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STGIAMEVAFRASDVSKSFGGIRAVDGVSLEAPKGSITAIIGPNGAGKTSLFNVLTGFDQADTGEVELFG DRIEREAAWKIARRGMVRSFQTPVGFPLLSVWENLMTAGADRSESPWRALFGRRQWVEMEQQTAERAAVL LEELGLTDVKDQRLEDLTAGQTKLVDFARLLMVQPRMVLLDEPAAGVAPAGIGRLTEQVTSLRDRGITLL IIDHNIQFVFAVSDYVYVMAEGRVVASGTPDEIAVHPTVAEIYLGSAQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6877 | - | - | 100% (259) | branched-chain amino acid transport system ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_1218 | - | 4e-45 | 42.04% (245) | ABC-type transport system ATP-binding protein II |
| M. smegmatis MC2 155 | MSMEG_3250 | - | 2e-39 | 34.66% (251) | ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2961 | drrA | 7e-23 | 29.29% (239) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3571 | - | 9e-39 | 34.40% (250) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2936 | drrA | 8e-23 | 29.29% (239) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00590 | - | 1e-24 | 31.54% (241) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2623c | - | 8e-40 | 34.92% (252) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_1771 | drrA | 3e-24 | 28.27% (237) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. avium 104 | MAV_3250 | - | 2e-27 | 33.33% (237) | daunorubicin resistance ATP-binding protein DrrA |
| M. thermoresistible (build 8) | TH_3313 | - | 3e-37 | 34.00% (250) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_2014 | drrA | 4e-24 | 28.27% (237) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. vanbaalenii PYR-1 | Mvan_2844 | - | 1e-38 | 35.20% (250) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1771|M.marinum_M --------------------------------------MRNNDLAVEVRG
MUL_2014|M.ulcerans_Agy99 --------------------------------------MRNNDLAVEVRG
Mb2961|M.bovis_AF2122/97 --------------------------------------MRNDDMAVVVNG
Rv2936|M.tuberculosis_H37Rv --------------------------------------MRNDDMAVVVNG
MAV_3250|M.avium_104 --------------------------------------MSAP--AIEVEG
MLBr_00590|M.leprae_Br4923 -------------------------------MSSACTVPETPEVVIRLRG
Mflv_3571|M.gilvum_PYR-GCK MTEP----------EAFEDAVAEIAGVHRE------IRADEGEVLLQTNE
Mvan_2844|M.vanbaalenii_PYR-1 MTAPDNDATAETALENFEDSVADIAGVHRE------IQAEEGEVLLQTTD
TH_3313|M.thermoresistible__bu ------------------MSIEELAGVHRD------IRAAEGEILLETVD
MAB_2623c|M.abscessus_ATCC_199 MTKHR-DSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKD
MSMEG_6877|M.smegmatis_MC2_155 -----------------------------------MSTGIAMEVAFRASD
.
MMAR_1771|M.marinum_M VRKAFG--DVVALNDISFEVGRGEVIGLLGPNGAGKTTMVDILSTLTRPD
MUL_2014|M.ulcerans_Agy99 VRKAFG--DVVALNDISFEVGRGEVIGLLGPNGAGKTTMVDILSTLTRPD
Mb2961|M.bovis_AF2122/97 VRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNGAGKTTMVDILSTLTRPD
Rv2936|M.tuberculosis_H37Rv VRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNGAGKTTMVDILSTLTRPD
MAV_3250|M.avium_104 LTKKFG-GSTLALAGVDFSVPAGTVCGLLGHNGAGKTTTINILSTLIRPT
MLBr_00590|M.leprae_Br4923 VCKHYG--SILAVSNLDLDIHSAEVLALLGPNGAGKTTTVEMCEGFVRPD
Mflv_3571|M.gilvum_PYR-GCK LTVKFG--GLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPT
Mvan_2844|M.vanbaalenii_PYR-1 LTVKFG--GLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPT
TH_3313|M.thermoresistible__bu LTVKFG--GLVALDSVSFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPA
MAB_2623c|M.abscessus_ATCC_199 LTLKFG--GLQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPT
MSMEG_6877|M.smegmatis_MC2_155 VSKSFG--GIRAVDGVSLEAPKGSITAIIGPNGAGKTSLFNVLTGFDQAD
: :* *: : :. . : .::* ******: .: . :.
