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GKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGFSANTGQDTAGEVFGLAYQDAAESLVKAAG AGINALRHNGAKIQLSASNYSAAEAASTLGGGAGVLPAPSEPAQFTAPGAPGTLGSGVLAPALWSVVEAF VGDLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNSPKSVVAGQDIPEGVQIQQVLSAIGSDLAGVGAQC RKLAGALDDFADEVADTQDAIRDLLDRFGSVSGLWNQVVAIFEGDALDEIKEIAEDIRAVLSNLGRQARA QQQLMQQGMQAIDGLVVGMQRYVRGQLTQLLGQDVGNPVATVFDTYTNTQEGVFKAAVGMVEGIEQLNPQ RFLIDPQGAAETWKAMTKTGLINHLLNPEEAVAADKEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVP GAGGAGAGAKGAAGAARAAEVGGEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKTGRGLTEDLANLG GDLPKADPPVGGRPVALPPPKPAGAPIEPTPRPVESVPPGKPALEAPSGAPGSVVPGRSEPAFGPHDPAS APVAGSHPAATAVTPGERLSPVTPHVGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRP AELSAPHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGTAHGTADGGDAHGDDVS GHGLSAEKRDEIIAMRKGSRPDPSEYLSPEYIQGHLDRFTGGATRFMPESNLDKYGIAQRDGTSFVMPKS EADAMIAGTGGDLRLMEEELGLPEGFLDSNQIVRIDIEDPRQFNLRIPSGNEAGANEQWIPGGLLPTGAS EAVVDGGKVPQGDYTVTDVFEEK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2318 | - | - | 100% (864) | hypothetical protein MUL_2318 |
| M. ulcerans Agy99 | MUL_2122 | infB | 3e-13 | 31.23% (285) | translation initiation factor IF-2 |
| M. ulcerans Agy99 | MUL_0579 | iniB | 3e-11 | 28.37% (289) | membrane protein, IniB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3933c | - | 5e-66 | 31.09% (727) | hypothetical protein Mb3933c |
| M. gilvum PYR-GCK | Mflv_3843 | - | 4e-20 | 37.28% (287) | hypothetical protein Mflv_3843 |
| M. tuberculosis H37Rv | Rv3903c | - | 5e-66 | 31.09% (727) | hypothetical protein Rv3903c |
| M. leprae Br4923 | MLBr_02591 | mce1C | 4e-06 | 28.02% (207) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_3131c | - | 7e-13 | 30.77% (208) | translation initiation factor IF-2 (InfB) |
| M. marinum M | MMAR_3072 | - | 0.0 | 98.25% (858) | hypothetical protein MMAR_3072 |
| M. avium 104 | MAV_2415 | - | 1e-164 | 43.02% (853) | hypothetical protein MAV_2415 |
| M. smegmatis MC2 155 | MSMEG_1870 | - | 7e-61 | 28.88% (703) | hypothetical protein MSMEG_1870 |
| M. thermoresistible (build 8) | TH_3868 | - | 5e-28 | 27.63% (333) | PUTATIVE putative conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_2314 | infB | 1e-15 | 33.20% (250) | translation initiation factor IF-2 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2318|M.ulcerans_Agy99 --------MGKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGF
MMAR_3072|M.marinum_M --------------MAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGF
MAV_2415|M.avium_104 --------------MAPLAVDPEAMYAAGSAVAAIGDSLAANLTILTAGV
Mb3933c|M.bovis_AF2122/97 --------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAAL
Rv3903c|M.tuberculosis_H37Rv --------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAAL
MSMEG_1870|M.smegmatis_MC2_155 --MPSNSGGGGGVSGIRIEVDPQVLIRAGESMLSLGNQLDMLMGALGPML
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 -----------MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTV
Mvan_2314|M.vanbaalenii_PYR-1 -----------MAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTV
MLBr_02591|M.leprae_Br4923 ------------------------MRTLELPNRLRSGLIGVLVVLLIIGV
Mflv_3843|M.gilvum_PYR-GCK MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR
MUL_2318|M.ulcerans_Agy99 S---ANTGQDTAGEVFGLAYQDAAES------LVKAAGAGINALRHNGAK
MMAR_3072|M.marinum_M S---ANTGQDAAGEVFGLAYQDAAES------LVKAAGAGINALRHNGAK
MAV_2415|M.avium_104 S---AHTGVDRAGEVFGLGYQDSAES------MLKAAAGVVNACRKCGAL
Mb3933c|M.bovis_AF2122/97 AGCAGMAGDDPAGAVFGRSYDGSAAA------LVQAMSVARNGLCNLGDG
Rv3903c|M.tuberculosis_H37Rv AGCAGMAGDDPAGAVFGRSYDGSAAA------LVQAMSVARNGLCNLGDG
MSMEG_1870|M.smegmatis_MC2_155 SSG-IASGIDLAGLAMALDYGDLTQK------FSNTLANGANTFKTVGLR
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 EAPVARRLRESFGGG--DKPAPAASN----GAAAEAAAPPKKAGPKPGAP
Mvan_2314|M.vanbaalenii_PYR-1 EAPVARRLRESYGGSKSDKTKAAPSGNGAAGATVKPSAPQSRPGPKPGP-
MLBr_02591|M.leprae_Br4923 GQSFTSVPILFARPSYYGQFTDTGGLN-------------------KGDK
Mflv_3843|M.gilvum_PYR-GCK PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV
MUL_2318|M.ulcerans_Agy99 IQLSASNYSAAEAASTLGGGAGVLPAP-SEPAQFTAPGAPGTLGSGVLAP
MMAR_3072|M.marinum_M IQLSASNYSAAEAASTLGGGAGVLPAP-SEPAQFTAPGAPGTLGSGVLAP
MAV_2415|M.avium_104 IQQGASNYSAAEAASTLGGGSGALPAP-SAPADLAAPGPPGTWGKGEPPP
Mb3933c|M.bovis_AF2122/97 VRMSAHNYSLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAP
Rv3903c|M.tuberculosis_H37Rv VRMSAHNYSLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAP
MSMEG_1870|M.smegmatis_MC2_155 LQASGHNYANADAVSTIGGGAPTGGVKGKFDETKPVDARDSPSLSVVPPP
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 KPAPKKVAEPVVEAPVAPEPPAAPAAPAAPAPKPSPAARPAAAEAAAPAP
Mvan_2314|M.vanbaalenii_PYR-1 -PVAQQPAAPAAPPAAPPAPPTPAAAPPSPAPAAPAAATPAEPAAPSARP
MLBr_02591|M.leprae_Br4923 VRIAGMDVGKVEALKIDG--------------------------------
Mflv_3843|M.gilvum_PYR-GCK TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP
MUL_2318|M.ulcerans_Agy99 ALWSVVEAFVG------------DLWPNGDVAGLHAAAGHWRDFAAALNG
MMAR_3072|M.marinum_M ALWSVVEAFVG------------DLWPNGDVAGLHAAAGHWRDFAAALNG
MAV_2415|M.avium_104 LLWAVIQALVS------------EVWPDGDEAGLHAAASRWHGFAAAMNG
Mb3933c|M.bovis_AF2122/97 KGWGWVAPYIG------------MIWPNGDSTKLRAAAVAWRSAGTQFAL
Rv3903c|M.tuberculosis_H37Rv KGWGWVAPYIG------------MIWPNGDSTKLRAAAVAWRSAGTQFAL
MSMEG_1870|M.smegmatis_MC2_155 PAWYLVGSFLGP-----------TAWPSGNPAMLRLTAAQWENLATGFSA
TH_3868|M.thermoresistible__bu --------------------------------MLRLTVAQWRNFAHGFAV
MAB_3131c|M.abscessus_ATCC_199 APAPAPRPGATP-----------GPKPGAP----RVPRVGNNPFSSAQPA
Mvan_2314|M.vanbaalenii_PYR-1 GPTPGPRPGPS------------APKPGAPKPAARTPRVGNNPFSSQQPV
MLBr_02591|M.leprae_Br4923 -DHVVIKFSIGT-----------NRIGTASRLGIRTDTVLGKKVLEVETR
