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M. ulcerans Agy99 MUL_0570 (-)

annotation: PE_PGRS family protein
coordinates: 575111 - 576157
length: 348

SFVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSAAVAAMFDAQGQAYQLLSARAAA
FHEQFLQALSGGGASYAAGEAAAVSPLLDAINAPVLADTGRPLIGNGANGGAAGWLIGNGGAGGSGTPGT
ASVAGGNGGNGGAGGLLFGTGGAGGAGGTASSLVGAIPGGNGGYGGDGGLLFGRGGAGGAGGFGNNTTGG
IGGLGGAGGLFGAGGDGGVGGFGTFAGNGGDGGTGLFAAGGDSGAGGDSVGGADGGDGGNGGKAGLVGQG
GDGGAGGNNNSGFGTGGSGGKGGDAVLIGNGGNGGNAGSGGVGPGIAGAAGIGGLLIGEDGMAGLTP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0570--100% (348)PE_PGRS family protein
M. ulcerans Agy99MUL_3056-4e-9552.01% (398) PE-PGRS family protein
M. ulcerans Agy99MUL_4524-4e-9450.12% (423) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0286cPE_PGRS31e-10656.74% (393) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-5351.07% (233) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1759cwag221e-11057.80% (391) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1137.36% (91) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-1e-2938.15% (270) hypothetical protein MAB_4284c
M. marinum MMMAR_0608-1e-16082.87% (356) PE-PGRS family protein
M. avium 104MAV_1346-3e-2235.85% (265) PE family protein
M. smegmatis MC2 155MSMEG_0868-7e-4537.68% (345) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_4332-8e-3733.24% (373) PUTATIVE -
M. vanbaalenii PYR-1Mvan_1264-1e-5352.30% (239) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               --------------------------------------------------
Mb0286c|M.bovis_AF2122/97           --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               --------------------------------------------------
Mb0286c|M.bovis_AF2122/97           --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               --------------------------------------------------
Mb0286c|M.bovis_AF2122/97           --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               --------------------------------------------------
Mb0286c|M.bovis_AF2122/97           --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           ------------------------------------MSFVITAPEALTAA
MMAR_0608|M.marinum_M               ------------------------------------MSFVITAPEALTAA
Mb0286c|M.bovis_AF2122/97           ------------------------------------MSFVIAAPEVIAAA
Rv1759c|M.tuberculosis_H37Rv        ------------------------------------MSFVIAVPETIAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          -----------------------------------MPLFLNAEPQALTAA
MAV_1346|M.avium_104                -----------------------------------MS-FVTTRPEALLAV
                                                                                      

MUL_0570|M.ulcerans_Agy99           ATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSAAVAAMFDAQGQAYQL
MMAR_0608|M.marinum_M               ATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSAAVAALFDAQGQAYQL
Mb0286c|M.bovis_AF2122/97           ATDLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQA
Rv1759c|M.tuberculosis_H37Rv        ATDLADLGSTIAGANAAAAANTTSLLAAGADEISAAIAALFGAHGRAYQA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_4332|M.thermoresistible__bu      ---------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPR------
MAB_4284c|M.abscessus_ATCC_199      ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV
MLBr_01183|M.leprae_Br4923          ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MAV_1346|M.avium_104                ASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSALQAAQFSAYGTWYQQ
                                                                .    .   .            

MUL_0570|M.ulcerans_Agy99           LSARAAAFHEQFLQALSGGGASYAAGEAAAVSPLLDAINAPVLADTGRPL
MMAR_0608|M.marinum_M               LSARAATFHEQFLQALSGGGASYAAAEAAAVSPLLDAINAPVLAATGRPL
Mb0286c|M.bovis_AF2122/97           LSAQAQAFHAQFVQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPL
Rv1759c|M.tuberculosis_H37Rv        ASAEAAAFHGRFVQALTTGGGAYAAAEAAAVTPLLNSINAPVLAATGRPL
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG----------APGV
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG----------APGV
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG--------TGGT
TH_4332|M.thermoresistible__bu      ----------------------------------------------TVEY
MAB_4284c|M.abscessus_ATCC_199      VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPD--------GPSI
MLBr_01183|M.leprae_Br4923          HASQGATNHQDLIQSLLTSSSAYAGTETAN--------------------
MAV_1346|M.avium_104                VSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTSAAALQGLAPNVIPNA
                                                                                      

