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MSFVIAAPEVIAAAATDLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQALSAQAQ AFHAQFVQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGG AGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGG AGGFTNGSALGGAGGAGGAGGLFATGGVGGSGGAGSSGGAGGAGGAGGLFGAGGTGGHGGFADSSFGGVG GAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGGNAGMLALGAAGGAGGIGGDGGTLTAGGIGGAGGAGGNA GLLFGSGGSGGAGGFGFADGGQGGPGGNAGTVFGSGGAGGNGGVGQGFAGGIGGAGGTPGLIGNGGNGGN GGASAVTGGNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQNVLNV VNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGSGATGTNGGDGGDGGAGGIFFGTGGTGG AGGVGTTGTGGDGGAGGAAFLVGSGGNGGSGGAGLTAGGDGGDGGNAGSFFGAAGTGGAGASTKAGGTGG TGGNGGLFANGGAGGSGGLGGDAGTGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGSG GHGTPAAVPGGAGGAGGNAGLFSLGASGGAGGSGGSSLTDSGGIGGVGGAGGLLFGYGGAGGAGGYSNIG AGGAGGAGGNAGMLSGSGGSGGTGGASGAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAV LIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGLNGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0286c | PE_PGRS3 | - | 100% (877) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0768 | PE_PGRS10 | 0.0 | 72.80% (919) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0285c | PE_PGRS3a | 0.0 | 71.55% (907) | hypothetical protein Mb0285c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-161 | 45.09% (845) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0278c | PE_PGRS3 | 0.0 | 81.94% (886) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-13 | 39.56% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-49 | 32.02% (484) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4399 | - | 0.0 | 58.35% (946) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 5e-24 | 46.15% (156) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-138 | 37.72% (1071) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-42 | 42.91% (296) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 56.63% (920) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-158 | 44.90% (804) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0286c|M.bovis_AF2122/97 ----------------------------------MSFVIAAPEVIAAAAT
Rv0278c|M.tuberculosis_H37Rv ----------------------------------MSFVIAAPEVIAAAAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_4399|M.marinum_M ----------------------------------MSYVIAVPDLVAGAAS
MUL_3062|M.ulcerans_Agy99 ----------------------------------MAFVLAVPDMVAEAAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------MSIIDFILNLFR
MAV_4827|M.avium_104 ------------------------------MNIVLGVSMAPSSIQMVVLE
Mb0286c|M.bovis_AF2122/97 DLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQALS
Rv0278c|M.tuberculosis_H37Rv DLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQALS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_4399|M.marinum_M ELAGVGSTLSTATTAAAAQTTGVLAAAGDEVSAAIAAVFSAHGQSYQTLS
MUL_3062|M.ulcerans_Agy99 DLAGVGSVIDAANTAAAGSTTGIVAAAEDEVSAAIAALFSGHGQAYQQIS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQW
MAV_4827|M.avium_104 GEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLS
Mb0286c|M.bovis_AF2122/97 AQAQAFHAQFVQALTSG---------------------GGAYAAAEAAAV
Rv0278c|M.tuberculosis_H37Rv AQAQAFHAQFVQALTSG---------------------GGAYAAAEAAAV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_4399|M.marinum_M AQAETFHAQFVQALSAG---------------------ASAYTQAEAASA
MUL_3062|M.ulcerans_Agy99 TRVAEFHAQFERVFAAG---------------------VQAYSGAEAANA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VNTGNPIHDLSGN-------------------------LQNYYAAQPDGP
MAV_4827|M.avium_104 SIGVTWTDQLEAAALRD-----------------------ALAARRIDNV
Mb0286c|M.bovis_AF2122/97 S----------------------------------------PLLDPINEF
Rv0278c|M.tuberculosis_H37Rv S----------------------------------------PLLDPINEF
