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MTTQPEPALLGSRNDDGVAAIGDWAAGYIRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVR QGAFMAGTAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLVAAVLMASAVGSAI TADLGSRTMREETDAMEVMGLSVIRRLVVPRFAAAIMIGVALTGVVCFVGFFASYMFNVYFQNGAPGSFV ATFASFATTDDMFLALFKAVMFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSISQLH VMLAPRTGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3794 | yrbE5A | - | 100% (289) | YrbE family protein, YrbE5A |
| M. ulcerans Agy99 | MUL_4921 | yrbE6A | e-105 | 71.76% (262) | integral membrane protein YrbE6A |
| M. ulcerans Agy99 | MUL_4064 | yrbE4A | 7e-46 | 35.48% (279) | membrane protein YrbE4A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0173 | yrbE1A | 8e-45 | 37.25% (255) | integral membrane protein YRBE1A |
| M. gilvum PYR-GCK | Mflv_0012 | - | 1e-131 | 82.70% (289) | hypothetical protein Mflv_0012 |
| M. tuberculosis H37Rv | Rv0167 | yrbE1A | 8e-45 | 37.25% (255) | integral membrane protein YRBE1A |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 2e-43 | 37.87% (235) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_4518c | - | 1e-126 | 82.18% (275) | putative YrbE family protein |
| M. marinum M | MMAR_3862 | yrbE5A | 1e-156 | 98.96% (289) | YrbE family protein, YrbE5A |
| M. avium 104 | MAV_2390 | - | 1e-136 | 89.42% (274) | hypothetical protein MAV_2390 |
| M. smegmatis MC2 155 | MSMEG_1141 | - | 1e-128 | 80.97% (289) | ABC-transporter integral membrane protein |
| M. thermoresistible (build 8) | TH_2930 | - | 1e-132 | 88.32% (274) | PUTATIVE protein of unknown function DUF140 |
| M. vanbaalenii PYR-1 | Mvan_0957 | - | 1e-130 | 85.04% (274) | hypothetical protein Mvan_0957 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3794|M.ulcerans_Agy99 -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG
MMAR_3862|M.marinum_M -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG
MAV_2390|M.avium_104 -----------------------MTATLTTPLDG---VDGVAAIRNWSVG
Mflv_0012|M.gilvum_PYR-GCK MRLPGPRTRCGRRHRRSECTAAERTSGMTTADQPVRRDDSVHAVQDWVGG
TH_2930|M.thermoresistible__bu ----------------------------------MTRSDGVEVIGEWAGG
MSMEG_1141|M.smegmatis_MC2_155 -----------------------MTTSPDRVSDGGAPERGTDAIEKWATG
Mvan_0957|M.vanbaalenii_PYR-1 -------------------------MSSDTKGEG------VGVITDWAGG
MAB_4518c|M.abscessus_ATCC_199 ---------------------------MTTPGGRVATEDGAAAIQDWATG
Mb0173|M.bovis_AF2122/97 ---------------------------------------MTTST--TLGG
Rv0167|M.tuberculosis_H37Rv ---------------------------------------MTTST--TLGG
MLBr_02587|M.leprae_Br4923 ---------------------------------------MTTETRSSLVE
.
MUL_3794|M.ulcerans_Agy99 YIRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG
MMAR_3862|M.marinum_M YVRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG
MAV_2390|M.avium_104 YVKRHPVASLTTVGEQFVLGVRTIQYFFYDLITGRFQWQEFVRQGAFMAG
Mflv_0012|M.gilvum_PYR-GCK YVRRHPLASLATVGDQFVLGVRTLQWFFVDLFTGRFQFQEFVRQGAFMAG
TH_2930|M.thermoresistible__bu YIRRHPLAALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFVRQAAFMAG
MSMEG_1141|M.smegmatis_MC2_155 YVRRHPIASLTTVGDQFVLGVRTVQYLFTELFTGRFQWQEFIRQGAFMAS
Mvan_0957|M.vanbaalenii_PYR-1 YVKRHPLASLTTVGDQFVLGVRTVQYFLLDLFSGRFQWQEFIRQGAFMAG
MAB_4518c|M.abscessus_ATCC_199 YVKRHPLESLSTVGEQFMLGVRTLQWFFVDLFTGQFQWQEFVRQGAFQAA
Mb0173|M.bovis_AF2122/97 YVRDQLQTPLTLVGGFFRMCVLTGK----ALFRWPFQWREFILQCWFIMR
Rv0167|M.tuberculosis_H37Rv YVRDQLQTPLTLVGGFFRMCVLTGK----ALFRWPFQWREFILQCWFIMR
MLBr_02587|M.leprae_Br4923 YAHTKLQTPLVLVGGFFRMLVLTGK----ALFRRPFQWREFILQCWFIMR
* : : .* ** * : * * : *. **: **: * *
MUL_3794|M.ulcerans_Agy99 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
MMAR_3862|M.marinum_M TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
MAV_2390|M.avium_104 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
Mflv_0012|M.gilvum_PYR-GCK TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
TH_2930|M.thermoresistible__bu TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
MSMEG_1141|M.smegmatis_MC2_155 TAVVPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
Mvan_0957|M.vanbaalenii_PYR-1 TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
MAB_4518c|M.abscessus_ATCC_199 TAVMPVILVTLPIGVTLSIQFALLAGQVGATSLAGAASGIAIIRQAASLV
Mb0173|M.bovis_AF2122/97 VGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLGPLT
Rv0167|M.tuberculosis_H37Rv VGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLGPLT
MLBr_02587|M.leprae_Br4923 VAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGAVTQLGPLT
...:*.::*::*: * * : : :* .*..*:.::*:.:.:. : * ..*.
MUL_3794|M.ulcerans_Agy99 AAVLMASAVGSAITADLGSRTMREETDAMEVMGLSVIRRLVVPRFAAAIM
MMAR_3862|M.marinum_M AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MAV_2390|M.avium_104 AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVVRRLVVPRFAAAVM
Mflv_0012|M.gilvum_PYR-GCK AAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVVPRFAAAIM
TH_2930|M.thermoresistible__bu AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MSMEG_1141|M.smegmatis_MC2_155 AAVLMAAAVGSAITADLGSRKMREETDAMEVMGVSVIKRLVVPRFAAAIM
Mvan_0957|M.vanbaalenii_PYR-1 AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MAB_4518c|M.abscessus_ATCC_199 AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
Mb0173|M.bovis_AF2122/97 TVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASML
Rv0167|M.tuberculosis_H37Rv TVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASML
MLBr_02587|M.leprae_Br4923 TVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLAATL
:.:::*.* .::* ****:*.:*** *****:*:. ::******. *: :
MUL_3794|M.ulcerans_Agy99 IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF
MMAR_3862|M.marinum_M IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF
MAV_2390|M.avium_104 IGVALTGVVCFAGFFASYMFNVYFQNGAPGSFVSTSASFATTGDMILALL
Mflv_0012|M.gilvum_PYR-GCK IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV
TH_2930|M.thermoresistible__bu IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFTTTGDMLVALI
MSMEG_1141|M.smegmatis_MC2_155 IGVALTGVVCFVGFIASFLFNVYFQDGAPGSFVATFASFATTGDMIVALI
Mvan_0957|M.vanbaalenii_PYR-1 IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV
MAB_4518c|M.abscessus_ATCC_199 IAVALTAVVCFVGFLGAYLFNVYWQGGAPGSFVSTFASFATPDDMVLAVL
Mb0173|M.bovis_AF2122/97 VATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATI
Rv0167|M.tuberculosis_H37Rv VATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATI
MLBr_02587|M.leprae_Br4923 VATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGLPEVVIATV
:.. *..:* .*:...::*.** *. : *::::* : :: ::.:* .
MUL_3794|M.ulcerans_Agy99 KAVMFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS
MMAR_3862|M.marinum_M KAVIFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS
MAV_2390|M.avium_104 KAIVFGAIVAIVSSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVNVAIS
Mflv_0012|M.gilvum_PYR-GCK KAVIFGAIVAIVSCQKGLSTQGGPTGVANSVNAAVVESILVLMVVNVAIS
TH_2930|M.thermoresistible__bu KAVVFGAIVAVVSCQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVGIS
MSMEG_1141|M.smegmatis_MC2_155 KAVIFGAIVAVVSCQKGLSTVGGPTGVANSVNAAVVESILLLMVVNVAIS
Mvan_0957|M.vanbaalenii_PYR-1 KAVIFGAIVAVVSCQKGLATQGGPTGVANSVNAAVVESILLLMVVNVAIS
MAB_4518c|M.abscessus_ATCC_199 KAIIYGAIVAVVSCQKGLSTKGGPIGVANSVNAAVVESILLLMVVNVAIS
Mb0173|M.bovis_AF2122/97 KAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILT
Rv0167|M.tuberculosis_H37Rv KAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILT
MLBr_02587|M.leprae_Br4923 KAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVALYAVNVVLT
** :* *..:*.. :** . **. *:. :** :** .:: * *** ::
MUL_3794|M.ulcerans_Agy99 QLHVMLAPRTGL
MMAR_3862|M.marinum_M QLHVMLAPRTGL
MAV_2390|M.avium_104 QLYIMLSPRTGL
Mflv_0012|M.gilvum_PYR-GCK QLYILMFPRVGL
TH_2930|M.thermoresistible__bu QLYIMLFPRVGL
MSMEG_1141|M.smegmatis_MC2_155 QLYIMLFPRVGL
Mvan_0957|M.vanbaalenii_PYR-1 QLYIMMFPRVGL
MAB_4518c|M.abscessus_ATCC_199 QLYIMMFPRTGL
Mb0173|M.bovis_AF2122/97 TIGVRFG--TGR
Rv0167|M.tuberculosis_H37Rv TIGVRFG--TGR
MLBr_02587|M.leprae_Br4923 TIGVRFG--TGH
: : : .*