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MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLVAAQDEVSTAIAALFGSHGQHYQAISAQVAA YQERFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGN GGNSGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGNGGIGGAGTN LAIGGHGGNGGNAGLIGAGGTGGAGGTGGGEPSAGASGGNGGNGGNGGLLIGNSGDGGAAGNGAGISQNG PASGFGGNGGHAGTTGLIGNGGNGGAGGAGGDVSADFGGVGFGGQGGNGGAGGLLYGNGGAGGNGGAAGS PGSVTAFGGNGGSGGSGGNGGNALIGNAGAGGSAGAGGNGASAGTAGGSGGDGGKGGNGGSVGLIGNGGN GGNGGNGGAGSLFNGAPGFGGPGGSGGASLLGPPGLAGTNGADG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2648c | PE_PGRS45 | - | 100% (464) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1431c | PE_PGRS25 | e-137 | 57.59% (474) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0593c | PE_PGRS7 | e-132 | 50.81% (553) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-81 | 46.50% (428) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2615c | PE_PGRS45 | 0.0 | 98.71% (464) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-09 | 38.71% (93) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-41 | 32.55% (467) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3316 | - | 1e-136 | 53.58% (517) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 3e-22 | 42.11% (171) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-65 | 40.00% (460) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-44 | 40.72% (307) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0212 | - | 1e-128 | 53.15% (508) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-79 | 47.86% (374) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2648c|M.bovis_AF2122/97 --------------------------------------------------
Rv2615c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3316|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb2648c|M.bovis_AF2122/97 --------------------------------------------------
Rv2615c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3316|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb2648c|M.bovis_AF2122/97 ------------------------------------MSFVNVAP------
Rv2615c|M.tuberculosis_H37Rv ------------------------------------MSFVNVAP------
MMAR_3316|M.marinum_M ------------------------------------MAFVLVAP------
MUL_0212|M.ulcerans_Agy99 ------------------------------------MSFVNVTP------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------MNIVLGVS------
Mb2648c|M.bovis_AF2122/97 ----------------------------------------QLVSTAAADA
Rv2615c|M.tuberculosis_H37Rv ----------------------------------------QLVSTAAADA
MMAR_3316|M.marinum_M ----------------------------------------EMVTAAASDL
MUL_0212|M.ulcerans_Agy99 ----------------------------------------EAVAAAASDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------------MAPSSIQMVVL
Mb2648c|M.bovis_AF2122/97 AR----------------------IGSAIN-----------TAN-TAAAA
Rv2615c|M.tuberculosis_H37Rv AR----------------------IGSAIN-----------TAN-TAAAA
MMAR_3316|M.marinum_M AN----------------------IGSAIN-----------TANTAVAAP
MUL_0212|M.ulcerans_Agy99 TG----------------------IGSVLG-----------EANAVAARA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ANAG----------------LSAVSAAQVG---------AVMPVVAESVA
MLBr_01183|M.leprae_Br4923 ------------------------------------------------MP
MAV_4827|M.avium_104 EG-----------------------EYADG-----------ATVEEDAID
Mb2648c|M.bovis_AF2122/97 TT-------QVLVAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVL
Rv2615c|M.tuberculosis_H37Rv TT-------QVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVL
MMAR_3316|M.marinum_M TA-------ELLAAGTDEVSEAIASLFSGHALDYQNLGARMTAFHDQFVA
MUL_0212|M.ulcerans_Agy99 TT-------TVLAAGGDEVSAAIAALFSFHGQSYQTLGAQAEAFHAQFAQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu -------------VDGDGGSGGRTGLFS-----------KLSRGGDGGDG
MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL
MLBr_01183|M.leprae_Br4923 ---------LFLNAEPQALTAAANTLEG--------LSAATVASNAAAAQ
MAV_4827|M.avium_104 VTG---ADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
Mb2648c|M.bovis_AF2122/97 ALSQAGSTYA--------VAEAASATPLQNVLDAIN------APVQSLTG
Rv2615c|M.tuberculosis_H37Rv ALSQAGSTYA--------VAEAASATPLQNVLDAIN------APVQSLTG
MMAR_3316|M.marinum_M ALTAGGGLYS--------SAEAAAATPLQDLLNVVN------APTQALLG
MUL_0212|M.ulcerans_Agy99 LMANGAGTYA--------SAEAANAAPFQGLLGAVN------APVQTLTG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GLGGNGGHGG--------------GTGIISLLSLAG-----------NGG
MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLD----LSFGDLQFGN
MLBr_01183|M.leprae_Br4923 LTTEIAPPAA-------------DDVSIL-LAHFFS-----------GHG
MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTA
. .
