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M. thermoresistible (build 8) TH_3760 (-)

annotation: Diacylglycerol O-acyltransferase
coordinates: 3712572 - 3713987
length: 472

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3760--100% (472)Diacylglycerol O-acyltransferase
M. thermoresistible (build 8)TH_2477-3e-6532.98% (470) PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein
M. thermoresistible (build 8)TH_2030-2e-3730.28% (436) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0227-1e-9370.13% (231) hypothetical protein Mb0227
M. gilvum PYR-GCKMflv_0439-0.074.47% (470) hypothetical protein Mflv_0439
M. tuberculosis H37RvRv0221-0.071.55% (471) hypothetical protein Rv0221
M. leprae Br4923MLBr_01244-2e-2124.74% (473) hypothetical protein MLBr_01244
M. abscessus ATCC 19977MAB_1917-2e-6132.89% (453) hypothetical protein MAB_1917
M. marinum MMMAR_0464-0.072.82% (471) hypothetical protein MMAR_0464
M. avium 104MAV_4952-0.072.13% (470) acyltransferase, ws/dgat/mgat subfamily protein
M. smegmatis MC2 155MSMEG_0290-0.072.13% (470) acyltransferase, ws/dgat/mgat subfamily protein
M. ulcerans Agy99MUL_1818-1e-5030.02% (473) hypothetical protein MUL_1818
M. vanbaalenii PYR-1Mvan_0228-0.075.37% (475) hypothetical protein Mvan_0228

CLUSTAL 2.0.9 multiple sequence alignment


Mb0227|M.bovis_AF2122/97            ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDS-----D
Rv0221|M.tuberculosis_H37Rv         ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDS-----D
MMAR_0464|M.marinum_M               ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDP-----D
MAV_4952|M.avium_104                ----------MKRLSGWDSVLLYSEA-PNVHMHTIKAAVIELDA-----D
Mflv_0439|M.gilvum_PYR-GCK          ----------MKRLRGWDAVLLYSET-PSVHMHTLKLAVIELDD----LG
Mvan_0228|M.vanbaalenii_PYR-1       ----------MKRLSGWDAVLLYSET-PNVHMHTLKLAVIELDDTFAREG
TH_3760|M.thermoresistible__bu      ----------VKRLQGWDAVLLYSET-PNVHMHTLKVAVIDLSD-----V
MSMEG_0290|M.smegmatis_MC2_155      ----------MQRLSGWDAFLLYSET-PNVHMHTLKIAIIDLEG----IG
MAB_1917|M.abscessus_ATCC_1997      ----------MQRLSGLDASFLYLET-PTQPMHVCGVLELDTTTIPG---
MUL_1818|M.ulcerans_Agy99           ----------MRRLSSVDAAFWSAET-AGWHMHVGALAICDPTDAP----
MLBr_01244|M.leprae_Br4923          MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTP------
                                              . .* . *  :   *: .            :         

Mb0227|M.bovis_AF2122/97            RQEFGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
Rv0221|M.tuberculosis_H37Rv         RQEFGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
MMAR_0464|M.marinum_M               RRAFGVDAFRAVIGERMAKLEPFGYQLVDIPFKFHHPMWREHCEVDLDYH
MAV_4952|M.avium_104                RRSLDVAAFRQVIAGRLNKLDPFCYQLVEVPFSFHHPMWRENCEIDLDYH
Mflv_0439|M.gilvum_PYR-GCK          GAKFGVEELRKVIHGRLYKLDPFRYELVDIPFKFHHPMWRENAEVDLDYH
Mvan_0228|M.vanbaalenii_PYR-1       GATFGVEELRKVIHGRLYKLDPFRYQLIDIPFKFHHPMWRENAEVDLEYH
TH_3760|M.thermoresistible__bu      THPFGLEDFRKVIASRLYKLDPFRYQLVEIPFKFHHPMWRENCEVDLDHH
MSMEG_0290|M.smegmatis_MC2_155      DRTFGVEDFRKVLRGRLHKLDPFRFQLVDIPFKFHHPMWRENCDVDLEYH
MAB_1917|M.abscessus_ATCC_1997      --GYSFEKLRTKLAERVEGIPSFREKLADSRLNLDHPVWVDDDDFDIDRH
MUL_1818|M.ulcerans_Agy99           --DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFH
MLBr_01244|M.leprae_Br4923          ----DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFH
                                        .   :*  :      :  :  .:    :    * :  . :.::: *

