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PSNSGGGGGVSGIRIEVDPQVLIRAGESMLSLGNQLDMLMGALGPMLSSGIASGIDLAGLAMALDYGDLT QKFSNTLANGANTFKTVGLRLQASGHNYANADAVSTIGGGAPTGGVKGKFDETKPVDARDSPSLSVVPPP PAWYLVGSFLGPTAWPSGNPAMLRLTAAQWENLATGFSAVSNQVSGSSTAVSTQKIPEASQIAQAHADLA DGVADLANQATNLAETLNTFADNVQETQDAIRRLLDRVASIDGIINTVKGIFTGDALDIIKEVVEDIRTL LGNFQRQVKAVGALLEELKNALNDTVTKFQKWADKNLREILGDQVGGAISDIIKFQTDLSTGVLNGVINT VAGTVAFADFDTWKGLGETALAVIKDPSLIDDIGIAAGKEFFAWDQLTGENPGRGIGEAGFNIAGLFVGG PLSKGGTVAKGVNKVRRAFDHADSPPLDLPGRHGLDGNDLSVTGSRVPEVPEIRQDGIPDSVINPAPSNR LDAPSNPGGPEAPVRPPEPPGPTTHNPGGTRPPGGGDGPPPESPHRPVGPADPGPTRGDAPPPHTPSTPE PSHPGSSSVGEPGIRGNPEPSHTPPSVDHTPQHAPEPATPAAQNDAPHTSAESNSTPTHQPSTSDAPAST HSPTQHIGGSVGGEHSAISSDSNIGSAEHHRPVTDESRNWADEQAHRPAEQQPAHNAAAEQPVTHDRNSA ETNESREPAYSSAVNGPQPAMGPMMSPGVGSGPGSPMTPHAPGPVHGGGESPSPAAKLPTPDTSTRGPET RPSHTGSPETPRAQQPSAVGPTPGSTPSAPVHSSADQSRQSASTSPASSTSEQTAPKEHGTAPGSSVPPS DSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSDLDYNPMLDENGHYVPGSLPSYDELLRLTRTEPD SAHYWSGRDANGVGVGPDGSGIAERIAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAAYAE NARGDVTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRATELFHRTTSADGPAPNGQMEPTA RHDGLTSETDSRTLRDTDQDSIDRASNKPDADVRAEPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGPDG RYKISGHGDYHSGDGTFTVPADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTYYPGETMPNYTLLP PDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLGSWNHRVFDVHGIYHQDTYDFIEKYPWPEPENLG DDDW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1870 | - | - | 100% (1265) | hypothetical protein MSMEG_1870 |
| M. smegmatis MC2 155 | MSMEG_1188 | - | 2e-12 | 25.16% (306) | hypothetical protein MSMEG_1188 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 1e-10 | 25.25% (396) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3933c | - | 9e-37 | 25.67% (713) | hypothetical protein Mb3933c |
| M. gilvum PYR-GCK | Mflv_3843 | - | 5e-16 | 25.00% (476) | hypothetical protein Mflv_3843 |
| M. tuberculosis H37Rv | Rv3903c | - | 9e-37 | 25.67% (713) | hypothetical protein Rv3903c |
| M. leprae Br4923 | MLBr_02591 | mce1C | 2e-09 | 30.34% (178) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4317 | - | 3e-39 | 43.96% (207) | hypothetical protein MAB_4317 |
| M. marinum M | MMAR_3072 | - | 3e-61 | 28.77% (702) | hypothetical protein MMAR_3072 |
| M. avium 104 | MAV_2415 | - | 2e-60 | 26.26% (872) | hypothetical protein MAV_2415 |
| M. thermoresistible (build 8) | TH_3868 | - | 1e-68 | 44.19% (353) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2318 | - | 7e-61 | 28.88% (703) | hypothetical protein MUL_2318 |
| M. vanbaalenii PYR-1 | Mvan_2552 | - | 7e-16 | 24.44% (487) | hypothetical protein Mvan_2552 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1870|M.smegmatis_MC2_155 MPSNSGGGGGVSGIRIEVDPQVLIRAGESMLSLGNQLDMLMGALGPMLSS
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG
Rv3903c|M.tuberculosis_H37Rv ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG
MMAR_3072|M.marinum_M ------------MAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGFS-
MUL_2318|M.ulcerans_Agy99 ------MGKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGFS-
MAV_2415|M.avium_104 ------------MAPLAVDPEAMYAAGSAVAAIGDSLAANLTILTAGVS-
Mflv_3843|M.gilvum_PYR-GCK ----------MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPC
Mvan_2552|M.vanbaalenii_PYR-1 ----------MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPC
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 G-IASGIDLAGLAMALDYGDLTQKFSNTLANGANTFKTVGLRLQASGHNY
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNY
Rv3903c|M.tuberculosis_H37Rv CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNY
MMAR_3072|M.marinum_M --ANTGQDAAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNY
MUL_2318|M.ulcerans_Agy99 --ANTGQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNY
MAV_2415|M.avium_104 --AHTGVDRAGEVFGLGYQDSAESMLKAAAGVVNACRKCGALIQQGASNY
Mflv_3843|M.gilvum_PYR-GCK VGILQQIVTRPGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPP
Mvan_2552|M.vanbaalenii_PYR-1 VGILQQVISRPGDIPQALTETARSFTNPGQPAPPVVRPPASSSSSVGTPP
MAB_4317|M.abscessus_ATCC_1997 -------------MSLPLADIKRAKVQSFRDVADALDGMAGANRDMKRGV
MLBr_02591|M.leprae_Br4923 ------------MRTLELPNRLRSGLIGVLVVLLIIG-VGQSFTSVPILF
MSMEG_1870|M.smegmatis_MC2_155 ANADAVSTIGGGAPTGGVKGKFDETKPVDARDSPSLSVVPPPPAWYLVGS
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 SLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAPKGWGWVAP
Rv3903c|M.tuberculosis_H37Rv SLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAPKGWGWVAP
MMAR_3072|M.marinum_M SAAEAASTLGGGAGVLPAP-SEPAQFTAPGAPGTLGSGVLAPALWSVVEA
MUL_2318|M.ulcerans_Agy99 SAAEAASTLGGGAGVLPAP-SEPAQFTAPGAPGTLGSGVLAPALWSVVEA
MAV_2415|M.avium_104 SAAEAASTLGGGSGALPAP-SAPADLAAPGPPGTWGKGEPPPLLWAVIQA
Mflv_3843|M.gilvum_PYR-GCK VPGRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTP
Mvan_2552|M.vanbaalenii_PYR-1 VPPTPPGSVVRPSSGATPPVPPTPGTPASTTTGVGTPPVPPTPPGSTVRP
MAB_4317|M.abscessus_ATCC_1997 ERLPIMGDGWKGVSGEAAHHDLDAHGKYLDG-HAQAQQSAAAKIRAAADE
MLBr_02591|M.leprae_Br4923 ARPSYYGQFTDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIGTN
MSMEG_1870|M.smegmatis_MC2_155 FLGPTAWPSGNPAMLRLTAAQWENLATGFSAVSNQVSG-SSTAVS--TQK
TH_3868|M.thermoresistible__bu -------------MLRLTVAQWRNFAHGFAVFEPQLAP-VLAVVS--AQN
Mb3933c|M.bovis_AF2122/97 YIG-MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIR--AQQ
Rv3903c|M.tuberculosis_H37Rv YIG-MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIR--AQQ
MMAR_3072|M.marinum_M FVG-DLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS-PKSVVA--GQD
MUL_2318|M.ulcerans_Agy99 FVG-DLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS-PKSVVA--GQD
MAV_2415|M.avium_104 LVS-EVWPDGDEAGLHAAASRWHGFAAAMNGVQGTLNA-SKALFD--SQQ
Mflv_3843|M.gilvum_PYR-GCK ASG--ATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPP
Mvan_2552|M.vanbaalenii_PYR-1 AAG--ATPPAPPVPGVPAGTPIGGGTPPLPPVPGAPAGTPVANVAPPSPP
MAB_4317|M.abscessus_ATCC_1997 FEG-------VQQLLKKIENDAAQGKFTINYDTGEVTP-PSGKYD--KNE
MLBr_02591|M.leprae_Br4923 RIG-------TASRLGIRTDTVLGKKVLEVETRGTQLLRPGDSLP-LGQS
MSMEG_1870|M.smegmatis_MC2_155 IPEASQIAQAHADLADGVADLANQATNLAETLNTFADNVQETQDAIRRLL
TH_3868|M.thermoresistible__bu TPETPAIVSGLDELARGISALTDASVEVAREVEDFAATVQGTQDAIRRLV
Mb3933c|M.bovis_AF2122/97 LPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLL
Rv3903c|M.tuberculosis_H37Rv LPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLL
MMAR_3072|M.marinum_M IPEGAQIQQVLSAIGSDLAGVGAQCQKLAGALDDFADEVADTQDAIRDLL
MUL_2318|M.ulcerans_Agy99 IPEGVQIQQVLSAIGSDLAGVGAQCRKLAGALDDFADEVADTQDAIRDLL
MAV_2415|M.avium_104 IPEGEKIDHALAEIGAAAAAIGQQCDALARTVDEFADRVGHAQQAIRDLL
Mflv_3843|M.gilvum_PYR-GCK VPGAPVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGV
Mvan_2552|M.vanbaalenii_PYR-1 VPGVPVIGDGGAALPPLPPVPGGPAAVPAGVVTPPAPPIPGGPAAMPAGV
MAB_4317|M.abscessus_ATCC_1997 LDYLTNTLRQISAAGGVANADLEAAVKAAQTLPDPSGAVAQGLPAMPGSA
MLBr_02591|M.leprae_Br4923 TTPYQSYDAFFDATKVASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGV
: *
MSMEG_1870|M.smegmatis_MC2_155 DRVASIDGIINTVKGIFTGDA---------LDIIKEVVEDIRTLLGNFQR
TH_3868|M.thermoresistible__bu GRVS-ISGLFHTVKGILTGDG---------KDILREVARDVRTVLDNFQR
Mb3933c|M.bovis_AF2122/97 ARICDPLTGIKEVWEFLTDQD---------EDEIQRIAHDIAVVVDQFSG
Rv3903c|M.tuberculosis_H37Rv ARICDPLTGIKEVWEFLTDQD---------EDEIQRIAHDIAVVVDQFSG
MMAR_3072|M.marinum_M DRFGSVSGLWNQVMAIFEGDA---------LDEIKEIAEDIQAVLSNLGR
MUL_2318|M.ulcerans_Agy99 DRFGSVSGLWNQVVAIFEGDA---------LDEIKEIAEDIRAVLSNLGR
MAV_2415|M.avium_104 HRIEALGDIGHDIMLIIDGDA---------WDEIQKIARDVNAVLQHLGQ
Mflv_3843|M.gilvum_PYR-GCK ALPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGP
Mvan_2552|M.vanbaalenii_PYR-1 AAPPAP-APPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGGGAGAP
MAB_4317|M.abscessus_ATCC_1997 IKPGGVAAGLEHLAAPDPNGDP-------GATKAAAAGADTQANYKEWYP
MLBr_02591|M.leprae_Br4923 AKFSDTIGARDKEIKHLIAQAN----------QVASVLGDRGAQVDRLLV
MSMEG_1870|M.smegmatis_MC2_155 QVKAVGALLEELKNALNDTVTKFQKWADKNLREILGDQVGGAISDIIKFQ
TH_3868|M.thermoresistible__bu QVKGVIGLLEELATLIGDAATAFQKWLRPNLVAVFGEQVGGAMADRIELR
Mb3933c|M.bovis_AF2122/97 EVDALAAEITAVVSHAEAVITAMADHAGKQWDRFLHS---NPVGVVIDGT
Rv3903c|M.tuberculosis_H37Rv EVDALAAEITAVVSHAEAVITAMADHAGKQWDRFLHS---NPVGVVIDGT
MMAR_3072|M.marinum_M QARAQQQLMQQGMQAIDGLVVGMQRYVRGQLTQFLGQDVGNPLATVFDTY
MUL_2318|M.ulcerans_Agy99 QARAQQQLMQQGMQAIDGLVVGMQRYVRGQLTQLLGQDVGNPVATVFDTY
MAV_2415|M.avium_104 EARAFEQEIRLLMQAADREIVTCQKYARRGLITFLGEDVGNPVATALDFG
Mflv_3843|M.gilvum_PYR-GCK GGGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPA
Mvan_2552|M.vanbaalenii_PYR-1 GAPVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLVAPPG
MAB_4317|M.abscessus_ATCC_1997 RTPGSGDKLTIDPSKAGSFTGTVGALEKLPGAPKPADGFGSGVARQFGQG
MLBr_02591|M.leprae_Br4923 NTKTLIAAFNERGRAVDALLGNVAAFAAQVQRLINDNPNLNHVLEQLHQL
.
