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MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVA RNGLCNLGDGVRMSAHNYSLAEAMSDVAGRAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLPEAGLIESAFADAYASTTAVVGQCH QLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDAL AAEITAVVSHAEAVITAMADHAGKQWDRFLHSNPVGVVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASI DPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWTTNPNEALGKTVFDAATLALPGG PLSKLGSKGRDILAGVRGLKERLEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAPAPAAKPAPVPANGP LPHSPTESKPPPVDRPAEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVE SAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHA PHREQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDP QGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIME HGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIR RGVLRQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3933c | - | - | 100% (846) | hypothetical protein Mb3933c |
M. bovis AF2122 / 97 | Mb3906 | - | 6e-13 | 29.34% (167) | hypothetical protein Mb3906 |
M. bovis AF2122 / 97 | Mb3909c | - | 1e-12 | 30.26% (195) | hypothetical protein Mb3909c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3843 | - | 2e-12 | 29.31% (232) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv3903c | - | 0.0 | 100.00% (846) | hypothetical protein Rv3903c |
M. leprae Br4923 | MLBr_01556 | infB | 9e-08 | 25.75% (299) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4296c | - | 2e-11 | 33.33% (186) | hypothetical protein MAB_4296c |
M. marinum M | MMAR_5464 | - | 0.0 | 54.62% (650) | ADP-ribosyltransferse |
M. avium 104 | MAV_4644 | - | 1e-180 | 52.33% (665) | hypothetical protein MAV_4644 |
M. smegmatis MC2 155 | MSMEG_1870 | - | 9e-37 | 25.67% (713) | hypothetical protein MSMEG_1870 |
M. thermoresistible (build 8) | TH_3868 | - | 1e-17 | 25.64% (351) | PUTATIVE putative conserved hypothetical protein |
M. ulcerans Agy99 | MUL_2318 | - | 5e-66 | 31.09% (727) | hypothetical protein MUL_2318 |
M. vanbaalenii PYR-1 | Mvan_1118 | - | 6e-17 | 27.47% (233) | hypothetical protein Mvan_1118 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3933c|M.bovis_AF2122/97 ---------------------MAPLAVDPAALDSAG-GAVVAAGAGLGAV Rv3903c|M.tuberculosis_H37Rv ---------------------MAPLAVDPAALDSAG-GAVVAAGAGLGAV MMAR_5464|M.marinum_M ---------------------MAPLAVDPAALDGAG-AAVVAAGEGLEPV MAV_4644|M.avium_104 ---------------------MAPLACDPTALDHAG-ATVVAAGESLGSV MSMEG_1870|M.smegmatis_MC2_155 ---------MPSNSGGGGGVSGIRIEVDPQVLIRAG-ESMLSLGNQLDML TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 ---------------MGKNPGVAPLSVDPEALSGAG-SAVAAAGDALAAA Mvan_1118|M.vanbaalenii_PYR-1 ---------------------MTVQDVDPDTFYAVG-KGLFEKAGKLYDA MAB_4296c|M.abscessus_ATCC_199 --------------------------------------MDVVLGVSMTPT Mflv_3843|M.gilvum_PYR-GCK -------MSRTKKSIVVVMMGSAGLFLSAPLLGPAA-NATPTRGGVPCVG MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES Mb3933c|M.bovis_AF2122/97 ISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG Rv3903c|M.tuberculosis_H37Rv ISSLTAALAGCAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG MMAR_5464|M.marinum_M IASLSAVLAGCAGMAGDDPVGAAVGRGYDRAAAKVFSAMAATRNGLCSIG MAV_4644|M.avium_104 ISTLTAALAGTSGMAGDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIG MSMEG_1870|M.smegmatis_MC2_155 MGALGPMLS-SGIASGIDLAGLAMALDYGDLTQKFSNTLANGANTFKTVG TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 LSSLTTGFS---ANTGQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNG Mvan_1118|M.vanbaalenii_PYR-1 FNVNVAILGDTAAMAGTDDTGTAWAASYDQRVGEILAAVNDLTRAMDNYG MAB_4296c|M.abscessus_ATCC_199 TARLVLVEGAGADGRIVDTDTIVVSEGEGTTSEQVLSAIVGTRDGMLDGG Mflv_3843|M.gilvum_PYR-GCK ILQQIVTRPGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVP MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP Mb3933c|M.bovis_AF2122/97 ---------------------DGVRMSAHNYSLAEAMSDVAGRAAPLPAP Rv3903c|M.tuberculosis_H37Rv ---------------------DGVRMSAHNYSLAEAMSDVAGRAAPLPAP MMAR_5464|M.marinum_M ---------------------DGVRMSAHNYSLAEAMSDVTRRAAALPAP MAV_4644|M.avium_104 ---------------------DGVRMSAHNYAVAEAMSDLAGRASALPAP MSMEG_1870|M.smegmatis_MC2_155 ---------------------LRLQASGHNYANADAVSTIGGGAPTGGVK TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 ---------------------AKIQLSASNYSAAEAASTLGGGAGVLPAP Mvan_1118|M.vanbaalenii_PYR-1 ---------------------GVVIQAGYNHAVAEHNATLGNTEPAPVKP MAB_4296c|M.abscessus_ATCC_199 ---------------------HNLVSTGVVWS------------------ Mflv_3843|M.gilvum_PYR-GCK GRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPAS MLBr_01556|M.leprae_Br4923 ---------------------VQVDHSAAVVPIVAGEGPSTAHREELAPP Mb3933c|M.bovis_AF2122/97 -PPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG-MIWPNGDSTKLRAAA Rv3903c|M.tuberculosis_H37Rv -PPSGCVGVGAPPSAVGGGGGAPKGWGWVAPYIG-MIWPNGDSTKLRAAA MMAR_5464|M.marinum_M -TLTTCIVAASAPSAVGTADSAPAGWGWIAPYIG-MIWPTGNLSKLRTAA MAV_4644|M.avium_104 -QVTGPLTVGAPPSAVGHGSGAPAGWGWVAPSIG-MIWPTGDSAKLRAAA MSMEG_1870|M.smegmatis_MC2_155 GKFDETKPVDARDSPSLSVVPPPPAWYLVGSFLGPTAWPSGNPAMLRLTA TH_3868|M.thermoresistible__bu --------------------------------------------MLRLTV MUL_2318|M.ulcerans_Agy99 -SEPAQFTAPGAPGTLGSGVLAPALWSVVEAFVG-DLWPNGDVAGLHAAA Mvan_1118|M.vanbaalenii_PYR-1 PEPVSAAGVLTAPPSAGGPGSGLLDNVGLMQQVG-VPVPDGDTAKVSKAG MAB_4296c|M.abscessus_ATCC_199 --------------------------------------DHAEAAELRDSL Mflv_3843|M.gilvum_PYR-GCK GATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGA MLBr_01556|M.leprae_Br4923 AGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGN Mb3933c|M.bovis_AF2122/97 VAWRSAGTQFALTEIQSTAGPMGVIRAQQ-LPEAGLIESAFADAYASTTA Rv3903c|M.tuberculosis_H37Rv VAWRSAGTQFALTEIQSTAGPMGVIRAQQ-LPEAGLIESAFADAYASTTA MMAR_5464|M.marinum_M SEWTAEGTKFALVETQLTAGPLGAIRSQQ-LPESGLIERAFTDAYVSTTS MAV_4644|M.avium_104 AAWATAGANFMAAETAAGGGTMAAIGAQQ-IPEGAAINKALADASSATAD MSMEG_1870|M.smegmatis_MC2_155 AQWENLATGFSAVSNQVSG-SSTAVSTQK-IPEASQIAQAHADLADGVAD TH_3868|M.thermoresistible__bu AQWRNFAHGFAVFEPQLAP-VLAVVSAQN-TPETPAIVSGLDELARGISA MUL_2318|M.ulcerans_Agy99 GHWRDFAAALNGVQGALNS-PKSVVAGQD-IPEGVQIQQVLSAIGSDLAG Mvan_1118|M.vanbaalenii_PYR-1 EAWDRLATVYQTTTVAEGLGVDARAFRETRSPEVEYIVSDLDELRQATSA MAB_4296c|M.abscessus_ATCC_199 ASRGIDGVEFFSALHAGGALAKAASSVTG----YDKSALLVIEPQTATLA Mflv_3843|M.gilvum_PYR-GCK PVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPP MLBr_01556|M.leprae_Br4923 NPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPR Mb3933c|M.bovis_AF2122/97 VVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQ Rv3903c|M.tuberculosis_H37Rv VVGQCHQLAAQLDAYAARIDAVHAAVLDLLARICDPLTGIKEVWEFLTDQ MMAR_5464|M.marinum_M VVGQCQTIAAQLDRYADQIDEVHAAILDLLARICDPLTGIKEVWEVLTGE MAV_4644|M.avium_104 VARQCQTIAAQLNSYAAKVDQVHAAILDLLSRICDPLTGIKEVWDLLTDE MSMEG_1870|M.smegmatis_MC2_155 LANQATNLAETLNTFADNVQETQDAIRRLLDRVASIDGIINTVKGIFTGD