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SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAY QQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNG GNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTT ITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFVTNFDS NTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0978c | PE_PGRS17 | - | 100% (331) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0980c | PE_PGRS18 | e-142 | 65.92% (446) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv2615c | PE_PGRS45 | e-102 | 73.65% (277) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1003c | PE_PGRS17 | 1e-176 | 93.73% (335) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-20 | 52.81% (89) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 4e-10 | 39.78% (93) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 6e-14 | 43.09% (123) | hypothetical protein MAB_0321c |
| M. marinum M | MMAR_4561 | - | 6e-69 | 52.01% (273) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 2e-16 | 32.33% (266) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 7e-23 | 45.06% (162) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 4e-16 | 33.33% (219) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 3e-65 | 63.08% (214) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_3865 | - | 3e-25 | 42.77% (173) | hypothetical protein Mvan_3865 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_5091|M.gilvum_PYR-GCK ----MVTFGGGATPTPTSLGAAAVDLSGTSCG---LICNGQDGTGQNGGI
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 ------------MSYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv -------------------------------------------MSFVNVA
Mb1003c|M.bovis_AF2122/97 -------------------------------------------MSFVNVA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_5091|M.gilvum_PYR-GCK LFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAG
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu ---------------------------------------------MPFIT
MMAR_4561|M.marinum_M ------------------MSYLFAAPELVASAATDLAGIGSSINAASVAA
MUL_0572|M.ulcerans_Agy99 VMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv PQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSH
Mb1003c|M.bovis_AF2122/97 PQLVSTAAADAARIGSAINTANTAAAATTQVLVAAQDEVSTAIAALFGSH
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mflv_5091|M.gilvum_PYR-GCK AFALFGNGGNGGNGGVGVVGATGAVGAPGVAGATGATGVTSG---VVGGN
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu SGAAFVGGAAMLLAGPGGVSALEAAGSAPRTVEYEYSLVACDSTLPLMCE
MMAR_4561|M.marinum_M AAPTTGVLAAGADEISAAVAGMFAAHAQAYQALSQQADTFHAQFVQLLNS
MUL_0572|M.ulcerans_Agy99 AAEAANASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGLAGTGAAGGA
MLBr_01183|M.leprae_Br4923 ------------------------------------------MPLFLNAE
MAV_1346|M.avium_104 ------------------------------------------MS-FVTTR
Rv0978c|M.tuberculosis_H37Rv GQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQN--------
Mb1003c|M.bovis_AF2122/97 GQHYQAISAQVAAYQERFVLALSQAGSTYAVAEAASATPLQQIE------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mflv_5091|M.gilvum_PYR-GCK GEDAVGYGATGAAGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPG
Mvan_3865|M.vanbaalenii_PYR-1 --------------MIDRLLALLRPTSRVSLLSP----------------
TH_4332|M.thermoresistible__bu AGDSVGGLGGASHDRSAFSASALGMASFGPDWNP----------------
MMAR_4561|M.marinum_M GASAYTGAEAANVSPLQQALDAVNAPVQQLTGRPLIGNGADG--------
MUL_0572|M.ulcerans_Agy99 GGLLWGNGGNGGSGAAGQAGGAGGAAGLIGTGGAGGMGGAGG--------
MLBr_01183|M.leprae_Br4923 PQALTAAANTLEGLSAATVASNAAAAQLTTEIAP----------------