Mb0227|M.bovis_AF2122/97            IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
Rv0221|M.tuberculosis_H37Rv         IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
MMAR_0464|M.marinum_M               IRPWQLRPPGGRRELDEAIGEIASTPLDRRYPLWEMYFVEGLANHRVAVV
MAV_4952|M.avium_104                IRPWRVSPPGGRRELDEAIGQIASTPLDRSRPLWEMYFVEGLANNRIAVV
Mflv_0439|M.gilvum_PYR-GCK          VRSVRVDAPGGRRELDEAVGRIASTPLDRSRPLWEMYLIEGLADGRIAVL
Mvan_0228|M.vanbaalenii_PYR-1       VRSCRVDAPGGRRELDEAVGRIASTPLDRSRPLWEMYLIEGLAGGRIAVL
TH_3760|M.thermoresistible__bu      IRGMRVDPPGGRRELDEAVGRIASTPLDRRYPLWEMYFVEGLANGRVAVV
MSMEG_0290|M.smegmatis_MC2_155      VRPWQVRAPGGRRELDEAIGEIAGTPLDRSRPLWEMYFVEGLAGGRIAVV
MAB_1917|M.abscessus_ATCC_1997      LHHVGLPAPGGKAEIADMCGHIASLPLDRARPLWEMWVIETGDTNRLVVM
MUL_1818|M.ulcerans_Agy99           VRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATL
MLBr_01244|M.leprae_Br4923          VRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAML
                                    ::   :  **   *: :    :    ::   ***   .:*     * . :

Mb0227|M.bovis_AF2122/97            AKIHHALADGVASANMMARGMDLLPGPEVGR--YVPDP--------APTK
Rv0221|M.tuberculosis_H37Rv         AKIHHALADGVASANMMARGMDLLPGPEVGR--YVPDP--------APTK
MMAR_0464|M.marinum_M               GKIHHALADGVASANLMARGMDLLPGPEGDP--YVSDP--------APTK
MAV_4952|M.avium_104                GKIHHALADGVASANLLARGMDLQPGPEAGP--YVCDP--------PPTT
Mflv_0439|M.gilvum_PYR-GCK          GKIHHALADGVASANLLARGMDLQDGPQVDRDSYATDP--------APSK
Mvan_0228|M.vanbaalenii_PYR-1       GKIHHALADGVASANLLARGMDLQDSPQADRDSYATDP--------APTR
TH_3760|M.thermoresistible__bu      GKIHHALADGVASGNLMARGMDLQPGPQRDHTFYRTDP--------PPGR
MSMEG_0290|M.smegmatis_MC2_155      NKIHHALADGIASANLLARGMDLREGPQRDRDSYVTDP--------EPSK
MAB_1917|M.abscessus_ATCC_1997      TKMHHASVDGVTGANLMSALCGLEPDAEAP-EPAPGVGGANS--LEIAVT
MUL_1818|M.ulcerans_Agy99           TKMHHAIVDGVSGAGLGEILLDVTPEPRPPQEETVGFVGFQIPRLERRAV
MLBr_01244|M.leprae_Br4923          LQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIP------QDLSRN
                                     :: ** .**: .  :     .:   .                       

Mb0227|M.bovis_AF2122/97            RQLLSAAFIDHLRHLGRIPATIRYTTQGLGRVRRSSRKLSPALTMPFTP-
Rv0221|M.tuberculosis_H37Rv         RQLLSAAFIDHLRHLGRIPATIRYTTQGLGRVRRSSRKLSPALTMPFTP-
MMAR_0464|M.marinum_M               RELMSSAFLDHLRHLGRIPATMRYTAQGLARVRRSSRKLSPELTRPFTP-
MAV_4952|M.avium_104                RQLMVSAFADHLRHVGRLPHTIRYTAQGLGRVRRSARKLSPELTRPFEP-
Mflv_0439|M.gilvum_PYR-GCK          GELVRTAFTDHLRQIRRFPDVVRYTAAGMRRVRSSGQKLSPELTRPFTP-
Mvan_0228|M.vanbaalenii_PYR-1       GELVRSAFTDHLRQIAKLPGVVRYTAQGVRRVQRSERKLSPELTRPFTP-
TH_3760|M.thermoresistible__bu      SHLVRTAFVDHLRQIGRIPSVMRYTYDGLRRVHRSTRKLSPELTRPFTP-
MSMEG_0290|M.smegmatis_MC2_155      GELVRTAFADHMRQIGRIPATIRYTAQGVARVRRSSRKLSPELTRPFTP-
MAB_1917|M.abscessus_ATCC_1997      GALKWA--SRPLKFAKLLPATIGVIPAWLERSKRGE-----AMSAPFSA-
MUL_1818|M.ulcerans_Agy99           GALINVGIMTPFRIARLVEQTVRQQIAALGVSARP--------PRYFDA-
MLBr_01244|M.leprae_Br4923          DLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSG
                                      :        .     .   :                        . . 

