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MHTFKVAIIDPSTDAQGWSFDRFYAEAARRIHLLPMLRWKCVESPLGLNHPYWVEDPDFELHNHIHRVAC PAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLAEGKVALVMLVHHAYVDGVGAAWLMQQFYQPHRG VGAAEAPDYRPAPLPSWPTRLGWAVRDWPETVIGNVPKVATGLWRKFLFDRKRKSAGLPPHPSARQMQRT PINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCAAGALRRLLVDLDYDPDTHPLIGATPFAGE RPLGMQGLGNYATVDYCWLRSDIADPSARLQASREANTQMKENIKAVKEAGADFNSVMQVLPPWGIKIIR KAIHRSRGRFGFFGNVVLSNVPGPKETLYLDHWKVSNWFSTGQIADGTALNITMWSYCGQANICVLADRA VLDDGWRMFDYLVDELNSLTAVASTKEAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3161 | - | - | 100% (449) | hypothetical protein MUL_3161 |
| M. ulcerans Agy99 | MUL_1818 | - | 6e-43 | 29.61% (456) | hypothetical protein MUL_1818 |
| M. ulcerans Agy99 | MUL_1313 | - | 4e-41 | 30.13% (478) | hypothetical protein MUL_1313 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3114 | - | 1e-102 | 44.91% (432) | hypothetical protein Mb3114 |
| M. gilvum PYR-GCK | Mflv_2428 | - | 3e-47 | 32.17% (457) | hypothetical protein Mflv_2428 |
| M. tuberculosis H37Rv | Rv3087 | - | 1e-102 | 44.91% (432) | hypothetical protein Rv3087 |
| M. leprae Br4923 | MLBr_01244 | - | 3e-22 | 26.77% (396) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 6e-44 | 31.83% (421) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_2599 | - | 0.0 | 99.11% (449) | hypothetical protein MMAR_2599 |
| M. avium 104 | MAV_3015 | - | 1e-52 | 33.56% (450) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_0290 | - | 2e-47 | 31.52% (460) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_3760 | - | 8e-50 | 32.83% (463) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1065 | - | 3e-52 | 32.74% (446) | hypothetical protein Mvan_1065 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0290|M.smegmatis_MC2_155 ----------MQRLSGWDAFLLYSET-PNVHMHTLKIAIIDLEGIG---D
TH_3760|M.thermoresistible__bu ----------VKRLQGWDAVLLYSET-PNVHMHTLKVAVIDLSDV----T
Mflv_2428|M.gilvum_PYR-GCK --------MSMRRLNGMDAMLLYSET-PNLHTHTLKVAVIDATGYSAEHG
MUL_3161|M.ulcerans_Agy99 -------------------------------MHTFKVAIIDPSTDAQ---
MMAR_2599|M.marinum_M MTAPIKGVTRPQRLSGADAFMLGMET-PRAYMHTFKVAIIDPSTDAQ---
Mb3114|M.bovis_AF2122/97 ----------MRRLNGVDALMLYLDG-GSAYNHTLKISVLDPSTDPD---
