For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VALRDAVLAALLEGESSGYDLAKSFDASVANFWTATPQQLYRELERLAADGLIEARVVEQERRPNKRMFS LTDAGRAALREFTAKAPKPSTIRDELLIKVNAVDAGDAAAVRDAVTEQLRWATEKLARYERMRIRMLAGR SEDEFVAGTDRIGPYLTLLRGISFEQENVRWAEQALDLLRRRMDPGRQGRMLRSVRRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6605 | - | - | 100% (198) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6226 | - | 5e-13 | 31.58% (190) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2868 | - | 3e-07 | 30.25% (119) | transcriptional regulator, PadR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 2e-21 | 31.77% (192) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 3e-16 | 32.97% (185) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 2e-21 | 31.77% (192) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 5e-05 | 33.33% (78) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_1326c | - | 1e-18 | 31.02% (187) | hypothetical protein MAB_1326c |
| M. marinum M | MMAR_0152 | - | 2e-70 | 71.04% (183) | hypothetical protein MMAR_0152 |
| M. avium 104 | MAV_0135 | - | 2e-75 | 74.32% (183) | transcriptional regulator, PadR family protein |
| M. thermoresistible (build 8) | TH_0324 | - | 6e-08 | 29.41% (119) | transcriptional regulator, PadR family protein |
| M. ulcerans Agy99 | MUL_4945 | - | 1e-69 | 70.49% (183) | hypothetical protein MUL_4945 |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 1e-18 | 34.07% (182) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLAQH-PASGYDLLKKFEVSMANVWP-
Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLAEG-SASGYDLLKQFEKSMANVWP-
MMAR_0152|M.marinum_M --------------MSLRDAVLAALLEG-ESSGYDLAKEFDASMANFWM-
MUL_4945|M.ulcerans_Agy99 --------------MSLRDAVLAALLEG-ESSGYDLAKEFDASMANFWM-
MAV_0135|M.avium_104 --------------MSLRDAVLAALLEG-ESSGYDLAKDFDASVANFWP-
MSMEG_6605|M.smegmatis_MC2_155 --------------MALRDAVLAALLEG-ESSGYDLAKSFDASVANFWT-
Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
MAB_1326c|M.abscessus_ATCC_199 --------------MALTHALLLSLAEQ-SGSGYELTNRFDRSIGYFYS-
MLBr_02691|M.leprae_Br4923 ---------------MLELAILGLLIES-PMHGYELRKRLTGLLGAFRA-
TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS
* * * **:: . : .
Mflv_1331|M.gilvum_PYR-GCK GTQSQLYSELNKLADDGLIEVTAIGA--RGR---KEYAITRPGRDELRRW
Mvan_5461|M.vanbaalenii_PYR-1 ATQSQLYSELNKLAAGGLIEVCAVGP--RGR---KEYRITDAGRAELQRW
MMAR_0152|M.marinum_M ATPQQLYRELERLTEQGLIQARVVHQ--ERRPNKRMHSLTESGRAAILQF
MUL_4945|M.ulcerans_Agy99 ATPQQLYRELERLTEQGLIQARVVHQ--ERRPNKRMHSLTESGRAAILQF
MAV_0135|M.avium_104 ATPQQLYRELDRLAGQGLIRARVVHQ--QRRPNKRMFSLTAAGRAAIRRF
MSMEG_6605|M.smegmatis_MC2_155 ATPQQLYRELERLAADGLIEARVVEQ--ERRPNKRMFSLTDAGRAALREF
Mb1209c|M.bovis_AF2122/97 ATHQQIYRTLRVMENNNWVRATTVLQ--HGRPDKKVYAISDSGRAELARW
Rv1176c|M.tuberculosis_H37Rv ATHQQIYRTLRVMENNNWVRATTVLQ--HGRPDKKVYAISDSGRAELARW
MAB_1326c|M.abscessus_ATCC_199 ATHQQIYRTLRRMEDDSWLHCQVVDQ--EGRPAKKVYTVAELGYRELSRW
MLBr_02691|M.leprae_Br4923 FSYGSLYPALRRMQADRLITGHVAPAGTPVRRARQVYQLTDAGRRRFSEL
TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVTSRIEGS----TRSRRMYKITDAGLAAVTRW
: .:* * : : : . :: * . .