Mflv_3843|M.gilvum_PYR-GCK VPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGGA
MUL_2318|M.ulcerans_Agy99 VQGALNS-PKSVVAGQD---IPEGVQIQQVLSAIGSDLAGVGAQCRKL-A
MMAR_3072|M.marinum_M VQGALNS-PKSVVAGQD---IPEGAQIQQVLSAIGSDLAGVGAQCQKL-A
MAV_2415|M.avium_104 VQGTLNA-SKALFDSQQ---IPEGEKIDHALAEIGAAAAAIGQQCDAL-A
Mb3933c|M.bovis_AF2122/97 TEIQSTAGPMGVIRAQQ---LPEAGLIESAFADAYASTTAVVGQCHQL-A
Rv3903c|M.tuberculosis_H37Rv TEIQSTAGPMGVIRAQQ---LPEAGLIESAFADAYASTTAVVGQCHQL-A
MSMEG_1870|M.smegmatis_MC2_155 VSNQVSG-SSTAVSTQK---IPEASQIAQAHADLADGVADLANQATNL-A
TH_3868|M.thermoresistible__bu FEPQLAP-VLAVVSAQN---TPETPAIVSGLDELARGISALTDASVEV-A
MAB_3131c|M.abscessus_ATCC_199 ERPAPRPQAP---RPG----APRPGG-----ASPSNMPPRPSPGSMGP-R
Mvan_2314|M.vanbaalenii_PYR-1 ERPAPRPQGPGGPRPGPGAGGPRPGGGPRPGASPGSMPPRPQ-GARPG-G
MLBr_02591|M.leprae_Br4923 GTQLLRPGDSLPLGQSTTPYQSYDAFFDATKVASGWNIDTIKQSLKVV-S
Mflv_3843|M.gilvum_PYR-GCK VLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPGA
.
MUL_2318|M.ulcerans_Agy99 GALDDFADEVADTQDAIRDLLDRFGSVSGLWNQVVAIFEGDAL-------
MMAR_3072|M.marinum_M GALDDFADEVADTQDAIRDLLDRFGSVSGLWNQVMAIFEGDAL-------
MAV_2415|M.avium_104 RTVDEFADRVGHAQQAIRDLLHRIEALGDIGHDIMLIIDGDAW-------
Mb3933c|M.bovis_AF2122/97 AQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDE-------
Rv3903c|M.tuberculosis_H37Rv AQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDE-------
MSMEG_1870|M.smegmatis_MC2_155 ETLNTFADNVQETQDAIRRLLDRVASIDGIINTVKGIFTGDAL-------
TH_3868|M.thermoresistible__bu REVEDFAATVQGTQDAIRRLVGRVS-ISGLFHTVKGILTGDGK-------
MAB_3131c|M.abscessus_ATCC_199 PPRPGGGPRPGGGPR--PGGAGRPGGGGGG--NYRGGGTGTGAPAGGPPG
Mvan_2314|M.vanbaalenii_PYR-1 GPRPGGGPRPGGGPRPTPGGAGRPGGGGGGGGNYRGGGAGGGAPAAG---
MLBr_02591|M.leprae_Br4923 ETIDQTYPHLSAALDGVAKFSDTIGARDKEIKHLIAQAN-----------
Mflv_3843|M.gilvum_PYR-GCK PVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEGTGG
MUL_2318|M.ulcerans_Agy99 ----DEIKEIAEDIRAVLSNLGRQARAQQQLMQQGMQAIDGLVVGMQRYV
MMAR_3072|M.marinum_M ----DEIKEIAEDIQAVLSNLGRQARAQQQLMQQGMQAIDGLVVGMQRYV
MAV_2415|M.avium_104 ----DEIQKIARDVNAVLQHLGQEARAFEQEIRLLMQAADREIVTCQKYA
Mb3933c|M.bovis_AF2122/97 ----DEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHA
Rv3903c|M.tuberculosis_H37Rv ----DEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHA
MSMEG_1870|M.smegmatis_MC2_155 ----DIIKEVVEDIRTLLGNFQRQVKAVGALLEELKNALNDTVTKFQKWA
TH_3868|M.thermoresistible__bu ----DILREVARDVRTVLDNFQRQVKGVIGLLEELATLIGDAATAFQKWL
MAB_3131c|M.abscessus_ATCC_199 AGGGFRGRPGGGGGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRAEYE
Mvan_2314|M.vanbaalenii_PYR-1 -GGGFRGRPGGGGGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRAEYE
MLBr_02591|M.leprae_Br4923 -----QVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAFA
Mflv_3843|M.gilvum_PYR-GCK AVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAGGLG
. .
