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MRAAYIQQRGPAENIRYGTLSEPVAQPGEVIVQVDAVAVNPVDTFVRSGSYPTEIPLPFVVGRDLVGRVV HGAAGFQAGEKVWCGSLGYDGRQGATAELVAVPAERLYRLPVQVDPLAAVAVLHPASTAYLATVEYGEVR SGETVLILGAGGNVGSAAVALAVGSGAMVIAVASRRSLDRCAQLGAHEVYDYTADWVPQVSKAHHGAIDV CIDTSGVNDVAMAVDLLAPHGRIVLLSGDGTPETQRAVPLGPLYRKSGSLRGFVMSRATVRQLTDAAQRI AMLLGTGEITPNIIDLMHFSETARAHRRIETEVMGGTRLVLLPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0285 | - | - | 100% (324) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1112c | - | 1e-25 | 28.30% (311) | putative quinone oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 2e-25 | 34.02% (241) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0154 | - | 1e-26 | 33.06% (242) | putative quinone oxidoreductase (NADPH:quinone oxidoreductase) |
| M. gilvum PYR-GCK | Mflv_2449 | - | 1e-29 | 32.83% (329) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv0149 | - | 2e-26 | 33.06% (242) | quinone oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 2e-19 | 24.92% (325) | putative oxidireductase |
| M. marinum M | MMAR_0361 | - | 3e-27 | 32.37% (241) | quinone oxidoreductase |
| M. avium 104 | MAV_3325 | - | 4e-28 | 30.36% (336) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4828 | - | 1e-28 | 33.12% (314) | alcohol dehydrogenase, zinc-binding |
| M. thermoresistible (build 8) | TH_3440 | - | 1e-25 | 28.66% (335) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_4387 | - | 5e-28 | 32.52% (326) | quinone oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4202 | - | 2e-25 | 31.53% (314) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3325|M.avium_104 -----------------------------------------------MHA
TH_3440|M.thermoresistible__bu VQTAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKA
Mb0154|M.bovis_AF2122/97 -----------------------------------------------MKA
Rv0149|M.tuberculosis_H37Rv -----------------------------------------------MKA
MMAR_0361|M.marinum_M -----------------------------------------------MKA
Mflv_2449|M.gilvum_PYR-GCK -----------------------------------------------MRA
Mvan_4202|M.vanbaalenii_PYR-1 -----------------------------------------------MRA
MSMEG_4828|M.smegmatis_MC2_155 -----------------------------------------------MRA
MUL_4387|M.ulcerans_Agy99 -----------------------------------------------MRA
MAB_0285|M.abscessus_ATCC_1997 -----------------------------------------------MRA
MLBr_00118|M.leprae_Br4923 -----------------------------------------------MHA
*:*
MAV_3325|M.avium_104 IEVSETGGPEVLRYVETPTPTAGPGQVLIKAEAIGVNYIDTYFRSGQYPR
TH_3440|M.thermoresistible__bu IEVRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
Mb0154|M.bovis_AF2122/97 CVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGEYQL
Rv0149|M.tuberculosis_H37Rv CVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGEYQL
MMAR_0361|M.marinum_M CVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCFPDLLLTKGEYQL
Mflv_2449|M.gilvum_PYR-GCK AMCREYGPPEVVRVEDVAEPVAGPGQIGVRVDAAAVNFPDVLLVAGTYQI
Mvan_4202|M.vanbaalenii_PYR-1 AVCPQYGPPEVVRVEERPEPSAGPGQVVVRVEAAAVNFPDVLLVADSYQV
MSMEG_4828|M.smegmatis_MC2_155 AVCPRYGPPEVVRVEELPVPELGPDQVRVRVGAAAVNFPDVLLVADRYQA
MUL_4387|M.ulcerans_Agy99 IVCDAYGPPEDLVLDEVPDPVPAPGQVLVRVRAVAVNFPDVLFIAGKYQI
MAB_0285|M.abscessus_ATCC_1997 AYIQQRGPAENIRYGTLSEPVAQPGEVIVQVDAVAVNPVDTFVRSGSYPT
MLBr_00118|M.leprae_Br4923 IVAES---ANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGKYPH
.. : .:: : . * .* * . *
MAV_3325|M.avium_104 ELP--FIIGQELCG-TVAAAGDGVDGFKVGD-RVVSAAATGGYAEYATAP
TH_3440|M.thermoresistible__bu EVP--FIVGTEVCG-TVEAVGDGVAALRVGD-RVLTDKANGAYAEYTVAP
Mb0154|M.bovis_AF2122/97 KLTPPFVPGMETAG-VVRSAPS-DAGFHVGE-RVSAFGVLGGYAEQIAVP
Rv0149|M.tuberculosis_H37Rv KLTPPFVPGMETAG-VVRSAPS-DAGFHVGE-RVSAFGVLGGYAEQIAVP
MMAR_0361|M.marinum_M KLPPPFVPGLETAG-VVRSAPA-RSGFRVGE-RVSAFGVLGGYAEQVAVP
Mflv_2449|M.gilvum_PYR-GCK SVPPPFVPGSEFAG-VVDEIGPGTEGFTIGD-RVSGTAMFGAFAERTVVD
Mvan_4202|M.vanbaalenii_PYR-1 SVAPPFVPGSEFTG-VVDEIGPHTTGFTVGE-RVAGTGMFGAFAERVVAD
MSMEG_4828|M.smegmatis_MC2_155 TVPVPFVPGSEFAG-VVTETADGVTDFAVGD-RVVGTGMHGAFAEEVCVD
MUL_4387|M.ulcerans_Agy99 KIPPPFVPGNEIAG-EVVGAGAGVI-LVPGQ-RVFGT-TFGAFAELALLD
MAB_0285|M.abscessus_ATCC_1997 EIPLPFVVGRDLVGRVVHGAAGFQAGEKVWCGSLGYDGRQGATAELVAVP
MLBr_00118|M.leprae_Br4923 PPGASAIIGMEVAG-VVAAVSSGVTEWSVGQ-EVCALLAGGGYAEYVAVP
: * : * * : *. **
MAV_3325|M.avium_104 ASLTAHVPDGVAADVAASALLKGLTAHYLLTSVYPVQAGDTVLVHAGAGG
TH_3440|M.thermoresistible__bu ADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHAGAGG
Mb0154|M.bovis_AF2122/97 VANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAAGG
Rv0149|M.tuberculosis_H37Rv VANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAAGG
MMAR_0361|M.marinum_M VSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGAGG
Mflv_2449|M.gilvum_PYR-GCK AAALAPIPDGVDARTAAAFGVAYRTAYHTLRSVARVSEGDELVVLGAGGG
Mvan_4202|M.vanbaalenii_PYR-1 AAGLTPVPDGVDARTAAAFGVAHRTAYHALRSTARLSAGDELVVLGAGGG
MSMEG_4828|M.smegmatis_MC2_155 ASCLQRAVERLDDRGAAASGVAHRTAFHALRSVARVSTGDDVVVLGAGGG
MUL_4387|M.ulcerans_Agy99 GAAAQPIPDDADFASAAAFGVTYRTAYHALRSVAQVSQGDWVVVLGAAGG
MAB_0285|M.abscessus_ATCC_1997 AERLYRLPVQVDPLAAVAVLHPASTAYLATVEYGEVRSGETVLILGAGGN
MLBr_00118|M.leprae_Br4923 ASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGGTSG
.. * : *: ::: .. ..
MAV_3325|M.avium_104 VGLILTQWAHLLGA-RVITTVSTPEKARRSAQAGANEVLSYPDDADEFGN
TH_3440|M.thermoresistible__bu VGLILTQWATHLGA-RVITTVSTPQKAELSRKAGAAEVLDYPTDPEEFGA
Mb0154|M.bovis_AF2122/97 VGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEG---WAQ
Rv0149|M.tuberculosis_H37Rv VGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEG---WAQ
MMAR_0361|M.marinum_M VGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEG---WVD
Mflv_2449|M.gilvum_PYR-GCK VGLAAVQLGVALGA-NVTAVASSAEKLAAAAEYGAAHLVDHREQ--DLRA
Mvan_4202|M.vanbaalenii_PYR-1 VGLATVQLGVALGA-RVTAVASSNEKLAVAGGYGAATLINHRDG--ELRQ
MSMEG_4828|M.smegmatis_MC2_155 VGLAAVQIAAALGA-RVTAVASSSEKLDAAARYGAHHLVDHTAG--PLRA
MUL_4387|M.ulcerans_Agy99 VGLAAVDLAVAMGA-RVLAAASSPEKLGLCRQRGAEAVVDYDQE--DLKL
MAB_0285|M.abscessus_ATCC_1997 VGSAAVALAVGSGA--MVIAVASRRSLDRCAQLGAHEVYDYTAD----WV
MLBr_00118|M.leprae_Br4923 IGSHGIQVARALGA-KVAVTAGSEEKLEFCRALGAQITINYRDE----DF
:* . * : . **
MAV_3325|M.avium_104 RIRALTDGAGVAAVYDGVGASTFDASLASLAVRGTLALFG--AASGPVPP
TH_3440|M.thermoresistible__bu RIRDLTGGEGVPVVYDGVGRSTFDASLASLAVRGTLALFG--AASGPVPP
Mb0154|M.bovis_AF2122/97 QVRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIG--FAAGAVPT
Rv0149|M.tuberculosis_H37Rv QVRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIG--FAAGAVPT
MMAR_0361|M.marinum_M EVHKHTHGRGVDIVVDPIGGPVFDDAIRALAIDGKLLAIG--FAAGSIPT
Mflv_2449|M.gilvum_PYR-GCK ALRTAVP-DGADVVIDPVGGRLSEPALRSLGRGGRFVTVG--FASGEIPR
Mvan_4202|M.vanbaalenii_PYR-1 ALRQAIP-DGADVVVDPVGGDVSEPALRSLGRGGRFVSVG--FASGVIPR
MSMEG_4828|M.smegmatis_MC2_155 ALRDAVP-DGADAVLDPVGGDLSEPALRALRRGGRFVTIG--FASGAIPR
MUL_4387|M.ulcerans_Agy99 RIRELTG-ESARVVLDPVGGSYAEPALRGLARGGIFVTLG--YAAGSIPA
MAB_0285|M.abscessus_ATCC_1997 PQVSKAHHGAIDVCIDTSGVNDVAMAVDLLAPHGRIVLLSGDGTPETQRA
MLBr_00118|M.leprae_Br4923 VARLQQQNGGADVILDIMGAAYLDRNIDALAIDGQLIVIG--LQGGVKGE
. * * : * * : ..
MAV_3325|M.avium_104 FDPQRLNAAGSVFLTRPSLAHFIR----TGQEFSWRAEELFAAIAAGDIT
TH_3440|M.thermoresistible__bu FDPQRLNAAGSVYLTRPSLVHFTR----TPDEFGWRAGEFLSAVADGTLT
Mb0154|M.bovis_AF2122/97 LKVNRLLVRNISVVGVGWGEYLNA----VPGSAALFAWGLNQLVFLG-LR
Rv0149|M.tuberculosis_H37Rv LKVNRLLVRNISVVGVGWGEYLNA----VPGSAALFAWGLNQLVFLG-LR
MMAR_0361|M.marinum_M LAVNRLLRRNVGVLGVAWGEYLNR----VPGSVYLFSWGLNHLVSLG-LR
Mflv_2449|M.gilvum_PYR-GCK IPLNLVLLKGVQVLGFQFQDVP-------GDEFVRNDHELRALLSARRVT
Mvan_4202|M.vanbaalenii_PYR-1 IPLNLVLIKGVHVLGFQFQDVP-------ADEFTRNEVELRELLVSGRVK
MSMEG_4828|M.smegmatis_MC2_155 IPLNLVLVKGVQILGFAFQDVP-------PEEFARNESELGELLASGAVT
MUL_4387|M.ulcerans_Agy99 IPLNLVMLKNLTIRGMEIRTFMGD----YPDECARDVAELSQMFAAGKIR
MAB_0285|M.abscessus_ATCC_1997 VPLGPLYRKSGSLRGFVMSRAT-------VRQLTDAAQRIAMLLGTGEIT
MLBr_00118|M.leprae_Br4923 LNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVR
. : : . :
MAV_3325|M.avium_104 VEVGGRYPLADAARAHRDLQGRKTTGSIVLLP-------------
TH_3440|M.thermoresistible__bu ITVGERYPLAEAERAHRDLEGRKTVGSVVLLP-------------
Mb0154|M.bovis_AF2122/97 PPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
Rv0149|M.tuberculosis_H37Rv PPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
MMAR_0361|M.marinum_M PPPPQRFPLSEAQAALQSLADGAVLGKIVLEP-------------
Mflv_2449|M.gilvum_PYR-GCK PHVGAVYPLEEVAAALRHVGEGRAIGKVLIDVPA-----------
Mvan_4202|M.vanbaalenii_PYR-1 PHVGAVYSLDDTVAALRHVSDGRAIGKVVIDLS------------
MSMEG_4828|M.smegmatis_MC2_155 PHIGAVYPLVEVAAALRHVAEGRAVGKVVLDVSRVR---------
MUL_4387|M.ulcerans_Agy99 PHIGARFPLADTPAALRYVAERKVLGKVVIDVA------------
MAB_0285|M.abscessus_ATCC_1997 PNIIDLMHFSETARAHRRIETEVMGGTRLVLLPA-----------
MLBr_00118|M.leprae_Br4923 PIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
. :. * : : *. ::