Mb2648c|M.bovis_AF2122/97 RP--LIGDGAN---------------------------------------
Rv2615c|M.tuberculosis_H37Rv RP--LIGDGAN---------------------------------------
MMAR_3316|M.marinum_M RP--LIGDGADGTAPGQAGGAGGLLYGNGGNGAAGTNPGVAGGAGGAAGL
MUL_0212|M.ulcerans_Agy99 RP--LIGNGAN---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu NGGN----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDS------------N
MLBr_01183|M.leprae_Br4923 RQ------------------------------------------------
MAV_4827|M.avium_104 TLAVVETSDGS---------------------------------------
Mb2648c|M.bovis_AF2122/97 ----------GIDGTGQ------------AGGNGG---------------
Rv2615c|M.tuberculosis_H37Rv ----------GIDGTGQ------------AGGNGG---------------
MMAR_3316|M.marinum_M IGNGGAGGIGGAGGSGG------------AGGTGG---------------
MUL_0212|M.ulcerans_Agy99 ----------GAPGTGA------------NGGAGG---------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu ----------GYRTTDN---------------------------------
MAB_4284c|M.abscessus_ATCC_199 IINADHGSNVGVDQSQTR-----------VGGDYTN--------------
MLBr_01183|M.leprae_Br4923 -----------YQAHAS---------------------------------
MAV_4827|M.avium_104 -------IPDVYKQQIR---------------------------------
Mb2648c|M.bovis_AF2122/97 WLWGNGGNS------GSG---APGQA--------------------GGAG
Rv2615c|M.tuberculosis_H37Rv WLWGNGGNG------GSG---APGQA--------------------GGAG
MMAR_3316|M.marinum_M WLYGNGGAG------GAGGAGAPGLVSF-----------NGSNGGNGGNG
MUL_0212|M.ulcerans_Agy99 WLIGNGGAG------GSG---APGLN--------------------GGAG
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ----NALDG-----------------------------------GHGGNG
MAB_4284c|M.abscessus_ATCC_199 -VSGHGSADIDKSVTVVDDHSQRNTTN----------------INDSFNT
MLBr_01183|M.leprae_Br4923 ----------------------------------------------QGAT
MAV_4827|M.avium_104 -AESYGDAAGQLSAMVAGLEKLESLPGG--------------LLLVGSGV
Mb2648c|M.bovis_AF2122/97 GAAGLIGNGGAG--------------GAGGQGLPFEAG------------
Rv2615c|M.tuberculosis_H37Rv GAAGLIGNGGAG--------------GAGGQGLPFEAG------------
MMAR_3316|M.marinum_M GAAGWWGTGGAG--------------GAGGEGGAAGGGPAGIAYGQTGGV
MUL_0212|M.ulcerans_Agy99 GAAGLIGTGGAG--------------GAGGSSSTVNGG------------
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETG------------
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETG------------
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDG------------
TH_3810|M.thermoresistible__bu GNVGFFSLFNLG--------------GAGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 DRSTNIGSGNTTN-------------TEIGSHNQANIG------------
MLBr_01183|M.leprae_Br4923 NHQDLIQSLLTS---------------SSAYAGTETAN------------
MAV_4827|M.avium_104 DVAPLKQVLQTTTFLDVS--------VAEEPETALARG------------
.
