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TSVQLSMGIPSFSAEPPPSWEHLTDWAQLLEGCGFDRVLVSEHIAFGAHMDAYANPATGGTAGGRQPTGP DGHWLEPLTTLTYLVARTERIRLGTNILLAALRPAAMLAKTLATMDVLSGGRIDIGVGVGWQREEYEAAG VDFDRRGAVLDQTLEVCQRLWRENEVSFESAGLNFERIHQMPKPAQPGGGVPIWVSGTVNRAVARRLARF GAGWIPWGPDARDVAAGIARMRAAVAHAGGDPNGFGVAGALRVKADADGRPDLADVAERTKTLRDAGVTE LRMTHWPLAPENRERDISAVVEAVRAATGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2498 | - | - | 100% (311) | hypothetical protein MUL_2498 |
| M. ulcerans Agy99 | MUL_3448 | - | 4e-24 | 28.36% (275) | oxidoreductase |
| M. ulcerans Agy99 | MUL_1043 | - | 5e-24 | 36.36% (187) | hypothetical protein MUL_1043 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 7e-23 | 33.18% (214) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4839 | - | 1e-27 | 32.16% (227) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 7e-23 | 33.18% (214) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00269 | - | 1e-11 | 26.73% (202) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-32 | 36.75% (234) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1377 | - | 1e-177 | 97.11% (311) | hypothetical protein MMAR_1377 |
| M. avium 104 | MAV_2935 | - | 1e-31 | 35.46% (251) | hypothetical protein MAV_2935 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 5e-31 | 37.39% (230) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_2945 | - | 6e-28 | 31.88% (276) | PUTATIVE luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 2e-27 | 31.06% (264) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 ----------MQFGVLTFVTDEGIGP---AELGAALEHRGFESLFLAEHT
Rv3079c|M.tuberculosis_H37Rv ----------MQFGVLTFVTDEGIGP---AELGAALEHRGFESLFLAEHT
MUL_2498|M.ulcerans_Agy99 -----MTSVQLSMGIPSFSAEPPPSWEHLTDWAQLLEGCGFDRVLVSEHI
MMAR_1377|M.marinum_M -----MTSVQLSMGIPSFSAEPPPSWEHLTDWAQLLEGCGFDRVLVSEHI
TH_2945|M.thermoresistible__bu MKFTFALPHMMELDAMMQPWEMAVTGADQTRMARRAEELGFDMIAVPEHI
Mvan_5167|M.vanbaalenii_PYR-1 MRLVFALPHMLRLPAMSQPWEASVTGADQTRMARCADQWGYDMIAVPEHF
Mflv_4839|M.gilvum_PYR-GCK ---------------------------MIDAVAASAERSGFETLWFGDQV
MSMEG_2811|M.smegmatis_MC2_155 ----------MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHV
MAB_0366|M.abscessus_ATCC_1997 ---------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHA
MAV_2935|M.avium_104 --------------MAPVADGVTADPDWMVAFARHLEACGFESIVAVEHT
MLBr_00269|M.leprae_Br4923 ---------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHF
. : * ::
Mb3106c|M.bovis_AF2122/97 HIPVNTQSPYPGG-------GPIPEKYYRTLDPFVALAAAAATTQSLVLG
Rv3079c|M.tuberculosis_H37Rv HIPVNTQSPYPGG-------GPIPEKYYRTLDPFVALAAAAATTQSLVLG
MUL_2498|M.ulcerans_Agy99 AFGAHMDAYANPATGGTAGGRQPTGPDGHWLEPLTTLTYLVARTERIRLG
MMAR_1377|M.marinum_M AFGAHMDAYANPATGGTAGGRQPTGPDGHWLEPLTTLTYLAARTERIRLG
TH_2945|M.thermoresistible__bu VMPREHVDLSG----------------GHWLHSTIAQAYFAGATERITLN
