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SLRHAALGLLSQEPGSGYDLLKRFQLSMNNVWPATQSQLYSELNKLAAAGLIKSSDLGPRGRKEYAITDA GRAELYRWMTSPQQDPPVRNAALLRVFLLGQLDPSQAGSYLESLLSLSEQEKTHYERIRYAYDWAEDDDS FFARAAPEQGLRWAQQEIEWAKWVIAGLDQRSGVAPAGQG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_2728 | - | - | 100% (181) | putative regulatory protein |
M. ulcerans Agy99 | MUL_4945 | - | 2e-15 | 28.02% (182) | hypothetical protein MUL_4945 |
M. ulcerans Agy99 | MUL_1024 | - | 3e-13 | 30.89% (191) | hypothetical protein MUL_1024 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1209c | - | 1e-12 | 28.72% (188) | hypothetical protein Mb1209c |
M. gilvum PYR-GCK | Mflv_1331 | - | 1e-48 | 55.49% (173) | PadR-like family transcriptional regulator |
M. tuberculosis H37Rv | Rv1176c | - | 1e-12 | 28.72% (188) | hypothetical protein Rv1176c |
M. leprae Br4923 | MLBr_02691 | - | 2e-07 | 25.73% (171) | hypothetical protein MLBr_02691 |
M. abscessus ATCC 19977 | MAB_0082c | - | 2e-10 | 36.13% (119) | hypothetical protein MAB_0082c |
M. marinum M | MMAR_3454 | - | 3e-99 | 97.79% (181) | putative regulatory protein |
M. avium 104 | MAV_0135 | - | 7e-17 | 29.12% (182) | transcriptional regulator, PadR family protein |
M. smegmatis MC2 155 | MSMEG_6226 | - | 4e-52 | 61.40% (171) | transcriptional regulator |
M. thermoresistible (build 8) | TH_0324 | - | 6e-09 | 30.77% (169) | transcriptional regulator, PadR family protein |
M. vanbaalenii PYR-1 | Mvan_5461 | - | 4e-46 | 55.75% (174) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment MUL_2728|M.ulcerans_Agy99 --------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP- MMAR_3454|M.marinum_M --------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP- MSMEG_6226|M.smegmatis_MC2_155 --------------MSLRMAALGLLV-QQPGSGYDLLRRFEKSMANVWP- Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLA-EGSASGYDLLKQFEKSMANVWP- Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLA-QHPASGYDLLKKFEVSMANVWP- MAB_0082c|M.abscessus_ATCC_199 --MAAISSPGEPNLAATSWTILGMLSYEEEVSGYDIKKWADWSISYFYWS TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT- Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT- MAV_0135|M.avium_104 --------------MSLRDAVLAALL-EGESSGYDLAKDFDASVANFWP- MLBr_02691|M.leprae_Br4923 ---------------MLELAILGLLI-ESPMHGYELRKRLTGLLGAFRA- : * * **:: : : . MUL_2728|M.ulcerans_Agy99 ATQSQLYSELNKLAAAGLIKS-----SDLGPRGRKEYAITDAGRAELYRW MMAR_3454|M.marinum_M ATQSQLYSELNKLAAAGLIKS-----SDLGPRGRKEYAITDAGRAELYRW MSMEG_6226|M.smegmatis_MC2_155 ATQSQLYGELNKLAAAGLIEV-----SAVGPRGRKEYRATDAGRAELLRW Mvan_5461|M.vanbaalenii_PYR-1 ATQSQLYSELNKLAAGGLIEV-----CAVGPRGRKEYRITDAGRAELQRW Mflv_1331|M.gilvum_PYR-GCK GTQSQLYSELNKLADDGLIEV-----TAIGARGRKEYAITRPGRDELRRW MAB_0082c|M.abscessus_ATCC_199 PSFSQVYSELRKLEKIGYATSRVD--HDNGARSRRLYKITPAGMAAMSQW TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVTSRIE--GS--TRSRRMYKITDAGLAAVTRW Mb1209c|M.bovis_AF2122/97 ATHQQIYRTLRVMENNNWVRATTV--LQHGRPDKKVYAISDSGRAELARW Rv1176c|M.tuberculosis_H37Rv ATHQQIYRTLRVMENNNWVRATTV--LQHGRPDKKVYAISDSGRAELARW MAV_0135|M.avium_104 ATPQQLYRELDRLAGQGLIRARVV--HQQRRPNKRMFSLTAAGRAAIRRF MLBr_02691|M.leprae_Br4923 FSYGSLYPALRRMQADRLITGHVAPAGTPVRRARQVYQLTDAGRRRFSEL : .:* * : :: : : .