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MSTSLVHTDVADGVFTLTLDAPDTGNALDVAMTNAVANALERANAMPDVHCVLIRSSGRHFCTGGNVKDM ARGTDLMAGTAAEVQHRLRAGLHRITRALHGLEVPSVAAVNGAAVGAGFDLALMCDVRIAAQSARFAESF LRLGLVSGIGGAWFLTRIVGVAKAMELTLTSEFITAETAHELRIVSRVVPDEDLDQECLALAHTVAANPP QALRMAKRLVRESAESGLPAALEMAASMQAILLCGDEHRSRVQQFLAARN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6774 | - | - | 100% (260) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_3390 | - | 2e-52 | 44.27% (253) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2880 | - | 1e-51 | 45.61% (239) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 5e-33 | 37.83% (230) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2444 | - | 2e-33 | 35.29% (238) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 5e-33 | 37.83% (230) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-32 | 38.60% (228) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 9e-33 | 33.88% (245) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_3510 | echA8_5 | 9e-52 | 45.64% (241) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_2641 | - | 2e-33 | 33.07% (254) | enoyl CoA hydratase |
| M. thermoresistible (build 8) | TH_2877 | - | 2e-36 | 39.04% (228) | PUTATIVE putative enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 2e-51 | 45.64% (241) | enoyl-CoA hydratase, EchA8_5 |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 4e-51 | 45.02% (251) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2641|M.avium_104 -------------MNTQAAVLSDIADGVLTITLNRPEAANAVR-PDDRDA
TH_2877|M.thermoresistible__bu --------------VSATGLSARTEDGVRWLVLDRPDVGNSVT-RAMQRD
Mflv_2444|M.gilvum_PYR-GCK -------------MADTEVLLSSDRDGVRTLTLNRPHRRNALD-ARLWVE
MAB_0905|M.abscessus_ATCC_1997 ----------MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALD-RTMKTE
MMAR_3510|M.marinum_M -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGKDFIAA
MUL_2758|M.ulcerans_Agy99 -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGRDFIAA
Mvan_2877|M.vanbaalenii_PYR-1 MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAA
MSMEG_6774|M.smegmatis_MC2_155 -------------MSTS-LVHTDVADGVFTLTLDAPDTGNALD-VAMTNA
Mb1099c|M.bovis_AF2122/97 --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
Rv1070c|M.tuberculosis_H37Rv --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
MLBr_02402|M.leprae_Br4923 --------------MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNE
: .:: *. *::
MAV_2641|M.avium_104 LIALLAAADADEKVRVVVLRANG-KHFCSGADVGSLAERRARGEKRVLEP
TH_2877|M.thermoresistible__bu LIDNLERASADPDIRAVVFTAAGTKHFCTGPNLRD-PEMRPSQDRIAGDA
Mflv_2444|M.gilvum_PYR-GCK LADALRALKREQDVRALVLTGAG-GAFCSGADIGTGEQIH---PRYKLDR
MAB_0905|M.abscessus_ATCC_1997 LLQALLAAGGDPAVRAVVMSAAG-KNFCVGQDLAEHVEALRDDPAHAMDT
MMAR_3510|M.marinum_M FEAAVDDANIDTSVRAVILTGAG-KIFSGGGNVKEMANRDGMFGLDALEQ
MUL_2758|M.ulcerans_Agy99 FEAAVDDANIDTSVRAVILTGAG-KIFSGGGNVKEMANRDGMFGLDALEQ
Mvan_2877|M.vanbaalenii_PYR-1 FESAVDTANSDVAVRAVILTGAG-KIFSAGGNVKEMADRQGMFGLDAIAQ
MSMEG_6774|M.smegmatis_MC2_155 VANALERANAMPDVHCVLIRSSG-RHFCTGGNVKDMARGTDLMAGTAAEV
Mb1099c|M.bovis_AF2122/97 VTSAATELDDDPDIGAIIITGSA-KAFAAGADIKEMAD---------LTF
Rv1070c|M.tuberculosis_H37Rv VTSAATELDDDPDIGAIIITGSA-KAFAAGADIKEMAD---------LTF
MLBr_02402|M.leprae_Br4923 ITNAAKELDIDPDVGAILITGSP-KVFAAGADIKEMAS---------LTF
. : ::: . *. * ::
MAV_2641|M.avium_104 TRRIMNGAQKLVASVLDCNKPVIAAVHGAATGLGAHVVYASDLVIATENA
TH_2877|M.thermoresistible__bu ARRLRTGSQAVVSAILDCEKPVVCGLNGVAAGVGASMVLACDLIVAAESA
Mflv_2444|M.gilvum_PYR-GCK LTD-------VALALHELAIPTIAKVTGIAVGAGWNLALGCDLVVATPES
