For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AVRTLVTGAAGFIGSTLVDRLLADGHGVVGLDDLSSGRAENLHSAENSDKFEFVKADIVDADLTGLLAEF KPEVIFHLAAQISVKRSVDDPPFDATVNVVGTVRLAEAARLAGVRKVVHTSSGGSVYGTPPAYPTSEDMP VNPASPYAAGKVAGEVYLNMYRNLYDLDCSHIAPANVYGPRQDPHGEAGVVAIFSEALLAGRTTKIFGDG SDTRDYVFVDDVVDAFVRAGGPAGGGQRFNVGTGVETSTRELHTAIAGAVGAPDEPEFHPPRLGDLRRSR LDNTRAREVLGWQPQVALAEGIAKTVEFFRNKSQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6142 | - | - | 100% (315) | nucleoside-diphosphate-sugar epimerase |
| M. smegmatis MC2 155 | MSMEG_5985 | - | 1e-55 | 39.62% (313) | NAD dependent epimerase/dehydratase family protein |
| M. smegmatis MC2 155 | MSMEG_0386 | - | 7e-30 | 29.65% (344) | NAD dependent epimerase/dehydratase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3658c | galE1 | 1e-132 | 71.70% (311) | UDP-glucose 4-epimerase GALE1 (galactowaldenase) |
| M. gilvum PYR-GCK | Mflv_1401 | - | 2e-28 | 32.59% (313) | UDP-glucose 4-epimerase |
| M. tuberculosis H37Rv | Rv3634c | galE1 | 1e-132 | 71.70% (311) | UDP-glucose 4-epimerase GALE1 (galactowaldenase) |
| M. leprae Br4923 | MLBr_00204 | rmlB2 | 1e-129 | 71.20% (309) | putative sugar-nucleotide dehydratase |
| M. abscessus ATCC 19977 | MAB_0503 | - | 1e-135 | 73.87% (310) | UDP-glucose 4-epimerase GalE1 |
| M. marinum M | MMAR_5133 | galE1 | 1e-136 | 74.43% (309) | UDP-glucose 4-epimerase GalE1 |
| M. avium 104 | MAV_0524 | - | 1e-136 | 73.95% (311) | nucleoside-diphosphate-sugar epimerase |
| M. thermoresistible (build 8) | TH_3729 | - | 4e-26 | 31.56% (320) | PUTATIVE UDP-galactose 4-epimerase |
| M. ulcerans Agy99 | MUL_4210 | galE1 | 1e-136 | 74.11% (309) | UDP-glucose 4-epimerase GalE1 |
| M. vanbaalenii PYR-1 | Mvan_1365 | - | 1e-27 | 30.84% (321) | dTDP-glucose 4,6-dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1401|M.gilvum_PYR-GCK -----MSWLITGGAGYIGSHVARAMLEAG--RDVVVIDDLSSGFESFVPD
TH_3729|M.thermoresistible__bu -----MTWLVTGGAGYIGSHVVRALLEAD--LPVVVIDDLSTGLEKFVPS
MLBr_00204|M.leprae_Br4923 MYGEPVRALVTGAAGFIGSTLVDRLLADG--HTVVGLDNFATGHAANLEH
MAV_0524|M.avium_104 -----MRALVTGAAGFIGSTLVDRLLADG--HTVVGLDNFASGRASNLEH
Mb3658c|M.bovis_AF2122/97 -----MRALVTGAAGFIGSTLVDRLLADG--HSVVGLDNFATGRATNLEH
Rv3634c|M.tuberculosis_H37Rv -----MRALVTGAAGFIGSTLVDRLLADG--HSVVGLDNFATGRATNLEH
MMAR_5133|M.marinum_M -----MRALVTGAAGFIGSTLVDRLLADG--HTVVGLDNFATGRATNLEH
MUL_4210|M.ulcerans_Agy99 -----MRALVTGAAGFIGSTLVDRLLADG--HTVVGLDNFATGRATNLEH
MAB_0503|M.abscessus_ATCC_1997 -----MRAMVTGAAGFIGSTLVDRLLADG--HEVTGLDNLATGKVANLEA
MSMEG_6142|M.smegmatis_MC2_155 ---MAVRTLVTGAAGFIGSTLVDRLLADG--HGVVGLDDLSSGRAENLHS
Mvan_1365|M.vanbaalenii_PYR-1 -----MRLLVTGGAGFIGANFVRTTVQQRPDVQVTVLDSLTYAGSRESLR
: ::**.**:**: .. : *. :*.:: .
