For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSLVDYILSLFRSEDAARSFVASSGQAMTNAGLVNVSPVEISSAAANALPFLNLGAGDPIGGLQQAVAD QYGLAPASEVGTASSYVAQDAGAVVAQDAAAVVSDAGVAAADAGFAGADIGASVANVVAADIGAGLASGL TSGLGAGLWSQSGLGWQTGVGGVVPGLAYTQATGDFGGQVGLASQVGLGFGAGIQAGFGAQASAGLGLGF GAQTGLGAQTGLGIGAGFEGGFAGQAGAGLGLGIGAQTGLGVGLGGQTAVGGGLGLGLGGGLGGQAGLGL GGGFGGAGEFGLGGGFVSQAGFDAQLGAQAGATVGAGIGGNAGLDVGGALGGQAGLGLGGGFVSQAGFDG QLGGQAGAGVGGQAGGAVGGSAGGAIGGGFGGGAGVGGQAGLGLGGGFVSQAGFDAQLGAQAGVGVGAGV GGQAGGAVGGSAGGAIGGGFGGGAGVGGQAGAAVGGSAGGAVGAGAGFGSRVVANGQVGAGGQVGGGIAG QAGGGIAGQAGGGIAGQAGLAGQAGIASQAGLAGQAGLAGQAGIASQAGLAGQAGIASQAGIASQAGIAS QAGLAAGGSAGIASQAGLGIGGQAALGGQAGAAVGGGLAGVGNVSGLTGIGGNASLGATGQAGLIASEGA ALNGAATPHVSGPLGGVGVGGQAGAAGGAGLGLGAGSRGSILSGDSTTLGGHPNPQPAALGAAGGTGIGA HSGAGGGMAAGLGGSVAGGAGAEAAGGFGGGTQIGGQAGLGGSAAGGAGTELGGTAGSPGAGMGAGVGGC THAGGQVGLGGGSTAGGQAGLGGGSTAGGSVGHGDILGQEGTTLGGNGGVSGGIPPVEHGPTIPTGQGPV IQGGGGAGAGAGGQVSPPSGNGPVIQSPGAGAGHGGANPPVINAPAPHVATPTPAHTPPVEHAPVVTPQP HVPAEQPAHHEPPSPSVFGHEPPVTHTPPVHVDPPSHGPVDPHGF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0579 | iniB | - | 100% (955) | membrane protein, IniB |
M. ulcerans Agy99 | MUL_4367 | - | e-108 | 36.56% (919) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_0572 | - | 5e-87 | 33.73% (925) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | 1e-107 | 36.19% (898) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 7e-92 | 38.42% (721) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 1e-108 | 37.05% (834) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 3e-08 | 45.35% (86) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 4e-63 | 36.04% (530) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_0614 | iniB | 0.0 | 91.00% (1011) | membrane protein, IniB |
M. avium 104 | MAV_4827 | - | 1e-15 | 39.63% (164) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-69 | 32.35% (810) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4332 | - | 2e-21 | 27.13% (446) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-92 | 37.29% (716) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0579|M.ulcerans_Agy99 ----------------------------------MTSLVDYILSLFRSED MMAR_0614|M.marinum_M --------------------------------MKMTSLVDYILSLFRSED Mb3538|M.bovis_AF2122/97 --------------------------------MSFVLIAPEFVTAAAG-- Rv3508|M.tuberculosis_H37Rv --------------------------------MSFVLIAPEFVTAAAG-- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------------MSIIDFILNLFRDPV MAV_4827|M.avium_104 -----------------------------MNIVLGVSMAPSSIQMVVLEG MLBr_01556|M.leprae_Br4923 -----------------------------MAGKARVHELAKELGVTSKEV MUL_0579|M.ulcerans_Agy99 AARSFVASSGQAMTNAGLVNVSPVEISSAAANALPFLNLG---------- MMAR_0614|M.marinum_M AARSFVASPGQAMTNAGLVNVSPVEISSAAANALPFLNLG---------- Mb3538|M.bovis_AF2122/97 DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQAIS Rv3508|M.tuberculosis_H37Rv DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQAIS Mflv_5091|M.gilvum_PYR-GCK -----------------------------------MVTFG---------- Mvan_1264|M.vanbaalenii_PYR-1 ----MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFG---------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASN---------- MAV_4827|M.avium_104 EYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREG---------- MLBr_01556|M.leprae_Br4923 LARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKG---------- MUL_0579|M.ulcerans_Agy99 ------------------AGDPIGGLQQAVADQYGLAPASEVG------- MMAR_0614|M.marinum_M ------------------AGDPIGGLQQAVADQYGLAPASEVG------- Mb3538|M.bovis_AF2122/97 AQVAAYHQRFVQALSTGAGAYASAEAAAAEQIVLGVINAPTQ-------- Rv3508|M.tuberculosis_H37Rv