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TAPIKGVTRPQRLSGADAFMLGMETPRAYMHTFKVAIIDPSTDAQGWSFDRFYAEAARRIHLLPMLRWKC VESPLGLNHPYWVEDPDFELHNHIHRVACPAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLAEGKV ALVMLVHHAYVDGVGAAWLMQQFYQPHRGVGAAEAPDYRPAPLPSWPTRLGWAVRDWPETVIGNVPKVAT GLWRKFLFDRKRKSAGLPPHPSARQMQRTPINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCA AGALRRLLVDLNYDPDTHPLIGATPFAGERPLGMQGLGNYATLDYCWLRSDIADPSARLQASREANTQMK EHIKAVKEAGADFNSVMQVLPPWGIKIIRKAIHRSRGRFGFFGNVVLSNVPGPKETLYLDHWKVSNWFST GQIADGTALNITMWSYCGQANICILADRAVLDDGWRMFDYLVDELNSLTAVASTKEAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2599 | - | - | 100% (479) | hypothetical protein MMAR_2599 |
| M. marinum M | MMAR_2634 | - | 2e-57 | 33.69% (469) | hypothetical protein MMAR_2634 |
| M. marinum M | MMAR_3298 | - | 8e-55 | 32.26% (468) | hypothetical protein MMAR_3298 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3114 | - | 1e-108 | 44.69% (452) | hypothetical protein Mb3114 |
| M. gilvum PYR-GCK | Mflv_5212 | - | 7e-52 | 31.91% (470) | hypothetical protein Mflv_5212 |
| M. tuberculosis H37Rv | Rv3087 | - | 1e-108 | 44.69% (452) | hypothetical protein Rv3087 |
| M. leprae Br4923 | MLBr_01244 | - | 5e-23 | 25.05% (463) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_1917 | - | 3e-48 | 30.70% (456) | hypothetical protein MAB_1917 |
| M. avium 104 | MAV_2240 | - | 2e-55 | 32.30% (483) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_0290 | - | 9e-54 | 32.92% (480) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_3760 | - | 8e-54 | 33.33% (483) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_3161 | - | 0.0 | 99.11% (449) | hypothetical protein MUL_3161 |
| M. vanbaalenii PYR-1 | Mvan_1065 | - | 7e-56 | 33.33% (465) | hypothetical protein Mvan_1065 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2599|M.marinum_M MTAPIKGVTRPQRLSGADAFMLGMET-PRAYMHTFKVAIIDPSTD-AQGW
MUL_3161|M.ulcerans_Agy99 -------------------------------MHTFKVAIIDPSTD-AQGW
Mb3114|M.bovis_AF2122/97 ----------MRRLNGVDALMLYLDG-GSAYNHTLKISVLDPSTD-PDGW
Rv3087|M.tuberculosis_H37Rv ----------MRRLNGVDALMLYLDG-GSAYNHTLKISVLDPSTD-PDGW
Mflv_5212|M.gilvum_PYR-GCK ----------MERLSGLDAGMLYSES-PTVPLHVCSVTELDTSTV-PGGY
