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AARSDSKDRMITAARRLFREHGYTGTAMSDVIAESQAPRGSLYFHFPGGKEELATEVVLRYTADVIAHIN RTAGRTDTAREFVADFLAYFRDEIAASDYREGCAVAPIVVESTPASKPLTAVISRGFRDVIAVLSARLVE KAVPDSDADAIAINILTTMEGALIMSRVLRSISPFDTAISMLTTSLSGIAEPRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3360 | - | - | 100% (195) | transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 9e-26 | 35.48% (186) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6764 | - | 5e-17 | 27.62% (181) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 2e-21 | 32.00% (175) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 2e-26 | 34.20% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 2e-21 | 32.00% (175) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 6e-07 | 28.31% (166) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1494 | - | 4e-23 | 34.95% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0436 | - | 2e-24 | 33.86% (189) | transcriptional regulatory protein |
| M. avium 104 | MAV_0149 | - | 5e-21 | 27.81% (169) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3160 | - | 8e-24 | 31.22% (189) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1086 | - | 3e-22 | 34.48% (174) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | 2e-26 | 37.57% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MMAR_0436|M.marinum_M -----------MPSPRERMVISAVLLIRERGARATAISDVLQHSGAPRGS
MUL_1086|M.ulcerans_Agy99 ------------------MVISAVLLIRERGACATAISDVLQHSGAPRGS
Mflv_3287|M.gilvum_PYR-GCK -----------MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGS
MAB_1494|M.abscessus_ATCC_1997 -----------MSTPRERMVASAALLIRERGAHATAISDVLEHSGAPRGS
Mvan_0275|M.vanbaalenii_PYR-1 -------MSPRTSDARERMLDSASTLIREHGASGTSLDDILRHSRAPRGS
MAV_0149|M.avium_104 ----------MATATRERFLTAATGLFRRQGYSGTGLKQIVAESRAPLGS
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
MSMEG_3360|M.smegmatis_MC2_155 --------MAARSDSKDRMITAARRLFREHGYTGTAMSDVIAESQAPRGS
MLBr_02568|M.leprae_Br4923 --MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPM
:: :* :: .* *.: : .: .
Mb0202|M.bovis_AF2122/97 AYHYFPGGRTQLLCEAVDYAGEHVAAMIN--EAEGG--LELLDALIDKYR
Rv0196|M.tuberculosis_H37Rv AYHYFPGGRTQLLCEAVDYAGEHVAAMIN--EAEGG--LELLDALIDKYR
MMAR_0436|M.marinum_M AYHYFPGGRTQLLCEAVDYAGAHVAKIIG--SANRS--LDLLDTLIDQYR
MUL_1086|M.ulcerans_Agy99 AYHYFPGGRTQLLCEAVDYAGAHVAKIIG--SATRS--LDLLDTLIDQYR
Mflv_3287|M.gilvum_PYR-GCK AYHYFPGGRTQLLCEAVDYAAEFMAERLS--RASSS--LRVLDDLFGYYR
MAB_1494|M.abscessus_ATCC_1997 AYHYFPGGRTQLLSEAVDLAGEYIAGMID--AKPSA--VDALDILVASYR
Mvan_0275|M.vanbaalenii_PYR-1 VYHHFPGGRAQLIEEVVDRAGGALAAILG--DAGDATPATTFDVFISTWK
MAV_0149|M.avium_104 LYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTDIGQATVTWFNWAA
TH_3160|M.thermoresistible__bu IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGVWR
MSMEG_3360|M.smegmatis_MC2_155 LYFHFPGGKEELATEVVLRYTADVIAHINRTAGRTDTAREFVADFLAYFR
MLBr_02568|M.leprae_Br4923 LYLYY-GSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFL
* .: ..: :* : .
Mb0202|M.bovis_AF2122/97 QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
Rv0196|M.tuberculosis_H37Rv QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
MMAR_0436|M.marinum_M EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
MUL_1086|M.ulcerans_Agy99 EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
Mflv_3287|M.gilvum_PYR-GCK TQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWSDIIEQ
MAB_1494|M.abscessus_ATCC_1997 KQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWIDLIAD
Mvan_0275|M.vanbaalenii_PYR-1 AGLEASGFRAGCPVLAVAVETNDDAP-----QLTEAAARAFGSWRDALNT
MAV_0149|M.avium_104 RALQETDYADGCPIGTVACEVASSNE-----ALRQATQAVLASWQSRVAA
TH_3160|M.thermoresistible__bu DGLEAGDYAVGCPIVAAALGTERAAR--------DVAGVAFADLTGLISD
MSMEG_3360|M.smegmatis_MC2_155 DEIAASDYREGCAVAPIVVESTPASK-----PLTAVISRGFRDVIAVLSA
MLBr_02568|M.leprae_Br4923 RYIDAN--RASWIVMYIQAMS---------LPAFAQTVREARDQITELVA
: . :
Mb0202|M.bovis_AF2122/97 RFIADGIPPDRAHELAVLATSTLEGA--ILLARVRRDLTPLDLVHRQLRN
Rv0196|M.tuberculosis_H37Rv RFIADGIPPDRAHELAVLATSTLEGA--ILLARVRRDLTPLDLVHRQLRN
MMAR_0436|M.marinum_M RFVSDGIPLDSAHELAVTAMSTLEGA--LLLARVRRDLTPLDVVHRQLRS
MUL_1086|M.ulcerans_Agy99 RFVSDGIPLDSAHELAVTAMSTLEGA--LLLARVRRDLTPLYVVHRQLRS
Mflv_3287|M.gilvum_PYR-GCK RLIADGVPRADAAALAMLVLTSFEGA--IVVARATRDLKPLDLVAGQLAS
MAB_1494|M.abscessus_ATCC_1997 KLVAVGVVRTRADELAILMTTSLEGA--IIIARSTRDITPIDVVHRQLRT
Mvan_0275|M.vanbaalenii_PYR-1 VLRHQGVPPARARRLATLIVAAVEGA--VALSRVERNTQPIDDVARELRA
MAV_0149|M.avium_104 ELIGAGVPTAQARRLATFAVASLEGA--ILLARAHRSTRPLRETGRVVAD
TH_3160|M.thermoresistible__bu KLVSDGMARRRANSVAVLILTAMEGA--LVLAQARRDPAALDAVVDELTL
MSMEG_3360|M.smegmatis_MC2_155 RLVEKAVPDSDADAIAINILTTMEGA--LIMSRVLRSISPFDTAISMLTT
MLBr_02568|M.leprae_Br4923 GLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMIN
: . . :. ** :: . .. . :
Mb0202|M.bovis_AF2122/97 LLLAELPERSR-----------
Rv0196|M.tuberculosis_H37Rv LLLAELPERSR-----------
MMAR_0436|M.marinum_M MLLAQLPEGNRNDHN-------
MUL_1086|M.ulcerans_Agy99 MLLAQLPEGNRNDHN-------
Mflv_3287|M.gilvum_PYR-GCK LIDARTVTRRK-----------
MAB_1494|M.abscessus_ATCC_1997 LIEEAGQ---------------
Mvan_0275|M.vanbaalenii_PYR-1 LIRQATDAS-------------
MAV_0149|M.avium_104 TLRAATDRG-------------
TH_3160|M.thermoresistible__bu LCSGSAD---------------
MSMEG_3360|M.smegmatis_MC2_155 SLSGIAEPRR------------
MLBr_02568|M.leprae_Br4923 LFWHGLKGAPADRDFGPSIVAG