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SLRDAVLAALLEGESSGYDLAKDFDASVANFWPATPQQLYRELDRLAGQGLIRARVVHQQRRPNKRMFSL TAAGRAAIRRFTATAPRPSVIRDELLIKVQAADAGDMRAVRDAIRERRDWATAKLARYQRLRARLLDGRS EEDYLARAERIGPYLTLIRGISFEEDNIRWAEHALAVIARRLPTTDADSDAGDSRLVGPATNG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0135 | - | - | 100% (204) | transcriptional regulator, PadR family protein |
| M. avium 104 | MAV_3044 | - | 5e-11 | 31.30% (115) | transcriptional regulator, PadR family protein |
| M. avium 104 | MAV_5256 | - | 5e-06 | 27.09% (203) | hypothetical protein MAV_5256 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 2e-19 | 31.77% (192) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 7e-15 | 33.33% (144) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 2e-19 | 31.77% (192) | hypothetical protein Rv1176c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1326c | - | 5e-18 | 31.67% (180) | hypothetical protein MAB_1326c |
| M. marinum M | MMAR_0152 | - | 1e-72 | 71.35% (185) | hypothetical protein MMAR_0152 |
| M. smegmatis MC2 155 | MSMEG_6605 | - | 2e-75 | 74.32% (183) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0324 | - | 1e-06 | 37.35% (83) | transcriptional regulator, PadR family protein |
| M. ulcerans Agy99 | MUL_4945 | - | 1e-71 | 70.27% (185) | hypothetical protein MUL_4945 |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 2e-17 | 36.36% (143) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLAQH-PASGYDLLKKFEVSMANVWP-
Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLAEG-SASGYDLLKQFEKSMANVWP-
Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
MAB_1326c|M.abscessus_ATCC_199 --------------MALTHALLLSLAEQ-SGSGYELTNRFDRSIGYFYS-
MMAR_0152|M.marinum_M --------------MSLRDAVLAALLEG-ESSGYDLAKEFDASMANFWM-
MUL_4945|M.ulcerans_Agy99 --------------MSLRDAVLAALLEG-ESSGYDLAKEFDASMANFWM-
MAV_0135|M.avium_104 --------------MSLRDAVLAALLEG-ESSGYDLAKDFDASVANFWP-
MSMEG_6605|M.smegmatis_MC2_155 --------------MALRDAVLAALLEG-ESSGYDLAKSFDASVANFWT-
TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS
. * * * ***:: . : : .:
Mflv_1331|M.gilvum_PYR-GCK GTQSQLYSELNKLADDGLIEVTAIGARGR---KEYAITRPGRDELRRWVM
Mvan_5461|M.vanbaalenii_PYR-1 ATQSQLYSELNKLAAGGLIEVCAVGPRGR---KEYRITDAGRAELQRWVA
Mb1209c|M.bovis_AF2122/97 ATHQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWIA
Rv1176c|M.tuberculosis_H37Rv ATHQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWIA
MAB_1326c|M.abscessus_ATCC_199 ATHQQIYRTLRRMEDDSWLHCQVVDQEGRPAKKVYTVAELGYRELSRWIA
MMAR_0152|M.marinum_M ATPQQLYRELERLTEQGLIQARVVHQERRPNKRMHSLTESGRAAILQFTS
MUL_4945|M.ulcerans_Agy99 ATPQQLYRELERLTEQGLIQARVVHQERRPNKRMHSLTESGRAAILQFTS
MAV_0135|M.avium_104 ATPQQLYRELDRLAGQGLIRARVVHQQRRPNKRMFSLTAAGRAAIRRFTA
MSMEG_6605|M.smegmatis_MC2_155 ATPQQLYRELERLAADGLIEARVVEQERRPNKRMFSLTDAGRAALREFTA
TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVTSRIEGSTRS--RRMYKITDAGLAAVTRWTN
: .*:* * : . : : . :: * : .:
Mflv_1331|M.gilvum_PYR-GCK D----------FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAER
Mvan_5461|M.vanbaalenii_PYR-1 E----------RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADG
Mb1209c|M.bovis_AF2122/97 EPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVK
Rv1176c|M.tuberculosis_H37Rv EPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVK
MAB_1326c|M.abscessus_ATCC_199 S----------SEGTD--MRDLALKVRAATYADSDVVIEQIRAQRNAHAA
MMAR_0152|M.marinum_M K----------PPKPAVIRDELLIKIQACDAGNIDAVREFVVELLQWATA
MUL_4945|M.ulcerans_Agy99 K----------PPKPAVIRDELLIKIQACDAGNIDAVREFVVELLQWAAA
MAV_0135|M.avium_104 T----------APRPSVIRDELLIKVQAADAGDMRAVRDAIRERRDWATA
MSMEG_6605|M.smegmatis_MC2_155 K----------APKPSTIRDELLIKVNAVDAGDAAAVRDAVTEQLRWATE
TH_0324|M.thermoresistible__bu EE---------PVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADR
::: :
Mflv_1331|M.gilvum_PYR-GCK DLARYEALRDAVPWNQSDD------DDFYGRAALEFGLRQAAM-TADWAR
Mvan_5461|M.vanbaalenii_PYR-1 EVRRLTELRESLTGGRAADP---TDESFFGFAALDYGLRLNAM-QAEWAR
Mb1209c|M.bovis_AF2122/97 SLDTYRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEES-AIDWLD
Rv1176c|M.tuberculosis_H37Rv SLDTYRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEES-AIDWLD
MAB_1326c|M.abscessus_ATCC_199 ALEGYLHMQKRQFPAPD----QLSGAALHQYLVLRGGIRMEEG-FTDWCD
MMAR_0152|M.marinum_M KLERYERARRRMLDGRTEQEYLTQAERIGPYLTLLRGISFEQA-NIQWAE
MUL_4945|M.ulcerans_Agy99 KLERYERARRRMLDGRTEQEHLTQAERIGPYLTLLRGISFEQA-NIQWAE
MAV_0135|M.avium_104 KLARYQRLRARLLDGRSEEDYLARAERIGPYLTLIRGISFEED-NIRWAE
MSMEG_6605|M.smegmatis_MC2_155 KLARYERMRIRMLAGRSEDEFVAGTDRIGPYLTLLRGISFEQE-NVRWAE
TH_0324|M.thermoresistible__bu MQREAATEARHTAEQPAWSYARLALQWSERYYAAERDLALQLIKDLDVAD
. .:
Mflv_1331|M.gilvum_PYR-GCK WVADGIRARQK----------------------
Mvan_5461|M.vanbaalenii_PYR-1 SVIDRLDT-------------------------
Mb1209c|M.bovis_AF2122/97 EVAEALQEKR-----------------------
Rv1176c|M.tuberculosis_H37Rv EVAEALQEKR-----------------------
MAB_1326c|M.abscessus_ATCC_199 EMLSALSSSHVPARTDESEIDE-----------
MMAR_0152|M.marinum_M QTLKILDFRLATQTG------------------
MUL_4945|M.ulcerans_Agy99 QTLKILDFRLATQTG------------------
MAV_0135|M.avium_104 HALAVIARRLPTTDADSDAGDSRLVGPATNG--
MSMEG_6605|M.smegmatis_MC2_155 QALDLLRRRMDPGRQGRMLRSVRRT--------
TH_0324|M.thermoresistible__bu RIFTEAEQSGLEWPVREYWYEVERRIAAEKDRE