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NRATLEKDPHEVASMFDAVARRYDITNTVLSFGRDRFWRRATREALRLKPGDKVLDIAAGTAVSTAELTQ SGAWCVAADFSVGMLKAGARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREMARVTKPGG RLAVCEFSTPVNRPFRTLYMEYLMKTLPEVARAVSSNPDAYVYLAESIRAWPDQEALAHQIASAGWSNVR WRNLTGGIVALHIATL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3930c | - | - | 100% (227) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. abscessus ATCC 19977 | MAB_3381c | - | 7e-10 | 33.08% (130) | hypothetical protein MAB_3381c |
| M. abscessus ATCC 19977 | MAB_3689 | - | 4e-09 | 38.00% (100) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0573 | ubiE | 1e-99 | 78.48% (223) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. gilvum PYR-GCK | Mflv_5258 | ubiE | 1e-103 | 81.42% (226) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. tuberculosis H37Rv | Rv0558 | ubiE | 1e-99 | 78.48% (223) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. leprae Br4923 | MLBr_02273 | ubiE | 2e-92 | 71.11% (225) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. marinum M | MMAR_0907 | ubiE | 5e-99 | 78.92% (223) | ubiquinone/menaquinone methlytransferase, MenH |
| M. avium 104 | MAV_4584 | ubiE | 2e-99 | 78.67% (225) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1115 | ubiE | 1e-103 | 80.09% (226) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. thermoresistible (build 8) | TH_0087 | - | 1e-09 | 35.04% (117) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_0660 | ubiE | 1e-98 | 78.48% (223) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0983 | ubiE | 1e-105 | 82.30% (226) | ubiquinone/menaquinone biosynthesis methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0573|M.bovis_AF2122/97 -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
Rv0558|M.tuberculosis_H37Rv -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL
MMAR_0907|M.marinum_M -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MUL_0660|M.ulcerans_Agy99 -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL
MAV_4584|M.avium_104 MQRWRRRGIPAPGSVKRVSRAELDKNPRDVASMFDGVARRYDLTNTVLSL
MLBr_02273|M.leprae_Br4923 ---------MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSL
Mflv_5258|M.gilvum_PYR-GCK -----------------MNRASLEKNPHEVASMFDGVARRYDLTNTVLSL
Mvan_0983|M.vanbaalenii_PYR-1 -----------------MNRASLEKDPHEVASMFDGVARRYDLTNTVLSL
MSMEG_1115|M.smegmatis_MC2_155 -----------------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSL
MAB_3930c|M.abscessus_ATCC_199 -----------------MNRATLEKDPHEVASMFDAVARRYDITNTVLSF
TH_0087|M.thermoresistible__bu ----------------------------MLTVDYDRLGIGPGVSVIDVGC
:. :* :. .:: :.
Mb0573|M.bovis_AF2122/97 GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELTKSGAWCVAADFSV
Rv0558|M.tuberculosis_H37Rv GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELTKSGAWCVAADFSV
MMAR_0907|M.marinum_M GQDRYWRRATRSALRIGPGDKVLDLAAGTAVSTVELAKSGAWCVAADFSV
MUL_0660|M.ulcerans_Agy99 GQDRYWRRATRSALRIGPGDKVLDLAAGTAVSSVELAKSGAWCVAADFSV
MAV_4584|M.avium_104 GQDRYWRKATRSALGIGPGQKVLDLAAGTAVSTVELNKSGAWCVAADFSV
MLBr_02273|M.leprae_Br4923 GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTAELSKSGAWCVAADFSV
Mflv_5258|M.gilvum_PYR-GCK GQDRFWRRATREALQLSPADKVLDLAAGTAVSTVELASSGAWCVAADFSV
Mvan_0983|M.vanbaalenii_PYR-1 GQDRFWRRATREALQLSPSDKVLDLAAGTAVSTVELAGSGAWCVAADFSV
MSMEG_1115|M.smegmatis_MC2_155 GQDRFWRRETKSALRIGPADKVLDLAAGTAVSTVELAKSGAWCVAADFSV
MAB_3930c|M.abscessus_ATCC_199 GRDRFWRRATREALRLKPGDKVLDIAAGTAVSTAELTQSGAWCVAADFSV
TH_0087|M.thermoresistible__bu GLGRHSFEAYRRGAHIVAFDQNAEELNEVDTILQAMAEQ-----------
* .*. . : . : . :: : . . : .
