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MTEPPQVAEEVIEDLAGVHREINAAEGEILLQTHDLTVKFGGLVALDSVNFGIRRGEILGLIGPNGAGKT TCFNAITGVYRPSSGSVTFDGAPLGRIKRHQITRRGIARTFQNIRLFGEMTALENVMVGTDARHRTSVPG ALIRSPRHFREERSAVERSAALLHFVGIAHRGEEKAKNLSYGDQRRLEIARALATEPKLLCLDEPAAGFN PSEKAALIDLIRKIRDDGYTVLLIEHDMRLVMGVTDRIVVLEFGRKIADGLPSQIREDPKVIAAYLGVPD DEIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3250 | - | - | 100% (284) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_1218 | - | 8e-44 | 37.15% (253) | ABC-type transport system ATP-binding protein II |
| M. smegmatis MC2 155 | MSMEG_6877 | - | 3e-39 | 34.66% (251) | branched-chain amino acid transport system ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-29 | 32.11% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3571 | - | 1e-143 | 89.40% (283) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 4e-29 | 32.11% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_02352 | - | 6e-26 | 29.96% (227) | putative antibiotic resistance efflux protein |
| M. abscessus ATCC 19977 | MAB_2623c | - | 1e-112 | 76.25% (261) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 7e-29 | 32.52% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 2e-29 | 31.89% (254) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_3313 | - | 1e-137 | 89.71% (272) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-29 | 32.52% (246) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2844 | - | 1e-142 | 90.91% (275) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 -------------------------MT---------------YAIVVADA
Rv2397c|M.tuberculosis_H37Rv -------------------------MT---------------YAIVVADA
MMAR_3715|M.marinum_M -------------------MKKETSLTGPGT---------GGHAIVVRDA
MUL_3658|M.ulcerans_Agy99 -------------------------MTGPGT---------GGHAIVVRDA
MAV_1785|M.avium_104 -------------------------MTDAGTD-------RGDIAITVRDA
Mflv_3571|M.gilvum_PYR-GCK MTEP------------EAFEDAVAEIAGVHR---EIRADEGEVLLQTNEL
Mvan_2844|M.vanbaalenii_PYR-1 MTAPDNDAT--AETALENFEDSVADIAGVHR---EIQAEEGEVLLQTTDL
MSMEG_3250|M.smegmatis_MC2_155 MTEPP-----------QVAEEVIEDLAGVHR---EINAAEGEILLQTHDL
TH_3313|M.thermoresistible__bu --------------------MSIEELAGVHR---DIRAAEGEILLETVDL
MAB_2623c|M.abscessus_ATCC_199 MTKHRDSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKDL
MLBr_02352|M.leprae_Br4923 -------------------------MRNNDK----------AVMVRGVRK
:
Mb2419c|M.bovis_AF2122/97 TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
Rv2397c|M.tuberculosis_H37Rv TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
MMAR_3715|M.marinum_M FKQYGDFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGN
MUL_3658|M.ulcerans_Agy99 FKQYGDFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGN
MAV_1785|M.avium_104 YKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
Mflv_3571|M.gilvum_PYR-GCK TVKFGGLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPTSGS
Mvan_2844|M.vanbaalenii_PYR-1 TVKFGGLTALDAVTFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPTSGI
MSMEG_3250|M.smegmatis_MC2_155 TVKFGGLVALDSVNFGIRRGEILGLIGPNGAGKTTCFNAITGVYRPSSGS
TH_3313|M.thermoresistible__bu TVKFGGLVALDSVSFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPASGA
MAB_2623c|M.abscessus_ATCC_199 TLKFGGLQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPTSGS
MLBr_02352|M.leprae_Br4923 TYGKGKIIALDDVSFDVDRGEVIGLLGPNGAGKTTMVDILSTLTRPDRGL
* : *** * * : *.: .*:**.*:**:* . :: : :* *
Mb2419c|M.bovis_AF2122/97 ITING---RDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK--
Rv2397c|M.tuberculosis_H37Rv ITING---RDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK--
MMAR_3715|M.marinum_M ITING---RDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK--
MUL_3658|M.ulcerans_Agy99 ITING---RDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK--
MAV_1785|M.avium_104 VTIYG---RDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRK--
Mflv_3571|M.gilvum_PYR-GCK VTFDGSTIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDARHHT
Mvan_2844|M.vanbaalenii_PYR-1 VTFDGAPIGRIKRHQITRLGIARTFQNIRLFGEMTALENVMVGTDARHHT
MSMEG_3250|M.smegmatis_MC2_155 VTFDGAPLGRIKRHQITRRGIARTFQNIRLFGEMTALENVMVGTDARHRT
TH_3313|M.thermoresistible__bu VIFDGQKLGRIKRHQITRLGIARTFQNIRLWGEMTALENVVVGTDARHKT
MAB_2623c|M.abscessus_ATCC_199 IVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVGTDARHKT
MLBr_02352|M.leprae_Br4923 ATVAG--YDVVSEPAGVRRSIMVTGQQVAVDDQLSGEQNLILFGRLYG--
. * : . * .* . *: .:: :*:
Mb2419c|M.bovis_AF2122/97 ----------RPKAEIKAKVDN---LLQVVGLSGFQSRYPNQLSGGQRQR
Rv2397c|M.tuberculosis_H37Rv ----------RPKAEIKAKVDN---LLQVVGLSGFQSRYPNQLSGGQRQR
MMAR_3715|M.marinum_M ----------RPKAEIRDKVDN---LLEVVGLSGFHGRYPNQLSGGQRQR
MUL_3658|M.ulcerans_Agy99 ----------RPKAEIRDKVDN---LLEVVGLSGFHGRYPDQLSGGQRQR
MAV_1785|M.avium_104 ----------RPKAEIKAKVDN---LLEVVGLSGFQGRYPNQLSGGQRQR
Mflv_3571|M.gilvum_PYR-GCK SVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGDQRR
Mvan_2844|M.vanbaalenii_PYR-1 SVPGALIRSPRHRREERSAIERSAALLHFVGIAHRGEEKAKNLSYGDQRR
MSMEG_3250|M.smegmatis_MC2_155 SVPGALIRSPRHFREERSAVERSAALLHFVGIAHRGEEKAKNLSYGDQRR
TH_3313|M.thermoresistible__bu SVPGALFRSPRHRREERSAIERATALLHFVGIAHRAEEKAKNLPYGDQRR
MAB_2623c|M.abscessus_ATCC_199 SVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGSQRR
MLBr_02352|M.leprae_Br4923 ----------LSKSVARVRTQE---LLEQFDLLHAGKRRVGTYSGGMRRR
: : **. ..: . * ::*
Mb2419c|M.bovis_AF2122/97 MALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVT
Rv2397c|M.tuberculosis_H37Rv MALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVT
MMAR_3715|M.marinum_M MALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVT
MUL_3658|M.ulcerans_Agy99 MALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVT
MAV_1785|M.avium_104 MALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVT
Mflv_3571|M.gilvum_PYR-GCK LEIARALATEPKLLCLDEPAAGFNPSEKSALIDLIRKIRDDG-YTVLLIE
Mvan_2844|M.vanbaalenii_PYR-1 LEIARALATEPKLLCLDEPAAGFNPSEKSALIELIRKIRDDG-YTVLLIE
MSMEG_3250|M.smegmatis_MC2_155 LEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDG-YTVLLIE
TH_3313|M.thermoresistible__bu LEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDG-YTVLLIE
MAB_2623c|M.abscessus_ATCC_199 LEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYG-YTVLLIE
MLBr_02352|M.leprae_Br4923 IDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKQIG-IATLLTT
: :* .*..:*:: **** .: . : : : ::: :.:*
Mb2419c|M.bovis_AF2122/97 HDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLN
Rv2397c|M.tuberculosis_H37Rv HDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLN
MMAR_3715|M.marinum_M HDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFLGAVSALN
MUL_3658|M.ulcerans_Agy99 HDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLGAVSALN
MAV_1785|M.avium_104 HDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLGAVSTLN
Mflv_3571|M.gilvum_PYR-GCK HDMRLVMGVTDRIVVLEFGRKIADGLPSEIREDPK--VIAAYLGVPDDEL
Mvan_2844|M.vanbaalenii_PYR-1 HDMRLVMGVTDRIVVLEFGRKIADGLPAEIREDPK--VIAAYLGVPDDEL
MSMEG_3250|M.smegmatis_MC2_155 HDMRLVMGVTDRIVVLEFGRKIADGLPSQIREDPK--VIAAYLGVPDDEI
TH_3313|M.thermoresistible__bu HDMKLVMGVTDRIVVLEFGRKIADGPPAAIREDPA--VIAAYLGVPDDEI
MAB_2623c|M.abscessus_ATCC_199 HDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPA--VIEAYLGVADEDF
MLBr_02352|M.leprae_Br4923 QYLEEADELSDRIILIDHGTVIAEGTASELKHRVGETFCEIVPRDLKDLG
: . ::*** ::. * * .: : . . .
Mb2419c|M.bovis_AF2122/97 GSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVEL
Rv2397c|M.tuberculosis_H37Rv GSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVEL
MMAR_3715|M.marinum_M GALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVEL
MUL_3658|M.ulcerans_Agy99 GALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVEL
MAV_1785|M.avium_104 GTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDRVVKLGFEVRVEL
Mflv_3571|M.gilvum_PYR-GCK A-------------------------------------------------
Mvan_2844|M.vanbaalenii_PYR-1 T-------------------------------------------------
MSMEG_3250|M.smegmatis_MC2_155 R-------------------------------------------------
TH_3313|M.thermoresistible__bu G-------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 HGPGWLDSAPPDSESER---------------------------------
MLBr_02352|M.leprae_Br4923 TVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLIEAARRIDEVSVEL
Mb2419c|M.bovis_AF2122/97 TSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVD
Rv2397c|M.tuberculosis_H37Rv TSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVD
MMAR_3715|M.marinum_M TSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVP
MUL_3658|M.ulcerans_Agy99 TSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVP
MAV_1785|M.avium_104 TSAATGGPFTAQITRGDAEALALREGDTVYVRATRVPPITAGATTVPAVS
Mflv_3571|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2844|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3250|M.smegmatis_MC2_155 --------------------------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02352|M.leprae_Br4923 ADIALR----------------RPSLDDVFLSMTTDPSESLSHLAAGAMR
Mb2419c|M.bovis_AF2122/97 DAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv DAGVERVKVTST------
MMAR_3715|M.marinum_M DDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 DDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 RDGADEATLTSA------
Mflv_3571|M.gilvum_PYR-GCK ------------------
Mvan_2844|M.vanbaalenii_PYR-1 ------------------
MSMEG_3250|M.smegmatis_MC2_155 ------------------
TH_3313|M.thermoresistible__bu ------------------
MAB_2623c|M.abscessus_ATCC_199 ------------------
MLBr_02352|M.leprae_Br4923 ------------------