Mb2648c|M.bovis_AF2122/97 -ANGGAGGAGGWLFGNGG-AGGNGGIGG---AGTNLAIGG-------HGG
Rv2615c|M.tuberculosis_H37Rv -ANGGAGGAGGWLFGNGG-AGGNGGIGG---AGTNLAIGG-------HGG
MMAR_3316|M.marinum_M GGNGGNGGNGGWFAGNAG-AGGNGGVGGDGNAADNGLVGGTGG----VGG
MUL_0212|M.ulcerans_Agy99 --LGGTGGAGGWLLGNGG-AGGAGGASAIPLGPD--LIG--------KGG
Mflv_5091|M.gilvum_PYR-GCK -TTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGG
Mvan_1264|M.vanbaalenii_PYR-1 -VTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGG
MSMEG_0868|M.smegmatis_MC2_155 -GTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAG
TH_3810|M.thermoresistible__bu --VDVVGG------NPDGGTPGAHGESHTPG-------------------
MAB_4284c|M.abscessus_ATCC_199 --TSTSAGGSAAVGGNAGLAGNAGLAGNAGLAGNAGLAGNAG----LAGN
MLBr_01183|M.leprae_Br4923 --HDSL--------------------------------------------
MAV_4827|M.avium_104 ---AALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPG
Mb2648c|M.bovis_AF2122/97 NG-------------GNAGLIGAGGTGGAGGTGG----------------
Rv2615c|M.tuberculosis_H37Rv NG-------------GNAGLIGAGGTGGAGGTGG----------------
MMAR_3316|M.marinum_M AG-------------GSAGLFGDGGAGGQGGDGGGVTG------------
MUL_0212|M.ulcerans_Agy99 AG-------------GPGGLFGAGGLGGAGGFGG----------------
Mflv_5091|M.gilvum_PYR-GCK QG-------------LQGGKGGDGGAGGKGGDADSMGS------------
Mvan_1264|M.vanbaalenii_PYR-1 QG-------------LQGGQGGDGGTGGTGGDATSMGE------------
MSMEG_0868|M.smegmatis_MC2_155 YGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAI
TH_3810|M.thermoresistible__bu ---------------VYTDRQGEDGEDGTG--------------------
MAB_4284c|M.abscessus_ATCC_199 AG-----------LAGNAGLAGNAGLAGNAGLAGNAG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DD-----------ELAYSAVGEEDAESPTVVIEKLFLP------------
Mb2648c|M.bovis_AF2122/97 --------------------------------------------GEPSAG
Rv2615c|M.tuberculosis_H37Rv --------------------------------------------GEPSAG
MMAR_3316|M.marinum_M -------LVGAGHGGAGGDGGRAGWLS-----------------GNAGAG
MUL_0212|M.ulcerans_Agy99 -----------SGGGAGGQGGAGGLLS-----------------GLVGAG
Mflv_5091|M.gilvum_PYR-GCK ------AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG
Mvan_1264|M.vanbaalenii_PYR-1 ------AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNG
TH_3810|M.thermoresistible__bu ----------------------------------------------TGIG
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------LAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------EDSEPR
Mb2648c|M.bovis_AF2122/97 AS------------------------------------------------
Rv2615c|M.tuberculosis_H37Rv AS------------------------------------------------
MMAR_3316|M.marinum_M GGGGAGGAVDN------------HGSGGDYAGGGGAGGSGGAAGLFGNGA
MUL_0212|M.ulcerans_Agy99 GG---------------------HGGTGGYGGG-----------------
Mflv_5091|M.gilvum_PYR-GCK AD----------------------GGTGGAGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1 GN----------------------GGTGGNGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 GNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGA-----------
TH_3810|M.thermoresistible__bu GR------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GN------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 RRP-----------------------------------------------
