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ELMMPTDASFLFTESREHPMHVAGLQLFDPPDAAGPGFVDEIYRCLAANREGQPAFRKHPATLLGGITNL GWQYDNEIDTDYHVRRSVLPYPGRVRELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHAL LDGASALMLLQRALSDDPRDTEVRAPWNLPPQPDHAVGSSRLGSLANTAGSLMALGPSTVSLIRAALVEQ QLTLPFGAPRTLFNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQYLLEQNALPDAP LVALVPVSLRSQTDDSGDTMVGTVLCGLATDTTDPAKRLEMISQSMRRNKKAFSELSPLQAKALWAFNMA PLTLTAVPGFVPWTKPSFNVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSNAGTLEFGLV GCRRSVPHLQRLLLHLETSLYGLEQAVGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1193 | - | - | 100% (450) | hypothetical protein MUL_1193 |
| M. ulcerans Agy99 | MUL_2057 | - | e-153 | 60.22% (455) | hypothetical protein MUL_2057 |
| M. ulcerans Agy99 | MUL_4351 | - | e-146 | 58.35% (449) | hypothetical protein MUL_4351 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3761c | - | 1e-172 | 65.86% (454) | hypothetical protein Mb3761c |
| M. gilvum PYR-GCK | Mflv_1058 | - | 1e-76 | 37.74% (469) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3734c | - | 1e-172 | 65.86% (454) | hypothetical protein Rv3734c |
| M. leprae Br4923 | MLBr_01244 | - | 5e-23 | 27.60% (366) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 1e-121 | 48.26% (460) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_0529 | - | 0.0 | 99.33% (450) | hypothetical protein MMAR_0529 |
| M. avium 104 | MAV_0355 | - | 1e-176 | 67.56% (450) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 1e-165 | 63.58% (453) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 1e-157 | 62.39% (452) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 5e-77 | 38.21% (458) | hypothetical protein Mvan_5773 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
Mvan_5773|M.vanbaalenii_PYR-1 -------------M----FIYGETSSSKMHVAGLLPFTPP-ADAPRDYLR
MUL_1193|M.ulcerans_Agy99 ----MELMMPTDAS----FLFTESREHPMHVAGLQLFDPP-DAAGPGFVD
MMAR_0529|M.marinum_M -MTSMELMMPTDAS----FLFTESREHPMHVAGLQLFDPP-DAAGPGFVD
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
Mb3761c|M.bovis_AF2122/97 ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
Rv3734c|M.tuberculosis_H37Rv ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELL--DTTPDWN-
:: . .*: : :
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
Mvan_5773|M.vanbaalenii_PYR-1 RMVDDARRQEVMPPWNRKLAYPRLQFSPLHTWVTDTEFDFDYHVRRSALA
MUL_1193|M.ulcerans_Agy99 EIYRCLAANREGQPAFRKHPATLLGGITNLGWQYDNEIDTDYHVRRSVLP
MMAR_0529|M.marinum_M EIYRCLAANREGQPAFRKHPATLLGGITNLGWQYDNEIDTDYHVRRSVLP
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
Mb3761c|M.bovis_AF2122/97 EFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALP
Rv3734c|M.tuberculosis_H37Rv EFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALP
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
MLBr_01244|M.leprae_Br4923 RFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
: *: * * :.: ::*:** :.