Mb0227|M.bovis_AF2122/97            --------PPTFMNR-----------------------------------
Rv0221|M.tuberculosis_H37Rv         --------PPTFMNHRLTPERRFATATLALIDVKATAKLLGATINDMVLA
MMAR_0464|M.marinum_M               --------PPTFMNHMLTPQRRFATATLALADVKQTGKQLGATINDMVLA
MAV_4952|M.avium_104                --------PPTFMNHKLTPERRFATATLALADVKETGKRLGATINDMVLA
Mflv_0439|M.gilvum_PYR-GCK          --------PPSFMNHQIDATRKFATATLALDDVKQTGKHLGATINDMVLA
Mvan_0228|M.vanbaalenii_PYR-1       --------PPTFMNHMVDATRRFATATVALDDVKQTGKQLGVTINDMVLA
TH_3760|M.thermoresistible__bu      --------PPTFLNHKIDATRTFATATLALSDVKATSRHLGVTINDLVLA
MSMEG_0290|M.smegmatis_MC2_155      --------PPSFINHMITSKRKFATATIALADAKETSKKLGITLNDLVLA
MAB_1917|M.abscessus_ATCC_1997      --------PRTSFNSTITSRRNVGYAQLDLEDVRTVKNHFGVKVNDVVMA
MUL_1818|M.ulcerans_Agy99           --------PKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA
MLBr_01244|M.leprae_Br4923          IRVLSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLA
                                              : :                                     

Mb0227|M.bovis_AF2122/97            -----IKKPLSKPSGRPP-PHTNRAPSS----------------MPLAM-
Rv0221|M.tuberculosis_H37Rv         MSTGALRTLLLRYDGKAE-PLLASVPVSYDFSPERISG-NRFTGMLVALP
MMAR_0464|M.marinum_M               MSTGALRNLLLRYDGRAE-PLLASVPVSYDFSPDRISG-NYFSGMMVALP
MAV_4952|M.avium_104                MSTGALRTLLLRYDGQAQ-PLLASVPVSFDFSPERISG-NRFTGMLVALP
Mflv_0439|M.gilvum_PYR-GCK          MSAGTLRKLLLRYDGQADHPLLASVPVSFDFSRDRISG-NYFTGVLVSIP
Mvan_0228|M.vanbaalenii_PYR-1       MSAGALRKLLLRYDGRADHALLASVPVSFDFSRDRISG-NYFTGVLVSLP
TH_3760|M.thermoresistible__bu      LSAGALRKLLLRYDGHADHPLLASVPVSFDFSPDRICG-NYFTGMLVALP
MSMEG_0290|M.smegmatis_MC2_155      MSSGALRTLQLRYDGRADHPLLASVPMSFDFSPDRIWG-NRFSGVLVALP
MAB_1917|M.abscessus_ATCC_1997      ICAGALRKYLDDRGELPDNSLVAMVPVSVHEKSDRPGR-NQVSGMFSRLE
MUL_1818|M.ulcerans_Agy99           TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA
MLBr_01244|M.leprae_Br4923          GLVGALRRYHEALG-VSISTLPMAVPVNVRTEADVVGS-NRFVGVTLAAP
                                          :      .  .  .     * .                :     

Mb0227|M.bovis_AF2122/97            --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv         ADSDDPLQRVRVCHENAVSAKESHQLLGPELISRWAAYWPPAGAEALFRW
MMAR_0464|M.marinum_M               TDCADPLERVQACHENALSAKESHQLLGPELISRWAAYWPPGATEAAFRW
MAV_4952|M.avium_104                VDHDDPLERVAACHQNAISAKESHQLMGPELVSRWAAYMPPAPTRAFFQW
Mflv_0439|M.gilvum_PYR-GCK          VELDDPVERVRAAHDAAVAGKESNNLLGPELVSQWSAYLPPAPAEALFRW
Mvan_0228|M.vanbaalenii_PYR-1       VDVEDPLERVSAAHTAAAAGKESNNLIGPELVSRWSAYFPPAPAEAMFRW
TH_3760|M.thermoresistible__bu      VDTAEPLDRIRATRDAALLAKESHQLIGPELISRWSQYLPPAPAERLFGW
MSMEG_0290|M.smegmatis_MC2_155      VDVADTGERVRRTREAANLAKESHQLIGPELVARWAAYMPPVPVEALFKR
MAB_1917|M.abscessus_ATCC_1997      TNVDDPVERLNAIAAANNIAKDHTAVLGATLLQDWSQFAAPAVFGTAMRV
MUL_1818|M.ulcerans_Agy99           THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA
MLBr_01244|M.leprae_Br4923          LGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDS
                                                                                      