Mvan_1065|M.vanbaalenii_PYR-1 ----------MERLSGLDAGLLYSES-ATVPLHVCSVVELDTSTV-PGGY
MAB_1917|M.abscessus_ATCC_1997 ----------MQRLSGLDASFLYLET-PTQPMHVCGVLELDTTTI-PGGY
MAV_2240|M.avium_104 -------MLRMQRLSGLDASFLYLET-SSQPMHVCSIIELDTSTV-PGGY
MSMEG_0290|M.smegmatis_MC2_155 ----------MQRLSGWDAFLLYSET-PNVHMHTLKIAIIDLEGIGDRTF
TH_3760|M.thermoresistible__bu ----------VKRLQGWDAVLLYSET-PNVHMHTLKVAVIDLSDV-THPF
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPD-----
: :*
MMAR_2599|M.marinum_M SFDRFYAEAARRIHLLPMLRWKCVESPLGLNHPYWVEDPDFELHNHIHRV
MUL_3161|M.ulcerans_Agy99 SFDRFYAEAARRIHLLPMLRWKCVESPLGLNHPYWVEDPDFELHNHIHRV
Mb3114|M.bovis_AF2122/97 SWPKARQMFEERAHLLPVFRLRYLPTPLGLHHPIWVEDPEFDLDAHVRRV
Rv3087|M.tuberculosis_H37Rv SWPKARQMFEERAHLLPVFRLRYLPTPLGLHHPIWVEDPEFDLDAHVRRV
Mflv_5212|M.gilvum_PYR-GCK TFAKFRDHLASRVPAIPEFRTKLADNDLNFDHPVWVEDDDFDLTRHLNRV
Mvan_1065|M.vanbaalenii_PYR-1 SFERFRDELAKRIPALPEFRAKLADSQLNLDHPVWVEDKDFDLARHLNRI
MAB_1917|M.abscessus_ATCC_1997 SFEKLRTKLAERVEGIPSFREKLADSRLNLDHPVWVDDDDFDIDRHLHHV
MAV_2240|M.avium_104 TFERLRDALVRRIRAVPPFREKLADSPLNLDHPVWVDDEDFDVDRHLHRI
MSMEG_0290|M.smegmatis_MC2_155 GVEDFRKVLRGRLHKLDPFRFQLVDIPFKFHHPMWRENCDVDLEYHVRPW
TH_3760|M.thermoresistible__bu GLEDFRKVIASRLYKLDPFRYQLVEIPFKFHHPMWRENCEVDLDHHIRGM
MLBr_01244|M.leprae_Br4923 -WNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRV
: :* : : * * : :.:: *:.
MMAR_2599|M.marinum_M ACPAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLA------EGKVA
MUL_3161|M.ulcerans_Agy99 ACPAPGDHKSLCAVMTTIYSAQLERDRPLWLMWVVEGLA------EGKVA
Mb3114|M.bovis_AF2122/97 VCPAPGGMAEFCALVEQIYAHPLDRDRPLWQTWVVEGLD------GGRVA
Rv3087|M.tuberculosis_H37Rv VCPAPGGMAEFCALVEQIYAHPLDRDRPLWQTWVVEGLD------GGRVA
Mflv_5212|M.gilvum_PYR-GCK ALPEPGGRDELAELCGRLIGMPLERSKPLWEMWVIEGVGGSAAREDGRLA
Mvan_1065|M.vanbaalenii_PYR-1 ALPAPGGREELAEVCGHIASTLLDRTKPLWEMWVIEGC----AKAD-TLA
MAB_1917|M.abscessus_ATCC_1997 GLPAPGGKAEIADMCGHIASLPLDRARPLWEMWVIETGD------TNRLV
MAV_2240|M.avium_104 AVPAPGGRAELSQICGHIAQTPLDRRRPLWEMWVIEGVAGTDCHRDGRLA
MSMEG_0290|M.smegmatis_MC2_155 QVRAPGGRRELDEAIGEIAGTPLDRSRPLWEMYFVEGLAG------GRIA
TH_3760|M.thermoresistible__bu RVDPPGGRRELDEAVGRIASTPLDRRYPLWEMYFVEGLAN------GRVA
MLBr_01244|M.leprae_Br4923 RVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAA------GRAA