Mflv_1401|M.gilvum_PYR-GCK GAAFVEGTLLDAALVDD----TLARFDVDGVIHIAGYKYAGESVKRPLHT
TH_3729|M.thermoresistible__bu EVPLVRGTLLDADLVAR----ALREHRVSGVIHIAGFKYAGVSVQQPLHT
MLBr_00204|M.leprae_Br4923 LASTPALAFVEADIVTADLQTILDEHRPEVVFHLAAQIDVRHSVVDPQFD
MAV_0524|M.avium_104 LVGNPAHVFVEADIVTADLEAILDEHRPEVVFHLAAQIDVRHSVADPQFD
Mb3658c|M.bovis_AF2122/97 LADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFD
Rv3634c|M.tuberculosis_H37Rv LADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFD
MMAR_5133|M.marinum_M LVDNLAHVFVEADIVDADLQAIFEQHRPEVIFHLAAQIDVRHSVADPQFD
MUL_4210|M.ulcerans_Agy99 LVDNLAHVFVEADIVDADLQAIFEQHRPEVIFHLAAQIDVRHSVADPQFD
MAB_0503|M.abscessus_ATCC_1997 AEANAKFTFVKDDIVEADLDAVVAEYSPEVIFHLAAQIDVRHSVADPQFD
MSMEG_6142|M.smegmatis_MC2_155 AENSDKFEFVKADIVDADLTGLLAEFKPEVIFHLAAQISVKRSVDDPPFD
Mvan_1365|M.vanbaalenii_PYR-1 GVDS-QIRLVEGDITDAELVGKLVADS-DAVVHFAAETHVDNALADPEPF
::. :. . . :.*:*. . :: *
Mflv_1401|M.gilvum_PYR-GCK YEQNVSTTVILLQAMEARGVGQ--IVFSSS-AATFGTPDVDIVD---EST
TH_3729|M.thermoresistible__bu YEQNVSAMVTLLKAMQDTGVDM--MVFSSS-AATFGTPDVDLVT---ETT
MLBr_00204|M.leprae_Br4923 ASVNVIGTVRLAEAARHTGVRK--IVHTSSGGSIYGTPSQYPTP---ETV
MAV_0524|M.avium_104 ASVNVIGTVRLAEAARRTGVRK--IVHTSSGGSIYGTPPTYPTP---ETV
Mb3658c|M.bovis_AF2122/97 AAVNVIGTVRLAEAARQTGVRK--IVHTSSGGSIYGTPPEYPTP---ETA
Rv3634c|M.tuberculosis_H37Rv AAVNVIGTVRLAEAARQTGVRK--IVHTSSGGSIYGTPPEYPTP---ETA
MMAR_5133|M.marinum_M ASVNVIGTLRLAEAARLTGVRK--VVHTSSGGSIYGTPPQYPTS---ERV
MUL_4210|M.ulcerans_Agy99 ASVNVIGTLRLAEAARLTGVRK--VVHTSSGGSIYGTPPQYPTS---ERV
MAB_0503|M.abscessus_ATCC_1997 SSVNVVGTVRLAEAARKAGVRK--IVHTSSGGSIYGTPKQIPTS---ETV
MSMEG_6142|M.smegmatis_MC2_155 ATVNVVGTVRLAEAARLAGVRK--VVHTSSGGSVYGTPPAYPTS---EDM
Mvan_1365|M.vanbaalenii_PYR-1 VHSNVLGTFTVLEAVRHASVTKPVRLHHISTDEVYGDLELDDPARFTDAT
** . : :* . .* :. * :* :
Mflv_1401|M.gilvum_PYR-GCK PTTPESPYGETKLIGEWLLRDAGRASGLRHTSLRYFNVVGSGAVELFDAS
TH_3729|M.thermoresistible__bu PTRPESPYGESKLIGEWLLADVGRATGLRHTSLRYFNVVGSGSPELFDVS
MLBr_00204|M.leprae_Br4923 PTDPTSPYAAGKVAGEIYLNTFRHLCGLDCSHIAPANVYGPRQDPYGEAG
MAV_0524|M.avium_104 PTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG
Mb3658c|M.bovis_AF2122/97 PTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG
Rv3634c|M.tuberculosis_H37Rv PTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAG
MMAR_5133|M.marinum_M PTDPASPYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG
MUL_4210|M.ulcerans_Agy99 PTDPASPYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG
MAB_0503|M.abscessus_ATCC_1997 PTDPHSPYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPRQDPHGEAG
MSMEG_6142|M.smegmatis_MC2_155 PVNPASPYAAGKVAGEVYLNMYRNLYDLDCSHIAPANVYGPRQDPHGEAG
Mvan_1365|M.vanbaalenii_PYR-1 PYNPSSPYSSTKAAADMLVRAWVRSYRVAATISNCSNNYGPYQHVEKFIP
* * ***. * .: : . : : * *.
