGGPGPISAAIQL MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGA Mb3538|M.bovis_AF2122/97 LAAGADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS Rv3508|M.tuberculosis_H37Rv LAAGADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS MUL_4367|M.ulcerans_Agy99 LPAAGDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ MMAR_2100|M.marinum_M LPAAADEVSAAIAALFGTHAQQYQAISAELAAFHDRFVQSLNTGAGSYLR Mflv_5091|M.gilvum_PYR-GCK ------------MVTFGGGA------TPTPTSLGAAAVDLSGTSCG---- Mvan_1264|M.vanbaalenii_PYR-1 TSTGSEATEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG---- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 QVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPD---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 DDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR--- Mb3538|M.bovis_AF2122/97 AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT Rv3508|M.tuberculosis_H37Rv AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT MUL_4367|M.ulcerans_Agy99 AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA MMAR_2100|M.marinum_M AEAAN---------------AEQGLLGLVNAPTQALFGRPLIGDGANGAP Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQD--- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------GPSILS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------DALAARRIDNVM Mb3538|M.bovis_AF2122/97 TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG Rv3508|M.tuberculosis_H37Rv TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-- MMAR_2100|M.marinum_M GSGQAGGAGGLLYGNGGAGG-SGGVGQAGGAGGAAGLIGSGGAGGAGGAG Mflv_5091|M.gilvum_PYR-GCK ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG-- Mvan_1264|M.vanbaalenii_PYR-1 ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG-- MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRG------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY Mb3538|M.bovis_AF2122/97 GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGG---LIWGGGGAGG Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGG---LIWGGGGAGG MUL_4367|M.ulcerans_Agy99 ---------------VGAAG----MTGGSGGAGGGGG---WLWGAGGSGG MMAR_2100|M.marinum_M G-TGGAGGAGGWLYGNGGAG----GVGGAGAVGGAGGN-TWLWGNGGAGG Mflv_5091|M.gilvum_PYR-GCK ------------------------LGGGNGGNGGNAGA-FALFGNGGNGG Mvan_1264|M.vanbaalenii_PYR-1 ------------------------LGSGDGGNGGDAGL-FSLFGRGGNGG MSMEG_0868|M.smegmatis_MC2_155 -----------LDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGG TH_3810|M.thermoresistible__bu -------------------------------------------VD----G MAB_4284c|M.abscessus_ATCC_199 -----------------------PLLDLSFGDLQFGNRDTTAIGDGAVAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------KQQIRAESYGDAAGQLSAMVAGLEKL Mb3538|M.bovis_AF2122/97 VGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGG Rv3508|M.tuberculosis_H37Rv VGGAGGGTGGAGGRAELLFGAGGAGGAG---TDGGPGATGGTGGHGGVGG MUL_4367|M.ulcerans_Agy99 AAGAGG-----------------------------------------SGG MMAR_2100|M.marinum_M SGGVGSGSGGAGGSGGWLYGNGGAGGTG-----GVADGVGEGGGHGGAGG Mflv_5091|M.gilvum_PYR-GCK NGGVGV-------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 NGGVGI-------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGGTGG-------------------------------------------- TH_3810|M.thermoresistible__bu