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SFVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSAAVAALFDAQGQAYQLLSARAAT FHEQFLQALSGGGASYAAAEAAAVSPLLDAINAPVLAATGRPLIGNGANGAPGTGADGGAAGWLIGNGGA GGSGTPGTASVAGGNGGNGGAGGLLFGTGGAGGAGGTASSLVGAIPGGNGGYGGDGGLLFGRGGAGGAGG FGNNTTGGIGGLGGAGGLFGAGGDGGVGGFGTFAGNGGDGGTGLFAAGGDGGAGGSGLTQGGDGGIGGAA LGLFGAGGAGGTGGEGGLFGGAGGMGGSAGMLFGNGGDGGAGAAATIGNAAGNGGAGGNAGMLIGAGGAG GNGGFGFSASDGGAGGAGGNAGFLYGAGGAGGAGGDSVGGADGGDGGNGGKAGLVGQGGDGGAGGNNNSG FGTGGSGGKGGDAVLIGNGGNGGNAGSGGVGPGIAGAAGIGGLLIGEDGMAGLTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0608 | - | - | 100% (476) | PE-PGRS family protein |
| M. marinum M | MMAR_4398 | - | e-146 | 59.15% (497) | PE-PGRS family protein, PE_PGRS9_3 |
| M. marinum M | MMAR_1391 | - | e-141 | 60.29% (491) | PE-PGRS family protein, PE_PGRS9 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | 1e-158 | 63.80% (489) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 9e-79 | 43.45% (435) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1759c | wag22 | 1e-161 | 61.89% (509) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 38.46% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-39 | 34.92% (358) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_1346 | - | 2e-22 | 35.32% (269) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-63 | 40.72% (447) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-38 | 39.39% (297) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0570 | - | 1e-160 | 82.87% (356) | PE_PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 8e-81 | 43.10% (471) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 --------------------------------------------------
Rv1759c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M ------------------------------------MSFVITAPEALTAA
MUL_0570|M.ulcerans_Agy99 ------------------------------------MSFVITAPEALTAA
Mb0286c|M.bovis_AF2122/97 ------------------------------------MSFVIAAPEVIAAA
Rv1759c|M.tuberculosis_H37Rv ------------------------------------MSFVIAVPETIAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFLNAEPQALTAA
MAV_1346|M.avium_104 -----------------------------------MS-FVTTRPEALLAV
MMAR_0608|M.marinum_M ATDLASLG--------------------------------STIGAANAAA
MUL_0570|M.ulcerans_Agy99 ATDLASLG--------------------------------STIGAANAAA
Mb0286c|M.bovis_AF2122/97 ATDLASLG--------------------------------SSISAANAAA
Rv1759c|M.tuberculosis_H37Rv ATDLADLG--------------------------------STIAGANAAA
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 ANTLEGLS--------------------------------AATVASNAAA
MAV_1346|M.avium_104 ASMLEGLG--------------------------------SSMDAQNAAA
MMAR_0608|M.marinum_M VAP---------------------------------------TTAVLAAG
MUL_0570|M.ulcerans_Agy99 VAP---------------------------------------TTAVLAAG
Mb0286c|M.bovis_AF2122/97 AAN---------------------------------------TTALMAAG
Rv1759c|M.tuberculosis_H37Rv AAN---------------------------------------TTSLLAAG
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923 AQL---------------------------------------TTEIAPPA
MAV_1346|M.avium_104 AAP---------------------------------------TTSIAPAA
MMAR_0608|M.marinum_M ADEVSAAVAALFDAQGQAYQLLSARAATFHEQFLQALSGGGASYAAAEAA
MUL_0570|M.ulcerans_Agy99 ADEVSAAVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAA
Mb0286c|M.bovis_AF2122/97 ADEVSTAIAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAA
Rv1759c|M.tuberculosis_H37Rv ADEISAAIAALFGAHGRAYQAASAEAAAFHGRFVQALTTGGGAYAAAEAA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETA
MAV_1346|M.avium_104 ADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAA
MMAR_0608|M.marinum_M AVSPLLDAINAPVLAATGRPLIGNGANGAPGTGADGGAAGWLIGNGGAGG