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_4399|M.marinum_M S----------------------------------------PLAGLLAAI
MUL_3062|M.ulcerans_Agy99 SFLQ------------------------------------DPLQTALNAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S----------------------------------------ILSPSLLSP
MAV_4827|M.avium_104 MLVS------------------------------------AFLAAAALAQ
Mb0286c|M.bovis_AF2122/97 F------------------------LANTG--------RPLIGNGANGAP
Rv0278c|M.tuberculosis_H37Rv F------------------------LANTG--------RPLIGNGANGAP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGT-
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGT-
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGT-
MMAR_4399|M.marinum_M N---------------------APVQSLTG--------RPLIGNGANGTP
MUL_3062|M.ulcerans_Agy99 N---------------------KPVQDLTG--------RPLVGNGANGVP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD------------------------------------NDFLSHNDTDFA
MAV_4827|M.avium_104 N------------------------------------VGGAMGYERTAVL
Mb0286c|M.bovis_AF2122/97 GTGANGGDGGWLIGNGGAGG-SGAAGVNG-------GAGGNGGAGGLIGN
Rv0278c|M.tuberculosis_H37Rv GTGANGGDGGWLIGNGGAGG-SGAAGVNGGA-GGNGGAGGNGGAGGLIGN
TH_3810|M.thermoresistible__bu ------------------------VDGDG-------GSGGRTGLFSKLSR
Mflv_5091|M.gilvum_PYR-GCK GQN-----GGILFGNGGSGWNSDVVGMDG-------GNGGNGGLFGG--N
Mvan_1264|M.vanbaalenii_PYR-1 GQN-----GGILFGNGGSGWNSEIAGVSG-------GNGGNAGLFGG--N
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAG-------GNGGNAGLFG---N
MMAR_4399|M.marinum_M GTGADGAPGGWLLGDGGAGG-SGAPGLNG-------GAGGAAGLLGSGGA
MUL_3062|M.ulcerans_Agy99 GTGANGAAGGWLLGNGGAGG-SGAAGQAG-------GDGGAAGLIGAGGA
MLBr_01183|M.leprae_Br4923 ----------------------------------------MPLFLNAEPQ
MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVA
MAV_4827|M.avium_104 LVEPDTATLAVVETSDGSIPDVYKQQIRAES------YGDAAGQLSAMVA
.
Mb0286c|M.bovis_AF2122/97 GGAGGAG---GVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAG
Rv0278c|M.tuberculosis_H37Rv GGAGGAG---GVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAG
TH_3810|M.thermoresistible__bu GGDGGDG-----GLGGNGGHGGGTGIISLLSLAGNGGNGGNGYR------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNG-----LGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAV
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNG-----LGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAV
MSMEG_0868|M.smegmatis_MC2_155 GGNGGVG-----WAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHV
MMAR_4399|M.marinum_M GGAGGSS---TSTNGGAGGAGGAGG--WLSGNAGVGGAGGASTVANGGAG
MUL_3062|M.ulcerans_Agy99 GGAGGNSPLRNTANGGNGGTGGAGG--LLFGPGGVGGAGGASFLT-GGTG
MLBr_01183|M.leprae_Br4923 ALTAAAN--------------------TLEGLSAATVASN----------
MAB_4284c|M.abscessus_ATCC_199 VGGSNSG-----PIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRV
MAV_4827|M.avium_104 GLEKLES-----LPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETA
. .
Mb0286c|M.bovis_AF2122/97 ----------------------GFTNGSALGGAGGAGGAGGLFATGGVGG
Rv0278c|M.tuberculosis_H37Rv GAGGAGGNAGLLFGAAGVGGAGGFTNGSALGGAGGAGGAGGLFATGGVGG
TH_3810|M.thermoresistible__bu ----------------------TTDNNALDGGHGGNGGNVGFFSLFNLGG
Mflv_5091|M.gilvum_PYR-GCK G--------------APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 G--------------APGVAGATGATGVTSNVTGGNGADAVGYGATGAAG
MSMEG_0868|M.smegmatis_MC2_155 DGG------------TGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTG
MMAR_4399|M.marinum_M G------------------AGGAGGLLGGGGLGGAGGASTSATASGGAGG
MUL_3062|M.ulcerans_Agy99 G------------------DGGAGGLFGAGGLGGVGGSGN----VGGNGG
MLBr_01183|M.leprae_Br4923 ----------------------AAAAQLTTEIAPPAADDVSILLAHFFSG
MAB_4284c|M.abscessus_ATCC_199 G---------------------GDYTNVSGHGSADIDKSVTVVDDHSQRN
MAV_4827|M.avium_104 L---------------------ARGAALAAANAPLFASSTAALAYAQDPG
.
