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MTAPDNDATAETALENFEDSVADIAGVHREIQAEEGEVLLQTTDLTVKFGGLTALDAVTFNIRRGEILGL IGPNGAGKTTCFNAITGVYRPTSGIVTFDGAPIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTD ARHHTSVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGDQRRLEIARALATEPKLLC LDEPAAGFNPSEKSALIELIRKIRDDGYTVLLIEHDMRLVMGVTDRIVVLEFGRKIADGLPAEIREDPKV IAAYLGVPDDELT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2844 | - | - | 100% (293) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2593 | - | 3e-35 | 37.05% (251) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | 2e-34 | 35.16% (256) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-27 | 30.49% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3571 | - | 1e-150 | 95.02% (281) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-27 | 30.49% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_02352 | - | 9e-25 | 28.15% (238) | putative antibiotic resistance efflux protein |
| M. abscessus ATCC 19977 | MAB_2623c | - | 1e-113 | 78.21% (257) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3263 | - | 4e-29 | 34.45% (238) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1785 | - | 6e-28 | 30.08% (256) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_3250 | - | 1e-142 | 90.91% (275) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_3313 | - | 1e-136 | 87.55% (273) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3577 | - | 8e-29 | 34.45% (238) | ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 -------------------------MT---------------YAIVVADA
Rv2397c|M.tuberculosis_H37Rv -------------------------MT---------------YAIVVADA
MAV_1785|M.avium_104 -------------------------MTDAGT-------DRGDIAITVRDA
Mvan_2844|M.vanbaalenii_PYR-1 MTAPDNDAT--AETALENFEDSVADIAGVHR---EIQAEEGEVLLQTTDL
Mflv_3571|M.gilvum_PYR-GCK MTEP------------EAFEDAVAEIAGVHR---EIRADEGEVLLQTNEL
MSMEG_3250|M.smegmatis_MC2_155 MTEPP-----------QVAEEVIEDLAGVHR---EINAAEGEILLQTHDL
TH_3313|M.thermoresistible__bu --------------------MSIEELAGVHR---DIRAAEGEILLETVDL
MAB_2623c|M.abscessus_ATCC_199 MTKHRDSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKDL
MMAR_3263|M.marinum_M -----------------------------------MRRSQSAVEVIDLVK
MUL_3577|M.ulcerans_Agy99 -----------------------------------MRRSQSAVEVIDLVK
MLBr_02352|M.leprae_Br4923 -----------------------------------MRNNDKAVMVRGVRK
:
Mb2419c|M.bovis_AF2122/97 TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
Rv2397c|M.tuberculosis_H37Rv TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
MAV_1785|M.avium_104 YKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
Mvan_2844|M.vanbaalenii_PYR-1 TVKFGGLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPTSGI
Mflv_3571|M.gilvum_PYR-GCK TVKFGGLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPTSGS
MSMEG_3250|M.smegmatis_MC2_155 TVKFGGLVALDSVNFGIRRGEILGLIGPNGAGKTTCFNAITGVYRPSSGS
TH_3313|M.thermoresistible__bu TVKFGGLVALDSVSFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPASGA
MAB_2623c|M.abscessus_ATCC_199 TLKFGGLQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPTSGS
MMAR_3263|M.marinum_M --RRGSVTAVDGISFAVPPGGVLGLLGPNGAGKTTTVRMLATLTRPTSGA
MUL_3577|M.ulcerans_Agy99 --RRGSVTAVDGISFAVPQGGILGLLGPNGAGKTTTVRMVATLTRPTSGT
MLBr_02352|M.leprae_Br4923 TYGKGKIIALDDVSFDVDRGEVIGLLGPNGAGKTTMVDILSTLTRPDRGL
* . *:* : * : * : .*:**.*:**:* . :: : :* *
Mb2419c|M.bovis_AF2122/97 ITINGRDVTRVP---PQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRP
Rv2397c|M.tuberculosis_H37Rv ITINGRDVTRVP---PQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRP
MAV_1785|M.avium_104 VTIYGRDVTRVP---PQRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRKRP
Mvan_2844|M.vanbaalenii_PYR-1 VTFDGAPIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDARHHT
Mflv_3571|M.gilvum_PYR-GCK VTFDGSTIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDARHHT
MSMEG_3250|M.smegmatis_MC2_155 VTFDGAPLGRIKRHQITRRGIARTFQNIRLFGEMTALENVMVGTDARHRT
TH_3313|M.thermoresistible__bu VIFDGQKLGRIKRHQITRLGIARTFQNIRLWGEMTALENVVVGTDARHKT
MAB_2623c|M.abscessus_ATCC_199 IVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVGTDARHKT
MMAR_3263|M.marinum_M AWVAGHDVCAAP--ESVRREIGLTCQEATLDGLLTARENINMIGSLRGIR
MUL_3577|M.ulcerans_Agy99 AWVAGHDVCTAP--ESVRREIGLTCQEATLDGLLTARENINMIGSLRGIR
MLBr_02352|M.leprae_Br4923 ATVAGYDVVSEP--AGVRRSIMVTGQQVAVDDQLSGEQNLILFGRLYGLS
. * : * * . *. :: :*:
Mb2419c|M.bovis_AF2122/97 ------------KAEIKAKVDN---LLQVVGLSGFQSRYPNQLSGGQRQR
Rv2397c|M.tuberculosis_H37Rv ------------KAEIKAKVDN---LLQVVGLSGFQSRYPNQLSGGQRQR
MAV_1785|M.avium_104 ------------KAEIKAKVDN---LLEVVGLSGFQGRYPNQLSGGQRQR
Mvan_2844|M.vanbaalenii_PYR-1 SVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGDQRR
Mflv_3571|M.gilvum_PYR-GCK SVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGDQRR
MSMEG_3250|M.smegmatis_MC2_155 SVPGALIRSPRHFREERSAVERSAALLHFVGIAHRGEEKAKNLSYGDQRR
TH_3313|M.thermoresistible__bu SVPGALFRSPRHRREERSAIERATALLHFVGIAHRAEEKAKNLPYGDQRR
MAB_2623c|M.abscessus_ATCC_199 SVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGSQRR
MMAR_3263|M.marinum_M ------------RKELASLTDR---LLDQFSIAEFADRRVDTYSGGMRRR
MUL_3577|M.ulcerans_Agy99 ------------RKELASLSDR---LLDQFSIAEFADRRVDTYSGGMRRR
MLBr_02352|M.leprae_Br4923 ------------KSVARVRTQE---LLEQFDLLHAGKRRVGTYSGGMRRR
: **. ..: . * ::*
Mb2419c|M.bovis_AF2122/97 MALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVT
Rv2397c|M.tuberculosis_H37Rv MALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVT
MAV_1785|M.avium_104 MALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVT
Mvan_2844|M.vanbaalenii_PYR-1 LEIARALATEPKLLCLDEPAAGFNPSEKSALIELIRKIRDDG-YTVLLIE
Mflv_3571|M.gilvum_PYR-GCK LEIARALATEPKLLCLDEPAAGFNPSEKSALIDLIRKIRDDG-YTVLLIE
MSMEG_3250|M.smegmatis_MC2_155 LEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDG-YTVLLIE
TH_3313|M.thermoresistible__bu LEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDG-YTVLLIE
MAB_2623c|M.abscessus_ATCC_199 LEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYG-YTVLLIE
MMAR_3263|M.marinum_M LDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLRTLVDDG-LTLVLTT
MUL_3577|M.ulcerans_Agy99 LDVAISLLARPQVLFLDEPTAGLDPHSRIQLWEVLGTLVDDG-PTLVLTT
MLBr_02352|M.leprae_Br4923 IDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKQIG-IATLLTT
: :* .* . *:: **** .: . : : : : : : :*
Mb2419c|M.bovis_AF2122/97 HDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLN
Rv2397c|M.tuberculosis_H37Rv HDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLN
MAV_1785|M.avium_104 HDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLGAVSTLN
Mvan_2844|M.vanbaalenii_PYR-1 HDMRLVMGVTDRIVVLEFGRKIADGLPAEIREDPK--VIAAYLGVPDDEL
Mflv_3571|M.gilvum_PYR-GCK HDMRLVMGVTDRIVVLEFGRKIADGLPSEIREDPK--VIAAYLGVPDDEL
MSMEG_3250|M.smegmatis_MC2_155 HDMRLVMGVTDRIVVLEFGRKIADGLPSQIREDPK--VIAAYLGVPDDEI
TH_3313|M.thermoresistible__bu HDMKLVMGVTDRIVVLEFGRKIADGPPAAIREDPA--VIAAYLGVPDDEI
MAB_2623c|M.abscessus_ATCC_199 HDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPA--VIEAYLGVADEDF
MMAR_3263|M.marinum_M QYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIVVTVSRTEDVA
MUL_3577|M.ulcerans_Agy99 QYLEEADRLADNIVLIDKGRVIAEGSPFELKQKAGDASIVVTVSRTEDVA
MLBr_02352|M.leprae_Br4923 QYLEEADELSDRIILIDHGTVIAEGTASELKHRVGETFCEIVPRDLKDLG
: . ::*.* ::. * * . : . .
Mb2419c|M.bovis_AF2122/97 GSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVEL
Rv2397c|M.tuberculosis_H37Rv GSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVEL
MAV_1785|M.avium_104 GTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDRVVKLGFEVRVEL
Mvan_2844|M.vanbaalenii_PYR-1 T-------------------------------------------------
Mflv_3571|M.gilvum_PYR-GCK A-------------------------------------------------
MSMEG_3250|M.smegmatis_MC2_155 R-------------------------------------------------
TH_3313|M.thermoresistible__bu G-------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 HGPGWLDSAPPDSESER---------------------------------
MMAR_3263|M.marinum_M NVAAFLRTGAKEVR---VDISARRITV-ATHGLLDLSDVARMLHQYAAPI
MUL_3577|M.ulcerans_Agy99 NVAAFLRTGVKEVR---VDICARRITV-ATHGLLDLSEVARMLHHYAAPV
MLBr_02352|M.leprae_Br4923 TVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLIEAARRIDEVSVEL
Mb2419c|M.bovis_AF2122/97 TSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG---VSGVD
Rv2397c|M.tuberculosis_H37Rv TSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG---VSGVD
MAV_1785|M.avium_104 TSAATGGPFTAQITRGDAEALALREGDTVYVRATRVPPITAGATTVPAVS
Mvan_2844|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3571|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3250|M.smegmatis_MC2_155 --------------------------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3263|M.marinum_M EDIRLTRPSLDDVFVLLTGHHGSSSEGD------------SA--------
MUL_3577|M.ulcerans_Agy99 EDIRLARPSLDDVFVLLTGHHSSSSEGDGRLGAWPALVAGSAEHARGVRS
MLBr_02352|M.leprae_Br4923 ADIALRRPSLDDVFLSMTTDPSESLSHL------------AAGAMR----
Mb2419c|M.bovis_AF2122/97 DAGVERVKVTST--------------------------------------
Rv2397c|M.tuberculosis_H37Rv DAGVERVKVTST--------------------------------------
MAV_1785|M.avium_104 RDGADEATLTSA--------------------------------------
Mvan_2844|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3571|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3250|M.smegmatis_MC2_155 --------------------------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3263|M.marinum_M --------------------------------------------------
MUL_3577|M.ulcerans_Agy99 CARSGRGVLWRSSTLHQLCCGETGNRLARVRWGWRVGLSAGLRRRTRRGR
MLBr_02352|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 ----------------------
Rv2397c|M.tuberculosis_H37Rv ----------------------
MAV_1785|M.avium_104 ----------------------
Mvan_2844|M.vanbaalenii_PYR-1 ----------------------
Mflv_3571|M.gilvum_PYR-GCK ----------------------
MSMEG_3250|M.smegmatis_MC2_155 ----------------------
TH_3313|M.thermoresistible__bu ----------------------
MAB_2623c|M.abscessus_ATCC_199 ----------------------
MMAR_3263|M.marinum_M ----------------------
MUL_3577|M.ulcerans_Agy99 RAPRNRAASTGLGGLTRVRRRW
MLBr_02352|M.leprae_Br4923 ----------------------