MAB_0905|M.abscessus_ATCC_1997 VREHYN---PVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRA
MMAR_3510|M.marinum_M RQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRA
MUL_2758|M.ulcerans_Agy99 RQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRA
Mvan_2877|M.vanbaalenii_PYR-1 RHAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCDIRVASERA
MSMEG_6774|M.smegmatis_MC2_155 QHRLRAGLHRITRALHGLEVPSVAAVNGAAVGAGFDLALMCDVRIAAQSA
Mb1099c|M.bovis_AF2122/97 ADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTA
Rv1070c|M.tuberculosis_H37Rv ADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTA
MLBr_02402|M.leprae_Br4923 TDAFDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTA
: * : : * . * * :. .*: :* :
MAV_2641|M.avium_104 YFAESFVKRGLVVDGGGCYLLPRRIGMQKAKEMAFFGEKLSATEAFTLGL
TH_2877|M.thermoresistible__bu RLIELFVRRGLAPDGGAAYLLARKVPFNIAKELLMFGEQITAQEAHRIGL
Mflv_2444|M.gilvum_PYR-GCK RFCQIFSKRGLSVDLGGSWLLPKTVGLQQAKRLVLLADMIDADEAHGLGL
MAB_0905|M.abscessus_ATCC_1997 KFGTAFTGIGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGL
MMAR_3510|M.marinum_M SFAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
MUL_2758|M.ulcerans_Agy99 SFAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
Mvan_2877|M.vanbaalenii_PYR-1 SFAESFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGL
MSMEG_6774|M.smegmatis_MC2_155 RFAESFLRLGLVSGIGGAWFLTRIVGVAKAMELTLTSEFITAETAHELRI
Mb1099c|M.bovis_AF2122/97 KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGL
Rv1070c|M.tuberculosis_H37Rv KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGL
MLBr_02402|M.leprae_Br4923 KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGL
: *: . . * : : * : : . : * * :
MAV_2641|M.avium_104 VNRVVSAADFDATVADFAGRLAGAPTSAIAFTKRLLNDSPDTDRSGAFVA
TH_2877|M.thermoresistible__bu VNKVVPDDQLTAEVTAWAQRLARGATRGIAAAKAMLNQALDVDRAAAFAT
Mflv_2444|M.gilvum_PYR-GCK VTWVKPAGEIDGFIDELADRLAAGPPFALAQSKALLNDGATATLREALAN
MAB_0905|M.abscessus_ATCC_1997 VHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLER
MMAR_3510|M.marinum_M VSRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGM
MUL_2758|M.ulcerans_Agy99 VSRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGM
Mvan_2877|M.vanbaalenii_PYR-1 VSRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQESRTGVLESTLGM
MSMEG_6774|M.smegmatis_MC2_155 VSRVVPDEDLDQECLALAHTVAANPPQALRMAKRLVRESAESGLPAALEM
Mb1099c|M.bovis_AF2122/97 VSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLY
Rv1070c|M.tuberculosis_H37Rv VSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLY
MLBr_02402|M.leprae_Br4923 VSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLH
* * . * : . * :. :
MAV_2641|M.avium_104 EAMAQEIQSYSHDSTEGVQAFVEKRPTEFTGW-----------
TH_2877|M.thermoresistible__bu EALLVEQVASTEDVAEGMAAFAEKREASFRGR-----------
Mflv_2444|M.gilvum_PYR-GCK EARAQPGNFATADSAEAYAAFAAKRDPEFSGAWALYEQPEEQR
MAB_0905|M.abscessus_ATCC_1997 EASAQQRLGASRDHSAAVEAFLAKDKPVFVGR-----------
MMAR_3510|M.marinum_M AAAMQPLAHRDPEHQQRIAKWRTR-------------------
MUL_2758|M.ulcerans_Agy99 AAAMQPLAHRDPEHQQRIAKWRTRIAKWRTR------------
Mvan_2877|M.vanbaalenii_PYR-1 AAAMQPLAHRDPEHAARISRWRSS-------------------
MSMEG_6774|M.smegmatis_MC2_155 AASMQAILLCGDEHRSRVQQFLAARN-----------------
Mb1099c|M.bovis_AF2122/97 ERRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-----------
Rv1070c|M.tuberculosis_H37Rv ERRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-----------
MLBr_02402|M.leprae_Br4923 ERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR-----------
: :