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M. gilvum PYR-GCK Mflv_3843 (-)

annotation: hypothetical protein Mflv_3843
coordinates: 4102064 - 4105843
length: 1259

SRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTRPGEIPQALTDTARSFTEPPKP
APPVVRPPASSSSSAGTPPVPGRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPA
SGATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGGAVLPPLPPAPAG
PAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGG
GSGIGGPGGGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAGGLGG
AVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGVPVVDEAGVVTPPAPGGPGVP
TGGEGGVVTPPAPGAPGAPVVDEAGVVTPPAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAP
PAATPPSSGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPTPEITLNPANSGIDI
ATPPAPGLPGAPLEATANITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPA
NAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPGAPANAAVDVATPPAPGVPGAPVVGEAAVTTPGAPG
VPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGLA
TPPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPVAPVEGAGGAVPPAGPPPAPVFGDAGA
PVEAAAGGAPVEAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGG
APGGPVAGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGEAGVV
TPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATPPVPGVPGGGTT
VPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGT
PGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPGTPSPIAPLAATGLSNLVSP
PSLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3843--100% (1259)hypothetical protein Mflv_3843
M. gilvum PYR-GCKMflv_5091-6e-3328.26% (775) triple helix repeat-containing collagen
M. gilvum PYR-GCKMflv_4039infB1e-2735.45% (268) translation initiation factor IF-2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3543PE_PGRS578e-5431.10% (942) PE-PGRS family protein
M. tuberculosis H37RvRv3514PE_PGRS571e-4930.06% (968) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB7e-1734.48% (203) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_3131c-8e-2134.11% (258) translation initiation factor IF-2 (InfB)
M. marinum MMMAR_5294-2e-5330.30% (1152) PE-PGRS family protein
M. avium 104MAV_4827-3e-2832.73% (333) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_5700-2e-3033.41% (434) secreted protein
M. thermoresistible (build 8)TH_4426-2e-3235.41% (257) PUTATIVE AAA ATPase
M. ulcerans Agy99MUL_4367-8e-4328.33% (1013) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_2552-0.062.38% (1175) hypothetical protein Mvan_2552

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3843|M.gilvum_PYR-GCK          MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR
Mvan_2552|M.vanbaalenii_PYR-1       MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPCVGILQQVISR
Mb3543|M.bovis_AF2122/97            -------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAG
Rv3514|M.tuberculosis_H37Rv         -------MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAG
MMAR_5294|M.marinum_M               -------MSFVSVAPSLLDAAARDLAGLGAGLREANLAAAGATMGVLPAA
MUL_4367|M.ulcerans_Agy99           -------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAA
MLBr_01556|M.leprae_Br4923          -----------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTV
MAB_3131c|M.abscessus_ATCC_199      -----------MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTV
MSMEG_5700|M.smegmatis_MC2_155      -------------------MSGRHRKPTSSSSAKNVAKIAFTGAVLGGGG
TH_4426|M.thermoresistible__bu      ----------------VVRPAHPLYCAAVRAELTEPEVRGVRTELAGAAA
MAV_4827|M.avium_104                ---------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADD
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV
Mvan_2552|M.vanbaalenii_PYR-1       PGDIPQALTETARSFTNPGQPAPPVVRPPASSSSSVGTPPVPPTPPGSVV
Mb3543|M.bovis_AF2122/97            ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA
Rv3514|M.tuberculosis_H37Rv         ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA
MMAR_5294|M.marinum_M               GDEVSAAIAELFGGFGREYQAVGARMALLHDDFVRALTAGGSAYGQAEAL
MUL_4367|M.ulcerans_Agy99           GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEAL
MLBr_01556|M.leprae_Br4923          EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLD------
MAB_3131c|M.abscessus_ATCC_199      EAPVARRLRESFGGGDKPAPAASNGAAAEAAAP-----------------
MSMEG_5700|M.smegmatis_MC2_155      LGMAGQAMAATDGEWDQVARCESGGNWAINTGN-----------------
TH_4426|M.thermoresistible__bu      PTDVVGRLRWTLHALDSDAPPAAQQLTVAAEDALRLGDLGLCER------
MAV_4827|M.avium_104                AATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR-----
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP
Mvan_2552|M.vanbaalenii_PYR-1       RPSSGATPPVPPTPGTPASTTTGVGTPPVPPTPPGSTVRPAAGATPPAPP
Mb3543|M.bovis_AF2122/97            ------AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLF
Rv3514|M.tuberculosis_H37Rv         ------AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLF
MMAR_5294|M.marinum_M               NMWPLQELEQQALGVVNAPSMALFGRPLIGNGVDGVAGTGQAGGAGGILW
MUL_4367|M.ulcerans_Agy99           NMWPLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILW
MLBr_01556|M.leprae_Br4923          ------RALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELA
MAB_3131c|M.abscessus_ATCC_199      --------PKKAGPKPGAPKPAPKKVAEPVVEAPVAP-EPPAAPAAPAAP
MSMEG_5700|M.smegmatis_MC2_155      --------GYHGGLQFSPSTWRAHGGTEFAPAAYMATKEEQIAVAERVLA
TH_4426|M.thermoresistible__bu      --------FGRAAVGAAGSGAGLAARLPLAYALAFQGRGREADEVLAAVD
MAV_4827|M.avium_104                ----------DALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLL
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VPGVPAVTSTGGGTPPVPP--VPGAPVGAPVANPGLPTPPVPGAPVFGDG
Mvan_2552|M.vanbaalenii_PYR-1       VPGVPAGTPIGGGTPPLPP--VPGAPAGTPVANVAPPSPPVPGVPVIGDG
Mb3543|M.bovis_AF2122/97            GNGGAGAAGAPGQAGGPGG--PAGLWGNGGPGGAGGSG-----GGTGGAG
Rv3514|M.tuberculosis_H37Rv         GNGGAGAAGAPGQAGGPGG--PAGLWGNGGPGGAGGSG-----GGTGGAG
MMAR_5294|M.marinum_M               GNGGNGGSGAAGANGGAGG--SAGLIGTGGVGGAGGVGAVGMAGGSGGAG
MUL_4367|M.ulcerans_Agy99           GNGGNGGLGAAGANGGAGG--SAGLIGTGGVGGAGGVGAAGMTGGSGGAG
MLBr_01556|M.leprae_Br4923          PPAGQPSEQPGVPLPGQQG--TPAAPHPGHPGMPTGPHPGPAPKPGGRPP
MAB_3131c|M.abscessus_ATCC_199      APKPSPAARPAAAEAAAPA--PAPAPAP-RPGATPGPKPG-AP----RVP
MSMEG_5700|M.smegmatis_MC2_155      SQGKGAWPTCGRGLSGATPRNVVAEPEPAPLDAPGVNGELPPPAPVDMLA
TH_4426|M.thermoresistible__bu      STGLTEHELMAWALPRAANQFWMLSQPERAVAFLRTVRERVSSPTAATTL
MAV_4827|M.avium_104                VEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLES
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GAVLPPLPPAPAGPAGGPAG------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       GAALPPLPPVPGGPAAVPAG------------------------------
Mb3543|M.bovis_AF2122/97            GAGGWLFGVGGAGGVGG---------------------------------
Rv3514|M.tuberculosis_H37Rv         GAGGWLFGVGGAGGVGG---------------------------------
MMAR_5294|M.marinum_M               GSGGWLWGAGGAGGVGGAGGVGAGAGGIGGHGGAGGAGGVARSLLFGTGG
MUL_4367|M.ulcerans_Agy99           GGGGWLWGAGGSG-------------------------------------
MLBr_01556|M.leprae_Br4923          RVGNNPFSSAQSVAR-----------------------------------
MAB_3131c|M.abscessus_ATCC_199      RVGNNPFSSAQPAER-----------------------------------
MSMEG_5700|M.smegmatis_MC2_155      AP------------------------------------------------
TH_4426|M.thermoresistible__bu      DALSATFAMNAGR-------------------------------------
MAV_4827|M.avium_104                LPGGLLLVGSGVD-------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               AGGAGGVGGGGVAGVDSGTPGGAGGGGGVGGAGGAGGVGGGSRSLLFGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          -----------------------------------LVAPPAPPVPGGPAA
Mvan_2552|M.vanbaalenii_PYR-1       -----------------------------------VVTPPAPPIPGGPAA
Mb3543|M.bovis_AF2122/97            -------------------------------------AGGGTGGAGGPGG
Rv3514|M.tuberculosis_H37Rv         -------------------------------------AGGGTGGAGGPGG
MMAR_5294|M.marinum_M               GVGGEGASGGLGGGGGAGASGVGFDMAGGAGGDGGAGGAAGAGGAGGSGG
MUL_4367|M.ulcerans_Agy99           -------------------------------------GAAGAGGSGGSGG
MLBr_01556|M.leprae_Br4923          -------------------------------------PIPRPPAPRP---
MAB_3131c|M.abscessus_ATCC_199      -------------------------------------PAPRPQAPRPGAP
MSMEG_5700|M.smegmatis_MC2_155      -------------------------------------MPAPEGLPPAPEA
TH_4426|M.thermoresistible__bu      ---------------------------------------PQQALQTATEV
MAV_4827|M.avium_104                -------------------------------------VAPLKQVLQTTTF
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VPAGVALPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGS
Mvan_2552|M.vanbaalenii_PYR-1       MPAGVAAPPAP-APPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGG
Mb3543|M.bovis_AF2122/97            LIWG------GGGAGGVGGAGGG-----------TGGAGGRAELLFGAGG
Rv3514|M.tuberculosis_H37Rv         LIWG------GGGAGGVGGAGGG-----------TGGAGGRAELLFGAGG
MMAR_5294|M.marinum_M               WLWGNAGQTAGAGVGGAGGAGGAGGAGDHGVSSIAPGEAGAVGFAGGAGG
MUL_4367|M.ulcerans_Agy99           WLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAGG
MLBr_01556|M.leprae_Br4923          ---SASPSSMSPRPGGAVGGGGPR----------PPRTG-VPRPGGGRPG
MAB_3131c|M.abscessus_ATCC_199      RPGGASPSNMPPRP--SPGSMGPR----------PPRPGGGPRPGGGPRP
MSMEG_5700|M.smegmatis_MC2_155      LP-------------------------------PAPEALPPAPEAPAPAP
TH_4426|M.thermoresistible__bu      LASPTADGTAIGWAGAAAALS-------------AARMGRFTEVDALAER
MAV_4827|M.avium_104                LDVSVAEEPETALARG-----------------AALAAANAPLFASSTAA
                                                                      .               