MSMEG_1870|M.smegmatis_MC2_155 TDLSTGVLNGVINTVAGTVAFAD----------FDTWKGLGE-----TAL
TH_3868|M.thermoresistible__bu TDLGVGVVTGLIGTVTGVVALAD----------ADTWRGLAN-----LAL
Mb3933c|M.bovis_AF2122/97 GQQLKGFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGL
Rv3903c|M.tuberculosis_H37Rv GQQLKGFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGL
MMAR_3072|M.marinum_M TNTQEGVFKAAVGMVEGIEQLNPQRFLIDPQGAAETWKAMTK----TGLI
MUL_2318|M.ulcerans_Agy99 TNTQEGVFKAAVGMVEGIEQLNPQRFLIDPQGAAETWKAMTK----TGLI
MAV_2415|M.avium_104 INVQEGVVKGAVGMGLGLVDLSPHWIALDPEGAGATWGGLVKNAWKESFV
Mflv_3843|M.gilvum_PYR-GCK PPAPAPPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEG
Mvan_2552|M.vanbaalenii_PYR-1 PPAPGVPVVDQAGVVAPPGPPAPGVPVVDEAGVVTPPGPGAPGVPVVGEA
MAB_4317|M.abscessus_ATCC_1997 VNSRVDGIIDEAKNLTGQGGPGS-------PGVAESWAKFALG-----TA
MLBr_02591|M.leprae_Br4923 SGILVQHKDDLANTLIQVAAFLP-----------SLNEAIGSGPFFKVVL
MSMEG_1870|M.smegmatis_MC2_155 AVIKDPSLIDDIGIAAGKE---------------FFAWDQLTGENPGRGI
TH_3868|M.thermoresistible__bu TVGPDPTKMPEILAEMGKT---------------IVAWDKWSGENPGRAA
Mb3933c|M.bovis_AF2122/97 GGENAPG-VVESWKQFGKS---------------LIHWDEWTTN-PNEAL
Rv3903c|M.tuberculosis_H37Rv GGENAPG-VVESWKQFGKS---------------LIHWDEWTTN-PNEAL
MMAR_3072|M.marinum_M NHLLNPEEAVAADKEMVKG---------------LLHLEDWRRDRPGLGF
MUL_2318|M.ulcerans_Agy99 NHLLNPEEAVAADKEMVKG---------------LLHLEDWRRDRPGLGF
MAV_2415|M.avium_104 NAAVNPQEFAQARLQELKG---------------LVHADDWTRDRPGLGA
Mflv_3843|M.gilvum_PYR-GCK GVVTPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPG
Mvan_2552|M.vanbaalenii_PYR-1 GVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPG
MAB_4317|M.abscessus_ATCC_1997 DQMANPLGSLPGEVKDAVN-------------------------DPAGFA
MLBr_02591|M.leprae_Br4923 HNLAPYQILQPWVDAAFKK---------------RGIDPENFWRSAGLPE
.
MSMEG_1870|M.smegmatis_MC2_155 GEAGFNIAGLFVGGPLSKGGTVAKGVNKVRRAFDHADSPPL---------
TH_3868|M.thermoresistible__bu GEAIFNVGSFFT--PVG----VLGGTTRATTSLGRAAS------------
Mb3933c|M.bovis_AF2122/97 GKTVFDAATLALPGGPLSKLGSKGRD------------------------
Rv3903c|M.tuberculosis_H37Rv GKTVFDAATLALPGGPLSKLGSKGRD------------------------
MMAR_3072|M.marinum_M GGNLFDVATLFVPGAGGAGAGAKGAAGAARAAEVGGEAADAAAAVGRGGR
MUL_2318|M.ulcerans_Agy99 GGNLFDVATLFVPGAGGAGAGAKGAAGAARAAEVGGEAADAAAAAGRGGR
MAV_2415|M.avium_104 GEVAFDAATLIAPGLGEAGAAADGASAAARGAEA---EADAAGAAGR---
Mflv_3843|M.gilvum_PYR-GCK APVVDEAGVVTPPAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFS-
Mvan_2552|M.vanbaalenii_PYR-1 VPVVDEAGVVTPPAPGAPGVPVDGGAELVTPPGPGAPGTPTVSSVETFS-
MAB_4317|M.abscessus_ATCC_1997 GKKLFDVSSIAATGPLGGEAAAGARG------------------------
MLBr_02591|M.leprae_Br4923 FRFPDPNGTRFPNGAPPPAPPVLEGT------------------------
.
