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VTAPLRIDRAGRVQTWTIDVPDAANAITGSDFIDAFDAAVDAANADTDISVVILTGAGRFFSAGGNVRDM RDRTGVFGLGPLDQRHGYSSGIQRVPRALQRCEVPVIAAVNGAAIGAGCDLAVMCDLRIAAESAFFAESF VQLGLIPGDGGTWFLPRAVGWARAAEMTLTGDRVDAATALSWGLVNEVLSDDELLPAAHRLAERIAKNPA PAVRMAKRLLLESRTASLDSTLALAAALQPLAHQDPEHHRRVAELTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3390 | - | - | 100% (257) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2880 | - | 3e-95 | 68.27% (249) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_6774 | - | 2e-52 | 44.27% (253) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 4e-32 | 35.84% (226) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2902 | - | 2e-33 | 37.13% (237) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 4e-32 | 35.84% (226) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-32 | 36.12% (227) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 5e-30 | 35.87% (223) | enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 1e-97 | 67.60% (250) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1939 | - | 9e-39 | 38.68% (243) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_3045 | - | 7e-36 | 38.78% (245) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 8e-97 | 67.20% (250) | enoyl-CoA hydratase, EchA8_5 |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 4e-96 | 66.93% (251) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3510|M.marinum_M -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGKDFIAA
MUL_2758|M.ulcerans_Agy99 -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGRDFIAA
Mvan_2877|M.vanbaalenii_PYR-1 MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAA
MSMEG_3390|M.smegmatis_MC2_155 -------------MTAP--LRIDRAGRVQTWTIDVPDAANAITGSDFIDA
TH_3045|M.thermoresistible__bu -----------VKYDLPDVMTVRADGPIRTVTLDRAADLNSVD-ADLHWA
MAV_1939|M.avium_104 -------------------MLSDLTDGIMTITLNRPDAANAVR-PDDRDT
Mb1099c|M.bovis_AF2122/97 --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
Rv1070c|M.tuberculosis_H37Rv --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
MLBr_02402|M.leprae_Br4923 --------------MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNE
MAB_1185c|M.abscessus_ATCC_199 -----------MTSHNFETILTERIDRVAVITLNRPKALNALN-SQVMNE
Mflv_2902|M.gilvum_PYR-GCK -------------MTDYQTITLEQSGPVARITLNRPEAANGMN-GTMTRE
: : *:: . *.:
MMAR_3510|M.marinum_M FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
MUL_2758|M.ulcerans_Agy99 FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
Mvan_2877|M.vanbaalenii_PYR-1 FESAVDTANSDVAVRAVILTGAGKIFSAGGNVKEMADRQGMFGLDAIAQR
MSMEG_3390|M.smegmatis_MC2_155 FDAAVDAANADTDISVVILTGAGRFFSAGGNVRDMRDRTGVFGLGPLDQR
TH_3045|M.thermoresistible__bu LANVWRQLAADTDARVVILTGAGRAFSAGGDLDWITS----FLTDQVARD
MAV_1939|M.avium_104 LIALLEAADADEKVRVVVLRANGKHFCSGADVTALADRRGRGEKRVLEPT
Mb1099c|M.bovis_AF2122/97 VTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADLT---------FA
Rv1070c|M.tuberculosis_H37Rv VTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADLT---------FA
MLBr_02402|M.leprae_Br4923 ITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLT---------FT
MAB_1185c|M.abscessus_ATCC_199 VTTAAAEFDADHGIGAIIITGSEKAFAAGADIKEMSEQS---------FS
Mflv_2902|M.gilvum_PYR-GCK LADAAARCDT-PATKVVVLTGAGRFFCAGGDLKDFASAPS-----RGQHV
. .::: . : *..*.:: : .