Mflv_3843|M.gilvum_PYR-GCK          GIGGPGGGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGV
Mvan_2552|M.vanbaalenii_PYR-1       GAGAPGAPVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGL
Mb3543|M.bovis_AF2122/97            AGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGG----AGGAGGQGGA
Rv3514|M.tuberculosis_H37Rv         AG---GAGTDGGPGATGGTGGHGGVGGDGGWLAPGG----AGGAGGQGGA
MMAR_5294|M.marinum_M               AGGAGGNGVGGGVNGAGGVGGAGGAGGGGGAGASGVGAGVAGGDGGTGGA
MUL_4367|M.ulcerans_Agy99           AGGAGGNGVGGGVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTGGA
MLBr_01556|M.leprae_Br4923          APVGGRSDAGGGNYRGGGVG-ALPGGGS----GGFRGRPGGGGHGGGGRP
MAB_3131c|M.abscessus_ATCC_199      GGAGRPGGGGGGNYRGGGTGTGAPAGGPPGAGGGFRGRPGGG--GGGGRP
MSMEG_5700|M.smegmatis_MC2_155      EALPPAPEALPPAPEALPPAPEAPAPAPEALPPAPEAPAPVAEALPPAPE
TH_4426|M.thermoresistible__bu      AMSAGHPGLLRFTSGFGQTTARQLTGAPDQALALARRLTEIAQLQQPGRA
MAV_4827|M.avium_104                LAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVV
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VPPPAPPAPAPP--------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       VAPPGPPAPGVP--------------------------------------
Mb3543|M.bovis_AF2122/97            GGAGSDGGALG---------------------------------------
Rv3514|M.tuberculosis_H37Rv         GGAGSDGGALG---------------------------------------
MMAR_5294|M.marinum_M               GGAAGVGGAAGSGGVGGAAGVAGTGGDGGAGGSGGASDQGAAGVNPGEAG
MUL_4367|M.ulcerans_Agy99           GGAAGVGGAAGTGGTG----------------------------------
MLBr_01556|M.leprae_Br4923          GQRGGAAGAFGR--------------------------------------
MAB_3131c|M.abscessus_ATCC_199      GQRGGAAGAFGR--------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      ALPPAPEAPPAP--------------------------------------
TH_4426|M.thermoresistible__bu      IGELLIAEVLIT--------------------------------------
MAV_4827|M.avium_104                IEKLFLPEDSEP--------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               AVGFAGGAGGAGGAGGDSGAGGVNGSGGVGGAGGAGGGGGAGASGVGAGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          ------------------------------AGGLGGAVPPPVPGAPGVPV
Mvan_2552|M.vanbaalenii_PYR-1       ------------------------------VVDQAGVVAPPGPPAPGVPV
Mb3543|M.bovis_AF2122/97            --------------------------------GTGGTGGTGGAGGAGGRG
Rv3514|M.tuberculosis_H37Rv         --------------------------------GTGGTGGTGGAGGAGGRG
MMAR_5294|M.marinum_M               AGGDGGTGGAGGAAGVGGAAGSGGVGGAAGVAGTGGDGGDGGAGGAGSDA
MUL_4367|M.ulcerans_Agy99           --------------------------GAAGVAGTGGDGGDGGAGGAGSDA
MLBr_01556|M.leprae_Br4923          -----------------------------------PGGAPRRGRKSKRQK
MAB_3131c|M.abscessus_ATCC_199      -----------------------------------PGGAPKRGRKSKRAK
MSMEG_5700|M.smegmatis_MC2_155      ------------------------------------EALPPAPEAQIVDA
TH_4426|M.thermoresistible__bu      -----------------------------------RGDLDEAVALLRAAV
MAV_4827|M.avium_104                ------------------------------------RRRPVLLVGSGLAV
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGVPVVDEAGVVTPPAP
Mvan_2552|M.vanbaalenii_PYR-1       VDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGP
Mb3543|M.bovis_AF2122/97            ALLLGAGGQGGLGGAGGQGGMGGAGGA-GADNPTGIGGTGGDG-------
Rv3514|M.tuberculosis_H37Rv         ALLLGAGGQGGLGGAGGQGGTGGAGGD-GVLG--GVGGTGGKG-------
MMAR_5294|M.marinum_M               SVAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGGAGAAGGAGGASATVA
MUL_4367|M.ulcerans_Agy99           SLAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGGAGAAGGAGGASATVA
MLBr_01556|M.leprae_Br4923          RQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDAN-------
MAB_3131c|M.abscessus_ATCC_199      RAEYENMQAPVVGGVRLPHGNGEVIRLARGASLSDFAEKIDAN-------
MSMEG_5700|M.smegmatis_MC2_155      SLQVPADVPPAPPVEPAPPAPVDAVAAPENQNWDQAPAPADQP-------
TH_4426|M.thermoresistible__bu      KVLTPTGYSWAPLAAMLLARALGEQGAAPEAAIALSRAESRHG-------
MAV_4827|M.avium_104                VGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAP-------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GGPGVPTGGEGGVVTPPAPGAPGAPVVDEAGVVTPPAPGGPGVP------
Mvan_2552|M.vanbaalenii_PYR-1       GAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPGAPGVP------
Mb3543|M.bovis_AF2122/97            GTGGSAG--EGGAGGAAGQLFSAS---GAAGNAGVGGAGGQ---------
Rv3514|M.tuberculosis_H37Rv         GVGGVAG--LGGAGGAAGQLFSAS---GAAGNAGVGGAGGQ---------
MMAR_5294|M.marinum_M               GSGGVGG--DGGAGGAAGGGVGAAGLGGDGGHAGAGGAGGEGLSGGFNTG
MUL_4367|M.ulcerans_Agy99           GSGGVGG--DGGAGGAAGGGVGAASLGGDGGHAGAGGAGGEGLSGGFNTG
MLBr_01556|M.leprae_Br4923          ---------PAALVQALFNLGEMVTATQSVGDETLELLGSEMN-------
MAB_3131c|M.abscessus_ATCC_199      ---------PASLVQALFNLGEMVTATQSVGDETLELLGGEMN-------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------QTWALHVGGPLPLDPVLP------
TH_4426|M.thermoresistible__bu      ---------LKSMLFAPELALARAWTRAARGDRHGAVXXXXACWWWR---
MAV_4827|M.avium_104                ---------PPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAP-----
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          ---AVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAATPPSS-------
Mvan_2552|M.vanbaalenii_PYR-1       ---VDGGAELVTPPGPGAPGTPTVSSVETFSPPAPPAPGTPSS-------
Mb3543|M.bovis_AF2122/97            -----GGDGGAGGAGADADQPGATGGTGFAGGAGGAGGAGGS--------
Rv3514|M.tuberculosis_H37Rv         -----GGDGGAGGAGADADQPGATGGTGFAGGAGGAGGAGGS--------
MMAR_5294|M.marinum_M               AAGGIGGAGGAGGTGGDSGGVGGVNGDGGAGGGGGRGGDGGSSTTVAGVG
MUL_4367|M.ulcerans_Agy99           AAGGIGGAGGAGGTGGDSGGVGGVNGDGGAGGGGGRGGDGGS--------
MLBr_01556|M.leprae_Br4923          -----YNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVR---------
MAB_3131c|M.abscessus_ATCC_199      -----YVVQVVSPEDEDRELLESFDLTYGEDEGGEEDLRTR---------
MSMEG_5700|M.smegmatis_MC2_155      -------APAPAPAPAPAPGAPAAVAAPAPDPLAPAPN------------
TH_4426|M.thermoresistible__bu      ------WWDXXTPPGPPAPPAGGGGGGDVETPPGPPAPPAEVE-------
MAV_4827|M.avium_104                -----PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIP-------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GAGGAGGAGGDSGMVAGAGGTGGQAGDGGFGGFGGAGIDGGGAAGARGGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GGAGGVGGAAEATGTGGAGGSGGAAGGGGSGASAVGAGLAGGAGGDGGIG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GAAGAGGSGFVAGADGNGGFGGAGGAGGAGDQGVSGAAPGEAGAVGFAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               AGGAGGAGGNGVGGGVNGAGGVGGAGGAGGGGGAGASGVGAGVAGGDGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GGAGGAAGVGGAAGSGGVGGAAGVAGTGGDGGAGGSGGASDQGAAGVNPG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               EAGAVGFAGGAGGAGGVGGDSGAGGVNGSGGVGGAGGAGGGGGAGASGVG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               AGVAGGDGGTGGAGGAAGVGGAAGTGGVGGAAGVAGTGGDGGAGGSGGAS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               DQGAAGVNPGEAGAVGFAGGAGGAGGAGGDSGAGGVNGSGGVGGAGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGTGGVGGAAGVAGTGGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GGAGGSGGASDQGAAGVNPGEAGTVGFAGGAGGAGGVGGDSGAGGVNGSG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GVGGAGGAGGGGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGSGGVGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               AAGVAGTGGDGGDGGAGGAGSDASVAGQAGFAGGSGGAGGVGGSAGAGGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               NGSGGDGGAGGTGGIGGASATTAGVGGAGGAGGAGGTTGGGVGAAGLGGD
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5294|M.marinum_M               GGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGDSGGVGGVNGDGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          ----------GSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGS
Mvan_2552|M.vanbaalenii_PYR-1       ----------GSIETFSPPAPPTPGTPANSSVEIVTPPPPGVPGVPGEGS
Mb3543|M.bovis_AF2122/97            -----------------SGAGGTNGSGGAGG-------TGGQGGMGGAGG
Rv3514|M.tuberculosis_H37Rv         -----------------SGAGGTNGSGGAG----------GQGGAGGAGG
MMAR_5294|M.marinum_M               AGGIGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGVGAGGTGGSAGDGG
MUL_4367|M.ulcerans_Agy99           -------------STSTSGVGGAGGAGGNGGNAGFGVSAGGTGGSAGDGG
MLBr_01556|M.leprae_Br4923          -----------------PPVVTVMGHVDHG--------------------
MAB_3131c|M.abscessus_ATCC_199      -----------------PPVVTVMGHVDHG--------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          TTYTTP---------------------PTPEITLNPANSGIDIATPPAPG
Mvan_2552|M.vanbaalenii_PYR-1       TTYTTP---------------------PTPEITLNPANSSIDVATPPGPG
Mb3543|M.bovis_AF2122/97            AG---------------------------ADNPTGIGGTGGDGGTGGAAG
Rv3514|M.tuberculosis_H37Rv         AG---------------------------ADNPTGIGGTGGDGGTGGAAG
MMAR_5294|M.marinum_M               AGGFGGAGIDGSGAAGARGGDGGAGGGGGAGGVDGVGGASGNGGAAGAGG
MUL_4367|M.ulcerans_Agy99           AG-------------------------GGAGGVDGVGGASGNGGAAGAGG
MLBr_01556|M.leprae_Br4923          ----------------------------KTRLLDTIRKANVREAEAGG--
MAB_3131c|M.abscessus_ATCC_199      ----------------------------KTRLLDTIRKANVREGEAGG--
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          LPG------APLEATANITTPGTPGVPG-APVNSSIDVATPGEVGVPAAP
Mvan_2552|M.vanbaalenii_PYR-1       VPG------VPVEASANVSTPPVPGVPG-APVNSSVEVATPAEVGVPGTP
Mb3543|M.bovis_AF2122/97            AGG-------AGGAAGTGGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGAD
Rv3514|M.tuberculosis_H37Rv         AGG-------AGGAAGTGGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGAD
MMAR_5294|M.marinum_M               AGGSGIGAGIDGGAGGDGGIGGAAGFPGGGGTTGAWGTGGAGGAGGSGGA
MUL_4367|M.ulcerans_Agy99           AGGSGIGAGIDGGAGGAGGTGGAAGFPGGGGTTGAWGTGGAGGAGGAGGA
MLBr_01556|M.leprae_Br4923          ---------ITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAK
MAB_3131c|M.abscessus_ATCC_199      ---------ITQHIGAYQVAVEHDGTERPITFIDTPGHEAFTAMRARGAK
MSMEG_5700|M.smegmatis_MC2_155      ---------------ADVAPTPPEGVPHLASPENLPPGTTETPDQIPGQG
TH_4426|M.thermoresistible__bu      --------------ERDDAEIPPGPPSPPAGGGGGGEIAPPPTPGEPGAV
MAV_4827|M.avium_104                ---------VPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTV
                                                                                   .  

Mflv_3843|M.gilvum_PYR-GCK          IERSMTVTTPDTPGAPGAPANAAVDVATPPAPGVPGAPVVGEAGVTTPGA
Mvan_2552|M.vanbaalenii_PYR-1       IERSTTLTTPPTPGVPGTPVNSSVEVATPPAPGAPGVPVVDEAGVVTPPG
Mb3543|M.bovis_AF2122/97            ADQ------PGATGGTGFAGGAGGAGGAGGSSGAGGTNGSGGAGGTG---
Rv3514|M.tuberculosis_H37Rv         ADQ------PGATGGTGFAGGAGGAGGAGGSSGAGGTNGSGGAGGTG---
MMAR_5294|M.marinum_M               GDHGGVGVNPGDSGTAGWAGGAGGAGGAGGSAAVNGVNGAGGAGGNG---
MUL_4367|M.ulcerans_Agy99           GDHGGVGVNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNG---
MLBr_01556|M.leprae_Br4923          ATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADP---
MAB_3131c|M.abscessus_ATCC_199      ATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADP---
MSMEG_5700|M.smegmatis_MC2_155      PNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPG-----------
TH_4426|M.thermoresistible__bu      IDQSSQNVTVPAPPTPGSETSTALEVFSPPVP------------------
MAV_4827|M.avium_104                PQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP---
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PGAPGAPANAAVDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVP-AGGD
Mvan_2552|M.vanbaalenii_PYR-1       PGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVP-VVGE
Mb3543|M.bovis_AF2122/97            -GQGGAGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGGAAGTGGTGGM
Rv3514|M.tuberculosis_H37Rv         -GQGGAGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGGAAGTGGTGGM
MMAR_5294|M.marinum_M               -GAGGGGGAGASGIG-AGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGA
MUL_4367|M.ulcerans_Agy99           -GAGGGGGAGASGIG-AGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGA
MLBr_01556|M.leprae_Br4923          --AKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAA
MAB_3131c|M.abscessus_ATCC_199      --AKIRAQLTEYNLVAEDFGGDTMFVDISARQGTNIEQLLEAVLLTADAA