AQVAAYHQRFVQALSTGAGAYASAEAAAAEQIVLGVINAPTQ-------- Mflv_5091|M.gilvum_PYR-GCK ----------------GGATPTPTSLGAAAVDLSGTSCG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------GSGAPTPNNLAASLVDLSGTSCG----------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------YGYQSQWVNTGNPIHDLSGNLQNYYAAQ------ MAV_4827|M.avium_104 ------------------AADAGLQLSSIGVTWTDQLEAAALR------- MLBr_01556|M.leprae_Br4923 -------------AEQVATKAQAKRLGESLDQTLDRALDKAVAG------ MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 ------------------------------------------TASSYVAQ MMAR_0614|M.marinum_M ------------------------------------------AASSYVAQ Mb3538|M.bovis_AF2122/97 ----------------------------------ALLGRPLIGDGANATT Rv3508|M.tuberculosis_H37Rv ----------------------------------ALLGRPLIGDGANATT Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQ---- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQ---- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------P MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------NGATTAA MUL_0579|M.ulcerans_Agy99 DAGAVVAQDAAAVVSDAGVAAADAGFAGADIGASVANVVAADIGAGLASG MMAR_0614|M.marinum_M DAGAVVAQDAAAVVSDAGVAAADAGFAGADIGASVANVVAADIGAGLASG Mb3538|M.bovis_AF2122/97 PGGAGGAGGLLFGNGGAG-AAGAPGQAGGPGGPAGLWGNGGPGGAGGSGG Rv3508|M.tuberculosis_H37Rv PGGAGGAGGLLFGNGGAG-AAGAPGQAGGPGGPAGLWGNGGPGGAGGSGG Mflv_5091|M.gilvum_PYR-GCK -DGTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 -DGTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGG-NGGVGWAG TH_4332|M.thermoresistible__bu ---------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPRTVEYEY MAB_4284c|M.abscessus_ATCC_199 DGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNR MAV_4827|M.avium_104 DALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAV MLBr_01556|M.leprae_Br4923 PVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPA . MUL_0579|M.ulcerans_Agy99 LTSGLGAGLWSQSGLGWQTGVGGVVPGLAYTQATGDFG-GQVGLASQVGL MMAR_0614|M.marinum_M LTSGLGAGLWSQSGLGWQTGVGGVVPGLAYTQATGDFG-GQVGLASQVGL Mb3538|M.bovis_AF2122/97 GTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGA Rv3508|M.tuberculosis_H37Rv GTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGA Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAG-AFALFGNGGNGGNGG-VGVVGATG-----AVGAPGVAGA Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAG-LFSLFGRGGNGGNGG-VGIAGATG-----AVGAPGVAGA MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDG-------GTGGTGGT TH_4332|M.thermoresistible__bu SLVACDSTLPLMCEAGDSVG-------------------------GLGGA MAB_4284c|M.abscessus_ATCC_199 GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNS------------GPIAS MAV_4827|M.avium_104 VETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG---------LEKLESL MLBr_01556|M.leprae_Br4923 APHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPR MUL_0579|M.ulcerans_Agy99 GFGAGIQAG-----FGAQAS---AGLG-----LGFGAQTGLGAQTGLG-- MMAR_0614|M.marinum_M GFGAGIQAG-----FGAQAS---AGLG-----LGFGAQTGLGAQTGLG-- Mb3538|M.bovis_AF2122/97 GGGTGGAGGRAELLFGAGGA---GGAGGAGTDGGPGATGGTGGHGGVGGD Rv3508|M.tuberculosis_H37Rv GGGTGGAGGRAELLFGAGGA---GGAG---TDGGPGATGGTGGHGGVGGD Mflv_5091|M.gilvum_PYR-GCK TGATGVTSG----VVGGNGE---DAVG-------YGATGAAGAAGAAG-- Mvan_1264|M.vanbaalenii_PYR-1 TGATGVTSN----VTGGNGA---DAVG-------YGATGAAGAAGAAG-- MSMEG_0868|M.smegmatis_MC2_155 GGGTGGTGG-----IGGTGG---GLFG------LLGHSGSTGAAGAAGNG TH_4332|M.thermoresistible__bu SHDR-----------SAFSA---SALG----------------------- MAB_4284c|M.abscessus_ATCC_199 GQGSTAVNG------DVRDSNIIN-------------------------- MAV_4827|M.avium_104 PGGLLLVGS------GVDVAPLKQVLQ----------------------- MLBr_01556|M.leprae_Br4923 