MSMEG_1870|M.smegmatis_MC2_155 ------DLPGRHGLDGNDLSVTGSRVPEVPEIRQDGIPDSVINPAPSNRL
TH_3868|M.thermoresistible__bu -------AFGRG---------VDARTPGIPGT---GIPGRGVEPAPS---
Mb3933c|M.bovis_AF2122/97 ------ILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPA
Rv3903c|M.tuberculosis_H37Rv ------ILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPA
MMAR_3072|M.marinum_M LAGEVGDLAGAGRTLGDIGKTGRGLTEDLAN--LGGDLPKADPPVGGRPV
MUL_2318|M.ulcerans_Agy99 LAGEVGDLAGAGRTLGDIGKTGRGLTEDLAN--LGGDLPKADPPVGGRPV
MAV_2415|M.avium_104 ----VGGIAGARGALTDIAKSTADLPKNLEG--VTKDLPEIKPPTGGAPV
Mflv_3843|M.gilvum_PYR-GCK ----PPAPPAATPPSSGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPG
Mvan_2552|M.vanbaalenii_PYR-1 ----PPAPPAPGTPSSGSIETFSPPAPPTPGTPANSSVEIVTPPPPGVPG
MAB_4317|M.abscessus_ATCC_1997 ------------------------LLGDLTGAETRALTHDIPDTHHG---
MLBr_02591|M.leprae_Br4923 --------------------------PENPGPAVPPGSPCSYTPAHPGGN
.
MSMEG_1870|M.smegmatis_MC2_155 DAPSNPGGPEAPVRPPEPPGPTTHN-------------------------
TH_3868|M.thermoresistible__bu -----PAG-----RPPAQRADAGH--------------------------
Mb3933c|M.bovis_AF2122/97 PAPAAKPAPVPANGPLPHSPTESK--------------------------
Rv3903c|M.tuberculosis_H37Rv PAPAAKPAPVPANGPLPHSPTESK--------------------------
MMAR_3072|M.marinum_M ALPPP-KPAGAPAEPTPRPVESVP---------------PG---------
MUL_2318|M.ulcerans_Agy99 ALPPP-KPAGAPIEPTPRPVESVP---------------PG---------
MAV_2415|M.avium_104 GLGPGGKPIEAPVESAPRPPDGTPGAQRGSPPVATSPASPGPAGDSGAGP
Mflv_3843|M.gilvum_PYR-GCK LPSEGSTTYTTPPTPEITLNPANSG-------------------------
Mvan_2552|M.vanbaalenii_PYR-1 VPGEGSTTYTTPPTPEITLNPANSS-------------------------
MAB_4317|M.abscessus_ATCC_1997 ------------PAPLDHPSPHVDH-------------------------
MLBr_02591|M.leprae_Br4923 NTIGDEMGLPRPWNPLPCAGATAG--------------------------
.
MSMEG_1870|M.smegmatis_MC2_155 -----PGGTRPPGGG-----------------------------DGPPPE
TH_3868|M.thermoresistible__bu ------GGERAP--------------------------------------
Mb3933c|M.bovis_AF2122/97 -----PPPVDRP--------------------------------------
Rv3903c|M.tuberculosis_H37Rv -----PPPVDRP--------------------------------------
MMAR_3072|M.marinum_M -----KPALEAP--------------------------------------
MUL_2318|M.ulcerans_Agy99 -----KPALEAP--------------------------------------
MAV_2415|M.avium_104 HGPSSSPAPAAPPGGPVGPHDPAPAPAPAASPGGPGGSGGVHDPAPAPAP
Mflv_3843|M.gilvum_PYR-GCK IDIATPPAPGLPG------------------------------APLEATA
Mvan_2552|M.vanbaalenii_PYR-1 IDVATPPGPGVPG------------------------------VPVEASA
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 SPHRPVGPADPGPTRGD----------------------------APPPH
TH_3868|M.thermoresistible__bu ---------------------------------------------VEPPA
Mb3933c|M.bovis_AF2122/97 --AEPVAP-------------------------------------SSASA
Rv3903c|M.tuberculosis_H37Rv --AEPVAP-------------------------------------SSASA
MMAR_3072|M.marinum_M ----SGAPG---SVVPGR---------------------------SEPAF
MUL_2318|M.ulcerans_Agy99 ----SGAPG---SVVPGR---------------------------SEPAF
MAV_2415|M.avium_104 APAASGGPGDPASVPSGGPHEPASVPAEEPREPVSVPAGGVHDPVAEPTG
Mflv_3843|M.gilvum_PYR-GCK NITTPGTPG-----------------------------------VPGAPV
Mvan_2552|M.vanbaalenii_PYR-1 NVSTPPVPG-----------------------------------VPGAPV
MAB_4317|M.abscessus_ATCC_1997 ----------------------------------------------PPTD
MLBr_02591|M.leprae_Br4923 -----------------------------------------------PYG
.