Mvan_5167|M.vanbaalenii_PYR-1 VIPAEHVELSG----------------PHYLQSTVAQAYLAGATERIRLN
Mflv_4839|M.gilvum_PYR-GCK VMADEDGPHHPYR----DDGEIPASAQTDWLDPLIALSFAAAATNRIELA
MSMEG_2811|M.smegmatis_MC2_155 VMVDRPRSRYPYS----ADGRIAVAADADWLDPMIALSFAAAATSTIRIA
MAB_0366|M.abscessus_ATCC_1997 VVIGDTQSTYPYS----PTGQSHLPDDIDIPDPLELLSFVAAATTTLGLS
MAV_2935|M.avium_104 VLLTRYDSVYPYD----SSGRVGLAPDCPIPDPLDLLAFLAGHTTRLGLA
MLBr_00269|M.leprae_Br4923 QPWRHQGGHASFS--------------------LSWMTAVGERTNRILLG
: * : :
Mb3106c|M.bovis_AF2122/97 TGIALIPERD-PIVTAKEVASLDLVSQGRFRFGVGVGWLREEVAN----H
Rv3079c|M.tuberculosis_H37Rv TGIALIPERD-PIVTAKEVASLDLVSQGRFRFGVGVGWLREEVAN----H
MUL_2498|M.ulcerans_Agy99 TNILLAALRP-AAMLAKTLATMDVLSGGRIDIGVGVGWQREEYEA----A
MMAR_1377|M.marinum_M TNILLAALRP-AAVLAKTLATMDVLSGGRIDIGVGVGWQREEYEA----A
TH_2945|M.thermoresistible__bu SCVTILPLQH-PLVTAKALATADWLSGGRMMVTFGVGWLQREFEL----L
Mvan_5167|M.vanbaalenii_PYR-1 SCITVLPLQH-PVVLAKALATADWMSGGRMMVTFGVGWLQGEFEA----L
Mflv_4839|M.gilvum_PYR-GCK TGVLVLPERN-PVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDA----L
MSMEG_2811|M.smegmatis_MC2_155 TGVLLLPEHN-PVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEA----L
MAB_0366|M.abscessus_ATCC_1997 TGVLVLPDHH-PVVLAKRLATLDRLSRGRLRICAGVGWMREEIEA----C
MAV_2935|M.avium_104 TGVLVLPNHH-PVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRA----C
MLBr_00269|M.leprae_Br4923 TSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGA
: : . : . : .: .: . : .*. . * * *
Mb3106c|M.bovis_AF2122/97 GVDPAVRGRVIDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVT
Rv3079c|M.tuberculosis_H37Rv GVDPAVRGRVIDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVT
MUL_2498|M.ulcerans_Agy99 GVDFDRRGAVLDQTLEVCQRLWRE---NEVSFESAGLNFERIHQMPKPAQ
MMAR_1377|M.marinum_M GADFDRRGAVLDQALEVCQRLWRE---NEVSFESVGLNFERIHQMPKPTQ
TH_2945|M.thermoresistible__bu GVPFRKRGRIADEYLAAIIELWTQ---DEPSFAGQFVSFEDVVFEPKPIQ
Mvan_5167|M.vanbaalenii_PYR-1 GVPFRERGRMADEYLAVIKELWTS---DAPSFEGKYVSFREVAFEPKPVQ
Mflv_4839|M.gilvum_PYR-GCK GVPFASRGARLAEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQ-
MSMEG_2811|M.smegmatis_MC2_155 GVPFARRGARTAEYVEAMRTLWRQ---DVADFTGEFAAFDAVRLHPKPS-
MAB_0366|M.abscessus_ATCC_1997 GGDFDRRGRAADEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPVR
MAV_2935|M.avium_104 GADFDNRGRRADEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPVA
MLBr_00269|M.leprae_Br4923 WPEFKERFARLRESVRLMRELWRG---DRVDFDGDYYQLKGASIYDVPE-
* : : :* .. . : *
Mb3106c|M.bovis_AF2122/97 KPY-PPLYVGGGPA--NFPRIARLNAGWIAISPSP--QRLSGPLQRLR--
Rv3079c|M.tuberculosis_H37Rv KPY-PPLYVGGGPA--NFPRIARLNAGWIAISPSP--QRLSGPLQRLR--
MUL_2498|M.ulcerans_Agy99 PGGGVPIWVSGTVNRAVARRLARFGAGWIPWGPDA--RDVAAGIARMRAA
MMAR_1377|M.marinum_M PGG-VPIWVSGTVNRAVARRLARFGAGWIPWGPDA--RDVAAGIARMRAA
TH_2945|M.thermoresistible__bu QPH-PPIWIGGDSD-AALRRAARFASGWFTFLTKP--EDIAARVDIITSQ