** .. : :: *** .:* .
MMAR_2599|M.marinum_M LVMLVHHAYVDGVGAAWLMQQFYQPHRGVGAAEAPDYR-PAPLPSW----
MUL_3161|M.ulcerans_Agy99 LVMLVHHAYVDGVGAAWLMQQFYQPHRGVGAAEAPDYR-PAPLPSW----
Mb3114|M.bovis_AF2122/97 LVTLLHHAYSDGVGVLDMLAAFYNDAPDEAPVVAPPWE-PPPLPST----
Rv3087|M.tuberculosis_H37Rv LVTLLHHAYSDGVGVLDMLAAFYNDTPDEAPVVAPPWE-PPPLPST----
Mflv_5212|M.gilvum_PYR-GCK LLLKVHHAAVDGVSAADLLAKLLDTEPDAPPPDPVDAP-TGASTWE----
Mvan_1065|M.vanbaalenii_PYR-1 LMIKVHHAAVDGVSAAHLLHQLCDEVPDAPPPEPVEGP-GDATRLR----
MAB_1917|M.abscessus_ATCC_1997 VMTKMHHASVDGVTGANLMSALCGLEPDAEAPEPAPGV-GGANSLE----
MAV_2240|M.avium_104 VMTKVHHAGVDGVTGANLMSQLCATEPDAAPPEPAAGV-GGGAGWR----
MSMEG_0290|M.smegmatis_MC2_155 VVNKIHHALADGIASANLLARGMDLREGPQRDRDSYVTDPEPSKGE----
TH_3760|M.thermoresistible__bu VVGKIHHALADGVASGNLMARGMDLQPGPQRDHTFYRTDPPPGRSH----
MLBr_01244|M.leprae_Br4923 MLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLML
:: : ** **: :: .
MMAR_2599|M.marinum_M --PTRLGWAVRDWPETVIGNVPKVATGLWRKFLFDRKRKSAG--LPPHPS
MUL_3161|M.ulcerans_Agy99 --PTRLGWAVRDWPETVIGNVPKVATGLWRKFLFDRKRKSAG--LPPHPS
Mb3114|M.bovis_AF2122/97 --RQRLGWALRDLPS-RLGKIAPTVRAVRDRVRIEREFAKDGDRRVPPTF
Rv3087|M.tuberculosis_H37Rv --RQRLGWALRDLPS-RLGKIAPTVRAVRDRVRIEREFAKDGDRRVPPTF
Mflv_5212|M.gilvum_PYR-GCK --IAADGLWRVATRPWQLTRVVPVATSLVTNTVS---RALSG---TAMAL
Mvan_1065|M.vanbaalenii_PYR-1 --IAADGLWRFVTLPWQLTRVIPETTAVIAKTVT---RALTG---KTMAA
MAB_1917|M.abscessus_ATCC_1997 --IAVTGALKWASRPLKFAKLLPATIGVIPAWLE---RSKRG---EAMSA
MAV_2240|M.avium_104 --IAAGGLVRFAARPLRLASVVPDTAASVLATVR---RALDG---AAMAR
MSMEG_0290|M.smegmatis_MC2_155 --LVRTAFADHMRQIGRIPATIRYTAQGVARVRR-----SSRKLSPELTR
TH_3760|M.thermoresistible__bu --LVRTAFVDHLRQIGRIPSVMRYTYDGLRRVHR-----STRKLSPELTR
MLBr_01244|M.leprae_Br4923 QGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVL
: .
MMAR_2599|M.marinum_M ARQMQRTPINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCAAG
MUL_3161|M.ulcerans_Agy99 ARQMQRTPINVNLSAARTFVCDSVPLQHFSAVAKALGVTINDVFSSCAAG
Mb3114|M.bovis_AF2122/97 DRSAPPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLACVAG
Rv3087|M.tuberculosis_H37Rv DRSAPPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLACVAG
Mflv_5212|M.gilvum_PYR-GCK PFSAPSTPFNAPLTSDRNIAFAQLDLDDVKKVKNQAEVKVNDVVMALCAG