Mflv_1401|M.gilvum_PYR-GCK PHNLFPLVFDMLFRGETPRINGDDYPTPDGTCVRDYIHVSDLALAHVAAA
TH_3729|M.thermoresistible__bu PHNLFPLVFDMLYRGETPRINGDDYPTPDGTCVRDYIHVADLALAHVAAA
MLBr_00204|M.leprae_Br4923 ---VVAIFVQALLSDRPTKVFGD------GTHTRDYVFVDDVVDAFIKAS
MAV_0524|M.avium_104 ---VVAIFAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVKAS
Mb3658c|M.bovis_AF2122/97 ---VVAIFAQALLSGKPTRVFGD------GTNTRDYVFVDDVVDAFVRVS
Rv3634c|M.tuberculosis_H37Rv ---VVAIFAQALLSGKPTRVFGD------GTNTRDYVFVDDVVDAFVRVS
MMAR_5133|M.marinum_M ---VVAIFAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVRAG
MUL_4210|M.ulcerans_Agy99 ---VVAIFAQALLSGKPTKVFGD------GTNTRDYVFVDDVVDAFVKAG
MAB_0503|M.abscessus_ATCC_1997 ---VVAIFAQALLSGRSTKVFGD------GGNTRDYVFVDDVVEAFVRAS
MSMEG_6142|M.smegmatis_MC2_155 ---VVAIFSEALLAGRTTKIFGD------GSDTRDYVFVDDVVDAFVRAG
Mvan_1365|M.vanbaalenii_PYR-1 ------RQITNVLTGRRPELYGT------GANVRDWIHVDDHNSAVWRIL
: .. ..: * * .**::.* * *
Mflv_1401|M.gilvum_PYR-GCK QRLAAGEPVEPVYNLGSGAGTSVREIMTAMRTVTG-VDFEPVVMPRRPGD
TH_3729|M.thermoresistible__bu RRLQAGEPVEPVYNLGSGSGTSVREIMTAIRKVTG-VDFVPEIAPRRPGD
MLBr_00204|M.leprae_Br4923 GDAGGGQ----RFNIGTGIETSDRQLHTAVSAAVG-GPDDPEFHPPRLGD
MAV_0524|M.avium_104 GDAGGGQ----RFNIGTGVETSDRQLHSAVAAAVG-GPDDPEFHPPRLGD
Mb3658c|M.bovis_AF2122/97 ADVGGGL----RFNIGTGKETSDRQLHSAVAAAVG-GPDDPEFHPPRLGD
Rv3634c|M.tuberculosis_H37Rv ADVGGGL----RFNIGTGKETSDRQLHSAVAAAVG-GPDDPEFHPPRLGD
MMAR_5133|M.marinum_M SDVGGGQ----RFNIGTGVETSDRQLHSAVAAAVG-GPDDPEFHPPRLGD
MUL_4210|M.ulcerans_Agy99 SDVGGGQ----RFNIGTGVETSDRQLHSAVAAAVG-GPDDPEFHPPRLGD
MAB_0503|M.abscessus_ATCC_1997 GPDGGGQ----RFNVGTGVETSDRQLHSLVAAAAG-APDDPEFHPPRLGD
MSMEG_6142|M.smegmatis_MC2_155 GPAGGGQ----RFNVGTGVETSTRELHTAIAGAVG-APDEPEFHPPRLGD
Mvan_1365|M.vanbaalenii_PYR-1 HDGTVGR----TYLIGADGERDNLSVMRTILRLMGRSPEDFDHVTDRVGH
* : :*:. . .: : * . * *.
Mflv_1401|M.gilvum_PYR-GCK PARIVAAGDLAARDLGWSNRHS-LEEMVASAWRARQHAGDAYPR------
TH_3729|M.thermoresistible__bu PARIVASGELAARDLGWRMRHT-LEDMVKSAWEARQRAGDAYPR------
MLBr_00204|M.leprae_Br4923 LKRSCLDIGLATTVLGWSPQVQ-LDDGVRRTVEYFRAAQRS---------
MAV_0524|M.avium_104 LKRSCLDIGLAARVLGWQPKVG-LQQGVARTVEYFRNQHN----------
Mb3658c|M.bovis_AF2122/97 LKRSCLDIGLAERVLGWRPQIE-LADGVRRTVEYFRHKHTD---------
Rv3634c|M.tuberculosis_H37Rv LKRSCLDIGLAERVLGWRPQIE-LADGVRRTVEYFRHKHTD---------
MMAR_5133|M.marinum_M LKRSCLDISRAEEVLGWRPQVE-LADGVRRTVDYFRRTHGS---------
MUL_4210|M.ulcerans_Agy99 LKRSCLDISRAEEVLGWRPQVE-LADGVRRTVDYFRRTHGS---------
MAB_0503|M.abscessus_ATCC_1997 LRQSCLDVGLAKRVLGWEPRVP-LADGIRRTVDFFRS-------------
MSMEG_6142|M.smegmatis_MC2_155 LRRSRLDNTRAREVLGWQPQVA-LAEGIAKTVEFFRNKSQ----------
Mvan_1365|M.vanbaalenii_PYR-1 DLRYAIDPTPLRDELGWRPEHTDFESGLRDTIDWYRDNESWWGPLKDAVE
: *** . : . : : :
Mflv_1401|M.gilvum_PYR-GCK --------
TH_3729|M.thermoresistible__bu --------
MLBr_00204|M.leprae_Br4923 --------
MAV_0524|M.avium_104 --------
Mb3658c|M.bovis_AF2122/97 --------
Rv3634c|M.tuberculosis_H37Rv --------
MMAR_5133|M.marinum_M --------
MUL_4210|M.ulcerans_Agy99 --------
MAB_0503|M.abscessus_ATCC_1997 --------
MSMEG_6142|M.smegmatis_MC2_155 --------
Mvan_1365|M.vanbaalenii_PYR-1 ATYQRRRR