Mflv_1331|M.gilvum_PYR-GCK VMD----------FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHA
Mvan_5461|M.vanbaalenii_PYR-1 VAE----------RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEA
MMAR_0152|M.marinum_M TSK----------PPKPAVIRDELLIKIQACDAGNIDAVREFVVELLQWA
MUL_4945|M.ulcerans_Agy99 TSK----------PPKPAVIRDELLIKIQACDAGNIDAVREFVVELLQWA
MAV_0135|M.avium_104 TAT----------APRPSVIRDELLIKVQAADAGDMRAVRDAIRERRDWA
MSMEG_6605|M.smegmatis_MC2_155 TAK----------APKPSTIRDELLIKVNAVDAGDAAAVRDAVTEQLRWA
Mb1209c|M.bovis_AF2122/97 IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
Rv1176c|M.tuberculosis_H37Rv IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
MAB_1326c|M.abscessus_ATCC_199 IAS----------SEGTD--MRDLALKVRAATYADSDVVIEQIRAQRNAH
MLBr_02691|M.leprae_Br4923 VTD----------TGPDNYTDNGFGVHLAFFNRTPAEARMRILEGRRRRV
TH_0324|M.thermoresistible__bu TNEE---------PVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYA
::: :
Mflv_1331|M.gilvum_PYR-GCK ERDLARYEALRDAVPWNQSDD------DDFYGRAALEFGLRQAAM-TADW
Mvan_5461|M.vanbaalenii_PYR-1 DGEVRRLTELRESLTGGRAADP---TDESFFGFAALDYGLRLNAM-QAEW
MMAR_0152|M.marinum_M TAKLERYERARRRMLDGRTEQEYLTQAERIGPYLTLLRGISFEQA-NIQW
MUL_4945|M.ulcerans_Agy99 AAKLERYERARRRMLDGRTEQEHLTQAERIGPYLTLLRGISFEQA-NIQW
MAV_0135|M.avium_104 TAKLARYQRLRARLLDGRSEEDYLARAERIGPYLTLIRGISFEED-NIRW
MSMEG_6605|M.smegmatis_MC2_155 TEKLARYERMRIRMLAGRSEDEFVAGTDRIGPYLTLLRGISFEQE-NVRW
Mb1209c|M.bovis_AF2122/97 VKSLDTYRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEES-AIDW
Rv1176c|M.tuberculosis_H37Rv VKSLDTYRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEES-AIDW
MAB_1326c|M.abscessus_ATCC_199 AAALEGYLHMQKRQFPAPD----QLSGAALHQYLVLRGGIRMEEG-FTDW
MLBr_02691|M.leprae_Br4923 E---ERREGLREAVTRASN-------SFDRYTRQLHQLGLESSER-EVKW
TH_0324|M.thermoresistible__bu DRMQREAATEARHTAEQPAWSYARLALQWSERYYAAERDLALQLIKDLDV
.:
Mflv_1331|M.gilvum_PYR-GCK ARWVADGIRARQK----------------------
Mvan_5461|M.vanbaalenii_PYR-1 ARSVIDRLDT-------------------------
MMAR_0152|M.marinum_M AEQTLKILDFRLATQTG------------------
MUL_4945|M.ulcerans_Agy99 AEQTLKILDFRLATQTG------------------
MAV_0135|M.avium_104 AEHALAVIARRLPTTDADSDAGDSRLVGPATNG--
MSMEG_6605|M.smegmatis_MC2_155 AEQALDLLRRRMDPGRQGRMLRSVRRT--------
Mb1209c|M.bovis_AF2122/97 LDEVAEALQEKR-----------------------
Rv1176c|M.tuberculosis_H37Rv LDEVAEALQEKR-----------------------
MAB_1326c|M.abscessus_ATCC_199 CDEMLSALSSSHVPARTDESEIDE-----------
MLBr_02691|M.leprae_Br4923 LNELIAAERALLGRVEQT-----------------
TH_0324|M.thermoresistible__bu ADRIFTEAEQSGLEWPVREYWYEVERRIAAEKDRE