Rv3087|M.tuberculosis_H37Rv ----------MRRLNGVDALMLYLDG-GSAYNHTLKISVLDPSTDPD---
MAV_3015|M.avium_104 ---------------------MYLES-PTQLLNICCVMELDPATMPG---
Mvan_1065|M.vanbaalenii_PYR-1 ----------MERLSGLDAGLLYSES-ATVPLHVCSVVELDTSTVPG---
MAB_0507|M.abscessus_ATCC_1997 ----------MQRLSGVDAAFWHAET-AGWHMHIGGLSIYDPTDAP----
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWN---
: *
MSMEG_0290|M.smegmatis_MC2_155 RTFGVEDFRKVLRGRLHKLDPFRFQLVDIPFKFHHPMWRENCDVDLEYHV
TH_3760|M.thermoresistible__bu HPFGLEDFRKVIASRLYKLDPFRYQLVEIPFKFHHPMWRENCEVDLDHHI
Mflv_2428|M.gilvum_PYR-GCK GEYGFDAFRQTIARRLHLLEPLRYRLIDIPWRLHHPMWLQDCPVDLDYHL
MUL_3161|M.ulcerans_Agy99 -GWSFDRFYAEAARRIHLLPMLRWKCVESPLGLNHPYWVEDPDFELHNHI
MMAR_2599|M.marinum_M -GWSFDRFYAEAARRIHLLPMLRWKCVESPLGLNHPYWVEDPDFELHNHI
Mb3114|M.bovis_AF2122/97 -GWSWPKARQMFEERAHLLPVFRLRYLPTPLGLHHPIWVEDPEFDLDAHV
Rv3087|M.tuberculosis_H37Rv -GWSWPKARQMFEERAHLLPVFRLRYLPTPLGLHHPIWVEDPEFDLDAHV
MAV_3015|M.avium_104 -GYTFERFRAALSRQLEAVPEFRLKLADTPLNLDHPVWVDDDRFDLGRHL
Mvan_1065|M.vanbaalenii_PYR-1 -GYSFERFRDELAKRIPALPEFRAKLADSQLNLDHPVWVEDKDFDLARHL
MAB_0507|M.abscessus_ATCC_1997 -DYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFHI
MLBr_01244|M.leprae_Br4923 ------RFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHV
: :* : * : : .: *:
MSMEG_0290|M.smegmatis_MC2_155 RPWQVRAPGGRRELDEAIGEIAGTPLDRSRPLWEMYFVEGLAG-GRIAVV
TH_3760|M.thermoresistible__bu RGMRVDPPGGRRELDEAVGRIASTPLDRRYPLWEMYFVEGLAN-GRVAVV
Mflv_2428|M.gilvum_PYR-GCK RRVRVPAPGGRRELDRVIGEIASTPLDRTRPLWEFHFAEGMAD-NRFALI
MUL_3161|M.ulcerans_Agy99 HRVACPAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLAE-GKVALV
MMAR_2599|M.marinum_M HRVACPAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLAE-GKVALV
Mb3114|M.bovis_AF2122/97 RRVVCPAPGGMAEFCALVEQIYAHPLDRDRPLWQTWVVEGLDG-GRVALV
Rv3087|M.tuberculosis_H37Rv RRVVCPAPGGMAEFCALVEQIYAHPLDRDRPLWQTWVVEGLDG-GRVALV
MAV_3015|M.avium_104 HRIALPSPGGPKELAEICGHVAGLPLDRDHPLWEMWVVEGRHGNDTLSVV
Mvan_1065|M.vanbaalenii_PYR-1 NRIALPAPGGREELAEVCGHIASTLLDRTKPLWEMWVIEGCAKADTLALM
MAB_0507|M.abscessus_ATCC_1997 RRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVEG-GRVATL
MLBr_01244|M.leprae_Br4923 RRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAA-GRAAML
. ** .. : :: *** . ** . : :