MSMEG_1870|M.smegmatis_MC2_155 TPSTPEPSHPGSSSVGEPGIRGNPEPSHTPPSVDHTPQHAPEPATPAAQN
TH_3868|M.thermoresistible__bu HETVLDHIENTAGNLNNLGVR-NREDTEEQPSN-----------------
Mb3933c|M.bovis_AF2122/97 GQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPAT----TLLGGPPVESAP
Rv3903c|M.tuberculosis_H37Rv GQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPAT----TLLGGPPVESAP
MMAR_3072|M.marinum_M GPHDPASAPVAGSHPAATAVTPGERVSPVTPHVG--EPARAPGVPVGAAA
MUL_2318|M.ulcerans_Agy99 GPHDPASAPVAGSHPAATAVTPGERLSPVTPHVG--EPARAPGVPVGAAA
MAV_2415|M.avium_104 GPHEPASVPAAGSRLASVQAAAGDGLPSATPQLFDHTPSQVP-VPAGGSS
Mflv_3843|M.gilvum_PYR-GCK NSSIDVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVATPPAP
Mvan_2552|M.vanbaalenii_PYR-1 NSSVEVATPAEVGVPGTPIERSTTLTTPPTPGVPGTPVNSSVEVATPPAP
MAB_4317|M.abscessus_ATCC_1997 SDHHAPAVSDHNGGSGGDHSTPGDSPPHFAPLPD----TGPYQLPERAQL
MLBr_02591|M.leprae_Br4923 GPAFPAPIDVQTSPPNPDGLPLLPGIAIAGRPGD-----PAPNVPGTPVP
.
MSMEG_1870|M.smegmatis_MC2_155 DAPHTSAESNSTPTHQPSTSDAPASTHSPTQHIGGSVGGEHSAISSDSNI
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 ATAHQPQWATTPAAPAAAP---HSTPGGVHSTESGPHGRSLSAHGSEPTH
Rv3903c|M.tuberculosis_H37Rv ATAHQPQWATTPAAPAAAP---HSTPGGVHSTESGPHGRSLSAHGSEPTH
MMAR_3072|M.marinum_M G-PVPAGAHSAPAAIPAAPGAHVMTGAGRPAELSAPHGGVPQGLGDAGPS
MUL_2318|M.ulcerans_Agy99 G-PVPAGAHSAPAAIPAAPGAHVMTGAGRPAELSAPHGGVPHGLGDAGPS
MAV_2415|M.avium_104 GEAASVGAHSPSSASSAAP--HFESPGGRPSEVPAPNGGA-HGPGESGPA
Mflv_3843|M.gilvum_PYR-GCK GVPGAPVVGEAGVTTPGAPG-APGAPANAAVDVATPPAPGVPGAPVVGEA
Mvan_2552|M.vanbaalenii_PYR-1 GAPGVPVVDEAGVVTPPGPG-APGVPVVGEAGVVTPPGPGAPGVPVVDEA
MAB_4317|M.abscessus_ATCC_1997 ATPSDGAFFWSGRNVDGTGIGPISAGGNGAADLIADGSRATTLEGLLDSQ
MLBr_02591|M.leprae_Br4923 LPPNAPPGARTEQLAPAAPAQDSSAPHEPREQLSAPLINPGGTGGSGGAG
MSMEG_1870|M.smegmatis_MC2_155 GSAEHHRPVTDESRNWADEQAHRPAEQQPAHNAAAEQPVTHDRNSAETNE
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 DGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGE---------GWHR
Rv3903c|M.tuberculosis_H37Rv DGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGE---------GWHR
MMAR_3072|M.marinum_M GGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGTAHG---------TADG
MUL_2318|M.ulcerans_Agy99 GGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGTAHG---------TADG
MAV_2415|M.avium_104 GGHPPGEPPHGGKPSGDG----GPPDEDSHRDGTPGN---------GDDG
Mflv_3843|M.gilvum_PYR-GCK AVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPG
Mvan_2552|M.vanbaalenii_PYR-1 GVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPG
MAB_4317|M.abscessus_ATCC_1997 GIKPPKWSP--------------------------------------TDD
MLBr_02591|M.leprae_Br4923 GSRN----------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 SREPAYSSAVNGPQPAMGPMMSPGVGSGPGSPMTPHAPGPVHGGGESPSP
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 LSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQ
Rv3903c|M.tuberculosis_H37Rv LSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQ
MMAR_3072|M.marinum_M GDAHGDDVSGHGLSAEKRDEIIAMPKGSRPDPSEYLSPEYIQGHLDRFTD
MUL_2318|M.ulcerans_Agy99 GDAHGDDVSGHGLSAEKRDEIIAMRKGSRPDPSEYLSPEYIQGHLDRFTG
MAV_2415|M.avium_104 AAGEIDDGP-AGVDGQSTPAKVAGVDYPLPPSDALRVLEHPGAELQRLAD