MUL_2318|M.ulcerans_Agy99 RGQLTQLLGQDVGNPVATVFDTY----------TNTQEGVFKAAVGMVEG
MMAR_3072|M.marinum_M RGQLTQFLGQDVGNPLATVFDTY----------TNTQEGVFKAAVGMVEG
MAV_2415|M.avium_104 RRGLITFLGEDVGNPVATALDFG----------INVQEGVVKGAVGMGLG
Mb3933c|M.bovis_AF2122/97 GKQWDRFLHS---NPVGVVIDGT----------GQQLKGFGEEAFGMAKD
Rv3903c|M.tuberculosis_H37Rv GKQWDRFLHS---NPVGVVIDGT----------GQQLKGFGEEAFGMAKD
MSMEG_1870|M.smegmatis_MC2_155 DKNLREILGDQVGGAISDIIKFQ----------TDLSTGVLNGVINTVAG
TH_3868|M.thermoresistible__bu RPNLVAVFGEQVGGAMADRIELR----------TDLGVGVVTGLIGTVTG
MAB_3131c|M.abscessus_ATCC_199 NMQAPVVGGVRLPHGNGEVIRLARGAS-----LSDFAEKIDANPASLVQA
Mvan_2314|M.vanbaalenii_PYR-1 NMQAPVVGGVRLPHGNGETIRLARGAS-----LSDFAEKINANPASLVQA
MLBr_02591|M.leprae_Br4923 AQVQRLINDNPNLNHVLEQLHQL----------SGILVQHKDDLANTLIQ
Mflv_3843|M.gilvum_PYR-GCK GAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPG
.
MUL_2318|M.ulcerans_Agy99 IEQLNPQRFLIDPQGAAETWKAMTK----TGLINH-------LLNPEEAV
MMAR_3072|M.marinum_M IEQLNPQRFLIDPQGAAETWKAMTK----TGLINH-------LLNPEEAV
MAV_2415|M.avium_104 LVDLSPHWIALDPEGAGATWGGLVKNAWKESFVNA-------AVNPQEFA
Mb3933c|M.bovis_AF2122/97 SWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGG-------ENAPG-VV
Rv3903c|M.tuberculosis_H37Rv SWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGG-------ENAPG-VV
MSMEG_1870|M.smegmatis_MC2_155 TVAFAD----------FDTWKGLGE-----TALAV-------IKDPSLID
TH_3868|M.thermoresistible__bu VVALAD----------ADTWRGLAN-----LALTV-------GPDPTKMP
MAB_3131c|M.abscessus_ATCC_199 LFNLGEMVTATQSVG-DETLELLGGEMNYVVQVVSPE-----DEDRELLE
Mvan_2314|M.vanbaalenii_PYR-1 LFNLGEMVTATQSVG-DETLELLGGEMNYVVQVVSPE-----DEDRELLE
MLBr_02591|M.leprae_Br4923 VAAFLP-----------SLNEAIGSGPFFKVVLHN--------LAPYQIL
Mflv_3843|M.gilvum_PYR-GCK VPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVVDEAGVVTP
.