DGGSGG-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSNSGP------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ESLPGG-------------------------------------------- Mb3538|M.bovis_AF2122/97 DGGWLAPGGAGGAGGQ---GGAGGAGSDGGALGGTGGTGGTGGAGGAGGR Rv3508|M.tuberculosis_H37Rv DGGWLAPGGAGGAGGQ---GGAGGAGSDGGALGGTGGTGGTGGAGGAGGR MUL_4367|M.ulcerans_Agy99 SGGWLWG----NAGQT---AGAG-----------VGGAGGAGGAGDAGDQ MMAR_2100|M.marinum_M NARLLGTGGAGGDGGAGLAGAAGISGIAAGEAGTGGGIGGDGGVGGDGGA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------VGATGAVGAPGVAGAT Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------AGATGAVGAPGVAGAT MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------GTGGTGGIGGTGGG TH_3810|M.thermoresistible__bu ------------------------------------RTG----------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------IASGQGSTAVNGDVRDS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------LLLVGSGVDVAPLKQVLQ Mb3538|M.bovis_AF2122/97 GALLLGAGGQGGLG-GAGGQGGTGGAGGDG---VLGGVGGTGGKGGVGGV Rv3508|M.tuberculosis_H37Rv GALLLGAGGQGGLG-GAGGQGGTGGAGGDG---VLGGVGGTGGKGGVGGV MUL_4367|M.ulcerans_Agy99 GVSGVAPGEAGAVG-FAGGAGGAGGAGGNG---VGGGVNGAGGAGGAGGV MMAR_2100|M.marinum_M GGWLFGNGGAGGIG-GAGGAGGAGGFGASGDLVINQGSGADGGSGGAGGA Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAVGYGATGAAGAAG---------AAGAAGAAGAV Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAVGYGATGAAGAAG---------AAGAAGKAGAV MSMEG_0868|M.smegmatis_MC2_155 LFGLLGHSGSTGAA-GAAGNGGDGGNGGFGY-VLIAGPNVTVGSETRGGT TH_3810|M.thermoresistible__bu LFSKLSR-------------GGDGGDGGLG-------------------- MAB_4284c|M.abscessus_ATCC_199 NIINADHGSNVGVDQSQTRVGGDYTN------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TTTFLDVSVAEEPETALARGAALAAANAP--------------------- Mb3538|M.bovis_AF2122/97 AGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAG--------------- Rv3508|M.tuberculosis_H37Rv AGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGL MUL_4367|M.ulcerans_Agy99 GGGGGAG--------------ASGVG------------------------ MMAR_2100|M.marinum_M GGAGGNGGAGGWLFSAHGAGGVGGAGGTGGTPGDGG-------------- Mflv_5091|M.gilvum_PYR-GCK GSAGAAG------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAG------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGAGGTG------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------------------------------GMGGSGADN Rv3508|M.tuberculosis_H37Rv TGGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADN MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M -------------------------------------------GGAHGSM Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQG Rv3508|M.tuberculosis_H37Rv ASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQG MUL_4367|M.ulcerans_Agy99 ---AGVAGGDGGTGGAGGAAGVGGAAGTGGTG------GAAGVAGTGGDG MMAR_2100|M.marinum_M AVNPGAGFGTGGNGGNGGDPGAGGAGGTGGSGAGGSRAATGATGSTPSSG Mflv_5091|M.gilvum_PYR-GCK ------EAGETGTWGNAGLPGKAGDAG--------------GAGAVGAAG Mvan_1264|M.vanbaalenii_PYR-1 ------SAGAPGVWGNAGLPGAAGAAG--------------GAGAIGTAG MSMEG_0868|M.smegmatis_MC2_155 ----GQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNG TH_3810|M.thermoresistible__bu --------------GNGGHGGGTGIISLLS---------LAGNGGNGGNG MAB_4284c|M.abscessus_ATCC_199 -------------VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRST MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDEL Mb3538|M.bovis_AF2122/97 GAGGAGSAGTDATATGATGGTGFSGGAG---GAGGAGGN--TGVGGTNGS Rv3508|M.tuberculosis_H37Rv GAGGAGSAGTDATATGATGGTGFSGGAG---GAGGAGGN--TGVGGTNGS MUL_4367|M.ulcerans_Agy99 GDGGAGGAGSDASLAGQAG---FAGGSG---GAGGVGGS--AGAGGVNGS MMAR_2100|M.marinum_M GNGGAGGAGADSITTGGAGAAGGTGGDGGLVGDGGAGGDGGAGLGGAPGT Mflv_5091|M.gilvum_PYR-GCK AAGTVGTAG----ATGGTG----TGANG---GAGGVGGV----------- Mvan_1264|M.vanbaalenii_PYR-1 VAGAAGTAG----ATGGTG----VGGNG---GAGQAGGI----------- MSMEG_0868|M.smegmatis_MC2_155 STTAAGGNGGTGGTGRVIAEGTGSTAEG--TATGGDGGHS---------- TH_3810|M.thermoresistible__bu YRTTDNN-----------------------ALDGGHGGN----------- MAB_4284c|M.abscessus_ATCC_199 NIGSGNTTNTEIGSHNQANIGTSTSAGG----SAAVGGN----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSG----------- Mb3538|M.bovis_AF2122/97 -----GGQ-GGTGGAGGAGGAGGVGADNPTGIGGAGGTGG---------- Rv3508|M.tuberculosis_H37Rv -----GGQ-GGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQ MUL_4367|M.ulcerans_Agy99 -----GGD-GGAGAAGGAGGASAT-------VAGSGGVGG---------- MMAR_2100|M.marinum_M SVIFPGGQPGSSGGDGGAGGAGGAGGDG-GLVAGNGGVGG---------- Mflv_5091|M.gilvum_PYR-GCK ---------GGTGAAGAAGGAGGLG--------ETGTTGG---------- Mvan_1264|M.vanbaalenii_PYR-1 ---------GGTGAAGAAGQAGTAG--------ETGVTGG---------- MSMEG_0868|M.smegmatis_MC2_155 -------TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGG---------- TH_3810|M.thermoresistible__bu ------------GGNVGFFSLFNLG--------GAGGWGG---------- MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAG------LAGNAGLAG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------LAVVGISAVLALEIALAIGIRTTGTVALQP-------- Mb3538|M.bovis_AF2122/97 ----------------------------------------AGGTGGTGGA Rv3508|M.tuberculosis_H37Rv GGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------DGGAGGA MMAR_2100|M.marinum_M ----------------------------------------AGGIGGVGGT Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------AGGVGGQ Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------VGGIGGQ MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------DGIDGG TH_3810|M.thermoresistible__bu --------------------------------------------SGVDG- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AGAGGAGGAVGTGGTGGVVGDVGNAGIGGTGGKGGAGGTG---------- Rv3508|M.tuberculosis_H37Rv AGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGS MUL_4367|M.ulcerans_Agy99 AGGG-----------------VGAASLGGDGGHAGAGGAG---------- MMAR_2100|M.marinum_M GGDGSVG--------------VDAAGAGQDGGVGGAGGAGGAGG------ Mflv_5091|M.gilvum_PYR-GCK GTAG------------------------GTGGVGGIGGAG---------- Mvan_1264|M.vanbaalenii_PYR-1 GTEG------------------------GTGGVGGVGGVG---------- MSMEG_0868|M.smegmatis_MC2_155 TGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSW------ TH_3810|M.thermoresistible__bu --------------------------------VDVVGGN----------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------NAGLAGNAG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------FAGGAGGAGGQGGSSGAG----GTNGSGGAGGTGGQGG----- Rv3508|M.tuberculosis_H37Rv SATGGAGFAGGAGGEGGAGGNSGVG----GTNGSGGAGGAGGKGG----- MUL_4367|M.ulcerans_Agy99 -------------GEGLSGGFN--------------TGAAGGIGG----- MMAR_2100|M.marinum_M --------AGGAGGEGGAGGHALAAGYADGSQGAGGAGGAGGIGG----- Mflv_5091|M.gilvum_PYR-GCK -----------------------------------STGAVGGVGG----- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------ATGGAGGVGG----- MSMEG_0868|M.smegmatis_MC2_155 ----------VQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVM TH_3810|M.thermoresistible__bu -----------------------------------PDGGTPG-------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LAGNAGLAG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------TPNQHLIVP----- Mb3538|M.bovis_AF2122/97 AGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVG Rv3508|M.tuberculosis_H37Rv TGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATG MUL_4367|M.ulcerans_Agy99 AGGAGGTGGD-------SGGVGGVNGDGGAGGGGGRGGDGGS-----STS MMAR_2100|M.marinum_M DGAAGGKGAEGAAAAG-AGADGNDGGNGGRGGAGGRGGDGGVG----GAG Mflv_5091|M.gilvum_PYR-GCK KGIQGGQGLQ--------GGKGGDGGAGGKGGDADSMGSAGAT------- Mvan_1264|M.vanbaalenii_PYR-1 KGIQGGQGLQ--------GGQGGDGGTGGTGGDATSMGEAGAT------- MSMEG_0868|M.smegmatis_MC2_155 AAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATS TH_3810|M.thermoresistible__bu --------------------------------------AHG--------- MAB_4284c|M.abscessus_ATCC_199 -----------------------NAGLAGNAGLAGNAGLAGN-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------TEQAPAPPPVQASAPQ------- Mb3538|M.bovis_AF2122/97 NAGIG-------------------------------------------GT Rv3508|M.tuberculosis_H37Rv SAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGA MUL_4367|M.ulcerans_Agy99 TSGVG-------------------------------------------GA MMAR_2100|M.marinum_M PEGQT-------------------------------------------GM Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GH----------------------------------------------GG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAG----------------- Rv3508|M.tuberculosis_H37Rv GGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKA MUL_4367|M.ulcerans_Agy99 GGAGGNGGNAGFGVSAGG----TGGSAGDGGAG----------------- MMAR_2100|M.marinum_M QGVGGAGGDGGLGGQAGNGSDGADAIVGGGKGG----------------- Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFGK-----GGNAGNGADG----------------- Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFGR-----GGNAGNGGNG----------------- MSMEG_0868|M.smegmatis_MC2_155 AAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKA----------------- TH_3810|M.thermoresistible__bu ---------------ESHTP----GVYTDRQ------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGN-----AGLAGNAGLA----------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPP----------------- Mb3538|M.bovis_AF2122/97 GEGGAGGNSGVGGTNGSGGAG---------GAGGKGGTGGAGGSGADNPT Rv3508|M.tuberculosis_H37Rv GDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSIN MUL_4367|M.ulcerans_Agy99 --GGAGGVDGVGGASGNGGAA---------GAGGAGGSGIGAG------- MMAR_2100|M.marinum_M -DGGDGGDPGLGGAGGQGGAG--------STAGMEGLTAGDDGP------ Mflv_5091|M.gilvum_PYR-GCK ---GTGGAGGAGGTGGTGGAG----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGNGGNGGTGGTGGNG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 -AGGNGGDGGFNGTGGATG------------------------------- TH_3810|M.thermoresistible__bu ------GEDGEDGTGTGIG------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------GNAGLAGNAGLAGNA----------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----LPEAPPIPAAPPVVPVP----------------------------- Mb3538|M.bovis_AF2122/97 GAGFAGGAGGTGGAAGAGGAG--------------GATGTGGTGGVVGAT Rv3508|M.tuberculosis_H37Rv ANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAA MUL_4367|M.ulcerans_Agy99 IDGGAGGAGGTGGAAGFPGGG--------------GTTGAWGTGGAGGAG MMAR_2100|M.marinum_M GHGGDGGAGGDGAAAVTTGSAG----------------GDGGAGGDGGLV Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGIGGAGSTGGTG-----------------GTGGTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGIGGAGSTGGTG-----------------GTGGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 GRGGDGAGASVWKANGQHSTGQT------------DTGGNGGRGGDGGTF TH_3810|M.thermoresistible__bu GRGGNGG-----SSSGTHPMAE---------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAG-----------------NAAVAGNAAVA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VVVPPVPVPVPVRIPVPDPVSP------------------PQLLAPPRLS Mb3538|M.bovis_AF2122/97 GSAGIGGAGGRGGDGGDGASGLG-LGLSGFDGGQGGQGGDGGSAGAGGIN Rv3508|M.tuberculosis_H37Rv GKAGGGGNGGRGGDGGDGASGLG-LGLSGFDGGQGGQGGAGGSAGAGGIN MUL_4367|M.ulcerans_Agy99 GAGGAGDHGGVGVNPGD-------SGTAGWAGGAGGAGGAGGSAAFNGVN MMAR_2100|M.marinum_M GDGGVGGNGGTGADGSPGITFISPGGLSGTDGGAGSIGGTGGAGGAGGLH Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG--------------------GTGGKGGTGGTGGAGGTG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG--------------------GTGGKGGTGGTGGDGGTG MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGGAGGAGGVSEGEGG----TGGHGGDGGRGGDGALGGNGGTG TH_3810|M.thermoresistible__bu -------------------------------DGEHVKALDGRPGLDG--- MAB_4284c|M.abscessus_ATCC_199 GNAAVAGNAAVG--------------------GVLNTGVSGAIGGSSHVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VPQPVQPPVRVP-------------------QPPSPPQVGGTVPQSPPQH Mb3538|M.bovis_AF2122/97 ----GAGGAGGDGGDGGDGATG-----AAGLGDNGGVGGDGGAGGAAGNG Rv3508|M.tuberculosis_H37Rv ----GAGGAGGNGGDGGDGATG-----AAGLGDNGGVGGDGGAGGAAGNG MUL_4367|M.ulcerans_Agy99 ----GAGGAGGNGGAGGGGGAG-----ASGIG-AGVAGGDGGTGGTGG-- MMAR_2100|M.marinum_M AGDGGAGGIGGTGGDGGHGGSGSAGADATIAGAAGQTGGDGGDGGAGGAG Mflv_5091|M.gilvum_PYR-GCK ----GDGGTGGTGGTGGTGGTG----------------GTGGTGGAG--- Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGTGGTGGTG----------------GTGGTGGAG--- MSMEG_0868|M.smegmatis_MC2_155 GVGLGNGGKGGNGGNGGNGGTY----------VDPSHTGAGGNGGNGGAG TH_3810|M.thermoresistible__bu ----GNGSHGGNGGHGGRGG----------------FLGIGGSGGWG--- MAB_4284c|M.abscessus_ATCC_199 G--AINESLGGSGSVGGSTAVG-----------------GGAHTGVG--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 QTPPGEGTPPKPDGPGNYGGGHVP------------TPGAGGSGGSG--- Mb3538|M.bovis_AF2122/97 GNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQG Rv3508|M.tuberculosis_H37Rv GNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQG MUL_4367|M.ulcerans_Agy99 ---------AAGTGGAAGTGGTGGAAGAAGS------------------- MMAR_2100|M.marinum_M GAGGAG-GLAQATGYLDGSHGSGGSGGAGGQAGNAGDGGDG--------- Mflv_5091|M.gilvum_PYR-GCK ----------DGTGGTGGTGGTGGQGGQGGQ------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------DGLGGTGGTGGTGGFGGQGGQ------------------- MSMEG_0868|M.smegmatis_MC2_155 RI-----RVNNGTATGTATGGNGGNGGNG--------------------- TH_3810|M.thermoresistible__bu --------------------GHGGNGGDT--------------------- MAB_4284c|M.abscessus_ATCC_199 -------------GGVSTGVGVGSHVGGGIS------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------GGHVPTPGAGGSGGSGGG------------------- Mb3538|M.bovis_AF2122/97 GLGGASTTSINANGGAGGNGGTGGKGGAGGAG-TLGVGGSGGTGGDGGDA Rv3508|M.tuberculosis_H37Rv GLGGASTTSINANGGAGGNGGTGGKGGAGGAG-TLGVGGSGGTGGDGGDA MUL_4367|M.ulcerans_Agy99 ----------------AGDGGAGGAGGAGDDG-SAGVVS-----GDPGTA MMAR_2100|M.marinum_M ----------------ADATVAGGKGGAGGNGGDAGVGGSGGLGGDSGNG Mflv_5091|M.gilvum_PYR-GCK ----------------GGTGGTGGQGGLGGGG------------------ Mvan_1264|M.vanbaalenii_PYR-1 ----------------GGTGGTGGQGGLGGVG------------------ MSMEG_0868|M.smegmatis_MC2_155 ----------------DADGHRGGKGGDGGEA------------------ TH_3810|M.thermoresistible__bu ----------------DADGGNGGDGGNGG-------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------ESLGGSGSVGGSTAVG------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------HVPTPGTGGPGGTGGSG------------------ Mb3538|M.bovis_AF2122/97 GAGGGGGFGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGG Rv3508|M.tuberculosis_H37Rv GSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGG MUL_4367|M.ulcerans_Agy99 GKAGG-----------AGGAGGVGGN-------------GVAGGVNGSGG MMAR_2100|M.marinum_M THAANG---ASAGAYGTGGNGGAGGDGAD---------ATAAGQAGGAGG Mflv_5091|M.gilvum_PYR-GCK ---------------GTGGQGGTGGT----------------GGQGGTGG Mvan_1264|M.vanbaalenii_PYR-1 ---------------GTGGTGGTGGT----------------GGQGGTGG MSMEG_0868|M.smegmatis_MC2_155 -LIRATVIGSNASGTATGGDGGNGGT---------------LGATNGTGG TH_3810|M.thermoresistible__bu ----------------SAGRGGTGGL---------------RGVF----- MAB_4284c|M.abscessus_ATCC_199 ----------------GGAHTGVGGG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------GGHVPTPGA------------------------ Mb3538|M.bovis_AF2122/97 AGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGP--DGGDGGQGGIGGD Rv3508|M.tuberculosis_H37Rv AGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGP--DGGDGGQGGIGGD MUL_4367|M.ulcerans_Agy99 AG---------GAGGAGGTGGAGASGVPASVDGG---DGGAGGAGGAAGT MMAR_2100|M.marinum_M AGGDGGVVGDGGVGGNGGDGKAGVDGTSAVTFGASGADGGDGGAGGAGGA Mflv_5091|M.gilvum_PYR-GCK TG---------GTGGTGGTGGAGG-------------DGGLGGLGGFGGS Mvan_1264|M.vanbaalenii_PYR-1 TG---------GTGGTGGTGGAGG-------------DGGLGGLGGFGGV MSMEG_0868|M.smegmatis_MC2_155 AATIVAYNVVQANPQASGTATDGH--------------GGSGINGGHGGN TH_3810|M.thermoresistible__bu -----------------------------------------GINGGNGR- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VSTGVGVGSHVGGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------GTPGGSGGG Mb3538|M.bovis_AF2122/97 GGNAGFGAGVPGDGGIGG----------TGGAGGAGGAGGAGDAGADGDP Rv3508|M.tuberculosis_H37Rv GGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDP MUL_4367|M.ulcerans_Agy99 GG--------------------------SGGSAGNTGAGGAG-------- MMAR_2100|M.marinum_M GGDGGAVAGDGGRGGAGG----------DGAMGGNGGNGFDGLHG--TTP Mflv_5091|M.gilvum_PYR-GCK GG--------------------------TGGQGGLGGPGGST-------- Mvan_1264|M.vanbaalenii_PYR-1 GG--------------------------TGGQGGQGGPGGST-------- MSMEG_0868|M.smegmatis_MC2_155 GGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANP TH_3810|M.thermoresistible__bu -----------------------------AGLGGRGXX------------ MAB_4284c|M.abscessus_ATCC_199 ---------------------------ISESLGGSGSVGGST-------- MLBr_01183|M.leprae_Br4923 -----------------------------MPLFLNAEPQALT-------- MAV_4827|M.avium_104 ----------------------------HLPFPGAGSTPG---------- Mb3538|M.bovis_AF2122/97 SIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD Rv3508|M.tuberculosis_H37Rv SIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD MUL_4367|M.ulcerans_Agy99 -------GAGGAGGSAASTGVN---------GDGGAGGAGGVGGLGGDSA MMAR_2100|M.marinum_M GANGQYGGDGGEGGRGGVGGAGGAG-GAAAAGQAGSQGDGGNGGDGGDGG Mflv_5091|M.gilvum_PYR-GCK ------GGAGGAGGQAGTAGKGG--------LFGGSGSAGKAGATGAAGA Mvan_1264|M.vanbaalenii_PYR-1 ------GGAGGAGGQAGVAGKGG--------LFGGSGSAGTAGVTGASGA MSMEG_0868|M.smegmatis_MC2_155 GSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGK TH_3810|M.thermoresistible__bu ----------XXGGGVGAAVRSGNG----VFSGGG--------GTPSAGF MAB_4284c|M.abscessus_ATCC_199 --------AVGGGAHTGVGGGVNTG----------------VGVGSHVGG MLBr_01183|M.leprae_Br4923 ---------AAANTLEGLSAAT---------------------VASNAAA MAV_4827|M.avium_104 ---------GSGGGHLPTPGAGTPG-----------------GGLGGFGG . . Mb3538|M.bovis_AF2122/97 GFIGGSGGTGGTGGDAGAGGLANTGGTAGNAGIGGAGGRGGDGGAGD-SG Rv3508|M.tuberculosis_H37Rv GFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGD-SG MUL_4367|M.ulcerans_Agy99 ATAGG-GGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGS-DG MMAR_2100|M.marinum_M --TPGNGGSGADGANSAIGVSAGDGGYGGAGGNAGAGGLGGEGGAGSTSG Mflv_5091|M.gilvum_PYR-GCK S--GGKGAQGATGAQGATGAQGATGATGAAGKAGATGAAGAAGAAGS-AG Mvan_1264|M.vanbaalenii_PYR-1 S--GGKGAQGATGAQGATGAQGATGATGASGAQGSAGSAGSAGVAGS-AG MSMEG_0868|M.smegmatis_MC2_155 GGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAG TH_3810|M.thermoresistible__bu GVPTT---IQFPAGSCTSRAVSREGIMPSSRAASARAGAACASSTSRSRR MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTS MLBr_01183|M.leprae_Br4923 AQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS--- MAV_4827|M.avium_104 GHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------ . .. . Mb3538|M.bovis_AF2122/97 ALSQDGNGFAGGQGGQGGAGGNA------GAGGINGAGGTGGTGGAGGDG Rv3508|M.tuberculosis_H37Rv ALSQDGNGFAGGQGGQGGVGGNA------GAGGINGAGGTGGTGGAGGDG MUL_4367|M.ulcerans_Agy99 IIPSNG-----GLGGNGGNGGNG------GQAFGDGVGGAGGIGGKGGNA MMAR_2100|M.marinum_M ASGLDGSQAAGGDGGNGGFGGTGGLFEAAGSGGAGGVGGDGSQGGDGGDG Mflv_5091|M.gilvum_PYR-GCK TTGAQGS--AGTNGANGANGSQG------AAGKAGATGTTGATGAAGEDG Mvan_1264|M.vanbaalenii_PYR-1 TTGAQGS--AGTNGANGANGSQG------AAGKAGATGTTGATGAAGDAG MSMEG_0868|M.smegmatis_MC2_155 GFSNIAAIHGAITDSTAISGHGG-----AGNGGNGGKGADGWVQAYDPAG TH_3810|M.thermoresistible__bu SFCCSRA------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AINESMNSSINASHSSSMNESFG------SSMGSHGAAGTGFEAQGHAQG MLBr_01183|M.leprae_Br4923 LLTSSSAYAGTETANHDSL------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 APATLIGGPDGGDGGQGG------------GAGFGSGVAG---------- Rv3508|M.tuberculosis_H37Rv QNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGA MUL_4367|M.ulcerans_Agy99 AIGTIVIN--GGVGGAGG-------------------------------- MMAR_2100|M.marinum_M GAGGSSPGATGGWGGQGG-------------------------------- Mflv_5091|M.gilvum_PYR-GCK DAGSGGSGINGGAGGAGG-------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 