MSMEG_0290|M.smegmatis_MC2_155 NKIHHALADGIASANLLARGMDLREGPQRDR-DSYVTDPEPSKGELVRTA
TH_3760|M.thermoresistible__bu GKIHHALADGVASGNLMARGMDLQPGPQRDH-TFYRTDPPPGRSHLVRTA
Mflv_2428|M.gilvum_PYR-GCK GKVHHTLADGVASANLLARLMDLVDAPQDEREDPPAGCDDPSTLDLLREA
MUL_3161|M.ulcerans_Agy99 MLVHHAYVDGVGAAWLMQQFYQPHRGVGAAEAPDYRPAPLPSWPTRLGWA
MMAR_2599|M.marinum_M MLVHHAYVDGVGAAWLMQQFYQPHRGVGAAEAPDYRPAPLPSWPTRLGWA
Mb3114|M.bovis_AF2122/97 TLLHHAYSDGVGVLDMLAAFYNDAPDEAPVVAPPWEPPPLPSTRQRLGWA
Rv3087|M.tuberculosis_H37Rv TLLHHAYSDGVGVLDMLAAFYNDTPDEAPVVAPPWEPPPLPSTRQRLGWA
MAV_3015|M.avium_104 LKAHHAVVDGVGGANLLAQLCGTAPD-APPPEPAP----RTGTVNRLQIA
Mvan_1065|M.vanbaalenii_PYR-1 IKVHHAAVDGVSAAHLLHQLCDEVPD-APPPEPVE----GPGDATRLRIA
MAB_0507|M.abscessus_ATCC_1997 TKMHHAIVDGVSGAGLGEILLDIAPEPRPAPDDTVGSLVGLGLPSRERIL
MLBr_01244|M.leprae_Br4923 LQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQ---PIPQDLSRNDLM
*: **:. :
MSMEG_0290|M.smegmatis_MC2_155 FADHMRQIGRIPATIRYTAQGVARVRRSS--RKLSP--ELTRPFTP----
TH_3760|M.thermoresistible__bu FVDHLRQIGRIPSVMRYTYDGLRRVHRST--RKLSP--ELTRPFTP----
Mflv_2428|M.gilvum_PYR-GCK QLDHFRNIVELPSLVADAARGAARLRKRAKERREVP--GLAKPFNA----
MUL_3161|M.ulcerans_Agy99 VRDWPETVIGNVPKVATGLWRKFLFDRK-RKSAG--LPPHPSARQM----
MMAR_2599|M.marinum_M VRDWPETVIGNVPKVATGLWRKFLFDRK-RKSAG--LPPHPSARQM----
Mb3114|M.bovis_AF2122/97 LRDLPS-RLGKIAPTVRAVRDRVRIERE-FAKDGDRRVPPTFDRSA----
Rv3087|M.tuberculosis_H37Rv LRDLPS-RLGKIAPTVRAVRDRVRIERE-FAKDGDRRVPPTFDRSA----
MAV_3015|M.avium_104 AGGLIGA-ALRPWRLARVLPATALTLAETVLRARGGGQTMAAPFAA----
Mvan_1065|M.vanbaalenii_PYR-1 ADGLWRF-VTLPWQLTRVIPETTAVIAKTVTRALTG-KTMAAPFSA----
MAB_0507|M.abscessus_ATCC_1997 LSALVNVGVKTPYRVARLVQQTVRQQLAVFGMERKS----PGYFEA----
MLBr_01244|M.leprae_Br4923 LQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRV
MSMEG_0290|M.smegmatis_MC2_155 -----PPSFINHMITSKRKFATATIALADAKETSKKLGITLNDLVLAMSS
TH_3760|M.thermoresistible__bu -----PPTFLNHKIDATRTFATATLALSDVKATSRHLGVTINDLVLALSA
Mflv_2428|M.gilvum_PYR-GCK -----PPTFLNHVVSPVRTFATATLALSEVKETAKHLGVTFNDIVLAVAA
MUL_3161|M.ulcerans_Agy99 -----QRTPINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCAA
MMAR_2599|M.marinum_M -----QRTPINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCAA
Mb3114|M.bovis_AF2122/97 -----PPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLACVA
Rv3087|M.tuberculosis_H37Rv -----PPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLACVA
MAV_3015|M.avium_104 -----PATPFNGTFTRRRNVALAGVDLEDVKAVKRHFGVTVNDVVTAICA
Mvan_1065|M.vanbaalenii_PYR-1 -----PATRFNAQLTSERCLALVQLDLNDVKKVKDRFAVKVNDVVLALCA
MAB_0507|M.abscessus_ATCC_1997 -----PHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLAIVA
MLBr_01244|M.leprae_Br4923 LSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLV
: . * ..** :
MSMEG_0290|M.smegmatis_MC2_155 GALRTLQLRYD-GRADHPLLASVPMSFDFSPDR-IWGNRFSGVLVALPVD
TH_3760|M.thermoresistible__bu GALRKLLLRYD-GHADHPLLASVPVSFDFSPDR-ICGNYFTGMLVALPVD
Mflv_2428|M.gilvum_PYR-GCK GGLRELLLRYD-GRADRPIMATVPVSTDKSTDR-VTGNEIGGMMVSLPVH
MUL_3161|M.ulcerans_Agy99 GALRRLLVDLDYDPDTHPLIGATPFAGERPLGMQGLGNYATVDYCWLRSD
MMAR_2599|M.marinum_M GALRRLLVDLNYDPDTHPLIGATPFAGERPLGMQGLGNYATLDYCWLRSD
Mb3114|M.bovis_AF2122/97 GAVRRYLERCG-SPPTDAMVATMPLAVTPAAERAHPGNYSSVDYVWLRAD
Rv3087|M.tuberculosis_H37Rv GAVRRYLERCG-SPPTDAMVATMPLAVTPAAERAHPGNYSSVDYVWLRAD
MAV_3015|M.avium_104 GALRQFLADRD-ALPEVPLVASVPVSVH-GKSSRPGRNQTTWMLCRLETH
Mvan_1065|M.vanbaalenii_PYR-1 GALRGFLADRD-ELPDKPLIAVVPASVH-DISDRPGRNQLSGMFCNLHTD
MAB_0507|M.abscessus_ATCC_1997 GAVRDYLAKRD-EFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLATD
MLBr_01244|M.leprae_Br4923 GALRRYHEALGVSISTLPMAVPVNVRTEADVVG---SNRFVGVTLAAPLG
*.:* . .: *
MSMEG_0290|M.smegmatis_MC2_155 VADTGERVRRTREAANLAKESHQLIGPE--LVARWAAYMPPVPVEALFKR
TH_3760|M.thermoresistible__bu TAEPLDRIRATRDAALLAKESHQLIGPE--LISRWSQYLPPAPAERLFGW
Mflv_2428|M.gilvum_PYR-GCK VDDPLERVELTAVATTRAKENNDLLGPT--LQGRFLEYLPPPLAPTLFRA
MUL_3161|M.ulcerans_Agy99 IADPSARLQASREANTQMKENIKAVKEAGADFNSVMQVLPPWGIKIIRKA
MMAR_2599|M.marinum_M IADPSARLQASREANTQMKEHIKAVKEAGADFNSVMQVLPPWGIKIIRKA
Mb3114|M.bovis_AF2122/97 IADPLERLHATHLAAEATKQHFAQTKDA--DVGAVVELLPERLISGLARA
Rv3087|M.tuberculosis_H37Rv IADPLERLHATHLAAEATKQHFAQTKDA--DVGAVVELLPERLISGLARA
MAV_3015|M.avium_104 IDDPVHRLTTIAEKNAAAKEHAAAMGPT--LLQDWTQVAGQTVFGVARKL
Mvan_1065|M.vanbaalenii_PYR-1 VEDPVQRLRAIAESDTRAKEHSASLGPT--LLVDLAQSLSRGAFETLLGV
MAB_0507|M.abscessus_ATCC_1997 IDDPAERIQAIYEGTQGAKEMARAMSAH--QIMGLTDTTPPGLLQLAARA
MLBr_01244|M.leprae_Br4923 TNDPAARMQKIRSQMTQRRDEPAMNIIG--SLAPLMTVLPASVLDFIVDS
:. *: ::
MSMEG_0290|M.smegmatis_MC2_155 LSSKDGQ--NKVLNLNISNVPGPRERGKVGGATVTELYSVGPITAGSGLN