MUL_0570|M.ulcerans_Agy99           IGNGAN--------GGAAGWLIGNGGAGGSGTPGTASVAGGNG-------
MMAR_0608|M.marinum_M               IGNGANGAPGTGADGGAAGWLIGNGGAGGSGTPGTASVAGGNG-------
Mb0286c|M.bovis_AF2122/97           IGNGANGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAG----
Rv1759c|M.tuberculosis_H37Rv        IGNGANGAPGTGANGGDAGWLIGNGGAGGSGAKGANGGAGGPGGAA----
Mflv_5091|M.gilvum_PYR-GCK          AGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------
Mvan_1264|M.vanbaalenii_PYR-1       AGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------
MSMEG_0868|M.smegmatis_MC2_155      GGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYV
TH_4332|M.thermoresistible__bu      EYSLVACDSTLPLMCEAGDSVGGLGGASHDRSAFSASALGMAS-------
MAB_4284c|M.abscessus_ATCC_199      LSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN------
MLBr_01183|M.leprae_Br4923          ----------HDSL------------------------------------
MAV_1346|M.avium_104                APAADPPPAGTTSLGTSIGWAQNVGAAASDFITLGEGQFAPVPGAAG---
                                                                                      

MUL_0570|M.ulcerans_Agy99           ------------GNGGAGG-------------------------------
MMAR_0608|M.marinum_M               ------------GNGGAGG-------------------------------
Mb0286c|M.bovis_AF2122/97           ---------GLIGNGGAGGAGGVASS------------------------
Rv1759c|M.tuberculosis_H37Rv        ---------GLFGNGGAGGAGGTATANN----------------------
Mflv_5091|M.gilvum_PYR-GCK          -------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------
Mvan_1264|M.vanbaalenii_PYR-1       -------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------
MSMEG_0868|M.smegmatis_MC2_155      LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA
TH_4332|M.thermoresistible__bu      --------FGPDWNPGGAFLG-----------------------------
MAB_4284c|M.abscessus_ATCC_199      --------RGPLLDLSFGDLQ-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ---------IPNFNPGLTAATTAGPP------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------LLFGTGGAGGAGGTASSLVGAIP-------
MMAR_0608|M.marinum_M               --------------------LLFGTGGAGGAGGTASSLVGAIP-------
Mb0286c|M.bovis_AF2122/97           --------GIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAG--GFTNG
Rv1759c|M.tuberculosis_H37Rv        --------GIGGAGGAGGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK          --------AVGAAGAAG------TVGTAGATGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1       --------AIGTAGVAG------AAGTAGATGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155      NGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGS------
TH_4332|M.thermoresistible__bu      -----------------------LIGPGGLLIGDG---------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------FGNRDTTAIGDG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----------------------APAAPAAAAGAP---------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           ----------------------GGNGGYGGDG------------------
MMAR_0608|M.marinum_M               ----------------------GGNGGYGGDG------------------
Mb0286c|M.bovis_AF2122/97           -------------------SALGGAGGAGGAGGLFATGGVGGSGGAGSSG
Rv1759c|M.tuberculosis_H37Rv        NAGMLAGAAGAGGAGGFSFSTAGGAGGAGGAGGLFTTGGVGGAGGQGHTG
Mflv_5091|M.gilvum_PYR-GCK          ---------------------TGANGGAGGVGGVGGTGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------VGGNGGAGQAGGIGGTGAAG---------
MSMEG_0868|M.smegmatis_MC2_155      ---------------TAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNG
TH_4332|M.thermoresistible__bu      ---------------------LNGTDAYIDENGVFHEATRG---------
MAB_4284c|M.abscessus_ATCC_199      ------------------AVAVGGSNSGPIASGQGSTAVNG---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------VLASMGRGPSIGGLSVPPSWAP--------
                                                                                      

