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MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQIQRDAGVSNGSFFHHFPSKEVLTAAVYVDCVT RYQQALLKDLVRYPDAESAVRGIVGMHLSWCTEHPEMARFLITMTEPAVHRAAADELRSHNERFATAVQT WWRPHAHYGALRPLSPAHSQALWLGPAQELVRAWLLGNLAAPPNAADAAILADAAWLCLRAGPAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0910 | - | - | 100% (205) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_3785 | - | 3e-09 | 28.19% (149) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_5004 | - | 3e-07 | 49.02% (51) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 7e-09 | 30.77% (156) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4630 | - | 3e-09 | 27.43% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 7e-09 | 30.77% (156) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 1e-05 | 39.71% (68) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1552 | - | 2e-26 | 34.39% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1145 | - | 1e-117 | 99.02% (205) | transcriptional regulatory protein |
| M. avium 104 | MAV_1669 | - | 9e-11 | 28.76% (153) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3452 | - | 2e-08 | 30.28% (142) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2070 | - | 2e-06 | 41.18% (51) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 3e-10 | 33.33% (108) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0910|M.ulcerans_Agy99 ------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQ
MMAR_1145|M.marinum_M ------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQ
MAB_1552|M.abscessus_ATCC_1997 --------MIQYSSGVPPASNAGVARRRAILDAALTSFLKSGVAGATVEA
MAV_1669|M.avium_104 ---------------------MKSDRRLQLLSAAERLFAERGFLAVRLED
Mvan_4092|M.vanbaalenii_PYR-1 ---------MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLED
Mb0237|M.bovis_AF2122/97 -------------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNV
Rv0232|M.tuberculosis_H37Rv -------------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNV
MSMEG_3452|M.smegmatis_MC2_155 -----------MANPTRRTRSDALQNRARILEVAAKAFAEQGLD-TAPAA
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
TH_2070|M.thermoresistible__bu -----------------MTNSGPPTRRDELLELAAQMFAERGLKATTVRD
Mflv_4630|M.gilvum_PYR-GCK ----------------MSAEERHRNRRTRLIEAAMELIGTHGVAAATVTA
.* :: * : *
MUL_0910|M.ulcerans_Agy99 IQRDAGVSNGSFFHHFPSKE---VLTAAVYVDCVTRYQQALLKDLVRY-P
MMAR_1145|M.marinum_M IQRDAGVSNGSFFHHFPSKE---VLAAAVYVDCVTRYQQALLKDLARY-P
MAB_1552|M.abscessus_ATCC_1997 LHRESGASVGSIYHFFGSKE---GVAAELYLETLRDYYNAYLAVLQSS-S
MAV_1669|M.avium_104 IGASAGVSGPAIYRHFPNKE---SLLVELLVGISTRLLAGARQVRARS-A
Mvan_4092|M.vanbaalenii_PYR-1 IGAAAGISGPAIYRHFPNKE---ALLVELLVGISTRLLAGAVEVVDRAGD
Mb0237|M.bovis_AF2122/97 IARRAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPN-R
Rv0232|M.tuberculosis_H37Rv IARRAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPN-R
MSMEG_3452|M.smegmatis_MC2_155 IAKLAGVGIGTLYRHFPTRE---TLIDAAYRHQLTRVCDAVADLAARH--
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKE---ALCAAVIGDRMPHLVDDGYVLLKSA-G
TH_2070|M.thermoresistible__bu IADSAGILSGSLYHHFASKE---EMVDEVLRGFLDWLFDRYRSIVETE-P
Mflv_4630|M.gilvum_PYR-GCK VCAESGVTSRYFYQHFPDRD---ALLRAVYQQLYATFQEVIVDAIPDAGA
: :* .::.* : .
MUL_0910|M.ulcerans_Agy99 DAESAVRGIVGMHLSWCTEHPEM--ARFLITMTEPAVHRAAADELRSHNE
MMAR_1145|M.marinum_M DAESAVRGIVGMHLSWCTEHPEM--ARFLITMTEPAVHRAAADELRSHNE
MAB_1552|M.abscessus_ATCC_1997 GPHDGVVGAVSFHLQWVAANEMR--ARFLFHCREFEVIEESRSTITALHE
MAV_1669|M.avium_104 DAAAALDGLIDFHLDFALNEPDL--IRIQDRDLAYLPKPAERQVRKAQRQ
Mvan_4092|M.vanbaalenii_PYR-1 DADSALEGLIDFHLDFVFGEPDL--IRIQDRDLGNLPPAAKRQVRRKQRQ
Mb0237|M.bovis_AF2122/97 PFFEFLTDLLDGWVAYFAEHPRE--RALHAAATLEVDTDARISVRSVLHR
Rv0232|M.tuberculosis_H37Rv PFFEFLTDLLDGWVAYFAEHPRE--RALHAAATLEVDTDARISVRSVLHR
MSMEG_3452|M.smegmatis_MC2_155 PGDEATRRWMERFIDYATAKSGM--SEALN-----AVIASGADPFADSLS
MLBr_00316|M.leprae_Br4923 PGEALFTYLRSLVLHWGATDRGL--VDALAGAGGIDILG----VAPDAED
TH_2070|M.thermoresistible__bu NPLERFKGLFMASFEAIEHRHAQ--VVIYQDEAKRLSSQPRFAYVEQRNR
Mflv_4630|M.gilvum_PYR-GCK PPEVLAYAPIRGLVSMINNDPRLGRILFVESATEPLLRELRSDMMTGFTD
.
MUL_0910|M.ulcerans_Agy99 RFATAVQTWWRPHAHYGALRPLSPAHSQALWLGPAQELVRAW--------
MMAR_1145|M.marinum_M RFATAVQTWWRPHAHYGALRPLSPAHSQALWLGPAQELVRAW--------
MAB_1552|M.abscessus_ATCC_1997 DFYSQASAWLQPHVEKRRIKPLPPRLCQALWMGPCVEYARLW--------
MAV_1669|M.avium_104 YVEVWVGVLRELNPELAEADARLTAHAVFGLLNSTPHSMKSQ--------
Mvan_4092|M.vanbaalenii_PYR-1 YVEIWVDVLRRRTPGLTETDARLMAHAAFGLLNSTPHGVKP---------
Mb0237|M.bovis_AF2122/97 HYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDP
Rv0232|M.tuberculosis_H37Rv HYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDP
MSMEG_3452|M.smegmatis_MC2_155 MLTEAVGTLLEAGRRDHTLRTDVTAGDVLLFMGGIAYAAQHG--------
MLBr_00316|M.leprae_Br4923 AFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN--------
TH_2070|M.thermoresistible__bu EQRKMWVDVLTQGIEEGYFRSDIDVDLVYRFIRDTTWVSVRWYR------
Mflv_4630|M.gilvum_PYR-GCK LVLREARLHLDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELEFTTDEL
:
MUL_0910|M.ulcerans_Agy99 LLGNLAAPPNAADAAILADAAWLCLRAGPAG--------------
MMAR_1145|M.marinum_M LLGNLAAPPNAADAAILADAAWLCLRAGPAG--------------
MAB_1552|M.abscessus_ATCC_1997 LAR-SADFDMLAAAPVLGQAAWDAVKV------------------
MAV_1669|M.avium_104 DSGRGKPARAARSRAIMRAMTVAALAAGNQCP-------------
Mvan_4092|M.vanbaalenii_PYR-1 --GLNKAAEAS-SRTVLRTMTVAALTSAGRRA-------------
Mb0237|M.bovis_AF2122/97 ILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT
Rv0232|M.tuberculosis_H37Rv ILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT
MSMEG_3452|M.smegmatis_MC2_155 -------TRDQARRLVDLFIDALTKDTRPDT--------------
MLBr_00316|M.leprae_Br4923 --------SALAERVTDVVVDGLRAAR------------------
TH_2070|M.thermoresistible__bu -PGGPLTAEEVGRQYLSIVLGGITAGAN-----------------
Mflv_4630|M.gilvum_PYR-GCK VQHCAGFLGSLGSYVLLQNAVESATTKAKPQS-------------