* . . MUL_2728|M.ulcerans_Agy99 MTS-PQQDPPVRNAALLRVFLLGQLDPSQAGSYLESLLSLSEQEKTHYER MMAR_3454|M.marinum_M MTS-PQQDPPVRNAALLRVFLLGQLDPSQARSYLESLLSLSEQEKTHYEQ MSMEG_6226|M.smegmatis_MC2_155 ITN-PQDDPPERSAELLRVFLLGELPPEQAREHLVMLASHSDGEVERLRA Mvan_5461|M.vanbaalenii_PYR-1 VAE-RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGEVRRLTE Mflv_1331|M.gilvum_PYR-GCK VMD-FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERDLARYEA MAB_0082c|M.abscessus_ATCC_199 ANETPAEPQVLKHSVVLRVMQGHMTDPARLKEILERHIEYAEN-MQRRAA TH_0324|M.thermoresistible__bu TNEEPVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADR-MQREAA Mb1209c|M.bovis_AF2122/97 IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER Rv1176c|M.tuberculosis_H37Rv IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER MAV_0135|M.avium_104 TATAPRPS-VIRDELLIKVQAADAGDMRAVRDAIRERRDWATAKLARYQR MLBr_02691|M.leprae_Br4923 VTDTGPDNYTDNGFGVHLAFFNRTPAEARMRILEGRRRRVEERREGLREA . : MUL_2728|M.ulcerans_Agy99 IRYAYD----------WAEDD--DSFFARAAPEQGLRWAQQEIEWAKWVI MMAR_3454|M.marinum_M IRDAYD----------WAEDD--DSFFARAALEQGLRWAQQEIEWAKWVI MSMEG_6226|M.smegmatis_MC2_155 LEAAID----------WAGEP-GADVFSHAALDYGLRMHTMQAQWARDVI Mvan_5461|M.vanbaalenii_PYR-1 LRESLTGG--------RAADPTDESFFGFAALDYGLRLNAMQAEWARSVI Mflv_1331|M.gilvum_PYR-GCK LRDAVP----------WNQSD-DDDFYGRAALEFGLRQAAMTADWARWVA MAB_0082c|M.abscessus_ATCC_199 LDAAGA-----------AAQP--AWAYSRVALKWAERYYAAERDLAMMMI TH_0324|M.thermoresistible__bu TEARHT-----------AEQP--AWSYARLALQWSERYYAAERDLALQLI Mb1209c|M.bovis_AF2122/97 VKSLDTYRGIEKRTFADPSALDGAALHQYLVLRGGIRAEESAIDWLDEVA Rv1176c|M.tuberculosis_H37Rv VKSLDTYRGIEKRTFADPSALDGAALHQYLVLRGGIRAEESAIDWLDEVA MAV_0135|M.avium_104 LRARLLDGRSE-----EDYLARAERIGPYLTLIRGISFEEDNIRWAEHAL MLBr_02691|M.leprae_Br4923 VTRASN----------------SFDRYTRQLHQLGLESSEREVKWLNELI . MUL_2728|M.ulcerans_Agy99 AGLDQRSGVAPAGQG-------------------------------- MMAR_3454|M.marinum_M AGLDQRSGVAPAGQG-------------------------------- MSMEG_6226|M.smegmatis_MC2_155 ARMDTNR---------------------------------------- Mvan_5461|M.vanbaalenii_PYR-1 DRLDT------------------------------------------ Mflv_1331|M.gilvum_PYR-GCK DGIRARQK--------------------------------------- MAB_0082c|M.abscessus_ATCC_199 EDLAEAAEEFDKAGPDGGTPRLVPGYWREVEKRVDAEKLSTQHDTAD TH_0324|M.thermoresistible__bu KDLDVADRIFTEAE-QSGLEWPVREYWYEVERRIAAEKDRE------ Mb1209c|M.bovis_AF2122/97 EALQEKR---------------------------------------- Rv1176c|M.tuberculosis_H37Rv EALQEKR---------------------------------------- MAV_0135|M.avium_104 AVIARRLPTTDADSDAGDSRLVGPATNG------------------- MLBr_02691|M.leprae_Br4923 AAERALLGRVEQT----------------------------------