Mb0286c|M.bovis_AF2122/97 SGGAGSSGGAGG--------------AGGAGGLFGAGGTGGHGGFADSSF
Rv0278c|M.tuberculosis_H37Rv SGGAGSSGGAGG--------------AGGAGGLFGAGGTGGHGGFADSSF
TH_3810|M.thermoresistible__bu AGGWGGSGVDG----------------VDVVGGNPDGGTPGAHG--ESHT
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGAAG--------------AVGSAGAAGEAGETGTWG--NAGL
Mvan_1264|M.vanbaalenii_PYR-1 AAGAAGAAGKAG--------------AVGSAGTAGSAGAPGVWG--NAGL
MSMEG_0868|M.smegmatis_MC2_155 AAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAG
MMAR_4399|M.marinum_M QGGAAG--LLSG--------------FVGADGGHGGAGGHGAAG-GDGGA
MUL_3062|M.ulcerans_Agy99 AGGAGG--LLAG--------------LVGAGGGDGGSGGLGAAG-GDGGN
MLBr_01183|M.leprae_Br4923 HG--------------------------RQYQAHASQGATNHQDLIQSLL
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDR--------------STNIGSGNTTNTEIGSHNQANIGT
MAV_4827|M.avium_104 TGAVDQYSLPDY------------LYVPVDPEPGDDELAYSAVGEEDAES
. .
Mb0286c|M.bovis_AF2122/97 GGVGGAGGAGG--------------LFGAGGEGGSGG--HSLVAGGDGGA
Rv0278c|M.tuberculosis_H37Rv GGVGGAGGAGG--------------LFGAGGEGGSGG--HSLVAGGDGGA
TH_3810|M.thermoresistible__bu PGVYTDR-------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK PGKAGDAGGAG----------------AVGAAGAAG------TVGTAGAT
Mvan_1264|M.vanbaalenii_PYR-1 PGAAGAAGGAG----------------AIGTAGVAG------AAGTAGAT
MSMEG_0868|M.smegmatis_MC2_155 PGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGT
MMAR_4399|M.marinum_M GGDGGPLAGAG----------------GSGGTGGSGN-----AGGGAGGA
MUL_3062|M.ulcerans_Agy99 GGRAGLFGGAG----------------GAGGMGATGG-----HSGGDGGA
MLBr_01183|M.leprae_Br4923 TSSSAYAGTET---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVG---------------------------------------
MAV_4827|M.avium_104 PTVVIEKLFLP---------------------------------------
Mb0286c|M.bovis_AF2122/97 GGNAG--------MLALGAAGGAGGIGGDGGTLTAGGIGGAGGAG-----
Rv0278c|M.tuberculosis_H37Rv GGNAG--------MLALGAAGGAGGIGGDGGTLTAGGIGGAGGAG-----
TH_3810|M.thermoresistible__bu -------------------QGEDGEDG------TGTGIGGRGGNG-----
Mflv_5091|M.gilvum_PYR-GCK GGTG---------------TGANGGAG------GVGGVGGTGAAG-----
Mvan_1264|M.vanbaalenii_PYR-1 GGTG---------------VGGNGGAG------QAGGIGGTGAAG-----
MSMEG_0868|M.smegmatis_MC2_155 GGTGRVIAEGTGSTAEGTATGGDGGHS------TGTGIGGNGGIGSVYAY
MMAR_4399|M.marinum_M GGNAG----------LLFGDGGVGGTGGT----SGQGVGGIGGDG-----
MUL_3062|M.ulcerans_Agy99 GGDAG----------LLFGTGGAGGAGGH----AFDGDGGAGGAG-----
MLBr_01183|M.leprae_Br4923 --------------------ANHDSL------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------GNAGLAG------NAGLAGNAGLAG-----
MAV_4827|M.avium_104 ---------------------EDSEPRRRPVLLVGSGLAVVGISA-----
.
