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MTPQPTASSFAVLGLLGVQPWTAYELVAQSKRSLHWFWPRSERHLYAELKRLVERGHAEAHVEGGRRRRT RYTITPAGRAALQAWLGTEPAPPTLEIEGLVRVMLADQGNMDDLRAAVEATARQARTVRAEGLPFVAELL ATGGPFPQRLHLNERLVSFYSDFNNLLLRWCEETLADVETWQGTQDIGLTPSGRQRLVRAISEDP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2388 | - | - | 100% (205) | hypothetical protein MUL_2388 |
| M. ulcerans Agy99 | MUL_4945 | - | 6e-12 | 26.92% (182) | hypothetical protein MUL_4945 |
| M. ulcerans Agy99 | MUL_2728 | - | 1e-11 | 35.71% (98) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 3e-06 | 32.06% (131) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 6e-09 | 34.74% (95) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 3e-06 | 32.06% (131) | hypothetical protein Rv1176c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0082c | - | 9e-11 | 35.34% (116) | hypothetical protein MAB_0082c |
| M. marinum M | MMAR_1544 | - | 1e-116 | 98.54% (205) | hypothetical protein MMAR_1544 |
| M. avium 104 | MAV_0135 | - | 2e-13 | 31.00% (200) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6605 | - | 2e-10 | 35.04% (117) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0324 | - | 1e-09 | 29.55% (132) | transcriptional regulator, PadR family protein |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 4e-13 | 36.52% (115) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2388|M.ulcerans_Agy99 ---------MTPQPTASSFAVLGLLG-VQPWTAYELVAQSKRSLHWFWPR
MMAR_1544|M.marinum_M ---------MTPQPTASSFAVLGLLG-VQPWTAYELVAQSKRSLHWFWPR
MAB_0082c|M.abscessus_ATCC_199 --MAAISSPGEPNLAATSWTILGMLSYEEEVSGYDIKKWADWSISYFYWS
TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS
Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWTA
Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWTA
MAV_0135|M.avium_104 --------------MSLRDAVLAALL-EGESSGYDLAKDFDASVANFWPA
MSMEG_6605|M.smegmatis_MC2_155 --------------MALRDAVLAALL-EGESSGYDLAKSFDASVANFWTA
Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLA-QHPASGYDLLKKFEVSMANVWPG
Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLA-EGSASGYDLLKQFEKSMANVWPA
. : * * :.*:: . : .:
MUL_2388|M.ulcerans_Agy99 -SERHLYAELKRLVERGHAEAHVEGG--RRRRTRYTITPAGRAALQAWLG
MMAR_1544|M.marinum_M -SERHLYAELKRLVERGHAEAHVEGG--RRRRTRYTITPAGRAALQAWLG
MAB_0082c|M.abscessus_ATCC_199 PSFSQVYSELRKLEKIGYATSRVDHDNGARSRRLYKITPAGMAAMSQWAN
TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVTSRIEGS--TRSRRMYKITDAGLAAVTRWTN
Mb1209c|M.bovis_AF2122/97 -THQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWIA
Rv1176c|M.tuberculosis_H37Rv -THQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWIA
MAV_0135|M.avium_104 -TPQQLYRELDRLAGQGLIRARVVHQQRRPNKRMFSLTAAGRAAIRRFTA
