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TASEPLLIGASGAAQMWTINLPQVGNAITGSDFIRAFEDAVDAANRDPTVGAVILTGSGKIFSAGGNVKE MADREGMFGLDAIDQRFAYVDGIQRIPRALARLEVPIIAAVNGAAVGAGFDLAMMCDIRVASERASFAES FVQLGLVPGDGGTWFLQRAIGYERAAEMTFTGDRVDAATALDWGLVSRVVPHDELLSAAQDLAARIVRNP ARALRMAKRLLQESRTGVLESTLGMAAAMQPLAHHDGEHARRIEKWRSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2880 | - | - | 100% (260) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_3390 | - | 3e-95 | 68.27% (249) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_6774 | - | 1e-51 | 45.61% (239) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 2e-35 | 40.27% (221) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2117 | - | 3e-31 | 40.28% (216) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 2e-35 | 40.27% (221) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 4e-35 | 41.67% (216) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 3e-30 | 39.23% (209) | enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 1e-112 | 78.88% (251) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1939 | - | 3e-35 | 37.87% (235) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_4102 | - | 2e-33 | 37.77% (233) | PUTATIVE short chain enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 1e-111 | 78.49% (251) | enoyl-CoA hydratase, EchA8_5 |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 1e-116 | 80.69% (259) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3510|M.marinum_M -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGKDFIAA
MUL_2758|M.ulcerans_Agy99 -------------MNTA--LDITTNGPIRTWTINLPDVGNAITGRDFIAA
Mvan_2877|M.vanbaalenii_PYR-1 MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAA
MSMEG_2880|M.smegmatis_MC2_155 -------------MTASEPLLIGASGAAQMWTINLPQVGNAITGSDFIRA
Mb1099c|M.bovis_AF2122/97 --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
Rv1070c|M.tuberculosis_H37Rv --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
MLBr_02402|M.leprae_Br4923 --------------MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNE
TH_4102|M.thermoresistible__bu -----------MSAKNYETILVTREDRVGIITLNRPKALNALN-SQVMTE
MAB_1185c|M.abscessus_ATCC_199 -----------MTSHNFETILTERIDRVAVITLNRPKALNALN-SQVMNE
Mflv_2117|M.gilvum_PYR-GCK ---------------MAPGALTERRGNVLIITINRPEARNAIN-ASVSIA
MAV_1939|M.avium_104 -------------------MLSDLTDGIMTITLNRPDAANAVR-PDDRDT
*:* *.. **: .
MMAR_3510|M.marinum_M FEAAVDDANIDTSVRAVILTGA-GKIFSGGGNVKEMANRDGMFGLDALEQ
MUL_2758|M.ulcerans_Agy99 FEAAVDDANIDTSVRAVILTGA-GKIFSGGGNVKEMANRDGMFGLDALEQ
Mvan_2877|M.vanbaalenii_PYR-1 FESAVDTANSDVAVRAVILTGA-GKIFSAGGNVKEMADRQGMFGLDAIAQ
MSMEG_2880|M.smegmatis_MC2_155 FEDAVDAANRDPTVGAVILTGS-GKIFSAGGNVKEMADREGMFGLDAIDQ
Mb1099c|M.bovis_AF2122/97 VTSAATELDDDPDIGAIIITGS-AKAFAAGADIKEMADLT---FADAFTA
Rv1070c|M.tuberculosis_H37Rv VTSAATELDDDPDIGAIIITGS-AKAFAAGADIKEMADLT---FADAFTA
MLBr_02402|M.leprae_Br4923 ITNAAKELDIDPDVGAILITGS-PKVFAAGADIKEMASLT---FTDAFDA
TH_4102|M.thermoresistible__bu VTDAAAEFDSDPGIGAIIVTGN-EKAFAAGADIKEMADLE---FADVFAA
MAB_1185c|M.abscessus_ATCC_199 VTTAAAEFDADHGIGAIIITGS-EKAFAAGADIKEMSEQS---FSDMFGS
Mflv_2117|M.gilvum_PYR-GCK VGDALQAAQEDPDVRAVILTGAGDKSFCAGADLKAISRG-----ENLFHP
MAV_1939|M.avium_104 LIALLEAADADEKVRVVVLRAN-GKHFCSGADVTALADRRGRGEKRVLEP
. : * : .::: . * *..*.::. :: :
MMAR_3510|M.marinum_M RQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRA
MUL_2758|M.ulcerans_Agy99 RQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRA
Mvan_2877|M.vanbaalenii_PYR-1 RHAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCDIRVASERA
MSMEG_2880|M.smegmatis_MC2_155 RFAYVDGIQRIPRALARLEVPIIAAVNGAAVGAGFDLAMMCDIRVASERA
Mb1099c|M.bovis_AF2122/97 DFFATWGKLAAVR------TPTIAAVAGYALGGGCELAMMCDVLIAADTA
Rv1070c|M.tuberculosis_H37Rv DFFATWGKLAAVR------TPTIAAVAGYALGGGCELAMMCDVLIAADTA
MLBr_02402|M.leprae_Br4923 DFFSAWGKLAAVR------TPMIAAVAGYALGGGCELAMMCDLLIAADTA
TH_4102|M.thermoresistible__bu DFFAPWSKFAATR------TPTIAAVAGYALGGGCELAMMCDLLIAADTA
MAB_1185c|M.abscessus_ATCC_199 DFFSAWGKLGAVR------TPTIAAVSGYALGGGCELAMMCDVIIAAENA
Mflv_2117|M.gilvum_PYR-GCK EH-SEWGFAGYVRHFI--DKPTIAAVNGTALGGGTELALASDLVVAEERA
MAV_1939|M.avium_104 TRRIMNGAQKLVASVLDCNKPVIAAVHGAATGLGAHIVYASDLVIATENA
. * *.*: * * * * .:. .*: :* : *
MMAR_3510|M.marinum_M SFAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
MUL_2758|M.ulcerans_Agy99 SFAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGM
Mvan_2877|M.vanbaalenii_PYR-1 SFAESFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGL
MSMEG_2880|M.smegmatis_MC2_155 SFAESFVQLGLVPGDGGTWFLQRAIGYERAAEMTFTGDRVDAATALDWGL
Mb1099c|M.bovis_AF2122/97 KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGL
Rv1070c|M.tuberculosis_H37Rv KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGL
MLBr_02402|M.leprae_Br4923 KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGL
TH_4102|M.thermoresistible__bu KFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAEEAERSGL
MAB_1185c|M.abscessus_ATCC_199 TFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGL
Mflv_2117|M.gilvum_PYR-GCK KFGLPEVKRGLIAGAGGVFRIVEQLPRKVALELIYTGEPISSADALRWGL
MAV_1939|M.avium_104 YFAESFVKRGLVVDGGGCYLLPRRIGMQKAKEMAFFGERLSAAEALALGL
*. . : *:: . ** : . : * :: * :.: * *:
MMAR_3510|M.marinum_M VSRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGM
MUL_2758|M.ulcerans_Agy99 VSRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGM
Mvan_2877|M.vanbaalenii_PYR-1 VSRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQESRTGVLESTLGM
MSMEG_2880|M.smegmatis_MC2_155 VSRVVPHDELLSAAQDLAARIVRNPARALRMAKRLLQESRTGVLESTLGM
Mb1099c|M.bovis_AF2122/97 VSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLY
Rv1070c|M.tuberculosis_H37Rv VSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLY
MLBr_02402|M.leprae_Br4923 VSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLH
TH_4102|M.thermoresistible__bu VSRVVPADKLLDEAKETAATIAAMSLSAARMAKEAVNRAFETSLAEGLLF
MAB_1185c|M.abscessus_ATCC_199 VSRVVATESLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLF
Mflv_2117|M.gilvum_PYR-GCK INQVVPDGTVVDAALALAERITCNAPLAVRASKRVSYGAIDGVVGSDEPF
MAV_1939|M.avium_104 VNRVVGADEFDAAVADFAGRLAQAPTSAIAFTKRLLNDSPDTDRSGAFVA
:.:** . . * : . : :*. :
MMAR_3510|M.marinum_M AAA----MQPLAHRDPEHQQRIAKWRTR-------
MUL_2758|M.ulcerans_Agy99 AAA----MQPLAHRDPEHQQRIAKWRTRIAKWRTR
Mvan_2877|M.vanbaalenii_PYR-1 AAA----MQPLAHRDPEHAARISRWRSS-------
MSMEG_2880|M.smegmatis_MC2_155 AAA----MQPLAHHDGEHARRIEKWRSV-------
Mb1099c|M.bovis_AF2122/97 ERR---LFHSAFATEDQSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv ERR---LFHSAFATEDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 ERR---LFHSTFVTDDQSEGMAAFIEKRAPQFTHR
TH_4102|M.thermoresistible__bu ERR---VFHSAFATADQSEGMAAFTEKRPPKFTHR
MAB_1185c|M.abscessus_ATCC_199 ERR---IFHSAFGTADQSEGMAAFVEKRPANFIHR
Mflv_2117|M.gilvum_PYR-GCK WKQTFSEFSTLLKTEDAMEGPLAFAQKREPVWKAK
MAV_1939|M.avium_104 EAMA---QEIQSYAHDSKEGVQAFVEKRPTEFTGW
..