Mvan_5167|M.vanbaalenii_PYR-1 KPH-LPIWIGGDAD-AALRRAAKYASGWWSFLTPP--EKLAERLDFIKSQ
Mflv_4839|M.gilvum_PYR-GCK GRS-IPVVLGGNSD-AALRRVAEWGDGWYGFDLADV-EEAAFRASKLRSM
MSMEG_2811|M.smegmatis_MC2_155 AGS-IPIIVGGNGD-RALARVASWGDGWYGFNLDGV-AAVGERMDMLRRL
MAB_0366|M.abscessus_ATCC_1997 PQG-VPLYIGGHSK-AAARRAGRLGSGFQPLGLVG--DDLTAAVGVMRAA
MAV_2935|M.avium_104 AER-FPVHIGGHSR-AAARRAGRFGDGFQPLGVTG--ARLASLIGLMRDE
MLBr_00269|M.leprae_Br4923 --GGVPIYIAAGGP-EVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEG
*: :.. . *: :
Mb3106c|M.bovis_AF2122/97 -AMAGGDVPVTVCQWGEAAAK-----------------DLEGYRHLGVER
Rv3079c|M.tuberculosis_H37Rv -AMAGGDVPVTVCQWGEAAAK-----------------DLEGYRHLGVER
MUL_2498|M.ulcerans_Agy99 VAHAGGDPNGFGVAGALRVKA------DADGRP--DLADVAERTKTLRDA
MMAR_1377|M.marinum_M VAHAGGDPNGFGVAGALRVKA------DADGRP--DLADVAERAKTLRDA
TH_2945|M.thermoresistible__bu PEYDGRPFDVMHGLGTNRVGEGHVPTGDRGAWPGMSAAELIDRIGALHEH
Mvan_5167|M.vanbaalenii_PYR-1 PDYDGRPFDVVHGLGTNRVGEGHVAQHDPDARPGMSAAEIVDRLSWLGAQ
Mflv_4839|M.gilvum_PYR-GCK CREFGRDP--TELKLSVALHD-------------PVPADAVRLADAGIDE
MSMEG_2811|M.smegmatis_MC2_155 CARAGRDV--DDLHCAVALQA-------------PAVGDIPALVDLGVDE
MAB_0366|M.abscessus_ATCC_1997 AVDAGRDPRGLDLVLGHGLHR-------------VDQAALDQAAHAGAGR
MAV_2935|M.avium_104 AVAAGRDPAALEVSLGHSVSK-------------IDAERAARLADQGADR
MLBr_00269|M.leprae_Br4923 AAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDD
*
Mb3106c|M.bovis_AF2122/97 --VLLELP---------------TEPRDPTLRYLDKLQAELARLA-----
Rv3079c|M.tuberculosis_H37Rv --VLLELP---------------TEPRDPTLRYLDKLQAELARLA-----
MUL_2498|M.ulcerans_Agy99 GVTELRMT---------------HWPLAPENRERDISAVVEAVRAATGG-
MMAR_1377|M.marinum_M GVTELRMT---------------HWPLAPESRERDISAVVEAVRAATGG-
TH_2945|M.thermoresistible__bu GVTYTSVP---------------IPPVRGVEEYLDYSQWVMEEIAPNVP-
Mvan_5167|M.vanbaalenii_PYR-1 GVTVSAVP---------------IPKVRGVEEYLDYAQWVIEEIKPQVP-
Mflv_4839|M.gilvum_PYR-GCK LVLVAGPP---------------ADPIAAEAWIADLAGQWMRVRT-----
MSMEG_2811|M.smegmatis_MC2_155 LVIVESPP---------------QDPDVAADWVDALADRWITCI------
MAB_0366|M.abscessus_ATCC_1997 MLLSASRR---------------ATTLEAVLEEMAGCATRLELG---GPR
MAV_2935|M.avium_104 LVLAMPP----------------TSDIEQAKDMLSACAQRLSLRPVSGP-
MLBr_00269|M.leprae_Br4923 PIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPG
Mb3106c|M.bovis_AF2122/97 ----------------------
Rv3079c|M.tuberculosis_H37Rv ----------------------
MUL_2498|M.ulcerans_Agy99 ----------------------
MMAR_1377|M.marinum_M ----------------------
TH_2945|M.thermoresistible__bu ----------------------
Mvan_5167|M.vanbaalenii_PYR-1 ----------------------
Mflv_4839|M.gilvum_PYR-GCK ----------------------
MSMEG_2811|M.smegmatis_MC2_155 ----------------------
MAB_0366|M.abscessus_ATCC_1997 ----------------------
MAV_2935|M.avium_104 ----------------------
MLBr_00269|M.leprae_Br4923 HNQRRFLELFEKDLAPRLRRLG