Mb2648c|M.bovis_AF2122/97 ---------------------------GGNGGNGGNG--GLLIGNSGDGG
Rv2615c|M.tuberculosis_H37Rv ---------------------------GGNGGNGGNG--GLLIGNSGDGG
MMAR_3316|M.marinum_M AGGAGGAGGASQTF----------TGAGGAGGTGGAG--GWLYGNGGAGG
MUL_0212|M.ulcerans_Agy99 AGGAGATGGG---------------NTGGIGGDGGSA--GMLFSNSGAGG
Mflv_5091|M.gilvum_PYR-GCK TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGG
TH_3810|M.thermoresistible__bu ---------------------------GGNGG-SSSGTHPMAEDGEHVKA
MAB_4284c|M.abscessus_ATCC_199 ------------------------AGLAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------VLLVGSGLAVVGISAVLALEIALAIGIR
Mb2648c|M.bovis_AF2122/97 AAGNGAGISQNGPASGFG--GNGGHAGTTGLIGNGGNG----GAGG----
Rv2615c|M.tuberculosis_H37Rv AAGNGAGISQNGPASGFG--GNGGHAGTTGLIGNGGNG----GAGG----
MMAR_3316|M.marinum_M AGGASGAGIGGDSLGGSG--GNGGNGGISGLIGNGGAG----GAGGNGSA
MUL_0212|M.ulcerans_Agy99 AGGASELADGG--AGGAG--GNGG-----WLLSNGGVG----GAGG----
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG-GTGGTGGTG--GTGGKGGTGGTGGAGGTG----GDGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG-GTGGTGGTG--GTGGKGGTGGTGGDGGTG----GTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 AGGAGGVSEGEGGTGGHG--GDGGRGGDGALGGNGGTGGVGLGNGGKG--
TH_3810|M.thermoresistible__bu LDGRPGLDGGNGSHGGNG--GHGGRGGFLGIGGSGGWG------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGN----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKP--
Mb2648c|M.bovis_AF2122/97 ----------------------------------AGGDVS---------A
Rv2615c|M.tuberculosis_H37Rv ----------------------------------AGGDVS---------A
MMAR_3316|M.marinum_M AGYNGYSGNGGNGGNGGAAQLIGAGGGGGVAGIGGAGGTG---------A
MUL_0212|M.ulcerans_Agy99 ---------------------------------AGADAVG---------P
Mflv_5091|M.gilvum_PYR-GCK -------------------------------GTGGTGGTG---------G
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------GTGGTGGTG---------G
MSMEG_0868|M.smegmatis_MC2_155 -------------------------------GNGGNGGNGGTYVDPSHTG
TH_3810|M.thermoresistible__bu ----------------------------------GHGGNG----------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------AAVAGNAAVG---------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------LSPPVAAP--------LP
Mb2648c|M.bovis_AF2122/97 DFGGVGFGGQG--------------------------------GNGGAGG
Rv2615c|M.tuberculosis_H37Rv DFGGVGFGGQG--------------------------------GNGGAGG
MMAR_3316|M.marinum_M AAGVTGSAGASGVGGRLYSGNGIPDIFGRPLIGDGADGAPGTGQAGGDGG
MUL_0212|M.ulcerans_Agy99 PFGIPAGSGSG-------------------------------GGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGAG----------------------------DGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGAG----------------------------DGLGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGNGGAGRIR-----------------VNNGTATGTATGGNGGNGG
TH_3810|M.thermoresistible__bu -GDTDADGGNG--------------------------------GDGGNGG
MAB_4284c|M.abscessus_ATCC_199 VLNTGVSGAIG--------------------------------GSSHVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AAPPPAAPPLP------------------------------EAPPIPAAP