PSASPSSMSPRPGGAVGGGGPRPPRTG----------------------- MUL_0579|M.ulcerans_Agy99 ---IGAGFEGGFAGQAGAGLGLGIGAQTGLGVGLGGQTAVGGGLGLGLG- MMAR_0614|M.marinum_M ---IGAGFEGGFAGQAGAGLGLGIGAQTGLGVGLGGQTAVGGGLGLGLG- Mb3538|M.bovis_AF2122/97 GGWLAPGGAGGAGGQGGAG-GAGSDGGALGGTGGTGGTGGAGGAGGRGAL Rv3508|M.tuberculosis_H37Rv GGWLAPGGAGGAGGQGGAG-GAGSDGGALGGTGGTGGTGGAGGAGGRGAL Mflv_5091|M.gilvum_PYR-GCK ----AAGAAGAVGSAGAAG-EAGETG-TWGNAGLPGKAGDAGGAGAVG-- Mvan_1264|M.vanbaalenii_PYR-1 ----AAGKAGAVGSAGTAG-SAGAPG-VWGNAGLPGAAGAAGGAGAIG-- MSMEG_0868|M.smegmatis_MC2_155 ----GDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKG TH_4332|M.thermoresistible__bu --------------MASFGPDWNPGGAFLGLIGPGGLLIGDG-------- MAB_4284c|M.abscessus_ATCC_199 ---------------ADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS- MAV_4827|M.avium_104 ---------------TTTFLDVSVAEEPETALARGAALAAANAPLFASS- MLBr_01556|M.leprae_Br4923 -----VPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRP- . . MUL_0579|M.ulcerans_Agy99 -GGLGGQAGLGLGGGFGGAG------------EFGLGGGFVSQAGFDAQL MMAR_0614|M.marinum_M -GGLGGQAGLGLGGGFGGAG------------EFGLGGGFVSQAGFDAQL Mb3538|M.bovis_AF2122/97 LLGAGGQGGLGGAGGQGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAG Rv3508|M.tuberculosis_H37Rv LLGAGGQGGLGGAGGQGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAG Mflv_5091|M.gilvum_PYR-GCK --AAGAAGTVGTAGATGGTG-------------TGANGGAGGVGGVGGTG Mvan_1264|M.vanbaalenii_PYR-1 --TAGVAGAAGTAGATGGTG-------------VGGNGGAGQAGGIGGTG MSMEG_0868|M.smegmatis_MC2_155 GGGGGGGGGAILIGANGGTVDG------HAIGGNGGNGGNGSTTAAGGNG TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 --GGGGHGGGGRPGQRGGAAG----------------------------- MUL_0579|M.ulcerans_Agy99 G-----AQAGATVGAGIGGNAGLDVGGALG-------------------- MMAR_0614|M.marinum_M G-----AQAGATVGAGIGGNAGLDVGGALG-------------------- Mb3538|M.bovis_AF2122/97 GAAGQLFSAGGAAGAVGVGGTGGQGGAG---------------------- Rv3508|M.tuberculosis_H37Rv GAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLTGGTGFA Mflv_5091|M.gilvum_PYR-GCK -------AAGAAGGAGGLGETGTTGGAG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------AAGAAGQAGTAGETGVTGGVG---------------------- MSMEG_0868|M.smegmatis_MC2_155 -------GTGGTGRVIAEGTGSTAEGTATG-------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------VTVVDDHSQRNTTNINDSFN---------------------- MAV_4827|M.avium_104 --------TAALAYAQDPGTGAVDQYSLPD-------------------- MLBr_01556|M.leprae_Br4923 -------AFGRPGGAPRRGRKSKRQKRQEY-------------------- MUL_0579|M.ulcerans_Agy99 ---------------------------------------------GQAGL MMAR_0614|M.marinum_M ---------------------------------------------GQAGL Mb3538|M.bovis_AF2122/97 ----------------------------------GMGGSGADNASGIGAD Rv3508|M.tuberculosis_H37Rv GGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADNASGIGAD Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------------GVGGQ Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------------GIGGQ MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------GDGGH TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------TDRST MAV_4827|M.avium_104 ---------------------------------------------YLYVP MLBr_01556|M.leprae_Br4923 ---------------------------------------------DSMQA MUL_0579|M.ulcerans_Agy99 GLGGGFVSQAGFDGQLGGQAGAGVGGQAGGAVGGSAGGAIGGGFGGG--- MMAR_0614|M.marinum_M GLGGGFVSQAGFDGQLGGQAGVGVGGQAGGAVGGSAGGAIGGGFGGG--- Mb3538|M.bovis_AF2122/97 GGAGGTGGNAGAGGAGGAAGTGGTGGVVG--AAGKAGIGGTGGQGGA--- Rv3508|M.tuberculosis_H37Rv GGAGGTGGNAGAGGAGGAAGTGGTGGVVG--AAGKAGIGGTGGQGGA--- Mflv_5091|M.gilvum_PYR-GCK GTAGGTG---GVGGIGGAGSTGAVGGVGG--KGIQGGQGLQGGKGGD--- Mvan_1264|M.vanbaalenii_PYR-1 GTEGGTG---GVGGVGGVGATGGAGGVGG--KGIQGGQGLQGGQGGD--- MSMEG_0868|M.smegmatis_MC2_155 STGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGA--- TH_4332|M.thermoresistible__bu --LNGTDAYIDENGVFHEATRGGNGGLLWG-NGGKGGNGLDAGLYTVPDP MAB_4284c|M.abscessus_ATCC_199 NIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAGN--- MAV_4827|M.avium_104 VDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVG--- MLBr_01556|M.leprae_Br4923 PVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVT . . MUL_0579|M.ulcerans_Agy99 AGVG--------------------------------------------GQ MMAR_0614|M.marinum_M AGVGGAVGGSAGGAIGGGFGGGAGVGGQAGGSAGGAIGGGFGGGAGVGGQ Mb3538|M.bovis_AF2122/97 GGAG----------------------SAGTDATATGATGGTGFSGGAGGA Rv3508|M.tuberculosis_H37Rv GGAG----------------------SAGTDATATGATGGTGFSGGAGGA Mflv_5091|M.gilvum_PYR-GCK GGAG----------------------GKGGDADSMGSAGATGGKGGNGGN Mvan_1264|M.vanbaalenii_PYR-1 GGTG----------------------GTGGDATSMGEAGATGGKGGNGGN MSMEG_0868|M.smegmatis_MC2_155 GGMGEIYS------------------GADGEATGISAGGDGGSATGADSL TH_4332|M.thermoresistible__bu D------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------AGLAGN MAV_4827|M.avium_104 -----------------------------------------------SGL MLBr_01556|M.leprae_Br4923 ATQS------------------------VGDETLELLGSEMNYNVQVVSP MUL_0579|M.ulcerans_Agy99 AGLGLGGGFVSQAGFDAQLGAQAGVGVG-------------AGVGGQAG- MMAR_0614|M.marinum_M AGLGLGGGFVSQAGFEGQLGGQAGVGVG-------------AGVGGQAG- Mb3538|M.bovis_AF2122/97 GGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGAGGTGG- Rv3508|M.tuberculosis_H37Rv GGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGK Mflv_5091|M.gilvum_PYR-GCK GGRGGLFGKGGNAGNGADGGTGGAGGAG--------------GTGGTGG- Mvan_1264|M.vanbaalenii_PYR-1 GGRGSLFGRGGNAGNGGNGGTGGNGGNG--------------GTGGTGG- MSMEG_0868|M.smegmatis_MC2_155 GGRGGTSWVQAGYGPTTGGKASGTAKAG---------------HGGKAS- TH_4332|M.thermoresistible__bu -NPGSTIQMYFEASDGADGGRGG--------------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAG--------------------- MAV_4827|M.avium_104 AVVGISAVLALEIALAIGIRTTGTVALQP--------------------- MLBr_01556|M.leprae_Br4923 EDEDRELLEPFDLTYGEDQGDEDELQVRP--------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------A Rv3508|M.tuberculosis_H37Rv GGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------A Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------N MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------D TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 GAVGGSAGGAIGGGFGGGAGVGGQA---------GAAVGGSAGGAVGAG- MMAR_0614|M.marinum_M GAVGGSAGGAIGGGFGGGAGVGGQA---------GAAVGGSAGGAVGAG- Mb3538|M.bovis_AF2122/97 GGTGGTGGAAGAGGAGGAVGTGGTGGVVGDVGNAGIGGTGGKGGAGGTG- Rv3508|M.tuberculosis_H37Rv GGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGIGGAG---STGGTG---------GTGGTGGTGGTGGTG- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGIGGAG---STGGTG---------GTGGTGGTGGTGGTG- MSMEG_0868|M.smegmatis_MC2_155 GGKGGNGGDALVMAAG---ATGVAT---------GNTAIGGNGGAASAN- TH_4332|M.thermoresistible__bu -------------------------------------FLFGNGGDGGNG- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------NAGLAGNAGLAGNAG- MAV_4827|M.avium_104 -----------TPNQHLIVPTEQAP-----------APPPVQASAPQPK- MLBr_01556|M.leprae_Br4923 -PVVTVMGHVDHGKTRLLDTIRKAN----------VREAEAGGITQHIG- . MUL_0579|M.ulcerans_Agy99 ------------------AGFGSRVVANGQVGAGGQVGGGIAGQAGG--G MMAR_0614|M.marinum_M ------------------AGFGSRVVGNGQVGAGGQVGGGIAGQAGG--G Mb3538|M.bovis_AF2122/97 ----------------FAGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGG Rv3508|M.tuberculosis_H37Rv AGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGG Mflv_5091|M.gilvum_PYR-GCK -------------------GTGGTGGTGGTGGKGGTGGTGGAGGTGGDGG Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGTGGKGGTGGTGGDGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 ------------------GAVGGNGGFTNIAAIHGSITDSSATSGHGGAA TH_4332|M.thermoresistible__bu ---------------------GNVGGKNGADPVTATVAADKS-------- MAB_4284c|M.abscessus_ATCC_199 --------------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG MAV_4827|M.avium_104 --------------------ISVPEPVAAPKPLSPPVAAPLPAAPPPAAP MLBr_01556|M.leprae_Br4923 -------------------AYQVGVDLDGSERLITFIDTPGHEAFTAMRA MUL_0579|M.ulcerans_Agy99 IAGQAGGGIAGQAGLAGQAGIASQAGLAGQAGLAGQAGIASQAG------ MMAR_0614|M.marinum_M IAGQAG--------------IASQAGLAGQAGLAGQAGIASQAG------ Mb3538|M.bovis_AF2122/97 AGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVG Rv3508|M.tuberculosis_H37Rv TGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATG Mflv_5091|M.gilvum_PYR-GCK TGGTGG-----------TGGTGGTGGTGGTGGAG--DGTGGTG------- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGG-----------TGGTGGTGGTGGTGGAG--DGLGGTG------- MSMEG_0868|M.smegmatis_MC2_155 QGGNGG-----------NGGNGWVQAYDPNGPAGTTIDKGKAAG------ TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAG--------------LAGNAGLAGNAGLAGNAGLAGNAG------ MAV_4827|M.avium_104 PLPEAP-------------PIPAAPPVVPVPVVVPPVPVPVPVR------ MLBr_01556|M.leprae_Br4923 RGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKID----- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------L MMAR_0614|M.marinum_M -------------------------------------------------L Mb3538|M.bovis_AF2122/97 NAGIG-------------------------------------------GT Rv3508|M.tuberculosis_H37Rv SAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGA Mflv_5091|M.gilvum_PYR-GCK ------------------------------------------------GT Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------------GT MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------------------GN TH_4332|M.thermoresistible__bu ------------------------------------------------VA MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------L MAV_4827|M.avium_104 -------------------------------------------------I MLBr_01556|M.leprae_Br4923 -------------------------------------------------K MUL_0579|M.ulcerans_Agy99 AGQAGIASQAGIAS----------------------------------QA MMAR_0614|M.marinum_M AGQAGLAGQAGIAS----------------------------------QA Mb3538|M.bovis_AF2122/97 GGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAG----------------- Rv3508|M.tuberculosis_H37Rv GGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKA Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGQGGQG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGFGGQGGQG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGDGGFNGTGGATG------------------------------------ TH_4332|M.thermoresistible__bu GGNGGNGGRGGLLF------------------------------------ MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVAG------------------------------------ MAV_4827|M.avium_104 PVPDPVSPPQLLAP-----------------------------------P MLBr_01556|M.leprae_Br4923 EGADPAKIRGQLTEY----------------------------------- MUL_0579|M.ulcerans_Agy99 GIASQAGLAAGGSAGIASQAG--------LGIGGQAALGGQAG------- MMAR_0614|M.marinum_M GIASQSGLAAGGSAGIASQAG--------LGIGGQAALGGQAG------- Mb3538|M.bovis_AF2122/97 GEGGAGGNSGVGGTNGSGGAG---------GAGGKGGTGGAGGSGADNPT Rv3508|M.tuberculosis_H37Rv GDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSIN Mflv_5091|M.gilvum_PYR-GCK GTGGTGGQGGLGGGGGTGGQG---------GTGGTGGQGGTGG------- Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGQGGLGGVGGTGGTG---------GTGGTGGQGGTGG------- MSMEG_0868|M.smegmatis_MC2_155 GRGGDGAGASVWKANGQHSTG-------QTDTGGNGGRGGDGG------- TH_4332|M.thermoresistible__bu GLGGNGGNGGWSTTSYLDARG---------GNGGNGGLGGVLR------- MAB_4284c|M.abscessus_ATCC_199 -NAAVAGNAAVGGVLNTGVSG---------AIGGSSHVGGAIN------- MAV_4827|M.avium_104 RLSVPQPVQPPVRVPQPPSPP---------QVGGTVPQSPPQH------- MLBr_01556|M.leprae_Br4923 GLVAEDFGGDTMFIDISAKVG----------TNIEALLEAVLLT------ . MUL_0579|M.ulcerans_Agy99 -AAVGGGLAGVGNVSGLTGIG----------------------------- MMAR_0614|M.marinum_M -AAVGGGLAGVGNVSGLTGIG----------------------------- Mb3538|M.bovis_AF2122/97 GAGFAGGAGGTGGAAGAGGAG--------------GATGTGGTGGVVGAT Rv3508|M.tuberculosis_H37Rv ANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAA Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGTGGTGGAGGDG----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGTGGTGGAGGDG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 -TFVNAGANGNGGAGGAGGVS----------------------------- TH_4332|M.thermoresistible__bu ----PGGLLSLLLPSGAASEP----------------------------- MAB_4284c|M.abscessus_ATCC_199 -----ESLGGSGSVGGSTAVG----------------------------- MAV_4827|M.avium_104 --QTPPGEGTPPKPDGPGNYG----------------------------- MLBr_01556|M.leprae_Br4923 ----ADAALDLRANSGMEAQG----------------------------- . * MUL_0579|M.ulcerans_Agy99 ---GNASLGATGQAG-------------LIASEGAALNGAATPHVSGPLG MMAR_0614|M.marinum_M ---GNASLGATGQAG-------------LIASEGAALNGAATPHVSGPLG Mb3538|M.bovis_AF2122/97 GSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGING Rv3508|M.tuberculosis_H37Rv GKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGING Mflv_5091|M.gilvum_PYR-GCK ---GLGGLGGFGGSGG-------------TGGQGGLGGPGGSTG-----G Mvan_1264|M.vanbaalenii_PYR-1 ---GLGGLGGFGGVGG-------------TGGQGGQGGPGGSTG-----G MSMEG_0868|M.smegmatis_MC2_155 --EGEGGTGGHGGDGG-------------RGGDGALGGNGGTGGVG--LG TH_4332|M.thermoresistible__bu -------------------------------------------------G MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------G MAV_4827|M.avium_104 ------------------------------------------------GG MLBr_01556|M.leprae_Br4923 ----------------------------VAIEAHLDRGRGPVATVLVQRG * MUL_0579|M.ulcerans_Agy99 GVGVGG-----------------QAGAAGGAGLGLGAGSRGSILS----- MMAR_0614|M.marinum_M GVGVGG-----------------QAGAAGGAGLGLGAGSRGGILS----- Mb3538|M.bovis_AF2122/97 AGGAGGDGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGG----NAGVG Rv3508|M.tuberculosis_H37Rv AGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGG----NAGVG Mflv_5091|M.gilvum_PYR-GCK AGGAGG-----------------QAGTAGKGGLFGGSGSAG----KAGA- Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG-----------------QAGVAGKGGLFGGSGSAG----TAGV- MSMEG_0868|M.smegmatis_MC2_155 NGGKGG-----------------NGGNGGNGGTYVDPSHTG----AGGN- TH_4332|M.thermoresistible__bu GLFTGG--------------------NGGNGGLAIANHWVG--------- MAB_4284c|M.abscessus_ATCC_199 GAHTG-------------------VGGGVSTGVGVGSHVGG--------- MAV_4827|M.avium_104 HVPTPG-----------------AGGSGGSGGGHVPTPGAG--------- MLBr_01556|M.leprae_Br4923 TLRIGDS----------------VVAGDAYGRVRRMVDEHG--------- * MUL_0579|M.ulcerans_Agy99 -----------------GDSTTLGGHPNPQPAALGAAGGTGIGAHSG--- MMAR_0614|M.marinum_M -----------------GDSTTLGGHPNPQPAALGAAGGTGIGAHSG--- Mb3538|M.bovis_AF2122/97 LTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGAS Rv3508|M.tuberculosis_H37Rv LTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGAS Mflv_5091|M.gilvum_PYR-GCK ---------------TGAAGASGGKGAQGATGAQGATGAQGATGATG--- Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGASGASGGKGAQGATGAQGATGAQGATGATG--- MSMEG_0868|M.smegmatis_MC2_155 ----------------GGNGGAGRIRVNNGTATGTATGGNGGNGGNG--- TH_4332|M.thermoresistible__bu ----------------ITDGVPGPDDDAVSSSAYGGHGGHGAGPGSG--- MAB_4284c|M.abscessus_ATCC_199 ----------------------------GISESLGGSGSVGGSTAVG--- MAV_4827|M.avium_104 ----------------------GSGGSGGGHVPTPGTGGPGGTGGSG--- MLBr_01556|M.leprae_Br4923 --------------VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDED--- . * . MUL_0579|M.ulcerans_Agy99 -----AGGGMAAGLGGSVAG------------GAGAEAAGGFGGGTQIGG MMAR_0614|M.marinum_M -----AGGGMAAGLGGSAAGGAGVGLGGSAAGGAGAEAAGGFGGGTHIGG Mb3538|M.bovis_AF2122/97 TTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGGGG Rv3508|M.tuberculosis_H37Rv TTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGG Mflv_5091|M.gilvum_PYR-GCK -----AAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGSQGAAG Mvan_1264|M.vanbaalenii_PYR-1 -----ASGAQGSAGSAGSAGVAGSAGTTGAQGSAGTNGANGANGSQGAAG MSMEG_0868|M.smegmatis_MC2_155 ----DADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATN TH_4332|M.thermoresistible__bu ------GNGGSAVANSLGNAIAGNGGDAGRFVLIGPGGNGGNGGTGLXXX MAB_4284c|M.abscessus_ATCC_199 -------GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG MAV_4827|M.avium_104 ------GGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAGT MLBr_01556|M.leprae_Br4923 -----RIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLIL . MUL_0579|M.ulcerans_Agy99 QAGLGGSAAGGAGTELGGTAGSPGAGMG---------------------- MMAR_0614|M.marinum_M QAGLGGSAAGGAGTELGGTAGSPGAGMG---------------------- Mb3538|M.bovis_AF2122/97 FGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAGA Rv3508|M.tuberculosis_H37Rv FGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGA Mflv_5091|M.gilvum_PYR-GCK KAGATGTTGATGAAGEDGDAGSGGS------------------------- Mvan_1264|M.vanbaalenii_PYR-1 KAGATGTTGATGAAGDAGDPGSEAV------------------------- MSMEG_0868|M.smegmatis_MC2_155 GTGGAATIVAYNVVQANPQASGTAT------------------------- TH_4332|M.thermoresistible__bu PRPRRRRNHRRTRRRPNGRRPRPPPGR----------------------- MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVNTGVGVGSHVGGGIS------------------------- MAV_4827|M.avium_104 PGGGLGGFGGGHAPAPGGGLGGGGG------------------------- MLBr_01556|M.leprae_Br4923 KGDNAGTVEALEEALMGIQVDDEVALR----------------------- MUL_0579|M.ulcerans_Agy99 AGVGGCTHAGGQVGLGGG-----------STAGGQAGLGGGST------- MMAR_0614|M.marinum_M AGVGGGTHAGGQVGLGGG-----------STAGGQAGLGGGSS------- Mb3538|M.bovis_AF2122/97 GGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAG Rv3508|M.tuberculosis_H37Rv GGINGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAG Mflv_5091|M.gilvum_PYR-GCK -GIN--GGAGGAGGAGGE-----------GGEGGDGGKGGAGA------- Mvan_1264|M.vanbaalenii_PYR-1 -DIN--GGAGGAGGAGGE-----------GGEGGAGGAGGDGS------- MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGI------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGG----------AHTSAINDALGGSGS------- MAV_4827|M.avium_104 ---HAPAPGGGLGGFGGG-----------HSGGGLGGLGGGHK------- MLBr_01556|M.leprae_Br4923 ---VIDRGVGGITETNVN----------LASASDAIIIGFNVR------- MUL_0579|M.ulcerans_Agy99 -------------------AGGSVGHGDILGQE------------GTTLG MMAR_0614|M.marinum_M -------------------AGGSVGHGDILGQE------------GTTLG Mb3538|M.bovis_AF2122/97 VPGDGGIGG----------TGGAGGAGGAGGAGDAGADGDPSIDGGQGGA Rv3508|M.tuberculosis_H37Rv VPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGA Mflv_5091|M.gilvum_PYR-GCK -------------------EGGAGGGGGAGGS-------------GAGGA Mvan_1264|M.vanbaalenii_PYR-1 -------------------EGGAGGSGGAGGS-------------GTGGA MSMEG_0868|M.smegmatis_MC2_155 -------------------DGGLGGNGGDGVVN------------TTANA TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------VGGSTAVGG---------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------AEGKATELASREGVEIR--------------- MUL_0579|M.ulcerans_Agy99 GNGGVSGGIPPVEHG----PTIPTGQGPVIQGGGGAGAGAGGQVSPPSGN MMAR_0614|M.marinum_M GNGGVSGGIPPVEHG----PTIPTGQGPVIQGGGGAGAGAGGQVSPPSGN Mb3538|M.bovis_AF2122/97 GGHGGQGGKGGLNSTGLASAASGDGGNGG-AGGAGGNGGDGDGFIGGSGG Rv3508|M.tuberculosis_H37Rv GGHGGQGGKGGLNSTGLASAASGDGGNGG-AGGAGGNGGDGDGFIGGSGG Mflv_5091|M.gilvum_PYR-GCK GGAGGSGG---------------SGGSGG-SGGSGGAAGDSDD------- Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGG---------------SGGSGG-AGGSGGAAGDSD-------- MSMEG_0868|M.smegmatis_MC2_155 ANPGSATG-------------TATGGDGGKATGTASQGGNGGPSWVQSGY TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------GAHTSAINESMNSSINASHSSSM MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------YYLVIYQAIDDIEKALRGMLKPIYE MUL_0579|M.ulcerans_Agy99 GPVIQSPGAGAGHGGANPPVINAPAPHVATPTPAHTPPVEHAPVVTPQPH MMAR_0614|M.marinum_M GPVIQSPGAGAGHGGANPPVINAPAPHVATPTPAHTPPVEHAPVVTPQPH Mb3538|M.bovis_AF2122/97 TGGTGGDAGAGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGF Rv3508|M.tuberculosis_H37Rv TGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGF Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN---- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNL MUL_0579|M.ulcerans_Agy99 VPAEQPAHHEPPSPSVFGHEPPVTHTPPVHVDPPSHGPVDPHGF------ MMAR_0614|M.marinum_M VPAEQPAHHEPPSPSVFGHEPPVTHTPPVHVDPPSHGPVDPHGF------ Mb3538|M.bovis_AF2122/97 AGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGG Rv3508|M.tuberculosis_H37Rv AGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -TATGGDGGAATTAGATG--GAGGFSNIAAIHGAITDSTAISGHGG---- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA--- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 QGG------------GAGFGSGVAG------------------------- Rv3508|M.tuberculosis_H37Rv QGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSID Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------------------------AAGAGGNGGKG---- Rv3508|M.tuberculosis_H37Rv GGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFI Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -GDGGTGGTG---------------------------------------- Rv3508|M.tuberculosis_H37Rv GGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -GTNFAGGQGG------------------AGGRGGAGGNGANG------- Rv3508|M.tuberculosis_H37Rv DGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASE Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------------------------------AGNGGNGGKGADG------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------------------------VGDNAAGGDGGNGGA Rv3508|M.tuberculosis_H37Rv DPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------------------------------WVQAYDPAGPVGSKIANS TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAG Rv3508|M.tuberculosis_H37Rv GGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGG TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0614|M.marinum_M -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGG Rv3508|M.tuberculosis_H37Rv AGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGDG-SEPGPGGNGAGGAGGNGGTGGTTAGG-----SGNGGNGGNGGNG TH_4332|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_0579|M.ulcerans_Agy99 ----------------- MMAR_0614|M.marinum_M ----------------- Mb3538|M.bovis_AF2122/97 GTDGDDGNGGSPGTDGS Rv3508|M.tuberculosis_H37Rv GTDGDDGNGGSPGTDGS Mflv_5091|M.gilvum_PYR-GCK ----------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------- MSMEG_0868|M.smegmatis_MC2_155 GADGTPGTAGTTGANNP TH_4332|M.thermoresistible__bu ----------------- MAB_4284c|M.abscessus_ATCC_199 ----------------- MAV_4827|M.avium_104 ----------------- MLBr_01556|M.leprae_Br4923 -----------------