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M. smegmatis MC2 155 MSMEG_6731 (-)

annotation: transcriptional regulatory protein
coordinates: 6777839 - 6778417
length: 192

MPATTDTADEILRCARTLIIIGGYNGFSYADIAAVIGIRKASIHHHFPTKVDLVRTLLQNYRAEVEAGIA
EFERRYPNPVDQLRAYVGYWESCVGDPTTSFCVCALLATQIPVLPQELVLELRAHFRALSAWLTSALERG
ARMGAVALTTTAHAEAETFMATMHGAMLSARAYGDPAIFREITTPLVGRLAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6731--100% (192)transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_5718-3e-0729.71% (138) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3360-1e-0624.28% (173) transcriptional regulator, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2184c-4e-0726.19% (168) hypothetical protein Mb2184c
M. gilvum PYR-GCKMflv_0944-1e-0826.80% (194) TetR family transcriptional regulator
M. tuberculosis H37RvRv3160c-2e-0539.62% (53) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0832-2e-0828.88% (187) TetR family transcriptional regulator
M. marinum MMMAR_4674-9e-0738.57% (70) transcriptional regulator
M. avium 104MAV_5253-2e-0630.11% (93) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3734-8e-0726.95% (141) PUTATIVE putative transcriptional regulator, TetR family
M. ulcerans Agy99MUL_0293-6e-0738.57% (70) transcriptional regulator
M. vanbaalenii PYR-1Mvan_2776-2e-0727.07% (181) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4674|M.marinum_M               ----------MTKPRSDTRRRIQEVARELFLRQGVRGTSLQDIADRLGIT
MUL_0293|M.ulcerans_Agy99           ---------MVTKPRSDTRRRIQEVARELFLRQGVRGTSLQDIADRLGIT
MSMEG_6731|M.smegmatis_MC2_155      -----------MPATTDTADEILRCARTLIIIGGYNGFSYADIAAVIGIR
Mflv_0944|M.gilvum_PYR-GCK          ----------MARPRTFDEDEVIEAGRDLFWSQGYAATSIDDLSAATGLG
MAV_5253|M.avium_104                ---MESKRRTQEERSAATRDALIAAARKLWGLRGYTEVGTPEIAAAAGVT
Mvan_2776|M.vanbaalenii_PYR-1       MPAVRRPGRPVGANSDQTRRTILCAARDVIAEHGYRAATFQQIALRAGVS
MAB_0832|M.abscessus_ATCC_1997      ----MDKRQGGRPRDPDKDDAVRETVRRMLAADGYQRTTIPAVARAAGIG
Mb2184c|M.bovis_AF2122/97           --------MPSADVGRQTRAQILRAAMDIASVKGLSGLSIGELAGRLGMS
Rv3160c|M.tuberculosis_H37Rv        -------MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVE
TH_3734|M.thermoresistible__bu      ------VAETRTVDRSSERQHIIDAAYRCLDRNSGSSASITEILDEAGLG
                                                         :           .        :    *: 

MMAR_4674|M.marinum_M               KPALYYHFASREDLVRSIVVPLIEEGERFV-AERERLADGNVRGL---LE
MUL_0293|M.ulcerans_Agy99           KPALYYHFASREDLVRSIVVPLIEEGERFV-AERERLADGNVRGL---LE
MSMEG_6731|M.smegmatis_MC2_155      KASIHHHFPTKVDLVRTLLQNYRAEVEAGI-AEFERRYPNPVDQLRA-YV
Mflv_0944|M.gilvum_PYR-GCK          RGSLYKAFGDKHSMFLRGLEQYCTEAIAGIRAELRDQDLSAYDRLVAHVR
MAV_5253|M.avium_104                RGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDAIRAAV
Mvan_2776|M.vanbaalenii_PYR-1       RPTLHYYFATREQLYEVLLADVRAEVARCA--AEATLAGSLLRQLEVFIA
MAB_0832|M.abscessus_ATCC_1997      APTIYRRWPTQAAMVESAIADRPWPEELAAPSEFRYYLPVLVRAV----V
Mb2184c|M.bovis_AF2122/97           KSGLFRHFGAKEQLQLATVEAAVSVFEAEVVAPAMAAPPG-VDRVRALMH
Rv3160c|M.tuberculosis_H37Rv        QPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTE
TH_3734|M.thermoresistible__bu      TRAFYRNFSTKHDLLLEMFRRDREAVQAQLREAVAR-APTPVEALRSWMT
                                       :.  :  :  :    .                               