Mflv_3843|M.gilvum_PYR-GCK VPAGGDAGVVTPPAPGVPGAPAATEAGLATPPGPGAPGAPVVGDAGVATP
Mvan_2552|M.vanbaalenii_PYR-1 VPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTP
MAB_4317|M.abscessus_ATCC_1997 YAQKWWDGTSQMYAESASGEVRAVIGSNLRPGNVWQTVELPRLMDNPHVN
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 AAKLPTPDTSTRGPETRPSHTGSPETPRAQQPSAVGPTPGSTPSAPVHSS
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 GQP-YTQERYQERFNSVGPWG----QQYSNFPPN--------NGAVPGTR
Rv3903c|M.tuberculosis_H37Rv GQP-YTQERYQERFNSVGPWG----QQYSNFPPN--------NGAVPGTR
MMAR_3072|M.marinum_M GATRFMPESNLDKYG-IAQRD----GTSFVMPKS--------EADAMIAG
MUL_2318|M.ulcerans_Agy99 GATRFMPESNLDKYG-IAQRD----GTSFVMPKS--------EADAMIAG
MAV_2415|M.avium_104 GG---VPSSILEGYEPLAGRSVDDFNREFTIETSNGERGWDWEAQAPENG
Mflv_3843|M.gilvum_PYR-GCK PGPGVPGAPIVDEAGLATPPAP-----VAPVEGAGGAVPPAGPPPAPVFG
Mvan_2552|M.vanbaalenii_PYR-1 PGPGAPGVPVVDEAGVVTPPAPPAAAPGAPIDAAAASVAPSGPPAAPVLG
MAB_4317|M.abscessus_ATCC_1997 RIVVIDPDTGIETTVFQR--------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 ADQSRQSAST-----------------------SPASSTSEQTAPKEHGT
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 IAYTNLEKFL-----------------------SDYGPQLDRIGGDQGKY
Rv3903c|M.tuberculosis_H37Rv IAYTNLEKFL-----------------------SDYGPQLDRIGGDQGKY
MMAR_3072|M.marinum_M TGG-------------------------------DLRLMEEELGLPEG-F
MUL_2318|M.ulcerans_Agy99 TGG-------------------------------DLRLMEEELGLPEG-F
MAV_2415|M.avium_104 FAGNPIESNH-----------------------IPAGLHFDRIGPNGGGF
Mflv_3843|M.gilvum_PYR-GCK DAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASG
Mvan_2552|M.vanbaalenii_PYR-1 EAGVVAPPAP-----------PGGGAPGGGAPGAGVG---TGAPIEGAAG
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 APGSSVPPSDSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSDLDYN
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 LAIMEHGRPASWEQR----ALHVTSLRDPY--------------------
Rv3903c|M.tuberculosis_H37Rv LAIMEHGRPASWEQR----ALHVTSLRDPY--------------------
MMAR_3072|M.marinum_M LDSNQIVRIDIEDPR----QFNLRIPSGNE--------------------
MUL_2318|M.ulcerans_Agy99 LDSNQIVRIDIEDPR----QFNLRIPSGNE--------------------
MAV_2415|M.avium_104 LSPEGVPLAERATPPGLAAQYHVFEGTGRE--------------------
Mflv_3843|M.gilvum_PYR-GCK AVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGGPVGGPGALPAPGAPIV
Mvan_2552|M.vanbaalenii_PYR-1 AGGVPAAPLAANAGAAT---PPAAATGG----------------AGAPID
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 PMLDENGHYVPGSLPSYDELLRLTRTEPDSAHYWSGRDANGVGVGPDGSG
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --HAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQN-EMRKVEEL
Rv3903c|M.tuberculosis_H37Rv --HAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQN-EMRKVEEL
MMAR_3072|M.marinum_M --AGANEQWIPG-------------GRLPTGASEAVVDGGK---IPQGDY
MUL_2318|M.ulcerans_Agy99 --AGANEQWIPG-------------GLLPTGASEAVVDGGK---VPQGDY
MAV_2415|M.avium_104 --IPAGKDWVVQHGPAKE-----AFGQPGGGDQWIVLDRATNRPVPVDEL
Mflv_3843|M.gilvum_PYR-GCK GEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGEAGVVTPPAPG
Mvan_2552|M.vanbaalenii_PYR-1 AAAGAAAPPAP----------------PAP---GAPIFGEAGVAAPPLPP
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 IAERIAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAAYAEN
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 IRRGVLRQ------------------------------------------
Rv3903c|M.tuberculosis_H37Rv IRRGVLRQ------------------------------------------
MMAR_3072|M.marinum_M TVTDVFEEK-----------------------------------------
MUL_2318|M.ulcerans_Agy99 TVTDVFEEK-----------------------------------------
MAV_2415|M.avium_104 IRRRLLREITPPNDKLAIGYRGS---------------------------
Mflv_3843|M.gilvum_PYR-GCK VPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGV
Mvan_2552|M.vanbaalenii_PYR-1 APGGAGAVPAGVVTPPVPGVPGGAGAVPAGAVTPPTP-------------
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 ARGDVTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRATELF
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK ATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGS
Mvan_2552|M.vanbaalenii_PYR-1 ---PVPGSSSGG--------------------------------------
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 HRTTSADGPAPNGQMEPTARHDGLTSETDSRTLRDTDQDSIDRASNKPDA
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK TDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGTPGSTLTLTDLLTPPGI
Mvan_2552|M.vanbaalenii_PYR-1 ---FVNYPAPPVPPTPPNSAGVNTGTPGSPIPGTPGSTLTISDLLTPPGV
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 DVRAEPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGPDGRYKISGHGDYH
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK ARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPGTPSPIAPLAATGLSN
Mvan_2552|M.vanbaalenii_PYR-1 ARTVQNTASSVMSIAPPGTPPVPGGAGSVSVGVPAPPSPLTPLAATGLSN
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 SGDGTFTVPADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTYYPGE
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK LVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQGDSAATPPAA
Mvan_2552|M.vanbaalenii_PYR-1 LVSPPSLTIPSIPGLPVPLPNEVPVPSDLLCVGTDWSATQGDSATTPVNA
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 TMPNYTLLPPDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLGSWNH
TH_3868|M.thermoresistible__bu --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3072|M.marinum_M --------------------------------------------------
MUL_2318|M.ulcerans_Agy99 --------------------------------------------------
MAV_2415|M.avium_104 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK EVPR-VVTGAAPTGDRRDRWGNR---------------------------
Mvan_2552|M.vanbaalenii_PYR-1 EIPRALVTGAAPVGDRRDRWDTR---------------------------
MAB_4317|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155 RVFDVHGIYHQDTYDFIEKYPWPEPENLGDDDW
TH_3868|M.thermoresistible__bu ---------------------------------
Mb3933c|M.bovis_AF2122/97 ---------------------------------
Rv3903c|M.tuberculosis_H37Rv ---------------------------------
MMAR_3072|M.marinum_M ---------------------------------
MUL_2318|M.ulcerans_Agy99 ---------------------------------
MAV_2415|M.avium_104 ---------------------------------
Mflv_3843|M.gilvum_PYR-GCK ---------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 ---------------------------------
MAB_4317|M.abscessus_ATCC_1997 ---------------------------------
MLBr_02591|M.leprae_Br4923 ---------------------------------