MAV_1346|M.avium_104 PEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAP----------------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mflv_5091|M.gilvum_PYR-GCK ---------KAGDAGGAGAVGAAGAAGTVG-----------TAGATGGTG
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------GAGGMG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv ------------------------VLDAINAPVQSLTGRPLIG-------
Mb1003c|M.bovis_AF2122/97 ----------------------QALLGVINTPTEALVGRKLIG-------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------MANIISNGPDG-------
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL
Mflv_5091|M.gilvum_PYR-GCK TGANGGAG----GVGGVG----GTGAAGAAGGAGGLGETGTTG-------
Mvan_3865|M.vanbaalenii_PYR-1 ----------------------TGAFLGLIGPGGLLIGNGVLP-------
TH_4332|M.thermoresistible__bu ----------------------GGAFLGLIGPGGLLIGDGLNG-------
MMAR_4561|M.marinum_M ----------------------INGTGQSGGDGGWLLGNGGNGG------
MUL_0572|M.ulcerans_Agy99 GSGGWLLGNGGAGGAGGVGCAGVSGGVGGTGGNAMLFGNGGAG-------
MLBr_01183|M.leprae_Br4923 ---------------------------PAADDVSILLAHFFSG-------
MAV_1346|M.avium_104 ---------------------------AAADEVSALQAAQFSA-------
:
Rv0978c|M.tuberculosis_H37Rv -------------------DGANGIDGT----------------------
Mb1003c|M.bovis_AF2122/97 -------------------DGAHGAPGT----------------------
MAB_0321c|M.abscessus_ATCC_199 ------------------DAGATGAQGS----------------------
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
Mflv_5091|M.gilvum_PYR-GCK ------------------GAGGVGGQGTAG--------------GTGGVG
Mvan_3865|M.vanbaalenii_PYR-1 ------------------GQNGGLLIGN----------------------
TH_4332|M.thermoresistible__bu ------------------TDAYIDENGVFH--------------------
MMAR_4561|M.marinum_M ----------------SGAAGQAGGNGGSAG-------------------
MUL_0572|M.ulcerans_Agy99 ------------------GMGGAGADGAVGAAG-----------------
MLBr_01183|M.leprae_Br4923 -------------------HGRQYQAHA----------------------
MAV_1346|M.avium_104 -------------------YGTWYQQVS----------------------
Rv0978c|M.tuberculosis_H37Rv ----------------GQAGGNGGWLWGN---------------GGNGGS
Mb1003c|M.bovis_AF2122/97 ----------------GQAGGAGGILWGN---------------GGNGGS
MAB_0321c|M.abscessus_ATCC_199 ---------------QGATGAAGAMANCN---------------WIDDDC
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
Mflv_5091|M.gilvum_PYR-GCK GIGG-----------AGSTGAVGGVGGKG----------------IQGGQ
Mvan_3865|M.vanbaalenii_PYR-1 ----------------GADGAPG---------------------------
TH_4332|M.thermoresistible__bu ---------------EATRGGNGGLLWGN---------------------
MMAR_4561|M.marinum_M ------------LLGNGGAGGAGGAGASG----------------AAGDS
MUL_0572|M.ulcerans_Agy99 --------------TAGTSTSAGGVGGAGWDATAAGVLAATGGDGGDSGG
MLBr_01183|M.leprae_Br4923 ----------------SQGATNHQDLIQS-------------------LL
MAV_1346|M.avium_104 ----------------AQAKAIHQTLVQN-------------------LD
.
Rv0978c|M.tuberculosis_H37Rv GAPGQAGGAGGAAG------------------------------------
Mb1003c|M.bovis_AF2122/97 GAPGQAGGAGGAAG------------------------------------
MAB_0321c|M.abscessus_ATCC_199 ATRGGTGGTGGNGG------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
Mflv_5091|M.gilvum_PYR-GCK GLQGGKGGDGGAGGKG---------------------------------G
Mvan_3865|M.vanbaalenii_PYR-1 VLPGEAGGKGGNGG------------------------------------
TH_4332|M.thermoresistible__bu ---GGKGGNGLDAG------------------------------------
MMAR_4561|M.marinum_M GLTGGNGGIGGAGG------------------------------------
MUL_0572|M.ulcerans_Agy99 GGAGGNGGAGGAGGHG----------------------------------
MLBr_01183|M.leprae_Br4923 TSSSAYAGTETAN-------------------------------------
MAV_1346|M.avium_104 TNADSYGATEAANR------------------------------------
. ..