MUL_0570|M.ulcerans_Agy99 AVSPLLDAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAGG
Mb0286c|M.bovis_AF2122/97 AVSPLLDPINEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGGAGG
Rv1759c|M.tuberculosis_H37Rv AVTPLLNSINAPVLAATGRPLIGNGANGAPGTGANGGDAGWLIGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923 N------------------------------HDSL---------------
MAV_1346|M.avium_104 NRVNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLGTSIGWAQNVGAAAS
MMAR_0608|M.marinum_M SGTPGTASVAGGNG------GNGGAGG-----------------------
MUL_0570|M.ulcerans_Agy99 SGTPGTASVAGGNG------GNGGAGG-----------------------
Mb0286c|M.bovis_AF2122/97 SGAAGVNGGAGGNGGAGGLIGNGGAGGAGGVASS--------GIGGSGGA
Rv1759c|M.tuberculosis_H37Rv SGAKGANGGAGGPGGAAGLFGNGGAGGAGGTATANN------GIGGAGGA
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 DFITLGEGQFAPVPGAAGIPNFNPGLTAATTAGPP---------------
MMAR_0608|M.marinum_M ----LLFGTGGAGGAGGTASSLVGAIP-----------------------
MUL_0570|M.ulcerans_Agy99 ----LLFGTGGAGGAGGTASSLVGAIP-----------------------
Mb0286c|M.bovis_AF2122/97 GGNAMLFGAGGAGGAGGGVVALTGGAG--GFTNG----------------
Rv1759c|M.tuberculosis_H37Rv GGSAMLFGAGGAGGAGGAATSLVGGIGGTGGTGGN---------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------APAAPAAAAG---------------------------------
MMAR_0608|M.marinum_M ----------------------------------------GGNGGYGGDG
MUL_0570|M.ulcerans_Agy99 ----------------------------------------GGNGGYGGDG
Mb0286c|M.bovis_AF2122/97 -------------------------------------SALGGAGGAGGAG
Rv1759c|M.tuberculosis_H37Rv -------------------AGMLAGAAGAGGAGGFSFSTAGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------ADHGSNVGVD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------APVLASMG
MMAR_0608|M.marinum_M -------------------------------GLLFGRGGAGGAGGFGNN-
MUL_0570|M.ulcerans_Agy99 -------------------------------GLLFGRGGAGGAGGFGNN-
Mb0286c|M.bovis_AF2122/97 GLFATGGVGGSGGAGSSGGAG-----GAGGAGGLFGAGGTGGHGGFADS-
Rv1759c|M.tuberculosis_H37Rv GLFTTGGVGGAGGQGHTGGAG-----GAGGAGGLFGAGGMGGAGGFGDHG
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 RGPSIGGLSVPP---------------SWAPGGVAPAANATPAQLVGAGF
MMAR_0608|M.marinum_M --TTGGIGGLGGAGGLFGAGGDGGVGG-----------------------
MUL_0570|M.ulcerans_Agy99 --TTGGIGGLGGAGGLFGAGGDGGVGG-----------------------
Mb0286c|M.bovis_AF2122/97 --SFGGVGGAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGGNAG-------
Rv1759c|M.tuberculosis_H37Rv TLGTGGAGGDGGGGGLFGAGGDGGAGGSGLTTGGAAGNGGNAG-------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ---------VDVVGGNP---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTNTEIGSHN--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 TSAAPDTAPVTAVPGGVPSMATAGRGGYG---------------------
MMAR_0608|M.marinum_M ---FGTFAGNGGDGGTG--------------------------LFAAGGD
MUL_0570|M.ulcerans_Agy99 ---FGTFAGNGGDGGTG--------------------------LFAAGGD
Mb0286c|M.bovis_AF2122/97 MLALGAAGGAGGIGGDGGTLTAGGIGGAGGA------GGNAGLLFGSGGS
Rv1759c|M.tuberculosis_H37Rv TLSLGAAGGAGGTGGAGGTVFGGGKGGAGGA------GGNAGMLFGSGGG
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu ---------DGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199 -------QANIGTS------------------------------TSAGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------LGAPRY
MMAR_0608|M.marinum_M GGAGGSGLTQGGDG------------------------------------
MUL_0570|M.ulcerans_Agy99 SGAGG---------------------------------------------
Mb0286c|M.bovis_AF2122/97 GGAGGFGFADGGQG------------------------------------
Rv1759c|M.tuberculosis_H37Rv GGTGGFGFAAGGQG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAVGGNAGLAGNAG------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GVKPTVMPKPAI--------------------------------------