Mvan_1065|M.vanbaalenii_PYR-1 PFSAPATRFNAQLTSERCLALVQLDLNDVKKVKDRFAVKVNDVVLALCAG
MAB_1917|M.abscessus_ATCC_1997 PFSAPRTSFNSTITSRRNVGYAQLDLEDVRTVKNHFGVKVNDVVMAICAG
MAV_2240|M.avium_104 PFAAPTTVFNARISNRRCIAYAELNLDDVKAVKNHFGVKVNDVVMALVSG
MSMEG_0290|M.smegmatis_MC2_155 PFTPPPSFINHMITSKRKFATATIALADAKETSKKLGITLNDLVLAMSSG
TH_3760|M.thermoresistible__bu PFTPPPTFLNHKIDATRTFATATLALSDVKATSRHLGVTINDLVLALSAG
MLBr_01244|M.leprae_Br4923 SQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVG
: . * . . .:** : *
MMAR_2599|M.marinum_M ALRRLLVDLNYDPDTHPLIGATPFAGERPLGMQGLGNYATLDYCWLRSDI
MUL_3161|M.ulcerans_Agy99 ALRRLLVDLDYDPDTHPLIGATPFAGERPLGMQGLGNYATVDYCWLRSDI
Mb3114|M.bovis_AF2122/97 AVRRYLERCG-SPPTDAMVATMPLAVTPAAERAHPGNYSSVDYVWLRADI
Rv3087|M.tuberculosis_H37Rv AVRRYLERCG-SPPTDAMVATMPLAVTPAAERAHPGNYSSVDYVWLRADI
Mflv_5212|M.gilvum_PYR-GCK ALRGYLDERG-ALPDKPLIAVVPSSVHGQTDRPGR-NQLSGMFCNLHTDI
Mvan_1065|M.vanbaalenii_PYR-1 ALRGFLADRD-ELPDKPLIAVVPASVHDISDRPGR-NQLSGMFCNLHTDV
MAB_1917|M.abscessus_ATCC_1997 ALRKYLDDRG-ELPDNSLVAMVPVSVHEKSDRPGR-NQVSGMFSRLETNV
MAV_2240|M.avium_104 VLRQYLAERN-ALPDSSLVASVPISVHGKSDRPGR-NQVSAMFASLHTEI
MSMEG_0290|M.smegmatis_MC2_155 ALRTLQLRYD-GRADHPLLASVPMSFDFSPDRIWG-NRFSGVLVALPVDV
TH_3760|M.thermoresistible__bu ALRKLLLRYD-GHADHPLLASVPVSFDFSPDRICG-NYFTGMLVALPVDT
MLBr_01244|M.leprae_Br4923 ALRRYHEALG--VSISTLPMAVPVNVRTEADVVGS-NRFVGVTLAAPLGT
.:* . .: * *
MMAR_2599|M.marinum_M ADPSARLQASREANTQMKEHIKAVKEAGADFNSVMQVLPPWGIKIIRKAI
MUL_3161|M.ulcerans_Agy99 ADPSARLQASREANTQMKENIKAVKEAGADFNSVMQVLPPWGIKIIRKAI
Mb3114|M.bovis_AF2122/97 ADPLERLHATHLAAEATKQHFAQTKDA--DVGAVVELLPERLISGLARAN
Rv3087|M.tuberculosis_H37Rv ADPLERLHATHLAAEATKQHFAQTKDA--DVGAVVELLPERLISGLARAN
Mflv_5212|M.gilvum_PYR-GCK EDPLDRLYAIGASNVRAKEHSGSLGPSMLMDLAQSVSRTMFGWLLGGLSR
Mvan_1065|M.vanbaalenii_PYR-1 EDPVQRLRAIAESDTRAKEHSASLGPTLLVDLAQSLSRGAFETLLGVLSH
MAB_1917|M.abscessus_ATCC_1997 DDPVERLNAIAAANNIAKDHTAVLGATLLQDWSQFAAPAVFGTAMRVYSR
MAV_2240|M.avium_104 ADPVQRLKAIAHANSLAKEHSSAIGASLLQDWTQFAAPAVFGIAMRLYAR
MSMEG_0290|M.smegmatis_MC2_155 ADTGERVRRTREAANLAKESHQLIGPELVARWAAYMPPVPVEALFKRLSS
TH_3760|M.thermoresistible__bu AEPLDRIRATRDAALLAKESHQLIGPELISRWSQYLPPAPAERLFGWLSR
MLBr_01244|M.leprae_Br4923 NDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVAS
:. *: :: :
