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RLPGPRTRCGRRHRRSECTAAERTSGMTTADQPVRRDDSVHAVQDWVGGYVRRHPLASLATVGDQFVLGV RTLQWFFVDLFTGRFQFQEFVRQGAFMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLA VIRQAASLTAAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVVPRFAAAIMIGVALTGVVCF VGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALVKAVIFGAIVAIVSCQKGLSTQGGPTGVANSV NAAVVESILVLMVVNVAISQLYILMFPRVGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0012 | - | - | 100% (312) | hypothetical protein Mflv_0012 |
| M. gilvum PYR-GCK | Mflv_1554 | - | 1e-46 | 37.93% (232) | hypothetical protein Mflv_1554 |
| M. gilvum PYR-GCK | Mflv_2099 | - | 2e-45 | 37.89% (227) | hypothetical protein Mflv_2099 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0173 | yrbE1A | 2e-46 | 37.25% (255) | integral membrane protein YRBE1A |
| M. tuberculosis H37Rv | Rv0167 | yrbE1A | 2e-46 | 37.25% (255) | integral membrane protein YRBE1A |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 4e-45 | 40.09% (222) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_1012c | - | 1e-131 | 82.11% (285) | putative YrbE family protein |
| M. marinum M | MMAR_3862 | yrbE5A | 1e-132 | 83.74% (289) | YrbE family protein, YrbE5A |
| M. avium 104 | MAV_2390 | - | 1e-128 | 81.98% (283) | hypothetical protein MAV_2390 |
| M. smegmatis MC2 155 | MSMEG_1141 | - | 1e-134 | 90.00% (270) | ABC-transporter integral membrane protein |
| M. thermoresistible (build 8) | TH_2930 | - | 1e-137 | 89.86% (276) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_3794 | yrbE5A | 1e-131 | 82.70% (289) | YrbE family protein, YrbE5A |
| M. vanbaalenii PYR-1 | Mvan_0957 | - | 1e-138 | 91.67% (276) | hypothetical protein Mvan_0957 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0012|M.gilvum_PYR-GCK MRLPGPRTRCGRRHRRSECTAAERTSGMTTADQPVRRDDSVHAVQDWVGG
TH_2930|M.thermoresistible__bu ----------------------------------MTRSDGVEVIGEWAGG
MSMEG_1141|M.smegmatis_MC2_155 -----------------------MTTSPDRVSDGGAPERGTDAIEKWATG
Mvan_0957|M.vanbaalenii_PYR-1 -------------------------MSSDTKGEG------VGVITDWAGG
MMAR_3862|M.marinum_M -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG
MUL_3794|M.ulcerans_Agy99 -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG
MAV_2390|M.avium_104 -----------------------MTATLTTPLDG---VDGVAAIRNWSVG
MAB_1012c|M.abscessus_ATCC_199 -----------------------MTTQDERRATN----DGVAAIQDWTTG
Mb0173|M.bovis_AF2122/97 -----------------------MTTST------------------TLGG
Rv0167|M.tuberculosis_H37Rv -----------------------MTTST------------------TLGG
MLBr_02587|M.leprae_Br4923 -----------------------MTTETR----------------SSLVE
Mflv_0012|M.gilvum_PYR-GCK YVRRHPLASLATVGDQFVLGVRTLQWFFVDLFTGRFQFQEFVRQGAFMAG
TH_2930|M.thermoresistible__bu YIRRHPLAALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFVRQAAFMAG
MSMEG_1141|M.smegmatis_MC2_155 YVRRHPIASLTTVGDQFVLGVRTVQYLFTELFTGRFQWQEFIRQGAFMAS
Mvan_0957|M.vanbaalenii_PYR-1 YVKRHPLASLTTVGDQFVLGVRTVQYFLLDLFSGRFQWQEFIRQGAFMAG
MMAR_3862|M.marinum_M YVRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG
MUL_3794|M.ulcerans_Agy99 YIRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG
MAV_2390|M.avium_104 YVKRHPVASLTTVGEQFVLGVRTIQYFFYDLITGRFQWQEFVRQGAFMAG
MAB_1012c|M.abscessus_ATCC_199 YVKRHPLESLKTVGEQFMLGVRTIQWFFVDLFTGNFQWQEFVRQGAFQAG
Mb0173|M.bovis_AF2122/97 YVRDQLQTPLTLVGGFFRMCVLTGK----ALFRWPFQWREFILQCWFIMR
Rv0167|M.tuberculosis_H37Rv YVRDQLQTPLTLVGGFFRMCVLTGK----ALFRWPFQWREFILQCWFIMR
MLBr_02587|M.leprae_Br4923 YAHTKLQTPLVLVGGFFRMLVLTGK----ALFRRPFQWREFILQCWFIMR
* : : .* ** * : * * : *. **: **: * *
Mflv_0012|M.gilvum_PYR-GCK TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
TH_2930|M.thermoresistible__bu TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
MSMEG_1141|M.smegmatis_MC2_155 TAVVPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
Mvan_0957|M.vanbaalenii_PYR-1 TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT
MMAR_3862|M.marinum_M TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
MUL_3794|M.ulcerans_Agy99 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
MAV_2390|M.avium_104 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV
MAB_1012c|M.abscessus_ATCC_199 TAVVPVILVTLPIGVTLSIQFALLAGQVGATSLAGAASGIAIIRQAASLV
Mb0173|M.bovis_AF2122/97 VGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLGPLT
Rv0167|M.tuberculosis_H37Rv VGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLGPLT
MLBr_02587|M.leprae_Br4923 VAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGAVTQLGPLT
...:*.::*::*: * * : : :* .*..*:.::*:.:.:. : * ..*.
Mflv_0012|M.gilvum_PYR-GCK AAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVVPRFAAAIM
TH_2930|M.thermoresistible__bu AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MSMEG_1141|M.smegmatis_MC2_155 AAVLMAAAVGSAITADLGSRKMREETDAMEVMGVSVIKRLVVPRFAAAIM
Mvan_0957|M.vanbaalenii_PYR-1 AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MMAR_3862|M.marinum_M AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
MUL_3794|M.ulcerans_Agy99 AAVLMASAVGSAITADLGSRTMREETDAMEVMGLSVIRRLVVPRFAAAIM
MAV_2390|M.avium_104 AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVVRRLVVPRFAAAVM
MAB_1012c|M.abscessus_ATCC_199 AALLMSAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM
Mb0173|M.bovis_AF2122/97 TVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASML
Rv0167|M.tuberculosis_H37Rv TVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASML
MLBr_02587|M.leprae_Br4923 TVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLAATL
:.::::.* .::* ****:*.:*** *****:*:. ::******. *: :
Mflv_0012|M.gilvum_PYR-GCK IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV
TH_2930|M.thermoresistible__bu IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFTTTGDMLVALI
MSMEG_1141|M.smegmatis_MC2_155 IGVALTGVVCFVGFIASFLFNVYFQDGAPGSFVATFASFATTGDMIVALI
Mvan_0957|M.vanbaalenii_PYR-1 IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV
MMAR_3862|M.marinum_M IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF
MUL_3794|M.ulcerans_Agy99 IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF
MAV_2390|M.avium_104 IGVALTGVVCFAGFFASYMFNVYFQNGAPGSFVSTSASFATTGDMILALL
MAB_1012c|M.abscessus_ATCC_199 IGIALTGVVCFVGFLGAYLFNVYWQNGAPGSFVTTFSAFATPGDMILALI
Mb0173|M.bovis_AF2122/97 VATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATI
Rv0167|M.tuberculosis_H37Rv VATLLNGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATI
MLBr_02587|M.leprae_Br4923 VATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGLPEVVIATV
:. *.*:* .*:...::*.** *: : *::::* : :: ::.:* .
Mflv_0012|M.gilvum_PYR-GCK KAVIFGAIVAIVSCQKGLSTQGGPTGVANSVNAAVVESILVLMVVNVAIS
TH_2930|M.thermoresistible__bu KAVVFGAIVAVVSCQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVGIS
MSMEG_1141|M.smegmatis_MC2_155 KAVIFGAIVAVVSCQKGLSTVGGPTGVANSVNAAVVESILLLMVVNVAIS
Mvan_0957|M.vanbaalenii_PYR-1 KAVIFGAIVAVVSCQKGLATQGGPTGVANSVNAAVVESILLLMVVNVAIS
MMAR_3862|M.marinum_M KAVIFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS
MUL_3794|M.ulcerans_Agy99 KAVMFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS
MAV_2390|M.avium_104 KAIVFGAIVAIVSSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVNVAIS
MAB_1012c|M.abscessus_ATCC_199 KAVIYGAIVAVVACQKGLSTKGGPIGVANSVNAAVVESILLLMTVNLAIS
Mb0173|M.bovis_AF2122/97 KAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILT
Rv0167|M.tuberculosis_H37Rv KAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILT
MLBr_02587|M.leprae_Br4923 KAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVALYAVNVVLT
** :* *..:*.. :** . **. *:. :** :** .:: * **: ::
Mflv_0012|M.gilvum_PYR-GCK QLYILMFPRVGL
TH_2930|M.thermoresistible__bu QLYIMLFPRVGL
MSMEG_1141|M.smegmatis_MC2_155 QLYIMLFPRVGL
Mvan_0957|M.vanbaalenii_PYR-1 QLYIMMFPRVGL
MMAR_3862|M.marinum_M QLHVMLAPRTGL
MUL_3794|M.ulcerans_Agy99 QLHVMLAPRTGL
MAV_2390|M.avium_104 QLYIMLSPRTGL
MAB_1012c|M.abscessus_ATCC_199 QLYIMMFPRTGL
Mb0173|M.bovis_AF2122/97 TIGVRFG--TGR
Rv0167|M.tuberculosis_H37Rv TIGVRFG--TGR
MLBr_02587|M.leprae_Br4923 TIGVRFG--TGH
: : : .*