TH_3760|M.thermoresistible__bu LSRIDGQ--NKIQNLTVSNVMGPKERGRVGGALVTEIYSVGPLTAASGLN
Mflv_2428|M.gilvum_PYR-GCK QSKRADH--NRLMNVAISNVPGPRQRGHVGGAPVSEIYSVGVLSAGSAFN
MUL_3161|M.ulcerans_Agy99 IHRSRGR-FGFFGNVVLSNVPGPKETLYLDHWKVSNWFSTGQIADGTALN
MMAR_2599|M.marinum_M IHRSRGR-FGFFGNVVLSNVPGPKETLYLDHWKVSNWFSTGQIADGTALN
Mb3114|M.bovis_AF2122/97 NARTKGR-FDTFKNVVVSNVPGPREPRYLGRWRVDQWFSTGQISHGATLN
Rv3087|M.tuberculosis_H37Rv NARTKGR-FDTFKNVVVSNVPGPREPRYLGRWRVDQWFSTGQISHGATLN
MAV_3015|M.avium_104 LPRIPLP-DKPPHNLVLSNVAGPRHQLYFLGCRLDGMYPLGPIIAGAALN
Mvan_1065|M.vanbaalenii_PYR-1 LSHTPLT-HTAIHNCVISNVAGPTTTLYSGGAAITALYPLGPIFHGSGLN
MAB_0507|M.abscessus_ATCC_1997 YTASGLSRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALN
MLBr_01244|M.leprae_Br4923 VASSDVN---------ASNIPAYPGDTYFAGAKILRQYGIGPR-PGVAMM
**: . : * :
MSMEG_0290|M.smegmatis_MC2_155 ITVWSYVDQLNISVISDDATVDDPHEVTDAMLDEFREIRRTAGLSEKLTV
TH_3760|M.thermoresistible__bu ITVWSYVDQLNISVLSDGSTFDDPHEVTDAMVGEFIEIRGAAGLPGELTV
Mflv_2428|M.gilvum_PYR-GCK MTVWSYVDQLDIAVLSDDRTFNDPHEATDAMVHAFDELRQVCGL-ARPTT
MUL_3161|M.ulcerans_Agy99 ITMWSYCGQANICVLADRAVLDDGWRMFD----YLVDELNSLTAVASTKE
MMAR_2599|M.marinum_M ITMWSYCGQANICILADRAVLDDGWRMFD----YLVDELNSLTAVASTKE
Mb3114|M.bovis_AF2122/97 MTVWSYCDQFNLCVMADAVAVRNTWELVGGFRASHEELLAAARAQATPKE
Rv3087|M.tuberculosis_H37Rv MTVWSYCDQFNLCVMADAVAVRNTWELLGGFRASHEELLAAARAQATPKE
MAV_3015|M.avium_104 ITVMSLGGRLGVGILSCPDLVPDLWDLADAFPAALKELTNCVRPGRART-
Mvan_1065|M.vanbaalenii_PYR-1 ITVMSLGDTLNVGILSCPQLVDDLWDLADRFDGELTELLHHC--------
MAB_0507|M.abscessus_ATCC_1997 ITCFSYLEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI------
MLBr_01244|M.leprae_Br4923 AVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAV
. * . . . :
MSMEG_0290|M.smegmatis_MC2_155 VETAMPQ------------
TH_3760|M.thermoresistible__bu VETAMAR------------
Mflv_2428|M.gilvum_PYR-GCK VDTAMAPAPAPQP------
MUL_3161|M.ulcerans_Agy99 AA-----------------
MMAR_2599|M.marinum_M AA-----------------
Mb3114|M.bovis_AF2122/97 MAT----------------
Rv3087|M.tuberculosis_H37Rv MAT----------------
MAV_3015|M.avium_104 -------------------
Mvan_1065|M.vanbaalenii_PYR-1 -------------------
MAB_0507|M.abscessus_ATCC_1997 -------------------
MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS