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VKSRELSPRVRDLIREAARVALNPSQQWLEEFDRATLATAPPIAENPDLATVISRANRANLRHFAASNLR NPGDPVPANLGAEPLRMARDLVRLGLDTLALDVYRVGQNVAWQRWTDIVFGLTTDPQELRELLDVPFRSA VAFIDTTLAGIAAQMELEHHELSRNICAERRRIVELLLNGAPISRDSAESRLGYPLDRSHTAAIIWSDRP NGDHRDLDRAVDAFCNAVGCASSLAIMSAATTRWVWVRDVDVFDCSHIRQVMRELPHVRIAIGTTEPGVD GFRRSRRDALTAARMLIRLRSPQQVAFFGDVEMIALLTENPDGADEFIKNTLGDFE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1854 | - | - | 100% (336) | transcriptional activator protein |
| M. ulcerans Agy99 | MUL_3245 | - | e-114 | 57.40% (331) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_0944 | - | e-107 | 57.58% (330) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1488 | - | 1e-134 | 66.96% (336) | transcriptional activator protein |
| M. gilvum PYR-GCK | Mflv_4621 | - | 2e-09 | 25.63% (199) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1453 | - | 1e-134 | 66.96% (336) | transcriptional activator protein |
| M. leprae Br4923 | MLBr_01052 | - | 1e-105 | 54.85% (330) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 6e-46 | 33.23% (334) | hypothetical protein MAB_2657c |
| M. marinum M | MMAR_2258 | - | 0.0 | 98.21% (336) | transcriptional activator protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3143 | - | 4e-17 | 26.77% (325) | PUTATIVE putative conserved hypothetical protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1854|M.ulcerans_Agy99 ----------------MKSRELSPRVRDLIREAARVALNPSQQWLEEFDR
MMAR_2258|M.marinum_M ----------------MKSRELSPRVRDLIREAARVALNPSQQWLEEFDR
Mb1488|M.bovis_AF2122/97 ----------------MALRETSPRIHELIREAARIALNPTQEWLDEFDR
Rv1453|M.tuberculosis_H37Rv ----------------MALRETSPRIHELIREAARIALNPTQEWLDEFDR
MLBr_01052|M.leprae_Br4923 ----------------MARQHPSPRVRELIREGARIALNPTQEWIDQLDR
MAB_2657c|M.abscessus_ATCC_199 MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGEVAGDLTA
Mflv_4621|M.gilvum_PYR-GCK ---------------MLDSSEVQDTPGHAVHHLFRDLGDLVRELPESIHG
TH_3143|M.thermoresistible__bu ---------------VVVSGYNADDISSTVALIVDRLLENSGEDVERIQR
: : :
MUL_1854|M.ulcerans_Agy99 ATLATA--PPIAENPDLATVISRANRANLRHFAASNLRNPGDPVPANLGA
MMAR_2258|M.marinum_M ATLAAA--PPIAENPDLATVISRANRANLRHFAASNLRNPGDPVPANLGA
Mb1488|M.bovis_AF2122/97 AILAAN--PSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGP
Rv1453|M.tuberculosis_H37Rv AILAAN--PSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGP
MLBr_01052|M.leprae_Br4923 ATFAAN--PAIANDPVLAKVVRRASRAHLVHWATANLRDPGAPVPAHLGP
MAB_2657c|M.abscessus_ATCC_199 ASLEDPRYRTIADDPVIAEVDARLTVSNLKHWLTSNISEPGHRVRPATGS
Mflv_4621|M.gilvum_PYR-GCK LLIEQV--AELAADQQLKELLSDTVAANVDTWFSV-VRHSIPFDRMESPT
TH_3143|M.thermoresistible__bu RILADI--DELRSDPRLVELLRSSVAGNVETVLTV-IRYGIDLDRVEPPT
: : : : : .:: : : .
MUL_1854|M.ulcerans_Agy99 EPLRMARDLVRLGLDTLALD-VYRVGQNVAWQRWTDIVFGLTTDPQELRE
MMAR_2258|M.marinum_M EPLRMARDLVRLGLDTLALD-VYRVGQNVAWQRWTDIVFGLTTDPQELRE
Mb1488|M.bovis_AF2122/97 EPLRMARDLVRVGLDALALD-IYRIGQNVAWRRWTDIAFGLTSDPDELHE
Rv1453|M.tuberculosis_H37Rv EPLRMARDLVRVGLDALALD-IYRIGQNVAWRRWTDIAFGLTSDPDELHE
MLBr_01052|M.leprae_Br4923 EPLTMARDLVRRGRDVLALD-IYRVGQYTAWRRWMEIAFTLTSDPQELRE
MAB_2657c|M.abscessus_ATCC_199 AMRTYARDVVLRGLTTDDIQ-SWRAVQRVGWKWWLAACFQVTDDKEQLCE
Mflv_4621|M.gilvum_PYR-GCK AALEHARRMAQREVPVNALLRAYRLGHQYGLNLIIAGLRSADLPPEEKLA
TH_3143|M.thermoresistible__bu AALEYARRAAQHGIALSALIRAYRLGQQEMLERILREVRETELDPDLRLS
** . : :* : . :
MUL_1854|M.ulcerans_Agy99 LLDVPFRSAVAFIDTTLAGIAAQMELEHHELSRNICAERRRIVELLLNGA
MMAR_2258|M.marinum_M LLDVPFRSAAAFIDTTLAGIAAQMELEHHELSRNICAERRRIVELLLNGA
Mb1488|M.bovis_AF2122/97 LLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGA
Rv1453|M.tuberculosis_H37Rv LLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGA
MLBr_01052|M.leprae_Br4923 ILNVSAQSINEYVAATLEAIATHMQLERDELTRSTHAERLEVVDLILEGA
MAB_2657c|M.abscessus_ATCC_199 LIEVTSNSLTTFVDDSIAELAEHVRRVREELAGGSQLQRYATVELLLQGA
Mflv_4621|M.gilvum_PYR-GCK LIEHITRVSFRYIDWMSEQVLETYQTERAEWDERRRSLRAQAIRDILNGR
TH_3143|M.thermoresistible__bu VYERISSTSFAYIDWISQQVSDTYDTERERWLEHRNNIRAVRVREILDSD
: : :: : : . * : :::.
MUL_1854|M.ulcerans_Agy99 P-ISRDSAESRLGYPLDRSHTAAIIWSDR----PNGDHRDLDRAVDAFCN
MMAR_2258|M.marinum_M P-ISRDSAESRLGYPLDRSHTAAIIWSDR----SDGDHRDLDRAVDAFCN
Mb1488|M.bovis_AF2122/97 P-ISREHAEARLGYPLDRSHTAAVIWGDQ----AQGDHSHLDRVADAFGH
Rv1453|M.tuberculosis_H37Rv P-ISREHAEARLGYPLDRSHTAAVIWGDQ----AQGDHSHLDRVADAFGH
MLBr_01052|M.leprae_Br4923 P-VTQERAEARLGYRLGLTHTAAVIWSDD----LDGDHGYLDQAAEAFSH
MAB_2657c|M.abscessus_ATCC_199 D-IAPARAEAQLGYALTGSHIGAVVWVD-----SEKEIAALERASEQVMR
Mflv_4621|M.gilvum_PYR-GCK D-VDLTEASSAMRYFLGATHVALMVWLDRDAGADTDEFIAMERFMQHAVS
TH_3143|M.thermoresistible__bu EPIDIDTASAALGYPLRGRHLALVLWMTR-SDLPGGELLRLERFARAVAE
: *.: : * * * . ::* : :::
MUL_1854|M.ulcerans_Agy99 AVGCASSLAIMSAATTR---WVWVRDVDVFDCSHIRQVMRELP-HVRIAI
MMAR_2258|M.marinum_M AVGCASSLAIMSAATTR---WVWVRDVDVFDCSRIRQVMRELP-HVRIAI
Mb1488|M.bovis_AF2122/97 AGGCPHPLVVVAGAATR---WVWVKDAPGFDIDLIHEVLHDIP-DARIAI
Rv1453|M.tuberculosis_H37Rv AGGCPHPLVVVAGAATR---WVWVKDAPGFDIDLIHEVLHDIP-DARIAI
MLBr_01052|M.leprae_Br4923 VVESTQQLIVVASAATR---WVWLADALALDVPEVQKALLNLS-KARVAI
MAB_2657c|M.abscessus_ATCC_199 ACGADRRLTVVAGTVAL---WLWIPAKTTPTVAVLMDSLGRRS-GVRVAL
Mflv_4621|M.gilvum_PYR-GCK ATGAKQS-VYFSIDRLVGCAWMTV-HRPSDYLSQLRDFVRAQPDGPRLSV
TH_3143|M.thermoresistible__bu AFQLRNTPLFVAEDTVSGWAWLAINHVVTEPVRTIRELAETADNGVHVAL
. .: *: : : . ::::
MUL_1854|M.ulcerans_Agy99 GTTEPGVDGFRRSRRDALTAARMLIRLR--SPQQVAFFGD--VEMIALLT
MMAR_2258|M.marinum_M GTTEPGVDGFRRSHRDALTAARMLIRLR--SPQQVAFFGD--VEMIALLT
Mb1488|M.bovis_AF2122/97 GATAPGIEGFRRSHRDALTTARMIIRLE--SPHRVAFFTD--VEMVALLT
Rv1453|M.tuberculosis_H37Rv GATAPGIEGFRRSHRDALTTARMIIRLE--SPHRVAFFTD--VEMVALLT
MLBr_01052|M.leprae_Br4923 GTSSAGIEGFRRSHLEALTAQRTLARLK--SHQQVAFFAD--VQLVSLIT
MAB_2657c|M.abscessus_ATCC_199 GRAATGMAGFRRTHMDAAAAQRLLARLG--SPLSVVRYED--VHLMDLLS
Mflv_4621|M.gilvum_PYR-GCK GEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVALASMLM
TH_3143|M.thermoresistible__bu GTVDDGLEGFRRSHRRARDARKVAAAS--AIPPRITAADDYGISVSALLT
* *: ****: * : :. * : : ::
MUL_1854|M.ulcerans_Agy99 ENPDGADEFIKNTLGDFE--------------------------------
MMAR_2258|M.marinum_M ENPDGADEFIKNTLGDFEEASP---ALQHTLLTFISQQCNASRAARLLYT
Mb1488|M.bovis_AF2122/97 ENAEGADDFIQRTLGNLESASP---ALKTTLLTFINQQCNASRAARLLFT
Rv1453|M.tuberculosis_H37Rv ENAEGADDFIQRTLGNLESASP---ALKTTLLTFINQQCNASRAARLLFT
MLBr_01052|M.leprae_Br4923 QNPEDAKEFITSTLGDFESASP---ALQQTLLTFINEQCNASRAAKRLFT
MAB_2657c|M.abscessus_ATCC_199 ADPASADQFVTDVLGEFQSASP---VLHQTVLTYVEEALNRTSTAERLYT
Mflv_4621|M.gilvum_PYR-GCK TDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVFLRAGSSFKAAANELQI
TH_3143|M.thermoresistible__bu ENLADTRRWVLDTLGPLASDTANDARLRETLLVFLHVGSSYTAAAERLLL
: :: .** :
MUL_1854|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2258|M.marinum_M HRNTLMHRLETAQRLLPKPLEDTTVRVAVALEVLQWRSKQPGNPAASGAG
Mb1488|M.bovis_AF2122/97 HRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKES
Rv1453|M.tuberculosis_H37Rv HRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKPTSDPPAKKES
MLBr_01052|M.leprae_Br4923 HRNTLLRRIESAEKLLPRPLDHTSVHIAVALEALQWRGDQTNTSGPRAGR
MAB_2657c|M.abscessus_ATCC_199 HRNTIDRRLARVDELLPKPFARNPIEVAAALTLLRVRAGR----------
Mflv_4621|M.gilvum_PYR-GCK HANTVKYRVNRALERRGRPIAAERLDVEVALLMCYWLGEVALNPTQALGR
TH_3143|M.thermoresistible__bu HPNSVRYRVNRAVERRARPIGEDRLEVELALLACRHFQQAVLQPAD----
MUL_1854|M.ulcerans_Agy99 ------------
MMAR_2258|M.marinum_M KPDDRTPPEQRP
Mb1488|M.bovis_AF2122/97 NGTKMR------
Rv1453|M.tuberculosis_H37Rv NGTKMR------
MLBr_01052|M.leprae_Br4923 NDGVPA------
MAB_2657c|M.abscessus_ATCC_199 ------------
Mflv_4621|M.gilvum_PYR-GCK S-----------
TH_3143|M.thermoresistible__bu ------------