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SIVECHRYYSSMSLRMAALGLLAQHPASGYDLLKKFEVSMANVWPGTQSQLYSELNKLADDGLIEVTAIG ARGRKEYAITRPGRDELRRWVMDFHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERDLARYEAL RDAVPWNQSDDDDFYGRAALEFGLRQAAMTADWARWVADGIRARQK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1331 | - | - | 100% (187) | PadR-like family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4568 | - | 7e-10 | 36.20% (163) | PadR-like family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0868 | - | 5e-07 | 25.90% (166) | PadR-like family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 6e-12 | 28.57% (189) | hypothetical protein Mb1209c |
| M. tuberculosis H37Rv | Rv1176c | - | 6e-12 | 28.57% (189) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 5e-07 | 26.67% (165) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_1326c | - | 2e-07 | 31.33% (83) | hypothetical protein MAB_1326c |
| M. marinum M | MMAR_3454 | - | 1e-49 | 56.07% (173) | putative regulatory protein |
| M. avium 104 | MAV_0135 | - | 5e-15 | 33.33% (144) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6226 | - | 8e-51 | 57.93% (164) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_1310 | - | 5e-07 | 24.70% (166) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2728 | - | 8e-49 | 55.49% (173) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 2e-51 | 60.82% (171) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6226|M.smegmatis_MC2_155 ------------MSLRMAALGLLVQQPGSGYDLLRRFEKSMANVWPATQS
Mvan_5461|M.vanbaalenii_PYR-1 ------------MSLRIAALGLLAEGSASGYDLLKQFEKSMANVWPATQS
MMAR_3454|M.marinum_M ------------MSLRHAALGLLSQEPGSGYDLLKRFQLSMNNVWPATQS
MUL_2728|M.ulcerans_Agy99 ------------MSLRHAALGLLSQEPGSGYDLLKRFQLSMNNVWPATQS
Mflv_1331|M.gilvum_PYR-GCK MSIVECHRYYSSMSLRMAALGLLAQHPASGYDLLKKFEVSMANVWPGTQS
MLBr_02691|M.leprae_Br4923 -------------MLELAILGLLIESPMHGYELRKRLTGLLGAFRAFSYG
TH_1310|M.thermoresistible__bu ----------VIRLLELAILGLLLESPMHGYELRKRLTGLLGAFRAFSYG
Mb1209c|M.bovis_AF2122/97 ------------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQ
Rv1176c|M.tuberculosis_H37Rv ------------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQ
MAB_1326c|M.abscessus_ATCC_199 ------------MALTHALLLSLAEQSGSGYELTNRFDRSIGYFYSATHQ
MAV_0135|M.avium_104 ------------MSLRDAVLAALLEGESSGYDLAKDFDASVANFWPATPQ
* * * * : **:* . : : . . :
MSMEG_6226|M.smegmatis_MC2_155 QLYGELNKLAAAGLIEVSAVG------PRGRKEYRATDAGRAELLRWITN
Mvan_5461|M.vanbaalenii_PYR-1 QLYSELNKLAAGGLIEVCAVG------PRGRKEYRITDAGRAELQRWVAE
MMAR_3454|M.marinum_M QLYSELNKLAAAGLIKSSDLG------PRGRKEYAITDAGRAELYRWMTS
MUL_2728|M.ulcerans_Agy99 QLYSELNKLAAAGLIKSSDLG------PRGRKEYAITDAGRAELYRWMTS
Mflv_1331|M.gilvum_PYR-GCK QLYSELNKLADDGLIEVTAIG------ARGRKEYAITRPGRDELRRWVMD
MLBr_02691|M.leprae_Br4923 SLYPALRRMQADRLITGHVAPAGTP-VRRARQVYQLTDAGRRRFSELVTD
TH_1310|M.thermoresistible__bu SLYPALRRMQADGLIVEDPAPDGTPKVRRARRVYRLTEAGKQRFTELVAD
Mb1209c|M.bovis_AF2122/97 QIYRTLRVMENNNWVRATTVLQHG---RPDKKVYAISDSGRAELARWIAE
Rv1176c|M.tuberculosis_H37Rv QIYRTLRVMENNNWVRATTVLQHG---RPDKKVYAISDSGRAELARWIAE
MAB_1326c|M.abscessus_ATCC_199 QIYRTLRRMEDDSWLHCQVVDQEG---RPAKKVYTVAELGYRELSRWIAS
MAV_0135|M.avium_104 QLYRELDRLAGQGLIRARVVHQQR---RPNKRMFSLTAAGRAAIRRFTAT
.:* * : : :: : : * : .