DPGSEAVDINGGAGGAGG-------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PVGSKIANSSAVAGNGGD-------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 HASETAHTTLPGAEHH---------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AAGAGGNGGKG-----GDGGTGGTG------------------------- Rv3508|M.tuberculosis_H37Rv AGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M -----------------LGGVGTAG------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------GTNFAGGQGG------------------AGGRGG Rv3508|M.tuberculosis_H37Rv RGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGG MUL_4367|M.ulcerans_Agy99 --------------------------------------------SGGLGG MMAR_2100|M.marinum_M --------------------------------------------VGGHGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------GGVNG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AGGNGANG------------------------------------------ Rv3508|M.tuberculosis_H37Rv AGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIG MUL_4367|M.ulcerans_Agy99 ATEDGVGG------------------------------------------ MMAR_2100|M.marinum_M DGGDAGDS------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGG----------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGD MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2100|M.marinum_M ----------------------------------------------GSSA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 VGDNAAGGDGGNGGAGGLGGG-GGTGGTNGNGGLGGGGGNGGAGGAGGTP Rv3508|M.tuberculosis_H37Rv GGNGGAGGAGGNGGAGGLGGG-GGTGGTNGNGGLGGGGGNGGAGGAGGTP MUL_4367|M.ulcerans_Agy99 --VGCAGGAGGNGGRG------------DMLFTVGGSGGTGGDGGGGGSA MMAR_2100|M.marinum_M FGVGSPGGGGGQGGFGVAGGGDGGDGGNGGAGGFGQNGGPGGRGGGGG-H Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDG-------------GKGGAGAEGGAGGGGGAGG-- Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAG-------------GAGGDGSEGGAGGSGGAGG-- MSMEG_0868|M.smegmatis_MC2_155 ----ASGGDGGNGGNTSVWKS--------GGQTADGEHNTGGNGGNGGDG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 TGSGTEGTGGDGGDAGAGGNGGSA-TGVGNGGNGGDGGNGGDGGN-GAPG Rv3508|M.tuberculosis_H37Rv TGSGTEGTGGDGGDAGAGGNGGSA-TGVGNGGNGGDGGNGGDGGN-GAPG MUL_4367|M.ulcerans_Agy99 SGSGTGGSGGTGGVGGIGGDGK-------LGGFGGDGGDGGDGGF-GVIG MMAR_2100|M.marinum_M SLVGPGGDGGLGGTGGNGGNGSQPPFGSTPAGSGGDGGNGGAGGSSGFVS Mflv_5091|M.gilvum_PYR-GCK --SGAGGAGGAGGSGGSG-------------GSGGSGGSGGAAGD----- Mvan_1264|M.vanbaalenii_PYR-1 --SGTGGAGGAGGSGGSG-------------GSGGAGGSGGAAGD----- MSMEG_0868|M.smegmatis_MC2_155 SEPGPGGNGA-GGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGT----- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS Rv3508|M.tuberculosis_H37Rv GFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS MUL_4367|M.ulcerans_Agy99 GQGGGGGFGGLGGTGAGG-APSDKGINGEPGNPG- MMAR_2100|M.marinum_M GQSGTDGQDGGDPSGQFGGTGGAGGSGGAGAGT-- Mflv_5091|M.gilvum_PYR-GCK ---------------------SDD----------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------SD------------ MSMEG_0868|M.smegmatis_MC2_155 --------------------PGTAGTTGANNP--- TH_3810|M.thermoresistible__bu ----------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------- MLBr_01183|M.leprae_Br4923 ----------------------------------- MAV_4827|M.avium_104 -----------------------------------