MMAR_1771|M.marinum_M AGSAHVAG--SDVVAQPAGVRRSIMVTGQQVAVDDGLTGEQNLVLFGRLY
MUL_2014|M.ulcerans_Agy99 AGSAHVAG--YDVVAQPAGVRRSIMVTGQQVAVDDGLTGEQNLVLFGRLY
Mb2961|M.bovis_AF2122/97 AGSAIIAG--YDVVSEPAGVRRSIMVTGQQVAVDDALSGEQNLVLFGRLW
Rv2936|M.tuberculosis_H37Rv AGSAIIAG--YDVVSEPAGVRRSIMVTGQQVAVDDALSGEQNLVLFGRLW
MAV_3250|M.avium_104 SGRARVAG--YDVVRQPAEVRASIGMAGQFTGMDPMLTGRENLVLFGRLR
MLBr_00590|M.leprae_Br4923 AGTIEVLG--LDPITDNARLRARIGVMLQGGGGYPAARAGEMLNLVA---
Mflv_3571|M.gilvum_PYR-GCK SGSVTFDGSTIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDAR
Mvan_2844|M.vanbaalenii_PYR-1 SGIVTFDGAPIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDAR
TH_3313|M.thermoresistible__bu SGAVIFDGQKLGRIKRHQITRLGIARTFQNIRLWGEMTALENVVVGTDAR
MAB_2623c|M.abscessus_ATCC_199 SGSIVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVGTDAR
MSMEG_6877|M.smegmatis_MC2_155 TGEVELFGDRIEREAAWKIARRGMVRSFQTPVGFPLLSVWENLMTAGADR
:* . * * : * : :
MMAR_1771|M.marinum_M G---------------LRKSRARQRAQELLDQFGLTYAGKRLVRTYSGGM
MUL_2014|M.ulcerans_Agy99 G---------------LRKSRARQRAQELLDQFGLTYAGKRLVRTYSGGM
Mb2961|M.bovis_AF2122/97 G---------------LSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGM
Rv2936|M.tuberculosis_H37Rv G---------------LSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGM
MAV_3250|M.avium_104 G---------------LNRRRAKARADELLEQFNLVDAADRRLSTYSGGM
MLBr_00590|M.leprae_Br4923 -----------------SYAADPLDPEWLLETLGLTDVARTTYRRLSGGQ
Mflv_3571|M.gilvum_PYR-GCK HHTSVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGD
Mvan_2844|M.vanbaalenii_PYR-1 HHTSVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGD
TH_3313|M.thermoresistible__bu HKTSVPGALFRSPRHRREERSAIERATALLHFVGIAHRAEEKAKNLPYGD
MAB_2623c|M.abscessus_ATCC_199 HKTSVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGS
MSMEG_6877|M.smegmatis_MC2_155 SESPWR-ALFGRRQWVEMEQQTAERAAVLLEELGLTDVKDQRLEDLTAGQ
**. ..:. . *
MMAR_1771|M.marinum_M RRRIDIACGLVVEPQVAFLDEPTTGLDPRSRQAIWDLVTSFKKLGIATLL
MUL_2014|M.ulcerans_Agy99 RRRIDIACGLVVEPQVAFLDEPTTGLDPRSRQAIWDLVTSFKKLGIATLL
Mb2961|M.bovis_AF2122/97 RRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKKLGIATLL
Rv2936|M.tuberculosis_H37Rv RRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKKLGIATLL
MAV_3250|M.avium_104 YRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVSSLRVQGISVLL
MLBr_00590|M.leprae_Br4923 QQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVVL
Mflv_3571|M.gilvum_PYR-GCK QRRLEIARALATEPKLLCLDEPAAGFNPSEKSALIDLIRKIRDDGYTVLL
Mvan_2844|M.vanbaalenii_PYR-1 QRRLEIARALATEPKLLCLDEPAAGFNPSEKSALIELIRKIRDDGYTVLL
TH_3313|M.thermoresistible__bu QRRLEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDGYTVLL
MAB_2623c|M.abscessus_ATCC_199 QRRLEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYGYTVLL
MSMEG_6877|M.smegmatis_MC2_155 TKLVDFARLLMVQPRMVLLDEPAAGVAPAGIGRLTEQVTSLRDRGITLLI
: : :* * *.: ****::*. . : : :: * : ::
MMAR_1771|M.marinum_M TTQYLEEADALSDRIILIDHGKIIADGTANELKHRAGDTFCEIVPRHLKD
MUL_2014|M.ulcerans_Agy99 TTQYLEEADALSDRIILIDHGKIIADGTANELKHRAGDTFCEIVPRHLKD
Mb2961|M.bovis_AF2122/97 TTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDTFCEIVPRDLKD
Rv2936|M.tuberculosis_H37Rv TTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDTFCEIVPRDLKD
MAV_3250|M.avium_104 TTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTSYCQVTPANPAE
MLBr_00590|M.leprae_Br4923 TTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRLD
Mflv_3571|M.gilvum_PYR-GCK IEHDMRLVMGVTDRIVVLEFGRKIADGLPSEIREDPKVIAAYLGVPDDEL
Mvan_2844|M.vanbaalenii_PYR-1 IEHDMRLVMGVTDRIVVLEFGRKIADGLPAEIREDPKVIAAYLGVPDDEL
TH_3313|M.thermoresistible__bu IEHDMKLVMGVTDRIVVLEFGRKIADGPPAAIREDPAVIAAYLGVPDDEI
MAB_2623c|M.abscessus_ATCC_199 IEHDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPAVIEAYLGVADEDF
MSMEG_6877|M.smegmatis_MC2_155 IDHNIQFVFAVSDYVYVMAEGRVVASGTPDEIAVHPTVAEIYLGSAQ---
: :. . ::* : :: * :* * . : .
MMAR_1771|M.marinum_M LDATVAALGSLLPEHNRAMVTSESDRITMPAPDGTRTLIEAARRIDEANI
MUL_2014|M.ulcerans_Agy99 LDATVAALGSLLPEHNRAMVTSESDRITMPAPDGTRTLIEAARKIDEANI
Mb2961|M.bovis_AF2122/97 LDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLVEAARRIDEARI
Rv2936|M.tuberculosis_H37Rv LDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLVEAARRIDEARI
MAV_3250|M.avium_104 LPQVAAALTGLEG----IEIDSDTGSVSVFAPDGVATLVEVFRRVDALGL
MLBr_00590|M.leprae_Br4923 LSLLAFALP-----EDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINV
Mflv_3571|M.gilvum_PYR-GCK A-------------------------------------------------
Mvan_2844|M.vanbaalenii_PYR-1 T-------------------------------------------------
TH_3313|M.thermoresistible__bu G-------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 HGPGWLDSAPPDSESER---------------------------------
MSMEG_6877|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1771|M.marinum_M ELADIALRRPSLDDVFLSMTTDPSEAHALSHVASGAML
MUL_2014|M.ulcerans_Agy99 ELADIALRRPSLDDVFLSMTTDPSEAHVLSHVASGAML
Mb2961|M.bovis_AF2122/97 ELADIALRRPSLDDVFLAMTTDPTES--LTHLVSGSAR
Rv2936|M.tuberculosis_H37Rv ELADIALRRPSLDHVFLAMTTDPTES--LTHLVSGSAR
MAV_3250|M.avium_104 ELADISLRKPSLDEAFLHLTER---------TVARS--
MLBr_00590|M.leprae_Br4923 LTTNMRVEQHSLEDVFLDLTGRKLR-------------
Mflv_3571|M.gilvum_PYR-GCK --------------------------------------
Mvan_2844|M.vanbaalenii_PYR-1 --------------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------
MSMEG_6877|M.smegmatis_MC2_155 --------------------------------------