MMAR_3510|M.marinum_M QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
MUL_2758|M.ulcerans_Agy99 QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
Mvan_2877|M.vanbaalenii_PYR-1 HAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCDIRVASERAS
MSMEG_3390|M.smegmatis_MC2_155 HGYSSGIQRVPRALQRCEVPVIAAVNGAAIGAGCDLAVMCDLRIAAESAF
TH_3045|M.thermoresistible__bu ESIREGAQIIEEMLR-FPLPVIAAVNGPAVGLGCSVAVLCDIVLIAENAY
MAV_1939|M.avium_104 RRIMNGAQKLVASVLDCNKPVIAAVHGAATGLGAHIVYASDLVIATENAY
Mb1099c|M.bovis_AF2122/97 DAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK
Rv1070c|M.tuberculosis_H37Rv DAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK
MLBr_02402|M.leprae_Br4923 DAFDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAK
MAB_1185c|M.abscessus_ATCC_199 DMFGSDFFSAWGKLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENAT
Mflv_2902|M.gilvum_PYR-GCK KGVADDLHRAISSFARMDAVVITVVNGTAAGAGFSLAVSGDLVLAAESAS
. . * .: * * * * :. *: : :: *
MMAR_3510|M.marinum_M FAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMV
MUL_2758|M.ulcerans_Agy99 FAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMV
Mvan_2877|M.vanbaalenii_PYR-1 FAESFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGLV
MSMEG_3390|M.smegmatis_MC2_155 FAESFVQLGLIPGDGGTWFLPRAVGWARAAEMTLTGDRVDAATALSWGLV
TH_3045|M.thermoresistible__bu LADPHVAVGLVAGDGGAAMWPLLTLVLRSREYLFTGDRIPAATAVELGLA
MAV_1939|M.avium_104 FAESFVKRGLVVDGGGCYLLPRRIGMQKAKEMAFFGERLSAAEALALGLV
Mb1099c|M.bovis_AF2122/97 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLV
Rv1070c|M.tuberculosis_H37Rv FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLV
MLBr_02402|M.leprae_Br4923 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLV
MAB_1185c|M.abscessus_ATCC_199 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLV
Mflv_2902|M.gilvum_PYR-GCK FTMAYTKVGLSPDGSASYYLPRLIGIAKTKQLMLTNRVLSADEASRWGLV
: . *: . .. :: : : . : * * *:.
MMAR_3510|M.marinum_M SRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMA
MUL_2758|M.ulcerans_Agy99 SRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMA
Mvan_2877|M.vanbaalenii_PYR-1 SRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQESRTGVLESTLGMA
MSMEG_3390|M.smegmatis_MC2_155 NEVLSDDELLPAAHRLAERIAKNPAPAVRMAKRLLLESRTASLDSTLALA
TH_3045|M.thermoresistible__bu SRTVPADDLLPEAIRLAERLAAQPAEALRGTKRIVNMYLSQALAGPLQAG
MAV_1939|M.avium_104 NRVVGADEFDAAVADFAGRLAQAPTSAIAFTKRLLNDSPDTDRSGAFVAE
Mb1099c|M.bovis_AF2122/97 SRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYE
Rv1070c|M.tuberculosis_H37Rv SRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYE
MLBr_02402|M.leprae_Br4923 SRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHE
MAB_1185c|M.abscessus_ATCC_199 SRVVATESLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFE
Mflv_2902|M.gilvum_PYR-GCK TEVVADDELAARADALAGQMAATAAGSNGGVKALLLDTFSNGLEQQMELE
...: .: . * : . : .* : :
MMAR_3510|M.marinum_M AAMQPLAHRDPEHQQRIAKWRTR---------
MUL_2758|M.ulcerans_Agy99 AAMQPLAHRDPEHQQRIAKWRTRIAKWRTR--
Mvan_2877|M.vanbaalenii_PYR-1 AAMQPLAHRDPEHAARISRWRSS---------
MSMEG_3390|M.smegmatis_MC2_155 AALQPLAHQDPEHHRRVAELTR----------
TH_3045|M.thermoresistible__bu FAAEVATMRTAEHRDRLLALRERTR-------
MAV_1939|M.avium_104 AMAQEIQSYAHDSKEGVQAFVEKRPTEFTGW-
Mb1099c|M.bovis_AF2122/97 RRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-
Rv1070c|M.tuberculosis_H37Rv RRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-
MLBr_02402|M.leprae_Br4923 RRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR-
MAB_1185c|M.abscessus_ATCC_199 RRIFHSAFGTADQSEGMAAFVEKRPANFIHR-
Mflv_2902|M.gilvum_PYR-GCK GRLIAQRAESADGREGVDAFLAKRKPEFSPGG
: :