MMAR_2599|M.marinum_M HRSRGRFGFFGNVVLSNVPGPKETLYLDHWKVSNWFSTGQIADGTALNIT
MUL_3161|M.ulcerans_Agy99 HRSRGRFGFFGNVVLSNVPGPKETLYLDHWKVSNWFSTGQIADGTALNIT
Mb3114|M.bovis_AF2122/97 ARTKGRFDTFKNVVVSNVPGPREPRYLGRWRVDQWFSTGQISHGATLNMT
Rv3087|M.tuberculosis_H37Rv ARTKGRFDTFKNVVVSNVPGPREPRYLGRWRVDQWFSTGQISHGATLNMT
Mflv_5212|M.gilvum_PYR-GCK TSLG--NTAIHNVIISNVAGPPTTLYSGGAEITGLYPLGPIFPGSGLNIT
Mvan_1065|M.vanbaalenii_PYR-1 TPLT--HTAIHNCVISNVAGPTTTLYSGGAAITALYPLGPIFHGSGLNIT
MAB_1917|M.abscessus_ATCC_1997 IRLADRHPVIHNLVVSNVPGPQVPLYFLGAQVIGMYPLGPIFHGAALTVT
MAV_2240|M.avium_104 TRFTDSMP-VHNLVVSNVPGPQLPLYLLGCEVKAMYPLGPIFHGSGLNIT
MSMEG_0290|M.smegmatis_MC2_155 KDGQ---NKVLNLNISNVPGPRERGKVGGATVTELYSVGPITAGSGLNIT
TH_3760|M.thermoresistible__bu IDGQ---NKIQNLTVSNVMGPKERGRVGGALVTEIYSVGPLTAASGLNIT
MLBr_01244|M.leprae_Br4923 ----------SDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAV
: **: . : : * . : .
MMAR_2599|M.marinum_M MWSYCGQANICILADRAVLDDGWRMFD----YLVDELNSLTAVASTKEAA
MUL_3161|M.ulcerans_Agy99 MWSYCGQANICVLADRAVLDDGWRMFD----YLVDELNSLTAVASTKEAA
Mb3114|M.bovis_AF2122/97 VWSYCDQFNLCVMADAVAVRNTWELVGGFRASHEELLAAARAQATPKEMA
Rv3087|M.tuberculosis_H37Rv VWSYCDQFNLCVMADAVAVRNTWELLGGFRASHEELLAAARAQATPKEMA
Mflv_5212|M.gilvum_PYR-GCK VMSMGDKLNVGIISCPKLTDDLWDLADRFDAELADLLARS----------
Mvan_1065|M.vanbaalenii_PYR-1 VMSLGDTLNVGILSCPQLVDDLWDLADRFDGELTELLHHC----------
MAB_1917|M.abscessus_ATCC_1997 VMSLDGKLNVGLISCPDLMPDLGTLTDDFGVALEELKARI----------
MAV_2240|M.avium_104 AMSLRGKLDVGLIGCPDLVPDLWELADEFAVAMEELRAAAR---------
MSMEG_0290|M.smegmatis_MC2_155 VWSYVDQLNISVISDDATVDDPHEVTDAMLDEFREIRRTAGLSEKLTVVE
TH_3760|M.thermoresistible__bu VWSYVDQLNISVLSDGSTFDDPHEVTDAMVGEFIEIRGAAGLPGELTVVE
MLBr_01244|M.leprae_Br4923 LMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPA
* . : : . . :
MMAR_2599|M.marinum_M -----------------
MUL_3161|M.ulcerans_Agy99 -----------------
Mb3114|M.bovis_AF2122/97 T----------------
Rv3087|M.tuberculosis_H37Rv T----------------
Mflv_5212|M.gilvum_PYR-GCK -----------------
Mvan_1065|M.vanbaalenii_PYR-1 -----------------
MAB_1917|M.abscessus_ATCC_1997 -----------------
MAV_2240|M.avium_104 -----------------
MSMEG_0290|M.smegmatis_MC2_155 TAMPQ------------
TH_3760|M.thermoresistible__bu TAMAR------------
MLBr_01244|M.leprae_Br4923 SFAARSSGSPAGWLSSS