For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSLRMAALGLLVQQPGSGYDLLRRFEKSMANVWPATQSQLYGELNKLAAAGLIEVSAVGPRGRKEYRATD AGRAELLRWITNPQDDPPERSAELLRVFLLGELPPEQAREHLVMLASHSDGEVERLRALEAAIDWAGEPG ADVFSHAALDYGLRMHTMQAQWARDVIARMDTNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6226 | - | - | 100% (174) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6605 | - | 4e-13 | 31.58% (190) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2868 | - | 3e-10 | 28.48% (158) | transcriptional regulator, PadR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 5e-12 | 40.70% (86) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 6e-51 | 57.93% (164) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 6e-12 | 40.70% (86) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 3e-07 | 25.15% (171) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_1326c | - | 1e-09 | 25.28% (178) | hypothetical protein MAB_1326c |
| M. marinum M | MMAR_3454 | - | 9e-54 | 62.57% (171) | putative regulatory protein |
| M. avium 104 | MAV_0135 | - | 1e-12 | 40.00% (100) | transcriptional regulator, PadR family protein |
| M. thermoresistible (build 8) | TH_0324 | - | 4e-08 | 29.88% (164) | transcriptional regulator, PadR family protein |
| M. ulcerans Agy99 | MUL_2728 | - | 2e-52 | 61.40% (171) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 2e-61 | 68.57% (175) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6226|M.smegmatis_MC2_155 --------------MSLRMAALGLLVQQ-PGSGYDLLRRFEKSMANVWP-
Mvan_5461|M.vanbaalenii_PYR-1 --------------MSLRIAALGLLAEG-SASGYDLLKQFEKSMANVWP-
Mflv_1331|M.gilvum_PYR-GCK --MSIVECHRYYSSMSLRMAALGLLAQH-PASGYDLLKKFEVSMANVWP-
MMAR_3454|M.marinum_M --------------MSLRHAALGLLSQE-PGSGYDLLKRFQLSMNNVWP-
MUL_2728|M.ulcerans_Agy99 --------------MSLRHAALGLLSQE-PGSGYDLLKRFQLSMNNVWP-
Mb1209c|M.bovis_AF2122/97 --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
Rv1176c|M.tuberculosis_H37Rv --------------MALPHAILVSLCEQ-ASSGYELARRFDRSIGYFWT-
MAB_1326c|M.abscessus_ATCC_199 --------------MALTHALLLSLAEQ-SGSGYELTNRFDRSIGYFYS-
MAV_0135|M.avium_104 --------------MSLRDAVLAALLEG-ESSGYDLAKDFDASVANFWP-
MLBr_02691|M.leprae_Br4923 ---------------MLELAILGLLIES-PMHGYELRKRLTGLLGAFRA-
TH_0324|M.thermoresistible__bu VTEAVEDAADQPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYSS
* * * **:: . : . .
MSMEG_6226|M.smegmatis_MC2_155 ATQSQLYGELNKLAAAGLIE--VSAVGPRGR---KEYRATDAGRAELLRW
Mvan_5461|M.vanbaalenii_PYR-1 ATQSQLYSELNKLAAGGLIE--VCAVGPRGR---KEYRITDAGRAELQRW
Mflv_1331|M.gilvum_PYR-GCK GTQSQLYSELNKLADDGLIE--VTAIGARGR---KEYAITRPGRDELRRW
MMAR_3454|M.marinum_M ATQSQLYSELNKLAAAGLIK--SSDLGPRGR---KEYAITDAGRAELYRW
MUL_2728|M.ulcerans_Agy99 ATQSQLYSELNKLAAAGLIK--SSDLGPRGR---KEYAITDAGRAELYRW
Mb1209c|M.bovis_AF2122/97 ATHQQIYRTLRVMENNNWVR--ATTVLQHGRPDKKVYAISDSGRAELARW
Rv1176c|M.tuberculosis_H37Rv ATHQQIYRTLRVMENNNWVR--ATTVLQHGRPDKKVYAISDSGRAELARW
MAB_1326c|M.abscessus_ATCC_199 ATHQQIYRTLRRMEDDSWLH--CQVVDQEGRPAKKVYTVAELGYRELSRW
MAV_0135|M.avium_104 ATPQQLYRELDRLAGQGLIR--ARVVHQQRRPNKRMFSLTAAGRAAIRRF
MLBr_02691|M.leprae_Br4923 FSYGSLYPALRRMQADRLITGHVAPAGTPVRRARQVYQLTDAGRRRFSEL
TH_0324|M.thermoresistible__bu PAYSQIYSELKRLEQYGLVT---SRIEGSTR-SRRMYKITDAGLAAVTRW
: .:* * : : * : : : * . .
MSMEG_6226|M.smegmatis_MC2_155 ITN----------PQDDPPERSAELLRVFLLGELPPEQAREHLVMLASHS
Mvan_5461|M.vanbaalenii_PYR-1 VAE----------RQDDPPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEA
Mflv_1331|M.gilvum_PYR-GCK VMD----------FHDDPPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHA
MMAR_3454|M.marinum_M MTS----------PQQDPPVRNAALLRVFLLGQLDPSQARSYLESLLSLS
MUL_2728|M.ulcerans_Agy99 MTS----------PQQDPPVRNAALLRVFLLGQLDPSQAGSYLESLLSLS
Mb1209c|M.bovis_AF2122/97 IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
Rv1176c|M.tuberculosis_H37Rv IAEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAER
MAB_1326c|M.abscessus_ATCC_199 IAS----------SEGTD--MRDLALKVRAATYADSDVVIEQIRAQRNAH
MAV_0135|M.avium_104 TAT----------APRPSVIRDELLIKVQAADAGDMRAVRDAIRERRDWA
MLBr_02691|M.leprae_Br4923 VTD----------TGPDNYTDNGFGVHLAFFNRTPAEARMRILEGRRRRV
TH_0324|M.thermoresistible__bu TNEE---------PVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYA
::: :
MSMEG_6226|M.smegmatis_MC2_155 DGEVERLRALEAAID--WAGEP------GADVFSHAALDYGLRMHTMQAQ
Mvan_5461|M.vanbaalenii_PYR-1 DGEVRRLTELRESLTGGRAADPT-----DESFFGFAALDYGLRLNAMQAE
Mflv_1331|M.gilvum_PYR-GCK ERDLARYEALRDAVP--WNQSD------DDDFYGRAALEFGLRQAAMTAD
MMAR_3454|M.marinum_M EQEKTHYEQIRDAYD--WAEDD-------DSFFARAALEQGLRWAQQEIE
MUL_2728|M.ulcerans_Agy99 EQEKTHYERIRYAYD--WAEDD-------DSFFARAAPEQGLRWAQQEIE
Mb1209c|M.bovis_AF2122/97 VKSLDTYRGIEKRTFA--DPS----ALDGAALHQYLVLRGGIRAEESAID
Rv1176c|M.tuberculosis_H37Rv VKSLDTYRGIEKRTFA--DPS----ALDGAALHQYLVLRGGIRAEESAID
MAB_1326c|M.abscessus_ATCC_199 AAALEGYLHMQKRQFP--APD----QLSGAALHQYLVLRGGIRMEEGFTD
MAV_0135|M.avium_104 TAKLARYQRLRARLLD--GRSEEDYLARAERIGPYLTLIRGISFEEDNIR
MLBr_02691|M.leprae_Br4923 E---ERREGLREAVTR--ASN-------SFDRYTRQLHQLGLESSEREVK
TH_0324|M.thermoresistible__bu DRMQREAATEARHTAEQPAWSYARLALQWSERYYAAERDLALQLIKDLDV
. .:
MSMEG_6226|M.smegmatis_MC2_155 WARDVIARMDTNR----------------------
Mvan_5461|M.vanbaalenii_PYR-1 WARSVIDRLDT------------------------
Mflv_1331|M.gilvum_PYR-GCK WARWVADGIRARQK---------------------
MMAR_3454|M.marinum_M WAKWVIAGLDQRSGVAPAGQG--------------
MUL_2728|M.ulcerans_Agy99 WAKWVIAGLDQRSGVAPAGQG--------------
Mb1209c|M.bovis_AF2122/97 WLDEVAEALQEKR----------------------
Rv1176c|M.tuberculosis_H37Rv WLDEVAEALQEKR----------------------
MAB_1326c|M.abscessus_ATCC_199 WCDEMLSALSSSHVPARTDESEIDE----------
MAV_0135|M.avium_104 WAEHALAVIARRLPTTDADSDAGDSRLVGPATNG-
MLBr_02691|M.leprae_Br4923 WLNELIAAERALLGRVEQT----------------
TH_0324|M.thermoresistible__bu ADRIFTEAEQSGLEWPVREYWYEVERRIAAEKDRE