MSMEG_5700|M.smegmatis_MC2_155      ------GAAPNRPVAPPPAPGDP-------ALAPAPAPLGAPAPAPAPEP
TH_4426|M.thermoresistible__bu      -----PGEVSGGGSNMLELPGFPGGTIGGPEIAHNVEVTGPPAEASVPGV
MAV_4827|M.avium_104                --TPGAGGSGGSGGGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGGG
                                                        *                             

Mflv_3843|M.gilvum_PYR-GCK          AGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPG------------------
Mvan_2552|M.vanbaalenii_PYR-1       AGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPG------------------
Mb3543|M.bovis_AF2122/97            IGTTGNAGVGGAGGQGGDGGAG----------------------------
Rv3514|M.tuberculosis_H37Rv         IGTTGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGAGGAGKAG
MMAR_5294|M.marinum_M               AGTAGDGGAGGAGGAGDDGSAGVVSGDPGTAG------------------
MUL_4367|M.ulcerans_Agy99           AGSAGDGGAGGAGGAGDDGSAGVVSGDPGTAG------------------
MLBr_01556|M.leprae_Br4923          LDLRANSGMEAQGVAIEAHLDR----------------------------
MAB_3131c|M.abscessus_ATCC_199      LDLRANPDMEAQGVAIEAHLDR----------------------------
MSMEG_5700|M.smegmatis_MC2_155      APVGAPAPVGAPVPPPA---------------------------------
TH_4426|M.thermoresistible__bu      DASVATEAGTPPVPP-----------------------------------
MAV_4827|M.avium_104                HLPFPGAGSTPGGSGGGHLPTP----------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         GSSSAGGTNSSGSAGGTGRQSGTGGAGGAGADNPTGIGGTGGDGGTGGAA
MMAR_5294|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------VPAGGDAGVVTPPAPGVPGAPAATEAGLAT
Mvan_2552|M.vanbaalenii_PYR-1       --------------------VPVVGEAGVVTPPGPGAPGVPVVDEAGVVT
Mb3543|M.bovis_AF2122/97            ------------------------GAGGAGGSSGAGGTNG----SGGAGG
Rv3514|M.tuberculosis_H37Rv         GAGGAGGAAGTGGTGGMIGTTGNAGVGGAGGSSGAGGTNG----SGGAGG
MMAR_5294|M.marinum_M               ------------------------KAGGAGGAGGAGGNGV----AGGANG
MUL_4367|M.ulcerans_Agy99           ------------------------KAGGAGGAGGVGGNGV----AGGVNG
MLBr_01556|M.leprae_Br4923          ------------------------GRGPVATVLVQRGTLR-------IGD
MAB_3131c|M.abscessus_ATCC_199      ------------------------GRGPVATVLIQRGTLR-------VGD
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAP-----VAP
Mvan_2552|M.vanbaalenii_PYR-1       PPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPPAAAPGAP
Mb3543|M.bovis_AF2122/97            TGGQGGAGG----AGGAGADNPTGIGG--TGGDGGTGGAAGAGGAGGAAG
Rv3514|M.tuberculosis_H37Rv         TDGQGGAGG----AGGAGADNPTGIGG--TGGDGGTGGAAGAGGAGGAAG
MMAR_5294|M.marinum_M               SGGAGGAGG----AGGTGGAGASGVPASVAGGDGGAGGAGGAAGSGGAAG
MUL_4367|M.ulcerans_Agy99           SGGAGGAGG----AGGTGGAGASGVPASVDGGDGGAGGAG------GAAG
MLBr_01556|M.leprae_Br4923          SVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVD
MAB_3131c|M.abscessus_ATCC_199      SIVAGDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNLLVVD
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      -----GPTAPIEHAAETSVPAEVEIPGAEIDHRAEVATPPVDGPPVEVEN
MAV_4827|M.avium_104                --GAGTPGG------GLGGFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFG
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VEGAGGAVPPAGPPPAPVFGDAG---------------APVEAAAGGAPV
Mvan_2552|M.vanbaalenii_PYR-1       IDAAAASVAPSGPPAAPVLGEAG---------------VVAPPAP-----
Mb3543|M.bovis_AF2122/97            TGGTGGMIGTTGNAGVGG-------------------------AGGQG--
Rv3514|M.tuberculosis_H37Rv         TGGTGGMIGTTGNAGVGG-------------------------AGGQG--
MMAR_5294|M.marinum_M               TGGSGGSAGNTGAGGAGGDGGVGGAGGNAEGPGLFGYDGGMGGAGGAGGS
MUL_4367|M.ulcerans_Agy99           TGGSGGSAGNTGAGGAGG-------------------------AGGAGGS
MLBr_01556|M.leprae_Br4923          EDRIARQIADRRSARKRN--------------------------------
MAB_3131c|M.abscessus_ATCC_199      EDRIARQIADRRSARKRN--------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      SVEVATPPHXXGPGAVVDX-------------------------------
MAV_4827|M.avium_104                GGHSGGGLGGLGGGHK----------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          EAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPA
Mvan_2552|M.vanbaalenii_PYR-1       ------PGGGAPGGGAPGAGVG---TGAPIEGAAGAGGVPAAPLAANAGA
Mb3543|M.bovis_AF2122/97            -------GDGGAGGAGADADQPGATGGTGFAGGAGGAGG-----------
Rv3514|M.tuberculosis_H37Rv         -------GDGGAGGAGADADQPGATGGTGFAGGAGGAGGSGGSSCAGGTN
MMAR_5294|M.marinum_M               AGSTGVNGDGGAGGAGGVGGLGGDSAATAGGGGAGGDGGAGGAAGAGAGI
MUL_4367|M.ulcerans_Agy99           AASTGVNGDGGAGGAGGVGGLGGDSAATAGGGGAGGDG------------
MLBr_01556|M.leprae_Br4923          -----------ALAARSRKRISLEDLDSALKETSQLNLILK---------
MAB_3131c|M.abscessus_ATCC_199      -----------ALAARSRKRISLDDLDAALKETSQLNLILK---------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          AAGGAAPGGAPGGPVAGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPG
Mvan_2552|M.vanbaalenii_PYR-1       AT---PPAAATGG----------------AGAPIDAAAGAAAPPAP----
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         GSGGAGGTCGQVVAGGAGISFSNGSNGGTGGTGGVGGTGGDGGNAGTGAG
MMAR_5294|M.marinum_M               AGSAGDGGHAGAGGAGGAGLSGGFNTGAAGGIGGAGGAGGTGGDSGGVGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          GAAAVPAGAVT---------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         DPGKGGTGGTGGTGGSGGA-------------------------------
MMAR_5294|M.marinum_M               VNGDGGAGGIGGHGGDGGSSTSTPGVGGAGGAGGDGGSAGIGVGVAGNGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         ------------GGSGGANFNGGTGGTGGTGGKGGLNTDGLSSATSGTGG
MMAR_5294|M.marinum_M               DAGAGGAGGSGGAGIDGSAATGAHGGAGGSGGVGGQATNSAGVGGDGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         TGGTGGKGGTGGAGDDSAGGTGGTGGAGGNAGAGGLANTGGTAGNAGIGG
MMAR_5294|M.marinum_M               GAGGNGGAGANGTASPGVPGPGAGGDAGAGGNGGAGGGSGARNGDGGDGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------AGGSS-------------
Rv3514|M.tuberculosis_H37Rv         DGGQGGNGGQGDSGSGLGGQPGFAGGAGGKGGAGGSS-------------
MMAR_5294|M.marinum_M               VGGRGGDGHIHPGGSRINGGDGGVGGAAGLAGVNGASAAGNAGHGGDGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------PPAPGVPGAPVFGEAGVVTPPAPGVPGGAAAVPAGV
Mvan_2552|M.vanbaalenii_PYR-1       ---------------PAP---GAPIFGEAGVAAPPLPPAPGGAGAVPAGV
Mb3543|M.bovis_AF2122/97            --------------GAGGTNGSGGAGGTGGQGGAGGAGISFSNGSNGGTG
Rv3514|M.tuberculosis_H37Rv         --------------GAGGTNGSGGAGGAGGQGGAGGAGISFSNGSNGGTG
MMAR_5294|M.marinum_M               GGNGSVGAAGADGVGAGATGGFGSQGGDGGKGGAGGAGVNGVGGGDGGKG
MUL_4367|M.ulcerans_Agy99           -----------------------------GKGGAGGAGVNGVGGGDGGKG
MLBr_01556|M.leprae_Br4923          -----------------------------GDNAGTVEALEEALMGIQVDD
MAB_3131c|M.abscessus_ATCC_199      -----------------------------GDNAGTVEALEEALLGIAIDD
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      -------------------------------XXXRRPGADPRPXPLPVAA
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          VTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATPPVPGVPGGG
Mvan_2552|M.vanbaalenii_PYR-1       VTPPVPGVPGGAGAVPAGAVTPPTP----------------PVPGSSSGG
Mb3543|M.bovis_AF2122/97            GTGGVGGTGGDGGNAGTGAGDPGKGGTG----------------------
Rv3514|M.tuberculosis_H37Rv         GTGGVGGTGGDGGNAGTGAGDPGKGGTGGTGGTGGSGGAGGSGGANFNGG
MMAR_5294|M.marinum_M               GSGGTGGAGGAGG-AGSDGILPSNGGLGGLGGSGGLGGAGGAGTDGGASG
MUL_4367|M.ulcerans_Agy99           G---TGGAGGAGG-AGSDGIIPSNGGLG----------------------
MLBr_01556|M.leprae_Br4923          EVALRVIDRGVGGITETNVN------------------------------
MAB_3131c|M.abscessus_ATCC_199      EVQLRVIDRGVGGVTETNVN------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      QLHPRPVG------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          TTVPAASVTPPAPGVPGGASTVPGNAGTPSTPGL----------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         TGGTGGTGGTGGKGGMGGIAGDGGPGGDGGNAGVGGKGGTNGNGGSGGTG
MMAR_5294|M.marinum_M               ATGTYGNGGTGGAGGAGGNA------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         GTGGAGGNAGAGGLANTGGTAGNAGIGGDGGQGGNGGQGDSGSGLGGQPG