TH_3868|M.thermoresistible__bu LTDASVEVAREVEDFAATVQGTQDAIRRLVGRVS-ISGLFHTVKGILTGD MUL_2318|M.ulcerans_Agy99 VGAQCRKLAGALDDFADEVADTQDAIRDLLDRFGSVSGLWNQVVAIFEGD Mvan_1118|M.vanbaalenii_PYR-1 VLDGCAELAQSCRDYKAALDDLRSTLERILEDLAVELAAT---------- MAB_4296c|M.abscessus_ATCC_199 VVDSADGSIVGLASEPLITGVTSGVLANLVNPLKGKENAPDGVFLLGLGT Mflv_3843|M.gilvum_PYR-GCK APPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGG MLBr_01556|M.leprae_Br4923 PGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGG Mb3933c|M.bovis_AF2122/97 DEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEA---------VI Rv3903c|M.tuberculosis_H37Rv DEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEA---------VI MMAR_5464|M.marinum_M DEDEIERIAHEIAAVVDHFAAEANALSAQFNAALVHADT---------VL MAV_4644|M.avium_104 DEDEIKKIADDIRTVVDNFGREADTLGGQIEATVSAVAA---------AT MSMEG_1870|M.smegmatis_MC2_155 ALDIIKEVVEDIRTLLGNFQRQVKAVGALLEELKNALND---------TV TH_3868|M.thermoresistible__bu GKDILREVARDVRTVLDNFQRQVKGVIGLLEELATLIGD---------AA MUL_2318|M.ulcerans_Agy99 ALDEIKEIAEDIRAVLSNLGRQARAQQQLMQQGMQAIDG---------LV Mvan_1118|M.vanbaalenii_PYR-1 -------VAIGVAASFVSFG--AGAVAATAKAAHSVTKF---------AR MAB_4296c|M.abscessus_ATCC_199 DVSDLAESLGDAIALPVNSPDQPELALARGAALASAQEP---------DF Mflv_3843|M.gilvum_PYR-GCK APVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAP MLBr_01556|M.leprae_Br4923 RPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAP--------VVG Mb3933c|M.bovis_AF2122/97 TAMADHAGKQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWD Rv3903c|M.tuberculosis_H37Rv TAMADHAGKQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWD MMAR_5464|M.marinum_M DTMARHAAREWDQFLHGNPVG---AIVDFAGQRLKGLGEAAWGLAETALT MAV_4644|M.avium_104 ENMSHWAGKEWDHFLHGTPVG---RALNQVGQAFKGVGEEGWGFLKGLYE MSMEG_1870|M.smegmatis_MC2_155 TKFQKWADKNLREILGDQVGG---AISDIIKFQTD----LSTGVLNGVIN TH_3868|M.thermoresistible__bu TAFQKWLRPNLVAVFGEQVGG---AMADRIELRTD----LGVGVVTGLIG MUL_2318|M.ulcerans_Agy99 VGMQRYVRGQLTQLLGQDVGNPVATVFDTYTNTQEGVFKAAVGMVEGIEQ Mvan_1118|M.vanbaalenii_PYR-1 IIAEAIGAWRISKNISKGVKS----AHDIAGVRTKLQRIKNLGRKNKPEE MAB_4296c|M.abscessus_ATCC_199 EASTALLGQAYSLEGPTGTGFAHPDAVTESAGEANTELREFEDFDDQPAE Mflv_3843|M.gilvum_PYR-GCK APPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVT MLBr_01556|M.leprae_Br4923 GVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQS Mb3933c|M.bovis_AF2122/97 LGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLI Rv3903c|M.tuberculosis_H37Rv LGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLI MMAR_5464|M.marinum_M YNQIRALLDPLGYARDVGSMAQGMAPLVGLGDDHAPSVLESWKQLGKEVT MAV_4644|M.avium_104 VSPNRMLLDPVGYGKTMAGMVEGAGTLVGLGPDGVPGAFDAWKALGKDVT MSMEG_1870|M.smegmatis_MC2_155 TVAGTVAFADFDTWKGLGETALAVI-------KDPSLIDDIGIAAGKEFF TH_3868|M.thermoresistible__bu TVTGVVALADADTWRGLANLALTVG-------PDPTKMPEILAEMGKTIV MUL_2318|M.ulcerans_Agy99 LNPQRFLIDPQGAAETWKAMTKTGLIN---HLLNPEEAVAADKEMVKGLL Mvan_1118|M.vanbaalenii_PYR-1 KPPAPTPPPPPGVPAGWTARPADNG---------MGTVYQQPGSLGNSNS MAB_4296c|M.abscessus_ATCC_199 RKPFLLVGAPLLLVFGICSIALAVS---------LTVTVRSTVDQGPSSP Mflv_3843|M.gilvum_PYR-GCK PPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVV MLBr_01556|M.leprae_Br4923 VGDETLELLGSEMNYNVQVVSPEDE--------DRELLEPFDLTYGEDQG Mb3933c|M.bovis_AF2122/97 HWDEWT-TNPNE-ALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLK Rv3903c|M.tuberculosis_H37Rv HWDEWT-TNPNE-ALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLK MMAR_5464|M.marinum_M HWDDWS-RSPGE-ALGKSEFDLANLFLPGGPISKAASKGRDLADGLQGLK MAV_4644|M.avium_104 HWDEWG-SNPAE-ALGKSTFDVATLALPGGPLSKLGKFGHSAADALKGLK MSMEG_1870|M.smegmatis_MC2_155 AWDQLTGENPGR-GIGEAGFNIAGLFVGG-PLSKGGTVAKGVNKVRRAFD TH_3868|M.thermoresistible__bu AWDKWSGENPGR-AAGEAIFNVGSFFT---PVG----VLGGTTRATTSLG MUL_2318|M.ulcerans_Agy99 HLEDWRRDRPGL-GFGGNLFDVATLFVPGAGGAGAGAKGAAGAARAAEVG Mvan_1118|M.vanbaalenii_PYR-1 MRIMEPGADPRY-PNGYVKFTN---------------------------- MAB_4296c|M.abscessus_ATCC_199 DRGVVQNPLPAE-APKQAAPPPSP-------------------------- Mflv_3843|M.gilvum_PYR-GCK DEAGVVTPPAPG-GPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAP MLBr_01556|M.leprae_Br4923 DEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQ . Mb3933c|M.bovis_AF2122/97 ERLEPTTPHLEPPATPP--------RPGPQPPRIEPPESGHP-APAPAAK Rv3903c|M.tuberculosis_H37Rv ERLEPTTPHLEPPATPP--------RPGPQPPRIEPPESGHP-APAPAAK MMAR_5464|M.marinum_M ARLRPNEMGEPNPLKRPD-----ASAAEHTPPSTMPQQEAKQPAAAPQPK MAV_4644|M.avium_104 K---PPGVPKPPEVKPP--------AAPKAPDSGQPAPSGKPGPVAPSGK MSMEG_1870|M.smegmatis_MC2_155 HADSPPLDLPGRHGLDGNDLSVTGSRVPEVPEIRQDGIPDSVINPAPSNR TH_3868|M.thermoresistible__bu RAAS----AFGRG---------VDARTPGIPGT---GIPGRGVEPAPS-- MUL_2318|M.ulcerans_Agy99 GEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKTGRGLTEDLANLGGD Mvan_1118|M.vanbaalenii_PYR-1 ---------------------------EHNQPINLDGKPGTRADTHIPRN MAB_4296c|M.abscessus_ATCC_199 --------------------------VEAPAPAVSPAPVQQVVAPAPQHN Mflv_3843|M.gilvum_PYR-GCK PAATPPSSGSVETFSPPAP-PAPGTGTNSTVEISTPPPPGTPGLPSEGST MLBr_01556|M.leprae_Br4923 VGVDLDGSERLITFIDTPG-----HEAFTAMRARGAKATDIAILVVAADD Mb3933c|M.bovis_AF2122/97 -PAPVPANGP-----LPHSPTESKPPPVDRP--AEPVAPSSASAG----- Rv3903c|M.tuberculosis_H37Rv -PAPVPANGP-----LPHSPTESKPPPVDRP--AEPVAPSSASAG----- MMAR_5464|M.marinum_M -PLR-PSDGHG----LPHSPTESKAPPVDKPATGEPVKP-AGAQL----- MAV_4644|M.avium_104 -PAPGPADGP-----LPHSPTESKPPAGGTPPAAEPPKPTAAPHS----- MSMEG_1870|M.smegmatis_MC2_155 LDAPSNPGGPE----APVRPPEPPGPTTHNPGGTRPPGGGDGPPPESPHR TH_3868|M.thermoresistible__bu ------PAG---------RPPAQRADAGH--GGERAP------------- MUL_2318|M.ulcerans_Agy99 LPKADPPVGGRPVALPPPKPAGAPIEPTPRPVESVPPGKPALEAPSG--- Mvan_1118|M.vanbaalenii_PYR-1 -------------------PDGTYPIPKGWP------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------PAPAPKQVAPAPVQAAPQAPAPAPEAP---- Mflv_3843|M.gilvum_PYR-GCK TYTTPPTPEIT------LNPANSGIDIATPPAPGLPGAPLEATAN----- MLBr_01556|M.leprae_Br4923 GVMPQTVEAIN-----HAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYG . Mb3933c|M.bovis_AF2122/97 -------QPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVES Rv3903c|M.tuberculosis_H37Rv -------QPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVES MMAR_5464|M.marinum_M -------GEAR--APGAAARGEKELPAQAEHS-EQINTPVSAPGP--VDG MAV_4644|M.avium_104 -------GEPKPIATPPESVGKPVTPAPAEGAPAQPHEPVSARVPPTVPA MSMEG_1870|M.smegmatis_MC2_155 PVGPADPGPTRGDAPPPHTPSTPEPSHPGSSSVGEPGIRGNPEPSHTPPS TH_3868|M.thermoresistible__bu -------------VEPPAHETVLDHIENTAGNLNNLGVR-NREDTEEQPS MUL_2318|M.ulcerans_Agy99 -----APGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPGERLSPVTP Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------APAAPAPVPEEQPAPVAPPPAVVPVPIPLFPPVWEPP Mflv_3843|M.gilvum_PYR-GCK -----ITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTTPDTP MLBr_01556|M.leprae_Br4923 ------LVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANS Mb3933c|M.bovis_AF2122/97 APATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHD Rv3903c|M.tuberculosis_H37Rv APATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHD MMAR_5464|M.marinum_M SDLDPTPARPHTSRAAPASAMP----HLAGSRSTPSDVCG---------P MAV_4644|M.avium_104 ADTPAPSAPAASMSAASGPPMPPTP-SLPEPASLPSGPSGDLPAETPPTA MSMEG_1870|M.smegmatis_MC2_155 VDHTPQHAPEPATPAAQNDAPHTSAESNSTPTHQPSTSDAPASTHSPTQH TH_3868|M.thermoresistible__bu N------------------------------------------------- MUL_2318|M.ulcerans_Agy99 HVGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRPAELS Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 RRQENPWWPDRDRPRYTPPAQTQQPPIISIPGLPP--------------- Mflv_3843|M.gilvum_PYR-GCK GAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGAPANAAVD MLBr_01556|M.leprae_Br4923 GMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVD Mb3933c|M.bovis_AF2122/97 GASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQY Rv3903c|M.tuberculosis_H37Rv GASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDEAVDPQY MMAR_5464|M.marinum_M NVVS-----EGGSPGGHSTPAALDEV-------GGAPGASAPGEYHGTGG MAV_4644|M.avium_104 GIPH-----SGEPSAPSSVPPHFPDTPTHGLGDGGAHGPPESDPKNANGH MSMEG_1870|M.smegmatis_MC2_155 IGGSVGGEHSAISSDSNIGSAEHHRPVTDESRNWADEQAHRPAEQQPAHN TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 APHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGT Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 ---------IGGGDSDRGSHGGSRGGSGRGGWGDDGDSRGGSDSGSRGGW Mflv_3843|M.gilvum_PYR-GCK VATPPAPGVPGAPVVG-EAAVTTPGAPGVPGVPAGGDAGVVTPPAPGVPG MLBr_01556|M.leprae_Br4923 EHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARK Mb3933c|M.bovis_AF2122/97 GEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQE-RY Rv3903c|M.tuberculosis_H37Rv GEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQE-RY MMAR_5464|M.marinum_M GPGDHGTADGGQSLIIVDGLHADDLSALADYTGSGYLDLNNALRSDI-LD MAV_4644|M.avium_104 GPHDASLDSGSDHHLPLHPLDSDDLAALAHYTGPGYQELNFALREGA-LD MSMEG_1870|M.smegmatis_MC2_155 AAAEQPVTHDRNSAETNESREPAYSSAVNGPQPAMGPMMSPGVGSGP-GS TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 AHGTADGGDAHGDDVSGHGLSAEKRDEIIAMRKGSRPDPSEYLSPEY-IQ Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 GDNGGSRGGWGDSGSSRGGSDSGSRGGWGGNSGSHGGGSGGGSNSGF-PW Mflv_3843|M.gilvum_PYR-GCK APVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGL-AT MLBr_01556|M.leprae_Br4923 RNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQ Mb3933c|M.bovis_AF2122/97 QERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIG Rv3903c|M.tuberculosis_H37Rv QERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIG MMAR_5464|M.marinum_M ASLNARVAALNSALQKLPTYDGTVVRGTDLPPEVVAQYLPGEVITEVAFL MAV_4644|M.avium_104 VSQQARVDALQKALEKLPVYEGAVVRGTNLPADVLEQYRPGEVITEAAFT MSMEG_1870|M.smegmatis_MC2_155 PMTPHAPGPVHGGGESPSPAAKLPTPDTSTRGPETRPSHTGSPETPRAQQ TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 GHLDRFTGGATRFMPESNLDKYGIAQRDGTSFVMPKSEADAMIAGTGGDL Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 PFGGR--------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK PPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPVAPVEGAG MLBr_01556|M.leprae_Br4923 VDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASRE Mb3933c|M.bovis_AF2122/97 GDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSE Rv3903c|M.tuberculosis_H37Rv GDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSE MMAR_5464|M.marinum_M STTTDPAVAQSPTFAGNVEFRIVSRTGR----DVSSVSMFPD-----ERE MAV_4644|M.avium_104 STSTDHTVAQSSAFAGNTEFRIWSTTGR----DVSSVSMYPD-----EKE MSMEG_1870|M.smegmatis_MC2_155 PSAVGPTPGSTPSAPVHSSADQSRQSASTSPASSTSEQTAPKEHGTAPGS TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 RLMEEELGLPEGFLDSNQIVRIDIEDPRQFNLRIPSGNEAGANEQWIPGG Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGGG MLBr_01556|M.leprae_Br4923 GVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGI Mb3933c|M.bovis_AF2122/97 VAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ------------- Rv3903c|M.tuberculosis_H37Rv VAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLRQ------------- MMAR_5464|M.marinum_M ILFPAG-TKFYVIDKTLDALTG-RTIIDMIER------------------ MAV_4644|M.avium_104 ILFPAG-SKFYVVSKTVDPQTG-RTIIEMIER------------------ MSMEG_1870|M.smegmatis_MC2_155 SVPPSDSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSDLDYNPMLD TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 LLPTGASEAVVDGGKVPQGDYTVTDVFEEK-------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK AGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGGP MLBr_01556|M.leprae_Br4923 IAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFE Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 ENGHYVPGSLPSYDELLRLTRTEPDSAHYWSGRDANGVGVGPDGSGIAER TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGA MLBr_01556|M.leprae_Br4923 CGMTLGYSDIKEGDVIESYELVEKQRA----------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 IAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAAYAENARGD TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK PVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPP MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 VTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRATELFHRTT TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK APGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTVP MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 SADGPAPNGQMEPTARHDGLTSETDSRTLRDTDQDSIDRASNKPDADVRA TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGTP MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 EPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGPDGRYKISGHGDYHSGDG TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPG MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 TFTVPADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTYYPGETMPN TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK TPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGTD MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 YTLLPPDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLGSWNHRVFD TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4296c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK WSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 ----------------------------- Rv3903c|M.tuberculosis_H37Rv ----------------------------- MMAR_5464|M.marinum_M ----------------------------- MAV_4644|M.avium_104 ----------------------------- MSMEG_1870|M.smegmatis_MC2_155 VHGIYHQDTYDFIEKYPWPEPENLGDDDW TH_3868|M.thermoresistible__bu ----------------------------- MUL_2318|M.ulcerans_Agy99 ----------------------------- Mvan_1118|M.vanbaalenii_PYR-1 ----------------------------- MAB_4296c|M.abscessus_ATCC_199 ----------------------------- Mflv_3843|M.gilvum_PYR-GCK ----------------------------- MLBr_01556|M.leprae_Br4923 -----------------------------