Mb2648c|M.bovis_AF2122/97 ------LLYGNGGAGG----------------------------------
Rv2615c|M.tuberculosis_H37Rv ------LLYGNGGAGG----------------------------------
MMAR_3316|M.marinum_M ------WLYGNGGAGGSGAAGQAGGAGGAAGLIGNGGAGGTGGSGAAGGS
MUL_0212|M.ulcerans_Agy99 ------VFFGNGGAGG------AGGTG--------GDGGGTGGAGGAAGN
Mflv_5091|M.gilvum_PYR-GCK ----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGT
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGT
MSMEG_0868|M.smegmatis_MC2_155 NGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGT
TH_3810|M.thermoresistible__bu -------SAGRGGTGG----------------------------------
MAB_4284c|M.abscessus_ATCC_199 --AINESLGGSGSVGG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVVPVPVVVPPVPVPVPVR-------------------------------
Mb2648c|M.bovis_AF2122/97 ---------------------------------------NGGAAGSP---
Rv2615c|M.tuberculosis_H37Rv ---------------------------------------NGGAAGSP---
MMAR_3316|M.marinum_M GAAGGNGGAGGWLFGNGGTGGTGGDAVAGLPGLNGGNGGNGGAGGAAGWW
MUL_0212|M.ulcerans_Agy99 GVLIGNG-------------------------------GNGGIGGAAGLW
Mflv_5091|M.gilvum_PYR-GCK G-------------------------------------GQGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 G-------------------------------------GTGGTGGTGGQG
MSMEG_0868|M.smegmatis_MC2_155 GGAATIVAYNV--------------VQANPQASGTATDGHGGSGINGGHG
TH_3810|M.thermoresistible__bu ---------------------------------------LRGVFGINGGN
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------STAVGGGAHTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------IPVPDPVSPPQLL
Mb2648c|M.bovis_AF2122/97 --GSVTAFGGNG--------------------------------------
Rv2615c|M.tuberculosis_H37Rv --GSVTAFGGNG--------------------------------------
MMAR_3316|M.marinum_M GHGGIGGQGGTGGAAGGNPGIYAGNAGTGGDGGAGGWLFGDAGAGGQGGT
MUL_0212|M.ulcerans_Agy99 GTGGTGGSGGSG--------------GTGATGGFSG--------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF-------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF-------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN-------------
TH_3810|M.thermoresistible__bu GRAGLGGRGXXX--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVGVG--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APPRLSVPQPVQP-------------------------------------
Mb2648c|M.bovis_AF2122/97 --------------GSGGSGGNGGNA------------------------
Rv2615c|M.tuberculosis_H37Rv --------------GSGGSGGNGGNA------------------------
MMAR_3316|M.marinum_M GGAANDPLVTSSTGGSGGAGGNGGAAGLFGAGGAGGTGGTAGDGYLIGGD
MUL_0212|M.ulcerans_Agy99 -------LLASGDGGAGGAGGAGGAGGLLDG--------------LVGAG
Mflv_5091|M.gilvum_PYR-GCK -GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGS
Mvan_1264|M.vanbaalenii_PYR-1 -GGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGS
MSMEG_0868|M.smegmatis_MC2_155 -GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGY
TH_3810|M.thermoresistible__bu ---------------XGGGVGAAVRS------------------------
MAB_4284c|M.abscessus_ATCC_199 --SHVGGGISESLGGSGSVGGSTAVGGG--------------------AH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------PVRVPQPPSPPQVGGTVPQSPPQHQTP--------------PGE
Mb2648c|M.bovis_AF2122/97 ------------LIGNAGAGGSAGAGGNG-----ASAGTAGGSGGDG---