MMAR_5294|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3514|M.tuberculosis_H37Rv         FAGGPGGKGGAGGNAGTGGTNGSGAGGAGGQGGAGGAGISFSNGSNGGTG
MMAR_5294|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          ---------------------PPGSTDTYINYPAPPVPPTPPNSTGVSAG
Mvan_2552|M.vanbaalenii_PYR-1       ----------------------------FVNYPAPPVPPTPPNSAGVNTG
Mb3543|M.bovis_AF2122/97            -------------------------------GTGGSGGAGGSGGANFNGG
Rv3514|M.tuberculosis_H37Rv         GTGGVGGTGGDGGNAGTGAGDPGKGGTGGTGGTGGSGGAGGSGGANFNGG
MMAR_5294|M.marinum_M               --------------------------TGGAGEGGGLGGNGGTGGQAFGDG
MUL_4367|M.ulcerans_Agy99           ----------------------------------GNGGNGGNGGQAFGDG
MLBr_01556|M.leprae_Br4923          -----------------------------------LASASDAIIIGFNVR
MAB_3131c|M.abscessus_ATCC_199      -----------------------------------LASASDAIIIGFNVR
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      -----------------------------------CDGPRRPHRGGVVTA
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          TPGSPAPGTPGSTLTLTDLLTPPGIARTLQNTASS------VMGATPPGT
Mvan_2552|M.vanbaalenii_PYR-1       TPGSPIPGTPGSTLTISDLLTPPGVARTVQNTASS------VMSIAPPGT
Mb3543|M.bovis_AF2122/97            TGGTGGTGGTGGKGGMGGIAGDGGPGGDGGNAGVG-----GKGGTNGNGG
Rv3514|M.tuberculosis_H37Rv         TGGTGGTGGTGGKGGMGGIAGDGGPGGDGGNAGVG-----GKGGTNGNGG
MMAR_5294|M.marinum_M               VGGAGGIGGKGGNAAIGTLVVNGGVGGAGGSGGLGGATENGVGGVGGAGG
MUL_4367|M.ulcerans_Agy99           VGGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGATEDGVGGVGCAGG
MLBr_01556|M.leprae_Br4923          AEGKATELASREGVEIRYYLVIYQAIDDIEKALRG---------------
MAB_3131c|M.abscessus_ATCC_199      AEGKATELANREGVDIRYYSVIYQAIDEIESALKG---------------
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      SRQPRRLTGRVDAPHLHRHRGQPGDAQHQHGHHRR------------QRE
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PPVPGGSGSVSLAVPGTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPL
Mvan_2552|M.vanbaalenii_PYR-1       PPVPGGAGSVSVGVPAPPSPLTPLAATGLSNLVSPPSLTIPSIPGLPVPL
Mb3543|M.bovis_AF2122/97            SGGTGGTG----GPGGSGGAPTGSGTGGKGGAGGDGGDGADGGAATGVGD
Rv3514|M.tuberculosis_H37Rv         SGGTGGTG----GPGGSGGAPTGSGTGGKGGAGGDGGDGADGGAATGVGD
MMAR_5294|M.marinum_M               AGGNGGRGDTLFTAGGSGGTGGHGGGGGSASGSGTGGSGGTGGVGGIGGD
MUL_4367|M.ulcerans_Agy99           AGGNGGRGDMLFTVGGSGGTGGDGGGGGSASGSGTGGSGGTGGVGGIGGD
MLBr_01556|M.leprae_Br4923          -MLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRD
MAB_3131c|M.abscessus_ATCC_199      -MLKPVYEEVELGRAEIRAMFRSSKVGNIAGCLVTSGIIRRNAKARLLRD
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      RGFHGDRATITHTLVFNARLMMLVSALTIESPVTTAYRMAPNAAAAIVPT
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          PNTVPVPSDLLCVGTDWSASQGDSAATPPAAEVPR-VVTGAAPTGDRRDR
Mvan_2552|M.vanbaalenii_PYR-1       PNEVPVPSDLLCVGTDWSATQGDSATTPVNAEIPRALVTGAAPVGDRRDR
Mb3543|M.bovis_AF2122/97            GGDGGNGGNGGNGGTG-VGSPGGLGGAGGTGGLGGAGAGGGADGDDGDDG
Rv3514|M.tuberculosis_H37Rv         GGDGGNGGNGGNGGTG-VGSPGGLGGAGGTGGLGGAGAGGGADGDDGDDG
MMAR_5294|M.marinum_M               GKVGGSGGDGGDGGDGGSGVIGGQGGGGGIGGFGGTGAGG-APSDNGTNG
MUL_4367|M.ulcerans_Agy99           GKLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTGAGG-APSDKGING
MLBr_01556|M.leprae_Br4923          NIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELV
MAB_3131c|M.abscessus_ATCC_199      NIVVAETVTISSLRREKDDVVEVRDGYECGLTLTYNDIKEGDVIEAYELR
MSMEG_5700|M.smegmatis_MC2_155      --------------------------------------------------
TH_4426|M.thermoresistible__bu      AYSTVDIPASSTINIVVLA-------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3843|M.gilvum_PYR-GCK          WGNR---
Mvan_2552|M.vanbaalenii_PYR-1       WDTR---
Mb3543|M.bovis_AF2122/97            QPGNNGS
Rv3514|M.tuberculosis_H37Rv         QPGNNGS
MMAR_5294|M.marinum_M               EPGNPG-
MUL_4367|M.ulcerans_Agy99           EPGNPG-
MLBr_01556|M.leprae_Br4923          EKQRA--
MAB_3131c|M.abscessus_ATCC_199      EKERV--
MSMEG_5700|M.smegmatis_MC2_155      -------
TH_4426|M.thermoresistible__bu      -------
MAV_4827|M.avium_104                -------