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MSLRIAALGLLAEGSASGYDLLKQFEKSMANVWPATQSQLYSELNKLAAGGLIEVCAVGPRGRKEYRITD AGRAELQRWVAERQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGEVRRLTELRESLTGGRAAD PTDESFFGFAALDYGLRLNAMQAEWARSVIDRLDT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | - | 100% (175) | PadR-like family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2867 | - | 2e-08 | 32.09% (134) | PadR-like family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_6039 | - | 9e-06 | 24.14% (174) | PadR-like family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 7e-12 | 40.00% (85) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 1e-51 | 60.82% (171) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 7e-12 | 40.00% (85) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 9e-07 | 26.29% (175) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_0082c | - | 9e-09 | 30.81% (172) | hypothetical protein MAB_0082c |
| M. marinum M | MMAR_3454 | - | 2e-48 | 56.90% (174) | putative regulatory protein |
| M. avium 104 | MAV_0135 | - | 1e-17 | 36.36% (143) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6226 | - | 3e-61 | 68.57% (175) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_0324 | - | 5e-10 | 31.21% (173) | transcriptional regulator, PadR family protein |
| M. ulcerans Agy99 | MUL_2728 | - | 3e-46 | 55.75% (174) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLA-EGSASGYDLLKQFEKSMANVWP-
MSMEG_6226|M.smegmatis_MC2_155 --------------MSLRMAALGLLV-QQPGSGYDLLRRFEKSMANVWP-
Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLA-QHPASGYDLLKKFEVSMANVWP-
MMAR_3454|M.marinum_M --------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP-
MUL_2728|M.ulcerans_Agy99 --------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP-
MAB_0082c|M.abscessus_ATCC_199 --MAAISSPGEPNLAATSWTILGMLSYEEEVSGYDIKKWADWSISYFYWS
TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS
Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT-
Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT-
MAV_0135|M.avium_104 --------------MSLRDAVLAALL-EGESSGYDLAKDFDASVANFWP-
MLBr_02691|M.leprae_Br4923 ---------------MLELAILGLLI-ESPMHGYELRKRLTGLLGAFRA-
: * * **:: : : .
Mvan_5461|M.vanbaalenii_PYR-1 ATQSQLYSELNKLAAGGLIEV-----CAVGPRGRKEYRITDAGRAELQRW
MSMEG_6226|M.smegmatis_MC2_155 ATQSQLYGELNKLAAAGLIEV-----SAVGPRGRKEYRATDAGRAELLRW
Mflv_1331|M.gilvum_PYR-GCK GTQSQLYSELNKLADDGLIEV-----TAIGARGRKEYAITRPGRDELRRW
MMAR_3454|M.marinum_M ATQSQLYSELNKLAAAGLIKS-----SDLGPRGRKEYAITDAGRAELYRW
MUL_2728|M.ulcerans_Agy99 ATQSQLYSELNKLAAAGLIKS-----SDLGPRGRKEYAITDAGRAELYRW
MAB_0082c|M.abscessus_ATCC_199 PSFSQVYSELRKLEKIGYATSRVD--HDNGARSRRLYKITPAGMAAMSQW
TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVTSRIE--GS--TRSRRMYKITDAGLAAVTRW
Mb1209c|M.bovis_AF2122/97 ATHQQIYRTLRVMENNNWVRATTV--LQHGRPDKKVYAISDSGRAELARW
Rv1176c|M.tuberculosis_H37Rv ATHQQIYRTLRVMENNNWVRATTV--LQHGRPDKKVYAISDSGRAELARW
MAV_0135|M.avium_104 ATPQQLYRELDRLAGQGLIRARVV--HQQRRPNKRMFSLTAAGRAAIRRF
MLBr_02691|M.leprae_Br4923 FSYGSLYPALRRMQADRLITGHVAPAGTPVRRARQVYQLTDAGRRRFSEL
: .:* * : :: : : .* . .