Rv0978c|M.tuberculosis_H37Rv -------------LIGNGGAGGTGGAVSLARAGTAGGAG-----------
Mb1003c|M.bovis_AF2122/97 -------------LIGNGGAGGTGGAVSLARAGTAGGAG-----------
MAB_0321c|M.abscessus_ATCC_199 -------------PGGAGGPGGHGGVIDFE--VETFMDG-----------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEG--TGSTAEGTATGGDGGHST
Mflv_5091|M.gilvum_PYR-GCK DADSMGSAGATGGKGGNGGNGGRGGLFGKGGNAGNGADG-----------
Mvan_3865|M.vanbaalenii_PYR-1 ------------LLMGNGGAGGAG---------APGVAG-----------
TH_4332|M.thermoresistible__bu -------------LYTVPDPDNPGSTIQMYFEASDGADG-----------
MMAR_4561|M.marinum_M ---------FLYGLGGNGGIGGHGGDGGAA--IGTGTDG-----------
MUL_0572|M.ulcerans_Agy99 -----SALFGADGANGNGGAGGAGGNPGAPGNGGTGGVG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------VNTSAAALQGLAPNVIPNAAPAADP-----------
Rv0978c|M.tuberculosis_H37Rv --------------------RGPVGGIGGAGG------------------
Mb1003c|M.bovis_AF2122/97 --------------------RGPVGGIGGAGG------------------
MAB_0321c|M.abscessus_ATCC_199 ---------------------VTLQAKGGRGG------------------
MSMEG_0868|M.smegmatis_MC2_155 GTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYS
Mflv_5091|M.gilvum_PYR-GCK ----------------GTGGAGGAGGTGGTGGAGGTGGTGGTGGIG----
Mvan_3865|M.vanbaalenii_PYR-1 ----------------------GAGGAGGNGG------------------
TH_4332|M.thermoresistible__bu ---------------------GRGGFLFGNGG------------------
MMAR_4561|M.marinum_M -------------------GNGGNGGLAGAGG------------------
MUL_0572|M.ulcerans_Agy99 ------------------PDAATSGGMGGTGGDPGAVGGRGNSGAAG---
MLBr_01183|M.leprae_Br4923 -----------------------HDSL-----------------------
MAV_1346|M.avium_104 -------------------PPAGTTSLGTSIG------------------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAK
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 AGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 -------------------------------------GAGAVAGASGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv ----------------------------VGGAGGAAG-------------
Mb1003c|M.bovis_AF2122/97 ----------------------------VGGAGGAAG-------------
MAB_0321c|M.abscessus_ATCC_199 -------------------------------NGGHGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPA
Mflv_5091|M.gilvum_PYR-GCK ------------------------GAGSTGGTGGTGG-------------
Mvan_3865|M.vanbaalenii_PYR-1 ---------------------------FFAGNGGAGG-------------
TH_4332|M.thermoresistible__bu ----------------------------DGGNGGNVGG------------
MMAR_4561|M.marinum_M ------------------------LLFGNGGVGGQGGD------------
MUL_0572|M.ulcerans_Agy99 TIIAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHGGAGGFYGNGGAGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------------------WAQNVGAAAS-------------
Rv0978c|M.tuberculosis_H37Rv ---------AVTTITHASFNDPHGVAVNPGGNVY----------------
Mb1003c|M.bovis_AF2122/97 ---------AVTTITHASFNDPHGVAVNPGGNVY----------------
MAB_0321c|M.abscessus_ATCC_199 ---------AGGTGG----------TGGKGGD------------------
MSMEG_0868|M.smegmatis_MC2_155 GTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQT
Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGTGG-------TGGTGGTGG----------------
Mvan_3865|M.vanbaalenii_PYR-1 ---------AGGNGSTVN----GPTSGGHGGDG-----------------
TH_4332|M.thermoresistible__bu --------KNGADPVTATVAADKSVAGGNGGNG-----------------
MMAR_4561|M.marinum_M --------GGDATGGTATFSGGLAGSGGNGGNG-----------------
MUL_0572|M.ulcerans_Agy99 GGNSAPGGGTGGNGGTGGDSGAMGSSGGRGGDGG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------DFITLGEGQFAPVPGAAGIPNFNPG----------------
Rv0978c|M.tuberculosis_H37Rv ---------------------------------------VTNFGSGTVSV
Mb1003c|M.bovis_AF2122/97 ---------------------------------------VTNFGSGTVSV
MAB_0321c|M.abscessus_ATCC_199 ---------GDDCEFG---------------------RTGGNGGTGGRGG