Rv2615c|M.tuberculosis_H37Rv ------------LIGNAGAGGSAGAGGNG-----ASAGTAGGSGGDG---
MMAR_3316|M.marinum_M GGNGGQGGYGGWLAGSGGAGGTAGDGGAG-----IYPGGAGGTGGSGGAA
MUL_0212|M.ulcerans_Agy99 GGDGGAGGNAGTLFGSGGVG---GDGGSG-----HGNGGDG--GGGGNAG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG
TH_3810|M.thermoresistible__bu --------------GNGVFSGGGGTPSAG-------FGVPTTIQFPAG--
MAB_4284c|M.abscessus_ATCC_199 TGVGGGVSTGVGVGSHVGGGISESLGGSG------SVGGSTAVGGGAHTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTPPKPDGPGNYGGGHVPTPGAGGSGGSG--------GGHVPTPGAGGSG
Mb2648c|M.bovis_AF2122/97 -----------------------------GKGGNGGSVG----LIGNGGN
Rv2615c|M.tuberculosis_H37Rv -----------------------------GKGGNGGSVG----LIGNGGN
MMAR_3316|M.marinum_M RFFGDGGAAGTGGVGGFGSKY------VAGSGGSGGTGGAAGWLIGNGGA
MUL_0212|M.ulcerans_Agy99 LLFSD---AGGGGFGGFG---------LAGGGGTGGSGGDAGWLG-SGGA
Mflv_5091|M.gilvum_PYR-GCK GATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGA
TH_3810|M.thermoresistible__bu -------------------------------SCTSRAVSREGIMPSSRAA
MAB_4284c|M.abscessus_ATCC_199 VGGGVNTGVGVGSHVG---------------GGISESLGGSGSVGGSTAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GSGGGHVPTP-------------------GTGGPGGTGGSGGGHVPTPGA
Mb2648c|M.bovis_AF2122/97 G-----------------------GNGGNGGAGSLFNGAPGFGGPG----
Rv2615c|M.tuberculosis_H37Rv G-----------------------GNG---GAGSLFNGAPGFGGPG----
MMAR_3316|M.marinum_M GGQGGVAGTPDGVNRVFG---GTGGAGGTGGTAGWLYGSGGSGGAGGA--
MUL_0212|M.ulcerans_Agy99 GGAGGIS-----VN-------GDAGAGGAGGTSGQLLGDGGAGGAG----
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTS
TH_3810|M.thermoresistible__bu S-----------------------ARAGAACASSTSRSRRSFCCSRA---
MAB_4284c|M.abscessus_ATCC_199 G-----------------------GGAHTSAINDALGGSGSVGGSTAVG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 G-----------------------TPGGSGGGHLPFPGAGSTPGGSG---
Mb2648c|M.bovis_AF2122/97 ----------------GSGG----ASLLGP-----PGLAGTNGADG----
Rv2615c|M.tuberculosis_H37Rv ----------------GSGG----ASLLGP-----PGLAGTNGADG----
MMAR_3316|M.marinum_M --GTASIYPGSTGGNGGNGGNGGAAQVIGT-----GGTGGTAGTGG--AG
MUL_0212|M.ulcerans_Agy99 --GEAELAAG---GAGGSGGVGGDAVLIGA-----GGNGGNGGPGT--AK
Mflv_5091|M.gilvum_PYR-GCK --------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------GGAHTSAINESMNSSINASHSSSMNESFGSSMGSH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------GGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGG
Mb2648c|M.bovis_AF2122/97 -----------------------------------
Rv2615c|M.tuberculosis_H37Rv -----------------------------------
MMAR_3316|M.marinum_M GPDDPPNNIPAGNDGQDGVGGAGGSGGLVFGNSGG
MUL_0212|M.ulcerans_Agy99 G--DP------GSGGAGGLLGVDGLNGLS------
Mflv_5091|M.gilvum_PYR-GCK GAG--GAGGSGGSGGSGGSGGSGGAAGDSDD----
Mvan_1264|M.vanbaalenii_PYR-1 GAG--GAGGSGGSGGSGGAGGSGGAAGDSD-----
MSMEG_0868|M.smegmatis_MC2_155 GSGNGGNGGNGGNGGADGTPGTAGTTGANNP----
TH_3810|M.thermoresistible__bu -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAAGTGFEAQGHAQGHASETAHTTLPGAEHH----
MLBr_01183|M.leprae_Br4923 -----------------------------------
MAV_4827|M.avium_104 GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-----