Mb0573|M.bovis_AF2122/97 GMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREM
Rv0558|M.tuberculosis_H37Rv GMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREM
MMAR_0907|M.marinum_M GMLAAGHERKVCKVAGDATRLPFADDVFDAVTISFGLRNVVDFSAALREM
MUL_0660|M.ulcerans_Agy99 GMLAAGHERRVCKVAGDATRLPFADDVFDAVTISFGLRNVVDFSAALREM
MAV_4584|M.avium_104 GMLAAGAARRVPKVAGDATRLPFADDVFDAVTISFGLRNVVDTQAALREM
MLBr_02273|M.leprae_Br4923 RMLATGGARKVPKVAADATQLPFSDGVFDAVTISFGLRNIADYQAALREM
Mflv_5258|M.gilvum_PYR-GCK GMLAAGASRRVPKVAGDATRLPFDDGVFDAVTISFGLRNVVDFSAGLREM
Mvan_0983|M.vanbaalenii_PYR-1 GMLAAGAARDVPKVAGDATRLPFADGVFDAVTISFGLRNVVDHSAGLREM
MSMEG_1115|M.smegmatis_MC2_155 GMLAAGASRQVPKVAGDATRLPFADEVFDAVTISFGLRNVVDHKAGLREM
MAB_3930c|M.abscessus_ATCC_199 GMLKAGARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREM
TH_0087|M.thermoresistible__bu --REAPAGARAEVVKGDALDLPYADGTFDRVIASEILEHVPEDDRAIAEL
: . * .** **: * ** * * *.:: : .: *:
Mb0573|M.bovis_AF2122/97 ARVTRPGGRLLVCEFSTPTNALFATAYKEYLMR--------ALPRVARAV
Rv0558|M.tuberculosis_H37Rv ARVTRPGGRLLVCEFSTPTNALFATAYKEYLMR--------ALPRVARAV
MMAR_0907|M.marinum_M ARVTRPGGRLVVCEFSTPVSALFATVYKEYLMR--------ALPRVARAV
MUL_0660|M.ulcerans_Agy99 ARVTRPGGRLVVCEFSTPVSALFATVYKEYLMR--------ALPRVARAV
MAV_4584|M.avium_104 ARVTRPGGRLVVCEFSTPSNALFATVYKEYLMR--------ALPRVARAV
MLBr_02273|M.leprae_Br4923 ARVTRPGGQLVVCEFSTPTNALVANVYTEYLMR--------ALPQVARLV
Mflv_5258|M.gilvum_PYR-GCK ARVTRPGGRLVVCEFSTPTNGLFSTVYKEYLMK--------ALPAMATAV
Mvan_0983|M.vanbaalenii_PYR-1 ARVTRPGGRLVVCEFSTPTNKLFATVYKEYLMR--------ALPAMASAV
MSMEG_1115|M.smegmatis_MC2_155 ARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMK--------ALPAMATAV
MAB_3930c|M.abscessus_ATCC_199 ARVTKPGGRLAVCEFSTPVNRPFRTLYMEYLMK--------TLPEVARAV
TH_0087|M.thermoresistible__bu VRVLKPGGKLVVTVPRWLPERICWLLSDEYHANEGGHVRIYRADELRDKI
.** :***:* * . ** . : :
Mb0573|M.bovis_AF2122/97 SSN-------------PEAYEYLAESIRAWPD--------QAVLAHQISR
Rv0558|M.tuberculosis_H37Rv SSN-------------PEAYEYLAESIRAWPD--------QAVLAHQISR
MMAR_0907|M.marinum_M SSN-------------PEAYVYLAESIRAWPD--------QAALAQQMSR
MUL_0660|M.ulcerans_Agy99 SSN-------------PEAYVYLAESIRAWPD--------QAALAQQMSR
MAV_4584|M.avium_104 SSN-------------PDAYVYLAESIRAWPD--------QAALADQIAG
MLBr_02273|M.leprae_Br4923 SSN-------------PDAYIYLAESIRAWPD--------QVTLACQLSR
Mflv_5258|M.gilvum_PYR-GCK SSN-------------PDAYVYLAESIRAWPD--------QRALARRIEA
Mvan_0983|M.vanbaalenii_PYR-1 SSN-------------PDAYVYLAESIRAWPD--------QAELAARIEA
MSMEG_1115|M.smegmatis_MC2_155 SSN-------------PEAYVYLAESIRAWPT--------QAELARQIGE
MAB_3930c|M.abscessus_ATCC_199 SSN-------------PDAYVYLAESIRAWPD--------QEALAHQIAS
TH_0087|M.thermoresistible__bu TRHGLRLTHRHHAHALHSPFWWLKCAVGTNNDRHFAVRAYHQLLVWDMVR
: : ..: :* :: : : *. :
Mb0573|M.bovis_AF2122/97 ----AGWSGVRWRNLTGGIVALHAGYKPGKQTPQ
Rv0558|M.tuberculosis_H37Rv ----AGWSGVRWRNLTGGIVALHAGYKPGKQTPQ
MMAR_0907|M.marinum_M ----AGWSAVRWRNLTGGIVALHAGYKP---QPV
MUL_0660|M.ulcerans_Agy99 ----AGWSAVRWRNLTGGIVALHAGYKP---QPV
MAV_4584|M.avium_104 ----AGWAGVRWRNLTGGIVALHAAHRP----PR
MLBr_02273|M.leprae_Br4923 ----TGWASPRWRNLTGGIVALHAADKP----VR
Mflv_5258|M.gilvum_PYR-GCK ----AGWSDVRWRNLTGGIVALHAATKP------
Mvan_0983|M.vanbaalenii_PYR-1 ----AGWSDVRWRNLTGGIVALHAATKA------
MSMEG_1115|M.smegmatis_MC2_155 ----AGWSDVRWRNLTGGIVALHAATKPA-----
MAB_3930c|M.abscessus_ATCC_199 ----AGWSNVRWRNLTGGIVALHIATL-------
TH_0087|M.thermoresistible__bu RPWVTRWAEEMLNPLIGKSVALYFDKPEVAGADS
: *: . * * ***: