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M. ulcerans Agy99 MUL_4921 (yrbE6A)

annotation: integral membrane protein YrbE6A
coordinates: 5452843 - 5453688
length: 281

ATTFVNDRLIGLRRLSVTYLRQHPAASLATAGEQIVLGVAALRYLAIDLVTGRFPWTECIRQASFMAATA
IMPTILVALPIGATLSIQFAMLAGQVGATSLAGAASGLTVVRQAASLVAAILLAAAVGSAITADLGVRTM
REETDAMEMMGVSVVRNLVVPRLLAAMVIGVALCGVVCFVGFLASYLFNVYVQGGSAGSFLATFSAFATT
GDMILALLKAAVYGFIVTVVACQKGLSTRGGPAGVANSVNAAVVEAVLLLMIVNVVVSELYTVLFPRTGL
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4921yrbE6A-100% (281)integral membrane protein YrbE6A
M. ulcerans Agy99MUL_3794yrbE5Ae-10571.76% (262) YrbE family protein, YrbE5A
M. ulcerans Agy99MUL_3916yrbE3A_19e-4439.19% (222) integral membrane protein YrbE3A_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0173yrbE1A6e-4438.71% (217) integral membrane protein YRBE1A
M. gilvum PYR-GCKMflv_0012-1e-10873.28% (262) hypothetical protein Mflv_0012
M. tuberculosis H37RvRv0167yrbE1A7e-4438.71% (217) integral membrane protein YRBE1A
M. leprae Br4923MLBr_02587yrbE1A2e-4339.63% (217) hypothetical protein MLBr_02587
M. abscessus ATCC 19977MAB_1693-1e-10976.34% (262) hypothetical protein MAB_1693
M. marinum MMMAR_0175yrbE6A1e-15099.64% (281) integral membrane protein YrbE6A
M. avium 104MAV_2390-1e-10871.53% (274) hypothetical protein MAV_2390
M. smegmatis MC2 155MSMEG_1141-1e-10771.38% (269) ABC-transporter integral membrane protein
M. thermoresistible (build 8)TH_2930-1e-11075.57% (262) PUTATIVE protein of unknown function DUF140
M. vanbaalenii PYR-1Mvan_0957-1e-10973.66% (262) hypothetical protein Mvan_0957

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4921|M.ulcerans_Agy99           ---------------------------MAT--------TFVNDRLIGLRR
MMAR_0175|M.marinum_M               ---------------------------MAT--------TFVNDRLIGLRR
MAB_1693|M.abscessus_ATCC_1997      ---------------------------MTTRDQLVRVGGQMPKRIRTLGA
Mflv_0012|M.gilvum_PYR-GCK          MRLPGPRTRCGRRHRRSECTAAERTSGMTTADQPV----RRDDSVHAVQD
Mvan_0957|M.vanbaalenii_PYR-1       ---------------------------MSSDTK--------GEGVGVITD
TH_2930|M.thermoresistible__bu      ---------------------------MT-----------RSDGVEVIGE
MSMEG_1141|M.smegmatis_MC2_155      --------------------MTTSPDRVSDGGAP-------ERGTDAIEK
MAV_2390|M.avium_104                -----------------------MTATLTTPLDG-------VDGVAAIRN
Mb0173|M.bovis_AF2122/97            -------------------------------------------MTTST--
Rv0167|M.tuberculosis_H37Rv         -------------------------------------------MTTST--
MLBr_02587|M.leprae_Br4923          -------------------------------------------MTTETRS
                                                                                      

MUL_4921|M.ulcerans_Agy99           LSVTYLRQHPAASLATAGEQIVLGVAALRYLAIDLVTGRFPWTECIRQAS
MMAR_0175|M.marinum_M               LSVTYLRQHPAASLATAGEQIVLGVAALRYLAIDLVTGRFPWTECIRQAS
MAB_1693|M.abscessus_ATCC_1997      CGAGYVRHHPIAALTTVGEQFVLGVHTLRYFVADLVMGRFQWAEFVRQAA
Mflv_0012|M.gilvum_PYR-GCK          WVGGYVRRHPLASLATVGDQFVLGVRTLQWFFVDLFTGRFQFQEFVRQGA
Mvan_0957|M.vanbaalenii_PYR-1       WAGGYVKRHPLASLTTVGDQFVLGVRTVQYFLLDLFSGRFQWQEFIRQGA
TH_2930|M.thermoresistible__bu      WAGGYIRRHPLAALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFVRQAA
MSMEG_1141|M.smegmatis_MC2_155      WATGYVRRHPIASLTTVGDQFVLGVRTVQYLFTELFTGRFQWQEFIRQGA
MAV_2390|M.avium_104                WSVGYVKRHPVASLTTVGEQFVLGVRTIQYFFYDLITGRFQWQEFVRQGA
Mb0173|M.bovis_AF2122/97            TLGGYVRDQLQTPLTLVGGFFRMCVLTG----KALFRWPFQWREFILQCW
Rv0167|M.tuberculosis_H37Rv         TLGGYVRDQLQTPLTLVGGFFRMCVLTG----KALFRWPFQWREFILQCW
MLBr_02587|M.leprae_Br4923          SLVEYAHTKLQTPLVLVGGFFRMLVLTG----KALFRRPFQWREFILQCW
                                        * : :  :.*  .*  : : * :       *.   * : * : *  

MUL_4921|M.ulcerans_Agy99           FMAATAIMPTILVALPIGATLSIQFAMLAGQVGATSLAGAASGLTVVRQA
MMAR_0175|M.marinum_M               FMAATAIMPTILVALPIGATLSIQFAMLAGQVGATSLAGAASGLTVVRQA
MAB_1693|M.abscessus_ATCC_1997      FMAGTAVMPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVVRQA
Mflv_0012|M.gilvum_PYR-GCK          FMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQA
Mvan_0957|M.vanbaalenii_PYR-1       FMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQA
TH_2930|M.thermoresistible__bu      FMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQA
MSMEG_1141|M.smegmatis_MC2_155      FMASTAVVPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQA
MAV_2390|M.avium_104                FMAGTAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQG
Mb0173|M.bovis_AF2122/97            FIMRVGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQL
Rv0167|M.tuberculosis_H37Rv         FIMRVGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQL
MLBr_02587|M.leprae_Br4923          FIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGAVTQL
                                    *:  ...:**::*::*: . * : : :* .*..*:.::*:.:.: .: * 

MUL_4921|M.ulcerans_Agy99           ASLVAAILLAAAVGSAITADLGVRTMREETDAMEMMGVSVVRNLVVPRLL
MMAR_0175|M.marinum_M               ASLVAAILLAAAVGSAITADLGVRTMREETDAMEVMGVSVVRNLVVPRLL
MAB_1693|M.abscessus_ATCC_1997      ASLVAAMLLASAVGSAMTADLGCRTMREETAAMEVMGVSVVRRLVVPRFA
Mflv_0012|M.gilvum_PYR-GCK          ASLTAAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVVPRFA
Mvan_0957|M.vanbaalenii_PYR-1       ASLTAAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFA
TH_2930|M.thermoresistible__bu      ASLTAAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFA
MSMEG_1141|M.smegmatis_MC2_155      ASLTAAVLMAAAVGSAITADLGSRKMREETDAMEVMGVSVIKRLVVPRFA
MAV_2390|M.avium_104                ASLVAAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVVRRLVVPRFA
Mb0173|M.bovis_AF2122/97            GPLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVL
Rv0167|M.tuberculosis_H37Rv         GPLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVL
MLBr_02587|M.leprae_Br4923          GPLTTVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVVPRVL
                                    ..*.:.:::*.* .::: **** *.:***  ***::*:. ::.*****. 

MUL_4921|M.ulcerans_Agy99           AAMVIGVALCGVVCFVGFLASYLFNVYVQGGSAGSFLATFSAFATTGDMI
MMAR_0175|M.marinum_M               AAMVIGVALCGVVCFVGFLASYLFNVYVQGGSAGSFLATFSAFATTGDMI
MAB_1693|M.abscessus_ATCC_1997      AAIVIGIALTGVVCFVGFLASYLFNVFVQGGAPGSFVSTFASFATPADLL
Mflv_0012|M.gilvum_PYR-GCK          AAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMI
Mvan_0957|M.vanbaalenii_PYR-1       AAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMI
TH_2930|M.thermoresistible__bu      AAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFTTTGDML
MSMEG_1141|M.smegmatis_MC2_155      AAIMIGVALTGVVCFVGFIASFLFNVYFQDGAPGSFVATFASFATTGDMI
MAV_2390|M.avium_104                AAVMIGVALTGVVCFAGFFASYMFNVYFQNGAPGSFVSTSASFATTGDMI
Mb0173|M.bovis_AF2122/97            ASMLVATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVV
Rv0167|M.tuberculosis_H37Rv         ASMLVATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVV
MLBr_02587|M.leprae_Br4923          AATLVATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGLPEVV
                                    *: ::.  * *:*  .*:...::*.*:.*. : *::::* : ::   :::

MUL_4921|M.ulcerans_Agy99           LALLKAAVYGFIVTVVACQKGLSTRGGPAGVANSVNAAVVEAVLLLMIVN
MMAR_0175|M.marinum_M               LALLKAAVYGFIVTVVACQKGLSTRGGPAGVANSVNAAVVEAVLLLMIVN
MAB_1693|M.abscessus_ATCC_1997      LALFKAAAYGAIVAVIACQKGLAAHGGPTGVANSVNAAVVESVLLLMIVN
Mflv_0012|M.gilvum_PYR-GCK          VALVKAVIFGAIVAIVSCQKGLSTQGGPTGVANSVNAAVVESILVLMVVN
Mvan_0957|M.vanbaalenii_PYR-1       VALVKAVIFGAIVAVVSCQKGLATQGGPTGVANSVNAAVVESILLLMVVN
TH_2930|M.thermoresistible__bu      VALIKAVVFGAIVAVVSCQKGLSTKGGPTGVANSVNAAVVESILVLMIVN
MSMEG_1141|M.smegmatis_MC2_155      VALIKAVIFGAIVAVVSCQKGLSTVGGPTGVANSVNAAVVESILLLMVVN
MAV_2390|M.avium_104                LALLKAIVFGAIVAIVSSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVN
Mb0173|M.bovis_AF2122/97            IATIKAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVN
Rv0167|M.tuberculosis_H37Rv         IATIKAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVN
MLBr_02587|M.leprae_Br4923          IATVKAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVALYAVN
                                    :* .**  :* *. ::.. :** . **. *:. :** :** .:: *  **

MUL_4921|M.ulcerans_Agy99           VVVSELYTVLFPRTGL
MMAR_0175|M.marinum_M               VVVSELYTVLFPRTGL
MAB_1693|M.abscessus_ATCC_1997      VVVSQVYTMLFPRAVL
Mflv_0012|M.gilvum_PYR-GCK          VAISQLYILMFPRVGL
Mvan_0957|M.vanbaalenii_PYR-1       VAISQLYIMMFPRVGL
TH_2930|M.thermoresistible__bu      VGISQLYIMLFPRVGL
MSMEG_1141|M.smegmatis_MC2_155      VAISQLYIMLFPRVGL
MAV_2390|M.avium_104                VAISQLYIMLSPRTGL
Mb0173|M.bovis_AF2122/97            VILTTIGVRFGTGR--
Rv0167|M.tuberculosis_H37Rv         VILTTIGVRFGTGR--
MLBr_02587|M.leprae_Br4923          VVLTTIGVRFGTGH--
                                    * :: :   : .