Mb0286c|M.bovis_AF2122/97 -----------GNAGLLFGSGGSGGAGGFG----FADGGQGGPGGNAGTV
Rv0278c|M.tuberculosis_H37Rv -----------GNAGLLFGSGGSGGAGGFG----FADGGQGGPGGNAGTV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGG-IGGA
Mvan_1264|M.vanbaalenii_PYR-1 ---------AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGG-VGGV
MSMEG_0868|M.smegmatis_MC2_155 GNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISA-GGDG
MMAR_4399|M.marinum_M -----------GSAGLLFSNGGAGGAGGAGTALISGNGGAGGNGGNGGWL
MUL_3062|M.ulcerans_Agy99 -----------GNAGLMFSSGGSGGVGGAG----SIDGGAGGAGGDAGWL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAG------NAGLAGNAGLAGNA
MAV_4827|M.avium_104 --------------------------------------VLALEIALAIGI
Mb0286c|M.bovis_AF2122/97 FGSGGAGGNGGVG------------------------QGFAGGIGGAGGT
Rv0278c|M.tuberculosis_H37Rv FGSGGAGGNGGVG------------------------QGFAGGIGGAGGT
TH_3810|M.thermoresistible__bu GSSSGTHPMAEDG------------------------EHVKALDGRPGLD
Mflv_5091|M.gilvum_PYR-GCK GSTGAVGGVGGKG----IQGGQG-------------LQGGKGGDGGAGGK
Mvan_1264|M.vanbaalenii_PYR-1 GATGGAGGVGGKG----IQGGQG-------------LQGGQGGDGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGN
MMAR_4399|M.marinum_M FSNGGVGGAGGAGAP---------------AMPSLGISAGSGGVGGAGGT
MUL_3062|M.ulcerans_Agy99 GG-GGAGGAGGFGT----------------------ISD--GGAGGRGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG-----------------------LAGNAGLAGNAGLA
MAV_4827|M.avium_104 RTTGTVALQPTPN------------------------QHLIVPTEQAPAP
Mb0286c|M.bovis_AF2122/97 PGLIGN-------------------------GGNGGNGGASAVTGGNGG-
Rv0278c|M.tuberculosis_H37Rv PGLIGN-------------------------GGNGGNGGASAVTGGNGG-
TH_3810|M.thermoresistible__bu GG----------------------------NGSHGGNGGHGGRGGFLG--
Mflv_5091|M.gilvum_PYR-GCK GGDADSMGS------------------AGATGGKGGNGGNGGRGGLFG--
Mvan_1264|M.vanbaalenii_PYR-1 GGDATSMGE------------------AGATGGKGGNGGNGGRGSLFG--
MSMEG_0868|M.smegmatis_MC2_155 GGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSI
MMAR_4399|M.marinum_M GGLLLGNGG---------------------AGGAGGTSGNGGGTGGAGG-
MUL_3062|M.ulcerans_Agy99 GGQLLGNGG---------------------AGGAGGQGGNDGGAGGLG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GN-----------------------------AGLAGNAGLAGNAGLAGN-
MAV_4827|M.avium_104 PPVQASAPQ----------------------PKISVPEPVAAPKPLSPP-
Mb0286c|M.bovis_AF2122/97 -------------IGGTGVLIGN----------------------GGNGG
Rv0278c|M.tuberculosis_H37Rv -------------IGGTGVLIGN----------------------GGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------IGGSGG
Mflv_5091|M.gilvum_PYR-GCK -------------KGGNAGNGAD----------------------GGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -------------RGGNAGNGGN----------------------GGTGG
MSMEG_0868|M.smegmatis_MC2_155 TDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGG
MMAR_4399|M.marinum_M -------------AAGSGVLIGN----------------------GGNGG
MUL_3062|M.ulcerans_Agy99 ---------------GNGVLIGN----------------------GGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------AGLAG
MAV_4827|M.avium_104 --------------------------------------------VAAPLP
Mb0286c|M.bovis_AF2122/97 SGGIG--AGKAGVGGVSGLLLG--------LDGFNAPASTSPLHTLQQNV
Rv0278c|M.tuberculosis_H37Rv SGGIG--AGKAGVGGVSGLLLG--------LDGFNAPASTSPLHTLQQNV
TH_3810|M.thermoresistible__bu WGGHGGNGGDTDADGGNGG-------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAGGTGG-TGGAGGTGG-----------------TGGTGGIGGAGSTG
Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGTGG-TGGNGGTGG-----------------TGGTGGIGGAGSTG
MSMEG_0868|M.smegmatis_MC2_155 DGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTF
MMAR_4399|M.marinum_M IGGAGPTPGGNGIGGTSGLLLG--------LDGFNAPTSTSPIHTLQQQA
MUL_3062|M.ulcerans_Agy99 VGGVGETPGGDGGGGISGLLLG--------ADGFNAPAGSSPVHALQQQA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAGN---------------------AGLAGNAAVA
MAV_4827|M.avium_104 AAPPPAAPPLPEAPPIPAAP---------------PVVPVPVVVPPVPVP
Mb0286c|M.bovis_AF2122/97 LNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNG--GSGA
Rv0278c|M.tuberculosis_H37Rv LNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGANGTPGTGA
TH_3810|M.thermoresistible__bu -----------------------DGGNGGSAGRG----GTGGLR--GVFG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG----GTGGTG--GAGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG----GTGGTG--GDGG
MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG----GDGALG--GNGG
MMAR_4399|M.marinum_M LNAINAPIQAATGRPLIGNGTPGDAGSGTDGTPGGWLLGDGGAG--GSGG
MUL_3062|M.ulcerans_Agy99 LAAINAPVQELTGRPLIGNGLPGSAGSGAAGAPGGWLLGDGGAG--GSAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAAVAGNAAVAGNAAVG----GVLNTGVSGAIG----GSSHVG----GA
MAV_4827|M.avium_104 VPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG--GTVP
Mb0286c|M.bovis_AF2122/97 TG-------TNGGDGGD---------------------GGAGG-------
Rv0278c|M.tuberculosis_H37Rv AGGAGGWLFGNGGNGGHGATN--------TAATATGGAGGAGG-------
TH_3810|M.thermoresistible__bu IN---------------------------------GGNGRAG--------
Mflv_5091|M.gilvum_PYR-GCK TG----GDGGTGGTGGTGGTG---------GTGGTGGTGGAG--------
Mvan_1264|M.vanbaalenii_PYR-1 TG----GTGGTGGTGGTGGTG---------GTGGTGGTGGAG--------
MSMEG_0868|M.smegmatis_MC2_155 TGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGT
MMAR_4399|M.marinum_M T-------GLDGGDGGAAG------------LMGTGGTGGAGG-------
MUL_3062|M.ulcerans_Agy99 AT-----PGAAGGAGGAAG------------LVGAGGAGGAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IN---------------------------------ESLGGSGS-------
MAV_4827|M.avium_104 QS-----------------------------PPQHQTPPGEGTP------
Mb0286c|M.bovis_AF2122/97 -IFFGTGGTGGAGGVGT--TGTGGDGGAGG-----------AAFLVGSGG
Rv0278c|M.tuberculosis_H37Rv -ILFGTGGNGGTGGIATGAGGIGGAGGAGG-----------VSLLIGSGG
TH_3810|M.thermoresistible__bu ---------------------LGGRGXXXX-----------------GGG
Mflv_5091|M.gilvum_PYR-GCK ---DGTGGTGGTGG----TGGQGGQGGQGG-----------------TGG
Mvan_1264|M.vanbaalenii_PYR-1 ---DGLGGTGGTGG----TGGFGGQGGQGG-----------------TGG
MSMEG_0868|M.smegmatis_MC2_155 ATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGG
MMAR_4399|M.marinum_M -----WGGTDEITG------GTGGAGGTGGGGGWLSGSGGIGG----GGG
MUL_3062|M.ulcerans_Agy99 ------ANTGISNP------GFGGAGGAGG--------AGAGA----GGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------VGGSTAVGG--------------------
MAV_4827|M.avium_104 -------------------PKPDGPGNYGG--------------------
Mb0286c|M.bovis_AF2122/97 NGGSGGAGLTAG-------------------------GDGGDGGNAGSFF
Rv0278c|M.tuberculosis_H37Rv TGGNGGNSIGVAGIG----------------------GAGGRGGDAGLLF
TH_3810|M.thermoresistible__bu VG------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 TGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQG
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHG
MMAR_4399|M.marinum_M AGGYGGAIIPGNGGAG----------------------GSAGAGGAGGLF
MUL_3062|M.ulcerans_Agy99 VG---------------------------------------EAGGAGGLL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------GAHTGVGGGVS
MAV_4827|M.avium_104 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 GAAGTGGAGAS-TKAGGTGGTGGNGGLFANGGAGGSGGLGGDAGTGGAGG
Rv0278c|M.tuberculosis_H37Rv GAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFN---AAGGNGG
TH_3810|M.thermoresistible__bu -----------------------AAVRSGNGVFSGGGGTP---SAGFGVP
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG----------GTGGAGGDGGLGGLGGFG---GSGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG----------GTGGAGGDGGLGGLGGFG---GVGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAV--ASGIGAGGNGGDGIDGGLGGNG---GDGVVNT
MMAR_4399|M.marinum_M GGGGTGGAGGTGGPAG--LGVFVGVPTFGDGGGGGAGGAG---GAG--GL
MUL_3062|M.ulcerans_Agy99 GAGGTGGGGGVA-------------PSLVDGGTGGAGGAG---GAG--GL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGVGSHVGGG----------ISESLGGSGSVGGSTAVGGGAHTGVGGG
MAV_4827|M.avium_104 -------------------------GHVPTPGAGGSGGSG-----GGHVP
Mb0286c|M.bovis_AF2122/97 NGGLFGAGG-TGGAGGSLGPGAGGAGGNGGLFG----AGGTGGSGGHGTP
Rv0278c|M.tuberculosis_H37Rv NGGLFGTGG-TGGAGTNFG--AGGNGGNGGLFG----AGGTGGAAGSGG-
TH_3810|M.thermoresistible__bu TTIQFPAGSCTSRAVSREGIMPSSRAAS--------------ARAGAACA
Mflv_5091|M.gilvum_PYR-GCK QGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 QGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGA
MSMEG_0868|M.smegmatis_MC2_155 TANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNAT
MMAR_4399|M.marinum_M LSGLVGAGGGDGGAGGQGGIGFGGSGGSGGGGG----VGGNAGLLGGPGG
MUL_3062|M.ulcerans_Agy99 FGGIFGAGGGDGGAGGFT----GGIDGAGGVGG----AGGNTGLLGGPGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG-----GAHTGVGGGVNT
MAV_4827|M.avium_104 TPGAGGSGGSGGGHVPTPG--TGGPGGTGGSGG------GHVPTPGAGTP
Mb0286c|M.bovis_AF2122/97 AAVPGGAGGAGGNAGLFSLGASGGAGGSGGSSLTDSGGIGGVGGAGGLLF
Rv0278c|M.tuberculosis_H37Rv SGITTGGGGHGGNAGLLSLGASGGAGGSGGAS-SLAGGAGGTGGNGALLF
TH_3810|M.thermoresistible__bu SSTSRSRRSFCCSRA-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAG--
Mvan_1264|M.vanbaalenii_PYR-1 SGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAG--
MSMEG_0868|M.smegmatis_MC2_155 GTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAAT--
MMAR_4399|M.marinum_M AGGSGGAAGPALFG-IGVDGTAGVGGAGGNAGLLFGSGGAGGDGGFG---
MUL_3062|M.ulcerans_Agy99 SGGSGGD-GIAKLG-FNVDG--GAGGAGVNGGFLFGSGGTGGFGGVGGVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVG--
MAV_4827|M.avium_104 GGSGGGHLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAP--
Mb0286c|M.bovis_AF2122/97 GYGGAGGAGGYS-----NIGAGGAGGAGGNAGMLSGSGGSGGTGG----A
Rv0278c|M.tuberculosis_H37Rv GFRGAGGAGGHGGAALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 SAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGAT
MSMEG_0868|M.smegmatis_MC2_155 TAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAY
MMAR_4399|M.marinum_M --PGAGGTGGRGGNAGLLFSSAGAGGFGGYGTTGGGTGGAGGDAGWLGCG
MUL_3062|M.ulcerans_Agy99 TSTGIGGAGGRGGNAGLLFSDAGVGGFGGFG-------GTGGNAGWLGSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------GSTAVGGGAHTSAINESMNSSINASHSS
MAV_4827|M.avium_104 -----------------------GGGLGGGGGHAPAPGGGLGGFGGGHSG
Mb0286c|M.bovis_AF2122/97 SGAAKGG--------VGGNGGTAGVFGNG----GDGGAGGFG--------
Rv0278c|M.tuberculosis_H37Rv LGAGTGG--------TGGDGGHAGVFGNG----GDGGCRRVWR-------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----------
Mvan_1264|M.vanbaalenii_PYR-1 GTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----------
MSMEG_0868|M.smegmatis_MC2_155 DPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQ
MMAR_4399|M.marinum_M GAGGAGG------ITIGGTGGTGGAGGTGGQLLGAGGAGG----------
MUL_3062|M.ulcerans_Agy99 GSGGAGG------GSNG-DGGAGGTGGSGGQIVGDGGAGG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SMNESFG----------SSMGSHGAAGTG---------------------
MAV_4827|M.avium_104 GGLGGLG------------GGHK---------------------------
Mb0286c|M.bovis_AF2122/97 -----------AGTGGNGGVGGNAVLIGNGGNGGNGGKAG------GTPG
Rv0278c|M.tuberculosis_H37Rv --RYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRR------AAAR
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AGGEGGEGGDGGKGGAGAEGG-AGGGGGAGGSGAGGAG-------GAGG
Mvan_1264|M.vanbaalenii_PYR-1 -AGGEGGEGGAGGAGGDGSEGG-AGGSGGAGGSGTGGAG-------GAGG
MSMEG_0868|M.smegmatis_MC2_155 TADGEHNTGGNGGNGGDGSEPG-PGGNGAGGAGGNGGTGGTTAGGSGNGG
MMAR_4399|M.marinum_M -AGGQTDPLG-GSTGGSGGVGGNAVLIGTGGNGGNGGAG----TAKGTPG
MUL_3062|M.ulcerans_Agy99 -AGGQGDLLAAGGSGGDGGQGGDAVLIGTGGNGGNGASG----VLAGIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------FEAQGHAQGHASETAHTTLPGAEHH------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0286c|M.bovis_AF2122/97 AGGTSGLLIG-----ENGLNGLP----------------
Rv0278c|M.tuberculosis_H37Rv RERTQRLAIAGRPATTRGVEGISCSPQMMP---------
TH_3810|M.thermoresistible__bu ---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGSGG-SGGSG--GSGGAAGDSDD--------------
Mvan_1264|M.vanbaalenii_PYR-1 SGGSGG-SGGAG--GSGGAAGDSD---------------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGG-NGGAD--GTPGTAGTTGANNP-----------
MMAR_4399|M.marinum_M TGGTGG-LIGVD--GLSGAS-------------------
MUL_3062|M.ulcerans_Agy99 DGGSRGLLLGED--GVNGEAAPPMTHIVLLGGDFPAAAS
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------
MAV_4827|M.avium_104 ---------------------------------------