MUL_2318|M.ulcerans_Agy99 AADKEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAGAGAKGA
MMAR_3072|M.marinum_M AADKEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAGAGAKGA
MAV_2415|M.avium_104 QARLQELKGLVHADDWTRDRPGLGAGEVAFDAATLIAPGLGEAGAAADGA
Mb3933c|M.bovis_AF2122/97 ESWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLGSKGR
Rv3903c|M.tuberculosis_H37Rv ESWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLGSKGR
MSMEG_1870|M.smegmatis_MC2_155 DIGIAAGKEFFAWDQLTGENPGRGIGEAGFNIAGLFVGGPLSKGGTVAKG
TH_3868|M.thermoresistible__bu EILAEMGKTIVAWDKWSGENPGRAAGEAIFNVGSFFT--PVG----VLGG
MAB_3131c|M.abscessus_ATCC_199 SFDLTYGEDEGGEEDLRTRPPVVTVMGHVDHGKTRLLDTIRKANVREGEA
Mvan_2314|M.vanbaalenii_PYR-1 SFDLTYGEDEGGEEDLEIRPPVVTVMGHVDHGKTRLLDTIRNATVREGEA
MLBr_02591|M.leprae_Br4923 QPWVDAAFKKRGID---PENFWRSAGLPEFRFP-----------------
Mflv_3843|M.gilvum_PYR-GCK PAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAATPPSSG
MUL_2318|M.ulcerans_Agy99 AGAARAAEVGGEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKTGRGL
MMAR_3072|M.marinum_M AGAARAAEVGGEAADAAAAVGRGGRLAGEVGDLAGAGRTLGDIGKTGRGL
MAV_2415|M.avium_104 SAAARGAEA---EADAAGAAGR-------VGGIAGARGALTDIAKSTADL
Mb3933c|M.bovis_AF2122/97 D------------------------------ILAGVRGLKERLEPTTPHL
Rv3903c|M.tuberculosis_H37Rv D------------------------------ILAGVRGLKERLEPTTPHL
MSMEG_1870|M.smegmatis_MC2_155 VNKVRRAFD---HADSPPLDLPGRHGLDGNDLSVTGSRVPEVPEIRQDGI
TH_3868|M.thermoresistible__bu TTRATTSLG---RAAS----AFGRG---------VDARTPGIPGT---GI
MAB_3131c|M.abscessus_ATCC_199 GGITQHIGAYQVAVEHDGTERPITFIDTPGHEAFTAMRARGAKATDIAIL
Mvan_2314|M.vanbaalenii_PYR-1 GGITQHIGAYQVTVDLDGTERPITFIDTPGHEAFTAMRARGAKATDIAIL
MLBr_02591|M.leprae_Br4923 -------------------------------DPNGTRFPNGAPPPAPPVL
Mflv_3843|M.gilvum_PYR-GCK SVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPTPEI
:
MUL_2318|M.ulcerans_Agy99 TEDLAN--LGGDLPKADPPVGGRPVALPPP-KPAGAPIEPTPRPVESVP-
MMAR_3072|M.marinum_M TEDLAN--LGGDLPKADPPVGGRPVALPPP-KPAGAPAEPTPRPVESVP-
MAV_2415|M.avium_104 PKNLEG--VTKDLPEIKPPTGGAPVGLGPGGKPIEAPVESAPRPPDGTPG
Mb3933c|M.bovis_AF2122/97 EPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGPLPHSPTESK-
Rv3903c|M.tuberculosis_H37Rv EPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGPLPHSPTESK-
MSMEG_1870|M.smegmatis_MC2_155 PDSVINPAPSNRLDAPSNPGGPEAPVRPPEPPGPTTHNPGGTRPPGGGD-
TH_3868|M.thermoresistible__bu PGRGVEPAPS--------PAG-----RPPAQRADAGH--GGERAP-----
MAB_3131c|M.abscessus_ATCC_199 VVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRAQLTEY
Mvan_2314|M.vanbaalenii_PYR-1 VVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEY
MLBr_02591|M.leprae_Br4923 EGTPENPGPAVPPGSPCSYTPAHPGGNNTIGDEMGLPRPWNPLPCAGAT-
Mflv_3843|M.gilvum_PYR-GCK TLNPANSGIDIATPPAPGLPGAPLEATANITTPGTPGVPGAPVNSSIDVA
MUL_2318|M.ulcerans_Agy99 --------------PG--------------KPALEAP-------------
MMAR_3072|M.marinum_M --------------PG--------------KPALEAP-------------
MAV_2415|M.avium_104 AQRGSPPVATSPASPGPAGDSGAGPHGPSSSPAPAAPPGGPVGPHDPAPA
Mb3933c|M.bovis_AF2122/97 ------------------------------PPPVDRP-------------
Rv3903c|M.tuberculosis_H37Rv ------------------------------PPPVDRP-------------
MSMEG_1870|M.smegmatis_MC2_155 ------------------------------GPPPESP-------------