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
Mvan_5773|M.vanbaalenii_PYR-1 SPGDERELGILVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
MUL_1193|M.ulcerans_Agy99 YPGRVRELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHAL
MMAR_0529|M.marinum_M YPGRVSELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
Mb3761c|M.bovis_AF2122/97 SPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHAL
Rv3734c|M.tuberculosis_H37Rv SPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHAL
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
* :: :.. : :* * * :::*: ** *: :. *::
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRSRRDPGAAESSNPLTA
Mvan_5773|M.vanbaalenii_PYR-1 VDGYTAMRMLGRSLSTDPETRDARMFFNVPIPKRSRPTGAGAQSSNPVTA
MUL_1193|M.ulcerans_Agy99 LDGASALMLLQRALSDDPRDTEVRAPWNLPPQPDHAVGS----------S
MMAR_0529|M.marinum_M LDGASALMLLQRALSDDPRDTEVRAPWNLPPQPDHAVGS----------S
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSEDPSDTTVRVPWNLPRR-ESSRRAGSS-------S
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTDPGDD-ARVPWNLPPP-RRNP-AGPV-------S
Mb3761c|M.bovis_AF2122/97 IDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPSDGS-------S
Rv3734c|M.tuberculosis_H37Rv IDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPSDGS-------S
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSDPDDPEIRAPWTLPKRSRKAGPS----------S
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDDPDARDCQAVWAPAKRRAKSSIVSTTNTSA--ID
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVA
** : . . :
Mflv_1058|M.gilvum_PYR-GCK TLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSVSAPHSI
Mvan_5773|M.vanbaalenii_PYR-1 TLRALGAVGSTVSDGVGSAVDLASALVNTQIRRDGDFGRISGSASAPHSI
MUL_1193|M.ulcerans_Agy99 RLGSLANTAGSLMALGPSTVSLIRAALVEQQ--------LTLPFGAPRTL
MMAR_0529|M.marinum_M RLGSLANTAGSLMALGPSTVSLIRAALVEQQ--------LTLPFGAPRTL
MSMEG_6322|M.smegmatis_MC2_155 LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPFGAPRTM
TH_2030|M.thermoresistible__bu RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPFGAPRTM
Mb3761c|M.bovis_AF2122/97 LLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAPHSM
Rv3734c|M.tuberculosis_H37Rv LLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAPHSM
MAV_0355|M.avium_104 RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPFGAPRTM
MAB_4544c|M.abscessus_ATCC_199 LVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPLSAPHTM
MLBr_01244|M.leprae_Br4923 LAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPSPL
: : : : . * .:
Mflv_1058|M.gilvum_PYR-GCK LNARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGGLRKFLSD
Mvan_5773|M.vanbaalenii_PYR-1 LNARISRNRRFATQQYEFDRLKKLSSQHGATINDVALAIIGGGLRKFLAD
MUL_1193|M.ulcerans_Agy99 FNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQYLLE
MMAR_0529|M.marinum_M FNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQYLLE
MSMEG_6322|M.smegmatis_MC2_155 FNVKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRAYLAE
TH_2030|M.thermoresistible__bu FNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQYLLE
Mb3761c|M.bovis_AF2122/97 FNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIE
Rv3734c|M.tuberculosis_H37Rv FNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIE
MAV_0355|M.avium_104 LNVKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRYYLLE
MAB_4544c|M.abscessus_ATCC_199 LNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYLEE
MLBr_01244|M.leprae_Br4923 LRQRS-LATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYH-E
:. * : : :: . ::** ** *.** : :
Mflv_1058|M.gilvum_PYR-GCK FDKLPDRSLIAFLPVNVRPKGD-EGGGNAVGAILAPMGTDIEDPVERLDT
Mvan_5773|M.vanbaalenii_PYR-1 LGELPDRSLIAFLPVNVRPKGD-EGGGNAVGAILAPMGTDIEDPVERLAV
MUL_1193|M.ulcerans_Agy99 QNALPDAPLVALVPVSLRSQTD-DSGDTMVGTVLCGLATDTTDPAKRLEM
MMAR_0529|M.marinum_M QNALPDAPLVALVPVSLRSQTD-DSGGTMVGTVLCGLATDTTDPAKRLEM
MSMEG_6322|M.smegmatis_MC2_155 QDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVEDPADRLAV
TH_2030|M.thermoresistible__bu HDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDDPAERLDR
Mb3761c|M.bovis_AF2122/97 RNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCNLATHVDDPAQRIQT
Rv3734c|M.tuberculosis_H37Rv RNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCNLATHVDDPAQRIQT
MAV_0355|M.avium_104 QNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDDPAQRLLT
MAB_4544c|M.abscessus_ATCC_199 QNALPDKPLVAMCPVSIRAEGDQNAGNSIT-ALLANLATDKPDPLERFSA
MLBr_01244|M.leprae_Br4923 ALGVSISTLPMAVPVNVRTEADVVGSNRFVGVTLAAPLG-TNDPAARMQK
:. .* **.:*. : ... . *. ** *:
Mflv_1058|M.gilvum_PYR-GCK ITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQPPWPYTF
Mvan_5773|M.vanbaalenii_PYR-1 ITAATRASKAQLQSMSPAAIIAYSAALLAPAGGQIAGALTGVNPPWPHTF
MUL_1193|M.ulcerans_Agy99 ISQSMRRNKKAFSELSPLQAKALWAFNMAPL--TLT-AVPGFVPWTKPSF
MMAR_0529|M.marinum_M ISQSMRRNKKAFSELSPLQAKALWAFNMAPL--TLT-AVPGFVPWTKPSF
MSMEG_6322|M.smegmatis_MC2_155 IRRSITDNKRVFSELPRLQALALSALLIAPL--GLTTAFPGFVDATAPPF
TH_2030|M.thermoresistible__bu ISSSMRSNKRVFSQLPRVQAMALSAAMIAPL--GLG-AVPGVVSSAPPPF
Mb3761c|M.bovis_AF2122/97 ISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFLSAVPPPF
Rv3734c|M.tuberculosis_H37Rv ISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFLSAVPPPF
MAV_0355|M.avium_104 ISESMRSNKKVFSQLPRFQALALSAANLSSL--ALA-AVPGWVSATSPPF
MAB_4544c|M.abscessus_ATCC_199 IRDSVQAAKSVLSEMTPLQRMLVGALNGAPV--LTG-AVPGLVDRTAPAF
MLBr_01244|M.leprae_Br4923 IRSQMTQRR----DEPAMNIIGS----LAPLMTVLPASVLDFIVDSVASS
* : . . :. .. . .