MSMEG_6226|M.smegmatis_MC2_155 ----------PQDDPPERSAELLRVFLLGELPPEQAREHLVMLASHSDGE
Mvan_5461|M.vanbaalenii_PYR-1 ----------RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGE
MMAR_3454|M.marinum_M ----------PQQDPPVRNAALLRVFLLGQLDPSQARSYLESLLSLSEQE
MUL_2728|M.ulcerans_Agy99 ----------PQQDPPVRNAALLRVFLLGQLDPSQAGSYLESLLSLSEQE
Mflv_1331|M.gilvum_PYR-GCK ----------FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERD
MLBr_02691|M.leprae_Br4923 ----------TGPDNYTDNGFGVHLAFFNRTP---AEARMRILEGRRRRV
TH_1310|M.thermoresistible__bu ----------TGPQNYSDDGFGVHLAFFNRTP---AEARMRILEGRRRQV
Mb1209c|M.bovis_AF2122/97 PLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKS
Rv1176c|M.tuberculosis_H37Rv PLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKS
MAB_1326c|M.abscessus_ATCC_199 ----------SEGTD--MRDLALKVRAATYADSDVVIEQIRAQRNAHAAA
MAV_0135|M.avium_104 ----------APRPSVIRDELLIKVQAADAGDMRAVRDAIRERRDWATAK
::: :
MSMEG_6226|M.smegmatis_MC2_155 VERLRALEAAID--WAGEP------GADVFSHAALDYGLRMHTMQAQWAR
Mvan_5461|M.vanbaalenii_PYR-1 VRRLTELRESLTGGRAADPT-----DESFFGFAALDYGLRLNAMQAEWAR
MMAR_3454|M.marinum_M KTHYEQIRDAYD--WAEDD-------DSFFARAALEQGLRWAQQEIEWAK
MUL_2728|M.ulcerans_Agy99 KTHYERIRYAYD--WAEDD-------DSFFARAAPEQGLRWAQQEIEWAK
Mflv_1331|M.gilvum_PYR-GCK LARYEALRDAVP--WNQSD------DDDFYGRAALEFGLRQAAMTADWAR
MLBr_02691|M.leprae_Br4923 EERREGLREAVT--RASNS-------FDRYTRQLHQLGLESSEREVKWLN
TH_1310|M.thermoresistible__bu EERREGLREAIA--RASNS-------FDRYTRQLHQLGLESSEREVNWLN
Mb1209c|M.bovis_AF2122/97 LDTYRGIEKRTFA--DPS----ALDGAALHQYLVLRGGIRAEESAIDWLD
Rv1176c|M.tuberculosis_H37Rv LDTYRGIEKRTFA--DPS----ALDGAALHQYLVLRGGIRAEESAIDWLD
MAB_1326c|M.abscessus_ATCC_199 LEGYLHMQKRQFP--APD----QLSGAALHQYLVLRGGIRMEEGFTDWCD
MAV_0135|M.avium_104 LARYQRLRARLLD--GRSEEDYLARAERIGPYLTLIRGISFEEDNIRWAE
:. . *: *
MSMEG_6226|M.smegmatis_MC2_155 DVIARMDTNR---------------------
Mvan_5461|M.vanbaalenii_PYR-1 SVIDRLDT-----------------------
MMAR_3454|M.marinum_M WVIAGLDQRSGVAPAGQG-------------
MUL_2728|M.ulcerans_Agy99 WVIAGLDQRSGVAPAGQG-------------
Mflv_1331|M.gilvum_PYR-GCK WVADGIRARQK--------------------
MLBr_02691|M.leprae_Br4923 ELIAAERALLGRVEQT---------------
TH_1310|M.thermoresistible__bu DLIAAERMAQGRAEQP---------------
Mb1209c|M.bovis_AF2122/97 EVAEALQEKR---------------------
Rv1176c|M.tuberculosis_H37Rv EVAEALQEKR---------------------
MAB_1326c|M.abscessus_ATCC_199 EMLSALSSSHVPARTDESEIDE---------
MAV_0135|M.avium_104 HALAVIARRLPTTDADSDAGDSRLVGPATNG