Mvan_5461|M.vanbaalenii_PYR-1 VAE-RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGEVRRLTE
MSMEG_6226|M.smegmatis_MC2_155 ITN-PQDDPPERSAELLRVFLLGELPPEQAREHLVMLASHSDGEVERLRA
Mflv_1331|M.gilvum_PYR-GCK VMD-FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERDLARYEA
MMAR_3454|M.marinum_M MTS-PQQDPPVRNAALLRVFLLGQLDPSQARSYLESLLSLSEQEKTHYEQ
MUL_2728|M.ulcerans_Agy99 MTS-PQQDPPVRNAALLRVFLLGQLDPSQAGSYLESLLSLSEQEKTHYER
MAB_0082c|M.abscessus_ATCC_199 ANETPAEPQVLKHSVVLRVMQGHMTDPARLKEILERHIEYAEN-MQRRAA
TH_0324|M.thermoresistible__bu TNEEPVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADR-MQREAA
Mb1209c|M.bovis_AF2122/97 IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
Rv1176c|M.tuberculosis_H37Rv IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
MAV_0135|M.avium_104 TATAPRPS-VIRDELLIKVQAADAGDMRAVRDAIRERRDWATAKLARYQR
MLBr_02691|M.leprae_Br4923 VTDTGPDNYTDNGFGVHLAFFNRTPAEARMRILEGRRRRVEERREGLREA
. :
Mvan_5461|M.vanbaalenii_PYR-1 LRESLTGG--------RAADPTDESFFGFAALDYGLRLNAMQAEWARSVI
MSMEG_6226|M.smegmatis_MC2_155 LEAAID----------WAGEP-GADVFSHAALDYGLRMHTMQAQWARDVI
Mflv_1331|M.gilvum_PYR-GCK LRDAVP----------WNQSD-DDDFYGRAALEFGLRQAAMTADWARWVA
MMAR_3454|M.marinum_M IRDAYD----------WAEDD--DSFFARAALEQGLRWAQQEIEWAKWVI
MUL_2728|M.ulcerans_Agy99 IRYAYD----------WAEDD--DSFFARAAPEQGLRWAQQEIEWAKWVI
MAB_0082c|M.abscessus_ATCC_199 LDAAGA-----------AAQP--AWAYSRVALKWAERYYAAERDLAMMMI
TH_0324|M.thermoresistible__bu TEARHT-----------AEQP--AWSYARLALQWSERYYAAERDLALQLI
Mb1209c|M.bovis_AF2122/97 VKSLDTYRGIEKRTFADPSALDGAALHQYLVLRGGIRAEESAIDWLDEVA
Rv1176c|M.tuberculosis_H37Rv VKSLDTYRGIEKRTFADPSALDGAALHQYLVLRGGIRAEESAIDWLDEVA
MAV_0135|M.avium_104 LRARLLDGRSE-----EDYLARAERIGPYLTLIRGISFEEDNIRWAEHAL
MLBr_02691|M.leprae_Br4923 VTRASN----------------SFDRYTRQLHQLGLESSEREVKWLNELI
.
Mvan_5461|M.vanbaalenii_PYR-1 DRLDT------------------------------------------
MSMEG_6226|M.smegmatis_MC2_155 ARMDTNR----------------------------------------
Mflv_1331|M.gilvum_PYR-GCK DGIRARQK---------------------------------------
MMAR_3454|M.marinum_M AGLDQRSGVAPAGQG--------------------------------
MUL_2728|M.ulcerans_Agy99 AGLDQRSGVAPAGQG--------------------------------
MAB_0082c|M.abscessus_ATCC_199 EDLAEAAEEFDKAGPDGGTPRLVPGYWREVEKRVDAEKLSTQHDTAD
TH_0324|M.thermoresistible__bu KDLDVADRIFTEAE-QSGLEWPVREYWYEVERRIAAEKDRE------
Mb1209c|M.bovis_AF2122/97 EALQEKR----------------------------------------
Rv1176c|M.tuberculosis_H37Rv EALQEKR----------------------------------------
MAV_0135|M.avium_104 AVIARRLPTTDADSDAGDSRLVGPATNG-------------------
MLBr_02691|M.leprae_Br4923 AAERALLGRVEQT----------------------------------