Mflv_1058|M.gilvum_PYR-GCK NLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSYADTMNLG
Mvan_5773|M.vanbaalenii_PYR-1 NLCVSNVPGPREPLYFNGSRLEATFPVSIPIHGMALNITLQSYADTMNLG
MUL_1193|M.ulcerans_Agy99 NVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSNAGTLEFG
MMAR_0529|M.marinum_M NVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSNAGTLEFG
MSMEG_6322|M.smegmatis_MC2_155 NLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSNAHNLDFG
TH_2030|M.thermoresistible__bu NLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTNADNLDFG
Mb3761c|M.bovis_AF2122/97 NIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDFG
Rv3734c|M.tuberculosis_H37Rv NIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDFG
MAV_0355|M.avium_104 NIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASNAGNLDFG
MAB_4544c|M.abscessus_ATCC_199 NVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSSGSSMHFG
MLBr_01244|M.leprae_Br4923 DVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSRGGFCTVT
:: **:*. :: .: : . * *: . . . .
Mflv_1058|M.gilvum_PYR-GCK FVGCRDRLPHLQRLAVYTGDALAELEAASQI-------------------
Mvan_5773|M.vanbaalenii_PYR-1 FVGCRDRLPRLQRLAVYTGDALGELEAASS--------------------
MUL_1193|M.ulcerans_Agy99 LVGCRRSVPHLQRLLLHLETSLYGLEQAVGL-------------------
MMAR_0529|M.marinum_M LVGCRRSVPHLQRLLLHLETSLHGLEQAVGL-------------------
MSMEG_6322|M.smegmatis_MC2_155 LVGCRRSVPHLQRLLGHLETSLKDLETATGA-------------------
TH_2030|M.thermoresistible__bu LVGARGSVPHLQRLLGHLEDSLQQLERAVGG-------------------
Mb3761c|M.bovis_AF2122/97 LVGCRRSVPHLQRLLAHLESSLKDLEQAVGI-------------------
Rv3734c|M.tuberculosis_H37Rv LVGCRRSVPHLQRLLAHLESSLKDLEQAVGI-------------------
MAV_0355|M.avium_104 LVGCRRSVPHLQRLLMHLESSLKDLERAVGE-------------------
MAB_4544c|M.abscessus_ATCC_199 LTGCRTSVPHLQRILAHLEDALTQLEESVA--------------------
MLBr_01244|M.leprae_Br4923 VRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSSGSPA
. * : : .: :
Mflv_1058|M.gilvum_PYR-GCK ------
Mvan_5773|M.vanbaalenii_PYR-1 ------
MUL_1193|M.ulcerans_Agy99 ------
MMAR_0529|M.marinum_M ------
MSMEG_6322|M.smegmatis_MC2_155 ------
TH_2030|M.thermoresistible__bu ------
Mb3761c|M.bovis_AF2122/97 ------
Rv3734c|M.tuberculosis_H37Rv ------
MAV_0355|M.avium_104 ------
MAB_4544c|M.abscessus_ATCC_199 ------
MLBr_01244|M.leprae_Br4923 GWLSSS