MUL_0570|M.ulcerans_Agy99           ----------GLLFGRGGAGGAGGFGNN---TTGGIGGLGGAGGLFGAGG
MMAR_0608|M.marinum_M               ----------GLLFGRGGAGGAGGFGNN---TTGGIGGLGGAGGLFGAGG
Mb0286c|M.bovis_AF2122/97           GAG--GAGGAGGLFGAGGTGGHGGFADS---SFGGVGGAGGAGGLFGAGG
Rv1759c|M.tuberculosis_H37Rv        GAG--GAGGAGGLFGAGGMGGAGGFGDHGTLGTGGAGGDGGGGGLFGAGG
Mflv_5091|M.gilvum_PYR-GCK          -----AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGA
Mvan_1264|M.vanbaalenii_PYR-1       -----AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGG
MSMEG_0868|M.smegmatis_MC2_155      AVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATG
TH_4332|M.thermoresistible__bu      -------------GNGGLLWGNGGKGGN--GLDAGLYTVPDPDNPGSTIQ
MAB_4284c|M.abscessus_ATCC_199      -------DVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ----------GGVAPAANATPAQLVGAGFTSAAPDTAPVTAVPGGVPSMA
                                                                                      

MUL_0570|M.ulcerans_Agy99           DGGVGG--------------------------FGTFAGNGGDGGTG----
MMAR_0608|M.marinum_M               DGGVGG--------------------------FGTFAGNGGDGGTG----
Mb0286c|M.bovis_AF2122/97           EGGSGGHSLVAGGDGGAGGNAG-------MLALGAAGGAGGIGGDGGTLT
Rv1759c|M.tuberculosis_H37Rv        DGGAGGSGLTTGGAAGNGGNAG-------TLSLGAAGGAGGTGGAGGTVF
Mflv_5091|M.gilvum_PYR-GCK          VGGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDAD
Mvan_1264|M.vanbaalenii_PYR-1       AGGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDAT
MSMEG_0868|M.smegmatis_MC2_155      ADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDAL
TH_4332|M.thermoresistible__bu      MYFEASDG-----------------------------ADGGRGG------
MAB_4284c|M.abscessus_ATCC_199      VTVVDDHSQRNTTNINDS-------------FNTDRSTNIGSGNTTNTEI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                TAGRGGYG--------------------------LGAPRYGVKPTVMPKP
                                                                                      

MUL_0570|M.ulcerans_Agy99           ----------------------------------------LFA-------
MMAR_0608|M.marinum_M               ----------------------------------------LFA-------
Mb0286c|M.bovis_AF2122/97           AGGI------------------------GGAGGAGGNAGLLFG-------
Rv1759c|M.tuberculosis_H37Rv        GGGK------------------------GGAGGAGGNAGMLFG-------
Mflv_5091|M.gilvum_PYR-GCK          SMGS------------------AGATGGKGGNGGNGGRGGLFG-------
Mvan_1264|M.vanbaalenii_PYR-1       SMGE------------------AGATGGKGGNGGNGGRGSLFG-------
MSMEG_0868|M.smegmatis_MC2_155      VMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSA
TH_4332|M.thermoresistible__bu      ---------------------------------------FLFG-------
MAB_4284c|M.abscessus_ATCC_199      GSHN------------------------------QANIGTSTS-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                AI------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------AGGDSGAGG---------------------------------
MMAR_0608|M.marinum_M               --------AGGDGGAGGSGL------------------TQGGDGGIGGAA
Mb0286c|M.bovis_AF2122/97           --------SGGSGGAGGFGF------------------ADGGQGGPGGNA
Rv1759c|M.tuberculosis_H37Rv        --------SGGGGGTGGFGF------------------AAGGQGGVGGSA
Mflv_5091|M.gilvum_PYR-GCK          --------KGGNAGNGAD----------------------GGTGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1       --------RGGNAGNGGN----------------------GGTGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155      TSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFN
TH_4332|M.thermoresistible__bu      --------NGGDGGNGGN---------------------------VGGKN
MAB_4284c|M.abscessus_ATCC_199      --------AGGSAAVGGN----------------------AGLAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               LGLFGAGGAGGTGGEGG---------------------------------
Mb0286c|M.bovis_AF2122/97           GTVFGSGGAGGNGGVG------------------QGFAGGIGGAGGTPGL
Rv1759c|M.tuberculosis_H37Rv        GMLSGSGGSGGAGGSGGP---------------AGTAAGGAGGAGGAPGL
Mflv_5091|M.gilvum_PYR-GCK          GTGG-TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GTGG-TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGA
TH_4332|M.thermoresistible__bu      GADPVTATVAADKS----------------------------------VA
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGN---------------------------AGLAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               --------------------------------------------------
Mb0286c|M.bovis_AF2122/97           IGNGGNGGNGGASAVTGGNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGV
Rv1759c|M.tuberculosis_H37Rv        IGNGGNGGNGGESGGTGGVGGAGGNAVLIGNGGEGGIGAL-AGKSGFGGF
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG---------
MSMEG_0868|M.smegmatis_MC2_155      NGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGV-------
TH_4332|M.thermoresistible__bu      GGNGGNGGRGGLLFGLGGNGGNGGWSTTSYLDARGGNGGNG---------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               ------------------------------------------------LF
Mb0286c|M.bovis_AF2122/97           SGLLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQTLTGRPLIGNGANGT
Rv1759c|M.tuberculosis_H37Rv        GGLLLGADGYNAPESTSPWHNLQQDILSFINEPTEALTGRPLIGNGDSGT
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------------------GD
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------------------GT
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------------------GLGN
TH_4332|M.thermoresistible__bu      ------------------------------------------------GL
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------------LAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               GGAGGMGGSAGMLF--------GNGGDGGAGAAA---------TIGNAAG
Mb0286c|M.bovis_AF2122/97           PGTGADGGAGGWLF--------GNGGNGGSGATG---------TNGGDGG
Rv1759c|M.tuberculosis_H37Rv        PGTGDDGGAGGWLF--------GNGGNGGAGAAG---------TNGSAGG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGLGG
MSMEG_0868|M.smegmatis_MC2_155      GGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGG
TH_4332|M.thermoresistible__bu      GGVLRPGGLLSLLLP--------SGAASEPGGLF-------------TGG
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAG--------LAGNAGLAGNAG-------------LAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               NGGAGGNAGMLIGAGGAGGNGGF---------------------------
Mb0286c|M.bovis_AF2122/97           DGGAGGIFFGTGGTGGAGGVGTTG------------TGGDGGAGGAAFLV
Rv1759c|M.tuberculosis_H37Rv        AGGAGGILFGTGGAGGAGGVGTAG------------AGGAGGAGGSAFLI
Mflv_5091|M.gilvum_PYR-GCK          TGGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-L
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-L
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTL
TH_4332|M.thermoresistible__bu      NGGNGGLAIANHWVG-----------------------ITDGVPGPDDDA
MAB_4284c|M.abscessus_ATCC_199      NAGLAG----NAGLAGNAGLAG-----------------NAAVAGNAAVA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0608|M.marinum_M               -------------------------GFSASDGGAGGAGGNAGFLYGAGGA
Mb0286c|M.bovis_AF2122/97           GSGGNGG----------------SGGAGLTAGGDGGDGGNAGSFFGAAGT
Rv1759c|M.tuberculosis_H37Rv        GSGGTGG----------------VGGAATTTGGVGGAGGNAGLLIGAAGL
Mflv_5091|M.gilvum_PYR-GCK          GGGGGTG-----------------------GQGGTGGTGGQGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGTG-----------------------GTGGTGGTGGQGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTI
TH_4332|M.thermoresistible__bu      VSSSAYG-----------------------GHGGHGAGPGSGGNGGSAVA
MAB_4284c|M.abscessus_ATCC_199      GNAAVAG---------------------NAAVGGVLNTGVSGAIGGSSHV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           -----------------DSVGG-----ADGGDGGNGGK------------
MMAR_0608|M.marinum_M               GGAGG------------DSVGG-----ADGGDGGNGGK------------
Mb0286c|M.bovis_AF2122/97           GGAG-----ASTKAGGTGGTGGNGGLFANGGAGGSGGLGGDAG-TGGAGG
Rv1759c|M.tuberculosis_H37Rv        GGCGGGAFTAGVTTGGAGGTGGAAGLFANGGAGGAGGTGSTAGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          GGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG
MSMEG_0868|M.smegmatis_MC2_155      EANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGT
TH_4332|M.thermoresistible__bu      NSLG-------NAIAGNGGDAGRFVLIGPGGNGGNGGTGLXXXPRPRR--
MAB_4284c|M.abscessus_ATCC_199      GGAIN------ESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           -----------------------------------------AGLVGQGGD
MMAR_0608|M.marinum_M               -----------------------------------------AGLVGQGGD
Mb0286c|M.bovis_AF2122/97           NGGLFGAGGTGGAGG-------------SLGPG-AGGAGGNGGLFGAGGT
Rv1759c|M.tuberculosis_H37Rv        AGGLYAHGGTGGPGGN----------GGSTGAGGTGGAGGPGGLYGAGGS
Mflv_5091|M.gilvum_PYR-GCK          AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN
TH_4332|M.thermoresistible__bu      ------------------------------RRNHRRTRRRPNGRRPRPPP
MAB_4284c|M.abscessus_ATCC_199      --------------------------GISESLGGSGSVGGSTAVGGGAHT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           GGAGGNN-------------------------------------------
MMAR_0608|M.marinum_M               GGAGGNN-------------------------------------------
Mb0286c|M.bovis_AF2122/97           GGSGGHGTPAAVPGGAGGAGGNAGLFSLGASGGAGGSGGSSLTDS-----
Rv1759c|M.tuberculosis_H37Rv        GGAGGHG---GMAGGGGGVGGNAGSLTLNASGGAGGSGGSSLSGK-----
Mflv_5091|M.gilvum_PYR-GCK          GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155      GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA
TH_4332|M.thermoresistible__bu      GR------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GVGGGVS------TGVGVGSHVGGGISESLGGSGSVGGSTAVGG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           -------------------------------------------------N
MMAR_0608|M.marinum_M               -------------------------------------------------N
Mb0286c|M.bovis_AF2122/97           ----GGIGGVGGAGGLLFGYGGAGGAGGYSNIGAGGAGGAGGN---AGML
Rv1759c|M.tuberculosis_H37Rv        ----AGAGGAGGSAGLFYGSGGAGGNGGYSLNGTGGDGGTGGAGQITGLR
Mflv_5091|M.gilvum_PYR-GCK          -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
Mvan_1264|M.vanbaalenii_PYR-1       -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
MSMEG_0868|M.smegmatis_MC2_155      AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSA
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------GAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVG-------G
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           SGFG------------TGGSGGKGG-----------DAVLIGNGG-----
MMAR_0608|M.marinum_M               SGFG------------TGGSGGKGG-----------DAVLIGNGG-----
Mb0286c|M.bovis_AF2122/97           SGSGGSGGTGGASGAAKGGVGGNGG-----------TAGVFGNGGDGGAG
Rv1759c|M.tuberculosis_H37Rv        SGFGGAGGAGGASDTGAGGNGGAGG-----------KAGLYGNGGDGGAG
Mflv_5091|M.gilvum_PYR-GCK          AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKG
Mvan_1264|M.vanbaalenii_PYR-1       AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      VAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STAVGGGAHTSAINDALGGSGSVGG----------STAVGGGAHTSAINE
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           --------------------NGGNAGSGGVGPGIAGAAGIGGLLIGEDGM
MMAR_0608|M.marinum_M               --------------------NGGNAGSGGVGPGIAGAAGIGGLLIGEDGM
Mb0286c|M.bovis_AF2122/97           GFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGL
Rv1759c|M.tuberculosis_H37Rv        GDGA-TSGKGGAGGNAVVIGNGGNGGNAGKAGGTAGAGGAGGLVLGRDGQ
Mflv_5091|M.gilvum_PYR-GCK          GAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1       GDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155      GDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGT
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

MUL_0570|M.ulcerans_Agy99           AGLTP----
MMAR_0608|M.marinum_M               AGLTP----
Mb0286c|M.bovis_AF2122/97           NGLP-----
Rv1759c|M.tuberculosis_H37Rv        HGLT-----
Mflv_5091|M.gilvum_PYR-GCK          GGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       GGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      AGTTGANNP
TH_4332|M.thermoresistible__bu      ---------
MAB_4284c|M.abscessus_ATCC_199      PGAEHH---
MLBr_01183|M.leprae_Br4923          ---------
MAV_1346|M.avium_104                ---------