MMAR_0608|M.marinum_M ------------GIGGAALGLFGAGGAGGTGGEGG---------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 ------------GPGGNAGTVFGSGGAGGNGGVG---------------Q
Rv1759c|M.tuberculosis_H37Rv ------------GVGGSAGMLSGSGGSGGAGGSGGPA------------G
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGN---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 GFAGGIGGAGGTPGLIGNGGNGGNGGASAVTGGNGGIGGTGVLIGNGGNG
Rv1759c|M.tuberculosis_H37Rv TAAGGAGGAGGAPGLIGNGGNGGNGGESGGTGGVGGAGGNAVLIGNGGEG
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 GSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQ
Rv1759c|M.tuberculosis_H37Rv GIGAL-AGKSGFGGFGGLLLGADGYNAPESTSPWHNLQQDILSFINEPTE
Mflv_5091|M.gilvum_PYR-GCK GTGG----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGG----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GDGA----------------------------------------------
TH_3810|M.thermoresistible__bu GRGG----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAG----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M -------------LFGGAGGMGGSAGMLF--------GNGGDGGAGAAA-
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 TLTGRPLIGNGANGTPGTGADGGAGGWLF--------GNGGNGGSGATG-
Rv1759c|M.tuberculosis_H37Rv ALTGRPLIGNGDSGTPGTGDDGGAGGWLF--------GNGGNGGAGAAG-
Mflv_5091|M.gilvum_PYR-GCK -TGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 -TGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 -LGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGR
TH_3810|M.thermoresistible__bu -FLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGGDG-
MAB_4284c|M.abscessus_ATCC_199 -LAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGLAGNAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------TIGNAAGNGGAGGNAGMLIGAGGAGGNGGF------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 --------TNGGDGGDGGAGGIFFGTGGTGGAGGVGTTGTGGDGGAGGAA
Rv1759c|M.tuberculosis_H37Rv --------TNGSAGGAGGAGGILFGTGGAGGAGGVGTAGAGGAGGAGGSA
Mflv_5091|M.gilvum_PYR-GCK ----------DGTGGTGGTGG----TGGQGGQGGQGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------DGLGGTGGTGG----TGGFGGQGGQGG-------------
MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNA
TH_3810|M.thermoresistible__bu --------------GNGGSAG-----------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M ------------GFSASDGGAG-------------------------GAG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 FLVGSGGNGGSGGAGLTAGGDG-------------------------GDG
Rv1759c|M.tuberculosis_H37Rv FLIGSGGTGGVGGAATTTGGVG-------------------------GAG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGQGG-LGGGGGTG-----------------------GQGGT
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGQGG-LGGVGGTG-----------------------GTGGT
MSMEG_0868|M.smegmatis_MC2_155 SGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGS
TH_3810|M.thermoresistible__bu ----RGGTGGLRGVFGINGGNG------------------------RAGL
MAB_4284c|M.abscessus_ATCC_199 ----NAAVAGNAAVAGNAAVAG------------------------NAAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M GNAGFLYGAGGAGGAGG------------------DSVGG-----ADGGD
MUL_0570|M.ulcerans_Agy99 -----------------------------------DSVGG-----ADGGD
Mb0286c|M.bovis_AF2122/97 GNAGSFFGAAGTGGAG-----------ASTKAGGTGGTGGNGGLFANGGA
Rv1759c|M.tuberculosis_H37Rv GNAGLLIGAAGLGGCGGGAFT------AGVTTGGAGGTGGAAGLFANGGA
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGT
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGT
MSMEG_0868|M.smegmatis_MC2_155 GINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVV
TH_3810|M.thermoresistible__bu GGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTPSAGFG
MAB_4284c|M.abscessus_ATCC_199 GGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGGSTAVGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M GGNGGK--------------------------------------------
MUL_0570|M.ulcerans_Agy99 GGNGGK--------------------------------------------
Mb0286c|M.bovis_AF2122/97 GGSGGLGGDAG-TGGAGGNGGLFGAGGTGGAGG----------SLGPG-A
Rv1759c|M.tuberculosis_H37Rv GGAGGTGSTAGGAGGAGGAGGLYAHGGTGGPGGNG-------GSTGAGGT
Mflv_5091|M.gilvum_PYR-GCK GGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 GGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVT
MSMEG_0868|M.smegmatis_MC2_155 NTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGN
TH_3810|M.thermoresistible__bu VPTTIQFPAGSCTSRAVSREG------------------------IMPSS
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTGVGVGSHVGG--------------------GISESLGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M ------AGLVGQGGDGGAGGNN----------------------------
MUL_0570|M.ulcerans_Agy99 ------AGLVGQGGDGGAGGNN----------------------------
Mb0286c|M.bovis_AF2122/97 GGAGGNGGLFGAGGTGGSGGHGT---------PAAVPGGAGGAGGNAGLF
Rv1759c|M.tuberculosis_H37Rv GGAGGPGGLYGAGGSGGAGGHG------------GMAGGGGGVGGNAGSL
Mflv_5091|M.gilvum_PYR-GCK GAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAG
MSMEG_0868|M.smegmatis_MC2_155 ATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAAT
TH_3810|M.thermoresistible__bu RAASARAG---------------------------AACASSTSRSRRSFC
MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGGISESLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------------------------------------------------
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 SLGASGGAGGSGGSSLTDSGGIGGVGGAGGLLFGYGGAGGAGGYSNIGAG
Rv1759c|M.tuberculosis_H37Rv TLNASGGAGGSGGSSLSGKAGAGGAGGSAGLFYGSGGAGGNGGYSLNGTG
Mflv_5091|M.gilvum_PYR-GCK AAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 SAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGAT
MSMEG_0868|M.smegmatis_MC2_155 TAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAY
TH_3810|M.thermoresistible__bu CSRA----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVGGGISESL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M --------------NSGFG------------TGGSGGKGG----------
MUL_0570|M.ulcerans_Agy99 --------------NSGFG------------TGGSGGKGG----------
Mb0286c|M.bovis_AF2122/97 GAGGAGGN---AGMLSGSGGSGGTGGASGAAKGGVGGNGG----------
Rv1759c|M.tuberculosis_H37Rv GDGGTGGAGQITGLRSGFGGAGGAGGASDTGAGGNGGAGG----------
Mflv_5091|M.gilvum_PYR-GCK GTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----------
Mvan_1264|M.vanbaalenii_PYR-1 GTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----------
MSMEG_0868|M.smegmatis_MC2_155 DPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQ
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M -DAVLIGNGG-------------------------NGGNAGSGGVGPGIA
MUL_0570|M.ulcerans_Agy99 -DAVLIGNGG-------------------------NGGNAGSGGVGPGIA
Mb0286c|M.bovis_AF2122/97 -TAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTP
Rv1759c|M.tuberculosis_H37Rv -KAGLYGNGGDGGAGGDGA-TSGKGGAGGNAVVIGNGGNGGNAGKAGGTA
Mflv_5091|M.gilvum_PYR-GCK -AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GA
Mvan_1264|M.vanbaalenii_PYR-1 -AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GA
MSMEG_0868|M.smegmatis_MC2_155 TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_0608|M.marinum_M GAAGIGGLLIGEDGMAGLTP----
MUL_0570|M.ulcerans_Agy99 GAAGIGGLLIGEDGMAGLTP----
Mb0286c|M.bovis_AF2122/97 GAGGTSGLLIGENGLNGLP-----
Rv1759c|M.tuberculosis_H37Rv GAGGAGGLVLGRDGQHGLT-----
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------
MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 ------------------------
MAV_1346|M.avium_104 ------------------------