MMAR_4674|M.marinum_M               GYFDFHYRHRQDLMLVVVELTLLSDLG----LIDTVLAWRER--LGRLVF
MUL_0293|M.ulcerans_Agy99           GYFDFHYRHRQDLMLVVVELTLLSDLG----LIDTVLARRER--LGRLVF
MSMEG_6731|M.smegmatis_MC2_155      GYWESCVGDPTTSFCVCALLATQIPVL----PQELVLELRAH--FRALSA
Mflv_0944|M.gilvum_PYR-GCK          GRAADVVSDNDLRGCLLAKSAAELSST----DPEVARHVKRT--LDAWLR
MAV_5253|M.avium_104                DAWLEVSADPEVRQLILLDAPSVLGWA----EFRDVAQRYSLGMTEQLLT
Mvan_2776|M.vanbaalenii_PYR-1       EMHRLGGAEPALMGLVVTARVDHRGVL----RHEAATAVVAT-VHAFFDA
MAB_0832|M.abscessus_ATCC_1997      GYFADPATRAAMPGLLVEYYREPSQYV----VLAERTEMPLREAFRRAHA
Mb2184c|M.bovis_AF2122/97           AWVGYLERDVFPGGCFFAAAAADVDSQ----PGPVRDRIAATG--RAGIA
Rv3160c|M.tuberculosis_H37Rv        SLDHLHASPYVLVSILITPDLHQESFV----AERELVAEMERALVGLIET
TH_3734|M.thermoresistible__bu      HMFELVSNPRKRRRVATLYSEEMRRTPGYVRELELVTAADQASIAAILHR
                                                                                      

MMAR_4674|M.marinum_M               GAAPTLGQATRA-----VLAFGGLQDCCMQFPDEP--------YAQLRQY
MUL_0293|M.ulcerans_Agy99           GAAPTLGQATRA-----VLAFGGLQDCCMQFPDEP--------YAQLRQY
MSMEG_6731|M.smegmatis_MC2_155      WLTSALERGARMGAVALTTTAHAEAETFMATMHGA--------MLSARAY
Mflv_0944|M.gilvum_PYR-GCK          ELTATISAAQADGDIPSSTEAKALAALILAVLRGM--------EALRKGG
MAV_5253|M.avium_104                EAIRAGELAEQPVRPLAHVLIGALDEAAMVIATAD--------DPDRARR
Mvan_2776|M.vanbaalenii_PYR-1       VVVDAVRRGELAFDTDAHAVADLLGALFWGLVFHAG----FISGADGAPE
MAB_0832|M.abscessus_ATCC_1997      GAVGSGERADQPGADALFDTIVGMAVYHGVLRGTAD----DALVEQILDV
Mb2184c|M.bovis_AF2122/97           AITADVETAQRRGEIRADIEARQLAFELHAYAMEAN----WALLLLDDDG
Rv3160c|M.tuberculosis_H37Rv        GQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEFAMTALLSDP
TH_3734|M.thermoresistible__bu      GKAEGIFTACTPEADARSIHAAFEAALLDRFHQKS---------TTDAAD
                                            .                                         

MMAR_4674|M.marinum_M               SVEAALAALGV--------------
MUL_0293|M.ulcerans_Agy99           SVEAALAALGV--------------
MSMEG_6731|M.smegmatis_MC2_155      GDPAIFREITTPLVGRLAA------
Mflv_0944|M.gilvum_PYR-GCK          ASAATVKATAEQLVAML--------
MAV_5253|M.avium_104                ETRQVLQRLVDGMFDAR--------
Mvan_2776|M.vanbaalenii_PYR-1       IARQLLRMVGFGLLDTPEPASVDA-
MAB_0832|M.abscessus_ATCC_1997      VDAASSVGRGLHLDETNSDKERKR-
Mb2184c|M.bovis_AF2122/97           AGERARTAIDAALARVGTTQEGVES
Rv3160c|M.tuberculosis_H37Rv        DRLAEIRAAADALEIQTAPPDRGL-
TH_3734|M.thermoresistible__bu      EVEHLLAFFLRGLGVAT--------