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 N-------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 G-------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK TPG-------------EVGVPAAPIERSMTVTTPDTPG------------
MUL_2318|M.ulcerans_Agy99 -----------------------------SGAPG---SVVPGR-------
MMAR_3072|M.marinum_M -----------------------------SGAPG---SVVPGR-------
MAV_2415|M.avium_104 PAPAASPGGPGGSGGVHDPAPAPAPAPAASGGPGDPASVPSGGPHEPASV
Mb3933c|M.bovis_AF2122/97 ---------------------------AEPVAP-----------------
Rv3903c|M.tuberculosis_H37Rv ---------------------------AEPVAP-----------------
MSMEG_1870|M.smegmatis_MC2_155 ------------------------HRPVGPADPGPT--------------
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK ----------------------------APGAPANAAVDVATP-------
MUL_2318|M.ulcerans_Agy99 --------------------SEPAFGPHDPASAPVAGSHPAATAVTPGER
MMAR_3072|M.marinum_M --------------------SEPAFGPHDPASAPVAGSHPAATAVTPGER
MAV_2415|M.avium_104 PAEEPREPVSVPAGGVHDPVAEPTGGPHEPASVPAAGSRLASVQAAAGDG
Mb3933c|M.bovis_AF2122/97 --------------------SSASAGQPRVSAATTPGTHVPHGLPQPGEH
Rv3903c|M.tuberculosis_H37Rv --------------------SSASAGQPRVSAATTPGTHVPHGLPQPGEH
MSMEG_1870|M.smegmatis_MC2_155 -----------------RGDAPPPHTPSTPEPSHPGSSSVGEPGIRGNPE
TH_3868|M.thermoresistible__bu --------------------VEPPAHETVLDHIENTAGNLNNLGVR-NRE
MAB_3131c|M.abscessus_ATCC_199 ------------------LVAEDFGGDTMFVDISARQGTNIEQLLEAVLL
Mvan_2314|M.vanbaalenii_PYR-1 ------------------LVPEEYGGDAMFVDISAKQGTNIEALLEAVIL
MLBr_02591|M.leprae_Br4923 --------------------AGPYGGPAFPAPIDVQTSPPNPDGLPLLPG
Mflv_3843|M.gilvum_PYR-GCK ------------------PAPGVPGAPVVGEAGVTTPGAPGAPGAPANAA
MUL_2318|M.ulcerans_Agy99 LSPVTPHVG--EPARAPGVPVGAAAG-PVPAGAHSAPA--AIPAAPGAHV
MMAR_3072|M.marinum_M VSPVTPHVG--EPARAPGVPVGAAAG-PVPAGAHSAPA--AIPAAPGAHV
MAV_2415|M.avium_104 LPSATPQLFDHTPSQVP-VPAGGSSGEAASVGAHSPSS--ASSAAP--HF
Mb3933c|M.bovis_AF2122/97 VPAQAPPAT----TLLGGPPVESAPATAHQPQWATTPA--APAAAP---H
Rv3903c|M.tuberculosis_H37Rv VPAQAPPAT----TLLGGPPVESAPATAHQPQWATTPA--APAAAP---H
MSMEG_1870|M.smegmatis_MC2_155 PSHTPPSVDHTPQHAPEPATPAAQNDAPHTSAESNSTP--THQPSTSDAP
TH_3868|M.thermoresistible__bu DTEEQPSN------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 TADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSIVA
Mvan_2314|M.vanbaalenii_PYR-1 TADASLDLRANPDMEAQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSVVA
MLBr_02591|M.leprae_Br4923 IAIAGRPGD--PAPNVPGTPVPLPPNAPPGARTEQLAP-----AAPAQDS
Mflv_3843|M.gilvum_PYR-GCK VDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAPGVP
MUL_2318|M.ulcerans_Agy99 MTGAGRPAELSAPHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHG
MMAR_3072|M.marinum_M MTGAGRPAELSAPHGGVPQGLGDAGPSGGHPHGLPPHGGGPHGPGDASHG
MAV_2415|M.avium_104 ESPGGRPSEVPAPNGGA-HGPGESGPAGGHPPGEPPHGGKPSGDG----G
Mb3933c|M.bovis_AF2122/97 STPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHR
Rv3903c|M.tuberculosis_H37Rv STPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHR
MSMEG_1870|M.smegmatis_MC2_155 ASTHSPTQHIGGSVGGEHSAISSDSNIGSAEHHRPVTDESRNWADEQAHR
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 GDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNLLVVDEDRI
Mvan_2314|M.vanbaalenii_PYR-1 GDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRI
MLBr_02591|M.leprae_Br4923 SAPHEPREQLSAPLINPGGTGGSGGAGGSRN-------------------
Mflv_3843|M.gilvum_PYR-GCK GAPVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGLAT
MUL_2318|M.ulcerans_Agy99 ARHAEPPRDGTAHG---------TADGGDAHGDDVSGHGLSAEKRDEIIA
MMAR_3072|M.marinum_M ARHAEPPRDGTAHG---------TADGGDAHGDDVSGHGLSAEKRDEIIA
MAV_2415|M.avium_104 PPDEDSHRDGTPGN---------GDDGAAGEIDDGP-AGVDGQSTPAKVA
Mb3933c|M.bovis_AF2122/97 EQQLAMHSNEPAGE---------GWHRLSDEAVDPQYGEPLSRHWDFTDN
Rv3903c|M.tuberculosis_H37Rv EQQLAMHSNEPAGE---------GWHRLSDEAVDPQYGEPLSRHWDFTDN
MSMEG_1870|M.smegmatis_MC2_155 PAEQQPAHNAAAEQPVTHDRNSAETNESREPAYSSAVNGPQPAMGPMMSP
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 ARQIADRRSARKRN---------ALAARSRKRISLDDLDAALKETSQLNL
Mvan_2314|M.vanbaalenii_PYR-1 ARQIADRRSARKRN---------ALAARTRKRISLEDLDSALKETSQLNL
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PPGPGAPGAPVVGDAG-VATPPGPGVPGAPIVDEAGLATPPAPVAPVEGA
MUL_2318|M.ulcerans_Agy99 MRKGSRPDPSEYLSPEYIQGHLDRFTGGATRFMPESNLDKYG-IAQRD--
MMAR_3072|M.marinum_M MPKGSRPDPSEYLSPEYIQGHLDRFTDGATRFMPESNLDKYG-IAQRD--
MAV_2415|M.avium_104 GVDYPLPPSDALRVLEHPGAELQRLADGG---VPSSILEGYEPLAGRSVD
Mb3933c|M.bovis_AF2122/97 PADRSRINPVVAQLMEDPNAPFGRDPQGQP-YTQERYQERFNSVGPWG--
Rv3903c|M.tuberculosis_H37Rv PADRSRINPVVAQLMEDPNAPFGRDPQGQP-YTQERYQERFNSVGPWG--
MSMEG_1870|M.smegmatis_MC2_155 GVGSGPGSPMTPHAPGPVHGGGESPSPAAKLPTPDTSTRGPETRPSHTGS
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 ILKGDNAGTVEALEEALLGIAIDDEVQLRVIDRGVGGVTETNVNLASASD
Mvan_2314|M.vanbaalenii_PYR-1 ILKGDNSGTVEALEEALLGIQVDDEVELRVIDRGVGGVTETNVNLASASD
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK GGAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGG
MUL_2318|M.ulcerans_Agy99 --GTSFVMPKS--------EADAMIAGTGG--------DLRLMEEELGLP
MMAR_3072|M.marinum_M --GTSFVMPKS--------EADAMIAGTGG--------DLRLMEEELGLP
MAV_2415|M.avium_104 DFNREFTIETSNGERGWDWEAQAPENGFAGNPIESNHIPAGLHFDRIGPN
Mb3933c|M.bovis_AF2122/97 --QQYSNFPPN--------NGAVPGTRIAYTNLEKFLSDYGPQLDRIGGD
Rv3903c|M.tuberculosis_H37Rv --QQYSNFPPN--------NGAVPGTRIAYTNLEKFLSDYGPQLDRIGGD
MSMEG_1870|M.smegmatis_MC2_155 PETPRAQQPSAVGPTPGSTPSAPVHSSADQSRQSASTSPASSTSEQTAPK
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 AIIIGFNVRAEG--------KATELANREGVDIRYYSVIYQAIDEIESAL
Mvan_2314|M.vanbaalenii_PYR-1 AIIIGFNVRAEG--------KATELANREGVEIRYYSIIYQAIDEIESAL
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK GAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGG
MUL_2318|M.ulcerans_Agy99 EG-FLDSNQIVRIDIEDPR----QFNLRIPSGNE----------------
MMAR_3072|M.marinum_M EG-FLDSNQIVRIDIEDPR----QFNLRIPSGNE----------------
MAV_2415|M.avium_104 GGGFLSPEGVPLAERATPPGLAAQYHVFEGTGRE----------------
Mb3933c|M.bovis_AF2122/97 QGKYLAIMEHGRPASWEQR----ALHVTSLRDPY----------------
Rv3903c|M.tuberculosis_H37Rv QGKYLAIMEHGRPASWEQR----ALHVTSLRDPY----------------
MSMEG_1870|M.smegmatis_MC2_155 EHGTAPGSSVPPSDSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSD
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 KGMLKPVYEEVELGRAEIRAMFRSSKVGNIAGCLVTSG------------
Mvan_2314|M.vanbaalenii_PYR-1 KGMLKPVYEEKELGRAEIRAIFRSSKVGNIAGCLVQSG------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPG
MUL_2318|M.ulcerans_Agy99 ------AGANEQWIPG-------------GLLPTGASEAVVDGGK---VP
MMAR_3072|M.marinum_M ------AGANEQWIPG-------------GRLPTGASEAVVDGGK---IP
MAV_2415|M.avium_104 ------IPAGKDWVVQHGPAKE-----AFGQPGGGDQWIVLDRATNRPVP
Mb3933c|M.bovis_AF2122/97 ------HAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQN-EMRK
Rv3903c|M.tuberculosis_H37Rv ------HAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQN-EMRK
MSMEG_1870|M.smegmatis_MC2_155 LDYNPMLDENGHYVPGSLPSYDELLRLTRTEPDSAHYWSGRDANGVGVGP
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 ----IIRRNAKARLLRDNIVVAETVTISSLRREKDDVVEVRDGYECGLTL
Mvan_2314|M.vanbaalenii_PYR-1 ----IMRRNAKARLLRDNVVVAENLTISSLKREKDDVTEVRDGYECGLTL
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK APVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTP
MUL_2318|M.ulcerans_Agy99 QGDYTVTDVFEEK-------------------------------------
MMAR_3072|M.marinum_M QGDYTVTDVFEEK-------------------------------------
MAV_2415|M.avium_104 VDELIRRRLLREITPPNDKLAIGYRGS-----------------------
Mb3933c|M.bovis_AF2122/97 VEELIRRGVLRQ--------------------------------------
Rv3903c|M.tuberculosis_H37Rv VEELIRRGVLRQ--------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 DGSGIAERIAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAA
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 TYNDIKEGDVIEAYELREKERV----------------------------
Mvan_2314|M.vanbaalenii_PYR-1 TYSDIKEGDVIETYELVEKART----------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PAPGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTV
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 YAENARGDVTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRA
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGT
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 TELFHRTTSADGPAPNGQMEPTARHDGLTSETDSRTLRDTDQDSIDRASN
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVP
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 KPDADVRAEPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGPDGRYKISGH
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK GTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGT
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 GDYHSGDGTFTVPADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTY
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK DWSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 YPGETMPNYTLLPPDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLG
TH_3868|M.thermoresistible__bu --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 -------------------------------------
MMAR_3072|M.marinum_M -------------------------------------
MAV_2415|M.avium_104 -------------------------------------
Mb3933c|M.bovis_AF2122/97 -------------------------------------
Rv3903c|M.tuberculosis_H37Rv -------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 SWNHRVFDVHGIYHQDTYDFIEKYPWPEPENLGDDDW
TH_3868|M.thermoresistible__bu -------------------------------------
MAB_3131c|M.abscessus_ATCC_199 -------------------------------------
Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------
MLBr_02591|M.leprae_Br4923 -------------------------------------
Mflv_3843|M.gilvum_PYR-GCK -------------------------------------