MSMEG_0868|M.smegmatis_MC2_155 DTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGG
Mflv_5091|M.gilvum_PYR-GCK -TGGTGGKGGTGGTGG-------------------AGGTGGDGGTGGTGG
Mvan_3865|M.vanbaalenii_PYR-1 ---------GKAGLFR------------------------GDGGAGGAGG
TH_4332|M.thermoresistible__bu ---------GRGGLLFG---------------------LGGNGGNGGWST
MMAR_4561|M.marinum_M ---------GQSGWLYG---------------------NGGDGGNSGSGG
MUL_0572|M.ulcerans_Agy99 --VGTNGGAGGGGGNATSYGTANATGGAGGDGGTGSTGNGGSGGDGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------LTAATTAGPPAPAA
Rv0978c|M.tuberculosis_H37Rv INPATN--------------------------------------------
Mb1003c|M.bovis_AF2122/97 INPATN--------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 DGNFAG----TGGNG------------------GAILVKCQHD-------
MSMEG_0868|M.smegmatis_MC2_155 DGALGG----NGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
Mflv_5091|M.gilvum_PYR-GCK TGGTGG----TGGTGGTG---GAGDGTGGTGGTGGTGGQGGQGGQGGTGG
Mvan_3865|M.vanbaalenii_PYR-1 AAVRTG----NGPDG---------------------QVYAGRGGDGGD--
TH_4332|M.thermoresistible__bu TSYLDA----RGGNG-------------------------GNGGLGG---
MMAR_4561|M.marinum_M TFESAGGSVLSGAQG------------------GGFAASAGNGGNSGLFG
MUL_0572|M.ulcerans_Agy99 TGHGGG-----GGPGGTAINYGAGDAFGGAAGKGGTGVVGGNGGSGGAAY
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PAAAAG--------------------------------------------
Rv0978c|M.tuberculosis_H37Rv ---------------------------TVTGSPITIGNGPSG--------
Mb1003c|M.bovis_AF2122/97 ---------------------------TVTGSPITIGNGPSG--------
MAB_0321c|M.abscessus_ATCC_199 --------LSLGT-------------HPMDVSAGTGGNGG----------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGT-------------ATGTATGGNGGNGGNGDADGHRGG
Mflv_5091|M.gilvum_PYR-GCK TGGQGGLGGGGGT-------------GGQGGTGGTGGQGGTG--------
Mvan_3865|M.vanbaalenii_PYR-1 --------AVVGS-------------GGQGGVGGDATSQGGP--------
TH_4332|M.thermoresistible__bu ------VLRPGGL-------------LSLLLPSGAASEPGGL--------
MMAR_4561|M.marinum_M NGGSGGNGGNGGLG------------QAASGDDSQGGIGGDG--------
MUL_0572|M.ulcerans_Agy99 NYGTGNATGAGGSSGSGGAASVPNSASTATATSGSGGAGGDG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------APVLASMGRGPSIGGLS-------
Rv0978c|M.tuberculosis_H37Rv -----------------------VAVSPVTGLVFVTNFDSN---------
Mb1003c|M.bovis_AF2122/97 -----------------------VAVSPVTGLVFVTNFDSN---------
MAB_0321c|M.abscessus_ATCC_199 -----------------------IGGGGGGGGSVGANGAT----------
MSMEG_0868|M.smegmatis_MC2_155 KGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYN
Mflv_5091|M.gilvum_PYR-GCK ----------------------GTGGTGGTGGTGGAGGDGG---------
Mvan_3865|M.vanbaalenii_PYR-1 ----------------------ATSGGGGHGGSVAVFGDAG---------
TH_4332|M.thermoresistible__bu ----------------------FTGGNGGNGGLAIANHWVG---------
MMAR_4561|M.marinum_M ----------------------AQGGNGGKAGFFYGNGGNG---------
MUL_0572|M.ulcerans_Agy99 ----------------------TDGGNGGSGGFAFTFGTGN---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------VPPSWAPGGVAPAANATP---------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 VVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv -----------------------------------------------TVS
Mb1003c|M.bovis_AF2122/97 -----------------------------------------------TVS
MAB_0321c|M.abscessus_ATCC_199 ---------------TGVFSSS--------------------------SD
MSMEG_0868|M.smegmatis_MC2_155 NGGDGIDGGLGGNGGDGVVNTT--------------------------AN
Mflv_5091|M.gilvum_PYR-GCK ------LGGLGGFGGSGGTGGQ--------------------------GG
Mvan_3865|M.vanbaalenii_PYR-1 ---------------DGGFGGY--------------------------AG
TH_4332|M.thermoresistible__bu -------------ITDGVPGPD--------------------------DD
MMAR_4561|M.marinum_M -----------GFGGNGANGGD--------------------------NS
MUL_0572|M.ulcerans_Agy99 --------IIAGVGGGGGTGSTGVGGIGGSGGGADINNGAFTVVPQGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------AQ
Rv0978c|M.tuberculosis_H37Rv VIDPTTNTVTGSPITVG---------------------------------
Mb1003c|M.bovis_AF2122/97 VIDPTTNTVTGSPITVG---------------------------------
MAB_0321c|M.abscessus_ATCC_199 CSGPGPQPNPGSPGDPG-----------------------------TSVA
MSMEG_0868|M.smegmatis_MC2_155 AANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTA
Mflv_5091|M.gilvum_PYR-GCK LGGPGGSTG-GAGGAGG------------------------------QAG
Mvan_3865|M.vanbaalenii_PYR-1 SQNQATGRSGGDGGRGG--------------------------------V
TH_4332|M.thermoresistible__bu AVSSSAYGGHGGHGAGP---------------------------------
MMAR_4561|M.marinum_M GTSSAVNGAGGMGGWGG------------------------------AGG
MUL_0572|M.ulcerans_Agy99 GHGGDGATDGGAGGAGG-----------------------------FTEI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 LVGAGFTSAAPDTAPVT---------------------------------
Rv0978c|M.tuberculosis_H37Rv ---------------TAPTGVAVNPVTGEVYVTNFAGDTVSVIS------
Mb1003c|M.bovis_AF2122/97 ---------------TAPTGVAVNPVTGEVYVTNFAGDTVSVIS------
MAB_0321c|M.abscessus_ATCC_199 VSG---------AQGNPGQAQFLIVP------------------------
MSMEG_0868|M.smegmatis_MC2_155 TAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGAT
Mflv_5091|M.gilvum_PYR-GCK TAGKGGLFGGSGSAGKAGATGAAGASGGKGAQGATGAQGATGAQGATGAT
Mvan_3865|M.vanbaalenii_PYR-1 LSG---------NGGDGGIGGYATSIGTGPAEGGAGGYGGSGGAFSRGGD
TH_4332|M.thermoresistible__bu --------------GSGGNGGSAVANSLGNAIAGNGGDAGRFVLIGPGGN
MMAR_4561|M.marinum_M QAGLIGNGGTGGAGGSGGAGGSGGTENGDAGPGGFGGHGGDALLFGNGGN
MUL_0572|M.ulcerans_Agy99 DSSASVIAATGGAGGDGGSGGTGRGGTGGGGTGGGGTGGGGGVGINNGSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------AVPGGVPSMATAGRGGYGLGAPRYGVKPTVMPKPAI-
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ---GGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDP
Mflv_5091|M.gilvum_PYR-GCK ---GAAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGSQGAAGK
Mvan_3865|M.vanbaalenii_PYR-1 ---GGAGGNGLSATAP----------------------------------
TH_4332|M.thermoresistible__bu ---GGNGGTGLX--------------------------------------
MMAR_4561|M.marinum_M ---GANGGNTGAPGTLSGGGTGTVYLTSNGGDGGQGGIFLGNGANGGAAG
MUL_0572|M.ulcerans_Agy99 EAIGGAPGAGGTGAVGGDGGQGGAAYSYGTGDATGSAGAAGTAGTTGVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 AGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTA
Mflv_5091|M.gilvum_PYR-GCK AGATG--TTGATGAAGEDGDAGSGGSG-INGGAGGAGG-----------A
Mvan_3865|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_4561|M.marinum_M NVPAG---------------------------------------------
MUL_0572|M.ulcerans_Agy99 TGGAGGAAYTLNGASTATATGGIGGNGGDGGTANGSNGGNGGAGGYASTT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1003c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGEHNTGGNGGNGGDGSE-PGPGGNGAGGAGGNGGTGGTTAGGSGNGGNG
Mflv_5091|M.gilvum_PYR-GCK GGEGGEGGDGGKGGAGAE-GGAGGGGGAGGSGAGGAG-------GAGGSG
Mvan_3865|M.vanbaalenii_PYR-1 -GNGGSGGRGGDGGPGGD-GGLGGKGGVGSTN----------------NG
TH_4332|M.thermoresistible__bu ---XXPRPRRRRNHRRTR-RRPNGRRPRPPPGR-----------------
MMAR_4561|M.marinum_M FMAPSLNGIGGDGGDAFL-IGNGGNGGAGAGSD---------------QG
MUL_0572|M.ulcerans_Agy99 GTGTASVGNGGRGGDGTATVATGGTGGVGGNAHAPAG------SPVPGVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv0978c|M.tuberculosis_H37Rv -----------------------
Mb1003c|M.bovis_AF2122/97 -----------------------
MAB_0321c|M.abscessus_ATCC_199 -----------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGADGTPGTAGTTGANNP
Mflv_5091|M.gilvum_PYR-GCK GSGGSGGSGGSGGAAGDSDD---
Mvan_3865|M.vanbaalenii_PYR-1 ADGPDGGPAD-------------
TH_4332|M.thermoresistible__bu -----------------------
MMAR_4561|M.marinum_M GTGGTGGTGGLLLGLPGLEGPA-
MUL_0572|M.ulcerans_Agy99 GKGGNPGPGGKPGPNGADGIVV-
MLBr_01183|M.leprae_Br4923 -----------------------
MAV_1346|M.avium_104 -----------------------