MSMEG_6605|M.smegmatis_MC2_155 -TPQQLYRELERLAADGLIEARVVEQERRPNKRMFSLTDAGRAALREFTA
Mflv_1331|M.gilvum_PYR-GCK -TQSQLYSELNKLADDGLIEVTAIGARGR---KEYAITRPGRDELRRWVM
Mvan_5461|M.vanbaalenii_PYR-1 -TQSQLYSELNKLAAGGLIEVCAVGPRGR---KEYRITDAGRAELQRWVA
: ::* * : . : :: .* : :
MUL_2388|M.ulcerans_Agy99 TEPAPP----------TLEIEGLVRVMLADQGNMDDLRAAVEATARQART
MMAR_1544|M.marinum_M TEPAPP----------TLEIEGLLRVMLADQGNMDDLRAAVEATARQART
MAB_0082c|M.abscessus_ATCC_199 ETPAEPQ---------VLKHSVVLRVMQGHMTDPARLKEILERHIEYAEN
TH_0324|M.thermoresistible__bu EEPVEAP---------TLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADR
Mb1209c|M.bovis_AF2122/97 EPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVK
Rv1176c|M.tuberculosis_H37Rv EPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVK
MAV_0135|M.avium_104 TAPRPS----------VIRDELLIKVQAADAGDMRAVRDAIRERRDWATA
MSMEG_6605|M.smegmatis_MC2_155 KAPKPS----------TIRDELLIKVNAVDAGDAAAVRDAVTEQLRWATE
Mflv_1331|M.gilvum_PYR-GCK DFHDDP----------PQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAER
Mvan_5461|M.vanbaalenii_PYR-1 ERQDDP----------PVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADG
. ::: :
MUL_2388|M.ulcerans_Agy99 VRAEGLPFVAELLATGGPFPQRLHLNERLVSFYSDFNNLLLRWCEETLAD
MMAR_1544|M.marinum_M VRAEGLPLVAELLATGGPFPQRLHLNERLVSFYSDFNNLLLRWCEETLAD
MAB_0082c|M.abscessus_ATCC_199 MQRRAALDAAGAAAQPAWAYSRVAL-KWAERYYAAERDLAMMMIEDLAEA
TH_0324|M.thermoresistible__bu MQREAATEARHTAEQPAWSYARLAL-QWSERYYAAERDLALQLIKDLDVA
Mb1209c|M.bovis_AF2122/97 SLDTYRGIEKRTFADPS-----------ALDGAALHQYLVLRGGIRAEES
Rv1176c|M.tuberculosis_H37Rv SLDTYRGIEKRTFADPS-----------ALDGAALHQYLVLRGGIRAEES
MAV_0135|M.avium_104 KLARYQRLRARLLDGRSEEDY-------LARAERIGPYLTLIRGISFEED
MSMEG_6605|M.smegmatis_MC2_155 KLARYERMRIRMLAGRSEDEF-------VAGTDRIGPYLTLLRGISFEQE
Mflv_1331|M.gilvum_PYR-GCK DLARYEALRDAVPWNQSDD-------------DDFYGRAALEFGLRQAAM
Mvan_5461|M.vanbaalenii_PYR-1 EVRRLTELRESLTGGRAADP----------TDESFFGFAALDYGLRLNAM
. :
MUL_2388|M.ulcerans_Agy99 VETWQGTQDIGLTPSGRQRLVRAISEDP-------------
MMAR_1544|M.marinum_M VETWQGTQDIGLTPSGRQRLVRAISEHP-------------
MAB_0082c|M.abscessus_ATCC_199 AEEFDKAGPDGGTPRLVPGYWREVEKRVDAEKLSTQHDTAD
TH_0324|M.thermoresistible__bu DRIFTEAE-QSGLEWPVREYWYEVERRIAAEKDRE------
Mb1209c|M.bovis_AF2122/97 AIDWLDEVAEALQEKR-------------------------
Rv1176c|M.tuberculosis_H37Rv AIDWLDEVAEALQEKR-------------------------
MAV_0135|M.avium_104 NIRWAEHALAVIARRLPTTDADSDAGDSRLVGPATNG----
MSMEG_6605|M.smegmatis_MC2_155 NVRWAEQALDLLRRRMDP------GRQGRMLRSVRRT----
Mflv_1331|M.gilvum_PYR-GCK TADWARWVADGIRARQK------------------------
Mvan_5461|M.vanbaalenii_PYR-1 QAEWARSVIDRLDT---------------------------
: