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M. bovis AF2122 / 97 Mb3933c (-)

annotation: hypothetical protein Mb3933c
coordinates: 4321853 - 4324393
length: 846

MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVA
RNGLCNLGDGVRMSAHNYSLAEAMSDVAGRAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG
MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLPEAGLIESAFADAYASTTAVVGQCH
QLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDAL
AAEITAVVSHAEAVITAMADHAGKQWDRFLHSNPVGVVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASI
DPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWTTNPNEALGKTVFDAATLALPGG
PLSKLGSKGRDILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGP
LPHSPTESKPPPVDRPAEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVE
SAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHA
PHREQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDP
QGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIME
HGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIR
RGVLRQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3933c--100% (846)hypothetical protein Mb3933c
M. bovis AF2122 / 97Mb3906-6e-1329.34% (167) hypothetical protein Mb3906
M. bovis AF2122 / 97Mb3909c-1e-1230.26% (195) hypothetical protein Mb3909c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3843-2e-1229.31% (232) hypothetical protein Mflv_3843
M. tuberculosis H37RvRv3903c-0.0100.00% (846) hypothetical protein Rv3903c
M. leprae Br4923MLBr_01556infB9e-0825.75% (299) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4296c-2e-1133.33% (186) hypothetical protein MAB_4296c
M. marinum MMMAR_5464-0.054.62% (650) ADP-ribosyltransferse
M. avium 104MAV_4644-1e-18052.33% (665) hypothetical protein MAV_4644
M. smegmatis MC2 155MSMEG_1870-9e-3725.67% (713) hypothetical protein MSMEG_1870
M. thermoresistible (build 8)TH_3868-1e-1725.64% (351) PUTATIVE putative conserved hypothetical protein
M. ulcerans Agy99MUL_2318-5e-6631.09% (727) hypothetical protein MUL_2318
M. vanbaalenii PYR-1Mvan_1118-6e-1727.47% (233) hypothetical protein Mvan_1118

CLUSTAL 2.0.9 multiple sequence alignment


Mb3933c|M.bovis_AF2122/97           ---------------------MAPLAVDPAALDSAG-GAVVAAGAGLGAV
Rv3903c|M.tuberculosis_H37Rv        ---------------------MAPLAVDPAALDSAG-GAVVAAGAGLGAV
MMAR_5464|M.marinum_M               ---------------------MAPLAVDPAALDGAG-AAVVAAGEGLEPV
MAV_4644|M.avium_104                ---------------------MAPLACDPTALDHAG-ATVVAAGESLGSV
MSMEG_1870|M.smegmatis_MC2_155      ---------MPSNSGGGGGVSGIRIEVDPQVLIRAG-ESMLSLGNQLDML
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           ---------------MGKNPGVAPLSVDPEALSGAG-SAVAAAGDALAAA
Mvan_1118|M.vanbaalenii_PYR-1       ---------------------MTVQDVDPDTFYAVG-KGLFEKAGKLYDA
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------MDVVLGVSMTPT
Mflv_3843|M.gilvum_PYR-GCK          -------MSRTKKSIVVVMMGSAGLFLSAPLLGPAA-NATPTRGGVPCVG
MLBr_01556|M.leprae_Br4923          MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES
                                                                                      

Mb3933c|M.bovis_AF2122/97           ISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG
Rv3903c|M.tuberculosis_H37Rv        ISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG
MMAR_5464|M.marinum_M               IASLSAVLAGCAGMAGDDPVGAAVGRGYDRAAAKVFSAMAATRNGLCSIG
MAV_4644|M.avium_104                ISTLTAALAGTSGMAGDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIG
MSMEG_1870|M.smegmatis_MC2_155      MGALGPMLS-SGIASGIDLAGLAMALDYGDLTQKFSNTLANGANTFKTVG
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           LSSLTTGFS---ANTGQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNG
Mvan_1118|M.vanbaalenii_PYR-1       FNVNVAILGDTAAMAGTDDTGTAWAASYDQRVGEILAAVNDLTRAMDNYG
MAB_4296c|M.abscessus_ATCC_199      TARLVLVEGAGADGRIVDTDTIVVSEGEGTTSEQVLSAIVGTRDGMLDGG
Mflv_3843|M.gilvum_PYR-GCK          ILQQIVTRPGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVP
MLBr_01556|M.leprae_Br4923          FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP
                                                                                      

Mb3933c|M.bovis_AF2122/97           ---------------------DGVRMSAHNYSLAEAMSDVAGRAAPLPAP
Rv3903c|M.tuberculosis_H37Rv        ---------------------DGVRMSAHNYSLAEAMSDVAGRAAPLPAP
MMAR_5464|M.marinum_M               ---------------------DGVRMSAHNYSLAEAMSDVTRRAAALPAP
MAV_4644|M.avium_104                ---------------------DGVRMSAHNYAVAEAMSDLAGRASALPAP
MSMEG_1870|M.smegmatis_MC2_155      ---------------------LRLQASGHNYANADAVSTIGGGAPTGGVK
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           ---------------------AKIQLSASNYSAAEAASTLGGGAGVLPAP
Mvan_1118|M.vanbaalenii_PYR-1       ---------------------GVVIQAGYNHAVAEHNATLGNTEPAPVKP
MAB_4296c|M.abscessus_ATCC_199      ---------------------HNLVSTGVVWS------------------
Mflv_3843|M.gilvum_PYR-GCK          GRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPAS
MLBr_01556|M.leprae_Br4923          ---------------------VQVDHSAAVVPIVAGEGPSTAHREELAPP
                                                                                      

Mb3933c|M.bovis_AF2122/97           -PPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG-MIWPNGDSTKLRAAA
Rv3903c|M.tuberculosis_H37Rv        -PPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG-MIWPNGDSTKLRAAA
MMAR_5464|M.marinum_M               -TLTTCIVAASAPSAVGTADSAPAGWGWIAPYIG-MIWPTGNLSKLRTAA
MAV_4644|M.avium_104                -QVTGPLTVGAPPSAVGHGSGAPAGWGWVAPSIG-MIWPTGDSAKLRAAA
MSMEG_1870|M.smegmatis_MC2_155      GKFDETKPVDARDSPSLSVVPPPPAWYLVGSFLGPTAWPSGNPAMLRLTA
TH_3868|M.thermoresistible__bu      --------------------------------------------MLRLTV
MUL_2318|M.ulcerans_Agy99           -SEPAQFTAPGAPGTLGSGVLAPALWSVVEAFVG-DLWPNGDVAGLHAAA
Mvan_1118|M.vanbaalenii_PYR-1       PEPVSAAGVLTAPPSAGGPGSGLLDNVGLMQQVG-VPVPDGDTAKVSKAG
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------DHAEAAELRDSL
Mflv_3843|M.gilvum_PYR-GCK          GATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGA
MLBr_01556|M.leprae_Br4923          AGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGN
                                                                                      

Mb3933c|M.bovis_AF2122/97           VAWRSAGTQFALTEIQSTAGPMGVIRAQQ-LPEAGLIESAFADAYASTTA
Rv3903c|M.tuberculosis_H37Rv        VAWRSAGTQFALTEIQSTAGPMGVIRAQQ-LPEAGLIESAFADAYASTTA
MMAR_5464|M.marinum_M               SEWTAEGTKFALVETQLTAGPLGAIRSQQ-LPESGLIERAFTDAYVSTTS
MAV_4644|M.avium_104                AAWATAGANFMAAETAAGGGTMAAIGAQQ-IPEGAAINKALADASSATAD
MSMEG_1870|M.smegmatis_MC2_155      AQWENLATGFSAVSNQVSG-SSTAVSTQK-IPEASQIAQAHADLADGVAD
TH_3868|M.thermoresistible__bu      AQWRNFAHGFAVFEPQLAP-VLAVVSAQN-TPETPAIVSGLDELARGISA
MUL_2318|M.ulcerans_Agy99           GHWRDFAAALNGVQGALNS-PKSVVAGQD-IPEGVQIQQVLSAIGSDLAG
Mvan_1118|M.vanbaalenii_PYR-1       EAWDRLATVYQTTTVAEGLGVDARAFRETRSPEVEYIVSDLDELRQATSA
MAB_4296c|M.abscessus_ATCC_199      ASRGIDGVEFFSALHAGGALAKAASSVTG----YDKSALLVIEPQTATLA
Mflv_3843|M.gilvum_PYR-GCK          PVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPP
MLBr_01556|M.leprae_Br4923          NPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPR
                                                                                      

Mb3933c|M.bovis_AF2122/97           VVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQ
Rv3903c|M.tuberculosis_H37Rv        VVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQ
MMAR_5464|M.marinum_M               VVGQCQTIAAQLDRYADQIDEVHAAILDLLARICDPLTGIKEVWEVLTGE
MAV_4644|M.avium_104                VARQCQTIAAQLNSYAAKVDQVHAAILDLLSRICDPLTGIKEVWDLLTDE
MSMEG_1870|M.smegmatis_MC2_155      LANQATNLAETLNTFADNVQETQDAIRRLLDRVASIDGIINTVKGIFTGD
TH_3868|M.thermoresistible__bu      LTDASVEVAREVEDFAATVQGTQDAIRRLVGRVS-ISGLFHTVKGILTGD
MUL_2318|M.ulcerans_Agy99           VGAQCRKLAGALDDFADEVADTQDAIRDLLDRFGSVSGLWNQVVAIFEGD
Mvan_1118|M.vanbaalenii_PYR-1       VLDGCAELAQSCRDYKAALDDLRSTLERILEDLAVELAAT----------
MAB_4296c|M.abscessus_ATCC_199      VVDSADGSIVGLASEPLITGVTSGVLANLVNPLKGKENAPDGVFLLGLGT
Mflv_3843|M.gilvum_PYR-GCK          APPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGG
MLBr_01556|M.leprae_Br4923          PGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGG
                                                                                      

Mb3933c|M.bovis_AF2122/97           DEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEA---------VI
Rv3903c|M.tuberculosis_H37Rv        DEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEA---------VI
MMAR_5464|M.marinum_M               DEDEIERIAHEIAAVVDHFAAEANALSAQFNAALVHADT---------VL
MAV_4644|M.avium_104                DEDEIKKIADDIRTVVDNFGREADTLGGQIEATVSAVAA---------AT
MSMEG_1870|M.smegmatis_MC2_155      ALDIIKEVVEDIRTLLGNFQRQVKAVGALLEELKNALND---------TV
TH_3868|M.thermoresistible__bu      GKDILREVARDVRTVLDNFQRQVKGVIGLLEELATLIGD---------AA
MUL_2318|M.ulcerans_Agy99           ALDEIKEIAEDIRAVLSNLGRQARAQQQLMQQGMQAIDG---------LV
Mvan_1118|M.vanbaalenii_PYR-1       -------VAIGVAASFVSFG--AGAVAATAKAAHSVTKF---------AR
MAB_4296c|M.abscessus_ATCC_199      DVSDLAESLGDAIALPVNSPDQPELALARGAALASAQEP---------DF
Mflv_3843|M.gilvum_PYR-GCK          APVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAP
MLBr_01556|M.leprae_Br4923          RPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAP--------VVG
                                                                                      

Mb3933c|M.bovis_AF2122/97           TAMADHAGKQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWD
Rv3903c|M.tuberculosis_H37Rv        TAMADHAGKQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWD
MMAR_5464|M.marinum_M               DTMARHAAREWDQFLHGNPVG---AIVDFAGQRLKGLGEAAWGLAETALT
MAV_4644|M.avium_104                ENMSHWAGKEWDHFLHGTPVG---RALNQVGQAFKGVGEEGWGFLKGLYE
MSMEG_1870|M.smegmatis_MC2_155      TKFQKWADKNLREILGDQVGG---AISDIIKFQTD----LSTGVLNGVIN
TH_3868|M.thermoresistible__bu      TAFQKWLRPNLVAVFGEQVGG---AMADRIELRTD----LGVGVVTGLIG
MUL_2318|M.ulcerans_Agy99           VGMQRYVRGQLTQLLGQDVGNPVATVFDTYTNTQEGVFKAAVGMVEGIEQ
Mvan_1118|M.vanbaalenii_PYR-1       IIAEAIGAWRISKNISKGVKS----AHDIAGVRTKLQRIKNLGRKNKPEE
MAB_4296c|M.abscessus_ATCC_199      EASTALLGQAYSLEGPTGTGFAHPDAVTESAGEANTELREFEDFDDQPAE
Mflv_3843|M.gilvum_PYR-GCK          APPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVT
MLBr_01556|M.leprae_Br4923          GVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQS
                                                                                      

Mb3933c|M.bovis_AF2122/97           LGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLI
Rv3903c|M.tuberculosis_H37Rv        LGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLI
MMAR_5464|M.marinum_M               YNQIRALLDPLGYARDVGSMAQGMAPLVGLGDDHAPSVLESWKQLGKEVT
MAV_4644|M.avium_104                VSPNRMLLDPVGYGKTMAGMVEGAGTLVGLGPDGVPGAFDAWKALGKDVT
MSMEG_1870|M.smegmatis_MC2_155      TVAGTVAFADFDTWKGLGETALAVI-------KDPSLIDDIGIAAGKEFF
TH_3868|M.thermoresistible__bu      TVTGVVALADADTWRGLANLALTVG-------PDPTKMPEILAEMGKTIV
MUL_2318|M.ulcerans_Agy99           LNPQRFLIDPQGAAETWKAMTKTGLIN---HLLNPEEAVAADKEMVKGLL
Mvan_1118|M.vanbaalenii_PYR-1       KPPAPTPPPPPGVPAGWTARPADNG---------MGTVYQQPGSLGNSNS
MAB_4296c|M.abscessus_ATCC_199      RKPFLLVGAPLLLVFGICSIALAVS---------LTVTVRSTVDQGPSSP
Mflv_3843|M.gilvum_PYR-GCK          PPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVV
MLBr_01556|M.leprae_Br4923          VGDETLELLGSEMNYNVQVVSPEDE--------DRELLEPFDLTYGEDQG
                                                                                      

Mb3933c|M.bovis_AF2122/97           HWDEWT-TNPNE-ALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLK
Rv3903c|M.tuberculosis_H37Rv        HWDEWT-TNPNE-ALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLK
MMAR_5464|M.marinum_M               HWDDWS-RSPGE-ALGKSEFDLANLFLPGGPISKAASKGRDLADGLQGLK
MAV_4644|M.avium_104                HWDEWG-SNPAE-ALGKSTFDVATLALPGGPLSKLGKFGHSAADALKGLK
MSMEG_1870|M.smegmatis_MC2_155      AWDQLTGENPGR-GIGEAGFNIAGLFVGG-PLSKGGTVAKGVNKVRRAFD
TH_3868|M.thermoresistible__bu      AWDKWSGENPGR-AAGEAIFNVGSFFT---PVG----VLGGTTRATTSLG
MUL_2318|M.ulcerans_Agy99           HLEDWRRDRPGL-GFGGNLFDVATLFVPGAGGAGAGAKGAAGAARAAEVG
Mvan_1118|M.vanbaalenii_PYR-1       MRIMEPGADPRY-PNGYVKFTN----------------------------
MAB_4296c|M.abscessus_ATCC_199      DRGVVQNPLPAE-APKQAAPPPSP--------------------------
Mflv_3843|M.gilvum_PYR-GCK          DEAGVVTPPAPG-GPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAP
MLBr_01556|M.leprae_Br4923          DEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQ
                                             .                                        

Mb3933c|M.bovis_AF2122/97           ERLEPTTPHLEPPATPP--------RPGPQPPRIEPPESGHP-APAPAAK
Rv3903c|M.tuberculosis_H37Rv        ERLEPTTPHLEPPATPP--------RPGPQPPRIEPPESGHP-APAPAAK
MMAR_5464|M.marinum_M               ARLRPNEMGEPNPLKRPD-----ASAAEHTPPSTMPQQEAKQPAAAPQPK
MAV_4644|M.avium_104                K---PPGVPKPPEVKPP--------AAPKAPDSGQPAPSGKPGPVAPSGK
MSMEG_1870|M.smegmatis_MC2_155      HADSPPLDLPGRHGLDGNDLSVTGSRVPEVPEIRQDGIPDSVINPAPSNR
TH_3868|M.thermoresistible__bu      RAAS----AFGRG---------VDARTPGIPGT---GIPGRGVEPAPS--
MUL_2318|M.ulcerans_Agy99           GEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKTGRGLTEDLANLGGD
Mvan_1118|M.vanbaalenii_PYR-1       ---------------------------EHNQPINLDGKPGTRADTHIPRN
MAB_4296c|M.abscessus_ATCC_199      --------------------------VEAPAPAVSPAPVQQVVAPAPQHN
Mflv_3843|M.gilvum_PYR-GCK          PAATPPSSGSVETFSPPAP-PAPGTGTNSTVEISTPPPPGTPGLPSEGST
MLBr_01556|M.leprae_Br4923          VGVDLDGSERLITFIDTPG-----HEAFTAMRARGAKATDIAILVVAADD
                                                                                      

Mb3933c|M.bovis_AF2122/97           -PAPVPANGP-----LPHSPTESKPPPVDRP--AEPVAPSSASAG-----
Rv3903c|M.tuberculosis_H37Rv        -PAPVPANGP-----LPHSPTESKPPPVDRP--AEPVAPSSASAG-----
MMAR_5464|M.marinum_M               -PLR-PSDGHG----LPHSPTESKAPPVDKPATGEPVKP-AGAQL-----
MAV_4644|M.avium_104                -PAPGPADGP-----LPHSPTESKPPAGGTPPAAEPPKPTAAPHS-----
MSMEG_1870|M.smegmatis_MC2_155      LDAPSNPGGPE----APVRPPEPPGPTTHNPGGTRPPGGGDGPPPESPHR
TH_3868|M.thermoresistible__bu      ------PAG---------RPPAQRADAGH--GGERAP-------------
MUL_2318|M.ulcerans_Agy99           LPKADPPVGGRPVALPPPKPAGAPIEPTPRPVESVPPGKPALEAPSG---
Mvan_1118|M.vanbaalenii_PYR-1       -------------------PDGTYPIPKGWP-------------------
MAB_4296c|M.abscessus_ATCC_199      -------------------PAPAPKQVAPAPVQAAPQAPAPAPEAP----
Mflv_3843|M.gilvum_PYR-GCK          TYTTPPTPEIT------LNPANSGIDIATPPAPGLPGAPLEATAN-----
MLBr_01556|M.leprae_Br4923          GVMPQTVEAIN-----HAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYG
                                                       .                              

Mb3933c|M.bovis_AF2122/97           -------QPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVES
Rv3903c|M.tuberculosis_H37Rv        -------QPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVES
MMAR_5464|M.marinum_M               -------GEAR--APGAAARGEKELPAQAEHS-EQINTPVSAPGP--VDG
MAV_4644|M.avium_104                -------GEPKPIATPPESVGKPVTPAPAEGAPAQPHEPVSARVPPTVPA
MSMEG_1870|M.smegmatis_MC2_155      PVGPADPGPTRGDAPPPHTPSTPEPSHPGSSSVGEPGIRGNPEPSHTPPS
TH_3868|M.thermoresistible__bu      -------------VEPPAHETVLDHIENTAGNLNNLGVR-NREDTEEQPS
MUL_2318|M.ulcerans_Agy99           -----APGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPGERLSPVTP
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      -------------APAAPAPVPEEQPAPVAPPPAVVPVPIPLFPPVWEPP
Mflv_3843|M.gilvum_PYR-GCK          -----ITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTTPDTP
MLBr_01556|M.leprae_Br4923          ------LVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANS
                                                                                      

Mb3933c|M.bovis_AF2122/97           APATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHD
Rv3903c|M.tuberculosis_H37Rv        APATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHD
MMAR_5464|M.marinum_M               SDLDPTPARPHTSRAAPASAMP----HLAGSRSTPSDVCG---------P
MAV_4644|M.avium_104                ADTPAPSAPAASMSAASGPPMPPTP-SLPEPASLPSGPSGDLPAETPPTA
MSMEG_1870|M.smegmatis_MC2_155      VDHTPQHAPEPATPAAQNDAPHTSAESNSTPTHQPSTSDAPASTHSPTQH
TH_3868|M.thermoresistible__bu      N-------------------------------------------------
MUL_2318|M.ulcerans_Agy99           HVGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRPAELS
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      RRQENPWWPDRDRPRYTPPAQTQQPPIISIPGLPP---------------
Mflv_3843|M.gilvum_PYR-GCK          GAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGAPANAAVD
MLBr_01556|M.leprae_Br4923          GMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVD
                                                                                      

Mb3933c|M.bovis_AF2122/97           GASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQY
Rv3903c|M.tuberculosis_H37Rv        GASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQY
MMAR_5464|M.marinum_M               NVVS-----EGGSPGGHSTPAALDEV-------GGAPGASAPGEYHGTGG
MAV_4644|M.avium_104                GIPH-----SGEPSAPSSVPPHFPDTPTHGLGDGGAHGPPESDPKNANGH
MSMEG_1870|M.smegmatis_MC2_155      IGGSVGGEHSAISSDSNIGSAEHHRPVTDESRNWADEQAHRPAEQQPAHN
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           APHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGT
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      ---------IGGGDSDRGSHGGSRGGSGRGGWGDDGDSRGGSDSGSRGGW
Mflv_3843|M.gilvum_PYR-GCK          VATPPAPGVPGAPVVG-EAAVTTPGAPGVPGVPAGGDAGVVTPPAPGVPG
MLBr_01556|M.leprae_Br4923          EHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARK
                                                                                      

Mb3933c|M.bovis_AF2122/97           GEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQE-RY
Rv3903c|M.tuberculosis_H37Rv        GEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQE-RY
MMAR_5464|M.marinum_M               GPGDHGTADGGQSLIIVDGLHADDLSALADYTGSGYLDLNNALRSDI-LD
MAV_4644|M.avium_104                GPHDASLDSGSDHHLPLHPLDSDDLAALAHYTGPGYQELNFALREGA-LD
MSMEG_1870|M.smegmatis_MC2_155      AAAEQPVTHDRNSAETNESREPAYSSAVNGPQPAMGPMMSPGVGSGP-GS
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           AHGTADGGDAHGDDVSGHGLSAEKRDEIIAMRKGSRPDPSEYLSPEY-IQ
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      GDNGGSRGGWGDSGSSRGGSDSGSRGGWGGNSGSHGGGSGGGSNSGF-PW
Mflv_3843|M.gilvum_PYR-GCK          APVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGL-AT
MLBr_01556|M.leprae_Br4923          RNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQ
                                                                                      

Mb3933c|M.bovis_AF2122/97           QERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIG
Rv3903c|M.tuberculosis_H37Rv        QERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIG
MMAR_5464|M.marinum_M               ASLNARVAALNSALQKLPTYDGTVVRGTDLPPEVVAQYLPGEVITEVAFL
MAV_4644|M.avium_104                VSQQARVDALQKALEKLPVYEGAVVRGTNLPADVLEQYRPGEVITEAAFT
MSMEG_1870|M.smegmatis_MC2_155      PMTPHAPGPVHGGGESPSPAAKLPTPDTSTRGPETRPSHTGSPETPRAQQ
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           GHLDRFTGGATRFMPESNLDKYGIAQRDGTSFVMPKSEADAMIAGTGGDL
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      PFGGR---------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          PPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPVAPVEGAG
MLBr_01556|M.leprae_Br4923          VDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASRE
                                                                                      

Mb3933c|M.bovis_AF2122/97           GDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSE
Rv3903c|M.tuberculosis_H37Rv        GDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSE
MMAR_5464|M.marinum_M               STTTDPAVAQSPTFAGNVEFRIVSRTGR----DVSSVSMFPD-----ERE
MAV_4644|M.avium_104                STSTDHTVAQSSAFAGNTEFRIWSTTGR----DVSSVSMYPD-----EKE
MSMEG_1870|M.smegmatis_MC2_155      PSAVGPTPGSTPSAPVHSSADQSRQSASTSPASSTSEQTAPKEHGTAPGS
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           RLMEEELGLPEGFLDSNQIVRIDIEDPRQFNLRIPSGNEAGANEQWIPGG
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          GAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGGG
MLBr_01556|M.leprae_Br4923          GVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGI
                                                                                      

Mb3933c|M.bovis_AF2122/97           VAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ-------------
Rv3903c|M.tuberculosis_H37Rv        VAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ-------------
MMAR_5464|M.marinum_M               ILFPAG-TKFYVIDKTLDALTG-RTIIDMIER------------------
MAV_4644|M.avium_104                ILFPAG-SKFYVVSKTVDPQTG-RTIIEMIER------------------
MSMEG_1870|M.smegmatis_MC2_155      SVPPSDSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSDLDYNPMLD
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           LLPTGASEAVVDGGKVPQGDYTVTDVFEEK--------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          AGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGGP
MLBr_01556|M.leprae_Br4923          IAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFE
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      ENGHYVPGSLPSYDELLRLTRTEPDSAHYWSGRDANGVGVGPDGSGIAER
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          VGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGA
MLBr_01556|M.leprae_Br4923          CGMTLGYSDIKEGDVIESYELVEKQRA-----------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      IAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAAYAENARGD
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          PVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPP
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      VTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRATELFHRTT
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          APGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTVP
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      SADGPAPNGQMEPTARHDGLTSETDSRTLRDTDQDSIDRASNKPDADVRA
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          GNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGTP
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      EPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGPDGRYKISGHGDYHSGDG
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          GSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPG
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      TFTVPADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTYYPGETMPN
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          TPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGTD
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           --------------------------------------------------
Rv3903c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5464|M.marinum_M               --------------------------------------------------
MAV_4644|M.avium_104                --------------------------------------------------
MSMEG_1870|M.smegmatis_MC2_155      YTLLPPDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLGSWNHRVFD
TH_3868|M.thermoresistible__bu      --------------------------------------------------
MUL_2318|M.ulcerans_Agy99           --------------------------------------------------
Mvan_1118|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK          WSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR-------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3933c|M.bovis_AF2122/97           -----------------------------
Rv3903c|M.tuberculosis_H37Rv        -----------------------------
MMAR_5464|M.marinum_M               -----------------------------
MAV_4644|M.avium_104                -----------------------------
MSMEG_1870|M.smegmatis_MC2_155      VHGIYHQDTYDFIEKYPWPEPENLGDDDW
TH_3868|M.thermoresistible__bu      -----------------------------
MUL_2318|M.ulcerans_Agy99           -----------------------------
Mvan_1118|M.vanbaalenii_PYR-1       -----------------------------
MAB_4296c|M.abscessus_ATCC_199      -----------------------------
Mflv_3843|M.gilvum_PYR-GCK          -----------------------------
MLBr_01556|M.leprae_Br4923          -----------------------------