Mb0227|M.bovis_AF2122/97            --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv         LSER---DGQNKVLNLNISNVPGPRERGRVGAALVTEIYSVGPLTAGSGL
MMAR_0464|M.marinum_M               ASSR---DGQNKVLNLNISNVPGPREHGRVGGALVTEIYSVGPLTAGSGL
MAV_4952|M.avium_104                ASAR---DGHNKILNLNISNVPGPRERGRVGGALVTEIYSVGPLTAGSGL
Mflv_0439|M.gilvum_PYR-GCK          LGTK---DGQNKVMNLPISNVPGPRERARVGGALVTEIYSVGPLTVGSGI
Mvan_0228|M.vanbaalenii_PYR-1       LSNK---DGQNKVMNLPISNVPGPRERARVGGALVTEIYSVGPLTAGSGL
TH_3760|M.thermoresistible__bu      LSRI---DGQNKIQNLTVSNVMGPKERGRVGGALVTEIYSVGPLTAASGL
MSMEG_0290|M.smegmatis_MC2_155      LSSK---DGQNKVLNLNISNVPGPRERGKVGGATVTELYSVGPITAGSGL
MAB_1917|M.abscessus_ATCC_1997      YSRIRLADRHPVIHNLVVSNVPGPQVPLYFLGAQVIGMYPLGPIFHGAAL
MUL_1818|M.ulcerans_Agy99           YTATGLSHNLAPIN-LVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVAL
MLBr_01244|M.leprae_Br4923          VASS----------DVNASNIPAYPGDTYFAGAKILRQYGIGPR-PGVAM
                                                                                      

Mb0227|M.bovis_AF2122/97            --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv         NITVWSYVDQLNISVLTDGSTVQDPHEVTAGMIADFIEIRRAAGLSVELT
MMAR_0464|M.marinum_M               NITVWSYVDQLNISVLTDGATVEDPHEVTEAMMADFVEIRRAAGLSAELT
MAV_4952|M.avium_104                NITVWSYVDQLNISVLTDGATCKDPHEVTEAMVQDFIEIRRAAGFSEDLT
Mflv_0439|M.gilvum_PYR-GCK          NITVWSYVDQLNISVLTDGKTLEDPHELTSAMLDDFVEIRRAAGLSEELT
Mvan_0228|M.vanbaalenii_PYR-1       NITVWSYVDQINISVLSDGKTLDDPHELTTAMVDEFIEIRRAAGLSTELT
TH_3760|M.thermoresistible__bu      NITVWSYVDQLNISVLSDGSTFDDPHEVTDAMVGEFIEIRGAAGLPGELT
MSMEG_0290|M.smegmatis_MC2_155      NITVWSYVDQLNISVISDDATVDDPHEVTDAMLDEFREIRRTAGLSEKLT
MAB_1917|M.abscessus_ATCC_1997      TVTVMSLDGKLNVGLISCPDLMPDLGTLTDDFGVALEELKARI-------
MUL_1818|M.ulcerans_Agy99           NITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL-----
MLBr_01244|M.leprae_Br4923          MAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHA
                                                                                      

Mb0227|M.bovis_AF2122/97            --------------------
Rv0221|M.tuberculosis_H37Rv         VVESAMAQA-----------
MMAR_0464|M.marinum_M               VIEAAMAQARSMNEGAGSA-
MAV_4952|M.avium_104                VVEAAMAPA-----------
Mflv_0439|M.gilvum_PYR-GCK          VVETALPN------------
Mvan_0228|M.vanbaalenii_PYR-1       VIETAMAN------------
TH_3760|M.thermoresistible__bu      VVETAMAR------------
MSMEG_0290|M.smegmatis_MC2_155      VVETAMPQ------------
MAB_1917|M.abscessus_ATCC_1997      --------------------
MUL_1818|M.ulcerans_Agy99           --------------------
MLBr_01244|M.leprae_Br4923          VPASFAARSSGSPAGWLSSS